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Martin Michel

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Peter Ochodnický; Jalesh N Panicker; Jai Seth; Jan J Butter; Martina B Michel; Martin C Michel
Bradykinin modulates spontaneous nerve growth factor production and stretch-induced ATP release in human urothelium.
Christine A Teitsma; Jean J M C H de la Rosette; Martin C Michel
Are polymorphisms of the β(3)-adrenoceptor gene associated with an altered bladder function?
Adrian Wagg; David Weinstein; Caty E Bitoun; Amanda Darekar; Vik Khullar; Daniela Marschall-Kehrel; Martin C Michel; Matthias Oelke; Ian Osterloh
Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial.

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2013: Peter Ochodnický; Jalesh N Panicker; Jai Seth; Jan J Butter; Martina B Michel; Martin C Michel
Bradykinin modulates spontaneous nerve growth factor production and stretch-induced ATP release in human urothelium.
Pharmacological research : the official journal of the Italian Pharmacological Society 2013;70(1):147-54.
2013: Christine A Teitsma; Jean J M C H de la Rosette; Martin C Michel
Are polymorphisms of the β(3)-adrenoceptor gene associated with an altered bladder function?
Neurourology and urodynamics 2013;32(3):276-80.
2013: Adrian Wagg; David Weinstein; Caty E Bitoun; Amanda Darekar; Vik Khullar; Daniela Marschall-Kehrel; Martin C Michel; Matthias Oelke; Ian Osterloh
Flexible-dose fesoterodine in elderly adults with overactive bladder: results of the randomized, double-blind, placebo-controlled study of fesoterodine in an aging population trial.
Journal of the American Geriatrics Society 2013;61(2):185-93.
2012: Barbara Frias; Martin C Michel; António Avelino; Ana Charrua; Francisco Cruz; Célia D Cruz
Transient receptor potential vanilloid 1 mediates nerve growth factor-induced bladder hyperactivity and noxious input.
BJU international 2012;110(8 Pt B):E422-8.
2012: Hana Cernecka; Wouter H Lamers; Peter Ochodnicky; Martin C Michel
Specificity evaluation of antibodies against human β3-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 2012;385(9):875-82.
2012: Peter Ochodnický; Mirjana Poljakovic; Peter Wiklund; Rachel Eccles; Sian Humphreys; Martin C Michel
Expression profiling of G-protein-coupled receptors in human urothelium and related cell lines.
BJU international 2012;110(6 Pt B):E293-300.
2012: Martin C Michel; Piotr Radziszewski; Christian Falconer; Daniela Marschall-Kehrel; Koenraad Blot
Unexpected frequent hepatotoxicity of a prescription drug, flupirtine, marketed for about 30 years.
British journal of clinical pharmacology 2012;73(5):821-5.
2012: Henricus G Ruhé; Jan Booij; Martin C Michel; Dick J Veltman; Aart H Schene
Successful pharmacologic treatment of major depressive disorder attenuates amygdala activation to negative facial expressions: a functional magnetic resonance imaging study.
The Journal of clinical psychiatry 2012;73(4):451-9.
2011: Lambertus P W Witte; Eric L Stangeland; Tod Steinfeld; Jayashree Aiyar; Noach de Haas; Mathai Mammen; Martin C Michel
Muscarinic receptor subtypes and signalling involved in the attenuation of isoprenaline-induced rat urinary bladder relaxation.
Naunyn-Schmiedeberg's archives of pharmacology 2011;384(6):555-63.
2011: Peter Ochodnický; Naoki Yoshimura; Célia D Cruz; Martin C Michel
Nerve growth factor in bladder dysfunction: contributing factor, biomarker, and therapeutic target.
Neurourology and urodynamics 2011;30(7):1227-41.
2011: Martin C Michel
Clinical pharmacology of functional disorders of the urogenital system.
British journal of clinical pharmacology 2011;72(2):183-5.
