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Xiang-Jin Meng

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Xiang-Jin Meng
Zoonotic and foodborne transmission of hepatitis E virus.
Tanja Opriessnig; Chong Wang; Lei Zhou; Xiang-Jin Meng; Kevin O'Neill; Nathan M Beach; Alessandra M M G de Castro; Priscilla F Gerber; Luis G Gimenéz-Lirola; Patrick G Halbur
A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection.
Yan-Yan Ni; Tanja Opriessnig; Lei Zhou; Dianjun Cao; Patrick G Halbur; Yao-Wei Huang; Xiang-Jin Meng
Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of virus envelope genes from genetically divergent strains.

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All Publications

2013: Xiang-Jin Meng
Zoonotic and foodborne transmission of hepatitis E virus.
Seminars in liver disease 2013;33(1):41-9.
2013: Tanja Opriessnig; Chong Wang; Lei Zhou; Xiang-Jin Meng; Kevin O'Neill; Nathan M Beach; Alessandra M M G de Castro; Priscilla F Gerber; Luis G Gimenéz-Lirola; Patrick G Halbur
A PCV2 vaccine based on genotype 2b is more effective than a 2a-based vaccine to protect against PCV2b or combined PCV2a/2b viremia in pigs with concurrent PCV2, PRRSV and PPV infection.
Vaccine 2013;31(3):487-94.
2013: Yan-Yan Ni; Tanja Opriessnig; Lei Zhou; Dianjun Cao; Patrick G Halbur; Yao-Wei Huang; Xiang-Jin Meng
Attenuation of porcine reproductive and respiratory syndrome virus by molecular breeding of virus envelope genes from genetically divergent strains.
Journal of virology 2013;87(1):304-13.
2012: Jianzhong Hu; Xiang-Jin Meng; Yanyan Ni; Chenming Zhang
Expression and purification of a chimeric protein consisting of the ectodomains of M and GP5 proteins of porcine reproductive and respiratory syndrome virus (PRRSV).
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;911():43-8.
2012: Lei Zhou; Yan-Yan Ni; Pablo Piñeyro; Brenton J Sanford; Dian-Jun Cao; Caitlin M Cossaboom; Barbara A Dryman; Yao-Wei Huang; Xiang-Jin Meng
DNA shuffling of the GP3 genes of porcine reproductive and respiratory syndrome virus (PRRSV) produces a chimeric virus with an improved cross-neutralizing ability against a heterologous PRRSV strain.
Virology 2012;434(1):96-109.
2012: Caitlin M Cossaboom; Dianjun Cao; Laura Córdoba; Yan-Yan Ni; Xiang-Jin Meng
Complete genome sequence of hepatitis E virus from rabbits in the United States.
Journal of virology 2012;86(23):13124-5.
2012: T E Cecere; N M Beach; Xiang-Jin Meng; Y Y Ni; Kevin D Pelzer; S M Todd; T Leroith
Co-infection of porcine dendritic cells with porcine circovirus type 2a (PCV2a) and genotype II porcine reproductive and respiratory syndrome virus (PRRSV) induces CD4(+)CD25(+)FoxP3(+) T cells in vitro.
Veterinary microbiology 2012;160(1-2):233-9.
2012: Laura Córdoba; Caitlin M Cossaboom; Barbara A Dryman; Alicia R Feagins; Yao-Wei Huang; Tanja Opriessnig; Xiang-Jin Meng
Rescue of a genotype 4 human hepatitis E virus from cloned cDNA and characterization of intergenotypic chimeric viruses in cultured human liver cells and in pigs.
The Journal of general virology 2012;93(Pt 10):2183-94.
2012: Yao-Wei Huang; Barbara A Dryman; Kylie K Harrall; Tanja Opriessnig; Michael Roof; Eric M Vaughn; Xiang-Jin Meng
Serological profile of torque teno sus virus species 1 (TTSuV1) in pigs and antigenic relationships between two TTSuV1 genotypes (1a and 1b), between two species (TTSuV1 and -2), and between porcine and human anelloviruses.
Journal of virology 2012;86(19):10628-39.
2012: Brenton J Sanford; Tanja Opriessnig; Laura Córdoba; Barbara A Dryman; Scott P Kenney; Xiang-Jin Meng
Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs.
Vaccine 2012;30(44):6249-55.
2012: Michelle Hemann; Xiang-Jin Meng; Nathan M Beach; Patrick G Halbur; Hui-Gang Shen; Tanja Opriessnig
Expression of human CD46 has no effect on porcine circovirus type 2 infection and shedding in the experimental pig model.
Veterinary research communications 2012;36(3):187-93.
2012: Caitlin M Cossaboom; Barbara A Dryman; Scott P Kenney; Pablo Piñeyro; Brenton J Sanford; Youchun Wang; Laura Córdoba; Xiang-Jin Meng
Cross-species infection of pigs with a novel rabbit, but not rat, strain of hepatitis E virus isolated in the United States.
The Journal of general virology 2012;93(Pt 8):1687-95.
2012: Tanja Opriessnig; Huigang Shen; Chong Wang; Xiang-Jin Meng; Nathan M Beach; Kay S Faaberg; Phillip C Gauger; Patrick G Halbur
Effect of porcine circovirus type 2a or 2b on infection kinetics and pathogenicity of two genetically divergent strains of porcine reproductive and respiratory syndrome virus in the conventional pig model.
Veterinary microbiology 2012;158(1-2):69-81.
2012: Avanti Sinha; Chong Wang; Huigang Shen; Nathan M Beach; Patrick G Halbur; Michelle Hemann; Carmen Ledesma; Kathy Lin; Xiang-Jin Meng; Tanja Opriessnig
ORF1 but not ORF2 dependent differences are important for in vitro replication of PCV2 in porcine alveolar macrophages singularly or coinfected with PRRSV.
Veterinary microbiology 2012;158(1-2):95-103.
2012: M Hemann; Xiang-Jin Meng; N M Beach; Patrick G Halbur; Tanja Opriessnig
Vaccination with inactivated or live-attenuated chimeric PCV1-2 results in decreased viremia in challenge-exposed pigs and may reduce transmission of PCV2.
Veterinary microbiology 2012;158(1-2):180-6.
2012: Chao-Ting Xiao; Luis Giménez-Lirola; Patrick G Halbur; Yao-Wei Huang; Xiang-Jin Meng; Tanja Opriessnig
The prevalence of Torque teno sus virus (TTSuV) is common and increases with the age of growing pigs in the United States.
Journal of virological methods 2012;183(1):40-4.
