FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Frank Menniti

Research Profile

Living Beings

Chemicals & Drugs

Anatomy

Concepts & Ideas

Co-author Network

Publications

TOP 3
subramaniam uthayathas; Frank S Menniti; Christopher J Schmidt; Christopher L Shaffer; Stella M Papa
Assessment of adverse effects of neurotropic drugs in monkeys with the "Drug Effects on the Nervous System" (DENS) scale.
Stephen F Traynelis; Lonnie P Wollmuth; Chris J McBain; Frank S Menniti; Katie M Vance; Kevin K Ogden; Kasper B Hansen; Hongjie Yuan; Scott J Myers; ray dingledine
Glutamate receptor ion channels: structure, regulation, and function.
Carmela Giampà; Daunia Laurenti; Serenella Anzilotti; Giorgio Bernardi; Frank S Menniti; Francesca R Fusco
Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Frank Menniti (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: subramaniam uthayathas; Frank S Menniti; Christopher J Schmidt; Christopher L Shaffer; Stella M Papa
Assessment of adverse effects of neurotropic drugs in monkeys with the "Drug Effects on the Nervous System" (DENS) scale.
Journal of neuroscience methods 2013;215(1):97-102.
2010: Stephen F Traynelis; Lonnie P Wollmuth; Chris J McBain; Frank S Menniti; Katie M Vance; Kevin K Ogden; Kasper B Hansen; Hongjie Yuan; Scott J Myers; ray dingledine
Glutamate receptor ion channels: structure, regulation, and function.
Pharmacological reviews 2010;62(3):405-96.
2010: Carmela Giampà; Daunia Laurenti; Serenella Anzilotti; Giorgio Bernardi; Frank S Menniti; Francesca R Fusco
Inhibition of the striatal specific phosphodiesterase PDE10A ameliorates striatal and cortical pathology in R6/2 mouse model of Huntington's disease.
PloS one 2010;5(10):e13417.
2009: Jayvardhan Pandit; Michael D Forman; Kimberly F Fennell; Keith S Dillman; Frank S Menniti
Mechanism for the allosteric regulation of phosphodiesterase 2A deduced from the X-ray structure of a near full-length construct.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(43):18225-30.
2009: Carmela Giampà; Stefano Patassini; Antonella Borreca; Daunia Laurenti; Fabrizia Marullo; Giorgio Bernardi; Frank S Menniti; Francesca R Fusco
Phosphodiesterase 10 inhibition reduces striatal excitotoxicity in the quinolinic acid model of Huntington's disease.
Neurobiology of disease 2009;34(3):450-6.
2009: Sarah Threlfell; Stephen Sammut; Frank S Menniti; Christopher J Schmidt; Anthony R West
Inhibition of Phosphodiesterase 10A Increases the Responsiveness of Striatal Projection Neurons to Cortical Stimulation.
The Journal of pharmacology and experimental therapeutics 2009;328(3):785-95.
2008: Sheldon H Preskorn; Bryan Baker; Sheela Kolluri; Frank S Menniti; Michael Krams; Jaren W Landen
An innovative design to establish proof of concept of the antidepressant effects of the NR2B subunit selective N-methyl-D-aspartate antagonist, CP-101,606, in patients with treatment-refractory major depressive disorder.
Journal of clinical psychopharmacology 2008;28(6):631-7.
2008: John G Nutt; Steven A Gunzler; Trish Kirchhoff; Penelope Hogarth; Jerry L Weaver; Michael Krams; Brenda Jamerson; Frank S Menniti; Jaren W Landen
Effects of a NR2B selective NMDA glutamate antagonist, CP-101,606, on dyskinesia and Parkinsonism.
Movement disorders : official journal of the Movement Disorder Society 2008;23(13):1860-6.
