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Stephen Baylin

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Disorders

Chemicals & Drugs

Anatomy

Genes & Molecular Sequences

Tumor Suppressor Genes

Phenomena

Methylation

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Network (preview)

Co-Publications
Name
101
Herman, James
60
Nelkin, Barry
29
Issa, Jean-Pierre
23
Luk, GD
22
Schuebel, Kornel
21
Esteller, Manel
19
Ball, Douglas
15
Gabrielson, Edward
15
Mabry, M
14
Brock, Malcolm
14
Belinsky, Steven
13
AHUJA, NITA
12
Yen, Ray-Whay Chiu
12
Jair, Kam-Wing
12
Vertino, Paula

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Publications

TOP 3
Mohammad Helai P; Cai Yi; McGarvey Kelly M; Easwaran Hariharan; Van Neste Leander; Ohm Joyce E; O'Hagan Heather M; Baylin Stephen B
Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation.
Bailey Vasudev J; Easwaran Hariharan; Zhang Yi; Griffiths Elizabeth; Belinsky Steven A; Herman James G; Baylin Stephen B; Carraway Hetty E; Wang Tza-Huei
MS-qFRET: a quantum dot-based method for analysis of DNA methylation.
Tessema Mathewos; Yu Yang Y; Stidley Christine A; Machida Emi O; Schuebel Kornel E; Baylin Stephen B; Belinsky Steven A
Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers.

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All Publications

2009: Mohammad Helai P; Cai Yi; McGarvey Kelly M; Easwaran Hariharan; Van Neste Leander; Ohm Joyce E; O'Hagan Heather M; Baylin Stephen B
Polycomb CBX7 promotes initiation of heritable repression of genes frequently silenced with cancer-specific DNA hypermethylation.
Cancer research 2009;69(15):6322-30.
2009: Bailey Vasudev J; Easwaran Hariharan; Zhang Yi; Griffiths Elizabeth; Belinsky Steven A; Herman James G; Baylin Stephen B; Carraway Hetty E; Wang Tza-Huei
MS-qFRET: a quantum dot-based method for analysis of DNA methylation.
Genome research 2009;19(8):1455-61.
2009: Tessema Mathewos; Yu Yang Y; Stidley Christine A; Machida Emi O; Schuebel Kornel E; Baylin Stephen B; Belinsky Steven A
Concomitant promoter methylation of multiple genes in lung adenocarcinomas from current, former and never smokers.
Carcinogenesis 2009;30(7):1132-8.
2009: Hellebrekers Debby M E I; Lentjes Marjolein H F M; van den Bosch Sandra M; Melotte Veerle; Wouters Kim A D; Daenen Kathleen L J; Smits Kim M; Akiyama Yoshimitsu; Yuasa Yasuhito; Sanduleanu Silvia; Khalid-de Bakker Carolina A J; Jonkers Daisy; Weijenberg Matty P; Louwagie Joost; van Criekinge Wim; Carvalho Beatriz; Meijer Gerrit A; Baylin Stephen B; Herman James G; de Bruïne Adriaan P; van Engeland Manon
GATA4 and GATA5 are potential tumor suppressors and biomarkers in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):3990-7.
2009: Glöckner Sabine C; Dhir Mashaal; Yi Joo Mi; McGarvey Kelly E; Van Neste Leander; Louwagie Joost; Chan Timothy A; Kleeberger Wolfram; de Bruïne Adriaan P; Smits Kim M; Khalid-de Bakker Carolina A J; Jonkers Daisy M A E; Stockbrügger Reinhold W; Meijer Gerrit A; Oort Frank A; Iacobuzio-Donahue Christine; Bierau Katja; Herman James G; Baylin Stephen B; Van Engeland Manon; Schuebel Kornel E; Ahuja Nita
Methylation of TFPI2 in stool DNA: a potential novel biomarker for the detection of colorectal cancer.
Cancer research 2009;69(11):4691-9.
2009: Zhang Yi; Bailey Vasudev; Puleo Christopher M; Easwaran Hariharan; Griffiths Elizabeth; Herman James G; Baylin Stephen B; Wang Tza-Huei
DNA methylation analysis on a droplet-in-oil PCR array.
Lab on a chip 2009;9(8):1059-64.
2008: Tiwari Vijay K; McGarvey Kelly M; Licchesi Julien D F; Ohm Joyce E; Herman James G; Schübeler Dirk; Baylin Stephen B
PcG proteins, DNA methylation, and gene repression by chromatin looping.
PLoS biology 2008;6(12):2911-27.
2008: Yi Joo Mi; Tsai Hsing-Chen; Glöckner Sabine C; Lin Steven; Ohm Joyce E; Easwaran Hari; James C David; Costello Joseph F; Riggins Gregory; Eberhart Charles G; Laterra John; Vescovi Angelo L; Ahuja Nita; Herman James G; Schuebel Kornel E; Baylin Stephen B
Abnormal DNA methylation of CD133 in colorectal and glioblastoma tumors.
Cancer research 2008;68(19):8094-103.
2008: Dhir Mashaal; Montgomery Elizabeth A; Glöckner Sabine C; Schuebel Kornel E; Hooker Craig M; Herman James G; Baylin Stephen B; Gearhart Susan L; Ahuja Nita
Epigenetic regulation of WNT signaling pathway genes in inflammatory bowel disease (IBD) associated neoplasia.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(10):1745-53.
2008: McGarvey Kelly M; Van Neste Leander; Cope Leslie; Ohm Joyce E; Herman James G; Van Criekinge Wim; Schuebel Kornel E; Baylin Stephen B
Defining a chromatin pattern that characterizes DNA-hypermethylated genes in colon cancer cells.
Cancer research 2008;68(14):5753-9.
2008: Tiwari Vijay K; Cope Leslie; McGarvey Kelly M; Ohm Joyce E; Baylin Stephen B
A novel 6C assay uncovers Polycomb-mediated higher order chromatin conformations.
Genome research 2008;18(7):1171-9.
2008: Jiemjit A; Fandy T E; Carraway H; Bailey K A; Baylin S; Herman J G; Gore S D
p21(WAF1/CIP1) induction by 5-azacytosine nucleosides requires DNA damage.
Oncogene 2008;27(25):3615-23.
2008: Chan Timothy A; Glockner Sabine; Yi Joo Mi; Chen Wei; Van Neste Leander; Cope Leslie; Herman James G; Velculescu Victor; Schuebel Kornel E; Ahuja Nita; Baylin Stephen B
Convergence of mutation and epigenetic alterations identifies common genes in cancer that predict for poor prognosis.
PLoS medicine 2008;5(5):e114.
2008: Licchesi Julien D F; Westra William H; Hooker Craig M; Machida Emi O; Baylin Stephen B; Herman James G
Epigenetic alteration of Wnt pathway antagonists in progressive glandular neoplasia of the lung.
Carcinogenesis 2008;29(5):895-904.
2008: Zhang Wei; Glöckner Sabine C; Guo Mingzhou; Machida Emi Ota; Wang David H; Easwaran Hariharan; Van Neste Leander; Herman James G; Schuebel Kornel E; Watkins D Neil; Ahuja Nita; Baylin Stephen B
Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer.
Cancer research 2008;68(8):2764-72.
2008: Ting Angela H; Suzuki Hiromu; Cope Leslie; Schuebel Kornel E; Lee Byron H; Toyota Minoru; Imai Kohzoh; Shinomura Yasuhisa; Tokino Takashi; Baylin Stephen B
A requirement for DICER to maintain full promoter CpG island hypermethylation in human cancer cells.
Cancer research 2008;68(8):2570-5.
2008: Briggs Kimberly J; Corcoran-Schwartz Ian M; Zhang Wei; Harcke Thomas; Devereux Wendy L; Baylin Stephen B; Eberhart Charles G; Watkins D Neil
Cooperation between the Hic1 and Ptch1 tumor suppressors in medulloblastoma.
Genes & development 2008;22(6):770-85.
2008: Tessema Mathewos; Willink Randy; Do Kieu; Yu Yang Y; Yu Wayne; Machida Emi O; Brock Malcolm; Van Neste Leander; Stidley Christine A; Baylin Stephen B; Belinsky Steven A
Promoter methylation of genes in and around the candidate lung cancer susceptibility locus 6q23-25.
Cancer research 2008;68(6):1707-14.
2008: Brock Malcolm V; Hooker Craig M; Ota-Machida Emi; Han Yu; Guo Mingzhou; Ames Stephen; Glöckner Sabine; Piantadosi Steven; Gabrielson Edward; Pridham Genevieve; Pelosky Kristen; Belinsky Steven A; Yang Stephen C; Baylin Stephen B; Herman James G
DNA methylation markers and early recurrence in stage I lung cancer.
The New England journal of medicine 2008;358(11):1118-28.
2008: Suzuki H; Toyota M; Carraway H; Gabrielson E; Ohmura T; Fujikane T; Nishikawa N; Sogabe Y; Nojima M; Sonoda T; Mori M; Hirata K; Imai K; Shinomura Y; Baylin S B; Tokino T
Frequent epigenetic inactivation of Wnt antagonist genes in breast cancer.
British journal of cancer 2008;98(6):1147-56.
2008: Winter Jordan M; Ting Angela H; Vilardell Felip; Gallmeier Eike; Baylin Steve B; Hruban Ralph H; Kern Scott E; Iacobuzio-Donahue Christine A
Absence of E-cadherin expression distinguishes noncohesive from cohesive pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):412-8.
2008: O'Hagan Heather M; Mohammad Helai P; Baylin Stephen B
Double strand breaks can initiate gene silencing and SIRT1-dependent onset of DNA methylation in an exogenous promoter CpG island.
PLoS genetics 2008;4(8):e1000155.
2007: Riojas Marco A; Guo Mingzhou; Glöckner Sabine C; Machida Emi Ota; Baylin Stephen B; Ahuja Nita
Methylation-induced silencing of ASC/TMS1, a pro-apoptotic gene, is a late-stage event in colorectal cancer.
Cancer biology & therapy 2007;6(11):1710-6.
2007: Schuebel Kornel E; Chen Wei; Cope Leslie; Glöckner Sabine C; Suzuki Hiromu; Yi Joo-Mi; Chan Timothy A; Van Neste Leander; Van Criekinge Wim; van den Bosch Sandra; van Engeland Manon; Ting Angela H; Jair Kamwing; Yu Wayne; Toyota Minoru; Imai Kohzoh; Ahuja Nita; Herman James G; Baylin Stephen B
Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.
PLoS genetics 2007;3(9):1709-23.
2007: Baylin Stephen B; Schuebel Kornel E
Genomic biology: the epigenomic era opens.
Nature 2007;448(7153):548-9.
2007: McGarvey Kelly M; Greene Eriko; Fahrner Jill A; Jenuwein Thomas; Baylin Stephen B
DNA methylation and complete transcriptional silencing of cancer genes persist after depletion of EZH2.
Cancer research 2007;67(11):5097-102.
2007: Huang Yi; Greene Eriko; Murray Stewart Tracy; Goodwin Andrew C; Baylin Stephen B; Woster Patrick M; Casero Robert A
Inhibition of lysine-specific demethylase 1 by polyamine analogues results in reexpression of aberrantly silenced genes.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):8023-8.
2007: Ohm Joyce E; Baylin Stephen B
Stem cell chromatin patterns: an instructive mechanism for DNA hypermethylation?
Cell cycle (Georgetown, Tex.) 2007;6(9):1040-3.
2007: Biankin Sandra A; Collector Michael I; Biankin Andrew V; Brown Lindsey J; Kleeberger Wolfram; Devereux Wendy L; Zahnow Cynthia A; Baylin Stephen B; Watkins D Neil; Sharkis Saul J; Leach Steven D
A histological survey of green fluorescent protein expression in 'green' mice: implications for stem cell research.
Pathology 2007;39(2):247-51.