2012: Yao-Wei Huang; Barbara A Dryman; Andreas Gallei; Kylie K Harrall; Tanja Opriessnig; Abby R Patterson; Michael B Roof; Eric M Vaughn; Xiang-Jin Meng
Rescue of a porcine anellovirus (torque teno sus virus 2) from cloned genomic DNA in pigs.
Journal of virology 2012;86(11):6042-54.
2012: Scott P Kenney; Tanya LeRoith; F William Pierson; R S Pudupakam; Yao-Wei Huang; Xiang-Jin Meng
The PSAP motif within the ORF3 protein of an avian strain of the hepatitis E virus is not critical for viral infectivity in vivo but plays a role in virus release.
Journal of virology 2012;86(10):5637-46.
2012: Yogesh A Karpe; Xiang-Jin Meng
Hepatitis E virus replication requires an active ubiquitin-proteasome system.
Journal of virology 2012;86(10):5948-52.
2012: Jianzhong Hu; Xiang-Jin Meng; Yanyan Ni; Barbara A Dryman; Chenming Zhang
Immunogenicity study of plant-made oral subunit vaccine against porcine reproductive and respiratory syndrome virus (PRRSV).
Vaccine 2012;30(12):2068-74.
2012: Xiang-Jin Meng
Spread like a wildfire--the omnipresence of porcine circovirus type 2 (PCV2) and its ever-expanding association with diseases in pigs.
Virus research 2012;164(1-2):1-3.
2012: Nathan M Beach; Xiang-Jin Meng
Efficacy and future prospects of commercially available and experimental vaccines against porcine circovirus type 2 (PCV2).
Virus research 2012;164(1-2):33-42.
2011: Caitlin M Cossaboom; Barbara A Dryman; Laura Córdoba; Xiang-Jin Meng
Hepatitis E virus in rabbits, Virginia, USA.
Emerging infectious diseases 2011;17(11):2047-9.
2011: K C O'Neill; H G Shen; N M Beach; Patrick G Halbur; M Hemann; K Lin; Xiang-Jin Meng; Tanja Opriessnig
Studies on porcine circovirus type 2 vaccination of 5-day-old piglets.
Clinical and vaccine immunology : CVI 2011;18(11):1865-71.
2011: Nathan M Beach; Laura Córdoba; Scott P Kenney; Xiang-Jin Meng
Productive infection of human hepatocellular carcinoma cells by porcine circovirus type 1.
Vaccine 2011;29(43):7303-6.
2011: R S Pudupakam; F William Pierson; Laura Córdoba; Barbara A Dryman; Yao-Wei Huang; Scott P Kenney; Tanya Leroith; Xiang-Jin Meng
Mutational analysis of the hypervariable region of hepatitis e virus reveals its involvement in the efficiency of viral RNA replication.
Journal of virology 2011;85(19):10031-40.
2011: Xiang-Jin Meng
From barnyard to food table: the omnipresence of hepatitis E virus and risk for zoonotic infection and food safety.
Virus research 2011;161(1):23-30.
2011: A Sinha; S Schalk; H G Shen; N M Beach; Patrick G Halbur; Y W Huang; Xiang-Jin Meng; Tanja Opriessnig
Porcine reproductive and respiratory syndrome virus (PRRSV) influences infection dynamics of porcine circovirus type 2 (PCV2) subtypes PCV2a and PCV2b by prolonging PCV2 viremia and shedding.
Veterinary microbiology 2011;152(3-4):235-46.
2011: Yan-Yan Ni; Tanja Opriessnig; Dianjun Cao; Yao-Wei Huang; Xiang-Jin Meng
Establishment of a DNA-launched infectious clone for a highly pneumovirulent strain of type 2 porcine reproductive and respiratory syndrome virus: identification and in vitro and in vivo characterization of a large spontaneous deletion in the nsp2 region.
Virus research 2011;160(1-2):264-73.
2011: H Zhang; J R Prickett; S Schalk; A R Feagins; Patrick G Halbur; Xiang-Jin Meng; U Mohn; M Motz; Tanja Opriessnig
Differences in capabilities of different enzyme immunoassays to detect anti-hepatitis E virus immunoglobulin G in pigs infected experimentally with hepatitis E virus genotype 3 or 4 and in pigs with unknown exposure.
Journal of virological methods 2011;175(2):156-62.
2011: Tanja Opriessnig; S Ramamoorthy; Michael Roof; S M Layton; D M Madson; Xiang-Jin Meng; Patrick G Halbur
Experimental reproduction of porcine circovirus type 2 (PCV2)-associated enteritis in pigs infected with PCV2 alone or concurrently with Lawsonia intracellularis or Salmonella typhimurium.
Journal of comparative pathology 2011;145(2-3):261-70.
2011: Tanja Opriessnig; S Schalk; H G Shen; E L Zanella; R B Baker; N M Beach; Susan L Brockmeier; D M Madson; Xiang-Jin Meng; Patrick G Halbur
Porcine circovirus type 2 (PCV2) vaccination is effective in reducing disease and PCV2 shedding in semen of boars concurrently infected with PCV2 and Mycoplasma hyopneumoniae.
Theriogenology 2011;76(2):351-60.
2011: Tanja Opriessnig; Deendayal Patel; David A Stein; Rong Wang; Patrick G Halbur; Xiang-Jin Meng; Yanjin Zhang
Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer.
Antiviral research 2011;91(1):36-42.
2011: Brenton J Sanford; Barbara A Dryman; Yao-Wei Huang; Alicia R Feagins; Tanya Leroith; Xiang-Jin Meng
Prior infection of pigs with a genotype 3 swine hepatitis E virus (HEV) protects against subsequent challenges with homologous and heterologous genotypes 3 and 4 human HEV.
Virus research 2011;159(1):17-22.
2011: Laura Córdoba; Yao-Wei Huang; Tanja Opriessnig; Kylie K Harral; Nathan M Beach; Carla V Finkielstein; Suzanne U Emerson; Xiang-Jin Meng
Three amino acid mutations (F51L, T59A, and S390L) in the capsid protein of the hepatitis E virus collectively contribute to virus attenuation.
Journal of virology 2011;85(11):5338-49.
2011: Y W Huang; K K Harrall; B A Dryman; N M Beach; S P Kenney; Tanja Opriessnig; E M Vaughn; M B Roof; Xiang-Jin Meng
Expression of the putative ORF1 capsid protein of Torque teno sus virus 2 (TTSuV2) and development of Western blot and ELISA serodiagnostic assays: correlation between TTSuV2 viral load and IgG antibody level in pigs.
