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Patrick Aebischer

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Elisa Dassie; Patrick Aebischer; Melissa R Andrews; Jean-Charles Bensadoun; Matthias Cacquevel; David R Howlett; Ishrut Hussain; Jill C Richardson; Bernard L Schneider; Maria Grazia Spillantini; Fred S Wouters; James W Fawcett
Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model.
P G Coune; M Craveiro; M N Gaugler; Vladimír Mlynárik; B L Schneider; Patrick Aebischer; Rolf Gruetter
An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker.
Bruno Fauvet; Patrick Aebischer; Mustafa T Ardah; Philippe Coune; Carole Desobry; Omar M A El-Agnaf; David Eliezer; Mohamed-Bilal Fares; Niels Lion; Eliezer Masliah; Martial K Mbefo; Sarah Michael; Darren J Moore; Michel Prudent; Bernard Schneider; Elpida Tsika; Hilal A Lashuel
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.

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2013: Elisa Dassie; Patrick Aebischer; Melissa R Andrews; Jean-Charles Bensadoun; Matthias Cacquevel; David R Howlett; Ishrut Hussain; Jill C Richardson; Bernard L Schneider; Maria Grazia Spillantini; Fred S Wouters; James W Fawcett
Focal expression of adeno-associated viral-mutant tau induces widespread impairment in an APP mouse model.
Neurobiology of aging 2013;34(5):1355-68.
2013: P G Coune; M Craveiro; M N Gaugler; Vladimír Mlynárik; B L Schneider; Patrick Aebischer; Rolf Gruetter
An in vivo ultrahigh field 14.1 T (1) H-MRS study on 6-OHDA and α-synuclein-based rat models of Parkinson's disease: GABA as an early disease marker.
NMR in biomedicine 2013;26(1):43-50.
2012: Bruno Fauvet; Patrick Aebischer; Mustafa T Ardah; Philippe Coune; Carole Desobry; Omar M A El-Agnaf; David Eliezer; Mohamed-Bilal Fares; Niels Lion; Eliezer Masliah; Martial K Mbefo; Sarah Michael; Darren J Moore; Michel Prudent; Bernard Schneider; Elpida Tsika; Hilal A Lashuel
α-Synuclein in central nervous system and from erythrocytes, mammalian cells, and Escherichia coli exists predominantly as disordered monomer.
The Journal of biological chemistry 2012;287(19):15345-64.
2012: Meret Nora Gaugler; Ozgur Genc; Graham W Knott; Safa Mohanna; Ralf Schneggenburger; Patrick Aebischer; Mustafa Taleb Ardah; Jean-Charles Bensadoun; Wojciech Bobela; Marco Cantoni; Omar M A El-Agnaf; Bernard L Schneider
Nigrostriatal overabundance of α-synuclein leads to decreased vesicle density and deficits in dopamine release that correlate with reduced motor activity.
Acta neuropathologica 2012;123(5):653-69.
2012: Philippe G Coune; Bernard L Schneider; Patrick Aebischer
Parkinson's disease: gene therapies.
Cold Spring Harbor perspectives in medicine 2012;2(4):a009431.
2012: Abid Oueslati; Katerina E Paleologou; Bernard L Schneider; Patrick Aebischer; Hilal A Lashuel
Mimicking phosphorylation at serine 87 inhibits the aggregation of human α-synuclein and protects against its toxicity in a rat model of Parkinson's disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(5):1536-44.
2012: Patrick Aebischer
Philanthropy: The price of charity.
Nature 2012;481(7381):260.
2012: Vladimír Mlynárik; Bernard L Schneider; Lili Sun-Reimer; Sharon Janssens; Hongxia Lei; Patrick Aebischer; Matthias Cacquevel; Cristina Cudalbu; Rolf Gruetter
Proton and phosphorus magnetic resonance spectroscopy of a mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2012;31 Suppl 3():S87-99.
2011: Chris Towne; Veronica Setola; Bernard L Schneider; Patrick Aebischer
Neuroprotection by gene therapy targeting mutant SOD1 in individual pools of motor neurons does not translate into therapeutic benefit in fALS mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(2):274-83.
2011: Julien Dusonchet; Olexiy Kochubey; Klodjan Stafa; Samuel M Young; Romain Zufferey; Darren J Moore; Bernard L Schneider; Patrick Aebischer
A rat model of progressive nigral neurodegeneration induced by the Parkinson's disease-associated G2019S mutation in LRRK2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2011;31(3):907-12.
2011: Osiris Marroquin Belaunzaran; Maria Isabel Cordero; Veronica Setola; Siro Bianchi; Carmela Galli; Nicolas Bouche; Vladimir Mlynarik; Rolf Gruetter; Carmen Sandi; Jean-Charles Bensadoun; Maurizio Molinari; Patrick Aebischer
Chronic delivery of antibody fragments using immunoisolated cell implants as a passive vaccination tool.
PloS one 2011;6(4):e18268.
2010: Katerina E Paleologou; Abid Oueslati; Gideon Shakked; Carla C Rospigliosi; Hai-Young Kim; Gonzalo R Lamberto; Claudio O Fernandez; Adrian Schmid; Fariba Chegini; Wei Ping Gai; Diego Chiappe; Marc Moniatte; Bernard L Schneider; Patrick Aebischer; David Eliezer; Markus Zweckstetter; Eliezer Masliah; Hilal A Lashuel
Phosphorylation at S87 is enhanced in synucleinopathies, inhibits alpha-synuclein oligomerization, and influences synuclein-membrane interactions.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(9):3184-98.
2010: L Duplan; Nathalie Bernard; Wilfrid Casseron; Keith Dudley; Eric Thouvenot; Jérôme Honnorat; Véronique Rogemond; Béatrice de Bovis; Patrick Aebischer; Philippe Marin; Cédric Raoul; Christopher E Henderson; Brigitte Pettmann
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(2):785-96.
2010: C Towne; Bernard L Schneider; D Kieran; D E Redmond; Patrick Aebischer
Efficient transduction of non-human primate motor neurons after intramuscular delivery of recombinant AAV serotype 6.
Gene therapy 2010;17(1):141-6.
2009: Marina E Emborg; Jeffrey Moirano; J Raschke; V Bondarenko; R Zufferey; S Peng; Allison D Ebert; V Joers; Ben Roitberg; James E Holden; J Koprich; Jack William Lipton; Jeffrey Kordower; Patrick Aebischer
Response of aged parkinsonian monkeys to in vivo gene transfer of GDNF.
Neurobiology of disease 2009;36(2):303-11.
2009: Ayse Ulusoy; Gurdal Sahin; Tomas Björklund; Patrick Aebischer; Deniz Kirik
Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(9):1574-84.