2007: Gibbons M Chris; Brock Malcolm; Alberg Anthony J; Glass Thomas; LaVeist Thomas A; Baylin Stephen; Levine David; Fox C Earl
The sociobiologic integrative model (SBIM): enhancing the integration of sociobehavioral, environmental, and biomolecular knowledge in urban health and disparities research.
Journal of urban health : bulletin of the New York Academy of Medicine 2007;84(2):198-211.
2007: Jones Peter A; Baylin Stephen B
The epigenomics of cancer.
Cell 2007;128(4):683-92.
2007: Ohm Joyce E; McGarvey Kelly M; Yu Xiaobing; Cheng Linzhao; Schuebel Kornel E; Cope Leslie; Mohammad Helai P; Chen Wei; Daniel Vincent C; Yu Wayne; Berman David M; Jenuwein Thomas; Pruitt Kevin; Sharkis Saul J; Watkins D Neil; Herman James G; Baylin Stephen B
A stem cell-like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing.
Nature genetics 2007;39(2):237-42.
2007: Brock Malcolm V; Herman James G; Baylin Stephen B
Cancer as a manifestation of aberrant chromatin structure.
Cancer journal (Sudbury, Mass.) 2007;13(1):3-8.
2007: Zinn Rebekah L; Pruitt Kevin; Eguchi Sayaka; Baylin Stephen B; Herman James G
hTERT is expressed in cancer cell lines despite promoter DNA methylation by preservation of unmethylated DNA and active chromatin around the transcription start site.
Cancer research 2007;67(1):194-201.
2006: Ting Angela H; McGarvey Kelly M; Baylin Stephen B
The cancer epigenome--components and functional correlates.
Genes & development 2006;20(23):3215-31.
2006: Guo MingZhou; House Michael G; Akiyama Yoshimitsu; Qi Yu; Capagna Domenico; Harmon John; Baylin Stephen B; Brock Malcolm V; Herman James G
Hypermethylation of the GATA gene family in esophageal cancer.
International journal of cancer. Journal international du cancer 2006;119(9):2078-83.
2006: Singh Anju; Misra Vikas; Thimmulappa Rajesh K; Lee Hannah; Ames Stephen; Hoque Mohammad O; Herman James G; Baylin Stephen B; Sidransky David; Gabrielson Edward; Brock Malcolm V; Biswal Shyam
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
PLoS medicine 2006;3(10):e420.
2006: Brock Malcolm V; Hooker Craig M; Engels Eric A; Moore Richard D; Gillison Maura L; Alberg Anthony J; Keruly Jeanne C; Yang Stephen C; Heitmiller Richard F; Baylin Stephen B; Herman James G; Brahmer Julie R
Delayed diagnosis and elevated mortality in an urban population with HIV and lung cancer: implications for patient care.
Journal of acquired immune deficiency syndromes (1999) 2006;43(1):47-55.
2006: Schuebel Kornel; Chen Wei; Baylin Stephen B
CIMPle origin for promoter hypermethylation in colorectal cancer?
Nature genetics 2006;38(7):738-40.
2006: Gore Steven D; Baylin Stephen; Sugar Elizabeth; Carraway Hetty; Miller Carole B; Carducci Michael; Grever Michael; Galm Oliver; Dauses Tianna; Karp Judith E; Rudek Michelle A; Zhao Ming; Smith B Douglas; Manning Jasper; Jiemjit Anchalee; Dover George; Mays Abbie; Zwiebel James; Murgo Anthony; Weng Li-Jun; Herman James G
Combined DNA methyltransferase and histone deacetylase inhibition in the treatment of myeloid neoplasms.
Cancer research 2006;66(12):6361-9.
2006: Machida Emi Ota; Brock Malcolm V; Hooker Craig M; Nakayama Jun; Ishida Akiko; Amano Jun; Picchi Maria A; Belinsky Steven A; Herman James G; Taniguchi Shun'ichiro; Baylin Stephen B
Hypermethylation of ASC/TMS1 is a sputum marker for late-stage lung cancer.
Cancer research 2006;66(12):6210-8.
2006: McGarvey Kelly M; Fahrner Jill A; Greene Eriko; Martens Joost; Jenuwein Thomas; Baylin Stephen B
Silenced tumor suppressor genes reactivated by DNA demethylation do not return to a fully euchromatic chromatin state.
Cancer research 2006;66(7):3541-9.
2006: Wen X-Z; Akiyama Y; Baylin S B; Yuasa Y
Frequent epigenetic silencing of the bone morphogenetic protein 2 gene through methylation in gastric carcinomas.
Oncogene 2006;25(18):2666-73.
2006: Pruitt Kevin; Zinn Rebekah L; Ohm Joyce E; McGarvey Kelly M; Kang Sung-Hae L; Watkins D Neil; Herman James G; Baylin Stephen B
Inhibition of SIRT1 reactivates silenced cancer genes without loss of promoter DNA hypermethylation.
PLoS genetics 2006;2(3):e40.
2006: Belinsky Steven A; Liechty Kieu C; Gentry Frederick D; Wolf Holly J; Rogers Justin; Vu Kieu; Haney Jerry; Kennedy Tim C; Hirsch Fred R; Miller York; Franklin Wilbur A; Herman James G; Baylin Stephen B; Bunn Paul A; Byers Tim
Promoter hypermethylation of multiple genes in sputum precedes lung cancer incidence in a high-risk cohort.
Cancer research 2006;66(6):3338-44.
2006: Hellebrekers Debby M E I; Jair Kam-Wing; Viré Emmanuelle; Eguchi Sayaka; Hoebers Nicole T H; Fraga Mario F; Esteller Manel; Fuks François; Baylin Stephen B; van Engeland Manon; Griffioen Arjan W
Angiostatic activity of DNA methyltransferase inhibitors.
Molecular cancer therapeutics 2006;5(2):467-75.
2006: Baylin Stephen B; Ohm Joyce E
Epigenetic gene silencing in cancer - a mechanism for early oncogenic pathway addiction?
Nature reviews. Cancer 2006;6(2):107-16.
2006: Galm Oliver; Herman James G; Baylin Stephen B
The fundamental role of epigenetics in hematopoietic malignancies.
Blood reviews 2006;20(1):1-13.
2006: Ting Angela H; Jair Kam-wing; Schuebel Kornel E; Baylin Stephen B
Differential requirement for DNA methyltransferase 1 in maintaining human cancer cell gene promoter hypermethylation.
Cancer research 2006;66(2):729-35.
2006: Jair Kam-Wing; Bachman Kurtis E; Suzuki Hiromu; Ting Angela H; Rhee Ina; Yen Ray-Whay Chiu; Baylin Stephen B; Schuebel Kornel E
De novo CpG island methylation in human cancer cells.
Cancer research 2006;66(2):682-92.
2005: Baylin Stephen B
DNA methylation and gene silencing in cancer.
Nature clinical practice. Oncology 2005;2 Suppl 1():S4-11.
2005: Baylin Stephen B; Mufti Ghulam J
Myelodysplastic syndromes (MDSs) and acute myelogenous leukemia (AML) comprise a closely linked continuum of malignant hematologic diseases. Introduction.
Nature clinical practice. Oncology 2005;2 Suppl 1():S1-3.
2005: Chen Wen Yong; Wang David H; Yen Raywhay Chiu; Luo Jianyuan; Gu Wei; Baylin Stephen B
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses.
Cell 2005;123(3):437-48.
2005: Brock Malcolm V; Hooker Craig M; Yung Rex; Guo Mingzhou; Han Yu; Ames Stephen E; Chang David; Yang Stephen C; Mason David; Sussman Marc; Baylin Stephen B; Herman James G
Can we improve the cytologic examination of malignant pleural effusions using molecular analysis?
The Annals of thoracic surgery 2005;80(4):1241-7.
2005: Schuebel Kornel; Baylin Steve
In living color: DNA methyltransferase caught in the act.
Nature methods 2005;2(10):736-8.
2005: Ting Angela H; Schuebel Kornel E; Herman James G; Baylin Stephen B
Short double-stranded RNA induces transcriptional gene silencing in human cancer cells in the absence of DNA methylation.
Nature genetics 2005;37(8):906-10.
2005: Galm Oliver; Suzuki Hiromu; Akiyama Yoshimitsu; Esteller Manel; Brock Malcolm V; Osieka Rainhardt; Baylin Stephen B; Herman James G
Inactivation of the tissue inhibitor of metalloproteinases-2 gene by promoter hypermethylation in lymphoid malignancies.
Oncogene 2005;24(30):4799-805.
2005: Brock Malcolm V; Hooker Craig M; Syphard James E; Westra William; Xu Li; Alberg Anthony J; Mason David; Baylin Stephen B; Herman James G; Yung Rex C; Brahmer Julie; Rudin Charles M; Ettinger David S; Yang Stephen C
Surgical resection of limited disease small cell lung cancer in the new era of platinum chemotherapy: Its time has come.
The Journal of thoracic and cardiovascular surgery 2005;129(1):64-72.
2005: Chen Wen Yong; Baylin Stephen B
Inactivation of tumor suppressor genes: choice between genetic and epigenetic routes.
Cell cycle (Georgetown, Tex.) 2005;4(1):10-2.
2005: Baylin S B; Chen W Y
Aberrant gene silencing in tumor progression: implications for control of cancer.
Cold Spring Harbor symposia on quantitative biology 2005;70():427-33.
2004: Guo Mingzhou; Akiyama Yoshimitsu; House Michael G; Hooker Craig M; Heath Elizabeth; Gabrielson Edward; Yang Stephen C; Han Yu; Baylin Stephen B; Herman James G; Brock Malcolm V
Hypermethylation of the GATA genes in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(23):7917-24.
2004: Chen Wenyong; Cooper Timothy K; Zahnow Cynthia A; Overholtzer Michael; Zhao Zhiquan; Ladanyi Marc; Karp Judith E; Gokgoz Nalan; Wunder Jay S; Andrulis Irene L; Levine Arnold J; Mankowski Joseph L; Baylin Stephen B
Epigenetic and genetic loss of Hic1 function accentuates the role of p53 in tumorigenesis.
Cancer cell 2004;6(4):387-98.
2004: Guo Mingzhou; House Michael G; Hooker Craig; Han Yu; Heath Elizabeth; Gabrielson Edward; Yang Stephen C; Baylin Stephen B; Herman James G; Brock Malcolm V
Promoter hypermethylation of resected bronchial margins: a field defect of changes?
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5131-6.
2004: Ting Angela H; Jair Kam-wing; Suzuki Hiromu; Yen Ray-Whay Chiu; Baylin Stephen B; Schuebel Kornel E
Mammalian DNA methyltransferase 1: inspiration for new directions.
Cell cycle (Georgetown, Tex.) 2004;3(8):1024-6.
2004: Ting Angela H; Jair Kam-wing; Suzuki Hiromu; Yen Ray-Whay Chiu; Baylin Stephen B; Schuebel Kornel E
CpG island hypermethylation is maintained in human colorectal cancer cells after RNAi-mediated depletion of DNMT1.
Nature genetics 2004;36(6):582-4.
2004: Jang Yoon-Young; Collector Michael I; Baylin Stephen B; Diehl Anna Mae; Sharkis Saul J
Hematopoietic stem cells convert into liver cells within days without fusion.
Nature cell biology 2004;6(6):532-9.
2004: Suzuki Hiromu; Watkins D Neil; Jair Kam-Wing; Schuebel Kornel E; Markowitz Sanford D; Chen Wei Dong; Pretlow Theresa P; Yang Bin; Akiyama Yoshimitsu; Van Engeland Manon; Toyota Minoru; Tokino Takashi; Hinoda Yuji; Imai Kohzoh; Herman James G; Baylin Stephen B
Epigenetic inactivation of SFRP genes allows constitutive WNT signaling in colorectal cancer.
Nature genetics 2004;36(4):417-22.