Virus research 2011;158(1-2):79-88.
2011: Nathan M Beach; Sara M Smith; Sheela Ramamoorthy; Xiang-Jin Meng
Chimeric porcine circoviruses (PCV) containing amino acid epitope tags in the C terminus of the capsid gene are infectious and elicit both anti-epitope tag antibodies and anti-PCV type 2 neutralizing antibodies in pigs.
Journal of virology 2011;85(9):4591-5.
2011: A R Patterson; S Ramamoorthy; D M Madson; Xiang-Jin Meng; Patrick G Halbur; Tanja Opriessnig
Shedding and infection dynamics of porcine circovirus type 2 (PCV2) after experimental infection.
Veterinary microbiology 2011;149(1-2):91-8.
2011: Abby R Patterson; John K Johnson; Sheela Ramamoorthy; Richard A Hesse; Michael P Murtaugh; Sumathy Puvanendiran; Roman M Pogranichniy; Gene A Erickson; Susy Carman; Ben Hause; Xiang-Jin Meng; Tanja Opriessnig
Interlaboratory comparison of Porcine circovirus-2 indirect immunofluorescent antibody test and enzyme-linked immunosorbent assay results on experimentally infected pigs.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2011;23(2):206-12.
2011: Alicia R Feagins; Laura Córdoba; Brent J Sanford; Barbara A Dryman; Yao-Wei Huang; Tanya LeRoith; Suzanne U Emerson; Xiang-Jin Meng
Intergenotypic chimeric hepatitis E viruses (HEVs) with the genotype 4 human HEV capsid gene in the backbone of genotype 3 swine HEV are infectious in pigs.
Virus research 2011;156(1-2):141-6.
2011: Hyuk Moo Kwon; Tanya LeRoith; R S Pudupakam; F William Pierson; Yao-Wei Huang; Barbara A Dryman; Xiang-Jin Meng
Construction of an infectious cDNA clone of avian hepatitis E virus (avian HEV) recovered from a clinically healthy chicken in the United States and characterization of its pathogenicity in specific-pathogen-free chickens.
Veterinary microbiology 2011;147(3-4):310-9.
2011: Sheela Ramamoorthy; Tanja Opriessnig; Narinder Pal; FF Huang; Xiang-Jin Meng
Effect of an interferon-stimulated response element (ISRE) mutant of porcine circovirus type 2 (PCV2) on PCV2-induced pathological lesions in a porcine reproductive and respiratory syndrome virus (PRRSV) co-infection model.
Veterinary microbiology 2011;147(1-2):49-58.
2010: Nathan M Beach; Sheela Ramamoorthy; Tanja Opriessnig; Stephen Q Wu; Xiang-Jin Meng
Novel chimeric porcine circovirus (PCV) with the capsid gene of the emerging PCV2b subtype cloned in the genomic backbone of the non-pathogenic PCV1 is attenuated in vivo and induces protective and cross-protective immunity against PCV2b and PCV2a subtypes in pigs.
Vaccine 2010;29(2):221-32.
2010: Dianjun Cao; Yao-Wei Huang; Xiang-Jin Meng
The nucleotides on the stem-loop RNA structure in the junction region of the hepatitis E virus genome are critical for virus replication.
Journal of virology 2010;84(24):13040-4.
2010: A Sinha; H G Shen; S Schalk; N M Beach; Y W Huang; Patrick G Halbur; Xiang-Jin Meng; Tanja Opriessnig
Porcine reproductive and respiratory syndrome virus infection at the time of porcine circovirus type 2 vaccination has no impact on vaccine efficacy.
Clinical and vaccine immunology : CVI 2010;17(12):1940-5.
2010: Y W Huang; B A Dryman; K K Harrall; E M Vaughn; M B Roof; Xiang-Jin Meng
Development of SYBR green-based real-time PCR and duplex nested PCR assays for quantitation and differential detection of species- or type-specific porcine Torque teno viruses.
Journal of virological methods 2010;170(1-2):140-6.
2010: Y W Huang; Xiang-Jin Meng
Novel strategies and approaches to develop the next generation of vaccines against porcine reproductive and respiratory syndrome virus (PRRSV).
Virus research 2010;154(1-2):141-9.
2010: N M Beach; N M Juhan; L Cordoba; Xiang-Jin Meng
Replacement of the replication factors of porcine circovirus (PCV) type 2 with those of PCV type 1 greatly enhances viral replication in vitro.
Journal of virology 2010;84(17):8986-9.
2010: H G Shen; N M Beach; Y W Huang; Patrick G Halbur; Xiang-Jin Meng; Tanja Opriessnig
Comparison of commercial and experimental porcine circovirus type 2 (PCV2) vaccines using a triple challenge with PCV2, porcine reproductive and respiratory syndrome virus (PRRSV), and porcine parvovirus (PPV).
Vaccine 2010;28(37):5960-6.
2010: Jianzhong Hu; Yanyan Ni; Barbara A Dryman; Xiang-Jin Meng; Chenming Zhang
Purification of porcine reproductive and respiratory syndrome virus from cell culture using ultrafiltration and heparin affinity chromatography.
Journal of chromatography. A 2010;1217(21):3489-93.
2010: Tanja Opriessnig; John R Prickett; Darin M Madson; Hui-Gang Shen; Nicole M Juhan; Roman R Pogranichniy; Xiang-Jin Meng; Patrick G Halbur
Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pathological and clinical effects in growing pigs.
Veterinary research 2010;41(3):31.
2010: Xiang-Jin Meng
Recent advances in Hepatitis E virus.
Journal of viral hepatitis 2010;17(3):153-61.
2010: Xiang-Jin Meng
Hepatitis E virus: animal reservoirs and zoonotic risk.
Veterinary microbiology 2010;140(3-4):256-65.
2010: Y W Huang; Y Y Ni; B A Dryman; Xiang-Jin Meng
Multiple infection of porcine Torque teno virus in a single pig and characterization of the full-length genomic sequences of four U.S. prototype PTTV strains: implication for genotyping of PTTV.
Virology 2010;396(2):289-97.
2010: N M Juhan; T LeRoith; Tanja Opriessnig; Xiang-Jin Meng
The open reading frame 3 (ORF3) of porcine circovirus type 2 (PCV2) is dispensable for virus infection but evidence of reduced pathogenicity is limited in pigs infected by an ORF3-null PCV2 mutant.
Virus research 2010;147(1):60-6.
2009: P Billam; T LeRoith; R S Pudupakam; F William Pierson; Robert B Duncan; Xiang-Jin Meng
Comparative pathogenesis in specific-pathogen-free chickens of two strains of avian hepatitis E virus recovered from a chicken with Hepatitis-Splenomegaly syndrome and from a clinically healthy chicken.
