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Matthew Meyerson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Anatomy

Tumor Cell Line

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Living Beings

Mice

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Oligonucleotide Array Sequence Analysis

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Publications

TOP 3
Bass Adam J; Meyerson Matthew
Genome-wide association study in esophageal squamous cell carcinoma.
Wagner Patrick L; Perner Sven; Rickman David S; LaFargue Christopher J; Kitabayashi Naoki; Johnstone Stephen F; Weir Barbara A; Meyerson Matthew; Altorki Nasser K; Rubin Mark A
In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma.
Viswanathan Srinivas R; Powers John T; Einhorn William; Hoshida Yujin; Ng Tony L; Toffanin Sara; O'Sullivan Maureen; Lu Jun; Phillips Letha A; Lockhart Victoria L; Shah Samar P; Tanwar Pradeep S; Mermel Craig H; Beroukhim Rameen; Azam Mohammad; Teixeira Jose; Meyerson Matthew; Hughes Timothy P; Llovet Josep M; Radich Jerald; Mullighan Charles G; Golub Todd R; Sorensen Poul H; Daley George Q
Lin28 promotes transformation and is associated with advanced human malignancies.

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All Publications

2009: Bass Adam J; Meyerson Matthew
Genome-wide association study in esophageal squamous cell carcinoma.
Gastroenterology 2009;137(5):1573-6.
2009: Wagner Patrick L; Perner Sven; Rickman David S; LaFargue Christopher J; Kitabayashi Naoki; Johnstone Stephen F; Weir Barbara A; Meyerson Matthew; Altorki Nasser K; Rubin Mark A
In situ evidence of KRAS amplification and association with increased p21 levels in non-small cell lung carcinoma.
American journal of clinical pathology 2009;132(4):500-5.
2009: Viswanathan Srinivas R; Powers John T; Einhorn William; Hoshida Yujin; Ng Tony L; Toffanin Sara; O'Sullivan Maureen; Lu Jun; Phillips Letha A; Lockhart Victoria L; Shah Samar P; Tanwar Pradeep S; Mermel Craig H; Beroukhim Rameen; Azam Mohammad; Teixeira Jose; Meyerson Matthew; Hughes Timothy P; Llovet Josep M; Radich Jerald; Mullighan Charles G; Golub Todd R; Sorensen Poul H; Daley George Q
Lin28 promotes transformation and is associated with advanced human malignancies.
Nature genetics 2009;41(7):843-8.
2009: Beroukhim Rameen; Brunet Jean-Philippe; Di Napoli Arianna; Mertz Kirsten D; Seeley Apryle; Pires Maira M; Linhart David; Worrell Robert A; Moch Holger; Rubin Mark A; Sellers William R; Meyerson Matthew; Linehan W Marston; Kaelin William G; Signoretti Sabina
Patterns of gene expression and copy-number alterations in von-hippel lindau disease-associated and sporadic clear cell carcinoma of the kidney.
Cancer research 2009;69(11):4674-81.
2009: Sos Martin L; Michel Kathrin; Zander Thomas; Weiss Jonathan; Frommolt Peter; Peifer Martin; Li Danan; Ullrich Roland; Koker Mirjam; Fischer Florian; Shimamura Takeshi; Rauh Daniel; Mermel Craig; Fischer Stefanie; Stückrath Isabel; Heynck Stefanie; Beroukhim Rameen; Lin William; Winckler Wendy; Shah Kinjal; LaFramboise Thomas; Moriarty Whei F; Hanna Megan; Tolosi Laura; Rahnenführer Jörg; Verhaak Roel; Chiang Derek; Getz Gad; Hellmich Martin; Wolf Jürgen; Girard Luc; Peyton Michael; Weir Barbara A; Chen Tzu-Hsiu; Greulich Heidi; Barretina Jordi; Shapiro Geoffrey I; Garraway Levi A; Gazdar Adi F; Minna John D; Meyerson Matthew; Wong Kwok-Kin; Thomas Roman K
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions.
The Journal of clinical investigation 2009;119(6):1727-40.
2009: Sos Martin L; Koker Mirjam; Weir Barbara A; Heynck Stefanie; Rabinovsky Rosalia; Zander Thomas; Seeger Jens M; Weiss Jonathan; Fischer Florian; Frommolt Peter; Michel Kathrin; Peifer Martin; Mermel Craig; Girard Luc; Peyton Michael; Gazdar Adi F; Minna John D; Garraway Levi A; Kashkar Hamid; Pao William; Meyerson Matthew; Thomas Roman K
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR.
Cancer research 2009;69(8):3256-61.
2009: Demichelis Francesca; Setlur Sunita R; Beroukhim Rameen; Perner Sven; Korbel Jan O; Lafargue Christopher J; Pflueger Dorothee; Pina Cara; Hofer Matthias D; Sboner Andrea; Svensson Maria A; Rickman David S; Urban Alex; Snyder Michael; Meyerson Matthew; Lee Charles; Gerstein Mark B; Kuefer Rainer; Rubin Mark A
Distinct genomic aberrations associated with ERG rearranged prostate cancer.
Genes, chromosomes & cancer 2009;48(4):366-80.
2009: Salvesen H B; Carter S L; Mannelqvist M; Dutt A; Getz G; Stefansson I M; Raeder M B; Sos M L; Engelsen I B; Trovik J; Wik E; Greulich H; Bø T H; Jonassen I; Thomas R K; Zander T; Garraway L A; Oyan A M; Sellers W R; Kalland K H; Meyerson M; Akslen L A; Beroukhim R
Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(12):4834-9.
2009: Etemadmoghadam Dariush; deFazio Anna; Beroukhim Rameen; Mermel Craig; George Joshy; Getz Gad; Tothill Richard; Okamoto Aikou; Raeder Maria B; Harnett Paul; Lade Stephen; Akslen Lars A; Tinker Anna V; Locandro Bianca; Alsop Kathryn; Chiew Yoke-Eng; Traficante Nadia; Fereday Sian; Johnson Daryl; Fox Stephen; Sellers William; Urashima Mitsuyoshi; Salvesen Helga B; Meyerson Matthew; Bowtell David;
Integrated genome-wide DNA copy number and expression analysis identifies distinct mechanisms of primary chemoresistance in ovarian carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1417-27.
2009: Rozenblatt-Rosen Orit; Nagaike Takashi; Francis Joshua M; Kaneko Syuzo; Glatt Karen A; Hughes Christina M; LaFramboise Thomas; Manley James L; Meyerson Matthew
The tumor suppressor Cdc73 functionally associates with CPSF and CstF 3' mRNA processing factors.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(3):755-60.
2009: Perera Samanthi A; Li Danan; Shimamura Takeshi; Raso Maria G; Ji Hongbin; Chen Liang; Borgman Christa L; Zaghlul Sara; Brandstetter Kathleyn A; Kubo Shigeto; Takahashi Masaya; Chirieac Lucian R; Padera Robert F; Bronson Roderick T; Shapiro Geoffrey I; Greulich Heidi; Meyerson Matthew; Guertler Ulrich; Chesa Pilar Garin; Solca Flavio; Wistuba Ignacio I; Wong Kwok-Kin
HER2YVMA drives rapid development of adenosquamous lung tumors in mice that are sensitive to BIBW2992 and rapamycin combination therapy.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(2):474-9.
