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Nils Metzler-Nolte

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Mingyan Ma; Eckhard Bill; Roland A Fischer; Bernd Mienert; Martin Muhler; Johanna Niesel; Heshmat Noei; Ulrich Schatzschneider; Yuemin Wang; Nils Metzler-Nolte
Iron Metal-Organic Frameworks MIL-88B and NH2 -MIL-88B for the Loading and Delivery of the Gasotransmitter Carbon Monoxide.
Martin Strack; Julia E Bandow; Sina Langklotz; Nils Metzler-Nolte; H Bauke Albada
Silyl-based alkyne-modifying linker for the preparation of C-terminal acetylene-derivatized protected peptides.
Michaela Wenzel; H Bauke Albada; Leendert Hamoen; Bastian Kohl; Nils Metzler-Nolte; Daniela Münch; Nadja Raatschen; Hans-Georg Sahl; Julia E Bandow
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane.

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2013: Mingyan Ma; Eckhard Bill; Roland A Fischer; Bernd Mienert; Martin Muhler; Johanna Niesel; Heshmat Noei; Ulrich Schatzschneider; Yuemin Wang; Nils Metzler-Nolte
Iron Metal-Organic Frameworks MIL-88B and NH2 -MIL-88B for the Loading and Delivery of the Gasotransmitter Carbon Monoxide.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(21):6785-90.
2012: Martin Strack; Julia E Bandow; Sina Langklotz; Nils Metzler-Nolte; H Bauke Albada
Silyl-based alkyne-modifying linker for the preparation of C-terminal acetylene-derivatized protected peptides.
The Journal of organic chemistry 2012;77(22):9954-8.
2012: Michaela Wenzel; H Bauke Albada; Leendert Hamoen; Bastian Kohl; Nils Metzler-Nolte; Daniela Münch; Nadja Raatschen; Hans-Georg Sahl; Julia E Bandow
Proteomic response of Bacillus subtilis to lantibiotics reflects differences in interaction with the cytoplasmic membrane.
Antimicrobial agents and chemotherapy 2012;56(11):5749-57.
2012: Annika Gross; Nina Hüsken; Ingo Ott; Julia Schur; Łukasz Raszeja; Nils Metzler-Nolte
A ruthenocene-PNA bioconjugate--synthesis, characterization, cytotoxicity, and AAS-detected cellular uptake.
Bioconjugate chemistry 2012;23(9):1764-74.
2012: Benjamin Fränzel; Christian Frese; Nils Metzler-Nolte; Maya Penkova; Dirk Andreas Wolters
Escherichia coli exhibits a membrane-related response to a small arginine- and tryptophan-rich antimicrobial peptide.
Proteomics 2012;12(14):2319-30.
2012: H Bauke Albada; Ingrid Dijkgraaf; Jessica H Harvey; Nils Metzler-Nolte; Raphael Stoll; Jennifer L Whistler; Florian Wieberneit; Richard H Fish
The chemoselective reactions of tyrosine-containing G-protein-coupled receptor peptides with [Cp*Rh(H2O)3](OTf)2, including 2D NMR structures and the biological consequences.
Journal of the American Chemical Society 2012;134(25):10321-4.
2012: Malay Patra; Gilles Gasser; Nils Metzler-Nolte
Small organometallic compounds as antibacterial agents.
Dalton transactions (Cambridge, England : 2003) 2012;41(21):6350-8.
2012: Gilles Gasser; Nils Metzler-Nolte
The potential of organometallic complexes in medicinal chemistry.
Current opinion in chemical biology 2012;16(1-2):84-91.
2012: Sergey Abramkin; Markus Galanski; Michael A Jakupec; Nils Metzler-Nolte; Seied M Valiahdi; Bernhard K Keppler
Solid-phase synthesis of oxaliplatin-TAT peptide bioconjugates.
Dalton transactions (Cambridge, England : 2003) 2012;41(10):3001-5.
2012: Luca Gaviglio; Annika Gross; Nils Metzler-Nolte; Mauro Ravera
Synthesis and in vitro cytotoxicity of cis,cis,trans-diamminedichloridodisuccinatoplatinum(IV)-peptide bioconjugates.