Veterinary microbiology 2009;139(3-4):253-61.
2009: J Gillespie; Tanja Opriessnig; Xiang-Jin Meng; Kevin D Pelzer; Virginia Buechner-Maxwell
Porcine circovirus type 2 and porcine circovirus-associated disease.
Journal of veterinary internal medicine / American College of Veterinary Internal Medicine 2009;23(6):1151-63.
2009: Sheela Ramamoorthy; FF Huang; Y W Huang; Xiang-Jin Meng
Interferon-mediated enhancement of in vitro replication of porcine circovirus type 2 is influenced by an interferon-stimulated response element in the PCV2 genome.
Virus research 2009;145(2):236-43.
2009: D M Madson; A R Patterson; S Ramamoorthy; Narinder Pal; Xiang-Jin Meng; Tanja Opriessnig
Effect of natural or vaccine-induced porcine circovirus type 2 (PCV2) immunity on fetal infection after artificial insemination with PCV2 spiked semen.
Theriogenology 2009;72(6):747-54.
2009: Y W Huang; Y Fang; Xiang-Jin Meng
Identification and characterization of a porcine monocytic cell line supporting porcine reproductive and respiratory syndrome virus (PRRSV) replication and progeny virion production by using an improved DNA-launched PRRSV reverse genetics system.
Virus research 2009;145(1):1-8.
2009: Xiang-Jin Meng; David S Lindsay; Nammalwar Sriranganathan
Wild boars as sources for infectious diseases in livestock and humans.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2009;364(1530):2697-707.
2009: Nathan M Beach; Robert B Duncan; Calvert T Larsen; Xiang-Jin Meng; Nammalwar Sriranganathan; F William Pierson
Persistent infection of turkeys with an avirulent strain of turkey hemorrhagic enteritis virus.
Avian diseases 2009;53(3):370-5.
2009: Nathan M Beach; Robert B Duncan; Calvert T Larsen; Xiang-Jin Meng; Nammalwar Sriranganathan; F William Pierson
Comparison of 12 turkey hemorrhagic enteritis virus isolates allows prediction of genetic factors affecting virulence.
The Journal of general virology 2009;90(Pt 8):1978-85.
2009: D M Madson; A R Patterson; S Ramamoorthy; Narinder Pal; Xiang-Jin Meng; Tanja Opriessnig
Reproductive failure experimentally induced in sows via artificial insemination with semen spiked with porcine circovirus type 2.
Veterinary pathology 2009;46(4):707-16.
2009: D M Madson; A R Patterson; S Ramamoorthy; Narinder Pal; Xiang-Jin Meng; Tanja Opriessnig
Effect of porcine circovirus type 2 (PCV2) vaccination of the dam on PCV2 replication in utero.
Clinical and vaccine immunology : CVI 2009;16(6):830-4.
2009: Y W Huang; Xiang-Jin Meng
Identification of a porcine DC-SIGN-related C-type lectin, porcine CLEC4G (LSECtin), and its order of intron removal during splicing: comparative genomic analyses of the cluster of genes CD23/CLEC4G/DC-SIGN among mammalian species.
Developmental and comparative immunology 2009;33(6):747-60.
2009: Sheela Ramamoorthy; Xiang-Jin Meng
Porcine circoviruses: a minuscule yet mammoth paradox.
Animal health research reviews / Conference of Research Workers in Animal Diseases 2009;10(1):1-20.
2009: Bibiana Peralta; Mar Biarnés; Germán Ordóñez; Ramon Porta; Marga Martín; Enric Mateu; Sonia Pina; Xiang-Jin Meng
Evidence of widespread infection of avian hepatitis E virus (avian HEV) in chickens from Spain.
Veterinary microbiology 2009;137(1-2):31-6.
2009: Tanja Opriessnig; A R Patterson; D M Madson; Narinder Pal; M Rothschild; Daniel Kuhar; Joan K Lunney; N M Juhan; Xiang-Jin Meng; Patrick G Halbur
Difference in severity of porcine circovirus type two-induced pathological lesions between Landrace and Pietrain pigs.
Journal of animal science 2009;87(5):1582-90.
2009: Tanja Opriessnig; Abby R Patterson; Douglas E Jones; Nicole M Juhan; Xiang-Jin Meng; Patrick G Halbur
Limited susceptibility of three different mouse (Mus musculus) lines to Porcine circovirus-2 infection and associated lesions.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2009;73(2):81-6.
2009: Y W Huang; B A Dryman; W Li; Xiang-Jin Meng
Porcine DC-SIGN: molecular cloning, gene structure, tissue distribution and binding characteristics.
Developmental and comparative immunology 2009;33(4):464-80.
2009: R S Pudupakam; Y W Huang; Tanja Opriessnig; Patrick G Halbur; F William Pierson; Xiang-Jin Meng
Deletions of the hypervariable region (HVR) in open reading frame 1 of hepatitis E virus do not abolish virus infectivity: evidence for attenuation of HVR deletion mutants in vivo.
Journal of virology 2009;83(1):384-95.
2009: Tanja Opriessnig; Abby R Patterson; Xiang-Jin Meng; Patrick G Halbur
Porcine circovirus type 2 in muscle and bone marrow is infectious and transmissible to naïve pigs by oral consumption.
Veterinary microbiology 2009;133(1-2):54-64.
2008: Abby R Patterson; John Johnson; Sheela Ramamoorthy; Xiang-Jin Meng; Patrick G Halbur; Tanja Opriessnig
Comparison of three enzyme-linked immunosorbent assays to detect Porcine circovirus-2 (PCV-2)-specific antibodies after vaccination or inoculation of pigs with distinct PCV-1 or PCV-2 isolates.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2008;20(6):744-51.
2008: Darin M Madson; Sheela Ramamoorthy; Chris Kuster; Narinder Pal; Xiang-Jin Meng; Patrick G Halbur; Tanja Opriessnig
Characterization of shedding patterns of Porcine circovirus types 2a and 2b in experimentally inoculated mature boars.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2008;20(6):725-34.
2008: Tanja Opriessnig; S Ramamoorthy; D M Madson; A R Patterson; N Pal; S Carman; Xiang-Jin Meng; Patrick G Halbur
Differences in virulence among porcine circovirus type 2 isolates are unrelated to cluster type 2a or 2b and prior infection provides heterologous protection.
The Journal of general virology 2008;89(Pt 10):2482-91.