2009: Chiang Derek Y; Getz Gad; Jaffe David B; O'Kelly Michael J T; Zhao Xiaojun; Carter Scott L; Russ Carsten; Nusbaum Chad; Meyerson Matthew; Lander Eric S
High-resolution mapping of copy-number alterations with massively parallel sequencing.
Nature methods 2009;6(1):99-103.
2009: Perner S; Wagner P L; Soltermann A; LaFargue C; Tischler V; Weir B A; Weder W; Meyerson M; Giordano T J; Moch H; Rubin M A
TTF1 expression in non-small cell lung carcinoma: association with TTF1 gene amplification and improved survival.
The Journal of pathology 2009;217(1):65-72.
2008: Luo Biao; Cheung Hiu Wing; Subramanian Aravind; Sharifnia Tanaz; Okamoto Michael; Yang Xiaoping; Hinkle Greg; Boehm Jesse S; Beroukhim Rameen; Weir Barbara A; Mermel Craig; Barbie David A; Awad Tarif; Zhou Xiaochuan; Nguyen Tuyen; Piqani Bruno; Li Cheng; Golub Todd R; Meyerson Matthew; Hacohen Nir; Hahn William C; Lander Eric S; Sabatini David M; Root David E
Highly parallel identification of essential genes in cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(51):20380-5.
2008: Villanueva Augusto; Chiang Derek Y; Newell Pippa; Peix Judit; Thung Swan; Alsinet Clara; Tovar Victoria; Roayaie Sasan; Minguez Beatriz; Sole Manel; Battiston Carlo; Van Laarhoven Stijn; Fiel Maria I; Di Feo Analisa; Hoshida Yujin; Yea Steven; Toffanin Sara; Ramos Alex; Martignetti John A; Mazzaferro Vincenzo; Bruix Jordi; Waxman Samuel; Schwartz Myron; Meyerson Matthew; Friedman Scott L; Llovet Josep M
Pivotal role of mTOR signaling in hepatocellular carcinoma.
Gastroenterology 2008;135(6):1972-83, 1983.e1-11.
2008: Wistuba Ignacio I; Meyerson Matthew
Chromosomal deletions and progression of premalignant lesions: less is more.
Cancer prevention research (Philadelphia, Pa.) 2008;1(6):404-8.
2008: Ding Li; Getz Gad; Wheeler David A; Mardis Elaine R; McLellan Michael D; Cibulskis Kristian; Sougnez Carrie; Greulich Heidi; Muzny Donna M; Morgan Margaret B; Fulton Lucinda; Fulton Robert S; Zhang Qunyuan; Wendl Michael C; Lawrence Michael S; Larson David E; Chen Ken; Dooling David J; Sabo Aniko; Hawes Alicia C; Shen Hua; Jhangiani Shalini N; Lewis Lora R; Hall Otis; Zhu Yiming; Mathew Tittu; Ren Yanru; Yao Jiqiang; Scherer Steven E; Clerc Kerstin; Metcalf Ginger A; Ng Brian; Milosavljevic Aleksandar; Gonzalez-Garay Manuel L; Osborne John R; Meyer Rick; Shi Xiaoqi; Tang Yuzhu; Koboldt Daniel C; Lin Ling; Abbott Rachel; Miner Tracie L; Pohl Craig; Fewell Ginger; Haipek Carrie; Schmidt Heather; Dunford-Shore Brian H; Kraja Aldi; Crosby Seth D; Sawyer Christopher S; Vickery Tammi; Sander Sacha; Robinson Jody; Winckler Wendy; Baldwin Jennifer; Chirieac Lucian R; Dutt Amit; Fennell Tim; Hanna Megan; Johnson Bruce E; Onofrio Robert C; Thomas Roman K; Tonon Giovanni; Weir Barbara A; Zhao Xiaojun; Ziaugra Liuda; Zody Michael C; Giordano Thomas; Orringer Mark B; Roth Jack A; Spitz Margaret R; Wistuba Ignacio I; Ozenberger Bradley; Good Peter J; Chang Andrew C; Beer David G; Watson Mark A; Ladanyi Marc; Broderick Stephen; Yoshizawa Akihiko; Travis William D; Pao William; Province Michael A; Weinstock George M; Varmus Harold E; Gabriel Stacey B; Lander Eric S; Gibbs Richard A; Meyerson Matthew; Wilson Richard K
Somatic mutations affect key pathways in lung adenocarcinoma.
Nature 2008;455(7216):1069-75.
2008: George Rani E; Sanda Takaomi; Hanna Megan; Fröhling Stefan; Luther William; Zhang Jianming; Ahn Yebin; Zhou Wenjun; London Wendy B; McGrady Patrick; Xue Liquan; Zozulya Sergey; Gregor Vlad E; Webb Thomas R; Gray Nathanael S; Gilliland D Gary; Diller Lisa; Greulich Heidi; Morris Stephan W; Meyerson Matthew; Look A Thomas
Activating mutations in ALK provide a therapeutic target in neuroblastoma.
Nature 2008;455(7215):975-8.
2008: Firestein Ron; Bass Adam J; Kim So Young; Dunn Ian F; Silver Serena J; Guney Isil; Freed Ellen; Ligon Azra H; Vena Natalie; Ogino Shuji; Chheda Milan G; Tamayo Pablo; Finn Stephen; Shrestha Yashaswi; Boehm Jesse S; Jain Supriya; Bojarski Emeric; Mermel Craig; Barretina Jordi; Chan Jennifer A; Baselga Jose; Tabernero Josep; Root David E; Fuchs Charles S; Loda Massimo; Shivdasani Ramesh A; Meyerson Matthew; Hahn William C
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity.
Nature 2008;455(7212):547-51.
2008: Chiang Derek Y; Villanueva Augusto; Hoshida Yujin; Peix Judit; Newell Philippa; Minguez Beatriz; LeBlanc Amanda C; Donovan Diana J; Thung Swan N; Solé Manel; Tovar Victoria; Alsinet Clara; Ramos Alex H; Barretina Jordi; Roayaie Sasan; Schwartz Myron; Waxman Samuel; Bruix Jordi; Mazzaferro Vincenzo; Ligon Azra H; Najfeld Vesna; Friedman Scott L; Sellers William R; Meyerson Matthew; Llovet Josep M
Focal gains of VEGFA and molecular classification of hepatocellular carcinoma.
Cancer research 2008;68(16):6779-88.