Metallomics : integrated biometal science 2012;4(3):260-6.
2012: Gilles Gasser; Rolf Heumann; Klaus Merz; Sebastian Neumann; Antonio Pinto; Michael Seitz; Anna M Sosniak; Nils Metzler-Nolte
Synthesis, characterisation and bioimaging of a fluorescent rhenium-containing PNA bioconjugate.
Dalton transactions (Cambridge, England : 2003) 2012;41(8):2304-13.
2012: Malay Patra; Klaus Merz; Nils Metzler-Nolte
Planar chiral (η6-arene)Cr(CO)3 containing carboxylic acid derivatives: synthesis and use in the preparation of organometallic analogues of the antibiotic platensimycin.
Dalton transactions (Cambridge, England : 2003) 2012;41(1):112-7.
2012: H Bauke Albada; Julia E Bandow; Alina-Iulia Chiriac; Maya Penkova; Hans-Georg Sahl; Michaela Wenzel; Nils Metzler-Nolte
Modulating the activity of short arginine-tryptophan containing antibacterial peptides with N-terminal metallocenoyl groups.
Beilstein journal of organic chemistry 2012;8():1753-64.
2011: Malay Patra; Nils Metzler-Nolte
Azidomethyl-ruthenocene: facile synthesis of a useful metallocene derivative and its application in the 'click' labelling of biomolecules.
Chemical communications (Cambridge, England) 2011;47(41):11444-6.
2011: Nina Hüsken; Fabio La Mantia; Magdalena Gębala; Wolfgang Schuhmann; Nils Metzler-Nolte
Mechanistic studies of Fc-PNA(⋅DNA) surface dynamics based on the kinetics of electron-transfer processes.
Chemistry (Weinheim an der Bergstrasse, Germany) 2011;17(35):9678-90.
2011: Gilles Gasser; Anna M Sosniak; Nils Metzler-Nolte
Metal-containing peptide nucleic acid conjugates.
Dalton transactions (Cambridge, England : 2003) 2011;40(27):7061-76.
2011: Michaela Wenzel; Malay Patra; Dirk Albrecht; David Y-K Chen; K C Nicolaou; Nils Metzler-Nolte; Julia E Bandow
Proteomic signature of fatty acid biosynthesis inhibition available for in vivo mechanism-of-action studies.
Antimicrobial agents and chemotherapy 2011;55(6):2590-6.
2011: Bo Liu; Mingyan Ma; Nils Metzler-Nolte; Christof Wöll; Kirill Yusenko; Denise Zacher; Angelique Bétard; Roland A Fischer
Chemistry of SURMOFs: layer-selective installation of functional groups and post-synthetic covalent modification probed by fluorescence microscopy.
Journal of the American Chemical Society 2011;133(6):1734-7.
2011: Annika Gross; Merja Neukamm; Nils Metzler-Nolte
Synthesis and cytotoxicity of a bimetallic ruthenocene dicobalt-hexacarbonyl alkyne peptide bioconjugate.
Dalton transactions (Cambridge, England : 2003) 2011;40(6):1382-6.
2011: Lukasz Raszeja; Abdelouahid Maghnouj; Stephan Hahn; Nils Metzler-Nolte
A novel organometallic ReI complex with favourable properties for bioimaging and applicability in solid-phase peptide synthesis.
Chembiochem : a European journal of chemical biology 2011;12(3):371-6.
2011: Johannes Zagermann; Mariusz Molon; Nils Metzler-Nolte
Microwave-assisted synthesis of the Tp sandwich compound TpRu(p-Br-C6H4Tp) and application of its benzoic acid derivative TpRu(p-(CO2H)-C6H4Tp) in the covalent labelling of biomolecules.
Dalton transactions (Cambridge, England : 2003) 2011;40(5):1011-5.
2011: Gilles Gasser; Ingo Ott; Nils Metzler-Nolte
Organometallic anticancer compounds.
Journal of medicinal chemistry 2011;54(1):3-25.