2008: J Gillespie; N M Juhan; Jennifer A Dicristina; KF Key; S Ramamoorthy; Xiang-Jin Meng
A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) is genetically stable in vitro and in vivo.
Vaccine 2008;26(33):4231-6.
2008: P Billam; F William Pierson; W Li; T LeRoith; Robert B Duncan; Xiang-Jin Meng
Development and validation of a negative-strand-specific reverse transcription-PCR assay for detection of a chicken strain of hepatitis E virus: identification of nonliver replication sites.
Journal of clinical microbiology 2008;46(8):2630-4.
2008: A R Feagins; Tanja Opriessnig; Y W Huang; Patrick G Halbur; Xiang-Jin Meng
Cross-species infection of specific-pathogen-free pigs by a genotype 4 strain of human hepatitis E virus.
Journal of medical virology 2008;80(8):1379-86.
2008: N Pal; Y W Huang; D M Madson; C Kuster; Xiang-Jin Meng; Patrick G Halbur; Tanja Opriessnig
Development and validation of a duplex real-time PCR assay for the simultaneous detection and quantification of porcine circovirus type 2 and an internal control on porcine semen samples.
Journal of virological methods 2008;149(2):217-25.
2008: A R Feagins; Tanja Opriessnig; Denis K Guenette; Patrick G Halbur; Xiang-Jin Meng
Inactivation of infectious hepatitis E virus present in commercial pig livers sold in local grocery stores in the United States.
International journal of food microbiology 2008;123(1-2):32-7.
2008: H Guo; En-Min Zhou; ZF Sun; Xiang-Jin Meng
Immunodominant epitopes mapped by synthetic peptides on the capsid protein of avian hepatitis E virus are non-protective.
Viral immunology 2008;21(1):61-7.
2008: Tanja Opriessnig; A R Patterson; J Elsener; Xiang-Jin Meng; Patrick G Halbur
Influence of maternal antibodies on efficacy of porcine circovirus type 2 (PCV2) vaccination to protect pigs from experimental infection with PCV2.
Clinical and vaccine immunology : CVI 2008;15(3):397-401.
2008: En-Min Zhou; H Guo; FF Huang; ZF Sun; Xiang-Jin Meng
Identification of two neutralization epitopes on the capsid protein of avian hepatitis E virus.
The Journal of general virology 2008;89(Pt 2):500-8.
2008: Brad M Matanin; Yaowei Huang; Xiang-Jin Meng; Chenming Zhang
Purification of the major envelop protein GP5 of porcine reproductive and respiratory syndrome virus (PRRSV) from native virions.
Journal of virological methods 2008;147(1):127-35.
2007: Tanja Opriessnig; Xiang-Jin Meng; Patrick G Halbur
Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 2007;19(6):591-615.
2007: Marga Martín; Segales Joaquim; FF Huang; Denis K Guenette; Enric Mateu; N de Deus; Xiang-Jin Meng
Association of hepatitis E virus (HEV) and postweaning multisystemic wasting syndrome (PMWS) with lesions of hepatitis in pigs.
Veterinary microbiology 2007;122(1-2):16-24.
2007: P Billam; ZF Sun; Xiang-Jin Meng
Analysis of the complete genomic sequence of an apparently avirulent strain of avian hepatitis E virus (avian HEV) identified major genetic differences compared with the prototype pathogenic strain of avian HEV.
The Journal of general virology 2007;88(Pt 5):1538-44.
2007: H Guo; En-Min Zhou; ZF Sun; Xiang-Jin Meng
Egg whites from eggs of chickens infected experimentally with avian hepatitis E virus contain infectious virus, but evidence of complete vertical transmission is lacking.
The Journal of general virology 2007;88(Pt 5):1532-7.
2007: H Guo; En-Min Zhou; ZF Sun; Xiang-Jin Meng
Protection of chickens against avian hepatitis E virus (avian HEV) infection by immunization with recombinant avian HEV capsid protein.
Vaccine 2007;25(15):2892-9.
2007: A R Feagins; Tanja Opriessnig; Denis K Guenette; Patrick G Halbur; Xiang-Jin Meng
Detection and characterization of infectious Hepatitis E virus from commercial pig livers sold in local grocery stores in the USA.
The Journal of general virology 2007;88(Pt 3):912-7.
2007: Y W Huang; Tanja Opriessnig; Patrick G Halbur; Xiang-Jin Meng
Initiation at the third in-frame AUG codon of open reading frame 3 of the hepatitis E virus is essential for viral infectivity in vivo.
Journal of virology 2007;81(6):3018-26.
2007: KF Key; Jennifer A Dicristina; J Gillespie; Denis K Guenette; Xiang-Jin Meng
Direct inoculation of RNA transcripts from an infectious cDNA clone of porcine reproductive and respiratory syndrome virus (PRRSV) into the lymph nodes and tonsils of pigs initiates PRRSV infection in vivo.
Archives of virology 2007;152(7):1383-7.
2006: Tanja Opriessnig; NE McKeown; En-Min Zhou; Xiang-Jin Meng; Patrick G Halbur
Genetic and experimental comparison of porcine circovirus type 2 (PCV2) isolates from cases with and without PCV2-associated lesions provides evidence for differences in virulence.
The Journal of general virology 2006;87(Pt 10):2923-32.
2006: Tanja Opriessnig; NE McKeown; K L Harmon; Xiang-Jin Meng; Patrick G Halbur
Porcine circovirus type 2 infection decreases the efficacy of a modified live porcine reproductive and respiratory syndrome virus vaccine.
Clinical and vaccine immunology : CVI 2006;13(8):923-9.
2006: Tanja Opriessnig; M Fenaux; P Thomas; M J Hoogland; M F Rothschild; Xiang-Jin Meng; Patrick G Halbur
Evidence of breed-dependent differences in susceptibility to porcine circovirus type-2-associated disease and lesions.
Veterinary pathology 2006;43(3):281-93.
2006: Tanja Opriessnig; Patrick G Halbur; Shan Yu; Eileen L Thacker; M Fenaux; Xiang-Jin Meng
Effects of the timing of the administration of Mycoplasma hyopneumoniae bacterin on the development of lesions associated with porcine circovirus type 2.
The Veterinary record 2006;158(5):149-54.
2006: H Guo; En-Min Zhou; ZF Sun; Xiang-Jin Meng; Patrick G Halbur
Identification of B-cell epitopes in the capsid protein of avian hepatitis E virus (avian HEV) that are common to human and swine HEVs or unique to avian HEV.
The Journal of general virology 2006;87(Pt 1):217-23.
