FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Irmgard Merfort

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Jurkat Cells

Genes & Molecular Sequences

Molecular Structure

Concepts & Ideas

Procedures

Phytotherapy

Co-author Network

Publications

TOP 3
Mathias Könczöl; Irmgard Merfort; Manuel Garcia-Käufer; Reto Gieré; Richard Gminski; Evi Stangenberg; Adilka Weiss; Volker Mersch-Sundermann
Cell-cycle changes and oxidative stress response to magnetite in a549 human lung cells.
Mathias Könczöl; Irmgard Merfort; Richard Gminski; Adilka Weiß; Volker Mersch-Sundermann
Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 lung cells.
Carsten Gründemann; Manuel Garcia-Käufer; Mathias Könczöl; Irmgard Merfort; Barbara Sauer; Evi Stangenberg; Martin Zehl; Roman Huber
Traditionally used Veronica officinalis inhibits proinflammatory mediators via the NF-κB signalling pathway in a human lung cell line.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Irmgard Merfort (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Mathias Könczöl; Irmgard Merfort; Manuel Garcia-Käufer; Reto Gieré; Richard Gminski; Evi Stangenberg; Adilka Weiss; Volker Mersch-Sundermann
Cell-cycle changes and oxidative stress response to magnetite in a549 human lung cells.
Chemical research in toxicology 2013;26(5):693-702.
2013: Mathias Könczöl; Irmgard Merfort; Richard Gminski; Adilka Weiß; Volker Mersch-Sundermann
Oxidative stress and inflammatory response to printer toner particles in human epithelial A549 lung cells.
Toxicology letters 2013;216(2-3):171-80.
2013: Carsten Gründemann; Manuel Garcia-Käufer; Mathias Könczöl; Irmgard Merfort; Barbara Sauer; Evi Stangenberg; Martin Zehl; Roman Huber
Traditionally used Veronica officinalis inhibits proinflammatory mediators via the NF-κB signalling pathway in a human lung cell line.
Journal of ethnopharmacology 2013;145(1):118-26.
2012: Mathias Könczöl; Irmgard Merfort; Barbara Rothen-Rutishauser; Bianca Schäfer; Sandra Ebeling; Manuel Garcia-Käufer; Reto Gieré; Richard Gminski; Ella Goldenberg; Bernard Grobéty; Volker Mersch-Sundermann
Cellular uptake and toxic effects of fine and ultrafine metal-sulfate particles in human A549 lung epithelial cells.
Chemical research in toxicology 2012;25(12):2687-703.
2012: Katrin Naumann; Kathrin Schmich; Christoph Jaeger; Felix Kratz; Irmgard Merfort
Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines.
Anti-cancer drugs 2012;23(6):614-26.
2012: Marcio Fronza; Stefan Günther; Berta Heinzmann; Evelyn Lamy; Stefan Laufer; Irmgard Merfort
Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action.
Phytochemistry 2012;78():107-19.
2012: Torsten Lingott; Irmgard Merfort; Thomas Steinbrecher
Free energy calculations on snake venom metalloproteinase BaP1.
Chemical biology & drug design 2012;79(6):990-1000.
2012: Agnès Millet; Florian Stintzing; Daniel Jonas; Evelyn Lamy; Volker Mersch-Sundermann; Irmgard Merfort
Fermentation enhances the biological activity of Allium cepa bulb extracts.
Journal of agricultural and food chemistry 2012;60(9):2148-56.
2012: Christian Senger; Irmgard Merfort; Hitesh Patel; Kersten Döring; Anika Erxleben; Stephan Flemming; Björn A Grüning; Stefan Günther
Mining and evaluation of molecular relationships in literature.
Bioinformatics (Oxford, England) 2012;28(5):709-14.
2011: Irmgard Merfort
Perspectives on sesquiterpene lactones in inflammation and cancer.
Current drug targets 2011;12(11):1560-73.
2011: Mathias Könczöl; Irmgard Merfort; Barbara Rothen-Rutishauser; Fabian Treude; Sandra Ebeling; Reto Gieré; Richard Gminski; Ella Goldenberg; Bernard Grobéty; Volker Mersch-Sundermann
Cytotoxicity and genotoxicity of size-fractionated iron oxide (magnetite) in A549 human lung epithelial cells: role of ROS, JNK, and NF-κB.
