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Liliane Michalik

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Walter Wahli; Liliane Michalik
PPARs at the crossroads of lipid signaling and inflammation.
Alexandra Montagner; Gianpaolo Rando; Gwendoline Degueurce; Nicolas Leuenberger; Liliane Michalik; Walter Wahli
New insights into the role of PPARs.
Genta Plasari; Alessandra Calabrese; Yves Dusserre; Richard M Gronostajski; Alan McNair; Liliane Michalik; Nicolas Mermod
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression.

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All Publications

2012: Walter Wahli; Liliane Michalik
PPARs at the crossroads of lipid signaling and inflammation.
Trends in endocrinology and metabolism: TEM 2012;23(7):351-63.
2011: Alexandra Montagner; Gianpaolo Rando; Gwendoline Degueurce; Nicolas Leuenberger; Liliane Michalik; Walter Wahli
New insights into the role of PPARs.
Prostaglandins, leukotrienes, and essential fatty acids 2011;85(5):235-43.
2009: Genta Plasari; Alessandra Calabrese; Yves Dusserre; Richard M Gronostajski; Alan McNair; Liliane Michalik; Nicolas Mermod
Nuclear factor I-C links platelet-derived growth factor and transforming growth factor beta1 signaling to skin wound healing progression.
Molecular and cellular biology 2009;29(22):6006-17.
2008: Liliane Michalik; Walter Wahli
PPARs Mediate Lipid Signaling in Inflammation and Cancer.
PPAR research 2008;2008():134059.
2007: Nguan Soon Tan; Guillaume Icre; Alexandra Montagner; Béatrice Bordier-ten-Heggeler; Walter Wahli; Liliane Michalik
The nuclear hormone receptor peroxisome proliferator-activated receptor beta/delta potentiates cell chemotactism, polarization, and migration.
Molecular and cellular biology 2007;27(20):7161-75.
2007: Liliane Michalik; Walter Wahli
Peroxisome proliferator-activated receptors (PPARs) in skin health, repair and disease.
Biochimica et biophysica acta 2007;1771(8):991-8.
2007: Liliane Michalik; Walter Wahli
Guiding ligands to nuclear receptors.
Cell 2007;129(4):649-51.
2007: Liliane Michalik; Vincent Zoete; Grigorios Krey; Aurélien Grosdidier; Laurent Gelman; Pierre Chodanowski; Jerome N Feige; Béatrice Desvergne; Walter Wahli; Olivier Michielin
Combined simulation and mutagenesis analyses reveal the involvement of key residues for peroxisome proliferator-activated receptor alpha helix 12 dynamic behavior.
The Journal of biological chemistry 2007;282(13):9666-77.
2006: Liliane Michalik; Johan Auwerx; Joel P Berger; V Krishna Chatterjee; Christopher K Glass; Frank J Gonzalez; Paul A Grimaldi; Takashi Kadowaki; Mitchell Lazar; Stephen O'Rahilly; Colin N A Palmer; Jorge Plutzky; Janardan K Reddy; Bruce M Spiegelman; Bart Staels; Walter Wahli
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors.
Pharmacological reviews 2006;58(4):726-41.
2006: Guillaume Icre; Walter Wahli; Liliane Michalik
Functions of the peroxisome proliferator-activated receptor (PPAR) alpha and beta in skin homeostasis, epithelial repair, and morphogenesis.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2006;11(1):30-5.
2006: Laurence Canaple; Juliette Rambaud; Ouria Dkhissi-Benyahya; Béatrice Rayet; Nguan Soon Tan; Liliane Michalik; Franck Delaunay; Walter Wahli; Vincent Laudet
Reciprocal regulation of brain and muscle Arnt-like protein 1 and peroxisome proliferator-activated receptor alpha defines a novel positive feedback loop in the rodent liver circadian clock.
Molecular endocrinology (Baltimore, Md.) 2006;20(8):1715-27.
2006: Béatrice Desvergne; Liliane Michalik; Walter Wahli
Transcriptional regulation of metabolism.
Physiological reviews 2006;86(2):465-514.
