FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Philip Merta

Research Profile

Chemicals & Drugs

Concepts & Ideas

Occupations

Drug Design

Anatomy

Procedures

Living Beings

Physiology

Phenomena

Protein Binding

Co-author Network

Publications

TOP 3
James T Metz; Eric F Johnson; Niru B Soni; Philip J Merta; Lemma Kifle; Philip J Hajduk
Navigating the kinome.
Steven L Swann; Scott P Brown; Steven W Muchmore; Hetal Patel; Philip J Merta; John Locklear; Philip J Hajduk
A unified, probabilistic framework for structure- and ligand-based virtual screening.
Steven L Swann; Philip J Merta; Lemma Kifle; Duncan Groebe; Kathy A Sarris; Philip J Hajduk; Chaohong Sun
Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Philip Merta (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2011: James T Metz; Eric F Johnson; Niru B Soni; Philip J Merta; Lemma Kifle; Philip J Hajduk
Navigating the kinome.
Nature chemical biology 2011;7(4):200-2.
2011: Steven L Swann; Scott P Brown; Steven W Muchmore; Hetal Patel; Philip J Merta; John Locklear; Philip J Hajduk
A unified, probabilistic framework for structure- and ligand-based virtual screening.
Journal of medicinal chemistry 2011;54(5):1223-32.
2010: Steven L Swann; Philip J Merta; Lemma Kifle; Duncan Groebe; Kathy A Sarris; Philip J Hajduk; Chaohong Sun
Biochemical and biophysical characterization of unique switch pocket inhibitors of p38α.
Bioorganic & medicinal chemistry letters 2010;20(19):5787-92.
2008: Lisa Hasvold; Le Wang; Magdalena Przytulinska; Zhan Xiao; Zehan Chen; Wen-Zhen Gu; Philip J Merta; John Xue; Peter Kovar; Haiying Zhang; Chang Park; Thomas J Sowin; Saul H Rosenberg; Nan-Horng Lin
Investigation of novel 7,8-disubstituted-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-ones as potent Chk1 inhibitors.
Bioorganic & medicinal chemistry letters 2008;18(7):2311-5.
2007: Gaoquan Li; Zhi-Fu Tao; Yunsong Tong; Magdalena Przytulinska; Peter Kovar; Philip J Merta; Zehan Chen; Haiying Zhang; Thomas J Sowin; Saul H Rosenberg; Nan-Horng Lin
Synthesis and in-vitro biological activity of macrocyclic urea Chk1 inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(23):6499-504.
2007: Zhi-Fu Tao; Gaoquan Li; Yunsong Tong; Kent D Stewart; Zehan Chen; Mai-Ha Bui; Philip J Merta; Chang Park; Peter Kovar; Haiying Zhang; Hing L Sham; Saul H Rosenberg; Thomas J Sowin; Nan-Horng Lin
Discovery of 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-benzonitriles and 4'-(1,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-pyridine-2'-carbonitriles as potent checkpoint kinase 1 (Chk1) inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(21):5944-51.
2007: Yunsong Tong; Magdalena Przytulinska; Zhi-Fu Tao; Jennifer J Bouska; Kent D Stewart; Chang Park; Gaoquan Li; Akiyo Claiborne; Peter Kovar; Zehan Chen; Philip J Merta; Mai-Ha Bui; Amanda Olson; Donald J Osterling; Haiying Zhang; Hing L Sham; Saul H Rosenberg; Thomas J Sowin; Nan-Horng Lin
Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: improving oral biovailability.
Bioorganic & medicinal chemistry letters 2007;17(20):5665-70.
2007: Le Wang; Gerard M Sullivan; Laura A Hexamer; Lisa Hasvold; Reema Thalji; Magdalena Przytulinska; Zhi-Fu Tao; Gaoquan Li; Zehan Chen; Zhan Xiao; Wen-Zhen Gu; John Xue; Mai-Ha Bui; Philip J Merta; Peter Kovar; Jennifer J Bouska; Haiying Zhang; Chang Park; Kent D Stewart; Hing L Sham; Thomas J Sowin; Saul H Rosenberg; Nan-Horng Lin
Design, synthesis, and biological activity of 5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one-based potent and selective Chk-1 inhibitors.
Journal of medicinal chemistry 2007;50(17):4162-76.
2007: Zhi-Fu Tao; Gaoquan Li; Yunsong Tong; Zehan Chen; Philip J Merta; Peter Kovar; Haiying Zhang; Saul H Rosenberg; Hing L Sham; Thomas J Sowin; Nan-Horng Lin