Chemical research in toxicology 2011;24(9):1460-75.
2011: M Fronza; M Hamburger; B Heinzmann; S Laufer; Renato Murillo; S Ślusarczyk; M Adams; Irmgard Merfort
In vitro cytotoxic activity of abietane diterpenes from Peltodon longipes as well as Salvia miltiorrhiza and Salvia sahendica.
Bioorganic & medicinal chemistry 2011;19(16):4876-81.
2011: Cleber A Schmidt; Victor Wray; Berta Heinzmann; Stefan Laufer; Renato Murillo; Irmgard Merfort
Structural and conformational analysis of proanthocyanidins from Parapiptadenia rigida and their wound-healing properties.
Journal of natural products 2011;74(6):1427-36.
2011: Ivan Vucković; Ljubodrag Vujisić; Christoph A Klaas; Irmgard Merfort; Slobodan Milosavljević
NF-κB DNA binding activity of sesquiterpene lactones from Anthemis arvensis and Anthemis cotula.
Natural product research 2011;25(8):800-5.
2011: Eun Myoung Shin; Sanghee Kim; Irmgard Merfort; Yeong Shik Kim
Glycyrol induces apoptosis in human Jurkat T cell lymphocytes via the Fas-FasL/caspase-8 pathway.
Planta medica 2011;77(3):242-7.
2011: Rebekka Schlatter; Kathrin Schmich; Anna Lutz; Judith Trefzger; Oliver Sawodny; Michael Ederer; Irmgard Merfort
Modeling the TNFα-induced apoptosis pathway in hepatocytes.
PloS one 2011;6(4):e18646.
2011: Kathrin Schmich; Rebekka Schlatter; Nadia Corazza; Karine Sá Ferreira; Michael Ederer; Thomas Brunner; Christoph Borner; Irmgard Merfort
Tumor necrosis factor α sensitizes primary murine hepatocytes to Fas/CD95-induced apoptosis in a Bim- and Bid-dependent manner.
Hepatology (Baltimore, Md.) 2011;53(1):282-92.
2010: Cleber A Schmidt; Renato Murillo; Torsten Bruhn; Gerhard Bringmann; Marcia Goettert; Berta Heinzmann; Volker Brecht; Stefan A Laufer; Irmgard Merfort
Catechin derivatives from Parapiptadenia rigida with in vitro wound-healing properties.
Journal of natural products 2010;73(12):2035-41.
2010: Márcia Goettert; Verena Schattel; Pierre Koch; Irmgard Merfort; Stefan Laufer
Biological evaluation and structural determinants of p38α mitogen-activated-protein kinase and c-Jun-N-terminal kinase 3 inhibition by flavonoids.
Chembiochem : a European journal of chemical biology 2010;11(18):2579-88.
2010: Sebastian Zellmer; Wolfgang Schmidt-Heck; Patricio Godoy; Honglei Weng; Christoph Meyer; Thomas Lehmann; Titus Sparna; Wiebke Schormann; Seddik Hammad; Clemens Kreutz; Jens Timmer; Fritz von Weizsäcker; Petra A Thürmann; Irmgard Merfort; Reinhard Guthke; Steven Dooley; Jan G Hengstler; Rolf Gebhardt
Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes.
Hepatology (Baltimore, Md.) 2010;52(6):2127-36.
2010: Christian Lass; Irmgard Merfort; Stefan F Martin
In vitro and in vivo analysis of pro- and anti-inflammatory effects of weak and strong contact allergens.
Experimental dermatology 2010;19(11):1007-13.
2010: Agnès Millet; Florian Stintzing; Irmgard Merfort
Flavonol quantification and stability of phenolics in fermented extracts from fresh Betula pendula leaves.
Journal of pharmaceutical and biomedical analysis 2010;53(2):137-44.
2010: Zhi Li; Irmgard Merfort; Eike Reich
High-performance thin layer chromatography for quality control of multicomponent herbal drugs: example of cangzhu xianglian san.
Journal of AOAC International 2010;93(5):1390-8.