2011: Joachim Troost; Yasuhiro Tsuda; Martina Wein; Michaela Mattheus; Ludwig Mehlburger; Shinji Tatami; Martin C Michel
Effects of strong CYP2D6 and 3A4 inhibitors, paroxetine and ketoconazole, on the pharmacokinetics and cardiovascular safety of tamsulosin.
British journal of clinical pharmacology 2011;72(2):247-56.
2011: Martin C Michel; Peter Ochodnicky; Yukio Homma; Yasuhiko Igawa
β-adrenoceptor agonist effects in experimental models of bladder dysfunction.
Pharmacology & therapeutics 2011;131(1):40-9.
2011: Martin C Michel; Hana Cernecka; Peter Ochodnicky
Desirable properties of β3-adrenoceptor agonists: implications for the selection of drug development candidates.
European journal of pharmacology 2011;657(1-3):1-3.
2011: Elfaridah P Frazier; Martina B Michel-Reher; Pieter van Loenen; Carsten Sand; Tim Schneider; Stephan L M Peters; Martin C Michel
Lack of evidence that nebivolol is a β₃-adrenoceptor agonist.
European journal of pharmacology 2011;654(1):86-91.
2011: Martin C Michel; Sian E Harding; Richard A Bond
Are there functional β₃-adrenoceptors in the human heart?
British journal of pharmacology 2011;162(4):817-22.
2011: Tim Schneider; Charlotte Fetscher; Martin C Michel
Human Urinary Bladder Strip Relaxation by the β-Adrenoceptor Agonist Isoprenaline: Methodological Considerations and Effects of Gender and Age.
Frontiers in pharmacology 2011;2():11.
2011: Martin C Michel
β-Adrenergic Receptor Subtypes in the Urinary Tract.
Handbook of experimental pharmacology 2011;(202):307-18.
2010: Nazha Hamdani; Attila Borbély; Sophie P G R Veenstra; Viola Kooij; Wim Vrydag; Ruud Zaremba; Cris Dos Remedios; Hans W M Niessen; Martin C Michel; Walter J Paulus; Ger J M Stienen; Dirk Duncker
More severe cellular phenotype in human idiopathic dilated cardiomyopathy compared to ischemic heart disease.
Journal of muscle research and cell motility 2010;31(4):289-301.
2010: Martin C Michel; Peter Ochodnicky; Roger J Summers
Tissue functions mediated by beta(3)-adrenoceptors-findings and challenges.
Naunyn-Schmiedeberg's archives of pharmacology 2010;382(2):103-8.
2010: Marleen M van Dijk; Hessel Wijkstra; Jean J M C H de la Rosette; Frans M Debruyne; Martin C Michel
The role of nocturia in the quality of life of men with lower urinary tract symptoms.
BJU international 2010;105(8):1141-6.
2010: Gabriela Franco-Salinas; Jean J M C H de la Rosette; Martin C Michel
Pharmacokinetics and pharmacodynamics of tamsulosin in its modified-release and oral controlled absorption system formulations.
Clinical pharmacokinetics 2010;49(3):177-88.
2010: Martin C Michel
Challenges in the pharmacotherapy of urogenital disorders.
Frontiers in pharmacology 2010;1():117.
2010: Martin C Michel
The forefront for novel therapeutic agents based on the pathophysiology of lower urinary tract dysfunction: alpha-blockers in the treatment of male voiding dysfunction - how do they work and why do they differ in tolerability?
Journal of pharmacological sciences 2010;112(2):151-7.
2009: Martin C Michel; Christopher Chapple
Basic mechanisms of urgency: preclinical and clinical evidence.
European urology 2009;56(2):298-307.
2009: M Jongsma; J van Unen; P B van Loenen; Martin C Michel; Stephan L M Peters; Astrid E Alewijnse
Different response patterns of several ligands at the sphingosine-1-phosphate receptor subtype 3 (S1P(3)).
British journal of pharmacology 2009;156(8):1305-11.