2009: Roberto Mastroeni; Jean-Charles Bensadoun; Delphine Charvin; Patrick Aebischer; Aurora Pujol; Cédric Raoul
Insulin-like growth factor-1 and neurotrophin-3 gene therapy prevents motor decline in an X-linked adrenoleukodystrophy mouse model.
Annals of neurology 2009;66(1):117-22.
2009: Samareh Azeredo da Silveira; Bernard L Schneider; Carmen Cifuentes-Diaz; Daniel Sage; Toufik Abbas-Terki; Takeshi Iwatsubo; Michaël Unser; Patrick Aebischer
Phosphorylation does not prompt, nor prevent, the formation of alpha-synuclein toxic species in a rat model of Parkinson's disease.
Human molecular genetics 2009;18(5):872-87.
2009: Chris Towne; Marie Pertin; Ahmed T Beggah; Patrick Aebischer; Isabelle Decosterd
Recombinant adeno-associated virus serotype 6 (rAAV2/6)-mediated gene transfer to nociceptive neurons through different routes of delivery.
Molecular pain 2009;5():52.
2009: Chris Towne; Patrick Aebischer
Lentiviral and adeno-associated vector-based therapy for motor neuron disease through RNAi.
Methods in molecular biology (Clifton, N.J.) 2009;555():87-108.
2008: Masatoshi Suzuki; Jacalyn McHugh; Craig Tork; Brandon Shelley; Antonio Hayes; Ilaria Bellantuono; Patrick Aebischer; Clive Svendsen
Direct muscle delivery of GDNF with human mesenchymal stem cells improves motor neuron survival and function in a rat model of familial ALS.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(12):2002-10.
2008: Heike Runne; Etienne Régulier; Alexandre Kuhn; Diana Zala; Ozgun Gokce; Valérie Perrin; Beate Sick; Patrick Aebischer; Nicole Deglon; Ruth Luthi-Carter
Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2008;28(39):9723-31.
2008: Christophe Lo Bianco; James Shorter; Etienne Régulier; Hilal Lashuel; Takeshi Iwatsubo; Susan Lindquist; Patrick Aebischer
Hsp104 antagonizes alpha-synuclein aggregation and reduces dopaminergic degeneration in a rat model of Parkinson disease.
The Journal of clinical investigation 2008;118(9):3087-97.
2008: Chris Towne; Cédric Raoul; Bernard L Schneider; Patrick Aebischer
Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(6):1018-25.
2008: Matthias Bauer; Jolanta Szulc; Morten Meyer; Charlotte Harken Jensen; Toufik Abbas Terki; Andrea Meixner; Norbert Kinkl; Thomas Gasser; Patrick Aebischer; Marius Ueffing
Delta-like 1 participates in the specification of ventral midbrain progenitor derived dopaminergic neurons.
Journal of neurochemistry 2008;104(4):1101-15.
2008: Bernard Schneider; Romain Zufferey; Patrick Aebischer
Viral vectors, animal models and new therapies for Parkinson's disease.
Parkinsonism & related disorders 2008;14 Suppl 2():S169-71.
2008: Marina E Emborg; Allison D Ebert; Jeffrey Moirano; Sun Peng; Masatoshi Suzuki; Elizabeth E Capowski; Valerie Joers; Ben Roitberg; Patrick Aebischer; Clive Svendsen
GDNF-secreting human neural progenitor cells increase tyrosine hydroxylase and VMAT2 expression in MPTP-treated cynomolgus monkeys.
Cell transplantation 2008;17(4):383-95.
2008: Jolanta Szulc; Patrick Aebischer
Conditional gene expression and knockdown using lentivirus vectors encoding shRNA.
Methods in molecular biology (Clifton, N.J.) 2008;434():291-309.
2007: Maciej Wiznerowicz; Johan Jakobsson; Jolanta Szulc; Shunyao Liao; Alexandra Quazzola; Friedrich Beermann; Patrick Aebischer; Didier Trono
The Kruppel-associated box repressor domain can trigger de novo promoter methylation during mouse early embryogenesis.
The Journal of biological chemistry 2007;282(47):34535-41.
2007: Patrick Aebischer; Ann C Kato
Playng defense against Lou Gehrig's disease.
Scientific American 2007;297(5):86-93.
2007: Stéphane Palfi; Emmanuel Brouillet; Béchir Jarraya; Jocelyne Bloch; Caroline Jan; Masahiro Shin; Françoise Condé; Xiao-Jiang Li; Patrick Aebischer; Philippe Hantraye; Nicole Deglon
Expression of mutated huntingtin fragment in the putamen is sufficient to produce abnormal movement in non-human primates.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(8):1444-51.
2007: Elizabeth E Capowski; Bernard L Schneider; Allison D Ebert; Corey Seehus; Jolanta Szulc; Romain Zufferey; Patrick Aebischer; Clive Svendsen
Lentiviral vector-mediated genetic modification of human neural progenitor cells for ex vivo gene therapy.
Journal of neuroscience methods 2007;163(2):338-49.
2007: Valérie Perrin; Etienne Régulier; Toufik Abbas-Terki; Raymonde Hassig; Emmanuel Brouillet; Patrick Aebischer; Ruth Luthi-Carter; Nicole Deglon
Neuroprotection by Hsp104 and Hsp27 in lentiviral-based rat models of Huntington's disease.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(5):903-11.
2007: Bernard L Schneider; Corey Seehus; Elizabeth E Capowski; Patrick Aebischer; Su-Chun Zhang; Clive Svendsen
Over-expression of alpha-synuclein in human neural progenitors leads to specific changes in fate and differentiation.
Human molecular genetics 2007;16(6):651-66.
2007: Masatoshi Suzuki; Jacalyn McHugh; Craig Tork; Brandon Shelley; Sandra M Klein; Patrick Aebischer; Clive Svendsen
GDNF secreting human neural progenitor cells protect dying motor neurons, but not their projection to muscle, in a rat model of familial ALS.
PloS one 2007;2(8):e689.
2006: Jean-Charles Bensadoun; Patrick Aebischer
Viral vectors as a tool to model and treat Parkinson's disease.
Wiener klinische Wochenschrift 2006;118(19-20):568-70.
2006: Margarita Arango; Sébastien Holbert; Diana Zala; Emmanuel Brouillet; James Pearson; Etienne Régulier; Ashwani Kumar Thakur; Patrick Aebischer; Ronald B. Wetzel; Nicole Deglon; Christian Néri
CA150 expression delays striatal cell death in overexpression and knock-in conditions for mutant huntingtin neurotoxicity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(17):4649-59.
2006: Cédric Raoul; Emmanuelle Buhler; C Sadeghi; A Jacquier; Patrick Aebischer; Brigitte Pettmann; Christopher E Henderson; Georg Haase
Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):6007-12.
2006: Ali Sajadi; Jean-Charles Bensadoun; Bernard L Schneider; Christophe Lo Bianco; Patrick Aebischer
Transient striatal delivery of GDNF via encapsulated cells leads to sustained behavioral improvement in a bilateral model of Parkinson disease.