2010: Hannes G Wallnoefer; Torsten Lingott; José María Gutiérrez; Irmgard Merfort; Klaus Liedl
Backbone flexibility controls the activity and specificity of a protein-protein interface: specificity in snake venom metalloproteases.
Journal of the American Chemical Society 2010;132(30):10330-7.
2010: U Woelfle; Birgit Simon-Haarhaus; Irmgard Merfort; Christoph M Schempp
Reseda luteola L. extract displays antiproliferative and pro-apoptotic activities that are related to its major flavonoids.
Phytotherapy research : PTR 2010;24(7):1033-6.
2010: Berthold Büchele; Waltraud Zugmaier; Oleg Lunov; Tatiana Syrovets; Irmgard Merfort; Thomas Simmet
Surface plasmon resonance analysis of nuclear factor-kappaB protein interactions with the sesquiterpene lactone helenalin.
Analytical biochemistry 2010;401(1):30-7.
2010: Eun Myoung Shin; Hong Yu Zhou; Guang Hua Xu; Seung Ho Lee; Irmgard Merfort; Yeong Shik Kim
Anti-inflammatory activity of hispidol A 25-methyl ether, a triterpenoid isolated from Ponciri Immaturus Fructus.
European journal of pharmacology 2010;627(1-3):318-24.
2010: José M Escandell; M Carmen Recio; Rosa M Giner; Salvador Máñez; Miguel Cerdá-Nicolás; Irmgard Merfort; José-Luis Ríos
Inhibition of delayed-type hypersensitivity by Cucurbitacin R through the curbing of lymphocyte proliferation and cytokine expression by means of nuclear factor AT translocation to the nucleus.
The Journal of pharmacology and experimental therapeutics 2010;332(2):352-63.
2010: Juliane Reuter; Irmgard Merfort; Christoph M Schempp
Botanicals in dermatology: an evidence-based review.
American journal of clinical dermatology 2010;11(4):247-67.
2009: M Fronza; B Heinzmann; M Hamburger; S Laufer; Irmgard Merfort
Determination of the wound healing effect of Calendula extracts using the scratch assay with 3T3 fibroblasts.
Journal of ethnopharmacology 2009;126(3):463-7.
2009: Rebekka Schlatter; Kathrin Schmich; Ima Avalos Vizcarra; Peter Scheurich; Thomas Sauter; Christoph Borner; Michael Ederer; Irmgard Merfort; Oliver Sawodny
ON/OFF and beyond--a boolean model of apoptosis.
PLoS computational biology 2009;5(12):e1000595.
2009: Andrea Jocher; Gabriele Nist; Johannes M Weiss; Dieter Wetzel; Irmgard Merfort; Thilo Jakob; Christoph M Schempp
Allergenic potential of Arnica-containing formulations in Arnica-allergic patients.
Contact dermatitis 2009;61(5):304-6.
2009: Dominik Altevogt; Andrea Hrenn; Claudia Kern; Lilia Clima; Willi Bannwarth; Irmgard Merfort
A new assay format for NF-kappaB based on a DNA triple helix and a fluorescence resonance energy transfer.
Organic & biomolecular chemistry 2009;7(19):3934-9.
2009: Mathias Misiek; Jessica Williams; Kathrin Schmich; Wolfgang Hüttel; Irmgard Merfort; Christine E Salomon; Courtney C Aldrich; Dirk Hoffmeister
Structure and cytotoxicity of arnamial and related fungal sesquiterpene aryl esters.
Journal of natural products 2009;72(10):1888-91.
2009: Christoph Jäger; Andrea Hrenn; Jörn Zwingmann; Andreas Suter; Irmgard Merfort
Phytomedicines prepared from Arnica flowers inhibit the transcription factors AP-1 and NF-kappaB and modulate the activity of MMP1 and MMP13 in human and bovine chondrocytes.
Planta medica 2009;75(12):1319-25.
2009: F Casetti; W Jung; U Wölfle; J Reuter; K Neumann; B Gilb; A Wähling; S Wagner; Irmgard Merfort; Christoph M Schempp
Topical application of solubilized Reseda luteola extract reduces ultraviolet B-induced inflammation in vivo.
Journal of photochemistry and photobiology. B, Biology 2009;96(3):260-5.
