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Matthias Merkenschlager

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Luis Aragon; Enrique Martinez-Perez; Matthias Merkenschlager
Condensin, cohesin and the control of chromatin states.
Francesco M Piccolo; Jorge Soza-Ried; Takashi Tada; Hakan Bagci; Karen E Brown; Meelad M Dawlaty; Amelie Feytout; Petra Hajkova; Rudolf Jaenisch; Skirmantas Kriaucionis; David Landeira; Harry G Leitch; Matthias Merkenschlager; Dylan Mooijman; Amanda G Fisher
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Matthias Merkenschlager; Duncan T Odom
CTCF and cohesin: linking gene regulatory elements with their targets.

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All Publications

2013: Luis Aragon; Enrique Martinez-Perez; Matthias Merkenschlager
Condensin, cohesin and the control of chromatin states.
Current opinion in genetics & development 2013;23(2):204-11.
2013: Francesco M Piccolo; Jorge Soza-Ried; Takashi Tada; Hakan Bagci; Karen E Brown; Meelad M Dawlaty; Amelie Feytout; Petra Hajkova; Rudolf Jaenisch; Skirmantas Kriaucionis; David Landeira; Harry G Leitch; Matthias Merkenschlager; Dylan Mooijman; Amanda G Fisher
Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.
Molecular cell 2013;49(6):1023-33.
2013: Matthias Merkenschlager; Duncan T Odom
CTCF and cohesin: linking gene regulatory elements with their targets.
Cell 2013;152(6):1285-97.
2013: Isabel Ferreirós-Vidal; Amanda G Fisher; Sanjay Khadayate; Ziwei Liang; Ludovica Bruno; Thomas Carroll; Bradley S Cobb; Gopuraja Dharmalingam; Enrico Petretto; Stephen T Smale; Mikhail Spivakov; Prashant Srivastava; Benjamin Taylor; Anna Terry; Matthias Merkenschlager
Genome-wide identification of Ikaros targets elucidates its contribution to mouse B-cell lineage specification and pre-B-cell differentiation.
Blood 2013;121(10):1769-82.
2013: Tomomi Tsubouchi; Hakan Bagci; Karen Brown; Irene Cantone; Helfrid Hochegger; David Landeira; Matthias Merkenschlager; Francesco M Piccolo; Jorge Soza-Ried; Amanda G Fisher
DNA synthesis is required for reprogramming mediated by stem cell fusion.
Cell 2013;152(4):873-83.
2012: Changgeng Peng; Fabian J Theis; Wolfgang Wurst; Jingzhong Zhang; Wei Chen; Na Li; Florian Meier; Matthias Merkenschlager; Yen-Kar Ng; Nilima Prakash
A unilateral negative feedback loop between miR-200 microRNAs and Sox2/E2F3 controls neural progenitor cell-cycle exit and differentiation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(38):13292-308.
2012: Vlad C Seitan; Michael S Krangel; Matthias Merkenschlager
Cohesin, CTCF and lymphocyte antigen receptor locus rearrangement.
Trends in immunology 2012;33(4):153-9.
2012: Vlad C Seitan; Matthias Merkenschlager
Cohesin and chromatin organisation.
Current opinion in genetics & development 2012;22(2):93-100.
2011: Andres Clemente-Blanco; Dirk Eick; Laurence Game; Adam Giess; Bryony Graham; Adam Jarmuz; Maria Mayan-Santos; Matthias Merkenschlager; Maria P Sacristán; Nicholas Sen; Elizabeth Webb; Avelino Bueno; Luis Aragón
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription.
Nature cell biology 2011;13(12):1450-6.
2011: Vlad C Seitan; Kikuë Tachibana-Konwalski; Grace Teng; Anna Terry; Hegias Mira-Bontenbal; Kim Nasmyth; David G Schatz; David J Adams; Luis Aragon; Karen E Brown; Tom Carroll; Amanda G Fisher; bingtao hao; Katie Horan; Michael S Krangel; Thais Lavagnolli; Hendrik Marks; Matthias Merkenschlager
A role for cohesin in T-cell-receptor rearrangement and thymocyte differentiation.