Neurobiology of disease 2006;22(1):119-29.
2006: Soshana Behrstock; Allison D Ebert; Jacalyn McHugh; S Vosberg; J Moore; B Schneider; Elizabeth E Capowski; D Hei; Jeffrey Kordower; Patrick Aebischer; Clive Svendsen
Human neural progenitors deliver glial cell line-derived neurotrophic factor to parkinsonian rodents and aged primates.
Gene therapy 2006;13(5):379-88.
2006: Cédric Raoul; S D Barker; Patrick Aebischer
Viral-based modelling and correction of neurodegenerative diseases by RNA interference.
Gene therapy 2006;13(6):487-95.
2006: Raúl Pardo; emilie colin; Etienne Régulier; Patrick Aebischer; Nicole Deglon; Sandrine Humbert; Frédéric Saudou
Inhibition of calcineurin by FK506 protects against polyglutamine-huntingtin toxicity through an increase of huntingtin phosphorylation at S421.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(5):1635-45.
2006: Jolanta Szulc; Maciej Wiznerowicz; Marc-Olivier Sauvain; Didier Trono; Patrick Aebischer
A versatile tool for conditional gene expression and knockdown.
Nature methods 2006;3(2):109-16.
2006: William E Blanco-Bose; Bernard L Schneider; Patrick Aebischer
Inducing tolerance to a soluble foreign antigen by encapsulated cell transplants.
Molecular therapy : the journal of the American Society of Gene Therapy 2006;13(2):447-56.
2006: Jean-Luc Ridet; Jean-Charles Bensadoun; Nicole Deglon; Patrick Aebischer; Anne D Zurn
Lentivirus-mediated expression of glutathione peroxidase: neuroprotection in murine models of Parkinson's disease.
Neurobiology of disease 2006;21(1):29-34.
2005: Diana Zala; Alexandra Benchoua; Emmanuel Brouillet; Valérie Perrin; Marie-Claude Gaillard; Anne D Zurn; Patrick Aebischer; Nicole Deglon
Progressive and selective striatal degeneration in primary neuronal cultures using lentiviral vector coding for a mutant huntingtin fragment.
Neurobiology of disease 2005;20(3):785-98.
2005: Young-Hwan Ahn; Jean-Charles Bensadoun; Patrick Aebischer; Anne D Zurn; Ake Seiger; Anders Björklund; Olle Lindvall; Lars U Wahlberg; Patrik Brundin; Gabriele S Kaminski Schierle
Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor.
Brain research bulletin 2005;66(2):135-42.
2005: Ali Sajadi; Matthias Bauer; Beat Thöny; Patrick Aebischer
Long-term glial cell line-derived neurotrophic factor overexpression in the intact nigrostriatal system in rats leads to a decrease of dopamine and increase of tetrahydrobiopterin production.
Journal of neurochemistry 2005;93(6):1482-6.
2005: Sandra M Klein; Soshana Behrstock; Jacalyn McHugh; Kristin Hoffmann; Kyle Wallace; Masatoshi Suzuki; Patrick Aebischer; Clive Svendsen
GDNF delivery using human neural progenitor cells in a rat model of ALS.
Human gene therapy 2005;16(4):509-21.
2005: Cédric Raoul; Toufik Abbas-Terki; Jean-Charles Bensadoun; Sandrine Guillot; Georg Haase; Jolanta Szulc; Christopher E Henderson; Patrick Aebischer
Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.
Nature medicine 2005;11(4):423-8.
2005: emilie colin; Etienne Régulier; Valérie Perrin; Alexandra Dürr; Alexis Brice; Patrick Aebischer; Nicole Deglon; Sandrine Humbert; Frédéric Saudou
Akt is altered in an animal model of Huntington's disease and in patients.
The European journal of neuroscience 2005;21(6):1478-88.
2004: Christophe Lo Bianco; Bernard L Schneider; Matthias Bauer; Ali Sajadi; Alexis Brice; Takeshi Iwatsubo; Patrick Aebischer
Lentiviral vector delivery of parkin prevents dopaminergic degeneration in an alpha-synuclein rat model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(50):17510-5.
2004: Christophe Lo Bianco; Nicole Deglon; William F Pralong; Patrick Aebischer
Lentiviral nigral delivery of GDNF does not prevent neurodegeneration in a genetic rat model of Parkinson's disease.
Neurobiology of disease 2004;17(2):283-9.
2004: J Bloch; Anne-Catherine Bachoud-Lévi; Nicole Deglon; Jean-Pascal Lefaucheur; Laurence Winkel; Stéphane Palfi; Jean-Paul Nguyen; Catherine Bourdet; Véronique Gaura; Philippe Remy; Pierre Brugières; M-F Boisse; Sophie Baudic; Pierre Cesaro; Philippe Hantraye; Patrick Aebischer; Marc Peschanski
Neuroprotective gene therapy for Huntington's disease, using polymer-encapsulated cells engineered to secrete human ciliary neurotrophic factor: results of a phase I study.
Human gene therapy 2004;15(10):968-75.
2004: Frank Schwenter; Nicolas Bouche; William F Pralong; Patrick Aebischer
In vivo calcium deposition on polyvinyl alcohol matrix used in hollow fiber cell macroencapsulation devices.
Biomaterials 2004;25(17):3861-8.
2004: Frank Schwenter; Bernard L Schneider; William F Pralong; Nicole Deglon; Patrick Aebischer
Survival of encapsulated human primary fibroblasts and erythropoietin expression under xenogeneic conditions.
Human gene therapy 2004;15(7):669-80.
2004: Haruhiko Kishima; Thomas Poyot; Jocelyne Bloch; Julien Dauguet; Françoise Condé; Frédéric Dollé; Françoise Hinnen; William F Pralong; Stéphane Palfi; Nicole Deglon; Patrick Aebischer; Philippe Hantraye
Encapsulated GDNF-producing C2C12 cells for Parkinson's disease: a pre-clinical study in chronic MPTP-treated baboons.
Neurobiology of disease 2004;16(2):428-39.
2004: Sandrine Guillot; Mimoun Azzouz; Nicole Deglon; Anne D Zurn; Patrick Aebischer
Local GDNF expression mediated by lentiviral vector protects facial nerve motoneurons but not spinal motoneurons in SOD1(G93A) transgenic mice.
Neurobiology of disease 2004;16(1):139-49.
2004: Ali Sajadi; Bernard L Schneider; Patrick Aebischer
Wlds-mediated protection of dopaminergic fibers in an animal model of Parkinson disease.
Current biology : CB 2004;14(4):326-30.
2004: Etienne Régulier; Diana Zala; Patrick Aebischer; Nicole Deglon
Lentiviral-mediated gene transfer to model triplet repeat disorders.
Methods in molecular biology (Clifton, N.J.) 2004;277():199-213.