2009: Agnès Millet; Florian Stintzing; Irmgard Merfort
Validation of a GC-FID method for rapid quantification of nicotine in fermented extracts prepared from Nicotiana tabacum fresh leaves and studies of nicotine metabolites.
Journal of pharmaceutical and biomedical analysis 2009;49(5):1166-71.
2009: Torsten Lingott; Christian Schleberger; José María Gutiérrez; Irmgard Merfort
High-resolution crystal structure of the snake venom metalloproteinase BaP1 complexed with a peptidomimetic: insight into inhibitor binding.
Biochemistry 2009;48(26):6166-74.
2009: C Schmidt; M Fronza; M Goettert; F Geller; S Luik; E M M Flores; C F Bittencourt; G D Zanetti; B M Heinzmann; S Laufer; Irmgard Merfort
Biological studies on Brazilian plants used in wound healing.
Journal of ethnopharmacology 2009;122(3):523-32.
2008: Dorothée Walter; Kathrin Schmich; Sandra Vogel; Robert Pick; Thomas Kaufmann; Florian Christoph Hochmuth; Angelika Haber; Karin Neubert; Sabine McNelly; Fritz von Weizsäcker; Irmgard Merfort; Ulrich Maurer; Andreas Strasser; Christoph Borner
Switch from type II to I Fas/CD95 death signaling on in vitro culturing of primary hepatocytes.
Hepatology (Baltimore, Md.) 2008;48(6):1942-53.
2008: Steffen Wagner; Abraham Ureña; Eike Reich; Irmgard Merfort
Validated HPTLC methods for the determination of salicin in Salix sp. and of harpagoside in Harpagophytum [corrected] procumbens.
Journal of pharmaceutical and biomedical analysis 2008;48(3):587-91.
2008: Günter Seelinger; Irmgard Merfort; Christoph M Schempp
Anti-oxidant, anti-inflammatory and anti-allergic activities of luteolin.
Planta medica 2008;74(14):1667-77.
2008: Eun Myoung Shin; Hong Yu Zhou; Lian Yu Guo; Jeong Ah Kim; Seung Ho Lee; Irmgard Merfort; Sam Sik Kang; Hak-Sung Kim; Sanghee Kim; Yeong Shik Kim
Anti-inflammatory effects of glycyrol isolated from Glycyrrhiza uralensis in LPS-stimulated RAW264.7 macrophages.
International immunopharmacology 2008;8(11):1524-32.
2008: Christian Lass; Marc Vocanson; Steffen Wagner; Christoph M Schempp; Jean-Francois Nicolas; Irmgard Merfort; Stefan F Martin
Anti-inflammatory and immune-regulatory mechanisms prevent contact hypersensitivity to Arnica montana L.
Experimental dermatology 2008;17(10):849-57.
2008: Nilton S Arakawa; Karin Schorr; Sérgio R Ambrósio; Irmgard Merfort; Fernando B Da Costa
Further sesquiterpene lactones from Viguiera robusta and the potential anti-inflammatory activity of a heliangolide: inhibition of human neutrophil elastase release.
Zeitschrift für Naturforschung. C, Journal of biosciences 2008;63(7-8):533-8.
2008: Frank Götschel; Claudia Kern; Simona Lang; Titus Sparna; Cordula Markmann; Joseph Schwager; Sabine McNelly; Fritz von Weizsäcker; Stefan Laufer; Andreas Hecht; Irmgard Merfort
Inhibition of GSK3 differentially modulates NF-kappaB, CREB, AP-1 and beta-catenin signaling in hepatocytes, but fails to promote TNF-alpha-induced apoptosis.
Experimental cell research 2008;314(6):1351-66.
2008: Steffen Wagner; Raul Arce; Renato Murillo; Lothar Terfloth; Johann Gasteiger; Irmgard Merfort
Neural networks as valuable tools to differentiate between sesquiterpene lactones' inhibitory activity on serotonin release and on NF-kappaB.
Journal of medicinal chemistry 2008;51(5):1324-32.
2008: Jens Soltau; Ute Zirrgiebel; Norbert Esser; Christoph Schächtele; Frank Totzke; Clemens Unger; Irmgard Merfort; Joachim Drevs
Antitumoral and antiangiogenic efficacy of bisphosphonates in vitro and in a murine RENCA model.