2008: Shedden Kerby; Taylor Jeremy M G; Enkemann Steven A; Tsao Ming-Sound; Yeatman Timothy J; Gerald William L; Eschrich Steven; Jurisica Igor; Giordano Thomas J; Misek David E; Chang Andrew C; Zhu Chang Qi; Strumpf Daniel; Hanash Samir; Shepherd Frances A; Ding Keyue; Seymour Lesley; Naoki Katsuhiko; Pennell Nathan; Weir Barbara; Verhaak Roel; Ladd-Acosta Christine; Golub Todd; Gruidl Michael; Sharma Anupama; Szoke Janos; Zakowski Maureen; Rusch Valerie; Kris Mark; Viale Agnes; Motoi Noriko; Travis William; Conley Barbara; Seshan Venkatraman E; Meyerson Matthew; Kuick Rork; Dobbin Kevin K; Lively Tracy; Jacobson James W; Beer David G
Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study.
Nature medicine 2008;14(8):822-7.
2008: Li D; Ambrogio L; Shimamura T; Kubo S; Takahashi M; Chirieac L R; Padera R F; Shapiro G I; Baum A; Himmelsbach F; Rettig W J; Meyerson M; Solca F; Greulich H; Wong K-K
BIBW2992, an irreversible EGFR/HER2 inhibitor highly effective in preclinical lung cancer models.
Oncogene 2008;27(34):4702-11.
2008: Shimamura Takeshi; Li Danan; Ji Hongbin; Haringsma Henry J; Liniker Elizabeth; Borgman Christa L; Lowell April M; Minami Yuko; McNamara Kate; Perera Samanthi A; Zaghlul Sara; Thomas Roman K; Greulich Heidi; Kobayashi Susumu; Chirieac Lucian R; Padera Robert F; Kubo Shigeto; Takahashi Masaya; Tenen Daniel G; Meyerson Matthew; Wong Kwok-Kin; Shapiro Geoffrey I
Hsp90 inhibition suppresses mutant EGFR-T790M signaling and overcomes kinase inhibitor resistance.
Cancer research 2008;68(14):5827-38.
2008: Koivunen J P; Kim J; Lee J; Rogers A M; Park J O; Zhao X; Naoki K; Okamoto I; Nakagawa K; Yeap B Y; Meyerson M; Wong K-K; Richards W G; Sugarbaker D J; Johnson B E; Jänne P A
Mutations in the LKB1 tumour suppressor are frequently detected in tumours from Caucasian but not Asian lung cancer patients.
British journal of cancer 2008;99(2):245-52.
2008: Koivunen Jussi P; Mermel Craig; Zejnullahu Kreshnik; Murphy Carly; Lifshits Eugene; Holmes Alison J; Choi Hwan Geun; Kim Jhingook; Chiang Derek; Thomas Roman; Lee Jinseon; Richards William G; Sugarbaker David J; Ducko Christopher; Lindeman Neal; Marcoux J Paul; Engelman Jeffrey A; Gray Nathanael S; Lee Charles; Meyerson Matthew; Jänne Pasi A
EML4-ALK fusion gene and efficacy of an ALK kinase inhibitor in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(13):4275-83.
2008: Dutt Amit; Salvesen Helga B; Chen Tzu-Hsiu; Ramos Alex H; Onofrio Robert C; Hatton Charlie; Nicoletti Richard; Winckler Wendy; Grewal Rupinder; Hanna Megan; Wyhs Nicolas; Ziaugra Liuda; Richter Daniel J; Trovik Jone; Engelsen Ingeborg B; Stefansson Ingunn M; Fennell Tim; Cibulskis Kristian; Zody Michael C; Akslen Lars A; Gabriel Stacey; Wong Kwok-Kin; Sellers William R; Meyerson Matthew; Greulich Heidi
Drug-sensitive FGFR2 mutations in endometrial carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(25):8713-7.
2008: Loriaux Marc M; Levine Ross L; Tyner Jeffrey W; Fröhling Stefan; Scholl Claudia; Stoffregen Eric P; Wernig Gerlinde; Erickson Heidi; Eide Christopher A; Berger Roland; Bernard Olivier A; Griffin James D; Stone Richard M; Lee Benjamin; Meyerson Matthew; Heinrich Michael C; Deininger Michael W; Gilliland D Gary; Druker Brian J
High-throughput sequence analysis of the tyrosine kinome in acute myeloid leukemia.
Blood 2008;111(9):4788-96.
2008: MacConaill Laura; Meyerson Matthew
Adding pathogens by genomic subtraction.
Nature genetics 2008;40(4):380-2.
2008: Schlisio Susanne; Kenchappa Rajappa S; Vredeveld Liesbeth C W; George Rani E; Stewart Rodney; Greulich Heidi; Shahriari Kristina; Nguyen Nguyen V; Pigny Pascal; Dahia Patricia L; Pomeroy Scott L; Maris John M; Look A Thomas; Meyerson Matthew; Peeper Daniel S; Carter Bruce D; Kaelin William G
The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Genes & development 2008;22(7):884-93.
2008: Swanson Kenneth D; Winter Jordan M; Reis Marcelo; Bentires-Alj Mohamed; Greulich Heidi; Grewal Rupinder; Hruban Ralph H; Yeo Charles J; Yassin Yosuf; Iartchouk Oleg; Montgomery Kate; Whitman Susan P; Caligiuri Michael A; Loh Mignon L; Gilliland D Gary; Look A Thomas; Kucherlapati Raju; Kern Scott E; Meyerson Matthew; Neel Benjamin G
SOS1 mutations are rare in human malignancies: implications for Noonan Syndrome patients.
Genes, chromosomes & cancer 2008;47(3):253-9.
2008: Lin William M; Baker Alissa C; Beroukhim Rameen; Winckler Wendy; Feng Whei; Marmion Jennifer M; Laine Elisabeth; Greulich Heidi; Tseng Hsiuyi; Gates Casey; Hodi F Stephen; Dranoff Glenn; Sellers William R; Thomas Roman K; Meyerson Matthew; Golub Todd R; Dummer Reinhard; Herlyn Meenhard; Getz Gad; Garraway Levi A
Modeling genomic diversity and tumor dependency in malignant melanoma.
Cancer research 2008;68(3):664-73.
2008: Yun Cai-Hong; Mengwasser Kristen E; Toms Angela V; Woo Michele S; Greulich Heidi; Wong Kwok-Kin; Meyerson Matthew; Eck Michael J
The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(6):2070-5.
2008: Engelsen Ingeborg B; Stefansson Ingunn M; Beroukhim Rameen; Sellers William R; Meyerson Matthew; Akslen Lars A; Salvesen Helga B
HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas.
International journal of oncology 2008;32(2):307-16.
2008: Taylor Barry S; Barretina Jordi; Socci Nicholas D; Decarolis Penelope; Ladanyi Marc; Meyerson Matthew; Singer Samuel; Sander Chris
Functional copy-number alterations in cancer.
PloS one 2008;3(9):e3179.
2008: Li Cheng; Beroukhim Rameen; Weir Barbara A; Winckler Wendy; Garraway Levi A; Sellers William R; Meyerson Matthew
Major copy proportion analysis of tumor samples using SNP arrays.
BMC bioinformatics 2008;9():204.
