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Luigi Messori

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Francesca Guidi; Ida Landini; Luca Bini; Angela Casini; Paul J Dyson; Chiara Gabbiani; Enrico Mini; Alessandra Modesti; Stefania Nobili; Michele Puglia; Luigi Messori
The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics.
Chiara Gabbiani; Lara Massai; Elena Michelucci; Federica Scaletti; Maria A Cinellu; Luigi Messori
Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications.
Chiara Gabbiani; Laura Maiore; Lara Massai; Elena Michelucci; Federica Scaletti; Maria A Cinellu; Luigi Messori
Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme.

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2013: Francesca Guidi; Ida Landini; Luca Bini; Angela Casini; Paul J Dyson; Chiara Gabbiani; Enrico Mini; Alessandra Modesti; Stefania Nobili; Michele Puglia; Luigi Messori
The molecular mechanisms of antimetastatic ruthenium compounds explored through DIGE proteomics.
Journal of inorganic biochemistry 2013;118():94-9.
2012: Chiara Gabbiani; Lara Massai; Elena Michelucci; Federica Scaletti; Maria A Cinellu; Luigi Messori
Medicinal gold compounds form tight adducts with the copper chaperone Atox-1: biological and pharmacological implications.
Chemical communications (Cambridge, England) 2012;48(95):11623-5.
2012: Chiara Gabbiani; Laura Maiore; Lara Massai; Elena Michelucci; Federica Scaletti; Maria A Cinellu; Luigi Messori
Protein metalation by metal-based drugs: reactions of cytotoxic gold compounds with cytochrome c and lysozyme.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2012;17(8):1293-302.
2012: Francesca Guidi; Ida Landini; Luca Bini; Maria A Cinellu; Dolores Fregona; Chiara Gabbiani; Tania Gamberi; Enrico Mini; Alessandra Modesti; Pietro Amedeo Modesti; Stefania Nobili; Michele Puglia; Luigi Messori
2D-DIGE analysis of ovarian cancer cell responses to cytotoxic gold compounds.
Molecular bioSystems 2012;8(4):985-93.
2012: Maria Serratrice; Antonio Zucca; Enrico Mini; Stefania Nobili; Maria Pilo; Maria A Cinellu; Chiara Gabbiani; Annalisa Guerri; Ida Landini; Laura Maiore; Luigi Messori
Synthesis, structural characterization, solution behavior, and in vitro antiproliferative properties of a series of gold complexes with 2-(2'-pyridyl)benzimidazole as ligand: comparisons of gold(III) versus gold(I) and mononuclear versus binuclear derivatives.
Inorganic chemistry 2012;51(5):3161-71.
2012: Francesca Guidi; Ida Landini; Francesca Magherini; Luigi Messori; Enrico Mini; Luca Bini; Maria A Cinellu; Tania Fiaschi; Chiara Gabbiani; Stefania Nobili; Michele Puglia; Alessandra Modesti
Proteomic analysis of ovarian cancer cell responses to cytotoxic gold compounds.
Metallomics : integrated biometal science 2012;4(3):307-14.
2012: Laura Maiore; Maria A Cinellu; Chiara Gabbiani; Ida Landini; Enrico Mini; Stefania Nobili; Luigi Messori
Gold(III) complexes with 2-substituted pyridines as experimental anticancer agents: solution behavior, reactions with model proteins, antiproliferative properties.
Journal of inorganic biochemistry 2012;108():123-7.
2011: Nicola Micale; Anna Rosa Sannella; Tanja Schirmeister; Carlo Severini; Maria A Cinellu; Chiara Gabbiani; Laura Maiore; Luigi Messori
Selected gold compounds cause pronounced inhibition of Falcipain 2 and effectively block P. falciparum growth in vitro.
Journal of inorganic biochemistry 2011;105(12):1576-9.
2011: Chiara Gabbiani; Gerhard Kelter; Angela Casini; Maria A Cinellu; Fabio Cocco; Heinz-Herbert Fiebig; Luigi Messori
Mechanistic studies on two dinuclear organogold(III) compounds showing appreciable antiproliferative properties and a high redox stability.
Metallomics : integrated biometal science 2011;3(12):1318-23.
2011: Daniela Valensin; Gianni Valensin; Caterina Migliorini; Chiara Gabbiani; Elena Gaggelli; Henryk Kozlowski; Giovanni La Penna; Luigi Messori
Exploring the reactions of β-amyloid (Aβ) peptide 1-28 with Al(III) and Fe(III) ions.
Inorganic chemistry 2011;50(15):6865-7.
2011: Silvia Bolognin; Luigi Messori; Denise Drago; Chiara Gabbiani; Laura Cendron; Paolo Zatta
Aluminum, copper, iron and zinc differentially alter amyloid-Aβ(1-42) aggregation and toxicity.
The international journal of biochemistry & cell biology 2011;43(6):877-85.
2011: Laura Maiore; Maria A Cinellu; Elena Michelucci; Gloriano Moneti; Stefania Nobili; Ida Landini; Enrico Mini; Annalisa Guerri; Chiara Gabbiani; Luigi Messori
Structural and solution chemistry, protein binding and antiproliferative profiles of gold(I)/(III) complexes bearing the saccharinato ligand.