Nature 2011;476(7361):467-71.
2011: Francesco M Piccolo; Jorge Soza-Ried; Tomomi Tsubouchi; Karen Brown; Irene Cantone; Matthias Merkenschlager; Carlos Filipe Pereira; Amanda G Fisher
Using heterokaryons to understand pluripotency and reprogramming.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2011;366(1575):2260-5.
2011: Luca Mazzarella; Helle F Jørgensen; Jorge Soza-Ried; Anna V Terry; Stella Pearson; Georges Lacaud; Valerie Kouskoff; Matthias Merkenschlager; Amanda G Fisher
Embryonic stem cell-derived hemangioblasts remain epigenetically plastic and require PRC1 to prevent neural gene expression.
Blood 2011;117(1):83-7.
2010: Matthias Merkenschlager
Ikaros in immune receptor signaling, lymphocyte differentiation, and function.
FEBS letters 2010;584(24):4910-4.
2010: Witold Konopka; Anna Kiryk; Martin Novak; Marina Herwerth; Jan Rodriguez Parkitna; Marcin Wawrzyniak; Andreas Kowarsch; Piotr Michaluk; Joanna Dzwonek; Tabea Arnsperger; Grzegorz Wilczynski; Matthias Merkenschlager; Fabian J Theis; Georg Köhr; Leszek Kaczmarek; Günther Schütz
MicroRNA loss enhances learning and memory in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(44):14835-42.
2010: Matthias Merkenschlager
Cohesin: a global player in chromosome biology with local ties to gene regulation.
Current opinion in genetics & development 2010;20(5):555-61.
2010: Thomas Spruce; Barbara Pernaute; Aida Di-Gregorio; Bradley S Cobb; Matthias Merkenschlager; Miguel Manzanares; Tristan A Rodriguez
An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.
Developmental cell 2010;19(2):207-19.
2010: Jing Zhao; Man-Cheung Lee; Ali Momin; Cruz-Miguel Cendan; Samuel T Shepherd; Mark D Baker; Curtis Asante; Lucy Bee; Audrey Bethry; James R Perkins; Mohammed A Nassar; Bjarke Abrahamsen; Anthony Dickenson; Bradly S Cobb; Matthias Merkenschlager; John N Wood
Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(32):10860-71.
2010: Shangqin Guo; Jun Lu; Rita Schlanger; Hao Zhang; Judy Y Wang; Michelle Candice Fox; Louise E Purton; Heather H Fleming; Bradley Cobb; Matthias Merkenschlager; Todd R Golub; David T Scadden
MicroRNA miR-125a controls hematopoietic stem cell number.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(32):14229-34.
2010: Matthias Merkenschlager; Harald von Boehmer
PI3 kinase signalling blocks Foxp3 expression by sequestering Foxo factors.
The Journal of experimental medicine 2010;207(7):1347-50.
2010: Amanda G Fisher; Matthias Merkenschlager
Fresh powder on Waddington's slopes.
EMBO reports 2010;11(7):490-2.
2010: Carlos Filipe Pereira; Francesco M Piccolo; Tomomi Tsubouchi; Stephan Sauer; Natalie K Ryan; Ludovica Bruno; David Landeira; Joana Santos; Ana Banito; Jesus Gil; Haruhiko Koseki; Matthias Merkenschlager; Amanda G Fisher
ESCs require PRC2 to direct the successful reprogramming of differentiated cells toward pluripotency.
Cell stem cell 2010;6(6):547-56.