2004: Stoehr Robert; Wissmann Christoph; Suzuki Hiromu; Knuechel Ruth; Krieg Rene C; Klopocki Eva; Dahl Edgar; Wild Peter; Blaszyk Hagen; Sauter Guido; Simon Ronald; Schmitt Ruediger; Zaak Dirk; Hofstaedter Ferdinand; Rosenthal Andre; Baylin Stephen B; Pilarsky Christian; Hartmann Arndt
Deletions of chromosome 8p and loss of sFRP1 expression are progression markers of papillary bladder cancer.
Laboratory investigation; a journal of technical methods and pathology 2004;84(4):465-78.
2004: Douglas Donna B; Akiyama Yoshimitsu; Carraway Hetty; Belinsky Steven A; Esteller Manel; Gabrielson Edward; Weitzman Sigmund; Williams Trevor; Herman James G; Baylin Stephen B
Hypermethylation of a small CpGuanine-rich region correlates with loss of activator protein-2alpha expression during progression of breast cancer.
Cancer research 2004;64(5):1611-20.
2004: Baylin Stephen B
Reversal of gene silencing as a therapeutic target for cancer--roles for DNA methylation and its interdigitation with chromatin.
Novartis Foundation symposium 2004;259():226-33; discussion 234-7, 285-8.
2003: Akiyama Yoshimitsu; Watkins Neil; Suzuki Hiromu; Jair Kam-Wing; van Engeland Manon; Esteller Manel; Sakai Hidekazu; Ren Chun-Yan; Yuasa Yasuhito; Herman James G; Baylin Stephen B
GATA-4 and GATA-5 transcription factor genes and potential downstream antitumor target genes are epigenetically silenced in colorectal and gastric cancer.
Molecular and cellular biology 2003;23(23):8429-39.
2003: Herman James G; Baylin Stephen B
Gene silencing in cancer in association with promoter hypermethylation.
The New England journal of medicine 2003;349(21):2042-54.
2003: Belinsky Steven A; Klinge Donna M; Stidley Christine A; Issa Jean-Pierre; Herman James G; March Thomas H; Baylin Stephen B
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
Cancer research 2003;63(21):7089-93.
2003: Brock Malcolm V; Gou Mingzhou; Akiyama Yoshimitsu; Muller Alison; Wu Tsung-Teh; Montgomery Elizabeth; Deasel Mari; Germonpré Paul; Rubinson Lewis; Heitmiller Richard F; Yang Stephen C; Forastiere Arlene A; Baylin Stephen B; Herman James G
Prognostic importance of promoter hypermethylation of multiple genes in esophageal adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2912-9.
2003: Palmisano William A; Crume Kevin P; Grimes Marcie J; Winters Sally A; Toyota Minoru; Esteller Manel; Joste Nancy; Baylin Stephen B; Belinsky Steven A
Aberrant promoter methylation of the transcription factor genes PAX5 alpha and beta in human cancers.
Cancer research 2003;63(15):4620-5.
2003: Fahrner Jill A; Baylin Stephen B
Heterochromatin: stable and unstable invasions at home and abroad.
Genes & development 2003;17(15):1805-12.
2003: van Engeland Manon; Weijenberg Matty P; Roemen Guido M J M; Brink Mirian; de Bruïne Adriaan P; Goldbohm R Alexandra; van den Brandt Piet A; Baylin Stephen B; de Goeij Anton F P M; Herman James G
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancer.
Cancer research 2003;63(12):3133-7.
2003: Watkins D Neil; Berman David M; Baylin Stephen B
Hedgehog signaling: progenitor phenotype in small-cell lung cancer.
Cell cycle (Georgetown, Tex.) 2003;2(3):196-8.
2003: Reese Brian E; Bachman Kurtis E; Baylin Stephen B; Rountree Michael R
The methyl-CpG binding protein MBD1 interacts with the p150 subunit of chromatin assembly factor 1.
Molecular and cellular biology 2003;23(9):3226-36.
2003: Holst Charles R; Nuovo Gerard J; Esteller Manel; Chew Karen; Baylin Stephen B; Herman James G; Tlsty Thea D
Methylation of p16(INK4a) promoters occurs in vivo in histologically normal human mammary epithelia.
Cancer research 2003;63(7):1596-601.
2003: Watkins D Neil; Berman David M; Burkholder Scott G; Wang Baolin; Beachy Philip A; Baylin Stephen B
Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer.
Nature 2003;422(6929):313-7.
2003: Chen Wen Yong; Zeng Xiaobei; Carter Mark G; Morrell Craig N; Chiu Yen Ray-Whay; Esteller Manel; Watkins D Neil; Herman James G; Mankowski Joseph L; Baylin Stephen B
Heterozygous disruption of Hic1 predisposes mice to a gender-dependent spectrum of malignant tumors.
Nature genetics 2003;33(2):197-202.
2003: Bachman Kurtis E; Park Ben Ho; Rhee Ina; Rajagopalan Harith; Herman James G; Baylin Stephen B; Kinzler Kenneth W; Vogelstein Bert
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene.
Cancer cell 2003;3(1):89-95.
2002: Fahrner Jill A; Eguchi Sayaka; Herman James G; Baylin Stephen B
Dependence of histone modifications and gene expression on DNA hypermethylation in cancer.
Cancer research 2002;62(24):7213-8.
2002: Esteller Manel; Guo Mingzhou; Moreno Victor; Peinado Miquel Angel; Capella Gabriel; Galm Oliver; Baylin Stephen B; Herman James G
Hypermethylation-associated Inactivation of the Cellular Retinol-Binding-Protein 1 Gene in Human Cancer.
Cancer research 2002;62(20):5902-5.
2002: Cameron Elizabeth; Mijovic Aleksandar; Herman James G; Baylin Stephen B; Pradhan Anjala; Mufti Ghulam J; Rassool Feyruz V
P15INK4B is not mutated in adult familial myelodysplastic syndromes.
British journal of haematology 2002;119(1):277-9.
2002: Baylin Stephen B
Mechanisms underlying epigenetically mediated gene silencing in cancer.
Seminars in cancer biology 2002;12(5):331-7.
2002: Jones Peter A; Baylin Stephen B
The fundamental role of epigenetic events in cancer.
Nature reviews. Genetics 2002;3(6):415-28.
2002: Suzuki Hiromu; Gabrielson Edward; Chen Wei; Anbazhagan Ramaswamy; van Engeland Manon; Weijenberg Matty P; Herman James G; Baylin Stephen B
A genomic screen for genes upregulated by demethylation and histone deacetylase inhibition in human colorectal cancer.
Nature genetics 2002;31(2):141-9.
2002: Baylin Stephen; Bestor Timothy H
Altered methylation patterns in cancer cell genomes: cause or consequence?
Cancer cell 2002;1(4):299-305.
2002: Rhee Ina; Bachman Kurtis E; Park Ben Ho; Jair Kam-Wing; Yen Ray-Whay Chiu; Schuebel Kornel E; Cui Hengmi; Feinberg Andrew P; Lengauer Christoph; Kinzler Kenneth W; Baylin Stephen B; Vogelstein Bert
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells.
Nature 2002;416(6880):552-6.
2002: van Noesel Max M; van Bezouw Saskia; Salomons Gajja S; Voûte P A; Pieters Rob; Baylin Steve B; Herman James G; Versteeg Rogier
Tumor-specific down-regulation of the tumor necrosis factor-related apoptosis-inducing ligand decoy receptors DcR1 and DcR2 is associated with dense promoter hypermethylation.
Cancer research 2002;62(7):2157-61.
2002: Galm Oliver; Rountree Michael R; Bachman Kurtis E; Jair Kam-Wing; Baylin Stephen B; Herman James G
Enzymatic regional methylation assay: a novel method to quantify regional CpG methylation density.
Genome research 2002;12(1):153-7.
2002: Esteller Manel; Gaidano Gianluca; Goodman Steven N; Zagonel Vittorina; Capello Daniela; Botto Barbara; Rossi Davide; Gloghini Annunziata; Vitolo Umberto; Carbone Antonino; Baylin Stephen B; Herman James G
Hypermethylation of the DNA repair gene O(6)-methylguanine DNA methyltransferase and survival of patients with diffuse large B-cell lymphoma.
Journal of the National Cancer Institute 2002;94(1):26-32.
2001: Esteller M; Fraga M F; Guo M; Garcia-Foncillas J; Hedenfalk I; Godwin A K; Trojan J; Vaurs-Barrière C; Bignon Y J; Ramus S; Benitez J; Caldes T; Akiyama Y; Yuasa Y; Launonen V; Canal M J; Rodriguez R; Capella G; Peinado M A; Borg A; Aaltonen L A; Ponder B A; Baylin S B; Herman J G
DNA methylation patterns in hereditary human cancers mimic sporadic tumorigenesis.
Human molecular genetics 2001;10(26):3001-7.
2001: Bachman K E; Rountree M R; Baylin S B
Dnmt3a and Dnmt3b are transcriptional repressors that exhibit unique localization properties to heterochromatin.
The Journal of biological chemistry 2001;276(34):32282-7.
2001: Esteller M; Risques R A; Toyota M; Capella G; Moreno V; Peinado M A; Baylin S B; Herman J G
Promoter hypermethylation of the DNA repair gene O(6)-methylguanine-DNA methyltransferase is associated with the presence of G:C to A:T transition mutations in p53 in human colorectal tumorigenesis.
Cancer research 2001;61(12):4689-92.
2001: Herman J G; Baylin S B
Methylation-specific PCR.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 10():Unit 10.6.
2001: Rountree M R; Bachman K E; Herman J G; Baylin S B
DNA methylation, chromatin inheritance, and cancer.
Oncogene 2001;20(24):3156-65.
2001: Baylin S B; Herman J G
Promoter hypermethylation--can this change alone ever designate true tumor suppressor gene function?
Journal of the National Cancer Institute 2001;93(9):664-5.
2001: Esteller M; Corn P G; Baylin S B; Herman J G
A gene hypermethylation profile of human cancer.
Cancer research 2001;61(8):3225-9.
2001: Sriuranpong V; Borges M W; Ravi R K; Arnold D R; Nelkin B D; Baylin S B; Ball D W
Notch signaling induces cell cycle arrest in small cell lung cancer cells.
Cancer research 2001;61(7):3200-5.
2001: Esteller M; Cordon-Cardo C; Corn P G; Meltzer S J; Pohar K S; Watkins D N; Capella G; Peinado M A; Matias-Guiu X; Prat J; Baylin S B; Herman J G
p14ARF silencing by promoter hypermethylation mediates abnormal intracellular localization of MDM2.
Cancer research 2001;61(7):2816-21.
2001: Baylin S B; Esteller M; Rountree M R; Bachman K E; Schuebel K; Herman J G
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer.
Human molecular genetics 2001;10(7):687-92.
2001: Myöhänen S; Baylin S B
Sequence-specific DNA binding activity of RNA helicase A to the p16INK4a promoter.
The Journal of biological chemistry 2001;276(2):1634-42.
2001: Baylin S
DNA methylation and epigenetic mechanisms of carcinogenesis.
Developments in biologicals 2001;106():85-7; discussion 143-60.
2000: Corn P G; Smith B D; Ruckdeschel E S; Douglas D; Baylin S B; Herman J G
E-cadherin expression is silenced by 5' CpG island methylation in acute leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4243-8.
2000: Palmisano W A; Divine K K; Saccomanno G; Gilliland F D; Baylin S B; Herman J G; Belinsky S A
Predicting lung cancer by detecting aberrant promoter methylation in sputum.
Cancer research 2000;60(21):5954-8.
2000: Esteller M; Garcia-Foncillas J; Andion E; Goodman S N; Hidalgo O F; Vanaclocha V; Baylin S B; Herman J G
Inactivation of the DNA-repair gene MGMT and the clinical response of gliomas to alkylating agents.
The New England journal of medicine 2000;343(19):1350-4.
2000: Baylin S B; Belinsky S A; Herman J G
Aberrant methylation of gene promoters in cancer---concepts, misconcepts, and promise.