2007: Engelman Jeffrey A; Zejnullahu Kreshnik; Gale Christopher-Michael; Lifshits Eugene; Gonzales Andrea J; Shimamura Takeshi; Zhao Feng; Vincent Patrick W; Naumov George N; Bradner James E; Althaus Irene W; Gandhi Leena; Shapiro Geoffrey I; Nelson James M; Heymach John V; Meyerson Matthew; Wong Kwok-Kin; Jänne Pasi A
PF00299804, an irreversible pan-ERBB inhibitor, is effective in lung cancer models with EGFR and ERBB2 mutations that are resistant to gefitinib.
Cancer research 2007;67(24):11924-32.
2007: Beroukhim Rameen; Getz Gad; Nghiemphu Leia; Barretina Jordi; Hsueh Teli; Linhart David; Vivanco Igor; Lee Jeffrey C; Huang Julie H; Alexander Sethu; Du Jinyan; Kau Tweeny; Thomas Roman K; Shah Kinjal; Soto Horacio; Perner Sven; Prensner John; Debiasi Ralph M; Demichelis Francesca; Hatton Charlie; Rubin Mark A; Garraway Levi A; Nelson Stan F; Liau Linda; Mischel Paul S; Cloughesy Tim F; Meyerson Matthew; Golub Todd A; Lander Eric S; Mellinghoff Ingo K; Sellers William R
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):20007-12.
2007: Weir Barbara A; Woo Michele S; Getz Gad; Perner Sven; Ding Li; Beroukhim Rameen; Lin William M; Province Michael A; Kraja Aldi; Johnson Laura A; Shah Kinjal; Sato Mitsuo; Thomas Roman K; Barletta Justine A; Borecki Ingrid B; Broderick Stephen; Chang Andrew C; Chiang Derek Y; Chirieac Lucian R; Cho Jeonghee; Fujii Yoshitaka; Gazdar Adi F; Giordano Thomas; Greulich Heidi; Hanna Megan; Johnson Bruce E; Kris Mark G; Lash Alex; Lin Ling; Lindeman Neal; Mardis Elaine R; McPherson John D; Minna John D; Morgan Margaret B; Nadel Mark; Orringer Mark B; Osborne John R; Ozenberger Brad; Ramos Alex H; Robinson James; Roth Jack A; Rusch Valerie; Sasaki Hidefumi; Shepherd Frances; Sougnez Carrie; Spitz Margaret R; Tsao Ming-Sound; Twomey David; Verhaak Roel G W; Weinstock George M; Wheeler David A; Winckler Wendy; Yoshizawa Akihiko; Yu Soyoung; Zakowski Maureen F; Zhang Qunyuan; Beer David G; Wistuba Ignacio I; Watson Mark A; Garraway Levi A; Ladanyi Marc; Travis William D; Pao William; Rubin Mark A; Gabriel Stacey B; Gibbs Richard A; Varmus Harold E; Wilson Richard K; Lander Eric S; Meyerson Matthew
Characterizing the cancer genome in lung adenocarcinoma.
Nature 2007;450(7171):893-8.
2007: Getz Gad; Höfling Holger; Mesirov Jill P; Golub Todd R; Meyerson Matthew; Tibshirani Robert; Lander Eric S
Comment on "The consensus coding sequences of human breast and colorectal cancers".
Science (New York, N.Y.) 2007;317(5844):1500.
2007: Ji Hongbin; Ramsey Matthew R; Hayes D Neil; Fan Cheng; McNamara Kate; Kozlowski Piotr; Torrice Chad; Wu Michael C; Shimamura Takeshi; Perera Samanthi A; Liang Mei-Chih; Cai Dongpo; Naumov George N; Bao Lei; Contreras Cristina M; Li Danan; Chen Liang; Krishnamurthy Janakiraman; Koivunen Jussi; Chirieac Lucian R; Padera Robert F; Bronson Roderick T; Lindeman Neal I; Christiani David C; Lin Xihong; Shapiro Geoffrey I; Jänne Pasi A; Johnson Bruce E; Meyerson Matthew; Kwiatkowski David J; Castrillon Diego H; Bardeesy Nabeel; Sharpless Norman E; Wong Kwok-Kin
LKB1 modulates lung cancer differentiation and metastasis.
Nature 2007;448(7155):807-10.
2007: Meyerson Matthew
Cancer: broken genes in solid tumours.
Nature 2007;448(7153):545-6.
2007: Kaneko Syuzo; Rozenblatt-Rosen Orit; Meyerson Matthew; Manley James L
The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription termination.
Genes & development 2007;21(14):1779-89.
2007: Li Danan; Shimamura Takeshi; Ji Hongbin; Chen Liang; Haringsma Henry J; McNamara Kate; Liang Mei-Chih; Perera Samanthi A; Zaghlul Sara; Borgman Christa L; Kubo Shigeto; Takahashi Masaya; Sun Yanping; Chirieac Lucian R; Padera Robert F; Lindeman Neal I; Jänne Pasi A; Thomas Roman K; Meyerson Matthew L; Eck Michael J; Engelman Jeffrey A; Shapiro Geoffrey I; Wong Kwok-Kin
Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy.
Cancer cell 2007;12(1):81-93.
2007: Minami Y; Shimamura T; Shah K; LaFramboise T; Glatt K A; Liniker E; Borgman C L; Haringsma H J; Feng W; Weir B A; Lowell A M; Lee J C; Wolf J; Shapiro G I; Wong K-K; Meyerson M; Thomas R K
The major lung cancer-derived mutants of ERBB2 are oncogenic and are associated with sensitivity to the irreversible EGFR/ERBB2 inhibitor HKI-272.
Oncogene 2007;26(34):5023-7.
2007: Boehm Jesse S; Zhao Jean J; Yao Jun; Kim So Young; Firestein Ron; Dunn Ian F; Sjostrom Sarah K; Garraway Levi A; Weremowicz Stanislawa; Richardson Andrea L; Greulich Heidi; Stewart Carly J; Mulvey Laura A; Shen Rhine R; Ambrogio Lauren; Hirozane-Kishikawa Tomoko; Hill David E; Vidal Marc; Meyerson Matthew; Grenier Jennifer K; Hinkle Greg; Root David E; Roberts Thomas M; Lander Eric S; Polyak Kornelia; Hahn William C
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Cell 2007;129(6):1065-79.
2007: Yuza Yuki; Glatt Karen A; Jiang Jingrui; Greulich Heidi; Minami Yuko; Woo Michele S; Shimamura Takeshi; Shapiro Geoffrey; Lee Jeffrey C; Ji Hongbin; Feng Whei; Chen Tzu-Hsiu; Yanagisawa Haruhiko; Wong Kwok-Kin; Meyerson Matthew
Allele-dependent variation in the relative cellular potency of distinct EGFR inhibitors.
Cancer biology & therapy 2007;6(5):661-7.
2007: Yun Cai-Hong; Boggon Titus J; Li Yiqun; Woo Michele S; Greulich Heidi; Meyerson Matthew; Eck Michael J
Structures of lung cancer-derived EGFR mutants and inhibitor complexes: mechanism of activation and insights into differential inhibitor sensitivity.
Cancer cell 2007;11(3):217-27.