2009: Martin C Michel; Thomas Wieland; Gozoh Tsujimoto
How reliable are G-protein-coupled receptor antibodies?
Naunyn-Schmiedeberg's archives of pharmacology 2009;379(4):385-8.
2009: Marielle Hendriks-Balk; Najat Hajji; Pieter B van Loenen; Martin C Michel; Stephan L M Peters; Astrid E Alewijnse
Sphingosine-1-phosphate regulates RGS2 and RGS16 mRNA expression in vascular smooth muscle cells.
European journal of pharmacology 2009;606(1-3):25-31.
2009: Martin C Michel; R F Schäfers; J J M C H de la Rosette
[Drug-drug interactions in urology].
Der Urologe. Ausg. A 2009;48(3):264-9.
2009: Wim Vrydag; Astrid E Alewijnse; Martin C Michel
Do gene polymorphisms alone or in combination affect the function of human beta3-adrenoceptors?
British journal of pharmacology 2009;156(1):127-34.
2009: Lambertus P W Witte; Wilhemina M C Mulder; Jean J M C H de la Rosette; Martin C Michel
Muscarinic receptor antagonists for overactive bladder treatment: does one fit all?
Current opinion in urology 2009;19(1):13-9.
2009: Maurits M Barendrecht; Elfaridah P Frazier; Wim Vrydag; Astrid E Alewijnse; Stephan L M Peters; Martin C Michel
The effect of bladder outlet obstruction on alpha1- and beta-adrenoceptor expression and function.
Neurourology and urodynamics 2009;28(4):349-55.
2008: Marielle Hendriks-Balk; Pieter B van Loenen; Najat Hajji; Martin C Michel; Stephan L M Peters; Astrid E Alewijnse
S1P receptor signalling and RGS proteins; expression and function in vascular smooth muscle cells and transfected CHO cells.
European journal of pharmacology 2008;600(1-3):1-9.
2008: Martin C Michel; Rainer Büscher
Beta2-adrenergic receptor gene polymorphisms: will the important one please step forward?
Journal of the American College of Cardiology 2008;52(17):1389-90.
2008: Hester van Diepen; Eberhard Schlicker; Martin C Michel
Prejunctional and peripheral effects of the cannabinoid CB(1) receptor inverse agonist rimonabant (SR 141716).
Naunyn-Schmiedeberg's archives of pharmacology 2008;378(4):345-69.
2008: Martin C Michel; Sergio Parra
Similarities and differences in the autonomic control of airway and urinary bladder smooth muscle.
Naunyn-Schmiedeberg's archives of pharmacology 2008;378(2):217-24.
2008: Elfaridah P Frazier; Stephan L M Peters; Alan S Braverman; Michael Ruggieri; Martin C Michel
Signal transduction underlying the control of urinary bladder smooth muscle tone by muscarinic receptors and beta-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 2008;377(4-6):449-62.
2008: Marielle Hendriks-Balk; Stephan L M Peters; Martin C Michel; Astrid E Alewijnse
Regulation of G protein-coupled receptor signalling: focus on the cardiovascular system and regulator of G protein signalling proteins.
European journal of pharmacology 2008;585(2-3):278-91.
2008: Martin C Michel; Eric Fliers; Cornelis J F Van Noorden
Dipeptidyl peptidase IV inhibitors in diabetes: more than inhibition of glucagon-like peptide-1 metabolism?
Naunyn-Schmiedeberg's archives of pharmacology 2008;377(3):205-7.
2008: Martin C Michel; Maurits M Barendrecht
Physiological and pathological regulation of the autonomic control of urinary bladder contractility.
Pharmacology & therapeutics 2008;117(3):297-312.
2008: Martin C Michel
Editorial comment on: distribution and function of the hydrogen sulfide-sensitive TRPA1 ion channel in rat urinary bladder.
European urology 2008;53(2):399-400.
2008: Peter Tsakiris; Matthias Oelke; Martin C Michel
Drug-induced urinary incontinence.