Journal of inorganic biochemistry 2011;105(3):348-55.
2011: Luigi Messori; A Balerna; I Ascone; C Castellano; Chiara Gabbiani; Angela Casini; C Marchioni; G Jaouen; A Congiu Castellano
X-ray absorption spectroscopy studies of the adducts formed between cytotoxic gold compounds and two major serum proteins.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2011;16(3):491-9.
2011: Angela Casini; Luigi Messori
Molecular mechanisms and proposed targets for selected anticancer gold compounds.
Current topics in medicinal chemistry 2011;11(21):2647-60.
2011: Francesca Sorrentino; Anastasia Karioti; Paola Gratteri; Maria Pia Rigobello; Guido Scutari; Luigi Messori; Alberto Bindoli; Matteo Chioccioli; Chiara Gabbiani; Maria Camilla Bergonzi; Anna Rita Bilia
Hypericins and thioredoxin reductase: Biochemical and docking studies disclose the molecular basis for effective inhibition by naphthodianthrones.
Bioorganic & medicinal chemistry 2011;19(1):631-41.
2010: Angela Casini; Claudia Temperini; Chiara Gabbiani; Claudiu T Supuran; Luigi Messori
The x-ray structure of the adduct between NAMI-A and carbonic anhydrase provides insights into the reactivity of this metallodrug with proteins.
ChemMedChem 2010;5(12):1989-94.
2010: Alessandro Pratesi; Chiara Gabbiani; Mauro Ginanneschi; Luigi Messori
Reactions of medicinally relevant gold compounds with the C-terminal motif of thioredoxin reductase elucidated by MS analysis.
Chemical communications (Cambridge, England) 2010;46(37):7001-3.
2010: Gabriella Tamasi; Mario Casolaro; Agnese Magnani; Alessandro Sega; Luisa Chiasserini; Luigi Messori; Chiara Gabbiani; Seied Mojtaba Valiahdi; Michael A Jakupec; Bernhard K Keppler; Michael B Hursthouse; Renzo Cini
New platinum-oxicam complexes as anti-cancer drugs. Synthesis, characterization, release studies from smart hydrogels, evaluation of reactivity with selected proteins and cytotoxic activity in vitro.
Journal of inorganic biochemistry 2010;104(8):799-814.
2010: Angela Casini; Fabio Edafe; Mikael Erlandsson; Luca Gonsalvi; Antonella Ciancetta; Nazzareno Re; Andrea Ienco; Luigi Messori; Maurizio Peruzzini; Paul J Dyson
Rationalization of the inhibition activity of structurally related organometallic compounds against the drug target cathepsin B by DFT.
Dalton transactions (Cambridge, England : 2003) 2010;39(23):5556-63.
2010: Daniela Valensin; Paolo Anzini; Elena Gaggelli; Nicola Gaggelli; Gabriella Tamasi; Renzo Cini; Chiara Gabbiani; Elena Michelucci; Luigi Messori; Henryk Kozlowski; Gianni Valensin
fac-{Ru(CO)(3)}(2+) selectively targets the histidine residues of the beta-amyloid peptide 1-28. Implications for new Alzheimer's disease treatments based on ruthenium complexes.
Inorganic chemistry 2010;49(11):4720-2.
2010: Chiara Gabbiani; Francesca Magherini; Alessandra Modesti; Luigi Messori
Proteomic and metallomic strategies for understanding the mode of action of anticancer metallodrugs.
Anti-cancer agents in medicinal chemistry 2010;10(4):324-37.
2010: Francesca Magherini; Alessandra Modesti; Luca Bini; Michele Puglia; Ida Landini; Stefania Nobili; Enrico Mini; Maria Agostina Cinellu; Chiara Gabbiani; Luigi Messori
Exploring the biochemical mechanisms of cytotoxic gold compounds: a proteomic study.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(4):573-82.
2010: Stefania Nobili; Enrico Mini; Ida Landini; Chiara Gabbiani; Angela Casini; Luigi Messori
Gold compounds as anticancer agents: chemistry, cellular pharmacology, and preclinical studies.
Medicinal research reviews 2010;30(3):550-80.
2010: Pasquale Mura; Mercedes Camalli; Angela Casini; Chiara Gabbiani; Luigi Messori
Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B.
Journal of inorganic biochemistry 2010;104(2):111-7.
2010: Massimo Innocenti; Emanuele Salvietti; Martina Guidotti; Angela Casini; Silvano Bellandi; Maria Luisa Foresti; Chiara Gabbiani; Andrea Pozzi; Paolo Zatta; Luigi Messori
Trace copper(II) or zinc(II) ions drastically modify the aggregation behavior of amyloid-beta1-42: an AFM study.
Journal of Alzheimer's disease : JAD 2010;19(4):1323-9.
2009: Angela Casini; Andrei Karotki; Chiara Gabbiani; Francesco Rugi; Milan Vašák; Luigi Messori; Paul J Dyson
Reactivity of an antimetastatic organometallic ruthenium compound with metallothionein-2: relevance to the mechanism of action.
Metallomics : integrated biometal science 2009;1(5):434-41.