2010: Gilles Gasser; Katrin Jäger; Martin Zenker; Ralf Bergmann; Jörg Steinbach; Holger Stephan; Nils Metzler-Nolte
Preparation, 99mTc-labeling and biodistribution studies of a PNA oligomer containing a new ligand derivative of 2,2'-dipicolylamine.
Journal of inorganic biochemistry 2010;104(11):1133-40.
2010: Benjamin Fränzel; Christian Frese; Maya Penkova; Nils Metzler-Nolte; Julia E Bandow; Dirk Wolters
Corynebacterium glutamicum exhibits a membrane-related response to a small ferrocene-conjugated antimicrobial peptide.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2010;15(8):1293-303.
2010: Carsten Kötting; Yan Suveyzdis; Ravi S Bojja; Nils Metzler-Nolte; Klaus Gerwert
Label-free screening of drug-protein interactions by time-resolved Fourier transform infrared spectroscopic assays exemplified by Ras interactions.
Applied spectroscopy 2010;64(9):967-72.
2010: Nina Hüsken; Magdalena Gebala; Wolfgang Schuhmann; Nils Metzler-Nolte
A single-electrode, dual-potential ferrocene-PNA biosensor for the detection of DNA.
Chembiochem : a European journal of chemical biology 2010;11(12):1754-61.
2010: Malay Patra; Gilles Gasser; Dmytro Bobukhov; Klaus Merz; Alexander V Shtemenko; Nils Metzler-Nolte
Sequential insertion of three different organometallics into a versatile building block containing a PNA backbone.
Dalton transactions (Cambridge, England : 2003) 2010;39(24):5617-9.
2010: Konrad Meister; Johanna Niesel; Ulrich Schatzschneider; Nils Metzler-Nolte; Diedrich A Schmidt; Martina Havenith
Label-free imaging of metal-carbonyl complexes in live cells by Raman microspectroscopy.
Angewandte Chemie (International ed. in English) 2010;49(19):3310-2.
2009: Julia E Bandow; Nils Metzler-Nolte
New ways of killing the beast: prospects for inorganic-organic hybrid nanomaterials as antibacterial agents.
Chembiochem : a European journal of chemical biology 2009;10(18):2847-50.
2009: Anna M Sosniak; Gilles Gasser; Nils Metzler-Nolte
Thermal melting studies of alkyne- and ferrocene-containing PNA bioconjugates.
Organic & biomolecular chemistry 2009;7(23):4992-5000.
2009: Malay Patra; Gilles Gasser; Antonio Pinto; Klaus Merz; Ingo Ott; Julia E Bandow; Nils Metzler-Nolte
Synthesis and biological evaluation of chromium bioorganometallics based on the antibiotic platensimycin lead structure.
ChemMedChem 2009;4(11):1930-8.
2009: Rolf Chelmowski; Daniel Käfer; Stephan David Köster; Tim Klasen; Tobias Winkler; Andreas Terfort; Nils Metzler-Nolte; Christof Wöll
Postformation Modification of SAMs: using click chemistry to functionalize organic surfaces.
Langmuir : the ACS journal of surfaces and colloids 2009;25(19):11480-5.
2009: Jessica Lemke; Antonio Pinto; Philip Niehoff; Vera Vasylyeva; Nils Metzler-Nolte
Synthesis, structural characterisation and anti-proliferative activity of NHC gold amino acid and peptide conjugates.
Dalton transactions (Cambridge, England : 2003) 2009;(35):7063-70.
2009: Antonio Pinto; Ulrich Hoffmanns; Melanie Ott; Gert Fricker; Nils Metzler-Nolte
Modification with organometallic compounds improves crossing of the blood-brain barrier of [Leu5]-enkephalin derivatives in an in vitro model system.
Chembiochem : a European journal of chemical biology 2009;10(11):1852-60.
2009: Gilles Gasser; Oliver Brosch; Alexandra Ewers; Thomas Weyhermüller; Nils Metzler-Nolte
Synthesis and characterisation of hetero-bimetallic organometallic phenylalanine and PNA monomer derivatives.
Dalton transactions (Cambridge, England : 2003) 2009;(22):4310-7.