Drugs & aging 2008;25(7):541-9.
2008: Martin C Michel; Ulrich Wetterauer; Monika Vogel; Jean J M C H de la Rosette
Cardiovascular safety and overall tolerability of solifenacin in routine clinical use: a 12-week, open-label, post-marketing surveillance study.
Drug safety : an international journal of medical toxicology and drug experience 2008;31(6):505-14.
2008: Peter Tsakiris; Jean J M C H de la Rosette; Martin C Michel; Matthias Oelke
Pharmacologic treatment of male stress urinary incontinence: systematic review of the literature and levels of evidence.
European urology 2008;53(1):53-9.
2008: Maurits M Barendrecht; Paul Abrams; Helmut Schumacher; Jean J M C H de la Rosette; Martin C Michel
Do alpha1-adrenoceptor antagonists improve lower urinary tract symptoms by reducing bladder outlet resistance?
Neurourology and urodynamics 2008;27(3):226-30.
2007: Martin C Michel; Astrid E Alewijnse
Ligand-directed signaling: 50 ways to find a lover.
Molecular pharmacology 2007;72(5):1097-9.
2007: A C M Mulders; S Nau; Y Li; Martin C Michel
Effects of sphingosine-1-phosphate and sphingosylphosphorylcholine on intracellular Ca2+ and cell death in prostate cancer cell lines.
Autonomic & autacoid pharmacology 2007;27(4):173-9.
2007: Martin C Michel
Alpha1-adrenoceptors and ejaculatory function.
British journal of pharmacology 2007;152(3):289-90.
2007: Elfaridah P Frazier; Alan S Braverman; Stephan L M Peters; Martin C Michel; Michael Ruggieri
Does phospholipase C mediate muscarinic receptor-induced rat urinary bladder contraction?
The Journal of pharmacology and experimental therapeutics 2007;322(3):998-1002.
2007: Martin C Michel
Although the phosphodiesterase inhibitors have revolutionised the treatment of ED, postoperative ED due to nerve damage remains a therapeutic challenge.
European urology 2007;52(2):580-1.
2007: Maikel Jongsma; Urszula M Florczyk; Marielle Hendriks-Balk; Martin C Michel; Stephan L M Peters; Astrid E Alewijnse
Validation of a rapid, non-radioactive method to quantify internalisation of G-protein coupled receptors.
Naunyn-Schmiedeberg's archives of pharmacology 2007;375(5):329-36.
2007: Maurits M Barendrecht; Arthur C M Mulders; Henk van der Poel; Maurice J B Van Den Hoff; Martina Schmidt; Martin C Michel
Role of transforming growth factor beta in rat bladder smooth muscle cell proliferation.
The Journal of pharmacology and experimental therapeutics 2007;322(1):117-22.
2007: Marielle Hendriks-Balk; Martin C Michel; Astrid E Alewijnse
Pitfalls in the normalization of real-time polymerase chain reaction data.
Basic research in cardiology 2007;102(3):195-7.
2007: Martin C Michel; Arthur C M Mulders; Maikel Jongsma; Astrid E Alewijnse; Stephan L M Peters
Vascular effects of sphingolipids.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2007;96(455):44-8.
2007: Arthur C M Mulders; Stephan L M Peters; Martin C Michel
Sphingomyelin metabolism and endothelial cell function.
European heart journal 2007;28(7):777-9.
2007: Maurits M Barendrecht; Matthias Oelke; M Pilar Laguna; Martin C Michel
Is the use of parasympathomimetics for treating an underactive urinary bladder evidence-based?
BJU international 2007;99(4):749-52.
2007: Wim Vrydag; Martin C Michel
Tools to study beta3-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 2007;374(5-6):385-98.
2007: Maurits M Barendrecht; P Chichester; Martin C Michel; R M Levin
Effect of short-term outlet obstruction on rat bladder nerve density and contractility.
Autonomic & autacoid pharmacology 2007;27(1):47-53.