2009: Angela Casini; Gerhard Kelter; Chiara Gabbiani; Maria Agostina Cinellu; Giovanni Minghetti; Dolores Fregona; Heinz-Herbert Fiebig; Luigi Messori
Chemistry, antiproliferative properties, tumor selectivity, and molecular mechanisms of novel gold(III) compounds for cancer treatment: a systematic study.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2009;14(7):1139-49.
2009: Silvia Bolognin; Denise Drago; Luigi Messori; Paolo Zatta
Chelation therapy for neurodegenerative diseases.
Medicinal research reviews 2009;29(4):547-70.
2009: Justyna Brasuń; Agnieszka Matera-Witkiewicz; Stanisław Ołdziej; Alessandro Pratesi; Mauro Ginanneschi; Luigi Messori
Impact of ring size on the copper(II) coordination abilities of cyclic tetrapeptides.
Journal of inorganic biochemistry 2009;103(5):813-7.
2009: Agnieszka Matera-Witkiewicz; Justyna Brasuń; Jolanta Swiatek-Kozłowska; Alessandro Pratesi; Mauro Ginanneschi; Luigi Messori
Short-chain oligopeptides with copper(II) binding properties: The impact of specific structural modifications on the copper(II) coordination abilities.
Journal of inorganic biochemistry 2009;103(5):678-88.
2009: Chiara Gabbiani; Luigi Messori; Maria A Cinellu; Angela Casini; Pasquale Mura; Anna R Sannella; Carlo Severini; Giancarlo Majori; Anna R Bilia; Franco F Vincieri
Outstanding plasmodicidal properties within a small panel of metallic compounds: Hints for the development of new metal-based antimalarials.
Journal of inorganic biochemistry 2009;103(2):310-2.
2009: Silvia Bolognin; Luigi Messori; Paolo Zatta
Metal ion physiopathology in neurodegenerative disorders.
Neuromolecular medicine 2009;11(4):223-38.
2009: Cristina Grossi; Simona Francese; Angela Casini; Maria Cristina Rosi; Ilaria Luccarini; Anna Fiorentini; Chiara Gabbiani; Luigi Messori; Gloriano Moneti; Fiorella Casamenti
Clioquinol decreases amyloid-beta burden and reduces working memory impairment in a transgenic mouse model of Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2009;17(2):423-40.
2008: Angela Casini; Chiara Gabbiani; Francesca Sorrentino; Maria Pia Rigobello; Alberto Bindoli; Tilmann J Geldbach; Alessandro Marrone; Nazzareno Re; Christian G. Hartinger; Paul J Dyson; Luigi Messori
Emerging protein targets for anticancer metallodrugs: inhibition of thioredoxin reductase and cathepsin B by antitumor ruthenium(II)-arene compounds.
Journal of medicinal chemistry 2008;51(21):6773-81.
2008: Chiara Gabbiani; Angela Casini; Guido Mastrobuoni; Noam Kirshenbaum; Ofra Moshel; Giuseppe Pieraccini; Gloriano Moneti; Luigi Messori; Dan Gibson
Peculiar mechanistic and structural features of the carboplatin-cytochrome c system revealed by ESI-MS analysis.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2008;13(5):755-64.
2008: Angela Casini; Annalisa Guerri; Chiara Gabbiani; Luigi Messori
Biophysical characterisation of adducts formed between anticancer metallodrugs and selected proteins: new insights from X-ray diffraction and mass spectrometry studies.
Journal of inorganic biochemistry 2008;102(5-6):995-1006.
2008: Chiara Gabbiani; Angela Casini; Luigi Messori; Annalisa Guerri; Maria Agostina Cinellu; Giovanni Minghetti; Maddalena Corsini; Claudia Rosani; Piero Zanello; Massimiliano Arca
Structural characterization, solution studies, and DFT calculations on a series of binuclear gold(III) oxo complexes: relationships to biological properties.
Inorganic chemistry 2008;47(7):2368-79.
2008: Anna Rosa Sannella; Angela Casini; Chiara Gabbiani; Luigi Messori; Anna Rita Bilia; Francesco Franco Vincieri; Giancarlo Majori; Carlo Severini
New uses for old drugs. Auranofin, a clinically established antiarthritic metallodrug, exhibits potent antimalarial effects in vitro: Mechanistic and pharmacological implications.
FEBS letters 2008;582(6):844-7.
2008: Angela Casini; Christian G. Hartinger; Chiara Gabbiani; Enrico Mini; Paul J Dyson; Bernard K Keppler; Luigi Messori
Gold(III) compounds as anticancer agents: relevance of gold-protein interactions for their mechanism of action.
Journal of inorganic biochemistry 2008;102(3):564-75.
2008: Denise Drago; Mikol Bettella; Silvia Bolognin; Laura Cendron; Janez Scancar; Radmila Milacic; Fernanda Ricchelli; Angela Casini; Luigi Messori; Giuseppe Tognon; Paolo Zatta
Potential pathogenic role of beta-amyloid(1-42)-aluminum complex in Alzheimer's disease.
The international journal of biochemistry & cell biology 2008;40(4):731-46.