Journal of the National Cancer Institute 2000;92(18):1460-1.
2000: Esteller M; Sparks A; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Gonzalez S; Tarafa G; Sidransky D; Meltzer S J; Baylin S B; Herman J G
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.
Cancer research 2000;60(16):4366-71.
2000: Linnoila R I; Zhao B; DeMayo J L; Nelkin B D; Baylin S B; DeMayo F J; Ball D W
Constitutive achaete-scute homologue-1 promotes airway dysplasia and lung neuroendocrine tumors in transgenic mice.
Cancer research 2000;60(15):4005-9.
2000: Rountree M R; Bachman K E; Baylin S B
DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci.
Nature genetics 2000;25(3):269-77.
2000: Krasner A; Wallace L; Thiagalingam A; Jones C; Lengauer C; Minahan L; Ma Y; Kalikin L; Feinberg A P; Jabs E W; Tunnacliffe A; Baylin S B; Ball D W; Nelkin B D
Cloning and chromosomal localization of the human BARX2 homeobox protein gene.
Gene 2000;250(1-2):171-80.
2000: Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Watkins D N; Issa J P; Sidransky D; Baylin S B; Herman J G
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Cancer research 2000;60(9):2368-71.
2000: Rhee I; Jair K W; Yen R W; Lengauer C; Herman J G; Kinzler K W; Vogelstein B; Baylin S B; Schuebel K E
CpG methylation is maintained in human cancer cells lacking DNMT1.
Nature 2000;404(6781):1003-7.
2000: Antoun G; Baylin S B; Ali-Osman F
DNA methyltransferase levels and altered CpG methylation in the total genome and in the GSTP1 gene in human glioma cells transfected with sense and antisense DNA methyltransferase cDNA.
Journal of cellular biochemistry 2000;77(3):372-81.
2000: Esteller M; Silva J M; Dominguez G; Bonilla F; Matias-Guiu X; Lerma E; Bussaglia E; Prat J; Harkes I C; Repasky E A; Gabrielson E; Schutte M; Baylin S B; Herman J G
Promoter hypermethylation and BRCA1 inactivation in sporadic breast and ovarian tumors.
Journal of the National Cancer Institute 2000;92(7):564-9.
2000: Baylin S B; Herman J G
DNA hypermethylation in tumorigenesis: epigenetics joins genetics.
Trends in genetics : TIG 2000;16(4):168-74.
2000: Carter M G; Johns M A; Zeng X; Zhou L; Zink M C; Mankowski J L; Donovan D M; Baylin S B
Mice deficient in the candidate tumor suppressor gene Hic1 exhibit developmental defects of structures affected in the Miller-Dieker syndrome.
Human molecular genetics 2000;9(3):413-9.
2000: Eng C; Herman J G; Baylin S B
A bird's eye view of global methylation.
Nature genetics 2000;24(2):101-2.
2000: Esteller M; Tortola S; Toyota M; Capella G; Peinado M A; Baylin S B; Herman J G
Hypermethylation-associated inactivation of p14(ARF) is independent of p16(INK4a) methylation and p53 mutational status.
Cancer research 2000;60(1):129-33.
2000: Esteller M; Avizienyte E; Corn P G; Lothe R A; Baylin S B; Aaltonen L A; Herman J G
Epigenetic inactivation of LKB1 in primary tumors associated with the Peutz-Jeghers syndrome.
Oncogene 2000;19(1):164-8.
2000: Graff J R; Gabrielson E; Fujii H; Baylin S B; Herman J G
Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression.
The Journal of biological chemistry 2000;275(4):2727-32.
2000: Herman J G; Baylin S B
Promoter-region hypermethylation and gene silencing in human cancer.
Current topics in microbiology and immunology 2000;249():35-54.
1999: Toyota M; Ahuja N; Suzuki H; Itoh F; Ohe-Toyota M; Imai K; Baylin S B; Issa J P
Aberrant methylation in gastric cancer associated with the CpG island methylator phenotype.
Cancer research 1999;59(21):5438-42.
1999: Esteller M; Catasus L; Matias-Guiu X; Mutter G L; Prat J; Baylin S B; Herman J G
hMLH1 promoter hypermethylation is an early event in human endometrial tumorigenesis.
The American journal of pathology 1999;155(5):1767-72.
1999: Nuovo G J; Plaia T W; Belinsky S A; Baylin S B; Herman J G
In situ detection of the hypermethylation-induced inactivation of the p16 gene as an early event in oncogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12754-9.
1999: Cameron E E; Baylin S B; Herman J G
p15(INK4B) CpG island methylation in primary acute leukemia is heterogeneous and suggests density as a critical factor for transcriptional silencing.
Blood 1999;94(7):2445-51.
1999: Toyota M; Ho C; Ohe-Toyota M; Baylin S B; Issa J P
Inactivation of CACNA1G, a T-type calcium channel gene, by aberrant methylation of its 5' CpG island in human tumors.
Cancer research 1999;59(18):4535-41.
1999: Corn P G; Kuerbitz S J; van Noesel M M; Esteller M; Compitello N; Baylin S B; Herman J G
Transcriptional silencing of the p73 gene in acute lymphoblastic leukemia and Burkitt's lymphoma is associated with 5' CpG island methylation.
Cancer research 1999;59(14):3352-6.
1999: Toyota M; Ahuja N; Ohe-Toyota M; Herman J G; Baylin S B; Issa J P
CpG island methylator phenotype in colorectal cancer.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(15):8681-6.
1999: Katzenellenbogen R A; Baylin S B; Herman J G
Hypermethylation of the DAP-kinase CpG island is a common alteration in B-cell malignancies.
Blood 1999;93(12):4347-53.
1999: Toyota M; Ho C; Ahuja N; Jair K W; Li Q; Ohe-Toyota M; Baylin S B; Issa J P
Identification of differentially methylated sequences in colorectal cancer by methylated CpG island amplification.
Cancer research 1999;59(10):2307-12.
1999: McGregor L M; McCune B K; Graff J R; McDowell P R; Romans K E; Yancopoulos G D; Ball D W; Baylin S B; Nelkin B D
Roles of trk family neurotrophin receptors in medullary thyroid carcinoma development and progression.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(8):4540-5.
1999: Bachman K E; Herman J G; Corn P G; Merlo A; Costello J F; Cavenee W K; Baylin S B; Graff J R
Methylation-associated silencing of the tissue inhibitor of metalloproteinase-3 gene suggest a suppressor role in kidney, brain, and other human cancers.
Cancer research 1999;59(4):798-802.
1999: Esteller M; Hamilton S R; Burger P C; Baylin S B; Herman J G
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is a common event in primary human neoplasia.
Cancer research 1999;59(4):793-7.
1999: Kuerbitz S J; Malandro J; Compitello N; Baylin S B; Graff J R
Deletion of p16INK4A/CDKN2 and p15INK4B in human somatic cell hybrids and hybrid-derived tumors.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(1):27-33.
1999: Cameron E E; Bachman K E; Myöhänen S; Herman J G; Baylin S B
Synergy of demethylation and histone deacetylase inhibition in the re-expression of genes silenced in cancer.
Nature genetics 1999;21(1):103-7.
1999: Esteller M; Sanchez-Cespedes M; Rosell R; Sidransky D; Baylin S B; Herman J G
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.
Cancer research 1999;59(1):67-70.
1998: Ahuja N; Li Q; Mohan A L; Baylin S B; Issa J P
Aging and DNA methylation in colorectal mucosa and cancer.
Cancer research 1998;58(23):5489-94.
1998: Esteller M; Levine R; Baylin S B; Ellenson L H; Herman J G
MLH1 promoter hypermethylation is associated with the microsatellite instability phenotype in sporadic endometrial carcinomas.
Oncogene 1998;17(18):2413-7.
1998: Esteller M; Corn P G; Urena J M; Gabrielson E; Baylin S B; Herman J G
Inactivation of glutathione S-transferase P1 gene by promoter hypermethylation in human neoplasia.
Cancer research 1998;58(20):4515-8.
1998: Belinsky S A; Nikula K J; Palmisano W A; Michels R; Saccomanno G; Gabrielson E; Baylin S B; Herman J G
Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(20):11891-6.
1998: Narayan A; Ji W; Zhang X Y; Marrogi A; Graff J R; Baylin S B; Ehrlich M
Hypomethylation of pericentromeric DNA in breast adenocarcinomas.
International journal of cancer. Journal international du cancer 1998;77(6):833-8.
1998: Mikovits J A; Young H A; Vertino P; Issa J P; Pitha P M; Turcoski-Corrales S; Taub D D; Petrow C L; Baylin S B; Ruscetti F W
Infection with human immunodeficiency virus type 1 upregulates DNA methyltransferase, resulting in de novo methylation of the gamma interferon (IFN-gamma) promoter and subsequent downregulation of IFN-gamma production.
Molecular and cellular biology 1998;18(9):5166-77.
1998: Carson-Walter E B; Smith D P; Ponder B A; Baylin S B; Nelkin B D
Post-transcriptional silencing of RET occurs, but is not required, during raf-1 mediated differentiation of medullary thyroid carcinoma cells.
Oncogene 1998;17(3):367-76.
1998: Li Q; Jedlicka A; Ahuja N; Gibbons M C; Baylin S B; Burger P C; Issa J P
Concordant methylation of the ER and N33 genes in glioblastoma multiforme.
Oncogene 1998;16(24):3197-202.
1998: Chen H; Roberts J R; Ball D W; Eisele D W; Baylin S B; Udelsman R; Bulkley G B
Effective long-term palliation of symptomatic, incurable metastatic medullary thyroid cancer by operative resection.
Annals of surgery 1998;227(6):887-95.
1998: Herman J G; Umar A; Polyak K; Graff J R; Ahuja N; Issa J P; Markowitz S; Willson J K; Hamilton S R; Kinzler K W; Kane M F; Kolodner R D; Vogelstein B; Kunkel T A; Baylin S B
Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6870-5.
1998: Graff J R; Greenberg V E; Herman J G; Westra W H; Boghaert E R; Ain K B; Saji M; Zeiger M A; Zimmer S G; Baylin S B
Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma.
Cancer research 1998;58(10):2063-6.
1998: Hiraguri S; Godfrey T; Nakamura H; Graff J; Collins C; Shayesteh L; Doggett N; Johnson K; Wheelock M; Herman J; Baylin S; Pinkel D; Gray J
Mechanisms of inactivation of E-cadherin in breast cancer cell lines.
Cancer research 1998;58(9):1972-7.
1998: Fujii H; Biel M A; Zhou W; Weitzman S A; Baylin S B; Gabrielson E
Methylation of the HIC-1 candidate tumor suppressor gene in human breast cancer.
Oncogene 1998;16(16):2159-64.
1998: Myöhänen S K; Baylin S B; Herman J G
Hypermethylation can selectively silence individual p16ink4A alleles in neoplasia.
Cancer research 1998;58(4):591-3.
1998: Ravi R K; Weber E; McMahon M; Williams J R; Baylin S; Mal A; Harter M L; Dillehay L E; Claudio P P; Giordano A; Nelkin B D; Mabry M
Activated Raf-1 causes growth arrest in human small cell lung cancer cells.
The Journal of clinical investigation 1998;101(1):153-9.
1998: Baylin S B; Herman J G; Graff J R; Vertino P M; Issa J P
Alterations in DNA methylation: a fundamental aspect of neoplasia.
Advances in cancer research 1998;72():141-96.
1997: Ferguson A T; Vertino P M; Spitzner J R; Baylin S B; Muller M T; Davidson N E
Role of estrogen receptor gene demethylation and DNA methyltransferase.DNA adduct formation in 5-aza-2'deoxycytidine-induced cytotoxicity in human breast cancer cells.
The Journal of biological chemistry 1997;272(51):32260-6.
1997: Thiagalingam A; Lengauer C; Baylin S B; Nelkin B D
RREB1, a ras responsive element binding protein, maps to human chromosome 6p25.
Genomics 1997;45(3):630-2.