2008: Shenping Liu; Mahmoud N Mansour; Keith S Dillman; Jose R Perez; Dennis E Danley; Paul A Aeed; Samuel P Simons; Peter K LeMotte; Frank S Menniti
Structural basis for the catalytic mechanism of human phosphodiesterase 9.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(36):13309-14.
2008: Paola Conti; Samuele Joppolo di Ventimiglia; Andrea Pinto; Lucia Tamborini; Frank S Menniti; John T Lazzaro; Carlo De Micheli
Synthesis of novel pyrrolo[3,4-d]pyrazole-dicarboxylic acids and evaluation of their interaction with glutamate receptors.
Chemistry & biodiversity 2008;5(4):657-63.
2008: S Hossein Fatemi; David P King; Teri J Reutiman; Timothy D Folsom; Jessica A Laurence; Susanne Lee; Yu-Ti Fan; Sara A Paciga; Marco Conti; Frank S Menniti
PDE4B polymorphisms and decreased PDE4B expression are associated with schizophrenia.
Schizophrenia research 2008;101(1-3):36-49.
2007: Katherine L Nicholson; Robert S Mansbach; Frank S Menniti; Robert L Balster
The phencyclidine-like discriminative stimulus effects and reinforcing properties of the NR2B-selective N-methyl-D-aspartate antagonist CP-101 606 in rats and rhesus monkeys.
Behavioural pharmacology 2007;18(8):731-43.
2007: Xuebing Cao; Li Liang; John R Hadcock; Philip A Iredale; David A Griffith; Frank S Menniti; Stewart A Factor; J Timothy Greenamyre; Stella M Papa
Blockade of cannabinoid type 1 receptors augments the antiparkinsonian action of levodopa without affecting dyskinesias in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 2007;323(1):318-26.
2007: Marc Morissette; Sandra Jourdain; Sara Al Sweidi; Frank S Menniti; Andres D Ramirez; Thérèse Di Paolo
Role of estrogen receptors in neuroprotection by estradiol against MPTP toxicity.
Neuropharmacology 2007;52(7):1509-20.
2007: Thomas A Chappie; John M Humphrey; Martin P Allen; Kimberly G Estep; Carol B Fox; Lorraine A Lebel; Spiros Liras; Eric S Marr; Frank S Menniti; Jayvardhan Pandit; Christopher J Schmidt; Meihua Tu; Robert D Williams; Feng V Yang
Discovery of a series of 6,7-dimethoxy-4-pyrrolidylquinazoline PDE10A inhibitors.
Journal of medicinal chemistry 2007;50(2):182-5.
2007: Frank S Menniti; Thomas A Chappie; John M Humphrey; Christopher J Schmidt
Phosphodiesterase 10A inhibitors: a novel approach to the treatment of the symptoms of schizophrenia.
Current opinion in investigational drugs (London, England : 2000) 2007;8(1):54-9.
2006: Timothy M Coskran; Daniel Morton; Frank S Menniti; Wendy O Adamowicz; Robin J Kleiman; Anne M Ryan; Christine A Strick; Christopher J Schmidt; Diane T Stephenson
Immunohistochemical localization of phosphodiesterase 10A in multiple mammalian species.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(11):1205-13.
2006: Frank S Menniti; W Stephen Faraci; Christopher J Schmidt
Phosphodiesterases in the CNS: targets for drug development.
Nature reviews. Drug discovery 2006;5(8):660-70.
2006: Judith A Siuciak; Douglas S Chapin; John F Harms; Lorraine A Lebel; Sheryl A McCarthy; Leslie K Chambers; Alka Shrikhande; Stephen Wong; Frank S Menniti; Christopher J Schmidt
Inhibition of the striatum-enriched phosphodiesterase PDE10A: a novel approach to the treatment of psychosis.
Neuropharmacology 2006;51(2):386-96.
2006: Judith A Siuciak; Sheryl A McCarthy; Douglas S Chapin; Remie A Fujiwara; Larry C James; Robert D Williams; Jeffrey L Stock; John McNeish; Christine A Strick; Frank S Menniti; Christopher J Schmidt