2007: Martin C Michel; Matthias Oelke; Mark Goepel; Elmar Beck; Martin Burkart
Relationships among symptoms, bother, and treatment satisfaction in overactive bladder patients.
Neurourology and urodynamics 2007;26(2):190-5.
2006: Nadja Niclauss; Martina B Michel-Reher; Astrid E Alewijnse; Martin C Michel
Comparison of three radioligands for the labelling of human beta-adrenoceptor subtypes.
Naunyn-Schmiedeberg's archives of pharmacology 2006;374(2):99-105.
2006: Martin C Michel; Sharath S Hegde
Treatment of the overactive bladder syndrome with muscarinic receptor antagonists: a matter of metabolites?
Naunyn-Schmiedeberg's archives of pharmacology 2006;374(2):79-85.
2006: Maxim Hardziyenka; Maria E Campian; H A C M Rianne de Bruin-Bon; Martin C Michel; Hanno L Tan
Sequence of echocardiographic changes during development of right ventricular failure in rat.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2006;19(10):1272-9.
2006: Maikel Jongsma; Marielle Hendriks-Balk; Martin C Michel; Stephan L M Peters; Astrid E Alewijnse
BML-241 fails to display selective antagonism at the sphingosine-1-phosphate receptor, S1P(3).
British journal of pharmacology 2006;149(3):277-82.
2006: Maria E Campian; Maxim Hardziyenka; Martin C Michel; Hanno L Tan
How valid are animal models to evaluate treatments for pulmonary hypertension?
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(6):391-400.
2006: Stephan L M Peters; Martina Schmidt; Martin C Michel
Rho kinase: a target for treating urinary bladder dysfunction?
Trends in pharmacological sciences 2006;27(9):492-7.
2006: Arthur C M Mulders; Marielle Hendriks-Balk; Marie-Jeanne Mathy; Martin C Michel; Astrid E Alewijnse; Stephan L M Peters
Sphingosine kinase-dependent activation of endothelial nitric oxide synthase by angiotensin II.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(9):2043-8.
2006: Maider López de Jesús; Matthias B Stope; Paschal A Oude Weernink; Yvonne Mahlke; Christof Börgermann; Viktoria N Ananaba; Christian Rimmbach; Dieter Rosskopf; Martin C Michel; Karl H Jakobs; Martina Schmidt
Cyclic AMP-dependent and Epac-mediated activation of R-Ras by G protein-coupled receptors leads to phospholipase D stimulation.
The Journal of biological chemistry 2006;281(31):21837-47.
2006: Martin C Michel; Jean J M C H de la Rosette
alpha-blocker treatment of urolithiasis.
European urology 2006;50(2):213-4.
2006: Martin C Michel; Maurits M Barendrecht; Matthias Oelke
[Anticholinergics for overactive bladder: does subtype selectivity play a role?].
Der Urologe. Ausg. A 2006;45(7):826-9.
2006: Elfaridah P Frazier; Tim Schneider; Martin C Michel
Effects of gender, age and hypertension on beta-adrenergic receptor function in rat urinary bladder.
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(4):300-9.
2006: Martin C Michel
Transient receptor potential (TRP) channels as drug targets.
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(4):271-2.
2006: Martin C Michel
An anthology from Naunyn-Schmiedeberg's Archives of Pharmacology.
Naunyn-Schmiedeberg's archives of pharmacology 2006;373(2):139.
2006: Martin C Michel; Christopher Chapple
Comparison of the cardiovascular effects of tamsulosin oral controlled absorption system (OCAS) and alfuzosin prolonged release (XL).
European urology 2006;49(3):501-8; discussion 508-9.
2006: Martin C Michel; Hiroko Okutsu; Yukiko Noguchi; Masanori Suzuki; Akiyoshi Ohtake; Hironori Yuyama; Hiroko Yanai-Inamura; Masashi Ukai; Mai Watanabe; Akiyoshi Someya; Masao Sasamata
In vivo studies on the effects of alpha1-adrenoceptor antagonists on pupil diameter and urethral tone in rabbits.