1997: Yamashiro D J; Liu X G; Lee C P; Nakagawara A; Ikegaki N; McGregor L M; Baylin S B; Brodeur G M
Expression and function of Trk-C in favourable human neuroblastomas.
European journal of cancer (Oxford, England : 1990) 1997;33(12):2054-7.
1997: Baylin S B
Tying it all together: epigenetics, genetics, cell cycle, and cancer.
Science (New York, N.Y.) 1997;277(5334):1948-9.
1997: Ahuja N; Mohan A L; Li Q; Stolker J M; Herman J G; Hamilton S R; Baylin S B; Issa J P
Association between CpG island methylation and microsatellite instability in colorectal cancer.
Cancer research 1997;57(16):3370-4.
1997: Graff J R; Herman J G; Myöhänen S; Baylin S B; Vertino P M
Mapping patterns of CpG island methylation in normal and neoplastic cells implicates both upstream and downstream regions in de novo methylation.
The Journal of biological chemistry 1997;272(35):22322-9.
1997: Schutte M; Hruban R H; Geradts J; Maynard R; Hilgers W; Rabindran S K; Moskaluk C A; Hahn S A; Schwarte-Waldhoff I; Schmiegel W; Baylin S B; Kern S E; Herman J G
Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.
Cancer research 1997;57(15):3126-30.
1997: Chen H; Biel M A; Borges M W; Thiagalingam A; Nelkin B D; Baylin S B; Ball D W
Tissue-specific expression of human achaete-scute homologue-1 in neuroendocrine tumors: transcriptional regulation by dual inhibitory regions.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(6):677-86.
1997: Jarrard D F; Bova G S; Ewing C M; Pin S S; Nguyen S H; Baylin S B; Cairns P; Sidransky D; Herman J G; Isaacs W B
Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer.
Genes, chromosomes & cancer 1997;19(2):90-6.
1997: Chen H; Thiagalingam A; Chopra H; Borges M W; Feder J N; Nelkin B D; Baylin S B; Ball D W
Conservation of the Drosophila lateral inhibition pathway in human lung cancer: a hairy-related protein (HES-1) directly represses achaete-scute homolog-1 expression.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):5355-60.
1997: Kubota T; Das S; Christian S L; Baylin S B; Herman J G; Ledbetter D H
Methylation-specific PCR simplifies imprinting analysis.
Nature genetics 1997;16(1):16-7.
1997: Issa J P; Zehnbauer B A; Kaufmann S H; Biel M A; Baylin S B
HIC1 hypermethylation is a late event in hematopoietic neoplasms.
Cancer research 1997;57(9):1678-81.
1997: Borges M; Linnoila R I; van de Velde H J; Chen H; Nelkin B D; Mabry M; Baylin S B; Ball D W
An achaete-scute homologue essential for neuroendocrine differentiation in the lung.
Nature 1997;386(6627):852-5.
1997: Barr L F; Campbell S E; Baylin S B
Protein kinase C-beta 2 inhibits cycling and decreases c-myc-induced apoptosis in small cell lung cancer cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1997;8(4):381-92.
1997: Issa J P; Baylin S B; Herman J G
DNA methylation changes in hematologic malignancies: biologic and clinical implications.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1997;11 Suppl 1():S7-11.
1997: Herman J G; Civin C I; Issa J P; Collector M I; Sharkis S J; Baylin S B
Distinct patterns of inactivation of p15INK4B and p16INK4A characterize the major types of hematological malignancies.
Cancer research 1997;57(5):837-41.
1997: Swafford D S; Middleton S K; Palmisano W A; Nikula K J; Tesfaigzi J; Baylin S B; Herman J G; Belinsky S A
Frequent aberrant methylation of p16INK4a in primary rat lung tumors.
Molecular and cellular biology 1997;17(3):1366-74.
1996: Yoder J A; Yen R W; Vertino P M; Bestor T H; Baylin S B
New 5' regions of the murine and human genes for DNA (cytosine-5)-methyltransferase.
The Journal of biological chemistry 1996;271(49):31092-7.
1996: Issa J P; Vertino P M; Boehm C D; Newsham I F; Baylin S B
Switch from monoallelic to biallelic human IGF2 promoter methylation during aging and carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11757-62.
1996: Thiagalingam A; De Bustros A; Borges M; Jasti R; Compton D; Diamond L; Mabry M; Ball D W; Baylin S B; Nelkin B D
RREB-1, a novel zinc finger protein, is involved in the differentiation response to Ras in human medullary thyroid carcinomas.
Molecular and cellular biology 1996;16(10):5335-45.
1996: Barr L F; Campbell S E; Penno M B; Ball D W; Baylin S B
Cell-substratum interactions mediate oncogene-induced phenotype of lung cancer cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(9):1149-56.
1996: Herman J G; Graff J R; Myöhänen S; Nelkin B D; Baylin S B
Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9821-6.
1996: Vertino P M; Yen R W; Gao J; Baylin S B
De novo methylation of CpG island sequences in human fibroblasts overexpressing DNA (cytosine-5-)-methyltransferase.
Molecular and cellular biology 1996;16(8):4555-65.
1996: Chen H; Carson-Walter E B; Baylin S B; Nelkin B D; Ball D W
Differentiation of medullary thyroid cancer by C-Raf-1 silences expression of the neural transcription factor human achaete-scute homolog-1.
Surgery 1996;120(2):168-72; discussion 173.
1996: Issa J P; Baylin S B; Belinsky S A
Methylation of the estrogen receptor CpG island in lung tumors is related to the specific type of carcinogen exposure.
Cancer research 1996;56(16):3655-8.
1996: Morton R A; Watkins J J; Bova G S; Wales M M; Baylin S B; Isaacs W B
Hypermethylation of chromosome 17P locus D17S5 in human prostate tissue.
The Journal of urology 1996;156(2 Pt 1):512-6.
1996: Kuerbitz S J; Baylin S B
Retention of unmethylated CpG island alleles in human diploid fibroblast x fibrosarcoma hybrids expressing high levels of DNA methyltransferase.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1996;7(6):847-53.
1996: Lapidus R G; Ferguson A T; Ottaviano Y L; Parl F F; Smith H S; Weitzman S A; Baylin S B; Issa J P; Davidson N E
Methylation of estrogen and progesterone receptor gene 5' CpG islands correlates with lack of estrogen and progesterone receptor gene expression in breast tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(5):805-10.
1996: Belinsky S A; Nikula K J; Baylin S B; Issa J P
Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4045-50.
1996: Issa J P; Zehnbauer B A; Civin C I; Collector M I; Sharkis S J; Davidson N E; Kaufmann S H; Baylin S B
The estrogen receptor CpG island is methylated in most hematopoietic neoplasms.
Cancer research 1996;56(5):973-77.
1996: Issa J P; Baylin S B
Epigenetics and human disease.
Nature medicine 1996;2(3):281-2.
1996: Herman J G; Jen J; Merlo A; Baylin S B
Hypermethylation-associated inactivation indicates a tumor suppressor role for p15INK4B.
Cancer research 1996;56(4):722-7.
1996: Wu J; Herman J G; Wilson G; Lee R Y; Yen R W; Mabry M; de Bustros A; Nelkin B D; Baylin S B
Expression of prokaryotic HhaI DNA methyltransferase is transforming and lethal to NIH 3T3 cells.
Cancer research 1996;56(3):616-22.
1995: Belinsky S A; Nikula K J; Baylin S B; Issa J P
A microassay for measuring cytosine DNA methyltransferase activity during tumor progression.
Toxicology letters 1995;82-83():335-40.
1995: Graff J R; Herman J G; Lapidus R G; Chopra H; Xu R; Jarrard D F; Isaacs W B; Pitha P M; Davidson N E; Baylin S B
E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas.
Cancer research 1995;55(22):5195-9.
1995: Herman J G; Merlo A; Mao L; Lapidus R G; Issa J P; Davidson N E; Sidransky D; Baylin S B
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.
Cancer research 1995;55(20):4525-30.
1995: Merlo A; Herman J G; Mao L; Lee D J; Gabrielson E; Burger P C; Baylin S B; Sidransky D
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Nature medicine 1995;1(7):686-92.
1995: Wales M M; Biel M A; el Deiry W; Nelkin B D; Issa J P; Cavenee W K; Kuerbitz S J; Baylin S B
p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3.
Nature medicine 1995;1(6):570-7.
1995: Ferguson A T; Lapidus R G; Baylin S B; Davidson N E
Demethylation of the estrogen receptor gene in estrogen receptor-negative breast cancer cells can reactivate estrogen receptor gene expression.
Cancer research 1995;55(11):2279-83.
1995: Carson E B; McMahon M; Baylin S B; Nelkin B D
Ret gene silencing is associated with Raf-1-induced medullary thyroid carcinoma cell differentiation.
Cancer research 1995;55(10):2048-52.
1994: Vertino P M; Issa J P; Pereira-Smith O M; Baylin S B
Stabilization of DNA methyltransferase levels and CpG island hypermethylation precede SV40-induced immortalization of human fibroblasts.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(12):1395-402.
1994: Blaugrund J E; Johns M M; Eby Y J; Ball D W; Baylin S B; Hruban R H; Sidransky D
RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer.
Human molecular genetics 1994;3(10):1895-7.
1994: Issa J P; Ottaviano Y L; Celano P; Hamilton S R; Davidson N E; Baylin S B
Methylation of the oestrogen receptor CpG island links ageing and neoplasia in human colon.
Nature genetics 1994;7(4):536-40.
1994: McGregor L M; Baylin S B; Griffin C A; Hawkins A L; Nelkin B D
Molecular cloning of the cDNA for human TrkC (NTRK3), chromosomal assignment, and evidence for a splice variant.
Genomics 1994;22(2):267-72.
1994: Ottaviano Y L; Issa J P; Parl F F; Smith H S; Baylin S B; Davidson N E
Methylation of the estrogen receptor gene CpG island marks loss of estrogen receptor expression in human breast cancer cells.
Cancer research 1994;54(10):2552-5.
1994: Merlo A; Gabrielson E; Mabry M; Vollmer R; Baylin S B; Sidransky D
Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer.
Cancer research 1994;54(9):2322-6.
1994: Merlo A; Mabry M; Gabrielson E; Vollmer R; Baylin S B; Sidransky D
Frequent microsatellite instability in primary small cell lung cancer.
Cancer research 1994;54(8):2098-101.
1994: Nelkin B D; Ball D W; Baylin S B
Molecular abnormalities in tumors associated with multiple endocrine neoplasia type 2.
Endocrinology and metabolism clinics of North America 1994;23(1):187-213.
1994: Penno M B; August J T; Baylin S B; Mabry M; Linnoila R I; Lee V S; Croteau D; Yang X L; Rosada C
Expression of CD44 in human lung tumors.
Cancer research 1994;54(5):1381-7.
1994: Wu L T; Averbuch S D; Ball D W; de Bustros A; Baylin S B; McGuire W P
Treatment of advanced medullary thyroid carcinoma with a combination of cyclophosphamide, vincristine, and dacarbazine.
Cancer 1994;73(2):432-6.
1993: Udelsman R; Ball D; Baylin S B; Wong C Y; Osterman F A; Sostre S
Preoperative localization of occult medullary carcinoma of the thyroid gland with single-photon emission tomography dimercaptosuccinic acid.
Surgery 1993;114(6):1083-9.
1993: Wu J; Issa J P; Herman J; Bassett D E; Nelkin B D; Baylin S B
Expression of an exogenous eukaryotic DNA methyltransferase gene induces transformation of NIH 3T3 cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(19):8891-5.
1993: Issa J P; Vertino P M; Wu J; Sazawal S; Celano P; Nelkin B D; Hamilton S R; Baylin S B
Increased cytosine DNA-methyltransferase activity during colon cancer progression.
Journal of the National Cancer Institute 1993;85(15):1235-40.
1993: Nelkin B D; Baylin S B
Ret oncogene responsible for MEN2A.