2007: Thomas Roman K; Baker Alissa C; Debiasi Ralph M; Winckler Wendy; Laframboise Thomas; Lin William M; Wang Meng; Feng Whei; Zander Thomas; MacConaill Laura; Lee Jeffrey C; Nicoletti Rick; Hatton Charlie; Goyette Mary; Girard Luc; Majmudar Kuntal; Ziaugra Liuda; Wong Kwok-Kin; Gabriel Stacey; Beroukhim Rameen; Peyton Michael; Barretina Jordi; Dutt Amit; Emery Caroline; Greulich Heidi; Shah Kinjal; Sasaki Hidefumi; Gazdar Adi; Minna John; Armstrong Scott A; Mellinghoff Ingo K; Hodi F Stephen; Dranoff Glenn; Mischel Paul S; Cloughesy Tim F; Nelson Stan F; Liau Linda M; Mertz Kirsten; Rubin Mark A; Moch Holger; Loda Massimo; Catalona William; Fletcher Jonathan; Signoretti Sabina; Kaye Frederic; Anderson Kenneth C; Demetri George D; Dummer Reinhard; Wagner Stephan; Herlyn Meenhard; Sellers William R; Meyerson Matthew; Garraway Levi A
High-throughput oncogene mutation profiling in human cancer.
Nature genetics 2007;39(3):347-51.
2007: Jackman David M; Yeap Beow Y; Lindeman Neal I; Fidias Panos; Rabin Michael S; Temel Jennifer; Skarin Arthur T; Meyerson Matthew; Holmes Alison J; Borras Ana M; Freidlin Boris; Ostler Patricia A; Lucca Joan; Lynch Thomas J; Johnson Bruce E; Jänne Pasi A
Phase II clinical trial of chemotherapy-naive patients > or = 70 years of age treated with erlotinib for advanced non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(7):760-6.
2007: Sequist Lecia V; Joshi Victoria A; Jänne Pasi A; Muzikansky Alona; Fidias Panos; Meyerson Matthew; Haber Daniel A; Kucherlapati Raju; Johnson Bruce E; Lynch Thomas J
Response to treatment and survival of patients with non-small cell lung cancer undergoing somatic EGFR mutation testing.
The oncologist 2007;12(1):90-8.
2007: George Rani E; Attiyeh Edward F; Li Shuli; Moreau Lisa A; Neuberg Donna; Li Cheng; Fox Edward A; Meyerson Matthew; Diller Lisa; Fortina Paolo; Look A Thomas; Maris John M
Genome-wide analysis of neuroblastomas using high-density single nucleotide polymorphism arrays.
PloS one 2007;2(2):e255.
2006: Lee Jeffrey C; Vivanco Igor; Beroukhim Rameen; Huang Julie H Y; Feng Whei L; DeBiasi Ralph M; Yoshimoto Koji; King Jennifer C; Nghiemphu Phioanh; Yuza Yuki; Xu Qing; Greulich Heidi; Thomas Roman K; Paez J Guillermo; Peck Timothy C; Linhart David J; Glatt Karen A; Getz Gad; Onofrio Robert; Ziaugra Liuda; Levine Ross L; Gabriel Stacey; Kawaguchi Tomohiro; O'Neill Keith; Khan Haumith; Liau Linda M; Nelson Stanley F; Rao P Nagesh; Mischel Paul; Pieper Russell O; Cloughesy Tim; Leahy Daniel J; Sellers William R; Sawyers Charles L; Meyerson Matthew; Mellinghoff Ingo K
Epidermal growth factor receptor activation in glioblastoma through novel missense mutations in the extracellular domain.
PLoS medicine 2006;3(12):e485.
2006: Kobayashi Susumu; Shimamura Takeshi; Monti Stefano; Steidl Ulrich; Hetherington Christopher J; Lowell April M; Golub Todd; Meyerson Matthew; Tenen Daniel G; Shapiro Geoffrey I; Halmos Balázs
Transcriptional profiling identifies cyclin D1 as a critical downstream effector of mutant epidermal growth factor receptor signaling.
Cancer research 2006;66(23):11389-98.
2006: Hayes D Neil; Monti Stefano; Parmigiani Giovanni; Gilks C Blake; Naoki Katsuhiko; Bhattacharjee Arindam; Socinski Mark A; Perou Charles; Meyerson Matthew
Gene expression profiling reveals reproducible human lung adenocarcinoma subtypes in multiple independent patient cohorts.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(31):5079-90.
2006: MacConaill Laura E; Hughes Christina M; Rozenblatt-Rosen Orit; Nannepaga Suraj; Meyerson Matthew
Phosphorylation of the menin tumor suppressor protein on serine 543 and serine 583.
Molecular cancer research : MCR 2006;4(10):793-801.
2006: Perner Sven; Demichelis Francesca; Beroukhim Rameen; Schmidt Folke H; Mosquera Juan-Miguel; Setlur Sunita; Tchinda Joelle; Tomlins Scott A; Hofer Matthias D; Pienta Kenneth G; Kuefer Rainer; Vessella Robert; Sun Xiao-Wei; Meyerson Matthew; Lee Charles; Sellers William R; Chinnaiyan Arul M; Rubin Mark A
TMPRSS2:ERG fusion-associated deletions provide insight into the heterogeneity of prostate cancer.
Cancer research 2006;66(17):8337-41.
2006: Costa Daniel B; Dayaram Tajhal; D'Alo Francesco; Wouters Bas J; Tenen Daniel G; Meyerson Matthew; Tsao Ming-Sound; Halmos Balazs
C/EBP alpha mutations in lung cancer.
Lung cancer (Amsterdam, Netherlands) 2006;53(2):253-4.
2006: Sequist Lecia V; Joshi Victoria A; Jänne Pasi A; Bell Daphne W; Fidias Panos; Lindeman Neal I; Louis David N; Lee Jeffrey C; Mark Eugene J; Longtine Janina; Verlander Peter; Kucherlapati Raju; Meyerson Matthew; Haber Daniel A; Johnson Bruce E; Lynch Thomas J
Epidermal growth factor receptor mutation testing in the care of lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 2):4403s-4408s.
2006: Thomas Roman K; Weir Barbara; Meyerson Matthew
Genomic approaches to lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 2):4384s-4391s.
2006: Lynch Thomas J; Adjei Alex A; Bunn Paul A; Eisen Tim G; Engelman Jeffrey; Goss Glenwood D; Haber Daniel A; Heymach John V; Jänne Pasi A; Johnson Bruce E; Johnson David H; Lilenbaum Rogerio C; Meyerson Matthew; Sandler Alan B; Sequist Lecia V; Settleman Jeffrey; Wong Kwok-Kin; Hart Carol S
Summary statement: novel agents in the treatment of lung cancer: advances in epidermal growth factor receptor-targeted agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(14 Pt 2):4365s-4371s.
2006: Jackman David M; Yeap Beow Y; Sequist Lecia V; Lindeman Neal; Holmes Alison J; Joshi Victoria A; Bell Daphne W; Huberman Mark S; Halmos Balazs; Rabin Michael S; Haber Daniel A; Lynch Thomas J; Meyerson Matthew; Johnson Bruce E; Jänne Pasi A
Exon 19 deletion mutations of epidermal growth factor receptor are associated with prolonged survival in non-small cell lung cancer patients treated with gefitinib or erlotinib.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(13):3908-14.