2007: Pasquale Mura; Mercedes Camalli; Alberto Bindoli; Francesca Sorrentino; Angela Casini; Chiara Gabbiani; Maddalena Corsini; Piero Zanello; Maria Pia Rigobello; Luigi Messori
Activity of rat cytosolic thioredoxin reductase is strongly decreased by trans-[bis(2-amino-5- methylthiazole)tetrachlororuthenate(III)]: first report of relevant thioredoxin reductase inhibition for a ruthenium compound.
Journal of medicinal chemistry 2007;50(24):5871-4.
2007: Alessandro Pratesi; Piero Zanello; Gianluca Giorgi; Luigi Messori; Franco Laschi; Angela Casini; Maddalena Corsini; Chiara Gabbiani; Marco Orfei; Claudia Rosani; Mauro Ginanneschi
New copper(II)/cyclic tetrapeptide system that easily oxidizes to copper(III) under atmospheric oxygen.
Inorganic chemistry 2007;46(24):10038-40.
2007: Angela Casini; Guido Mastrobuoni; Mattia Terenghi; Chiara Gabbiani; Enrico Monzani; Gloriano Moneti; Luigi Casella; Luigi Messori
Ruthenium anticancer drugs and proteins: a study of the interactions of the ruthenium(III) complex imidazolium trans-[tetrachloro(dimethyl sulfoxide)(imidazole)ruthenate(III)] with hen egg white lysozyme and horse heart cytochrome c.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2007;12(8):1107-17.
2007: Angela Casini; Chiara Gabbiani; Guido Mastrobuoni; Raffaella Zoe Pellicani; Francesco Paolo Intini; Fabio Arnesano; Giovanni Natile; Gloriano Moneti; Simona Francese; Luigi Messori
Insights into the molecular mechanisms of protein platination from a case study: the reaction of anticancer platinum(II) iminoethers with horse heart cytochrome c.
Biochemistry 2007;46(43):12220-30.
2007: Luigi Messori; Angela Casini; Chiara Gabbiani; Lorenzo Sorace; Maurizio Muniz-Miranda; Paolo Zatta
Unravelling the chemical nature of copper cuprizone.
Dalton transactions (Cambridge, England : 2003) 2007;(21):2112-4.
2007: Angela Casini; Guido Mastrobuoni; Wee Han Ang; Chiara Gabbiani; Giuseppe Pieraccini; Gloriano Moneti; Paul J Dyson; Luigi Messori
ESI-MS characterisation of protein adducts of anticancer ruthenium(II)-arene PTA (RAPTA) complexes.
ChemMedChem 2007;2(5):631-5.
2007: Laura Ciani; Angela Casini; Chiara Gabbiani; Sandra Ristori; Luigi Messori; Giacomo Martini
DOTAP/DOPE and DC-Chol/DOPE lipoplexes for gene delivery studied by circular dichroism and other biophysical techniques.
Biophysical chemistry 2007;127(3):213-20.
2007: Justyna Brasuń; Agnieszka Matera; Stanisław Ołdziej; Jolanta Swiatek-Kozłowska; Luigi Messori; Chiara Gabbiani; Marco Orfei; Mauro Ginanneschi
The copper(II) coordination abilities of three novel cyclic tetrapeptides with -His-Xaa-His- motif.
Journal of inorganic biochemistry 2007;101(3):452-60.
2007: Anna Rosa Sannella; Luigi Messori; Angela Casini; Franco Francesco Vincieri; Anna Rita Bilia; Giancarlo Majori; Carlo Severini
Antimalarial properties of green tea.
Biochemical and biophysical research communications 2007;353(1):177-81.
2007: Angela Casini; Guido Mastrobuoni; Claudia Temperini; Chiara Gabbiani; Simona Francese; Gloriano Moneti; Claudiu T Supuran; Andrea Scozzafava; Luigi Messori
ESI mass spectrometry and X-ray diffraction studies of adducts between anticancer platinum drugs and hen egg white lysozyme.
Chemical communications (Cambridge, England) 2007;(2):156-8.
2007: Renzo Cini; Sandra Defazio; Gabriella Tamasi; Mario Casolaro; Luigi Messori; Angela Casini; Margherita Morpurgo; Michael B Hursthouse
fac-{Ru(CO)3}2+-core complexes and design of metal-based drugs. synthesis, structure, and reactivity of Ru-thiazole derivative with serum proteins and absorption-release studies with acryloyl and silica hydrogels as carriers in physiological media.
Inorganic chemistry 2007;46(1):79-92.
2006: Angela Casini; Maria Agostina Cinellu; Giovanni Minghetti; Chiara Gabbiani; Marcella Coronnello; Enrico Mini; Luigi Messori
Structural and solution chemistry, antiproliferative effects, and DNA and protein binding properties of a series of dinuclear gold(III) compounds with bipyridyl ligands.
Journal of medicinal chemistry 2006;49(18):5524-31.
2006: Luigi Messori; Chiara Gabbiani; Angela Casini; Matteo Siragusa; Franco Francesco Vincieri; Anna Rita Bilia
The reaction of artemisinins with hemoglobin: a unified picture.
Bioorganic & medicinal chemistry 2006;14(9):2972-7.
2006: Angela Casini; Chiara Gabbiani; Guido Mastrobuoni; Luigi Messori; Gloriano Moneti; Giuseppe Pieraccini
Exploring metallodrug-protein interactions by ESI mass spectrometry: the reaction of anticancer platinum drugs with horse heart cytochrome c.