2010: David Landeira; Stephan Sauer; Raymond A Poot; Maria Dvorkina; Luca Mazzarella; Helle F Jørgensen; Carlos Filipe Pereira; Marion Leleu; Francesco M Piccolo; Mikhail Spivakov; Emily Brookes; Ana Pombo; Cynthia Fisher; William C Skarnes; Tim Snoek; Karel Bezstarosti; Jeroen Demmers; Robert J Klose; Miguel Casanova; Ligia Tavares; Neil Brockdorff; Matthias Merkenschlager; Amanda G Fisher
Jarid2 is a PRC2 component in embryonic stem cells required for multi-lineage differentiation and recruitment of PRC1 and RNA Polymerase II to developmental regulators.
Nature cell biology 2010;12(6):618-24.
2010: Marc H G P Raaijmakers; Siddhartha Mukherjee; Shangqin Guo; Siyi Zhang; Tatsuya Kobayashi; Jesse A Schoonmaker; Benjamin L Ebert; Fatima Al-Shahrour; Robert P Hasserjian; Edward O Scadden; Zinmar Aung; Marc Matza; Matthias Merkenschlager; Charles Lin; Johanna M Rommens; David T Scadden
Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia.
Nature 2010;464(7290):852-7.
2010: Joana Santos; Carlos Filipe Pereira; Aida Di-Gregorio; Thomas Spruce; Olivia Alder; Tristan Rodriguez; Véronique Azuara; Matthias Merkenschlager; Amanda G Fisher
Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo.
Epigenetics & chromatin 2010;3():1.
2010: Gwang-Jin Kim; Ina Georg; Harry Scherthan; Matthias Merkenschlager; Florian Guillou; Gerd Scherer; Francisco Barrionuevo
Dicer is required for Sertoli cell function and survival.
The International journal of developmental biology 2010;54(5):867-75.
2009: Ludovica Bruno; Luca Mazzarella; Maarten Hoogenkamp; Arnulf Hertweck; Bradley S Cobb; Stephan Sauer; Suzana Hadjur; Marion Leleu; Yoshinori Naoe; Janice C Telfer; Constanze Bonifer; Ichiro Taniuchi; Amanda G Fisher; Matthias Merkenschlager
Runx proteins regulate Foxp3 expression.
The Journal of experimental medicine 2009;206(11):2329-37.
2009: Maya Fedeli; Anna Napolitano; Molly Pui Man Wong; Antoine Marcais; Claudia De Lalla; Francesco Colucci; Matthias Merkenschlager; Paolo Dellabona; Giulia Casorati
Dicer-dependent microRNA pathway controls invariant NKT cell development.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2506-12.
2009: Suzana Hadjur; Luke M Williams; Natalie K Ryan; Bradley S Cobb; Tom Sexton; P Fraser; Amanda G Fisher; Matthias Merkenschlager
Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus.
Nature 2009;460(7253):410-3.
2009: Marie-Laure Caparros; Amanda G Fisher; Matthias Merkenschlager
Chromosomes and expression mechanisms: life on the edge.
Current opinion in genetics & development 2009;19(2):97-8.
2009: Sarion R Bowers; Fabio Mirabella; Fernando J Calero-Nieto; Stephanie Valeaux; Suzana Hadjur; Euan W Baxter; Matthias Merkenschlager; Peter N Cockerill
A conserved insulator that recruits CTCF and cohesin exists between the closely related but divergently regulated interleukin-3 and granulocyte-macrophage colony-stimulating factor genes.
Molecular and cellular biology 2009;29(7):1682-93.
2009: Helle F Jørgensen; Anna Terry; Chiara Beretta; Carlos Filipe Pereira; Marion Leleu; Zhou-Feng Chen; Claire Kelly; Matthias Merkenschlager; Amanda G Fisher
REST selectively represses a subset of RE1-containing neuronal genes in mouse embryonic stem cells.
Development (Cambridge, England) 2009;136(5):715-21.
2009: Helle F Jørgensen; Zhou-Feng Chen; Matthias Merkenschlager; Amanda G Fisher
Is REST required for ESC pluripotency?
Nature 2009;457(7233):E4-5; discussion E7.