2006: Shimamura Takeshi; Ji Hongbin; Minami Yuko; Thomas Roman K; Lowell April M; Shah Kinjal; Greulich Heidi; Glatt Karen A; Meyerson Matthew; Shapiro Geoffrey I; Wong Kwok-Kin
Non-small-cell lung cancer and Ba/F3 transformed cells harboring the ERBB2 G776insV_G/C mutation are sensitive to the dual-specific epidermal growth factor receptor and ERBB2 inhibitor HKI-272.
Cancer research 2006;66(13):6487-91.
2006: Thomas Roman K; Nickerson Elizabeth; Simons Jan F; Jänne Pasi A; Tengs Torstein; Yuza Yuki; Garraway Levi A; LaFramboise Thomas; Lee Jeffrey C; Shah Kinjal; O'Neill Keith; Sasaki Hidefumi; Lindeman Neal; Wong Kwok-Kin; Borras Ana M; Gutmann Edward J; Dragnev Konstantin H; DeBiasi Ralph; Chen Tzu-Hsiu; Glatt Karen A; Greulich Heidi; Desany Brian; Lubeski Christine K; Brockman William; Alvarez Pablo; Hutchison Stephen K; Leamon J H; Ronan Michael T; Turenchalk Gregory S; Egholm Michael; Sellers William R; Rothberg Jonathan M; Meyerson Matthew
Sensitive mutation detection in heterogeneous cancer specimens by massively parallel picoliter reactor sequencing.
Nature medicine 2006;12(7):852-5.
2006: Beroukhim Rameen; Lin Ming; Park Yuhyun; Hao Ke; Zhao Xiaojun; Garraway Levi A; Fox Edward A; Hochberg Ephraim P; Mellinghoff Ingo K; Hofer Matthias D; Descazeaud Aurelien; Rubin Mark A; Meyerson Matthew; Wong Wing Hung; Sellers William R; Li Cheng
Inferring loss-of-heterozygosity from unpaired tumors using high-density oligonucleotide SNP arrays.
PLoS computational biology 2006;2(5):e41.
2006: Ji Hongbin; Zhao Xiaojun; Yuza Yuki; Shimamura Takeshi; Li Danan; Protopopov Alexei; Jung Boonim L; McNamara Kate; Xia Huili; Glatt Karen A; Thomas Roman K; Sasaki Hidefumi; Horner James W; Eck Michael; Mitchell Albert; Sun Yangping; Al-Hashem Ruqayyah; Bronson Roderick T; Rabindran Sridhar K; Discafani Carolyn M; Maher Elizabeth; Shapiro Geoffrey I; Meyerson Matthew; Wong Kwok-Kin
Epidermal growth factor receptor variant III mutations in lung tumorigenesis and sensitivity to tyrosine kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(20):7817-22.
2006: Alvarez James V; Greulich Heidi; Sellers William R; Meyerson Matthew; Frank David A
Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor.
Cancer research 2006;66(6):3162-8.
2006: Jänne Pasi A; Borras Ana M; Kuang Yanan; Rogers Andrew M; Joshi Victoria A; Liyanage Hema; Lindeman Neal; Lee Jeffrey C; Halmos Balazs; Maher Elizabeth A; Distel Robert J; Meyerson Matthew; Johnson Bruce E
A rapid and sensitive enzymatic method for epidermal growth factor receptor mutation screening.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(3 Pt 1):751-8.
2005: LaFramboise Thomas; Weir Barbara A; Zhao Xiaojun; Beroukhim Rameen; Li Cheng; Harrington David; Sellers William R; Meyerson Matthew
Allele-specific amplification in cancer revealed by SNP array analysis.
PLoS computational biology 2005;1(6):e65.
2005: Greulich Heidi; Chen Tzu-Hsiu; Feng Whei; Jänne Pasi A; Alvarez James V; Zappaterra Mauro; Bulmer Sara E; Frank David A; Hahn William C; Sellers William R; Meyerson Matthew
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.
PLoS medicine 2005;2(11):e313.
2005: Yokoyama Akihiko; Somervaille Tim C P; Smith Kevin S; Rozenblatt-Rosen Orit; Meyerson Matthew; Cleary Michael L
The menin tumor suppressor protein is an essential oncogenic cofactor for MLL-associated leukemogenesis.
Cell 2005;123(2):207-18.
2005: Jiang Jingrui; Greulich Heidi; Jänne Pasi A; Sellers William R; Meyerson Matthew; Griffin James D
Epidermal growth factor-independent transformation of Ba/F3 cells with cancer-derived epidermal growth factor receptor mutants induces gefitinib-sensitive cell cycle progression.
Cancer research 2005;65(19):8968-74.
2005: Karnik Satyajit K; Hughes Christina M; Gu Xueying; Rozenblatt-Rosen Orit; McLean Graeme W; Xiong Yue; Meyerson Matthew; Kim Seung K
Menin regulates pancreatic islet growth by promoting histone methylation and expression of genes encoding p27Kip1 and p18INK4c.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(41):14659-64.
2005: Kobayashi Susumu; Ji Hongbin; Yuza Yuki; Meyerson Matthew; Wong Kwok-Kin; Tenen Daniel G; Halmos Balázs
An alternative inhibitor overcomes resistance caused by a mutation of the epidermal growth factor receptor.
Cancer research 2005;65(16):7096-101.
2005: Garraway Levi A; Widlund Hans R; Rubin Mark A; Getz Gad; Berger Aaron J; Ramaswamy Sridhar; Beroukhim Rameen; Milner Danny A; Granter Scott R; Du Jinyan; Lee Charles; Wagner Stephan N; Li Cheng; Golub Todd R; Rimm David L; Meyerson Matthew L; Fisher David E; Sellers William R
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma.
Nature 2005;436(7047):117-22.
2005: Zhao Xiaojun; Weir Barbara A; LaFramboise Thomas; Lin Ming; Beroukhim Rameen; Garraway Levi; Beheshti Javad; Lee Jeffrey C; Naoki Katsuhiko; Richards William G; Sugarbaker David; Chen Fei; Rubin Mark A; Jänne Pasi A; Girard Luc; Minna John; Christiani David; Li Cheng; Sellers William R; Meyerson Matthew
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.
Cancer research 2005;65(13):5561-70.
2005: Meyerson Matthew; Carbone David
Genomic and proteomic profiling of lung cancers: lung cancer classification in the age of targeted therapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(14):3219-26.
2005: Levine Ross L; Wadleigh Martha; Cools Jan; Ebert Benjamin L; Wernig Gerlinde; Huntly Brian J P; Boggon Titus J; Wlodarska Iwona; Clark Jennifer J; Moore Sandra; Adelsperger Jennifer; Koo Sumin; Lee Jeffrey C; Gabriel Stacey; Mercher Thomas; D'Andrea Alan; Fröhling Stefan; Döhner Konstanze; Marynen Peter; Vandenberghe Peter; Mesa Ruben A; Tefferi Ayalew; Griffin James D; Eck Michael J; Sellers William R; Meyerson Matthew; Golub Todd R; Lee Stephanie J; Gilliland D Gary
Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
Cancer cell 2005;7(4):387-97.