Current biology : CB 1993;3(7):477-80.
1993: Makos M; Nelkin B D; Reiter R E; Gnarra J R; Brooks J; Isaacs W; Linehan M; Baylin S B
Regional DNA hypermethylation at D17S5 precedes 17p structural changes in the progression of renal tumors.
Cancer research 1993;53(12):2719-22.
1993: Ball D W; Azzoli C G; Baylin S B; Chi D; Dou S; Donis-Keller H; Cumaraswamy A; Borges M; Nelkin B D
Identification of a human achaete-scute homolog highly expressed in neuroendocrine tumors.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(12):5648-52.
1993: Makos M; Nelkin B D; Chazin V R; Cavenee W K; Brodeur G M; Baylin S B
DNA hypermethylation is associated with 17p allelic loss in neural tumors.
Cancer research 1993;53(12):2715-8.
1993: Lairmore T C; Ball D W; Baylin S B; Wells S A
Management of pheochromocytomas in patients with multiple endocrine neoplasia type 2 syndromes.
Annals of surgery 1993;217(6):595-601; discussion 601-3.
1993: Vertino P M; Spillare E A; Harris C C; Baylin S B
Altered chromosomal methylation patterns accompany oncogene-induced transformation of human bronchial epithelial cells.
Cancer research 1993;53(7):1684-9.
1993: Baylin S B; de Bustros A C; Ball D W; Nelkin B D
Pathobiology of the C-cells.
Monographs in pathology 1993;(35):63-71.
1992: Fukuhara T; Hooper W C; Baylin S B; Benson J; Pruckler J; Olson A C; Evatt B L; Vogler W R
Use of the polymerase chain reaction to detect hypermethylation in the calcitonin gene. A new, sensitive approach to monitor tumor cells in acute myelogenous leukemia.
Leukemia research 1992;16(10):1031-40.
1992: Celano P; Berchtold C M; Kizer D L; Weeraratna A; Nelkin B D; Baylin S B; Casero R A
Characterization of an endogenous RNA transcript with homology to the antisense strand of the human c-myc gene.
The Journal of biological chemistry 1992;267(21):15092-6.
1992: Yen R W; Vertino P M; Nelkin B D; Yu J J; el-Deiry W; Cumaraswamy A; Lennon G G; Trask B J; Celano P; Baylin S B
Isolation and characterization of the cDNA encoding human DNA methyltransferase.
Nucleic acids research 1992;20(9):2287-91.
1992: Mabry M; Moody T W; Baylin S B
Preclinical research in early lung cancer: breakout group report.
Cancer research 1992;52(9 Suppl):2764s-2765s.
1992: Baylin S B
Abnormal regional hypermethylation in cancer cells.
AIDS research and human retroviruses 1992;8(5):811-20.
1992: Makos M; Nelkin B D; Lerman M I; Latif F; Zbar B; Baylin S B
Distinct hypermethylation patterns occur at altered chromosome loci in human lung and colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1929-33.
1992: Moley J F; Brother M B; Fong C T; White P S; Baylin S B; Nelkin B; Wells S A; Brodeur G M
Consistent association of 1p loss of heterozygosity with pheochromocytomas from patients with multiple endocrine neoplasia type 2 syndromes.
Cancer research 1992;52(4):770-4.
1992: Ball D W; Compton D; Nelkin B D; Baylin S B; de Bustros A
Human calcitonin gene regulation by helix-loop-helix recognition sequences.
Nucleic acids research 1992;20(1):117-23.
1991: Baylin S B; Makos M; Wu J J; Yen R W; de Bustros A; Vertino P; Nelkin B D
Abnormal patterns of DNA methylation in human neoplasia: potential consequences for tumor progression.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(10):383-90.
1991: Barr L F; Mabry M; Nelkin B D; Tyler G; May W S; Baylin S B
c-myc gene-induced alterations in protein kinase C expression: a possible mechanism facilitating myc-ras gene complementation.
Cancer research 1991;51(20):5514-9.
1991: Nelkin B D; Przepiorka D; Burke P J; Thomas E D; Baylin S B
Abnormal methylation of the calcitonin gene marks progression of chronic myelogenous leukemia.
Blood 1991;77(11):2431-4.
1991: el-Deiry W S; Nelkin B D; Celano P; Yen R W; Falco J P; Hamilton S R; Baylin S B
High expression of the DNA methyltransferase gene characterizes human neoplastic cells and progression stages of colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3470-4.
1991: Mabry M; Nelkin B D; Falco J P; Barr L F; Baylin S B
Transitions between lung cancer phenotypes--implications for tumor progression.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1991;3(2):53-8.
1990: Nelkin B D; Borges M; Mabry M; Baylin S B
Transcription factor levels in medullary thyroid carcinoma cells differentiated by Harvey ras oncogene: c-jun is increased.
Biochemical and biophysical research communications 1990;170(1):140-6.
1990: Falco J P; Baylin S B; Lupu R; Borges M; Nelkin B D; Jasti R K; Davidson N E; Mabry M
v-rasH induces non-small cell phenotype, with associated growth factors and receptors, in a small cell lung cancer cell line.
The Journal of clinical investigation 1990;85(6):1740-5.
1990: Brauch H; Latif F; Baylin S; Nelkin B D; Hosoe S; Daniel L; Glenn G; Danko I; Bradley W E; Orcutt M L
MspI and DraI polymorphisms at the ERBA beta locus on chromosome 3p.
Nucleic acids research 1990;18(9):2833.
1990: de Bustros A; Lee R Y; Compton D; Tsong T Y; Baylin S B; Nelkin B D
Differential utilization of calcitonin gene regulatory DNA sequences in cultured lines of medullary thyroid carcinoma and small-cell lung carcinoma.
Molecular and cellular biology 1990;10(4):1773-8.
1990: Baylin S B
"APUD" cells fact and fiction.
Trends in endocrinology and metabolism: TEM 1990;1(4):198-204.
1989: Nelkin B D; Chen K Y; de Bustros A; Roos B A; Baylin S B
Changes in calcitonin gene RNA processing during growth of a human medullary thyroid carcinoma cell line.
Cancer research 1989;49(24 Pt 1):6949-52.
1989: Nigro J M; Baker S J; Preisinger A C; Jessup J M; Hostetter R; Cleary K; Bigner S H; Davidson N; Baylin S; Devilee P
Mutations in the p53 gene occur in diverse human tumour types.
Nature 1989;342(6250):705-8.
1989: Baylin S B
Neuroendocrine differentiation: a prognostic feature of non-small-cell lung cancer?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1989;7(10):1375-6.
1989: Nelkin B D; Nakamura Y; White R W; de Bustros A C; Herman J; Wells S A; Baylin S B
Low incidence of loss of chromosome 10 in sporadic and hereditary human medullary thyroid carcinoma.
Cancer research 1989;49(15):4114-9.
1989: Silverman A L; Park J G; Hamilton S R; Gazdar A F; Luk G D; Baylin S B
Abnormal methylation of the calcitonin gene in human colonic neoplasms.
Cancer research 1989;49(13):3468-73.
1989: Mabry M; Nakagawa T; Baylin S; Pettengill O; Sorenson G; Nelkin B
Insertion of the v-Ha-ras oncogene induces differentiation of calcitonin-producing human small cell lung cancer.
The Journal of clinical investigation 1989;84(1):194-9.
1989: Hausheer F H; Rao S N; Gamcsik M P; Kollman P A; Colvin O M; Saxe J D; Nelkin B D; McLennan I J; Barnett G; Baylin S B
Computational analysis of structural and energetic consequences of DNA methylation.
Carcinogenesis 1989;10(6):1131-7.
1989: Nelkin B D; de Bustros A C; Mabry M; Baylin S B
The molecular biology of medullary thyroid carcinoma. A model for cancer development and progression.
JAMA : the journal of the American Medical Association 1989;261(21):3130-5.
1989: Celano P; Baylin S B; Casero R A
Polyamines differentially modulate the transcription of growth-associated genes in human colon carcinoma cells.
The Journal of biological chemistry 1989;264(15):8922-7.
1989: Casero R A; Ervin S J; Celano P; Baylin S B; Bergeron R J
Differential response to treatment with the bis(ethyl)polyamine analogues between human small cell lung carcinoma and undifferentiated large cell lung carcinoma in culture.
Cancer research 1989;49(3):639-43.
1988: Tockman M S; Gupta P K; Myers J D; Frost J K; Baylin S B; Gold E B; Chase A M; Wilkinson P H; Mulshine J L
Sensitive and specific monoclonal antibody recognition of human lung cancer antigen on preserved sputum cells: a new approach to early lung cancer detection.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1988;6(11):1685-93.
1988: Mabry M; Nakagawa T; Nelkin B D; McDowell E; Gesell M; Eggleston J C; Casero R A; Baylin S B
v-Ha-ras oncogene insertion: a model for tumor progression of human small cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(17):6523-7.
1988: de Bustros A; Nelkin B D; Silverman A; Ehrlich G; Poiesz B; Baylin S B
The short arm of chromosome 11 is a "hot spot" for hypermethylation in human neoplasia.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5693-7.
1988: Nakagawa T; Nelkin B D; Baylin S B; de Bustros A
Transcriptional and posttranscriptional modulation of calcitonin gene expression by sodium n-butyrate in cultured human medullary thyroid carcinoma.
Cancer research 1988;48(8):2096-100.
1988: Celano P; Baylin S B; Giardiello F M; Nelkin B D; Casero R A
Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.
The Journal of biological chemistry 1988;263(12):5491-4.
1987: Baylin S B; Fearon E R; Vogelstein B; de Bustros A; Sharkis S J; Burke P J; Staal S P; Nelkin B D
Hypermethylation of the 5' region of the calcitonin gene is a property of human lymphoid and acute myeloid malignancies.
Blood 1987;70(2):412-7.
1987: Nakagawa T; Mabry M; de Bustros A; Ihle J N; Nelkin B D; Baylin S B
Introduction of v-Ha-ras oncogene induces differentiation of cultured human medullary thyroid carcinoma cells.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5923-7.
1987: Casero R A; Go B; Theiss H W; Smith J; Baylin S B; Luk G D
Cytotoxic response of the relatively difluoromethylornithine-resistant human lung tumor cell line NCI H157 to the polyamine analogue N1,N8-bis(ethyl)spermidine.
Cancer research 1987;47(15):3964-7.
1987: Helman L J; Thiele C J; Linehan W M; Nelkin B D; Baylin S B; Israel M A
Molecular markers of neuroendocrine development and evidence of environmental regulation.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2336-9.
1987: Tanaka K; Baylin S B; Nelkin B D; Testa J R
Cytogenetic studies of a human medullary thyroid carcinoma cell line.
Cancer genetics and cytogenetics 1987;25(1):27-35.
1987: Griffin C A; Slavik M; Chien S C; Hermann J; Thompson G; Blanc O; Luk G D; Baylin S B; Abeloff M D
Phase I trial and pharmacokinetic study of intravenous and oral alpha-difluoromethylornithine.
Investigational new drugs 1987;5(2):177-86.
1986: Wong A J; Ruppert J M; Eggleston J; Hamilton S R; Baylin S B; Vogelstein B
Gene amplification of c-myc and N-myc in small cell carcinoma of the lung.
Science (New York, N.Y.) 1986;233(4762):461-4.
1986: Abeloff M D; Rosen S T; Luk G D; Baylin S B; Zeltzman M; Sjoerdsma A
Phase II trials of alpha-difluoromethylornithine, an inhibitor of polyamine synthesis, in advanced small cell lung cancer and colon cancer.
Cancer treatment reports 1986;70(7):843-5.
1986: Ruppert J M; Eggleston J C; deBustros A; Baylin S B
Disseminated calcitonin-poor medullary thyroid carcinoma in a patient with calcitonin-rich primary tumor.
The American journal of surgical pathology 1986;10(7):513-8.