ChemMedChem 2006;1(4):413-7.
2005: Marcella Coronnello; Enrico Mini; Barbara Caciagli; Maria Agostina Cinellu; Alberto Bindoli; Chiara Gabbiani; Luigi Messori
Mechanisms of cytotoxicity of selected organogold(III) compounds.
Journal of medicinal chemistry 2005;48(21):6761-5.
2005: Paolo Zatta; Luigi Messori; Pierluigi Mauri; Susan J van Rensburg; Johann van Zyl; Silvia Gabrielli; Chiara Gabbiani
The C2 variant of human serum transferrin retains the iron binding properties of the native protein.
Biochimica et biophysica acta 2005;1741(3):264-70.
2005: Pasquale Mura; Francesca Piccioli; Chiara Gabbiani; Mercedes Camalli; Luigi Messori
Structure-function relationships within Keppler-type antitumor ruthenium(III) complexes: the case of 2-aminothiazolium[trans-tetrachlorobis(2-aminothiazole)ruthenate(III)].
Inorganic chemistry 2005;44(14):4897-9.
2005: Paolo Zatta; Michelangelo Raso; Pamela Zambenedetti; Werner Wittkowski; Luigi Messori; Francesca Piccioli; Pierluigi Mauri; Mariano Beltramini
Copper and zinc dismetabolism in the mouse brain upon chronic cuprizone treatment.
Cellular and molecular life sciences : CMLS 2005;62(13):1502-13.
2005: Mario Suwalsky; Fernando Villena; Beryl Norris; Marco Soto-Arriaza; Carlos P Sotomayor; Luigi Messori; Paolo Zatta
Structural effects of titanium citrate on the human erythrocyte membrane.
Journal of inorganic biochemistry 2005;99(3):764-70.
2005: Luigi Messori; Giordana Marcon; Alessio Innocenti; Enzo Gallori; Marco Franchi; Pierluigi Orioli
Molecular recognition of metal complexes by DNA: a comparative study of the interactions of the parent complexes [PtCl(TERPY)]Cl and [AuCl(TERPY)]Cl2 with double stranded DNA.
Bioinorganic chemistry and applications 2005;():239-53.
2004: Mario Suwalsky; Pamela Zambenedetti; Emilio Carpené; Meryem Ibnlkayat; Werner Wittkowski; Luigi Messori; Paolo Zatta
Effects of chronic treatment with sodium tetrachloroaurate(III) in mice and membrane models.
Journal of inorganic biochemistry 2004;98(12):2080-6.
2004: Justyna Brasun; Chiara Gabbiani; Mauro Ginanneschi; Luigi Messori; Marco Orfei; Jolanta Swiatek-Kozlowska
The copper(II) binding properties of the cyclic peptide c(HGHK).
Journal of inorganic biochemistry 2004;98(12):2016-21.
2004: Luigi Messori; Giordana Marcon; Maria Agostina Cinellu; Marcella Coronnello; Enrico Mini; Chiara Gabbiani; Pierluigi Orioli
Solution chemistry and cytotoxic properties of novel organogold(III) compounds.
Bioorganic & medicinal chemistry 2004;12(23):6039-43.
2004: Maria Pia Rigobello; Luigi Messori; Giordana Marcon; Maria Agostina Cinellu; Marcantonio Bragadin; Alessandra Folda; Guido Scutari; Alberto Bindoli
Gold complexes inhibit mitochondrial thioredoxin reductase: consequences on mitochondrial functions.
Journal of inorganic biochemistry 2004;98(10):1634-41.
2004: Pasquale Mura; Mercedes Camalli; Luigi Messori; Francesca Piccioli; Piero Zanello; Maddalena Corsini
Synthesis, structural characterization, solution chemistry, and preliminary biological studies of the ruthenium(III) complexes [TzH][trans-RuCl4(Tz)2] and [TzH][trans-RuCl4(DMSO)(Tz)].(DMSO), the thiazole analogues of antitumor ICR and NAMI-A.
Inorganic chemistry 2004;43(13):3863-70.
2004: Massimo Di Vaira; Carla Bazzicalupi; Pierluigi Orioli; Luigi Messori; Bruno Bruni; Paolo Zatta
Clioquinol, a drug for Alzheimer's disease specifically interfering with brain metal metabolism: structural characterization of its zinc(II) and copper(II) complexes.
Inorganic chemistry 2004;43(13):3795-7.
2004: Francesca Piccioli; S Sabatini; Luigi Messori; Pierluigi Orioli; Christian G. Hartinger; B K Keppler
A comparative study of adduct formation between the anticancer ruthenium(III) compound HInd trans-[RuCl4(Ind)2] and serum proteins.
Journal of inorganic biochemistry 2004;98(6):1135-42.
2004: Cristina Capanni; Niccolò Taddei; Silvia Gabrielli; Luigi Messori; Pierluigi Orioli; Fabrizio Chiti; Massimo Stefani; Giampietro Ramponi
Investigation of the effects of copper ions on protein aggregation using a model system.
Cellular and molecular life sciences : CMLS 2004;61(7-8):982-91.