2005: Sellers William R; Meyerson Matthew
EGFR gene mutations: a call for global x global views of cancer.
Journal of the National Cancer Institute 2005;97(5):326-8.
2005: Kobayashi Susumu; Boggon Titus J; Dayaram Tajhal; Jänne Pasi A; Kocher Olivier; Meyerson Matthew; Johnson Bruce E; Eck Michael J; Tenen Daniel G; Halmos Balázs
EGFR mutation and resistance of non-small-cell lung cancer to gefitinib.
The New England journal of medicine 2005;352(8):786-92.
2005: Dobbin Kevin K; Beer David G; Meyerson Matthew; Yeatman Timothy J; Gerald William L; Jacobson James W; Conley Barbara; Buetow Kenneth H; Heiskanen Mervi; Simon Richard M; Minna John D; Girard Luc; Misek David E; Taylor Jeremy M G; Hanash Samir; Naoki Katsuhiko; Hayes D Neil; Ladd-Acosta Christine; Enkemann Steven A; Viale Agnes; Giordano Thomas J
Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):565-72.
2005: Milne Thomas A; Hughes Christina M; Lloyd Ricardo; Yang Zhaohai; Rozenblatt-Rosen Orit; Dou Yali; Schnepp Robert W; Krankel Cynthia; Livolsi Virginia A; Gibbs Denise; Hua Xianxin; Roeder Robert G; Meyerson Matthew; Hess Jay L
Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(3):749-54.
2005: Rozenblatt-Rosen Orit; Hughes Christina M; Nannepaga Suraj J; Shanmugam Kalai Selvi; Copeland Terry D; Guszczynski Tad; Resau James H; Meyerson Matthew
The parafibromin tumor suppressor protein is part of a human Paf1 complex.
Molecular and cellular biology 2005;25(2):612-20.
2005: Cho Daniel; Kocher Olivier; Lee Jeffrey C; Tenen Daniel G; Meyerson Matthew L; Janne Pasi A; Halmos Balazs
Unusual cases in multiple myeloma and a dramatic response in metastatic lung cancer: case 4. Mutation of the epidermal growth factor receptor in an elderly man with advanced, gefitinib-responsive, non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(1):235-7.
2005: Thomas R K; Greulich H; Yuza Y; Lee J C; Tengs T; Feng W; Chen T-H; Nickerson E; Simons J; Egholm M; Rothberg J M; Sellers W R; Meyerson M L
Detection of oncogenic mutations in the EGFR gene in lung adenocarcinoma with differential sensitivity to EGFR tyrosine kinase inhibitors.
Cold Spring Harbor symposia on quantitative biology 2005;70():73-81.
2005: Garraway L A; Weir B A; Zhao X; Widlund H; Beroukhim R; Berger A; Rimm D; Rubin M A; Fisher D E; Meyerson M L; Sellers W R
"Lineage addiction" in human cancer: lessons from integrated genomics.
Cold Spring Harbor symposia on quantitative biology 2005;70():25-34.
2004: Bentires-Alj Mohamed; Paez J Guillermo; David Frank S; Keilhack Heike; Halmos Balazs; Naoki Katsuhiko; Maris John M; Richardson Andrea; Bardelli Alberto; Sugarbaker David J; Richards William G; Du Jinyan; Girard Luc; Minna John D; Loh Mignon L; Fisher David E; Velculescu Victor E; Vogelstein Bert; Meyerson Matthew; Sellers William R; Neel Benjamin G
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.
Cancer research 2004;64(24):8816-20.
2004: Weir Barbara; Zhao Xiaojun; Meyerson Matthew
Somatic alterations in the human cancer genome.
Cancer cell 2004;6(5):433-8.
2004: Tracy Sean; Mukohara Toru; Hansen Mark; Meyerson Matthew; Johnson Bruce E; Jänne Pasi A
Gefitinib induces apoptosis in the EGFRL858R non-small-cell lung cancer cell line H3255.
Cancer research 2004;64(20):7241-4.
2004: Krop Ian; Player Audrey; Tablante Ana; Taylor-Parker Michele; Lahti-Domenici Jaana; Fukuoka Junya; Batra Surinder K; Papadopoulos Nickolas; Richards William G; Sugarbaker David J; Wright Renee L; Shim Judy; Stamey Thomas A; Sellers William R; Loda Massimo; Meyerson Matthew; Hruban Ralph; Jen Jin; Polyak Kornelia
Frequent HIN-1 promoter methylation and lack of expression in multiple human tumor types.
Molecular cancer research : MCR 2004;2(9):489-94.
2004: Jiang Jingrui; Paez J Guillermo; Lee Jeffrey C; Bo Ronghai; Stone Richard M; DeAngelo Daniel J; Galinsky Ilene; Wolpin Brian M; Jonasova Anna; Herman Paula; Fox Edward A; Boggon Titus J; Eck Michael J; Weisberg Ellen; Griffin James D; Gilliland D Gary; Meyerson Matthew; Sellers William R
Identifying and characterizing a novel activating mutation of the FLT3 tyrosine kinase in AML.
Blood 2004;104(6):1855-8.
2004: Dubinett Steven M; Elashoff David; Meyerson Matthew
Assessing prognosis in non-small-cell lung cancer: avenues to a more complete picture?
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(16):3209-11.
2004: Paez J Guillermo; Jänne Pasi A; Lee Jeffrey C; Tracy Sean; Greulich Heidi; Gabriel Stacey; Herman Paula; Kaye Frederic J; Lindeman Neal; Boggon Titus J; Naoki Katsuhiko; Sasaki Hidefumi; Fujii Yoshitaka; Eck Michael J; Sellers William R; Johnson Bruce E; Meyerson Matthew
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy.
Science (New York, N.Y.) 2004;304(5676):1497-500.
2004: Zhao Xiaojun; Li Cheng; Paez J Guillermo; Chin Koei; Jänne Pasi A; Chen Tzu-Hsiu; Girard Luc; Minna John; Christiani David; Leo Chris; Gray Joe W; Sellers William R; Meyerson Matthew
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays.
Cancer research 2004;64(9):3060-71.
2004: Jänne Pasi A; Li Cheng; Zhao Xiaojun; Girard Luc; Chen Tzu-Hsiu; Minna John; Christiani David C; Johnson Bruce E; Meyerson Matthew
High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines.
Oncogene 2004;23(15):2716-26.
2004: Hughes Christina M; Rozenblatt-Rosen Orit; Milne Thomas A; Copeland Terry D; Levine Stuart S; Lee Jeffrey C; Hayes D Neil; Shanmugam Kalai Selvi; Bhattacharjee Arindam; Biondi Christine A; Kay Graham F; Hayward Nicholas K; Hess Jay L; Meyerson Matthew
Menin associates with a trithorax family histone methyltransferase complex and with the hoxc8 locus.