2005: Chaiyan Kasorndorkbua; Tanja Opriessnig; FF Huang; Denis K Guenette; PJ Thomas; Xiang-Jin Meng; Patrick G Halbur
Infectious swine hepatitis E virus is present in pig manure storage facilities on United States farms, but evidence of water contamination is lacking.
Applied and environmental microbiology 2005;71(12):7831-7.
2005: NE McKeown; Tanja Opriessnig; P Thomas; Denis K Guenette; François Elvinger; M Fenaux; Patrick G Halbur; Xiang-Jin Meng
Effects of porcine circovirus type 2 (PCV2) maternal antibodies on experimental infection of piglets with PCV2.
Clinical and diagnostic laboratory immunology 2005;12(11):1347-51.
2005: FF Huang; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Construction and characterization of infectious cDNA clones of a chicken strain of hepatitis E virus (HEV), avian HEV.
The Journal of general virology 2005;86(Pt 9):2585-93.
2005: K Cooper; FF Huang; L Batista; C D Rayo; J C Bezanilla; Thomas E Toth; Xiang-Jin Meng
Identification of genotype 3 hepatitis E virus (HEV) in serum and fecal samples from pigs in Thailand and Mexico, where genotype 1 and 2 HEV strains are prevalent in the respective human populations.
Journal of clinical microbiology 2005;43(4):1684-8.
2005: P Billam; FF Huang; ZF Sun; F William Pierson; Robert B Duncan; François Elvinger; Denis K Guenette; Thomas E Toth; Xiang-Jin Meng
Systematic pathogenesis and replication of avian hepatitis E virus in specific-pathogen-free adult chickens.
Journal of virology 2005;79(6):3429-37.
2005: Y W Huang; G Haqshenas; Chaiyan Kasorndorkbua; Patrick G Halbur; Suzanne U Emerson; Xiang-Jin Meng
Capped RNA transcripts of full-length cDNA clones of swine hepatitis E virus are replication competent when transfected into Huh7 cells and infectious when intrahepatically inoculated into pigs.
Journal of virology 2005;79(3):1552-8.
2004: M Fenaux; Tanja Opriessnig; Patrick G Halbur; François Elvinger; Xiang-Jin Meng
Two amino acid mutations in the capsid protein of type 2 porcine circovirus (PCV2) enhanced PCV2 replication in vitro and attenuated the virus in vivo.
Journal of virology 2004;78(24):13440-6.
2004: NE McKeown; M Fenaux; Patrick G Halbur; Xiang-Jin Meng
Molecular characterization of porcine TT virus, an orphan virus, in pigs from six different countries.
Veterinary microbiology 2004;104(1-2):113-7.
2004: Tanja Opriessnig; Eileen L Thacker; Shan Yu; M Fenaux; Xiang-Jin Meng; Patrick G Halbur
Experimental reproduction of postweaning multisystemic wasting syndrome in pigs by dual infection with Mycoplasma hyopneumoniae and porcine circovirus type 2.
Veterinary pathology 2004;41(6):624-40.
2004: Chaiyan Kasorndorkbua; Denis K Guenette; FF Huang; PJ Thomas; Xiang-Jin Meng; Patrick G Halbur
Routes of transmission of swine hepatitis E virus in pigs.
Journal of clinical microbiology 2004;42(11):5047-52.
2004: M Fenaux; Tanja Opriessnig; Patrick G Halbur; Y Xu; B Potts; Xiang-Jin Meng
Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product.
The Journal of general virology 2004;85(Pt 11):3377-82.
2004: Porntippa Lekcharoensuk; Igor Morozov; Prem Paul; Nattarat Thangthumniyom; Worawidh Wajjawalku; Xiang-Jin Meng
Epitope mapping of the major capsid protein of type 2 porcine circovirus (PCV2) by using chimeric PCV1 and PCV2.
Journal of virology 2004;78(15):8135-45.
2004: ZF Sun; Calvert T Larsen; FF Huang; P Billam; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Generation and infectivity titration of an infectious stock of avian hepatitis E virus (HEV) in chickens and cross-species infection of turkeys with avian HEV.
Journal of clinical microbiology 2004;42(6):2658-62.
2004: FF Huang; ZF Sun; Suzanne U Emerson; Robert Purcell; HL Shivaprasad; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Determination and analysis of the complete genomic sequence of avian hepatitis E virus (avian HEV) and attempts to infect rhesus monkeys with avian HEV.
The Journal of general virology 2004;85(Pt 6):1609-18.
2004: M Fenaux; Tanja Opriessnig; Patrick G Halbur; François Elvinger; Xiang-Jin Meng
A chimeric porcine circovirus (PCV) with the immunogenic capsid gene of the pathogenic PCV type 2 (PCV2) cloned into the genomic backbone of the nonpathogenic PCV1 induces protective immunity against PCV2 infection in pigs.
Journal of virology 2004;78(12):6297-303.
2004: ZF Sun; Xiang-Jin Meng
Antigenic cross-reactivity between the nucleocapsid protein of severe acute respiratory syndrome (SARS) coronavirus and polyclonal antisera of antigenic group I animal coronaviruses: implication for SARS diagnosis.
Journal of clinical microbiology 2004;42(5):2351-2.
2004: Tanja Opriessnig; M Fenaux; Shan Yu; Richard B Evans; D Cavanaugh; Jack M Gallup; FJ Pallares; Eileen L Thacker; Kelly M Lager; Xiang-Jin Meng; Patrick G Halbur
Effect of porcine parvovirus vaccination on the development of PMWS in segregated early weaned pigs coinfected with type 2 porcine circovirus and porcine parvovirus.
Veterinary microbiology 2004;98(3-4):209-20.
2004: ZF Sun; Calvert T Larsen; A Dunlop; FF Huang; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Genetic identification of avian hepatitis E virus (HEV) from healthy chicken flocks and characterization of the capsid gene of 14 avian HEV isolates from chickens with hepatitis-splenomegaly syndrome in different geographical regions of the United States.
The Journal of general virology 2004;85(Pt 3):693-700.
2003: ZF Sun; FF Huang; Patrick G Halbur; S K Schommer; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Use of heteroduplex mobility assays (HMA) for pre-sequencing screening and identification of variant strains of swine and avian hepatitis E viruses.
Veterinary microbiology 2003;96(2):165-76.
2003: Chaiyan Kasorndorkbua; Brad J Thacker; Patrick G Halbur; Denis K Guenette; Ryan M Buitenwerf; Ryan L Royer; Xiang-Jin Meng
Experimental infection of pregnant gilts with swine hepatitis E virus.