2004: Diana Zala; Jean-Charles Bensadoun; Luis de Almeida; Blair R Leavitt; Claire-Anne Gutekunst; Patrick Aebischer; Michael R Hayden; Nicole Deglon
Long-term lentiviral-mediated expression of ciliary neurotrophic factor in the striatum of Huntington's disease transgenic mice.
Experimental neurology 2004;185(1):26-35.
2003: Etienne Régulier; Yvon Trottier; Valérie Perrin; Patrick Aebischer; Nicole Deglon
Early and reversible neuropathology induced by tetracycline-regulated lentiviral overexpression of mutant huntingtin in rat striatum.
Human molecular genetics 2003;12(21):2827-36.
2003: Corinne Kostic; F Chiodini; P Salmon; M Wiznerowicz; Nicole Deglon; Dana Hornfeld; D Trono; Patrick Aebischer; Daniel F Schorderet; Francis L Munier; Yvan Arsenijevic
Activity analysis of housekeeping promoters using self-inactivating lentiviral vector delivery into the mouse retina.
Gene therapy 2003;10(9):818-21.
2003: Nicole Deglon; Vincent Aubert; François Spertini; Laurence Winkel; Patrick Aebischer
Presence of Gal-alpha1,3Gal epitope on xenogeneic lines: implications for cellular gene therapy based on the encapsulation technology.
Xenotransplantation 2003;10(3):204-13.
2003: Bernard L Schneider; Frank Schwenter; William F Pralong; Patrick Aebischer
Prevention of the initial host immuno-inflammatory response determines the long-term survival of encapsulated myoblasts genetically engineered for erythropoietin delivery.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(4):506-14.
2003: Frank Schwenter; Nicole Deglon; Patrick Aebischer
Optimization of human erythropoietin secretion from MLV-infected human primary fibroblasts used for encapsulated cell therapy.
The journal of gene medicine 2003;5(3):246-57.
2003: Bernard L Schneider; Patrick Aebischer
Cellular implants: pioneers in xenotransplantation?
Xenotransplantation 2003;10(2):96-7.
2003: Jean-Charles Bensadoun; Luis de Almeida; Eric G Fine; Jack L Tseng; Nicole Deglon; Patrick Aebischer
Comparative study of GDNF delivery systems for the CNS: polymer rods, encapsulated cells, and lentiviral vectors.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):107-15.
2002: Florian M Barras; Philippe Pasche; Nicolas Bouche; Patrick Aebischer; Anne D Zurn
Glial cell line-derived neurotrophic factor released by synthetic guidance channels promotes facial nerve regeneration in the rat.
Journal of neuroscience research 2002;70(6):746-55.
2002: Toufik Abbas-Terki; William E Blanco-Bose; Nicole Deglon; William F Pralong; Patrick Aebischer
Lentiviral-mediated RNA interference.
Human gene therapy 2002;13(18):2197-201.
2002: Etienne Régulier; Luis de Almeida; B Sommer; Patrick Aebischer; Nicole Deglon
Dose-dependent neuroprotective effect of ciliary neurotrophic factor delivered via tetracycline-regulated lentiviral vectors in the quinolinic acid rat model of Huntington's disease.
Human gene therapy 2002;13(16):1981-90.
2002: Christopher Rinsch; philippe Dupraz; Bernard L Schneider; Nicole Deglon; Patrick H Maxwell; Peter J Ratcliffe; Patrick Aebischer
Delivery of erythropoietin by encapsulated myoblasts in a genetic model of severe anemia.
Kidney international 2002;62(4):1395-401.
2002: Christophe Lo Bianco; J-L Ridet; Bernard L Schneider; Nicole Deglon; Patrick Aebischer
alpha -Synucleinopathy and selective dopaminergic neuron loss in a rat lentiviral-based model of Parkinson's disease.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(16):10813-8.
2002: Detlev Boison; Alexander Huber; Vivianne Padrun; Nicole Deglon; Patrick Aebischer; Hanns Möhler
Seizure suppression by adenosine-releasing cells is independent of seizure frequency.
Epilepsia 2002;43(8):788-96.
2002: Birgit Sommer; Christopher Rinsch; Emmanuel Payen; Bruno Dalle; Bernard Schneider; Nicole Deglon; Annie Henri; Yves Beuzard; Patrick Aebischer
Long-term doxycycline-regulated secretion of erythropoietin by encapsulated myoblasts.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;6(2):155-61.
2002: Marcus Pericin; Alana Althage; Stefan Freigang; Hans Hengartner; Eric Rolland; philippe Dupraz; Bernard Thorens; Patrick Aebischer; Rolf M Zinkernagel
Allogeneic beta-islet cells correct diabetes and resist immune rejection.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8203-6.
2002: Luis de Almeida; Christopher A Ross; Diana Zala; Patrick Aebischer; Nicole Deglon
Lentiviral-mediated delivery of mutant huntingtin in the striatum of rats induces a selective neuropathology modulated by polyglutamine repeat size, huntingtin expression levels, and protein length.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(9):3473-83.
2002: Eric G Fine; Isabelle Decosterd; Michael Papaloïzos; Anne D Zurn; Patrick Aebischer
GDNF and NGF released by synthetic guidance channels support sciatic nerve regeneration across a long gap.
The European journal of neuroscience 2002;15(4):589-601.
2002: Nicole Deglon; Patrick Aebischer
Lentiviruses as vectors for CNS diseases.
Current topics in microbiology and immunology 2002;261():191-209.
2001: Jean-Charles Bensadoun; Luis de Almeida; M Dréano; Patrick Aebischer; Nicole Deglon
Neuroprotective effect of interleukin-6 and IL6/IL6R chimera in the quinolinic acid rat model of Huntington's syndrome.
The European journal of neuroscience 2001;14(11):1753-61.
2001: J Bloch; Eric G Fine; Nicolas Bouche; Anne D Zurn; Patrick Aebischer
Nerve growth factor- and neurotrophin-3-releasing guidance channels promote regeneration of the transected rat dorsal root.
Experimental neurology 2001;172(2):425-32.
2001: Anne D Zurn; Hans R Widmer; Patrick Aebischer
Sustained delivery of GDNF: towards a treatment for Parkinson's disease.
Brain research. Brain research reviews 2001;36(2-3):222-9.
2001: Yvan Arsenijevic; S Weiss; B Schneider; Patrick Aebischer
Insulin-like growth factor-I is necessary for neural stem cell proliferation and demonstrates distinct actions of epidermal growth factor and fibroblast growth factor-2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(18):7194-202.
2001: Patrick Aebischer; Jean-Luc Ridet
Recombinant proteins for neurodegenerative diseases: the delivery issue.
Trends in neurosciences 2001;24(9):533-40.