1986: deBustros A; Baylin S B; Levine M A; Nelkin B D
Cyclic AMP and phorbol esters separately induce growth inhibition, calcitonin secretion, and calcitonin gene transcription in cultured human medullary thyroid carcinoma.
The Journal of biological chemistry 1986;261(17):8036-41.
1986: Baylin S B; Höppener J W; de Bustros A; Steenbergh P H; Lips C J; Nelkin B D
DNA methylation patterns of the calcitonin gene in human lung cancers and lymphomas.
Cancer research 1986;46(6):2917-22.
1986: Farndon J R; Leight G S; Dilley W G; Baylin S B; Smallridge R C; Harrison T S; Wells S A
Familial medullary thyroid carcinoma without associated endocrinopathies: a distinct clinical entity.
The British journal of surgery 1986;73(4):278-81.
1986: Luk G D; Abeloff M D; McCann P P; Sjoerdsma A; Baylin S B
Long-term maintenance therapy of established human small cell variant lung carcinoma implants in athymic mice with a cyclic regimen of difluoromethylornithine.
Cancer research 1986;46(4 Pt 1):1849-53.
1986: Luk G D; Baylin S B
Anchorage dependency effects on difluoromethylornithine cytotoxicity in human lung carcinoma cells.
Cancer research 1986;46(4 Pt 1):1844-8.
1986: Casero R A; Baylin S B; Nelkin B D; Luk G D
Human lung tumor sensitivity to difluoromethylornithine as related to ornithine decarboxylase messenger RNA levels.
Biochemical and biophysical research communications 1986;134(2):572-9.
1985: Wand G S; Ney R L; Baylin S; Eipper B; Mains R E
Characterization of a peptide alpha-amidation activity in human plasma and tissues.
Metabolism: clinical and experimental 1985;34(11):1044-52.
1985: Gazdar A F; Bunn P A; Minna J D; Baylin S B
Origin of human small cell lung cancer.
Science (New York, N.Y.) 1985;229(4714):679-80.
1985: Wells S A; Dilley W G; Farndon J A; Leight G S; Baylin S B
Early diagnosis and treatment of medullary thyroid carcinoma.
Archives of internal medicine 1985;145(7):1248-52.
1985: Robinson-White A; Baylin S B; Olivecrona T; Beaven M A
Binding of diamine oxidase activity to rat and guinea pig microvascular endothelial cells. Comparisons with lipoprotein lipase binding.
The Journal of clinical investigation 1985;76(1):93-100.
1985: Gupta P K; Myers J D; Baylin S B; Mulshine J L; Cuttitta F; Gazdar A F
Improved antigen detection in ethanol-fixed cytologic specimens. A modified avidin-biotin-peroxidase complex (ABC) method.
Diagnostic cytopathology 1985;1(2):133-6.
1985: de Bustros A; Baylin S B
Hormone production by tumours: biological and clinical aspects.
Clinics in endocrinology and metabolism 1985;14(1):221-56.
1985: Luk G D; Baylin S B
Polyamines in biology and medicine.
The Western journal of medicine 1985;142(1):88-90.
1985: de Bustros A; Baylin S B; Berger C L; Roos B A; Leong S S; Nelkin B D
Phorbol esters increase calcitonin gene transcription and decrease c-myc mRNA levels in cultured human medullary thyroid carcinoma.
The Journal of biological chemistry 1985;260(1):98-104.
1985: Griffin C A; Baylin S B
Expression of the c-myb oncogene in human small cell lung carcinoma.
Cancer research 1985;45(1):272-5.
1985: Griffin C A; Baylin S B
Oncogene expression in human small cell lung carcinoma.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1985;99():237-45.
1985: Höppener J W; Steenbergh P H; Zandberg J; Geurts van Kessel A H; Baylin S B; Nelkin B D; Jansz H S; Lips C J
The second human calcitonin/CGRP gene is located on chromosome 11.
Human genetics 1985;70(3):259-63.
1984: Yang P; Baylin S B; Luk G D
Polyamines and intestinal growth: absolute requirement for ODC activity in adaptation during lactation.
The American journal of physiology 1984;247(5 Pt 1):G553-7.
1984: Luk G D; Baylin S B
Inhibition of intestinal epithelial DNA synthesis and adaptive hyperplasia after jejunectomy in the rat by suppression of polyamine biosynthesis.
The Journal of clinical investigation 1984;74(3):698-704.
1984: Nelkin B D; Rosenfeld K I; de Bustros A; Leong S S; Roos B A; Baylin S B
Structure and expression of a gene encoding human calcitonin and calcitonin gene related peptide.
Biochemical and biophysical research communications 1984;123(2):648-55.
1984: Berger C L; de Bustros A; Roos B A; Leong S S; Mendelsohn G; Gesell M S; Baylin S B
Human medullary thyroid carcinoma in culture provides a model relating growth dynamics, endocrine cell differentiation, and tumor progression.
The Journal of clinical endocrinology and metabolism 1984;59(2):338-43.
1984: Mendelsohn G; Wells S A; Baylin S B
Relationship of tissue carcinoembryonic antigen and calcitonin to tumor virulence in medullary thyroid carcinoma. An immunohistochemical study in early, localized, and virulent disseminated stages of disease.
Cancer 1984;54(4):657-62.
1984: Luk G D; Baylin S B
Ornithine decarboxylase as a biologic marker in familial colonic polyposis.
The New England journal of medicine 1984;311(2):80-3.
1984: Przepiorka D; Baylin S B; McBride O W; Testa J R; de Bustros A; Nelkin B D
The human calcitonin gene is located on the short arm of chromosome 11.
Biochemical and biophysical research communications 1984;120(2):493-9.
1984: Abeloff M D; Slavik M; Luk G D; Griffin C A; Hermann J; Blanc O; Sjoerdsma A; Baylin S B
Phase I trial and pharmacokinetic studies of alpha-difluoromethylornithine--an inhibitor of polyamine biosynthesis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1984;2(2):124-30.
1984: Mendelsohn G; Baylin S B
Ectopic hormone production--biological and clinical implications.
Progress in clinical and biological research 1984;142():291-316.
1983: Maneckjee R; Baylin S B
Use of radiolabeled monofluoromethyl-Dopa to define the subunit structure of human L-Dopa decarboxylase.
Biochemistry 1983;22(26):6058-63.
1983: Luk G D; Baylin S B
Polyamines and intestinal growth--increased polyamine biosynthesis after jejunectomy.
The American journal of physiology 1983;245(5 Pt 1):G656-60.
1983: Luk G D; Abeloff M D; Griffin C A; Baylin S B
Successful treatment with DL-alpha-difluoromethylornithine in established human small cell variant lung carcinoma implants in athymic mice.
Cancer research 1983;43(9):4239-43.
1983: Luk G D; Sharkis S J; Abeloff M D; McCann P P; Sjoerdsma A; Baylin S B
Polyamine biosynthesis is required for the maintenance of peripheral blood cell elements in the rat.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(16):5090-3.
1983: Feinberg A P; Vogelstein B; Droller M J; Baylin S B; Nelkin B D
Mutation affecting the 12th amino acid of the c-Ha-ras oncogene product occurs infrequently in human cancer.
Science (New York, N.Y.) 1983;220(4602):1175-7.
1983: Goodwin G; Shaper J H; Abeloff M D; Mendelsohn G; Baylin S B
Analysis of cell surface proteins delineates a differentiation pathway linking endocrine and nonendocrine human lung cancers.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(12):3807-11.
1983: Luk G D; Bayless T M; Baylin S B
Plasma postheparin diamine oxidase. Sensitive provocative test for quantitating length of acute intestinal mucosal injury in the rat.
The Journal of clinical investigation 1983;71(5):1308-15.
1983: Roos B A; Huber M B; Birnbaum R S; Aron D C; Lindall A W; Lips K; Baylin S B
Medullary thyroid carcinomas secrete a noncalcitonin peptide corresponding to the carboxyl-terminal region of preprocalcitonin.
The Journal of clinical endocrinology and metabolism 1983;56(4):802-7.
1983: Bernal S D; Baylin S B; Shaper J H; Gazdar A F; Chen L B
Cytoskeleton-associated proteins of human lung cancer cells.
Cancer research 1983;43(4):1798-808.
1983: Bernal S; Thompson R; Gilbert F; Baylin S B
In vitro and in vivo growth characteristics of two different cell populations in an established line of human neuroblastoma.
Cancer research 1983;43(3):1256-60.
1983: Sharkis S J; Luk G D; Collector M I; McCann P P; Baylin S B; Sensenbrenner L L
Regulation of hematopoiesis II: the role of polyamine inhibition on helper or suppressor influences of the thymus.
Blood 1983;61(3):604-7.
1983: Oie H K; Gazdar A F; Minna J D; Weir G C; Baylin S B
Clonal analysis of insulin and somatostatin secretion and L-dopa decarboxylase expression by a rat islet cell tumor.
Endocrinology 1983;112(3):1070-5.
1983: Francis J; Thompson R; Bernal S D; Luk G D; Baylin S B
Effects of dibutyryl cyclic adenosine 3':5'-monophosphate on the growth of cultured human small-cell lung carcinoma and the specific cellular activity of L-dopa decarboxylase.
Cancer research 1983;43(2):639-45.
1983: Baylin S B; Jackson R H; Lennarz W; Shaper J H
The spectrum of human lung cancer cells in culture: a potential model for studying molecular determinants of tumor progression and metastasis.
Symposium on Fundamental Cancer Research 1983;36():281-91.
1982: Baylin S B; Mendelsohn G
Time-dependent changes in human tumors: implications for diagnosis and clinical behavior.
Seminars in oncology 1982;9(4):504-12.
1982: Wells S A; Baylin S B; Johnsrude I S; Harrington D P; Mendelsohn G; Ontjes D J; Cooper C W
Thyroid venous catheterization in the early diagnosis of familial medullary thyroid carcinoma.
Annals of surgery 1982;196(5):505-11.
1982: Baylin S B; Jackson R D; Goodwin G; Gazdar A F
Neuroendocrine-related biochemistry in the spectrum of human lung cancers.
Experimental lung research 1982;3(3-4):209-23.
1982: Luk G D; Goodwin G; Gazdar A F; Baylin S B
Growth-inhibitory effects of DL-alpha-difluoromethylornithine in the spectrum of human lung carcinoma cells in culture.
Cancer research 1982;42(8):3070-3.
1982: Baylin S B; Gazdar A F; Minna J D; Bernal S D; Shaper J H
A unique cell-surface protein phenotype distinguishes human small-cell from non-small-cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(15):4650-4.
1982: Wells S A; Baylin S B; Leight G S; Dale J K; Dilley W G; Farndon J R
The importance of early diagnosis in patients with hereditary medullary thyroid carcinoma.
Annals of surgery 1982;195(5):595-9.
1982: Luk G D; Civin C I; Weissman R M; Baylin S B
Ornithine decarboxylase: essential in proliferation but not differentiation of human promyelocytic leukemia cells.
Science (New York, N.Y.) 1982;216(4541):75-7.
1982: Goodwin G; Baylin S B
Relationships between neuroendocrine differentiation and sensitivity to gamma-radiation in culture line OH-1 of human small cell lung carcinoma.
Cancer research 1982;42(4):1361-7.
1982: Lippman S M; Mendelsohn G; Trump D L; Wells S A; Baylin S B
The prognostic and biological significance of cellular heterogeneity in medullary thyroid carcinoma: a study of calcitonin, L-dopa decarboxylase, and histaminase.
The Journal of clinical endocrinology and metabolism 1982;54(2):233-40.
1981: Abeloff M D; Trump D L; Baylin S B
Ectopic adrenocorticotrophic (ACTH) syndrome and small cell carcinoma of the lung-assessment of clinical implications in patients on combination chemotherapy.
Cancer 1981;48(5):1082-7.
1981: Baylin S B; Wieman K C; O'Neil J A; Roos B A
Multiple forms of human tumor calcitonin demonstrated by denaturing polyacrylamide gel electrophoresis and lectin affinity chromatography.