Naunyn-Schmiedeberg's archives of pharmacology 2006;372(5):346-53.
2006: Martin C Michel; Wim Vrydag
Alpha1-, alpha2- and beta-adrenoceptors in the urinary bladder, urethra and prostate.
British journal of pharmacology 2006;147 Suppl 2():S88-119.
2006: Astrid E Alewijnse; Martin C Michel
Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind?
British journal of pharmacology 2006;147(4):347-8.
2006: Marleen M van Dijk; Jean J M C H de la Rosette; Martin C Michel
Effects of alpha(1)-adrenoceptor antagonists on male sexual function.
Drugs 2006;66(3):287-301.
2005: Jan J Butter; Richard P Koopmans; Martin C Michel
A rapid and validated HPLC method to quantify sphingosine 1-phosphate in human plasma using solid-phase extraction followed by derivatization with fluorescence detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2005;824(1-2):65-70.
2005: Martin C Michel; Jean J M C H de la Rosette
Role of muscarinic receptor antagonists in urgency and nocturia.
BJU international 2005;96 Suppl 1():37-42.
2005: Martin C Michel; Jean J M C H de la Rosette; Maria Piro; Tim Schneider
Comparison of symptom severity and treatment response in patients with incontinent and continent overactive bladder.
European urology 2005;48(1):110-5.
2005: Tim Schneider; Peter Hein; Jie Bai; Martin C Michel
A role for muscarinic receptors or rho-kinase in hypertension associated rat bladder dysfunction?
The Journal of urology 2005;173(6):2178-81.
2005: Maurits M Barendrecht; Richard P Koopmans; Jean J M C H de la Rosette; Martin C Michel
Treatment of lower urinary tract symptoms suggestive of benign prostatic hyperplasia: the cardiovascular system.
BJU international 2005;95 Suppl 4():19-28.
2005: Elfaridah P Frazier; Marie-Jeanne Mathy; Stephan L M Peters; Martin C Michel
Does cyclic AMP mediate rat urinary bladder relaxation by isoproterenol?
The Journal of pharmacology and experimental therapeutics 2005;313(1):260-7.
2004: Astrid E Alewijnse; Stephan L M Peters; Martin C Michel
Cardiovascular effects of sphingosine-1-phosphate and other sphingomyelin metabolites.
British journal of pharmacology 2004;143(6):666-84.
2004: Martin C Michel; Uwe Heemann; Helmut Schumacher; Ludwig Mehlburger; Mark Goepel
Association of hypertension with symptoms of benign prostatic hyperplasia.
The Journal of urology 2004;172(4 Pt 1):1390-3.
2004: Martin C Michel; Jean J M C H de la Rosette; Maria Piro; Mark Goepel
Does concomitant stress incontinence alter the efficacy of tolterodine in patients with overactive bladder?
The Journal of urology 2004;172(2):601-4.
2004: J Hedemann; Charlotte Fetscher; Martin C Michel
Comparison of noradrenaline and lysosphingolipid-induced vasoconstriction in mouse and rat small mesenteric arteries.
Autonomic & autacoid pharmacology 2004;24(3):77-85.
2004: Martin C Michel; Stephan L M Peters
Role of serotonin and noradrenaline in stress urinary incontinence.
BJU international 2004;94 Suppl 1():23-30.
2004: Tim Schneider; Charlotte Fetscher; Susanne Krege; Martin C Michel
Signal transduction underlying carbachol-induced contraction of human urinary bladder.
The Journal of pharmacology and experimental therapeutics 2004;309(3):1148-53.
2004: Verena E Borchert; Peter Czyborra; Charlotte Fetscher; Mark Goepel; Martin C Michel
Extracts from Rhois aromatica and Solidaginis virgaurea inhibit rat and human bladder contraction.