2006: Liliane Michalik; Walter Wahli
Involvement of PPAR nuclear receptors in tissue injury and wound repair.
The Journal of clinical investigation 2006;116(3):598-606.
2006: Jerome N Feige; Laurent Gelman; Liliane Michalik; Béatrice Desvergne; Walter Wahli
From molecular action to physiological outputs: peroxisome proliferator-activated receptors are nuclear receptors at the crossroads of key cellular functions.
Progress in lipid research 2006;45(2):120-59.
2005: Nicolas Di-Poï; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Transcriptional repression of peroxisome proliferator-activated receptor beta/delta in murine keratinocytes by CCAAT/enhancer-binding proteins.
The Journal of biological chemistry 2005;280(46):38700-10.
2005: Liliane Michalik; Jerome N Feige; Laurent Gelman; Thierry Pedrazzini; H Keller; Béatrice Desvergne; Walter Wahli
Selective expression of a dominant-negative form of peroxisome proliferator-activated receptor in keratinocytes leads to impaired epidermal healing.
Molecular endocrinology (Baltimore, Md.) 2005;19(9):2335-48.
2005: Raphael Genolet; Sander Kersten; Olivier Braissant; Stéphane Mandard; Nguan Soon Tan; Philipp Bucher; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.
The Journal of biological chemistry 2005;280(25):24143-52.
2005: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Genetic- or transforming growth factor-beta 1-induced changes in epidermal peroxisome proliferator-activated receptor beta/delta expression dictate wound repair kinetics.
The Journal of biological chemistry 2005;280(18):18163-70.
2005: Laurent Gelman; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Kinase signaling cascades that modulate peroxisome proliferator-activated receptors.
Current opinion in cell biology 2005;17(2):216-22.
2005: Nicolas Di-Poï; Chuan Young Ng; Nguan Soon Tan; Zhongzhou Yang; Brian A Hemmings; Béatrice Desvergne; Liliane Michalik; Walter Wahli
Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development.
Molecular and cellular biology 2005;25(5):1696-712.
2005: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Multiple expression control mechanisms of peroxisome proliferator-activated receptors and their target genes.
The Journal of steroid biochemistry and molecular biology 2005;93(2-5):99-105.
2005: Radina Kostadinova; Walter Wahli; Liliane Michalik
PPARs in diseases: control mechanisms of inflammation.
Current medicinal chemistry 2005;12(25):2995-3009.
2005: Sandrine Gremlich; Christopher Nolan; Raphael Roduit; Rémy Burcelin; Marie-Line Peyot; Viviane Delghingaro-Augusto; Béatrice Desvergne; Liliane Michalik; Marc Prentki; Walter Wahli
Pancreatic islet adaptation to fasting is dependent on peroxisome proliferator-activated receptor alpha transcriptional up-regulation of fatty acid oxidation.
Endocrinology 2005;146(1):375-82.
2004: Raphael Genolet; Walter Wahli; Liliane Michalik
PPARs as drug targets to modulate inflammatory responses?
Current drug targets. Inflammation and allergy 2004;3(4):361-75.
2004: Nicolas Di-Poï; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Functions of peroxisome proliferator-activated receptors (PPAR) in skin homeostasis.
Lipids 2004;39(11):1093-9.
2004: Nguan Soon Tan; Liliane Michalik; Nicolas Di-Poï; Chuan Young Ng; Nicolas Mermod; Anita B Roberts; Béatrice Desvergne; Walter Wahli
Essential role of Smad3 in the inhibition of inflammation-induced PPARbeta/delta expression.
The EMBO journal 2004;23(21):4211-21.
2004: Jennifer Rieusset; Josiane Seydoux; Silvia I Anghel; Pascal Escher; Liliane Michalik; Nguan Soon Tan; Daniel Metzger; Pierre Chambon; Walter Wahli; Béatrice Desvergne
Altered growth in male peroxisome proliferator-activated receptor gamma (PPARgamma) heterozygous mice: involvement of PPARgamma in a negative feedback regulation of growth hormone action.
Molecular endocrinology (Baltimore, Md.) 2004;18(10):2363-77.