2009: Suzana Hadjur; Ludovica Bruno; Arnulf Hertweck; Bradley S Cobb; Benjamin Taylor; Amanda G Fisher; Matthias Merkenschlager
IL4 blockade of inducible regulatory T cell differentiation: the role of Th2 cells, Gata3 and PU.1.
Immunology letters 2009;122(1):37-43.
2009: Benjamin Taylor; Bradley S Cobb; Ludovica Bruno; Zoe Webster; Amanda G Fisher; Matthias Merkenschlager
A reappraisal of evidence for probabilistic models of allelic exclusion.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):516-21.
2008: Shaolin Shi; Liping Yu; Celine Chiu; Yezhou Sun; Jin Chen; Greg Khitrov; Matthias Merkenschlager; Lawrence B Holzman; Weijia Zhang; Peter Mundel; Erwin P Bottinger
Podocyte-selective deletion of dicer induces proteinuria and glomerulosclerosis.
Journal of the American Society of Nephrology : JASN 2008;19(11):2159-69.
2008: Yajaira Suárez; Carlos Fernández-Hernando; Jun Yu; Scott A Gerber; Kenneth D Harrison; Jordan S Pober; M Luisa Iruela-Arispe; Matthias Merkenschlager; William C Sessa
Dicer-dependent endothelial microRNAs are necessary for postnatal angiogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14082-7.
2008: Ludovica Bruno; Matthias Merkenschlager
Directing T cell differentiation and function with small molecule inhibitors.
Cell cycle (Georgetown, Tex.) 2008;7(15):2296-8.
2008: Stephan Sauer; Ludovica Bruno; Arnulf Hertweck; David Finlay; Marion Leleu; Mikhail Spivakov; Zachary A Knight; Bradley S Cobb; Doreen Cantrell; Eric O'connor; Kevan M Shokat; Amanda G Fisher; Matthias Merkenschlager
T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(22):7797-802.
2008: Emily Rowell; Matthias Merkenschlager; Christopher B Wilson
Long-range regulation of cytokine gene expression.
Current opinion in immunology 2008;20(3):272-80.
2008: Matthias Merkenschlager; Christopher B Wilson
RNAi and chromatin in T cell development and function.
Current opinion in immunology 2008;20(2):131-8.
2008: Sergei B Koralov; Stefan A Muljo; Gunther R Galler; Azra Krek; Tirtha Chakraborty; Chrysi Kanellopoulou; Kari Jensen; Bradley S Cobb; Matthias Merkenschlager; Nikolaus Rajewsky; Klaus Rajewsky
Dicer ablation affects antibody diversity and cell survival in the B lymphocyte lineage.
Cell 2008;132(5):860-74.
2008: Tatsuya Kobayashi; Jun Lu; Bradley S Cobb; Stephen J Rodda; Andrew P McMahon; Ernestina Schipani; Matthias Merkenschlager; Henry M Kronenberg
Dicer-dependent pathways regulate chondrocyte proliferation and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):1949-54.
2008: Vania Parelho; Suzana Hadjur; Mikhail Spivakov; Marion Leleu; Stephan Sauer; Heather Gregson; Adam Jarmuz; Claudia Canzonetta; Zoe Webster; Tatyana B Nesterova; Bradley S Cobb; Kyoko Yokomori; Niall Dillon; Luis Aragon; Amanda G Fisher; Matthias Merkenschlager
Cohesins functionally associate with CTCF on mammalian chromosome arms.
Cell 2008;132(3):422-33.
2008: Tatyana B Nesterova; Bilyana C Popova; Bradley S Cobb; Sara Norton; Claire E Senner; Y Amy Tang; Thomas Spruce; Tristan A Rodriguez; Takashi Sado; Matthias Merkenschlager; Neil Brockdorff
Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a.
Epigenetics & chromatin 2008;1(1):2.
2008: Marc R Gartenberg; Matthias Merkenschlager
Condensin goes with the family but not with the flow.
Genome biology 2008;9(10):236.