Genetic deletion of the striatum-enriched phosphodiesterase PDE10A: evidence for altered striatal function.
Neuropharmacology 2006;51(2):374-85.
2006: Z Xie; W O Adamowicz; W D Eldred; A B Jakowski; R J Kleiman; D G Morton; D T Stephenson; Christine A Strick; Robert D Williams; Frank S Menniti
Cellular and subcellular localization of PDE10A, a striatum-enriched phosphodiesterase.
Neuroscience 2006;139(2):597-607.
2006: Maria Zappalà; Giovanna Postorino; Nicola Micale; Salvatore Caccamese; Nunziatina Parrinello; Giovanni Grazioso; Gabriella Roda; Frank S Menniti; Giovambattista De Sarro; Silvana Grasso
Synthesis, chiral resolution, and enantiopharmacology of a potent 2,3-benzodiazepine derivative as noncompetitive AMPA receptor antagonist.
Journal of medicinal chemistry 2006;49(2):575-81.
2006: Maria Zappalà; Alessia Pellicanò; Nicola Micale; Frank S Menniti; Guido Ferreri; Giovambattista De Sarro; Silvana Grasso; Carlo De Micheli
New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists.
Bioorganic & medicinal chemistry letters 2006;16(1):167-70.
2005: Victoria Balannik; Frank S Menniti; Ana V Paternain; Juan Lerma; Yael Stern-Bach
Molecular mechanism of AMPA receptor noncompetitive antagonism.
Neuron 2005;48(2):279-88.
2005: Nicola Micale; Maria Zappalà; Giuseppe Zuccalà; Frank S Menniti; Guido Ferreri; Giovambattista De Sarro; Silvana Grasso
Synthesis of 2-semicarbazonomethyl-4,5-methylenedioxyphenylacetic acids as anticonvulsant agents.
Farmaco (Società chimica italiana : 1989) 2005;60(3):231-5.
2004: Christopher J Helal; Mark A Sanner; Christopher B Cooper; Thomas Gant; Mavis Adam; John C Lucas; Zhijun Kang; Stanley Kupchinsky; Michael K Ahlijanian; Bonnie Tate; Frank S Menniti; Kristin Kelly; Marcia Peterson
Discovery and SAR of 2-aminothiazole inhibitors of cyclin-dependent kinase 5/p25 as a potential treatment for Alzheimer's disease.
Bioorganic & medicinal chemistry letters 2004;14(22):5521-5.
2003: Maria Zappalà; Silvana Grasso; Nicola Micale; Giuseppe Zuccalà; Frank S Menniti; Guido Ferreri; Giovambattista De Sarro; Carlo De Micheli
1-aryl-6,7-methylenedioxy-3H-quinazolin-4-ones as anticonvulsant agents.
Bioorganic & medicinal chemistry letters 2003;13(24):4427-30.
2003: Thomas F Seeger; Brenda Bartlett; Timothy M Coskran; Jeffrey S Culp; Larry C James; David L Krull; Jerry Lanfear; Anne M Ryan; Christopher J Schmidt; Christine A Strick; Alison H Varghese; Robert D Williams; Patricia G Wylie; Frank S Menniti
Immunohistochemical localization of PDE10A in the rat brain.
Brain research 2003;985(2):113-26.
2003: Andres D Ramirez; Stephen K-F Wong; Frank S Menniti
Pramipexole inhibits MPTP toxicity in mice by dopamine D3 receptor dependent and independent mechanisms.
European journal of pharmacology 2003;475(1-3):29-35.
2003: Andres D Ramirez; Xingrong Liu; Frank S Menniti
Repeated estradiol treatment prevents MPTP-induced dopamine depletion in male mice.
Neuroendocrinology 2003;77(4):223-31.
2003: Silvana Grasso; Nicola Micale; Maria Zappalà; Alessandro Galli; Chiara Costagli; Frank S Menniti; Carlo De Micheli
Characterization of the mechanism of anticonvulsant activity for a selected set of putative AMPA receptor antagonists.
Bioorganic & medicinal chemistry letters 2003;13(3):443-6.