Canadian journal of veterinary research = Revue canadienne de recherche vétérinaire 2003;67(4):303-6.
2003: M Fenaux; Tanja Opriessnig; Patrick G Halbur; Xiang-Jin Meng
Immunogenicity and pathogenicity of chimeric infectious DNA clones of pathogenic porcine circovirus type 2 (PCV2) and nonpathogenic PCV1 in weanling pigs.
Journal of virology 2003;77(20):11232-43.
2003: Tanja Opriessnig; Shan Yu; Jack M Gallup; Richard B Evans; M Fenaux; FJ Pallares; Eileen L Thacker; Charles W Brockus; Mark R Ackermann; P Thomas; Xiang-Jin Meng; Patrick G Halbur
Effect of vaccination with selective bacterins on conventional pigs infected with type 2 porcine circovirus.
Veterinary pathology 2003;40(5):521-9.
2003: KF Key; Denis K Guenette; Kyoung-Jin Yoon; Patrick G Halbur; Thomas E Toth; Xiang-Jin Meng
Development of a heteroduplex mobility assay to identify field isolates of porcine reproductive and respiratory syndrome virus with nucleotide sequences closely related to those of modified live-attenuated vaccines.
Journal of clinical microbiology 2003;41(6):2433-9.
2003: Xiang-Jin Meng
Swine hepatitis E virus: cross-species infection and risk in xenotransplantation.
Current topics in microbiology and immunology 2003;278():185-216.
2002: ronald engle; C Yu; Suzanne U Emerson; Xiang-Jin Meng; Robert Purcell
Hepatitis E virus (HEV) capsid antigens derived from viruses of human and swine origin are equally efficient for detecting anti-HEV by enzyme immunoassay.
Journal of clinical microbiology 2002;40(12):4576-80.
2002: Tanja Opriessnig; Patrick G Halbur; Kyoung-Jin Yoon; Roman M Pogranichniy; KM Harmon; R Evans; KF Key; FJ Pallares; P Thomas; Xiang-Jin Meng
Comparison of molecular and biological characteristics of a modified live porcine reproductive and respiratory syndrome virus (PRRSV) vaccine (ingelvac PRRS MLV), the parent strain of the vaccine (ATCC VR2332), ATCC VR2385, and two recent field isolates of PRRSV.
Journal of virology 2002;76(23):11837-44.
2002: FF Huang; G Haqshenas; HL Shivaprasad; Denis K Guenette; Peter R Woolcock; Calvert T Larsen; F William Pierson; François Elvinger; Thomas E Toth; Xiang-Jin Meng
Heterogeneity and seroprevalence of a newly identified avian hepatitis e virus from chickens in the United States.
Journal of clinical microbiology 2002;40(11):4197-202.
2002: R G Halbur; Francisco J Pallarés; J A Rathje; R Evans; WA Hagemoser; Prem Paul; Xiang-Jin Meng
Effects of different us isolates of porcine reproductive and respiratory syndrome virus (PRRSV) on blood and bone marrow parameters of experimentally infected pigs.
The Veterinary record 2002;151(12):344-8.
2002: G Haqshenas; FF Huang; M Fenaux; Denis K Guenette; F William Pierson; Calvert T Larsen; HL Shivaprasad; Thomas E Toth; Xiang-Jin Meng
The putative capsid protein of the newly identified avian hepatitis E virus shares antigenic epitopes with that of swine and human hepatitis E viruses and chicken big liver and spleen disease virus.
The Journal of general virology 2002;83(Pt 9):2201-9.
2002: FF Huang; G Haqshenas; Denis K Guenette; Patrick G Halbur; S K Schommer; F William Pierson; Thomas E Toth; Xiang-Jin Meng
Detection by reverse transcription-PCR and genetic characterization of field isolates of swine hepatitis E virus from pigs in different geographic regions of the United States.
Journal of clinical microbiology 2002;40(4):1326-32.
2002: Chaiyan Kasorndorkbua; Patrick G Halbur; PJ Thomas; Denis K Guenette; Thomas E Toth; Xiang-Jin Meng
Use of a swine bioassay and a RT-PCR assay to assess the risk of transmission of swine hepatitis E virus in pigs.
Journal of virological methods 2002;101(1-2):71-8.
2002: Xiang-Jin Meng; B Wiseman; François Elvinger; Denis K Guenette; Thomas E Toth; ronald engle; Suzanne U Emerson; Robert Purcell
Prevalence of antibodies to hepatitis E virus in veterinarians working with swine and in normal blood donors in the United States and other countries.
Journal of clinical microbiology 2002;40(1):117-22.
2002: M Fenaux; Patrick G Halbur; G Haqshenas; Ryan L Royer; P Thomas; P Nawagitgul; M Gill; Thomas E Toth; Xiang-Jin Meng
Cloned genomic DNA of type 2 porcine circovirus is infectious when injected directly into the liver and lymph nodes of pigs: characterization of clinical disease, virus distribution, and pathologic lesions.
Journal of virology 2002;76(2):541-51.
2001: G Haqshenas; Xiang-Jin Meng
Determination of the nucleotide sequences at the extreme 5' and 3' ends of swine hepatitis E virus genome.
Archives of virology 2001;146(12):2461-7.
2001: KF Key; G Haqshenas; Denis K Guenette; S L Swenson; Thomas E Toth; Xiang-Jin Meng
Genetic variation and phylogenetic analyses of the ORF5 gene of acute porcine reproductive and respiratory syndrome virus isolates.
Veterinary microbiology 2001;83(3):249-63.
2001: G Haqshenas; HL Shivaprasad; Peter R Woolcock; D H Read; Xiang-Jin Meng
Genetic identification and characterization of a novel virus related to human hepatitis E virus from chickens with hepatitis-splenomegaly syndrome in the United States.
The Journal of general virology 2001;82(Pt 10):2449-62.
2001: T P Williams; Chaiyan Kasorndorkbua; Patrick G Halbur; G Haqshenas; Denis K Guenette; Thomas E Toth; Xiang-Jin Meng
Evidence of extrahepatic sites of replication of the hepatitis E virus in a swine model.
Journal of clinical microbiology 2001;39(9):3040-6.
2001: Patrick G Halbur; Chaiyan Kasorndorkbua; C Gilbert; Denis K Guenette; M B Potters; Robert Purcell; Suzanne U Emerson; Thomas E Toth; Xiang-Jin Meng
Comparative pathogenesis of infection of pigs with hepatitis E viruses recovered from a pig and a human.
Journal of clinical microbiology 2001;39(3):918-23.