2008: Carlos Filipe Pereira; Rémi Terranova; Natalie K Ryan; Joana Santos; Kelly J Morris; Wei Cui; Matthias Merkenschlager; Amanda G Fisher
Heterokaryon-based reprogramming of human B lymphocytes for pluripotency requires Oct4 but not Sox2.
PLoS genetics 2008;4(9):e1000170.
2007: Elizabeth C Thompson; Bradley S Cobb; Pierangela Sabbattini; Sonja Meixlsperger; Vania Parelho; David Liberg; Benjamin Taylor; Niall Dillon; Katia Georgopoulos; Hassan Jumaa; Stephen T Smale; Amanda G Fisher; Matthias Merkenschlager
Ikaros DNA-binding proteins as integral components of B cell developmental-stage-specific regulatory circuits.
Immunity 2007;26(3):335-44.
2007: Helle F Jørgensen; Véronique Azuara; Shannon Amoils; Mikhail Spivakov; Anna Terry; Tatyana B Nesterova; Bradley S Cobb; Bernard Ramsahoye; Matthias Merkenschlager; Amanda G Fisher
The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells.
Genome biology 2007;8(8):R169.
2006: Bradley S Cobb; Arnulf Hertweck; James Smith; Eric O'connor; Daniel Graf; Terence Cook; Stephen T Smale; Shimon Sakaguchi; Frederick J Livesey; Amanda G Fisher; Matthias Merkenschlager
A role for Dicer in immune regulation.
The Journal of experimental medicine 2006;203(11):2519-27.
2006: Rémi Terranova; Carlos Filipe Pereira; Camille Du Roure; Matthias Merkenschlager; Amanda G Fisher
Acquisition and extinction of gene expression programs are separable events in heterokaryon reprogramming.
Journal of cell science 2006;119(Pt 10):2065-72.
2006: Véronique Azuara; Pascale Perry; Stephan Sauer; Mikhail Spivakov; Helle F Jørgensen; Rosalind M John; Mina Gouti; Miguel Casanova; Gary Warnes; Matthias Merkenschlager; Amanda G Fisher
Chromatin signatures of pluripotent cell lines.
Nature cell biology 2006;8(5):532-8.
2006: Christopher B Wilson; Matthias Merkenschlager
Chromatin structure and gene regulation in T cell development and function.
Current opinion in immunology 2006;18(2):143-51.
2006: Camille Du Roure; Katalin Takács; Patrick H Maxwell; Irene Roberts; Francesco Dazzi; Laura Cannella; Matthias Merkenschlager; Amanda G Fisher
Correction of severe anaemia using immuno-regulated gene therapy is achieved by restoring the early erythroblast compartment.
British journal of haematology 2006;132(5):608-14.
2006: Ruth R E Williams; Véronique Azuara; Pascale Perry; Stephan Sauer; Maria Dvorkina; Helle Jørgensen; Jeffery Roix; Philip McQueen; Tom Misteli; Matthias Merkenschlager; Amanda G Fisher
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.
Journal of cell science 2006;119(Pt 1):132-40.
2005: Rémi Terranova; Stephan Sauer; Matthias Merkenschlager; Amanda G Fisher
The reorganisation of constitutive heterochromatin in differentiating muscle requires HDAC activity.
Experimental cell research 2005;310(2):344-56.
2005: Vania Parelho; Matthias Merkenschlager
Gene expression: growing up together may help genes go their separate ways.
European journal of human genetics : EJHG 2005;13(9):993-4.
2005: Bradley S Cobb; Tatyana B Nesterova; Elizabeth Thompson; Arnulf Hertweck; Eric O'connor; Jonathan Godwin; Christopher B Wilson; Neil Brockdorff; Amanda G Fisher; Stephen T Smale; Matthias Merkenschlager
T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer.
The Journal of experimental medicine 2005;201(9):1367-73.