2001: Yvan Arsenijevic; Jean-Guy Villemure; Jean-François Brunet; J J Bloch; Nicole Deglon; Corinne Kostic; Anne D Zurn; Patrick Aebischer
Isolation of multipotent neural precursors residing in the cortex of the adult human brain.
Experimental neurology 2001;170(1):48-62.
2001: Alexander Huber; Vivianne Padrun; Nicole Deglon; Patrick Aebischer; Hanns Möhler; Detlev Boison
Grafts of adenosine-releasing cells suppress seizures in kindling epilepsy.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7611-6.
2001: Luis de Almeida; Diana Zala; Patrick Aebischer; Nicole Deglon
Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease.
Neurobiology of disease 2001;8(3):433-46.
2001: Christopher Rinsch; PD Quinodoz; Brigitte Pittet; Navid Alizadeh; Danielle Baetens; Denys Montandon; Patrick Aebischer; M S Pepper
Delivery of FGF-2 but not VEGF by encapsulated genetically engineered myoblasts improves survival and vascularization in a model of acute skin flap ischemia.
Gene therapy 2001;8(7):523-33.
2001: Christopher Rinsch; G Peduto; Bernard L Schneider; Patrick Aebischer
Inducing host acceptance to encapsulated xenogeneic myoblasts.
Transplantation 2001;71(3):345-51.
2001: Jack L Tseng; Patrick Aebischer
Encapsulated cell implants as a novel treatment for Parkinson's disease.
Methods in molecular medicine 2001;62():279-88.
2001: Bernard L Schneider; G Peduto; Patrick Aebischer
A self-immunomodulating myoblast cell line for erythropoietin delivery.
Gene therapy 2001;8(1):58-66.
2000: Anne-Catherine Bachoud-Lévi; Nicole Deglon; Jean-Paul Nguyen; J Bloch; Catherine Bourdet; Laurence Winkel; Philippe Rémy; M Goddard; Jean-Pascal Lefaucheur; Pierre Brugières; Sophie Baudic; Pierre Cesaro; Marc Peschanski; Patrick Aebischer
Neuroprotective gene therapy for Huntington's disease using a polymer encapsulated BHK cell line engineered to secrete human CNTF.
Human gene therapy 2000;11(12):1723-9.
2000: AF Hottinger; Mimoun Azzouz; Nicole Deglon; Patrick Aebischer; Anne D Zurn
Complete and long-term rescue of lesioned adult motoneurons by lentiviral-mediated expression of glial cell line-derived neurotrophic factor in the facial nucleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(15):5587-93.
2000: G Peduto; Christopher Rinsch; Bernard L Schneider; Eric Rolland; Patrick Aebischer
Long-term host unresponsiveness to encapsulated xenogeneic myoblasts after transient immunosuppression.
Transplantation 2000;70(1):78-85.
2000: Anne D Zurn; H Henry; Myriam Schluep; Vincent Aubert; Laurence Winkel; Barbara Eilers; C Bachmann; Patrick Aebischer
Evaluation of an intrathecal immune response in amyotrophic lateral sclerosis patients implanted with encapsulated genetically engineered xenogeneic cells.
Cell transplantation 2000;9(4):471-84.
2000: Jean-Charles Bensadoun; Nicole Deglon; Jack L Tseng; Jean-Luc Ridet; Anne D Zurn; Patrick Aebischer
Lentiviral vectors as a gene delivery system in the mouse midbrain: cellular and behavioral improvements in a 6-OHDA model of Parkinson's disease using GDNF.
Experimental neurology 2000;164(1):15-24.
2000: Vincent Mittoux; J M Joseph; F Conde; Stéphane Palfi; C Dautry; Thomas Poyot; Jocelyne Bloch; Nicole Deglon; Stéphane Ouary; E A Nimchinsky; Emmanuel Brouillet; Patrick R Hof; Marc Peschanski; Patrick Aebischer; Philippe Hantraye
Restoration of cognitive and motor functions by ciliary neurotrophic factor in a primate model of Huntington's disease.
Human gene therapy 2000;11(8):1177-87.
2000: C Cisterni; Christopher E Henderson; Patrick Aebischer; Brigitte Pettmann; Nicole Deglon
Efficient gene transfer and expression of biologically active glial cell line-derived neurotrophic factor in rat motoneurons transduced wit lentiviral vectors.
Journal of neurochemistry 2000;74(5):1820-8.
2000: Mimoun Azzouz; AF Hottinger; Jean-Charles Paterna; Anne D Zurn; Patrick Aebischer; Hansruedi Büeler
Increased motoneuron survival and improved neuromuscular function in transgenic ALS mice after intraspinal injection of an adeno-associated virus encoding Bcl-2.
Human molecular genetics 2000;9(5):803-11.
2000: Jack L Tseng; Patrick Aebischer
Encapsulated neural transplants.
Progress in brain research 2000;127():189-202.
2000: Jean-Luc Ridet; Nicole Deglon; Patrick Aebischer
Gene transfer techniques for the delivery of GDNF in Parkinson's disease.
Novartis Foundation symposium 2000;231():202-15; discussion 215-9, 302-6.
2000: Nicole Deglon; Jack L Tseng; Jean-Charles Bensadoun; Anne D Zurn; Yvan Arsenijevic; Luis de Almeida; R Zufferey; Didier Trono; Patrick Aebischer
Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease.
Human gene therapy 2000;11(1):179-90.
1999: Jean-William Fitting; R Paillex; Lorenz Hirt; Patrick Aebischer; Myriam Schluep
Sniff nasal pressure: a sensitive respiratory test to assess progression of amyotrophic lateral sclerosis.
Annals of neurology 1999;46(6):887-93.
1999: Christopher Rinsch; Bernard L Schneider; Patrick Aebischer
Highlights of the cell transplantation meeting at Montreux, March 1999.
Cell transplantation 1999;8(6):571-6.
1999: Patrick Aebischer; AF Hottinger; Nicole Deglon
Cellular xenotransplantation.
Nature medicine 1999;5(8):852.
1999: Bruno Dalle; Emmanuel Payen; E Regulier; Nicole Deglon; Philippe Rouyer-Fessard; Yves Beuzard; Patrick Aebischer
Improvement of mouse beta-thalassemia upon erythropoietin delivery by encapsulated myoblasts.
Gene therapy 1999;6(2):157-61.
1999: AF Hottinger; Patrick Aebischer
Treatment of diseases of the central nervous system using encapsulated cells.
Advances and technical standards in neurosurgery 1999;25():3-20.
1998: M Borkenhagen; R C Stoll; Peter Neuenschwander; Ulrich W Suter; Patrick Aebischer
In vivo performance of a new biodegradable polyester urethane system used as a nerve guidance channel.
Biomaterials 1998;19(23):2155-65.
1998: Jean-Charles Bensadoun; O Mirochnitchenko; M Inouye; Patrick Aebischer; Anne D Zurn
Attenuation of 6-OHDA-induced neurotoxicity in glutathione peroxidase transgenic mice.