2000: M Fenaux; Patrick G Halbur; M Gill; Thomas E Toth; Xiang-Jin Meng
Genetic characterization of type 2 porcine circovirus (PCV-2) from pigs with postweaning multisystemic wasting syndrome in different geographic regions of North America and development of a differential PCR-restriction fragment length polymorphism assay to detect and differentiate between infections with PCV-1 and PCV-2.
Journal of clinical microbiology 2000;38(7):2494-503.
2000: Xiang-Jin Meng
Heterogeneity of porcine reproductive and respiratory syndrome virus: implications for current vaccine efficacy and future vaccine development.
Veterinary microbiology 2000;74(4):309-29.
1999: Xiang-Jin Meng; S Dea; ronald engle; Robert Friendship; Y S Lyoo; T Sirinarumitr; K Urairong; D Wang; D Wong; D Yoo; Yanjin Zhang; Robert Purcell; Suzanne U Emerson
Prevalence of antibodies to the hepatitis E virus in pigs from countries where hepatitis E is common or is rare in the human population.
Journal of medical virology 1999;59(3):297-302.
1999: Y Kabrane-Lazizi; Xiang-Jin Meng; Robert Purcell; Suzanne U Emerson
Evidence that the genomic RNA of hepatitis E virus is capped.
Journal of virology 1999;73(10):8848-50.
1999: Y Kabrane-Lazizi; Joshua B Fine; J Elm; Gregory E Glass; H Higa; A Diwan; C J Gibbs; Xiang-Jin Meng; Suzanne U Emerson; Robert Purcell
Evidence for widespread infection of wild rats with hepatitis E virus in the United States.
The American journal of tropical medicine and hygiene 1999;61(2):331-5.
1998: Xiang-Jin Meng; Patrick G Halbur; M S Shapiro; S Govindarajan; JD Bruna; I K Mushahwar; Robert Purcell; Suzanne U Emerson
Genetic and experimental evidence for cross-species infection by swine hepatitis E virus.
Journal of virology 1998;72(12):9714-21.
1998: Xiang-Jin Meng; Patrick G Halbur; Joseph S Haynes; TS Tsareva; JD Bruna; Ryan L Royer; Robert Purcell; Suzanne U Emerson
Experimental infection of pigs with the newly identified swine hepatitis E virus (swine HEV), but not with human strains of HEV.
Archives of virology 1998;143(7):1405-15.
1997: Xiang-Jin Meng; Robert Purcell; Patrick G Halbur; J R Lehman; D M Webb; TS Tsareva; Joseph S Haynes; Brad J Thacker; Suzanne U Emerson
A novel virus in swine is closely related to the human hepatitis E virus.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(18):9860-5.
1997: Joseph S Haynes; Patrick G Halbur; T Sirinarumitr; Prem Paul; Xiang-Jin Meng; EL Huffman
Temporal and morphologic characterization of the distribution of porcine reproductive and respiratory syndrome virus (PRRSV) by in situ hybridization in pigs infected with isolates of PRRSV that differ in virulence.
Veterinary pathology 1997;34(1):39-43.
1996: Xiang-Jin Meng; Prem Paul; Patrick G Halbur; M A Lum
Characterization of a high-virulence US isolate of porcine reproductive and respiratory syndrome virus in a continuous cell line, ATCC CRL11171.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1996;8(3):374-81.
1996: Xiang-Jin Meng; Prem Paul; I Morozov; Patrick G Halbur
A nested set of six or seven subgenomic mRNAs is formed in cells infected with different isolates of porcine reproductive and respiratory syndrome virus.
The Journal of general virology 1996;77 ( Pt 6)():1265-70.
1996: Patrick G Halbur; Prem Paul; M L Frey; J Landgraf; K Eernisse; Xiang-Jin Meng; JJ Andrews; M A Lum; J A Rathje
Comparison of the antigen distribution of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus.
Veterinary pathology 1996;33(2):159-70.
1996: Patrick G Halbur; Prem Paul; Xiang-Jin Meng; M A Lum; JJ Andrews; J A Rathje
Comparative pathogenicity of nine US porcine reproductive and respiratory syndrome virus (PRRSV) isolates in a five-week-old cesarean-derived, colostrum-deprived pig model.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1996;8(1):11-20.
1995: Xiang-Jin Meng; Prem Paul; Patrick G Halbur; I Morozov
Sequence comparison of open reading frames 2 to 5 of low and high virulence United States isolates of porcine reproductive and respiratory syndrome virus.
The Journal of general virology 1995;76 ( Pt 12)():3181-8.
1995: Patrick G Halbur; Prem Paul; M L Frey; J Landgraf; K Eernisse; Xiang-Jin Meng; M A Lum; JJ Andrews; J A Rathje
Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus.
Veterinary pathology 1995;32(6):648-60.
1995: Patrick G Halbur; L D Miller; Prem Paul; Xiang-Jin Meng; E L Huffman; JJ Andrews
Immunohistochemical identification of porcine reproductive and respiratory syndrome virus (PRRSV) antigen in the heart and lymphoid system of three-week-old colostrum-deprived pigs.
Veterinary pathology 1995;32(2):200-4.
1995: Xiang-Jin Meng; Prem Paul; Patrick G Halbur; M A Lum
Phylogenetic analyses of the putative M (ORF 6) and N (ORF 7) genes of porcine reproductive and respiratory syndrome virus (PRRSV): implication for the existence of two genotypes of PRRSV in the U.S.A. and Europe.
Archives of virology 1995;140(4):745-55.
1995: I Morozov; Xiang-Jin Meng; Prem Paul
Sequence analysis of open reading frames (ORFs) 2 to 4 of a U.S. isolate of porcine reproductive and respiratory syndrome virus.
Archives of virology 1995;140(7):1313-9.
1994: Xiang-Jin Meng; Prem Paul; Patrick G Halbur
Molecular cloning and nucleotide sequencing of the 3'-terminal genomic RNA of the porcine reproductive and respiratory syndrome virus.
The Journal of general virology 1994;75 ( Pt 7)():1795-801.
1994: Patrick G Halbur; JJ Andrews; E L Huffman; Prem Paul; Xiang-Jin Meng; Yosiya Niyo
Development of a streptavidin-biotin immunoperoxidase procedure for the detection of porcine reproductive and respiratory syndrome virus antigen in porcine lung.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1994;6(2):254-7.
1993: Xiang-Jin Meng; Prem Paul; Eric Vaughn; Jeffrey J Zimmerman
Development of a radiolabeled nucleic acid probe for the detection of encephalomyocarditis virus of swine.
Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 1993;5(2):254-8.