Molecular cell 2004;13(4):587-97.
2004: Meyerson Matthew; Franklin Wilbur A; Kelley Michael J
Molecular classification and molecular genetics of human lung cancers.
Seminars in oncology 2004;31(1 Suppl 1):4-19.
2004: Scacheri Peter C; Rozenblatt-Rosen Orit; Caplen Natasha J; Wolfsberg Tyra G; Umayam Lowell; Lee Jeffrey C; Hughes Christina M; Shanmugam Kalai Selvi; Bhattacharjee Arindam; Meyerson Matthew; Collins Francis S
Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(7):1892-7.
2004: Wang Zhigang C; Lin Ming; Wei Lee-Jen; Li Cheng; Miron Alexander; Lodeiro Gabriella; Harris Lyndsay; Ramaswamy Sridhar; Tanenbaum David M; Meyerson Matthew; Iglehart James D; Richardson Andrea
Loss of heterozygosity and its correlation with expression profiles in subclasses of invasive breast cancers.
Cancer research 2004;64(1):64-71.
2004: Tengs Torstein; LaFramboise Thomas; Den Robert B; Hayes David N; Zhang Jianhua; DebRoy Saikat; Gentleman Robert C; O'Neill Keith; Birren Bruce; Meyerson Matthew
Genomic representations using concatenates of Type IIB restriction endonuclease digestion fragments.
Nucleic acids research 2004;32(15):e121.
2004: Paez J Guillermo; Lin Ming; Beroukhim Rameen; Lee Jeffrey C; Zhao Xiaojun; Richter Daniel J; Gabriel Stacey; Herman Paula; Sasaki Hidefumi; Altshuler David; Li Cheng; Meyerson Matthew; Sellers William R
Genome coverage and sequence fidelity of phi29 polymerase-based multiple strand displacement whole genome amplification.
Nucleic acids research 2004;32(9):e71.
2003: Lieberfarb Marshall E; Lin Ming; Lechpammer Mirna; Li Cheng; Tanenbaum David M; Febbo Phillip G; Wright Renée L; Shim Judy; Kantoff Philip W; Loda Massimo; Meyerson Matthew; Sellers William R
Genome-wide loss of heterozygosity analysis from laser capture microdissected prostate cancer using single nucleotide polymorphic allele (SNP) arrays and a novel bioinformatics platform dChipSNP.
Cancer research 2003;63(16):4781-5.
2003: Meyerson Matthew
Human genetic variation and disease.
Lancet 2003;362(9380):259-60.
2003: Xu Yaohui; Stange-Thomann Nicole; Weber Griffin; Bo Ronghai; Dodge Sheila; David Robert G; Foley Karen; Beheshti Javad; Harris Nancy L; Birren Bruce; Lander Eric S; Meyerson Matthew
Pathogen discovery from human tissue by sequence-based computational subtraction.
Genomics 2003;81(3):329-35.
2002: Naoki Katsuhiko; Chen Tzu-Hsiu; Richards William G; Sugarbaker David J; Meyerson Matthew
Missense mutations of the BRAF gene in human lung adenocarcinoma.
Cancer research 2002;62(23):7001-3.
2002: Weber Griffin; Shendure Jay; Tanenbaum David M; Church George M; Meyerson Matthew
Identification of foreign gene sequences by transcript filtering against the human genome.
Nature genetics 2002;30(2):141-2.
2001: Bhattacharjee A; Richards W G; Staunton J; Li C; Monti S; Vasa P; Ladd C; Beheshti J; Bueno R; Gillette M; Loda M; Weber G; Mark E J; Lander E S; Wong W; Johnson B E; Golub T R; Sugarbaker D J; Meyerson M
Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13790-5.
2001: Hahn W C; Meyerson M
Telomerase activation, cellular immortalization and cancer.
Annals of medicine 2001;33(2):123-9.
2000: Lindblad-Toh K; Tanenbaum D M; Daly M J; Winchester E; Lui W O; Villapakkam A; Stanton S E; Larsson C; Hudson T J; Johnson B E; Lander E S; Meyerson M
Loss-of-heterozygosity analysis of small-cell lung carcinomas using single-nucleotide polymorphism arrays.
Nature biotechnology 2000;18(9):1001-5.
2000: Meyerson M
Role of telomerase in normal and cancer cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(13):2626-34.
2000: Stanton S E; Shin S W; Johnson B E; Meyerson M
Recurrent allelic deletions of chromosome arms 15q and 16q in human small cell lung carcinomas.
Genes, chromosomes & cancer 2000;27(3):323-31.
1999: Hahn W C; Stewart S A; Brooks M W; York S G; Eaton E; Kurachi A; Beijersbergen R L; Knoll J H; Meyerson M; Weinberg R A
Inhibition of telomerase limits the growth of human cancer cells.
Nature medicine 1999;5(10):1164-70.
1998: Meyerson M
Telomerase enzyme activation and human cell immortalization.
Toxicology letters 1998;102-103():41-5.
1998: Kolquist K A; Ellisen L W; Counter C M; Meyerson M; Tan L K; Weinberg R A; Haber D A; Gerald W L
Expression of TERT in early premalignant lesions and a subset of cells in normal tissues.
Nature genetics 1998;19(2):182-6.
1998: Counter C M; Meyerson M; Eaton E N; Ellisen L W; Caddle S D; Haber D A; Weinberg R A
Telomerase activity is restored in human cells by ectopic expression of hTERT (hEST2), the catalytic subunit of telomerase.
Oncogene 1998;16(9):1217-22.
1997: Meyerson M; Counter C M; Eaton E N; Ellisen L W; Steiner P; Caddle S D; Ziaugra L; Beijersbergen R L; Davidoff M J; Liu Q; Bacchetti S; Haber D A; Weinberg R A
hEST2, the putative human telomerase catalytic subunit gene, is up-regulated in tumor cells and during immortalization.
Cell 1997;90(4):785-95.
1997: Counter C M; Meyerson M; Eaton E N; Weinberg R A
The catalytic subunit of yeast telomerase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(17):9202-7.
1994: Meyerson M; Harlow E
Identification of G1 kinase activity for cdk6, a novel cyclin D partner.
Molecular and cellular biology 1994;14(3):2077-86.
1992: Meyerson M; Enders G H; Wu C L; Su L K; Gorka C; Nelson C; Harlow E; Tsai L H
A family of human cdc2-related protein kinases.
The EMBO journal 1992;11(8):2909-17.
1992: Yarrish R L; Shay W; LaBombardi V J; Meyerson M; Miller D K; Larone D
Osteomyelitis caused by Mycobacterium haemophilum: successful therapy in two patients with AIDS.
AIDS (London, England) 1992;6(6):557-61.
1991: Tsai L H; Harlow E; Meyerson M
Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase.
Nature 1991;353(6340):174-7.
1991: Meyerson M; Faha B; Su L K; Harlow E; Tsai L H
The cyclin-dependent kinase family.
Cold Spring Harbor symposia on quantitative biology 1991;56():177-86.

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