2004: Matthias Merkenschlager; Shannon Amoils; Esther Roldan; Amin Rahemtulla; Eric O'connor; Amanda G Fisher; Karen E Brown
Centromeric repositioning of coreceptor loci predicts their stable silencing and the CD4/CD8 lineage choice.
The Journal of experimental medicine 2004;200(11):1437-44.
2004: Pascale Perry; Stephan Sauer; Nathalie Billon; William D Richardson; Mikhail Spivakov; Gary Warnes; Frederick J Livesey; Matthias Merkenschlager; Amanda G Fisher; Véronique Azuara
A dynamic switch in the replication timing of key regulator genes in embryonic stem cells upon neural induction.
Cell cycle (Georgetown, Tex.) 2004;3(12):1645-50.
2004: Susannah L Hewitt; Frances A High; Steven L Reiner; Amanda G Fisher; Matthias Merkenschlager
Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation.
European journal of immunology 2004;34(12):3604-13.
2004: Katalin Takács; Camille Du Roure; Stephen Nabarro; Niall Dillon; John H McVey; Zoe Webster; Angus Macneil; István Bartók; Christopher Higgins; David Gray; Matthias Merkenschlager; Amanda G Fisher
The regulated long-term delivery of therapeutic proteins by using antigen-specific B lymphocytes.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(46):16298-303.
2004: Jonathan Baxter; Stephan Sauer; Antoine Peters; Rosalind John; Ruth Williams; Marie-Laure Caparros; Katharine L Arney; Arie Otte; Thomas Jenuwein; Matthias Merkenschlager; Amanda G Fisher
Histone hypomethylation is an indicator of epigenetic plasticity in quiescent lymphocytes.
The EMBO journal 2004;23(22):4462-72.
2004: Ruey-Chyi Su; Karen E Brown; Sanam Saaber; Amanda G Fisher; Matthias Merkenschlager; Stephen T Smale
Dynamic assembly of silent chromatin during thymocyte maturation.
Nature genetics 2004;36(5):502-6.
2003: David Liberg; Stephen T Smale; Matthias Merkenschlager
Upstream of Ikaros.
Trends in immunology 2003;24(11):567-70.
2003: Véronique Azuara; Karen E Brown; Ruth R E Williams; Natasha Webb; Niall Dillon; Richard Festenstein; Veronica Buckle; Matthias Merkenschlager; Amanda G Fisher
Heritable gene silencing in lymphocytes delays chromatid resolution without affecting the timing of DNA replication.
Nature cell biology 2003;5(7):668-74.
2002: Tian-Hui Yang; Matthew Lovatt; Matthias Merkenschlager; Hans J Stauss
Comparison of the frequency of peptide-specific cytotoxic T lymphocytes restricted by self- and allo-MHC following in vitro T cell priming.
International immunology 2002;14(11):1283-90.
2002: Daniel Graf; Suran Nethisinghe; Donald B Palmer; Amanda G Fisher; Matthias Merkenschlager
The developmentally regulated expression of Twisted gastrulation reveals a role for bone morphogenetic proteins in the control of T cell development.
The Journal of experimental medicine 2002;196(2):163-71.
2002: Jonathan Baxter; Matthias Merkenschlager; Amanda G Fisher
Nuclear organisation and gene expression.
Current opinion in cell biology 2002;14(3):372-6.
2002: Amanda G Fisher; Matthias Merkenschlager
Gene silencing, cell fate and nuclear organisation.
Current opinion in genetics & development 2002;12(2):193-7.
2001: K Smith; Benedict Seddon; M A Purbhoo; Rose Zamoyska; Amanda G Fisher; Matthias Merkenschlager
Sensory adaptation in naive peripheral CD4 T cells.
The Journal of experimental medicine 2001;194(9):1253-61.
2001: François Davodeau; Michael J Difilippantonio; E Roldan; M Malissen; J L Casanova; Chrystelle Couedel; JF Morcet; Matthias Merkenschlager; A Nussenzweig; Marc Bonneville; B Malissen
The tight interallelic positional coincidence that distinguishes T-cell receptor Jalpha usage does not result from homologous chromosomal pairing during ValphaJalpha rearrangement.