2004: Luigi Messori; Giordana Marcon
Gold complexes in the treatment of rheumatoid arthritis.
Metal ions in biological systems 2004;41():279-304.
2004: Luigi Messori; Giordana Marcon
Gold complexes as antitumor agents.
Metal ions in biological systems 2004;42():385-424.
2003: Renzo Cini; Gabriella Tamasi; Sandra Defazio; Maddalena Corsini; Piero Zanello; Luigi Messori; Giordana Marcon; Francesca Piccioli; Pierluigi Orioli
Study of ruthenium(II) complexes with anticancer drugs as ligands. Design of metal-based phototherapeutic agents.
Inorganic chemistry 2003;42(24):8038-52.
2003: Giordana Marcon; Luigi Messori; Pierluigi Orioli; Maria Agostina Cinellu; Giovanni Minghetti
Reactions of gold(III) complexes with serum albumin.
European journal of biochemistry / FEBS 2003;270(23):4655-61.
2003: Luigi Messori; Francesca Piccioli; Brigitte Eitler; Maria Camilla Bergonzi; Anna Rita Bilia; Franco Francesco Vincieri
Spectrophotometric and ESI-MS/HPLC studies reveal a common mechanism for the reaction of various artemisinin analogues with hemin.
Bioorganic & medicinal chemistry letters 2003;13(22):4055-7.
2003: Alberta Bergamo; Luigi Messori; Francesca Piccioli; Moreno Cocchietto; Gianni Sava
Biological role of adduct formation of the ruthenium(III) complex NAMI-A with serum albumin and serum transferrin.
Investigational new drugs 2003;21(4):401-11.
2003: Marco Orfei; Maria Claudia Alcaro; Giordana Marcon; Mario Chelli; Mauro Ginanneschi; Henryk Kozlowski; Justyna Brasuń; Luigi Messori
Modeling of copper(II) sites in proteins based on histidyl and glycyl residues.
Journal of inorganic biochemistry 2003;97(3):299-307.
2003: Luigi Messori; Jiajiu Shaw; Mercedes Camalli; Pasquale Mura; Giordana Marcon
Structural features of a new dinuclear platinum(II) complex with significant antiproliferative activity.
Inorganic chemistry 2003;42(20):6166-8.
2003: Massimo Di Vaira; Pierluigi Orioli; Francesca Piccioli; Bruno Bruni; Luigi Messori
Structure of a terbium(III)-quinizarine complex: the first crystallographic model for metalloanthracyclines.
Inorganic chemistry 2003;42(10):3157-9.
2003: Lucia Morbidelli; Sandra Donnini; Sandra Filippi; Luigi Messori; Francesca Piccioli; Pierluigi Orioli; Gianni Sava; Marina Ziche
Antiangiogenic properties of selected ruthenium(III) complexes that are nitric oxide scavengers.
British journal of cancer 2003;88(9):1484-91.
2003: Luigi Messori; Giordana Marcon; Pierluigi Orioli; Marco Fontani; Piero Zanello; Alberta Bergamo; Gianni Sava; Pasquale Mura
Molecular structure, solution chemistry and biological properties of the novel [ImH][trans-IrCl(4)(Im)(DMSO)], (I) and of the orange form of [(DMSO)(2)H][trans-IrCl(4)(DMSO)(2)], (II), complexes.
Journal of inorganic biochemistry 2003;95(1):37-46.
2003: Claudia Temperini; Luigi Messori; Pierluigi Orioli; Cristina Di Bugno; Fabio Animati; Giovanni Ughetto
The crystal structure of the complex between a disaccharide anthracycline and the DNA hexamer d(CGATCG) reveals two different binding sites involving two DNA duplexes.
Nucleic acids research 2003;31(5):1464-9.
2003: Luigi Messori; Giordana Marcon; Pierluigi Orioli
Gold(III) compounds as new family of anticancer drugs.
Bioinorganic chemistry and applications 2003;():177-87.
2002: Luigi Messori; Francesca Piccioli; Silvia Gabrielli; Pierluigi Orioli; Leonardo Angeloni; Cristina Di Bugno
The disaccharide anthracycline MEN 10755 binds human serum albumin to a non-classical drug binding site.
Bioorganic & medicinal chemistry 2002;10(11):3425-30.
2002: Pierluigi Orioli; Bruno Bruni; Massimo Di Vaira; Luigi Messori; Francesca Piccioli
Decomposition of ascorbic acid in the presence of cadmium ions leads to formation of a polymeric cadmium oxalate species with peculiar structural features.
Inorganic chemistry 2002;41(17):4312-4.
2002: Giordana Marcon; Luigi Messori; Pierluigi Orioli
Gold(III) complexes as a new family of cytotoxic and antitumor agents.
Expert review of anticancer therapy 2002;2(3):337-46.
2002: Mario Casolaro; Mario Chelli; Mauro Ginanneschi; Franco Laschi; Luigi Messori; Maurizio Muniz-Miranda; Anna Maria Papini; Teresa Kowalik-Jankowska; Henryk Kozlowski
Spectroscopic and potentiometric study of the SOD mimic system copper(II)/acetyl-L-histidylglycyl-L-histidylglycine.