2009: Annegret Hille; Ingo Ott; Ana Kitanovic; Igor Kitanovic; Hamed Alborzinia; Elke Lederer; Stefan Wölfl; Nils Metzler-Nolte; Sven Schäfer; William S Sheldrick; Caroline Bischof; Ulrich Schatzschneider; Ronald Gust
[N,N'-Bis(salicylidene)-1,2-phenylenediamine]metal complexes with cell death promoting properties.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2009;14(5):711-25.
2009: Gilles Gasser; Merja A Neukamm; Alexandra Ewers; Oliver Brosch; Thomas Weyhermüller; Nils Metzler-Nolte
Synthesis and characterization of dicobalthexacarbonyl-alkyne derivatives of amino acids, peptides, and peptide nucleic acid (PNA) monomers.
Inorganic chemistry 2009;48(7):3157-66.
2009: Fozia Noor; Ralf Kinscherf; Gabriel A Bonaterra; Steffen Walczak; Stefan Wölfl; Nils Metzler-Nolte
Enhanced cellular uptake and cytotoxicity studies of organometallic bioconjugates of the NLS peptide in Hep G2 cells.
Chembiochem : a European journal of chemical biology 2009;10(3):493-502.
2008: Rolf Chelmowski; Stephan David Köster; Andreas Kerstan; Andreas Prekelt; Christian Grunwald; Tobias Winkler; Nils Metzler-Nolte; Andreas Terfort; Christof Wöll
Peptide-based SAMs that resist the adsorption of proteins.
Journal of the American Chemical Society 2008;130(45):14952-3.
2008: Gilles Gasser; Nina Hüsken; S David Köster; Nils Metzler-Nolte
Synthesis of organometallic PNA oligomers by click chemistry.
Chemical communications (Cambridge, England) 2008;(31):3675-7.
2008: Merja A Neukamm; Antonio Pinto; Nils Metzler-Nolte
Synthesis and cytotoxicity of a cobaltcarbonyl-alkyne enkephalin bioconjugate.
Chemical communications (Cambridge, England) 2008;(2):232-4.
2008: Srecko I Kirin; Ingo Ott; Ronald Gust; Walter Mier; Thomas Weyhermüller; Nils Metzler-Nolte
Cellular uptake quantification of metalated peptide and peptide nucleic acid bioconjugates by atomic absorption spectroscopy.
Angewandte Chemie (International ed. in English) 2008;47(5):955-9.
2007: Matthew C Kuchta; Annika Gross; Antonio Pinto; Nils Metzler-Nolte
Labeling of the neuropeptide enkephalin with functionalized tris(pyrazolyl)borate complexes: solid-phase synthesis and characterization of p-[Enk-OH]COC6H4TpPtMe3 and p-[Enk-OH]COC6H4TpMeRe(CO)3.
Inorganic chemistry 2007;46(22):9400-4.
2007: Xavier de Hatten; Zoe Cournia; Ivan Huc; Jeremy Smith; Nils Metzler-Nolte
Force-field development and molecular dynamics simulations of ferrocene-peptide conjugates as a scaffold for hydrogenase mimics.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(29):8139-52.
2007: Stephanie Pfander; Roberto Fiammengo; Srecko I Kirin; Nils Metzler-Nolte; Andres Jäschke
Reversible site-specific tagging of enzymatically synthesized RNAs using aldehyde-hydrazine chemistry and protease-cleavable linkers.
Nucleic acids research 2007;35(4):e25.
2006: Janine T Chantson; Maria Vittoria Verga Falzacappa; Sergio Crovella; Nils Metzler-Nolte
Solid-phase synthesis, characterization, and antibacterial activities of metallocene-peptide bioconjugates.
ChemMedChem 2006;1(11):1268-74.
2006: Ramin Hamzavi; Christoph Meyer; Nils Metzler-Nolte
Synthesis of a C-linked glycosylated thymine-based PNA monomer and its incorporation into a PNA oligomer.
Organic & biomolecular chemistry 2006;4(19):3648-51.