Anticancer research 2008;28(2A):933-41.
2008: Thomas Steinbrecher; Andrea Hrenn; Korinna L Dormann; Irmgard Merfort; Andreas Labahn
Bornyl (3,4,5-trihydroxy)-cinnamate--an optimized human neutrophil elastase inhibitor designed by free energy calculations.
Bioorganic & medicinal chemistry 2008;16(5):2385-90.
2008: Günter Seelinger; Irmgard Merfort; Ute Wölfle; Christoph M Schempp
Anti-carcinogenic effects of the flavonoid luteolin.
Molecules (Basel, Switzerland) 2008;13(10):2628-51.
2007: Roman Huber; Amelie V Ditfurth; Frank Amann; Corina Güthlin; Matthias Rostock; Rainer Trittler; Klaus Kümmerer; Irmgard Merfort
Tormentil for active ulcerative colitis: an open-label, dose-escalating study.
Journal of clinical gastroenterology 2007;41(9):834-8.
2007: Bettina Siedle; Andrea Hrenn; Irmgard Merfort
Natural compounds as inhibitors of human neutrophil elastase.
Planta medica 2007;73(5):401-20.
2007: Maja T Lindenmeyer; C Kern; Titus Sparna; Johannes Donauer; Jochen Wilpert; Joseph Schwager; Debora Porath; Clemens Kreutz; Jens Timmer; Irmgard Merfort
Microarray analysis reveals influence of the sesquiterpene lactone parthenolide on gene transcription profiles in human epithelial cells.
Life sciences 2007;80(17):1608-18.
2007: Steffen Wagner; Irmgard Merfort
Skin penetration behaviour of sesquiterpene lactones from different Arnica preparations using a validated GC-MSD method.
Journal of pharmaceutical and biomedical analysis 2007;43(1):32-8.
2007: Nancy López-Antón; Corinna Hermann; Renato Murillo; Irmgard Merfort; Gerhard Wanner; Angelika M Vollmar; Verena M Dirsch
Sesquiterpene lactones induce distinct forms of cell death that modulate human monocyte-derived macrophage responses.
Apoptosis : an international journal on programmed cell death 2007;12(1):141-53.
2006: Andrea Hrenn; Thomas Steinbrecher; Andreas Labahn; Joseph Schwager; Christoph M Schempp; Irmgard Merfort
Plant phenolics inhibit neutrophil elastase.
Planta medica 2006;72(12):1127-31.
2006: Ricardo Stefani; Karin Schorr; Juliana Maria Tureta; Walter Vichnewski; Irmgard Merfort; Fernando B Da Costa
Sesquiterpene lactones from Dimerostemma species (Asteraceae) and in vitro potential anti-inflammatory activities.
Zeitschrift für Naturforschung. C, Journal of biosciences 2006;61(9-10):647-52.
2006: Irmgard Merfort
Patented inhibitors (2002 - 2005) of the transcription factor NF-kappaB.
Expert opinion on therapeutic patents 2006;16(6):797-810.
2006: Maja T Lindenmeyer; Andrea Hrenn; Claudia Kern; Victor Castro; Renato Murillo; Stefan Müller; Stefan Laufer; Jürgen Schulte-Mönting; Bettina Siedle; Irmgard Merfort
Sesquiterpene lactones as inhibitors of IL-8 expression in HeLa cells.
Bioorganic & medicinal chemistry 2006;14(8):2487-97.
2006: Steffen Wagner; Angelika Hofmann; Bettina Siedle; Lothar Terfloth; Irmgard Merfort; Johann Gasteiger
Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks.
Journal of medicinal chemistry 2006;49(7):2241-52.
2006: Stefan F Martin; Irmgard Merfort; Hermann-Josef Thierse
Interactions of chemicals and metal ions with proteins and role for immune responses.
Mini reviews in medicinal chemistry 2006;6(3):247-55.
2006: Renate Spitaler; P Daniel Schlorhaufer; Ernst P Ellmerer; Irmgard Merfort; Sigmar Bortenschlager; Hermann Stuppner; Christian Zidorn
Altitudinal variation of secondary metabolite profiles in flowering heads of Arnica montana cv. ARBO.
Phytochemistry 2006;67(4):409-17.