Journal of inorganic biochemistry 2002;89(3-4):181-90.
2002: Giordana Marcon; Stefania Carotti; Marcella Coronnello; Luigi Messori; Enrico Mini; Pierluigi Orioli; Teresita Mazzei; Maria Agostina Cinellu; Giovanni Minghetti
Gold(III) complexes with bipyridyl ligands: solution chemistry, cytotoxicity, and DNA binding properties.
Journal of medicinal chemistry 2002;45(8):1672-7.
2002: Luigi Messori; Francesco Abbate; Pierluigi Orioli; Caterina Tempi; Giordana Marcon
Au2trien: a dinuclear gold(III) complex with unprecedented structura features.
Chemical communications (Cambridge, England) 2002;(6):612-3.
2002: Anna Rita Bilia; Diamanto Lazari; Luigi Messori; Vania Taglioli; Claudia Temperini; Franco Francesco Vincieri
Simple and rapid physico-chemical methods to examine action of antimalarial drugs with hemin: its application to Artemisia annua constituents.
Life sciences 2002;70(7):769-78.
2001: A Casini; Luigi Messori; Pierluigi Orioli; M Gielen; M Kemmer; Rudolph Willem
Interactions of two cytotoxic organotin(IV) compounds with calf thymus DNA.
Journal of inorganic biochemistry 2001;85(4):297-300.
2001: Luigi Messori; Claudia Temperini; Francesca Piccioli; Fabio Animati; Cristina Di Bugno; Pierluigi Orioli
Solution chemistry and DNA binding properties of MEN 10755, a novel disaccharide analogue of doxorubicin.
Bioorganic & medicinal chemistry 2001;9(7):1815-25.
2001: Luigi Messori; Pierluigi Orioli; C Tempi; Giordana Marcon
Interactions of selected gold(III) complexes with calf thymus DNA.
Biochemical and biophysical research communications 2001;281(2):352-60.
2000: Luigi Messori; Francesco Abbate; Giordana Marcon; Pierluigi Orioli; Marco Fontani; Enrico Mini; Teresita Mazzei; Stefania Carotti; T O'Connell; Piero Zanello
Gold(III) complexes as potential antitumor agents: solution chemistry and cytotoxic properties of some selected gold(III) compounds.
Journal of medicinal chemistry 2000;43(19):3541-8.
2000: Enzo Gallori; Cristina Vettori; Enzo Alessio; F G Vilchez; Rosario A Vilaplana; Pierluigi Orioli; Angela Casini; Luigi Messori
DNA as a possible target for antitumor ruthenium(III) complexes.
Archives of biochemistry and biophysics 2000;376(1):156-62.
2000: Stefania Carotti; Giordana Marcon; M Marussich; Teresita Mazzei; Luigi Messori; Enrico Mini; Pierluigi Orioli
Cytotoxicity and DNA binding properties of a chloro glycylhistidinate gold(III) complex (GHAu).
Chemico-biological interactions 2000;125(1):29-38.
2000: Luigi Messori; Pierluigi Orioli; D Vullo; Enzo Alessio; Elisabetta Iengo
A spectroscopic study of the reaction of NAMI, a novel ruthenium(III)anti-neoplastic complex, with bovine serum albumin.
European journal of biochemistry / FEBS 2000;267(4):1206-13.
2000: Luigi Messori; F G Vilchez; Rosario A Vilaplana; Francesca Piccioli; Enzo Alessio; B Keppler
Binding of Antitumor Ruthenium(III) Complexes to Plasma Proteins.
Metal-based drugs 2000;7(6):335-42.
2000: Marcella Coronnello; Giordana Marcon; Stefania Carotti; Barbara Caciagli; Enrico Mini; Teresita Mazzei; Pierluigi Orioli; Luigi Messori
Cytotoxicity, DNA damage, and cell cycle perturbations induced by two representative gold(III) complexes in human leukemic cells with different cisplatin sensitivity.
Oncology research 2000;12(9-10):361-70.
1999: P C Rodrigues; U Beyer; P Schumacher; Thomas Roth; Heinz-Herbert Fiebig; Clemens Unger; Luigi Messori; Pierluigi Orioli; Dietrich Paper; Rolf Mülhaupt; Felix Kratz
Acid-sensitive polyethylene glycol conjugates of doxorubicin: preparation, in vitro efficacy and intracellular distribution.
Bioorganic & medicinal chemistry 1999;7(11):2517-24.
1999: Luigi Messori; Pierluigi Orioli; V Banholzer; I Pais; Paolo Zatta
Formation of titanium(IV) transferrin by reaction of human serum apotransferrin with titanium complexes.
FEBS letters 1999;442(2-3):157-61.
1998: F Gonzalez Vilchez; Rosario A Vilaplana; G Blasco; Luigi Messori
Solution studies of the antitumor complex dichloro 1,2-propylendiaminetetraacetate ruthenium (III) and of its interactions with proteins.
Journal of inorganic biochemistry 1998;71(1-2):45-51.
1998: P Calamai; Stefania Carotti; Annalisa Guerri; Teresita Mazzei; Luigi Messori; Enrico Mini; Pierluigi Orioli; G P Speroni
Cytotoxic effects of gold(III) complexes on established human tumor cell lines sensitive and resistant to cisplatin.