2004: Béatrice Desvergne; Liliane Michalik; Walter Wahli
Be fit or be sick: peroxisome proliferator-activated receptors are down the road.
Molecular endocrinology (Baltimore, Md.) 2004;18(6):1321-32.
2004: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptor-beta as a target for wound healing drugs.
Expert opinion on therapeutic targets 2004;8(1):39-48.
2004: Nguan Soon Tan; Liliane Michalik; Nicolas Di-Poï; Béatrice Desvergne; Walter Wahli
Critical roles of the nuclear receptor PPARbeta (peroxisome-proliferator-activated receptor beta) in skin wound healing.
Biochemical Society transactions 2004;32(Pt 1):97-102.
2004: Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome-proliferator-activated receptors and cancers: complex stories.
Nature reviews. Cancer 2004;4(1):61-70.
2003: Nicolas Di-Poï; Liliane Michalik; Nguan Soon Tan; Béatrice Desvergne; Walter Wahli
The anti-apoptotic role of PPARbeta contributes to efficient skin wound healing.
The Journal of steroid biochemistry and molecular biology 2003;85(2-5):257-65.
2003: Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptors beta/delta: emerging roles for a previously neglected third family member.
Current opinion in lipidology 2003;14(2):129-35.
2003: Nguan Soon Tan; Liliane Michalik; Béatrice Desvergne; Walter Wahli
Peroxisome proliferator-activated receptor (PPAR)-beta as a target for wound healing drugs: what is possible?
American journal of clinical dermatology 2003;4(8):523-30.
2002: Jennifer Rieusset; Fethi Touri; Liliane Michalik; Pascal Escher; Béatrice Desvergne; Eric Niesor; Walter Wahli
A new selective peroxisome proliferator-activated receptor gamma antagonist with antiobesity and antidiabetic activity.
Molecular endocrinology (Baltimore, Md.) 2002;16(11):2628-44.
2002: Nicolas Di-Poï; Nguan Soon Tan; Liliane Michalik; Walter Wahli; Béatrice Desvergne
Antiapoptotic role of PPARbeta in keratinocytes via transcriptional control of the Akt1 signaling pathway.
Molecular cell 2002;10(4):721-33.
2002: AK Hihi; Liliane Michalik; Walter Wahli
PPARs: transcriptional effectors of fatty acids and their derivatives.
Cellular and molecular life sciences : CMLS 2002;59(5):790-8.
2002: Liliane Michalik; Béatrice Desvergne; Christine Dreyer; Mathilde Gavillet; Ricardo Laurini; Walter Wahli
PPAR expression and function during vertebrate development.
The International journal of developmental biology 2002;46(1):105-14.
2001: Nguan Soon Tan; Liliane Michalik; Noa Noy; Rubina Yasmin; C Pacot; M Heim; B Flühmann; Béatrice Desvergne; Walter Wahli
Critical roles of PPAR beta/delta in keratinocyte response to inflammation.
Genes & development 2001;15(24):3263-77.
2001: Pascal Escher; Olivier Braissant; Sharmila Basu-Modak; Liliane Michalik; Walter Wahli; Béatrice Desvergne
Rat PPARs: quantitative analysis in adult rat tissues and regulation in fasting and refeeding.
Endocrinology 2001;142(10):4195-202.
2001: Liliane Michalik; Béatrice Desvergne; Nguan Soon Tan; Sharmila Basu-Modak; Pascal Escher; Jennifer Rieusset; J M Peters; G Kaya; FJ Gonzalez; Jozsef Zakany; Daniel Metzger; Pierre Chambon; D Duboule; Walter Wahli
Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice.
The Journal of cell biology 2001;154(4):799-814.
2000: Liliane Michalik; Béatrice Desvergne; Sharmila Basu-Modak; Nguan Soon Tan; Walter Wahli
Nuclear hormone receptors and mouse skin homeostasis: implication of PPARbeta.
Hormone research 2000;54(5-6):263-8.
1999: Liliane Michalik; W Wahli
Peroxisome proliferator-activated receptors: three isotypes for a multitude of functions.
Current opinion in biotechnology 1999;10(6):564-70.