2006: Olha Kos; Victor Castro; Renato Murillo; Luis Poveda; Irmgard Merfort
Ent-kaurane glycosides and sesquiterpene lactones of the hirsutinolide type from Vernonia triflosculosa.
Phytochemistry 2006;67(1):62-9.
2005: Guntram A Grassl; Sabine Fessele; Irmgard Merfort; Maja T Lindenmeyer; Victor Castro; Renato Murillo; Peter J Nelson; Ingo B Autenrieth
Sesquiterpene lactones inhibit Yersinia invasin protein-induced IL-8 and MCP-1 production in epithelial cells.
International journal of medical microbiology : IJMM 2005;295(8):531-8.
2005: Olha Kos; Maja T Lindenmeyer; Aurelia Tubaro; Silvio Sosa; Irmgard Merfort
New sesquiterpene lactones from Arnica tincture prepared from fresh flowerheads of Arnica montana.
Planta medica 2005;71(11):1044-52.
2005: Karin Schorr; Anita Rott; Fernando B Da Costa; Irmgard Merfort
Optimisation of a human neutrophil elastase assay and investigation of the effect of sesquiterpene lactones.
Biologicals : journal of the International Association of Biological Standardization 2005;33(3):175-84.
2005: Vitelbina Núñez; Victor Castro; Renato Murillo; Luis Alberto Ponce-Soto; Irmgard Merfort; Bruno Lomonte
Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle.
Phytochemistry 2005;66(9):1017-25.
2005: Abebe Endale; Victor Wray; Renato Murillo; Peter C Schmidt; Irmgard Merfort
Hopane-type saponins from the seeds of Glinus lotoides.
Journal of natural products 2005;68(3):443-6.
2004: Bettina Siedle; Alfonso J García-Piñeres; Renato Murillo; Jürgen Schulte-Mönting; Victor Castro; Peter Rüngeler; Christoph A Klaas; Fernando B Da Costa; Wanda Kisiel; Irmgard Merfort
Quantitative structure-activity relationship of sesquiterpene lactones as inhibitors of the transcription factor NF-kappaB.
Journal of medicinal chemistry 2004;47(24):6042-54.
2004: Steffen Wagner; Andreas Suter; Irmgard Merfort
Skin penetration studies of Arnica preparations and of their sesquiterpene lactones.
Planta medica 2004;70(10):897-903.
2004: Alfonso J García-Piñeres; Maja T Lindenmeyer; Irmgard Merfort
Role of cysteine residues of p65/NF-kappaB on the inhibition by the sesquiterpene lactone parthenolide and N-ethyl maleimide, and on its transactivating potential.
Life sciences 2004;75(7):841-56.
2004: Maja T Lindenmeyer; Alfonso J García-Piñeres; Victor Castro; Irmgard Merfort
Sesquiterpene lactones inhibit luciferase but not beta-galactosidase activity in vitro and ex vivo.
Analytical biochemistry 2004;328(2):147-54.
2004: Stefan Müller; Renato Murillo; Victor Castro; Volker Brecht; Irmgard Merfort
Sesquiterpene lactones from Montanoa hibiscifolia that inhibit the transcription factor NF-kappa B.
Journal of natural products 2004;67(4):622-30.
2004: Steffen Wagner; Felix Kratz; Irmgard Merfort
In vitro behaviour of sesquiterpene lactones and sesquiterpene lactone-containing plant preparations in human blood, plasma and human serum albumin solutions.
Planta medica 2004;70(3):227-33.
2003: Silvana Petrovic; Silva Dobric; Dubravko R Bokonjic; Marjan Niketic; Alfonso J García-Piñeres; Irmgard Merfort
Evaluation of Tanacetum larvatum for an anti-inflammatory activity and for the protection against indomethacin-induced ulcerogenesis in rats.
Journal of ethnopharmacology 2003;87(1):109-13.
2003: Stefan Müller; Carlos R Tirapelli; Ana M De Oliveira; Renato Murillo; Victor Castro; Irmgard Merfort
Studies of ent-kaurane diterpenes from Oyedaea verbesinoides for their inhibitory activity on vascular smooth muscle contraction.
Phytochemistry 2003;63(4):391-6.