The European journal of neuroscience 1998;10(10):3231-6.
1998: Etienne Régulier; Bernard L Schneider; Nicole Deglon; Yves Beuzard; Patrick Aebischer
Continuous delivery of human and mouse erythropoietin in mice by genetically engineered polymer encapsulated myoblasts.
Gene therapy 1998;5(8):1014-22.
1998: M Borkenhagen; J F Clémence; H Sigrist; Patrick Aebischer
Three-dimensional extracellular matrix engineering in the nervous system.
Journal of biomedical materials research 1998;40(3):392-400.
1998: Jack L Tseng; S L Bruhn; Anne D Zurn; Patrick Aebischer
Neurturin protects dopaminergic neurons following medial forebrain bundle axotomy.
Neuroreport 1998;9(8):1817-22.
1998: Jürgen Sautter; Jack L Tseng; D Braguglia; Patrick Aebischer; Christian Spenger; Rolf W Seiler; Hans R Widmer; Anne D Zurn
Implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor improve survival, growth, and function of fetal dopaminergic grafts.
Experimental neurology 1998;149(1):230-6.
1998: Anne D Zurn; Jack L Tseng; Nicole Deglon; J M Joseph; Patrick Aebischer
A gene therapy approach for the treatment of amyotrophic lateral sclerosis and Parkinson's disease.
Advances in pharmacology (San Diego, Calif.) 1998;42():929-31.
1997: Christopher Rinsch; Etienne Régulier; Nicole Deglon; Bruno Dalle; Yves Beuzard; Patrick Aebischer
A gene therapy approach to regulated delivery of erythropoietin as a function of oxygen tension.
Human gene therapy 1997;8(16):1881-9.
1997: AF Hottinger; Eric G Fine; M E Gurney; Anne D Zurn; Patrick Aebischer
The copper chelator d-penicillamine delays onset of disease and extends survival in a transgenic mouse model of familial amyotrophic lateral sclerosis.
The European journal of neuroscience 1997;9(7):1548-51.
1997: N A Pochon; A Menoud; Jack L Tseng; Anne D Zurn; Patrick Aebischer
Neuronal GDNF expression in the adult rat nervous system identified by in situ hybridization.
The European journal of neuroscience 1997;9(3):463-71.
1997: Jack L Tseng; E E Baetge; Anne D Zurn; Patrick Aebischer
GDNF reduces drug-induced rotational behavior after medial forebrain bundle transection by a mechanism not involving striatal dopamine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(1):325-33.
1996: Nicole Deglon; B Heyd; S A Tan; J M Joseph; Anne D Zurn; Patrick Aebischer
Central nervous system delivery of recombinant ciliary neurotrophic factor by polymer encapsulated differentiated C2C12 myoblasts.
Human gene therapy 1996;7(17):2135-46.
1996: E Buchser; M Goddard; B Heyd; J M Joseph; J Favre; Nicolas de Tribolet; M Lysaght; Patrick Aebischer
Immunoisolated xenogenic chromaffin cell therapy for chronic pain. Initial clinical experience.
Anesthesiology 1996;85(5):1005-12; discussion 29A-30A.
1996: S A Tan; Nicole Deglon; Anne D Zurn; E E Baetge; B Bamber; Ann C Kato; Patrick Aebischer
Rescue of motoneurons from axotomy-induced cell death by polymer encapsulated cells genetically engineered to release CNTF.
Cell transplantation 1996;5(5):577-87.
1996: Patrick Aebischer; Myriam Schluep; Nicole Deglon; J M Joseph; Lorenz Hirt; B Heyd; M Goddard; J P Hammang; Anne D Zurn; Ann C Kato; F Regli; E E Baetge
Intrathecal delivery of CNTF using encapsulated genetically modified xenogeneic cells in amyotrophic lateral sclerosis patients.
Nature medicine 1996;2(6):696-9.
1996: Patrick Aebischer; N A Pochon; B Heyd; Nicole Deglon; J M Joseph; Anne D Zurn; E E Baetge; J P Hammang; M Goddard; M Lysaght; F Kaplan; Ann C Kato; Myriam Schluep; Lorenz Hirt; F Regli; François Porchet; Nicolas de Tribolet
Gene therapy for amyotrophic lateral sclerosis (ALS) using a polymer encapsulated xenogenic cell line engineered to secrete hCNTF.
Human gene therapy 1996;7(7):851-60.
1996: Anne D Zurn; L Winkel; A Menoud; Karima Djabali; Patrick Aebischer
Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro.
Journal of neuroscience research 1996;44(2):133-41.
1996: Y Sagot; S A Tan; J P Hammang; Patrick Aebischer; Ann C Kato
GDNF slows loss of motoneurons but not axonal degeneration or premature death of pmn/pmn mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(7):2335-41.
1996: Anne D Zurn; J Tseng; Patrick Aebischer
Treatment of Parkinson's disease. Symptomatic cell therapies: cells as biological minipumps.
European neurology 1996;36(6):405-8.
1996: S A Tan; Patrick Aebischer
The problems of delivering neuroactive molecules to the CNS.
Ciba Foundation symposium 1996;196():211-36; discussion 236-9.
1995: Y Sagot; Michel Dubois-Dauphin; S A Tan; Fabienne de Bilbao; Patrick Aebischer; Jean-Claude Martinou; Ann C Kato
Bcl-2 overexpression prevents motoneuron cell body loss but not axonal degeneration in a mouse model of a neurodegenerative disease.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(11):7727-33.
1995: X M Xu; V Guénard; Naomi Kleitman; Patrick Aebischer; Mary Bartlett Bunge
A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord.
Experimental neurology 1995;134(2):261-72.
1995: Ravi V Bellamkonda; J P Ranieri; Patrick Aebischer
Laminin oligopeptide derivatized agarose gels allow three-dimensional neurite extension in vitro.
Journal of neuroscience research 1995;41(4):501-9.
1995: J P Ranieri; Ravi V Bellamkonda; E J Bekos; T G Vargo; J A Gardella; Patrick Aebischer
Neuronal cell attachment to fluorinated ethylene propylene films with covalently immobilized laminin oligopeptides YIGSR and IKVAV. II.
Journal of biomedical materials research 1995;29(6):779-85.
1995: T G Vargo; E J Bekos; Y S Kim; J P Ranieri; Ravi V Bellamkonda; Patrick Aebischer; D E Margevich; P M Thompson; Frank V Bright; J A Gardella
Synthesis and characterization of fluoropolymeric substrata with immobilized minimal peptide sequences for cell adhesion studies. I.
Journal of biomedical materials research 1995;29(6):767-78.
1995: M Taborelli; L Eng; Pierre Descouts; J P Ranieri; Ravi V Bellamkonda; Patrick Aebischer
Bovine serum albumin conformation on methyl and amine functionalized surfaces compared by scanning force microscopy.