The Journal of clinical endocrinology and metabolism 1981;53(3):489-97.
1981: Berger C L; Goodwin G; Mendelsohn G; Eggleston J C; Abeloff M D; Aisner S; Baylin S B
Endocrine-related biochemistry in the spectrum of human lung carcinoma.
The Journal of clinical endocrinology and metabolism 1981;53(2):422-9.
1981: Baylin S B; Wells S A
Management of hereditary medullary thyroid carcinoma.
Clinics in endocrinology and metabolism 1981;10(2):367-78.
1981: Bigner S H; Cox E B; Mendelsohn G; Baylin S B; Wells S A; Eggleston J C
Medullary carcinoma of the thyroid in the multiple endocrine neoplasia IIA syndrome.
The American journal of surgical pathology 1981;5(5):459-72.
1981: Gazdar A F; Zweig M H; Carney D N; Van Steirteghen A C; Baylin S B; Minna J D
Levels of creatine kinase and its BB isoenzyme in lung cancer specimens and cultures.
Cancer research 1981;41(7):2773-7.
1981: Luk G D; Vaughan W P; Burke P J; Baylin S B
Diamine oxidase as a plasma marker of rat intestinal mucosal injury and regeneration after administration of 1-beta-D-arabinofuranosylcytosine.
Cancer research 1981;41(6):2334-7.
1981: Luk G D; Goodwin G; Marton L J; Baylin S B
Polyamines are necessary for the survival of human small-cell lung carcinoma in culture.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(4):2355-8.
1980: Lux G D; Marton L J; Baylin S B
Ornithine decarboxylase is important in intestinal mucosal maturation and recovery from injury in rats.
Science (New York, N.Y.) 1980;210(4466):195-8.
1980: Gazdar A F; Carney D N; Russell E K; Sims H L; Baylin S B; Bunn P A; Guccion J G; Minna J D
Establishment of continuous, clonable cultures of small-cell carcinoma of lung which have amine precursor uptake and decarboxylation cell properties.
Cancer research 1980;40(10):3502-7.
1980: Mendelsohn G; Baylin S B; Bigner S H; Wells S A; Eggleston J C
Anaplastic variants of medullary thyroid carcinoma: a light-microscopic and immunohistochemical study.
The American journal of surgical pathology 1980;4(4):333-41.
1980: Baylin S B; Rosenstein B J; Marton L J; Lockwood D H
Age-related abnormalities of circulating polyamines and diamine oxidase activity in cystic fibrosis heterozygotes and homozygotes.
Pediatric research 1980;14(8):921-5.
1980: Luk G D; Bayless T M; Baylin S B
Diamine oxidase (histaminase). A circulating marker for rat intestinal mucosal maturation and integrity.
The Journal of clinical investigation 1980;66(1):66-70.
1980: Baylin S B; Abeloff M D; Goodwin G; Carney D N; Gazdar A F
Activities of L-dopa decarboxylase and diamine oxidase (histaminase) in human lung cancers and decarboxylase as a marker for small (oat) cell cancer in cell culture.
Cancer research 1980;40(6):1990-4.
1980: Ettinger D S; Rosenshein N B; Parmley T H; Mendelsohn G; Baylin S B
Tumor cell origin of histaminase activity in ascites fluid from patients with ovarian carcinoma.
Cancer 1980;45(10):2568-72.
1980: Roos B A; Lindall A W; Baylin S B; O'Neil J A; Frelinger A L; Birnbaum R S; Lambert P W
Plasma immunoreactive calcitonin in lung cancer.
The Journal of clinical endocrinology and metabolism 1980;50(4):659-66.
1980: Mendelsohn G; Baylin S B; Eggleston J C
Relationship of metastatic medullary thyroid carcinoma to calcitonin content of pheochromocytomas: an immunohistochemical study.
Cancer 1980;45(3):498-502.
1980: Baylin S B; Mendelsohn G
Ectopic (inappropriate) hormone production by tumors: mechanisms involved and the biological and clinical implications.
Endocrine reviews 1980;1(1):45-77.
1979: Baylin S B; Mendelsohn G; Weisburger W R; Gann D S; Eggleston J C
Levels of histaminase and L-DOPA decarboxylase activity in the transition from C-cell hyperplasia to familial medullary thyroid carcinoma.
Cancer 1979;44(4):1315-21.
1979: Trump D L; Mendelsohn G; Baylin S B
Discordance between plasma calcitonin and tumor-cell mass in medullary thyroid carcinoma.
The New England journal of medicine 1979;301(5):253-5.
1979: Mendelsohn G; Eggleston J C; Olson J L; Said S I; Baylin S B
Vasoactive intestinal peptide and its relationship to ganglion cell differentiation in neuroblastic tumors.
Laboratory investigation; a journal of technical methods and pathology 1979;41(2):144-9.
1979: Mendelsohn G; D'Agostino R; Eggleston J C; Baylin S B
Distribution of beta-endorphin immunoreactivity in normal human pituitary.
The Journal of clinical investigation 1979;63(6):1297-301.
1979: Hutcheon D F; Bayless T M; Cameron J L; Baylin S B
Hormone-mediated watery diarrhea in a family with multiple endocrine neoplasms.
Annals of internal medicine 1979;90(6):932-4.
1979: Abeloff M D; Eggleston J C; Mendelsohn G; Ettinger D S; Baylin S B
Changes in morphologic and biochemical characteristics of small cell carcinoma of the lung. A clinicopathologic study.
The American journal of medicine 1979;66(5):757-64.
1979: Baylin S B; Hsu T H; Stevens S A; Kallman C H; Trump D L; Beaven M A
The effects of L-dopa on in vitro and in vivo calcitonin release from medullary thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 1979;48(3):408-14.
1979: Cox C E; VanVickle J; Froome L C; Mendelsohn G; Baylin S B; Wells S A
Carcinoembryonic antigen and calcitonin as markers of malignancy in medullary thyroid carcinoma.
Surgical forum 1979;30():120-1.
1979: Roos B A; Lindall A W; Baylin S B; O'Neil J; Frelinger A L; Birnbaum R S; Lambert P W
Plasma immunoreactive calcitonin in lung cancer.
Endocrine research communications 1979;6(2):169-90.
1978: Wells S A; Baylin S B; Gann D S; Farrell R E; Dilley W G; Preissig S H; Linehan W M; Cooper C W
Medullary thyroid carcinoma: relationship of method of diagnosis to pathologic staging.
Annals of surgery 1978;188(3):377-83.
1978: Wells S A; Baylin S B; Linehan W M; Farrell R E; Cox E B; Cooper C W
Provocative agents and the diagnosis of medullary carcinoma of the thyroid gland.
Annals of surgery 1978;188(2):139-41.
1978: Mendelsohn G; Eggleston J C; Weisburger W R; Gann D S; Baylin S B
Calcitonin and histaminase in C-cell hyperplasia and medullary thyroid carcinoma. A light microscopic and immunohistochemical study.
The American journal of pathology 1978;92(1):35-52.
1978: Baylin S B; Stevens S A; Shakir K M
Association of diamine oxidase and ornithine decarboxylase with maturing cells in rapidly proliferating epithelium.
Biochimica et biophysica acta 1978;541(3):415-9.
1978: Baylin S B; Weisburger W R; Eggleston J C; Mendelsohn G; Beaven M A; Abeloff M D; Ettinger D S
Variable content of histaminase, L-dopa decarboxylase and calcitonin in small-cell carcinoma of the lung. Biologic and clinical implications.
The New England journal of medicine 1978;299(3):105-10.
1978: Ettinger D S; Baylin S B; Minaberry D; Abeloff M D; Mellits E D
Response of plasma histaminase activity to heparin in normal subjects and in patients with small cell carcinoma of the lung.
Journal of the National Cancer Institute 1978;60(6):1239-42.
1978: Weisburger W R; Mendelsohn G; Eggleston J C; Baylin S B
Immunohistochemical localization of histaminase (diamine oxidase) in decidual cells of human placenta.
Laboratory investigation; a journal of technical methods and pathology 1978;38(6):703-6.
1978: Baylin S B
The multiple endocrine neoplasia syndromes: implications for the study of inherited tumors.
Seminars in oncology 1978;5(1):35-45.
1978: Baylin S B; Hsu S H; Gann D S; Smallridge R C; Wells S A
Inherited medullary thyroid carcinoma: a final monoclonal mutation in one of multiple clones of susceptible cells.
Science (New York, N.Y.) 1978;199(4327):429-31.
1977: Shakir K M; Margolis S; Baylin S B
Localization of histamine (diamine oxidase) in rat small intestinal mucosa: site of release by heparin.
Biochemical pharmacology 1977;26(24):2343-7.
1977: Baylin S B; Bailey A L; Hsu T H; Foster G V
Degradation of human calcitonin in human plasmas.
Metabolism: clinical and experimental 1977;26(12):1345-54.
1977: Trump D L; Livingston J N; Baylin S B
Watery diarrhea syndrome in an adult with ganglioneuroma-pheochromocytoma: identification of vasoactive intestinal peptide, calcitonin, and catecholamines and assessment of their biologic activity.
Cancer 1977;40(4):1526-32.
1977: Kwiterovich P O; Farah J R; Brown W V; Bachorik P S; Baylin S B; Neill C A
The clinical, biochemical, and familial presentation of type V hyperlipoproteinemia in childhood.
Pediatrics 1977;59(4):513-25.
1977: Baylin S B
Histaminase (diamine oxidase) activity in human tumors: an expression of a mature genome.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(3):883-7.
1976: Abeloff M D; Ettinger D S; Baylin S B; Hazra T
Management of small cell carcinoma of the lung: therapy, staging, and biochemical markers.
Cancer 1976;38(3):1394-401.
1976: Baylin S B; Gann D S; Hsu S H
Clonal origin of inherited medullary thyroid carcinoma and pheochromocytoma.
Science (New York, N.Y.) 1976;193(4250):321-3.
1975: Baylin S B; Abeloff M D; Wieman K C; Tomford J W; Ettinger D S
Elevated histaminase (diamine oxidase) activity in small-cell carcinoma of the lung.
The New England journal of medicine 1975;293(25):1286-90.
1975: Beaven M A; Marshall J R; Baylin S B; Sjoerdsma A
Changes in plasma histaminase activity during normal early human pregnancy and pregnancy disorders.
American journal of obstetrics and gynecology 1975;123(6):605-9.
1975: Baylin S B; Margolis S
Purification of histaminase (diamine oxidase) from human pregnancy plasma by affinity chromatography.
Biochimica et biophysica acta 1975;397(2):294-306.
1975: Baylin S; Horakova Z; Beaven M A
Increase in food consumption and growth after treatment with aminoguanidine.
Experientia 1975;31(5):562-4.
1974: Baylin S B
Medullary carcinoma of the thyroid gland: use of biochemical parameters in detection and surgical management of the tumor.
The Surgical clinics of North America 1974;54(2):309-23.
1973: Knights E B; Baylin S B; Foster G V
Control of polypeptide hormones by enzymatic degradation.
Lancet 1973;2(7831):719-23.
1973: Baylin S B; Beaven M A; Krauss R M; Keiser H R
Response of plasma histaminase activity to small doses of heparin in normal subjects and patients with hyperlipoproteinemia.
The Journal of clinical investigation 1973;52(8):1985-93.
1972: Baylin S B; Beaven M A; Buja L M; Keiser H R
Histaminase activity: a biochemical marker for medullary carcinoma of the thyroid.
The American journal of medicine 1972;53(6):723-33.
1972: Baylin S B; Beaven M A; Keiser H R; Tashjian A H; Melvin K E
Serum histaminase and calcitonin levels in medullary carcinoma of the thyroid.
Lancet 1972;1(7748):455-8.
1970: Baylin S B; Beaven M A; Engelman K; Sjoerdsma A
Elevated histaminase activity in medullary carcinoma of the thyroid gland.
The New England journal of medicine 1970;283(23):1239-44.

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