2006: Lidija Barisić; Mojca Cakić; Khaled A Mahmoud; You-nian Liu; Heinz-Bernhard Kraatz; Hans Pritzkow; Srecko I Kirin; Nils Metzler-Nolte; Vladimir Rapić
Helically chiral ferrocene peptides containing 1'-aminoferrocene-1-carboxylic acid subunits as turn inducers.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(19):4965-80.
2006: Tim Kersebohm; Srecko I Kirin; Nils Metzler-Nolte
Insertion of an internal dipeptide into PNA oligomers: thermal melting studies and further functionalization.
Bioorganic & medicinal chemistry letters 2006;16(11):2964-8.
2006: Srecko I Kirin; Heinz-Bernhard Kraatz; Nils Metzler-Nolte
Systematizing structural motifs and nomenclature in 1,n'-disubstituted ferrocene peptides.
Chemical Society reviews 2006;35(4):348-54.
2006: Ulrich Schatzschneider; Nils Metzler-Nolte
New principles in medicinal organometallic chemistry.
Angewandte Chemie (International ed. in English) 2006;45(10):1504-7.
2006: Ulrich Hoffmanns; Nils Metzler-Nolte
Use of the Sonogashira coupling reaction for the "two-step" labeling of phenylalanine peptide side chains with organometallic compounds.
Bioconjugate chemistry 2006;17(1):204-13.
2005: Srecko I Kirin; Pierre Dübon; Thomas Weyhermüller; Eckhard Bill; Nils Metzler-Nolte
Amino acid and peptide bioconjugates of copper(II) and zinc(II) complexes with a modified N,N-bis(2-picolyl)amine ligand.
Inorganic chemistry 2005;44(15):5405-15.
2005: Fozia Noor; Annette Wüstholz; Ralf Kinscherf; Nils Metzler-Nolte
A cobaltocenium-peptide bioconjugate shows enhanced cellular uptake and directed nuclear delivery.
Angewandte Chemie (International ed. in English) 2005;44(16):2429-32.
2004: Dave R van Staveren; Nils Metzler-Nolte
Bioorganometallic chemistry of ferrocene.
Chemical reviews 2004;104(12):5931-85.
2004: Dave R van Staveren; Stefan Mundwiler; Ulrich Hoffmanns; Jae Kyoung Pak; Bernhard Spingler; Nils Metzler-Nolte; Roger Alberto
Conjugation of a novel histidine derivative to biomolecules and labelling with [99mTc(OH2)3(CO)3]+.
Organic & biomolecular chemistry 2004;2(18):2593-603.
2004: Lidija Barisić; Maja Dropucić; Vladimir Rapić; Hans Pritzkow; Srecko I Kirin; Nils Metzler-Nolte
The first oligopeptide derivative of 1'-aminoferrocene-1-carboxylic acid shows helical chirality with antiparallel strands.
Chemical communications (Cambridge, England) 2004;(17):2004-5.
2004: Srecko I Kirin; Christoph M Happel; Silvia Hrubanova; Thomas Weyhermuller; Christoph Klein; Nils Metzler-Nolte
Synthesis, structure and comparison of the DNA cleavage ability of metal complexes M(II)L with the N-(2-ethoxyethanol)-bis(2-picolyl)amine ligand L (M = Co, Ni, Cu and Zn).
Dalton transactions (Cambridge, England : 2003) 2004;(8):1201-7.
2002: Dave R van Staveren; Nils Metzler-Nolte
Labelling of [Leu5]-enkephalin with organometallic Mo complexes by solid-phase synthesis.
Chemical communications (Cambridge, England) 2002;(13):1406-7.
2002: Dave R van Staveren; Eckhard Bill; Eberhard Bothe; Michael Bühl; Thomas Weyhermüller; Nils Metzler-Nolte
Fluxional processes in diamagnetic and paramagnetic allyl dicarbonyl and 2-methylallyl dicarbonyl molybdenum histidinato complexes as revealed by spectroscopic data and density functional calculations.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(7):1649-62.
2000: A Hess; J Sehnert; Thomas Weyhermüller; Nils Metzler-Nolte
Chiral ferrocene amines derived from amino acids and peptides: synthesis, solution and X-ray crystal structures and electrochemical investigations.
Inorganic chemistry 2000;39(24):5437-43.