Synthesis and biological evaluation of 4'-(6,7-disubstituted-2,4-dihydro-indeno[1,2-c]pyrazol-3-yl)-biphenyl-4-ol as potent Chk1 inhibitors.
Bioorganic & medicinal chemistry letters 2007;17(15):4308-15.
2007: Yunsong Tong; Akiyo Claiborne; Magdalena Pyzytulinska; Zhi-Fu Tao; Kent D Stewart; Peter Kovar; Zehan Chen; Robert B Credo; Ran Guan; Philip J Merta; Haiying Zhang; Jennifer J Bouska; Elizabeth A Everitt; Bernard P Murry; Dean Hickman; Tim J Stratton; Jian Wu; Saul H Rosenberg; Hing L Sham; Thomas J Sowin; Nan-Horng Lin
1,4-Dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: extended exploration on phenyl ring substitutions and preliminary ADME/PK studies.
Bioorganic & medicinal chemistry letters 2007;17(13):3618-23.
2007: Zhi-Fu Tao; Le Wang; Kent D Stewart; Zehan Chen; Wendy Gu; Mai-Ha Bui; Philip J Merta; Haiying Zhang; Peter Kovar; Eric Johnson; Chang Park; Russell A Judge; Saul Rosenberg; Thomas J Sowin; Nan-Horng Lin
Structure-based design, synthesis, and biological evaluation of potent and selective macrocyclic checkpoint kinase 1 inhibitors.
Journal of medicinal chemistry 2007;50(7):1514-27.
2006: Mira M Hinman; Teresa A Rosenberg; Darlene Balli; Candace Black-Schaefer; Linda E Chovan; Douglas Kalvin; Philip J Merta; Angela M Nilius; Steve D Pratt; Niru B Soni; Frank L Wagenaar; Moshe Weitzberg; Rolf Wagner; Bruce A Beutel
Novel antibacterial class: a series of tetracyclic derivatives.
Journal of medicinal chemistry 2006;49(16):4842-56.
2005: Claude G Lerner; Stephan J Kakavas; Christian Wagner; Richard T Chang; Philip J Merta; Xiaoan Ruan; Randy E Metzger; Bruce A Beutel
Novel approach to mapping of resistance mutations in whole genomes by using restriction enzyme modulation of transformation efficiency.
Antimicrobial agents and chemotherapy 2005;49(7):2767-77.
2005: Zehan Chen; Philip J Merta; Nan-Horng Lin; Stephen K Tahir; Peter Kovar; Hing L Sham; Haiying Zhang
A-432411, a novel indolinone compound that disrupts spindle pole formation and inhibits human cancer cell growth.
Molecular cancer therapeutics 2005;4(4):562-8.
2004: Zhensheng Cao; Ping Zhong; Xiaoan Ruan; Philip J Merta; John O Capobianco; Robert K Flamm; Angela M Nilius
Ribosome affinity and the prolonged molecular postantibiotic effect of cethromycin (ABT-773) in Haemophilus influenzae.
International journal of antimicrobial agents 2004;24(4):362-8.
2004: Steve D Pratt; Caroline A David; Candace Black-Schaefer; Peter Dandliker; Xiaoling Xuei; Usha Warrior; David J Burns; Ping Zhong; Zhensheng Cao; Anne Y C Saiki; Claude G Lerner; Linda E Chovan; Niru B Soni; Angela M Nilius; Frank L Wagenaar; Philip J Merta; Linda M Traphagen; Bruce A Beutel
A strategy for discovery of novel broad-spectrum antibacterials using a high-throughput Streptococcus pneumoniae transcription/translation screen.
Journal of biomolecular screening 2004;9(1):3-11.
2003: Peter Dandliker; Steve D Pratt; Angela M Nilius; Candace Black-Schaefer; Xiaoan Ruan; Danli L Towne; Richard F Clark; Erika E Englund; Rolf Wagner; Moshe Weitzberg; Linda E Chovan; Robert Hickman; Melissa M Daly; Stephan J Kakavas; Ping Zhong; Zhensheng Cao; Caroline A David; Xiaoling Xuei; Claude G Lerner; Niru B Soni; Mai-Ha Bui; Linus L Shen; Yingna Cai; Philip J Merta; Anne Y C Saiki; Bruce A Beutel
Novel antibacterial class.
Antimicrobial agents and chemotherapy 2003;47(12):3831-9.
2003: Xenia Beebe; Angela M Nilius; Philip J Merta; Niru B Soni; Mai-Ha Bui; Rolf Wagner; Bruce A Beutel
Synthesis and SAR evaluation of oxadiazolopyrazines as selective Haemophilus influenzae antibacterial agents.
Bioorganic & medicinal chemistry letters 2003;13(19):3133-6.