Journal of biomedical materials research 1995;29(6):707-14.
1995: Y Sagot; S A Tan; E Baetge; H Schmalbruch; Ann C Kato; Patrick Aebischer
Polymer encapsulated cell lines genetically engineered to release ciliary neurotrophic factor can slow down progressive motor neuronopathy in the mouse.
The European journal of neuroscience 1995;7(6):1313-22.
1995: Ravi V Bellamkonda; J P Ranieri; N Bouche; Patrick Aebischer
Hydrogel-based three-dimensional matrix for neural cells.
Journal of biomedical materials research 1995;29(5):663-71.
1995: Patrick Aebischer; Ann C Kato
Treatment of amyotrophic lateral sclerosis using a gene therapy approach.
European neurology 1995;35(2):65-8.
1995: P M Galletti; Patrick Aebischer; M J Lysaght
The dawn of biotechnology in artificial organs.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1995;41(1):49-57.
1994: Anne D Zurn; E E Baetge; J P Hammang; S A Tan; Patrick Aebischer
Glial cell line-derived neurotrophic factor (GDNF), a new neurotrophic factor for motoneurones.
Neuroreport 1994;6(1):113-8.
1994: Patrick Aebischer; E Buchser; J M Joseph; J Favre; N de Tribolet; M Lysaght; S Rudnick; M Goddard
Transplantation in humans of encapsulated xenogeneic cells without immunosuppression. A preliminary report.
Transplantation 1994;58(11):1275-7.
1994: J P Ranieri; Ravi V Bellamkonda; E J Bekos; J A Gardella; H J Mathieu; L Ruiz; Patrick Aebischer
Spatial control of neuronal cell attachment and differentiation on covalently patterned laminin oligopeptide substrates.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1994;12(8):725-35.
1994: B A Zielinski; Patrick Aebischer
Chitosan as a matrix for mammalian cell encapsulation.
Biomaterials 1994;15(13):1049-56.
1993: SA Makohliso; Robert F Valentini; Patrick Aebischer
Magnitude and polarity of a fluoroethylene propylene electret substrate charge influences neurite outgrowth in vitro.
Journal of biomedical materials research 1993;27(8):1075-85.
1993: J P Ranieri; Ravi V Bellamkonda; J Jacob; T G Vargo; J A Gardella; Patrick Aebischer
Selective neuronal cell attachment to a covalently patterned monoamine on fluorinated ethylene propylene films.
Journal of biomedical materials research 1993;27(7):917-25.
1993: Jacqueline Sagen; H Wang; P A Tresco; Patrick Aebischer
Transplants of immunologically isolated xenogeneic chromaffin cells provide a long-term source of pain-reducing neuroactive substances.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(6):2415-23.
1993: Robert F Valentini; T G Vargo; J A Gardella; Patrick Aebischer
Patterned neuronal attachment and outgrowth on surface modified, electrically charged fluoropolymer substrates.
Journal of biomaterials science. Polymer edition 1993;5(1-2):13-36.
1992: V Guénard; Naomi Kleitman; T K Morrissey; RP Bunge; Patrick Aebischer
Syngeneic Schwann cells derived from adult nerves seeded in semipermeable guidance channels enhance peripheral nerve regeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1992;12(9):3310-20.
1992: C B Jaeger; Patrick Aebischer; P A Tresco; Shelley R Winn; L A Greene
Growth of tumour cell lines in polymer capsules: ultrastructure of encapsulated PC12 cells.
Journal of neurocytology 1992;21(7):469-80.
1992: Shelley R Winn; P A Tresco; B Zielinski; Jacqueline Sagen; Patrick Aebischer
Microencapsulated bovine chromaffin cells in vitro: effect of density and coseeding with a NGF-releasing cell line.
Journal of neural transplantation & plasticity 1992;3(2-3):115-24.
1992: Robert F Valentini; T G Vargo; J A Gardella; Patrick Aebischer
Electrically charged polymeric substrates enhance nerve fibre outgrowth in vitro.
Biomaterials 1992;13(3):183-90.
1992: P A Tresco; Shelley R Winn; Patrick Aebischer
Polymer encapsulated neurotransmitter secreting cells. Potential treatment for Parkinson's disease.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1992;38(1):17-23.
1992: P A Tresco; Shelley R Winn; S Tan; C B Jaeger; L A Greene; Patrick Aebischer
Polymer-encapsulated PC12 cells: long-term survival and associated reduction in lesion-induced rotational behavior.
Cell transplantation 1992;1(2-3):255-64.
1991: E G Fine; Robert F Valentini; Ravi V Bellamkonda; Patrick Aebischer
Improved nerve regeneration through piezoelectric vinylidenefluoride-trifluoroethylene copolymer guidance channels.
Biomaterials 1991;12(8):775-80.
1991: Patrick Aebischer; P A Tresco; Jacqueline Sagen; Shelley R Winn
Transplantation of microencapsulated bovine chromaffin cells reduces lesion-induced rotational asymmetry in rats.
Brain research 1991;560(1-2):43-9.
1991: Shelley R Winn; P A Tresco; B Zielinski; L A Greene; C B Jaeger; Patrick Aebischer
Behavioral recovery following intrastriatal implantation of microencapsulated PC12 cells.
Experimental neurology 1991;113(3):322-9.
1991: L Christenson; L Wahlberg; Patrick Aebischer
Mast cells and tissue reaction to intraperitoneally implanted polymer capsules.
Journal of biomedical materials research 1991;25(9):1119-31.
1991: V Guénard; C A Dinarello; P J Weston; Patrick Aebischer
Peripheral nerve regeneration is impeded by interleukin-1 receptor antagonist released from a polymeric guidance channel.
Journal of neuroscience research 1991;29(3):396-400.
1991: C B Jaeger; Shelley R Winn; P A Tresco; Patrick Aebischer
Repair of the blood-brain barrier following implantation of polymer capsules.
Brain research 1991;551(1-2):163-70.
1991: Patrick Aebischer; Shelley R Winn; P A Tresco; C B Jaeger; L A Greene
Transplantation of polymer encapsulated neurotransmitter secreting cells: effect of the encapsulation technique.
Journal of biomechanical engineering 1991;113(2):178-83.
1991: Patrick Aebischer; P E Lacy; A Gerasimidi-Vazeou; V Hauptfeld
Production of marked prolongation of islet xenograft survival (rat to mouse) by local release of mouse and rat antilymphocyte sera at transplant site.
Diabetes 1991;40(4):482-5.
1991: Patrick Aebischer; P A Tresco; Shelley R Winn; L A Greene; C B Jaeger
Long-term cross-species brain transplantation of a polymer-encapsulated dopamine-secreting cell line.
Experimental neurology 1991;111(3):269-75.