The EMBO journal 2001;20(17):4717-29.
2001: J A Skok; Karen E Brown; Véronique Azuara; M L Caparros; Jonathan Baxter; K Takacs; Niall Dillon; D Gray; R P Perry; Matthias Merkenschlager; Amanda G Fisher
Nonequivalent nuclear location of immunoglobulin alleles in B lymphocytes.
Nature immunology 2001;2(9):848-54.
2001: L A Trinh; Roger Ferrini; Bradley S Cobb; Amy S Weinmann; K Hahm; Patricia Ernst; Isla P Garraway; Matthias Merkenschlager; Stephen T Smale
Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator.
Genes & development 2001;15(14):1817-32.
2001: Daniel Graf; P M Timmons; M Hitchins; Vasso Episkopou; G Moore; T Ito; A Fujiyama; Amanda G Fisher; Matthias Merkenschlager
Evolutionary conservation, developmental expression, and genomic mapping of mammalian Twisted gastrulation.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(7):554-60.
2001: Karen E Brown; S Amoils; J M Horn; Veronica Buckle; Douglas R Higgs; Matthias Merkenschlager; Amanda G Fisher
Expression of alpha- and beta-globin genes occurs within different nuclear domains in haemopoietic cells.
Nature cell biology 2001;3(6):602-6.
2000: Gabriela Barcenas-Morales; Matthias Merkenschlager; FN Wahid; Rainer Döffinger; Juraj Ivanyi
Recessive expression of the H2A-controlled immune response phenotype depends critically on antigen dose.
Immunology 2000;99(2):221-8.
2000: Matthew Lovatt; T H Yang; Hans J Stauss; Amanda G Fisher; Matthias Merkenschlager
Different doses of agonistic ligand drive the maturation of functional CD4 and CD8 T cells from immature precursors.
European journal of immunology 2000;30(2):371-81.
1999: Matthias Merkenschlager; M O Power; H Pircher; Amanda G Fisher
Intrathymic deletion of MHC class I-restricted cytotoxic T cell precursors by constitutive cross-presentation of exogenous antigen.
European journal of immunology 1999;29(5):1477-86.
1999: Karen E Brown; Jonathan Baxter; Daniel Graf; Matthias Merkenschlager; Amanda G Fisher
Dynamic repositioning of genes in the nucleus of lymphocytes preparing for cell division.
Molecular cell 1999;3(2):207-17.
1999: Patricia Ernst; K Hahm; Bradley S Cobb; Karen E Brown; L A Trinh; Aaron S McCarty; Matthias Merkenschlager; CA Klug; Amanda G Fisher; Stephen T Smale
Mechanisms of transcriptional regulation in lymphocyte progenitors: insight from an analysis of the terminal transferase promoter.
Cold Spring Harbor symposia on quantitative biology 1999;64():87-97.
1997: Karen E Brown; S S Guest; Stephen T Smale; K Hahm; Matthias Merkenschlager; Amanda G Fisher
Association of transcriptionally silent genes with Ikaros complexes at centromeric heterochromatin.
Cell 1997;91(6):845-54.
1997: Matthias Merkenschlager; Daniel Graf; Matthew Lovatt; Ursula Bommhardt; Rose Zamoyska; Amanda G Fisher
How many thymocytes audition for selection?
The Journal of experimental medicine 1997;186(7):1149-58.
1997: Daniel Graf; Amanda G Fisher; Matthias Merkenschlager
Rational primer design greatly improves differential display-PCR (DD-PCR).
Nucleic acids research 1997;25(11):2239-40.
1995: Amanda G Fisher; C Burdet; C Bunce; Matthias Merkenschlager; Rhodri Ceredig
Lymphoproliferative disorders in IL-7 transgenic mice: expansion of immature B cells which retain macrophage potential.
International immunology 1995;7(3):415-23.