2003: Frank S Menniti; Alistair M Buchan; Bertrand L Chenard; Donald J Critchett; Alan H Ganong; Victor Guanowsky; Patricia A Seymour; Willard M Welch
CP-465,022, a selective noncompetitive AMPA receptor antagonist, blocks AMPA receptors but is not neuroprotective in vivo.
Stroke; a journal of cerebral circulation 2003;34(1):171-6.
2002: JT Lazzaro; Ana V Paternain; Juan Lerma; Bertrand L Chenard; FE Ewing; J Huang; Willard M Welch; Alan H Ganong; Frank S Menniti
Functional characterization of CP-465,022, a selective, noncompetitive AMPA receptor antagonist.
Neuropharmacology 2002;42(2):143-53.
2001: Bertrand L Chenard; Willard M Welch; James F Blake; T W Butler; A Reinhold; FE Ewing; Frank S Menniti; MJ Pagnozzi
Quinazolin-4-one alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists: structure-activity relationship of the C-2 side chain tether.
Journal of medicinal chemistry 2001;44(11):1710-7.
2001: Willard M Welch; FE Ewing; J Huang; Frank S Menniti; MJ Pagnozzi; K Kelly; Patricia A Seymour; Victor Guanowsky; S Guhan; M R Guinn; D Critchett; JT Lazzaro; Alan H Ganong; K M DeVries; T L Staigers; Bertrand L Chenard
Atropisomeric quinazolin-4-one derivatives are potent noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists.
Bioorganic & medicinal chemistry letters 2001;11(2):177-81.
2000: Frank S Menniti; Bertrand L Chenard; M B Collins; M F Ducat; M L Elliott; FE Ewing; J I Huang; K A Kelly; JT Lazzaro; MJ Pagnozzi; James Weeks; Willard M Welch; W Frost White
Characterization of the binding site for a novel class of noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists.
Molecular pharmacology 2000;58(6):1310-7.
2000: Bertrand L Chenard; Frank S Menniti; MJ Pagnozzi; K D Shenk; FE Ewing; Willard M Welch
Methaqualone derivatives are potent noncompetitive AMPA receptor antagonists.
Bioorganic & medicinal chemistry letters 2000;10(11):1203-5.
2000: Kathy Steece-Collier; Leslie K Chambers; S S Jaw-Tsai; Frank S Menniti; J Timothy Greenamyre
Antiparkinsonian actions of CP-101,606, an antagonist of NR2B subunit-containing N-methyl-d-aspartate receptors.
Experimental neurology 2000;163(1):239-43.
2000: Frank S Menniti; MJ Pagnozzi; P Butler; Bertrand L Chenard; S S Jaw-Tsai; W Frost White
CP-101,606, an NR2B subunit selective NMDA receptor antagonist, inhibits NMDA and injury induced c-fos expression and cortical spreading depression in rodents.
Neuropharmacology 2000;39(7):1147-55.
1999: Bertrand L Chenard; Frank S Menniti
Antagonists selective for NMDA receptors containing the NR2B subunit.
Current pharmaceutical design 1999;5(5):381-404.
1998: T W Butler; James F Blake; Jon Bordner; P Butler; Bertrand L Chenard; M A Collins; Debra L DeCosta; M J Ducat; M E Eisenhard; Frank S Menniti; MJ Pagnozzi; S B Sands; B E Segelstein; W Volberg; W Frost White; D Zhao
(3R,4S)-3-[4-(4-fluorophenyl)-4-hydroxypiperidin-1-yl]chroman-4,7-diol: a conformationally restricted analogue of the NR2B subtype-selective NMDA antagonist (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidino)- 1-propanol.
Journal of medicinal chemistry 1998;41(7):1172-84.
1997: Frank S Menniti; Bertrand L Chenard; M Collins; M Ducat; I Shalaby; F White
CP-101,606, a potent neuroprotectant selective for forebrain neurons.
European journal of pharmacology 1997;331(2-3):117-26.