2003: Bettina Siedle; Renato Murillo; Oliver Hucke; Andreas Labahn; Irmgard Merfort
Structure activity relationship studies of cinnamic acid derivatives as inhibitors of human neutrophil elastase revealed by ligand docking calculations.
Die Pharmazie 2003;58(5):337-9.
2003: Matjaz Humar; Alfonso J García-Piñeres; Victor Castro; Irmgard Merfort
Effect of sesquiterpene lactones on the expression of the activation marker CD69 and of IL-2 in T-lymphocytes in whole blood.
Biochemical pharmacology 2003;65(9):1551-63.
2003: Bettina Siedle; Linda Gustavsson; Senia Johansson; Renato Murillo; Victor Castro; Lars Bohlin; Irmgard Merfort
The effect of sesquiterpene lactones on the release of human neutrophil elastase.
Biochemical pharmacology 2003;65(5):897-903.
2002: Bettina Siedle; S Cisielski; Renato Murillo; B Löser; Victor Castro; Christoph A Klaas; Oliver Hucke; Andreas Labahn; Matthias F Melzig; Irmgard Merfort
Sesquiterpene lactones as inhibitors of human neutrophil elastase.
Bioorganic & medicinal chemistry 2002;10(9):2855-61.
2002: Irmgard Merfort
Review of the analytical techniques for sesquiterpenes and sesquiterpene lactones.
Journal of chromatography. A 2002;967(1):115-30.
2002: Karin Schorr; Alfonso J García-Piñeres; Bettina Siedle; Irmgard Merfort; Fernando B Da Costa
Guaianolides from Viguiera gardneri inhibit the transcription factor NF-kappaB.
Phytochemistry 2002;60(7):733-40.
2002: José L Aguilar; Percy Rojas; Adolfo Marcelo; Alberto Plaza; Rudolf Bauer; Eveline Reininger; Christoph A Klaas; Irmgard Merfort
Anti-inflammatory activity of two different extracts of Uncaria tomentosa (Rubiaceae).
Journal of ethnopharmacology 2002;81(2):271-6.
2002: Christoph A Klaas; Gerd Wagner; Stefan Laufer; Silvio Sosa; Roberto Della Loggia; Ulrich Bomme; Heike L Pahl; Irmgard Merfort
Studies on the anti-inflammatory activity of phytopharmaceuticals prepared from Arnica flowers.
Planta medica 2002;68(5):385-91.
2001: Alfonso J García-Piñeres; Victor Castro; G Mora; Thomas Schmidt; Elisabeth Strunck; Heike L Pahl; Irmgard Merfort
Cysteine 38 in p65/NF-kappaB plays a crucial role in DNA binding inhibition by sesquiterpene lactones.
The Journal of biological chemistry 2001;276(43):39713-20.
2001: E Koch; Christoph A Klaas; Peter Rüngeler; Victor Castro; G Mora; Walter Vichnewski; Irmgard Merfort
Inhibition of inflammatory cytokine production and lymphocyte proliferation by structurally different sesquiterpene lactones correlates with their effect on activation of NF-kappaB.
Biochemical pharmacology 2001;62(6):795-801.
2001: B Zorn; Alfonso J García-Piñeres; Victor Castro; Renato Murillo; G Mora; Irmgard Merfort
3-Desoxyanthocyanidins from Arrabidaea chica.
Phytochemistry 2001;56(8):831-5.
2001: Peter Rüngeler; Volker Brecht; Giselle Tamayo; Irmgard Merfort
Germacranolides from Mikania guaco.
Phytochemistry 2001;56(5):475-89.
2000: Victor Castro; Renato Murillo; Christoph A Klaas; C Meunier; G Mora; Heike L Pahl; Irmgard Merfort
Inhibition of the transcription factor NF-kappa B by sesquiterpene lactones from Podachaenium eminens.
Planta medica 2000;66(7):591-5.
2000: Victor Castro; Peter Rüngeler; Renato Murillo; E Hernandez; G Mora; Heike L Pahl; Irmgard Merfort
Study of sesquiterpene lactones from Milleria quinqueflora on their anti-inflammatory activity using the transcription factor NF-kappa B as molecular target.
Phytochemistry 2000;53(2):257-63.