1991: V Guénard; Robert F Valentini; Patrick Aebischer
Influence of surface texture of polymeric sheets on peripheral nerve regeneration in a two-compartment guidance system.
Biomaterials 1991;12(2):259-63.
1991: Patrick Aebischer; L Wahlberg; P A Tresco; Shelley R Winn
Macroencapsulation of dopamine-secreting cells by coextrusion with an organic polymer solution.
Biomaterials 1991;12(1):50-6.
1990: Patrick Aebischer; V Guénard; Robert F Valentini
The morphology of regenerating peripheral nerves is modulated by the surface microgeometry of polymeric guidance channels.
Brain research 1990;531(1-2):211-8.
1990: H Uludag; T K Ip; Patrick Aebischer
Transport functions in a bioartificial kidney under uremic conditions.
The International journal of artificial organs 1990;13(2):93-7.
1990: T K Ip; P M Galletti; Patrick Aebischer
Effects of attachment substrates on the growth and differentiation of LLC-PK1 cells.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1990;26(2):162-8.
1990: C B Jaeger; L A Greene; P A Tresco; Shelley R Winn; Patrick Aebischer
Polymer encapsulated dopaminergic cell lines as "alternative neural grafts".
Progress in brain research 1990;82():41-6.
1989: Patrick Aebischer; V Guénard; S Brace
Peripheral nerve regeneration through blind-ended semipermeable guidance channels: effect of the molecular weight cutoff.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1989;9(10):3590-5.
1989: Shelley R Winn; L Wahlberg; P A Tresco; Patrick Aebischer
An encapsulated dopamine-releasing polymer alleviates experimental parkinsonism in rats.
Experimental neurology 1989;105(3):244-50.
1989: Patrick Aebischer; A N Salessiotis; Shelley R Winn
Basic fibroblast growth factor released from synthetic guidance channels facilitates peripheral nerve regeneration across long nerve gaps.
Journal of neuroscience research 1989;23(3):282-9.
1989: L Christenson; Patrick Aebischer; P McMillan; P M Galletti
Tissue reaction to intraperitoneal polymer implants: species difference and effects of corticoid and doxorubicin.
Journal of biomedical materials research 1989;23(7):705-18.
1989: H Uludag; G Panol; Patrick Aebischer
Control of water flux in a bioartificial kidney.
ASAIO transactions / American Society for Artificial Internal Organs 1989;35(3):523-7.
1989: Robert F Valentini; Angelo M Sabatini; Paolo Dario; Patrick Aebischer
Polymer electret guidance channels enhance peripheral nerve regeneration in mice.
Brain research 1989;480(1-2):300-4.
1989: Shelley R Winn; Patrick Aebischer; P M Galletti
Brain tissue reaction to permselective polymer capsules.
Journal of biomedical materials research 1989;23(1):31-44.
1988: L Christenson; Patrick Aebischer; P M Galletti
Encapsulated thymic epithelial cells as a potential treatment for immunodeficiencies.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(3):681-6.
1988: T K Ip; Patrick Aebischer; P M Galletti
Cellular control of membrane permeability. Implications for a bioartificial renal tubule.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(3):351-5.
1988: Patrick Aebischer; V Guénard; Shelley R Winn; Robert F Valentini; P M Galletti
Blind-ended semipermeable guidance channels support peripheral nerve regeneration in the absence of a distal nerve stump.
Brain research 1988;454(1-2):179-87.
1988: Patrick Aebischer; Shelley R Winn; P M Galletti
Transplantation of neural tissue in polymer capsules.
Brain research 1988;448(2):364-8.
1988: P M Galletti; Patrick Aebischer; H F Sasken; M B Goddard; T H Chiu
Experience with fully bioresorbable aortic grafts in the dog.
Surgery 1988;103(2):231-41.
1988: Patrick Aebischer; R F Valentini; Shelley R Winn; P M Galletti
The use of a semi-permeable tube as a guidance channel for a transected rabbit optic nerve.
Progress in brain research 1988;78():599-603.
1988: Patrick Aebischer; M B Goddard; H F Sasken; T J Hunter; P M Galletti
Tissue reaction to fabrics coated with turbostratic carbon: subcutaneous versus vascular implants.
Biomaterials 1988;9(1):80-5.
1987: Patrick Aebischer; Robert F Valentini; Paolo Dario; C Domenici; P M Galletti
Piezoelectric guidance channels enhance regeneration in the mouse sciatic nerve after axotomy.
Brain research 1987;436(1):165-8.
1987: Robert F Valentini; Patrick Aebischer; Shelley R Winn; P M Galletti
Collagen- and laminin-containing gels impede peripheral nerve regeneration through semipermeable nerve guidance channels.
Experimental neurology 1987;98(2):350-6.
1987: Patrick Aebischer; T K Ip; L Miracoli; P M Galletti
Renal epithelial cells grown on semipermeable hollow fibers as a potential ultrafiltrate processor.
ASAIO transactions / American Society for Artificial Internal Organs 1987;33(3):96-102.
1987: Patrick Aebischer; Robert F Valentini; Paolo Dario; C Domenici; V Guénard; Shelley R Winn; P M Galletti
Piezoelectric nerve guidance channels enhance peripheral nerve regeneration.
ASAIO transactions / American Society for Artificial Internal Organs 1987;33(3):456-8.
1987: Patrick Aebischer; T K Ip; G Panol; P M Galletti
The bioartificial kidney: progress towards an ultrafiltration device with renal epithelial cells processing.
Life support systems : the journal of the European Society for Artificial Organs 1987;5(2):159-68.
1986: Patrick Aebischer; Robert F Valentini; Shelley R Winn; S Kunz; H Sasken; P M Galletti
Regeneration of transected sciatic nerves through semi-permeable nerve guidance channels. Effects of extracellular matrix protein additives.
ASAIO transactions / American Society for Artificial Internal Organs 1986;32(1):474-7.
1986: P D Richardson; H Sasken; A Parhizgar; Patrick Aebischer; G Panol; T H Chiu; P M Galletti
Tissue developed around bioresorbable implants. Load-bearing versus histology.
ASAIO transactions / American Society for Artificial Internal Organs 1986;32(1):342-5.
1986: Patrick Aebischer; P C Russell; L Christenson; G Panol; J M Monchik; P M Galletti
A bioartificial parathyroid.
ASAIO transactions / American Society for Artificial Internal Organs 1986;32(1):134-7.
1986: Patrick Aebischer; G Panol; P M Galletti
An intraperitoneal receptacle for macroencapsulated endocrine tissue.
ASAIO transactions / American Society for Artificial Internal Organs 1986;32(1):130-3.
1985: P M Galletti; L A Trudell; T H Chiu; H Sasken; P D Richardson; A Parhizgar; Patrick Aebischer
Coated bioresorbable mesh as vascular graft material.
Transactions - American Society for Artificial Internal Organs 1985;31():257-63.