Anti-cancer drug design 1998;13(1):67-80.
1997: Luigi Messori; G D Poggetto; R Monnanni; J Hirose
The pH dependent properties of metallotransferrins: a comparative study.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1997;10(4):303-13.
1997: P Calamai; Stefania Carotti; Annalisa Guerri; Luigi Messori; Enrico Mini; Pierluigi Orioli; G P Speroni
Biological properties of two gold(III) complexes: AuCl3(Hpm) and AuCl2(pm).
Journal of inorganic biochemistry 1997;66(2):103-9.
1996: Luigi Messori; Felix Kratz; Enzo Alessio
The Interaction of the Antitumor Complexes Na[trans-RuCl(4) (DMSO)(Im)] and Na[trans-RuCl(4)(DMSO)(Ind)] With Apotransferrin: a Spectroscopic Study.
Metal-based drugs 1996;3(1):1-9.
1995: Gianantonio Battistuzzi; L Calzolai; Luigi Messori; Marco Sola
Metal-induced conformational heterogeneity of transferrins: a spectroscopic study of indium(III) and other metal(III)-substituted transferrins.
Biochemical and biophysical research communications 1995;206(1):161-70.
1994: L Calzolai; Luigi Messori; R Monnanni
The pH dependent spectral properties of Clostridium pasteurianum 2[Fe4S4] ferredoxin.
FEBS letters 1994;350(1):41-5.
1994: Stefano Mangani; Pierluigi Orioli; Andrea Scozzafava; Luigi Messori; P Carloni
EXAFS studies of Fe(III)-phosvitin at high metal to protein ratios.
Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 1994;7(2):104-8.
1994: Felix Kratz; M Hartmann; B Keppler; Luigi Messori
The binding properties of two antitumor ruthenium(III) complexes to apotransferrin.
The Journal of biological chemistry 1994;269(4):2581-8.
1993: Ivano Bertini; Fabrizio Briganti; L Calzolai; Luigi Messori; Andrea Scozzafava
Selective interaction of ferricyanide with cluster I of Clostridium pasteurianum 2[Fe4S4] ferredoxin.
FEBS letters 1993;332(3):268-72.
1993: Felix Kratz; Luigi Messori
Spectral characterization of ruthenium (III) transferrin.
Journal of inorganic biochemistry 1993;49(2):79-82.
1993: Ivano Bertini; Claudio Luchinat; Luigi Messori; M Vasak
A two-dimensional NMR study of Co(II)7 rabbit liver metallothionein.
European journal of biochemistry / FEBS 1993;211(1-2):235-40.
1992: D S Auld; Ivano Bertini; Antonio Donaire; Luigi Messori; José-María Moratal
pH-dependent properties of cobalt(II) carboxypeptidase A-inhibitor complexes.
Biochemistry 1992;31(15):3840-6.
1992: Ivano Bertini; Fabrizio Briganti; Claudio Luchinat; Luigi Messori; R Monnanni; Andrea Scozzafava; G Vallini
1H-NMR studies on partially and fully reduced 2(4Fe-4S) ferredoxin from Clostridium pasteurianum.
European journal of biochemistry / FEBS 1992;204(2):831-9.
1991: Ivano Bertini; Fabrizio Briganti; Claudio Luchinat; Luigi Messori; R Monnanni; Andrea Scozzafava; G Vallini
2D 1H NMR studies of oxidized 2(Fe4S4) ferredoxin from Clostridium pasteurianum.
FEBS letters 1991;289(2):253-6.
1991: Luigi Messori; Mario Piccioli
1H NMR studies on lanthanides substituted transferrins.
Journal of inorganic biochemistry 1991;42(3):185-90.
1989: Ivano Bertini; J Hirose; Luigi Messori; R Monnanni
A 1H NMR study of cobalt(II) arsanilazocarboxypeptidase A.
Journal of inorganic biochemistry 1989;35(3):225-30.
1988: Ivano Bertini; Claudio Luchinat; Luigi Messori; R Monnanni; D S Auld; J F Riordan
1H NMR spectroscopic characterization of binary and ternary complexes of cobalt(II) carboxypeptidase A with inhibitors.
Biochemistry 1988;27(22):8318-25.
1986: Ivano Bertini; Claudio Luchinat; Luigi Messori; R Monnanni; Andrea Scozzafava
The metal-binding properties of ovotransferrin. An investigation of cobalt(II) derivatives.
The Journal of biological chemistry 1986;261(3):1139-46.
1985: Ivano Bertini; Claudio Luchinat; Luigi Messori
Spectral characterization of vanadium-transferrin systems.
Journal of inorganic biochemistry 1985;25(1):57-60.
1984: Ivano Bertini; Claudio Luchinat; Luigi Messori; Andrea Scozzafava
Cobalt(II) as an NMR probe for the investigation of the coordination sites of conalbumin.
European journal of biochemistry / FEBS 1984;141(2):375-8.
1981: Ivano Bertini; Claudio Luchinat; Luigi Messori
A water 17O NMR study of the pH dependent properties of superoxide dismutase.
Biochemical and biophysical research communications 1981;101(2):577-83.