1999: Thomas Schmidt; G Lyss; Heike L Pahl; Irmgard Merfort
Helenanolide type sesquiterpene lactones. Part 5: the role of glutathione addition under physiological conditions.
Bioorganic & medicinal chemistry 1999;7(12):2849-55.
1999: Christian Zidorn; Verena M Dirsch; Peter Rüngeler; Silvio Sosa; Roberto Della Loggia; Irmgard Merfort; Heike L Pahl; A M Vollmar; Hermann Stuppner
Anti-inflammatory activities of hypocretenolides from Leontodon hispidus.
Planta medica 1999;65(8):704-8.
1999: Peter Rüngeler; Victor Castro; G Mora; N Gören; Walter Vichnewski; Heike L Pahl; Irmgard Merfort; Thomas Schmidt
Inhibition of transcription factor NF-kappaB by sesquiterpene lactones: a proposed molecular mechanism of action.
Bioorganic & medicinal chemistry 1999;7(11):2343-52.
1999: Matthias F Melzig; B Löser; G O Lobitz; Giselle Tamayo; Irmgard Merfort
Inhibition of granulocyte elastase activity by caffeic acid derivatives.
Die Pharmazie 1999;54(9):712.
1998: G Lyss; A Knorre; Thomas Schmidt; Heike L Pahl; Irmgard Merfort
The anti-inflammatory sesquiterpene lactone helenalin inhibits the transcription factor NF-kappaB by directly targeting p65.
The Journal of biological chemistry 1998;273(50):33508-16.
1998: Peter Rüngeler; G Lyss; Victor Castro; G Mora; Heike L Pahl; Irmgard Merfort
Study of three sesquiterpene lactones from Tithonia diversifolia on their anti-inflammatory activity using the transcription factor NF-kappa B and enzymes of the arachidonic acid pathway as targets.
Planta medica 1998;64(7):588-93.
1997: G Lyss; Thomas Schmidt; Irmgard Merfort; Heike L Pahl
Helenalin, an anti-inflammatory sesquiterpene lactone from Arnica, selectively inhibits transcription factor NF-kappaB.
Biological chemistry 1997;378(9):951-61.
1996: Irmgard Merfort; J Heilmann; M Weiss; Piergiorgio Pietta; Claudio Gardana
Radical scavenger activity of three flavonoid metabolites studied by inhibition of chemiluminescence in human PMNs.
Planta medica 1996;62(4):289-92.
1996: Claus M Passreiter; Irmgard Merfort; C Bestendonk; G Willuhn; A Steigel
11Alpha,13-and 11beta,13-dihydro-4H-xanthalongin 4-O-beta-glucopyranosides: new sesquiterpene lactone glycosides from flowers of Arnica amplexicaulis and A. mollis.
Planta medica 1996;62(1):39-41.
1995: Herman J Woerdenbag; Irmgard Merfort; Claus M Passreiter; Niesko Pras; T J Schmidt; W van Uden; Günter Willuhn; Antonius W T Konings
Decreased helenalin-induced cytotoxicity by flavonoids from Arnica as studied in a human lung carcinoma cell line.
Phytomedicine : international journal of phytotherapy and phytopharmacology 1995;2(2):127-32.
1995: J Heilmann; Irmgard Merfort; M Weiss
Radical scavenger activity of different 3',4'-dihydroxyflavonols and 1,5-dicaffeoylquinic acid studied by inhibition of chemiluminescence.
Planta medica 1995;61(5):435-8.
1994: Herman J Woerdenbag; Irmgard Merfort; Claus M Passreiter; Thomas Schmidt; G Willuhn; W van Uden; Niesko Pras; Harm H Kampinga; Antonius W T Konings
Cytotoxicity of flavonoids and sesquiterpene lactones from Arnica species against the GLC4 and the COLO 320 cell lines.
Planta medica 1994;60(5):434-7.
1994: Irmgard Merfort; J Heilmann; U Hagedorn-Leweke; Bernhard C Lippold
In vivo skin penetration studies of camomile flavones.
Die Pharmazie 1994;49(7):509-11.
1993: Irmgard Merfort; J Heilmann
[41st Anniversary of the Society for Medicinal Plant Research in Dusseldorf].
Pharmazie in unserer Zeit 1993;22(5-6):323-8.