Naunyn-Schmiedeberg's archives of pharmacology 2004;369(3):281-6.
2004: Martin C Michel; Herbert Bohner; Jürgen Köster; Rafael Schäfers; Uwe Heemann
Safety of telmisartan in patients with arterial hypertension : an open-label observational study.
Drug safety : an international journal of medical toxicology and drug experience 2004;27(5):335-44.
2004: Martin C Michel; Jean J M C H de la Rosette
Efficacy and safety of tamsulosin in the treatment of urological diseases.
Expert opinion on pharmacotherapy 2004;5(1):151-60.
2004: Marina Fleichman; Tim Schneider; Charlotte Fetscher; Martin C Michel
Signal transduction underlying carbachol-induced contraction of rat urinary bladder. II. Protein kinases.
The Journal of pharmacology and experimental therapeutics 2004;308(1):54-8.
2004: Tim Schneider; Peter Hein; Martin C Michel
Signal transduction underlying carbachol-induced contraction of rat urinary bladder. I. Phospholipases and Ca2+ sources.
The Journal of pharmacology and experimental therapeutics 2004;308(1):47-53.
2003: Richard P Koopmans; Paul A Insel; Martin C Michel
Pharmacogenetics of hypertension treatment: a structured review.
Pharmacogenetics 2003;13(12):705-13.
2003: Matthias B Stope; Christina Kunkel; Christian Kories; Martina Schmidt; Martin C Michel
Differential agonist-induced regulation of human M2 and M3 muscarinic receptors.
Biochemical pharmacology 2003;66(11):2099-105.
2003: Christian Kories; Claudia Czyborra; Charlotte Fetscher; Tim Schneider; Susanne Krege; Martin C Michel
Gender comparison of muscarinic receptor expression and function in rat and human urinary bladder: differential regulation of M2 and M3 receptors?
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(5):524-31.
2003: Christoph Altmann; Dagmar Meyer Zu Heringdorf; Dilek Böyükbas; Michael Haude; Karl H Jakobs; Martin C Michel
Sphingosylphosphorylcholine, a naturally occurring lipid mediator, inhibits human platelet function.
British journal of pharmacology 2003;138(3):435-44.
2003: Martin C Michel; Paul A Insel
Receptor gene polymorphisms: lessons on functional relevance from the beta 1-adrenoceptor.
British journal of pharmacology 2003;138(2):279-82.
2003: Christoph Altmann; Veronika Steenpass; Peter Czyborra; Peter Hein; Martin C Michel
Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine.
British journal of pharmacology 2003;138(1):261-71.
2002: Martin C Michel; Jorge D Brioni
Meeting report for the ASPET Ray Fuller Symposium: lower urinary tract disorders: physiology, pharmacology, and therapeutic approaches.
The Journal of pharmacology and experimental therapeutics 2002;303(1):431-7.
2002: Martin C Michel; Tim Schneider; Susanne Krege; Mark Goepel
Does gender or age affect the efficacy and safety of tolterodine?
The Journal of urology 2002;168(3):1027-31.
2002: Rainer Schulz; Sergej Belosjorow; Petra Gres; Johanna Jansen; Martin C Michel; Gerd Heusch
p38 MAP kinase is a mediator of ischemic preconditioning in pigs.
Cardiovascular research 2002;55(3):690-700.
2002: Stephan L M Peters; Carsten Sand; Martin C Michel; Martin Pfaffendorf; Pieter A van Zwieten
A mitogen-activated protein kinase is involved in the inotropic but not chronotropic actions of adrenoceptor agonists and endothelin-1.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(2):189-91.
2002: Charlotte Fetscher; Marina Fleichman; Martina Schmidt; Susanne Krege; Martin C Michel
M(3) muscarinic receptors mediate contraction of human urinary bladder.
British journal of pharmacology 2002;136(5):641-3.
2002: Manfrid Eltze; Thomas Grebe; Martin C Michel; Peter Czyborra; Brigitte Ullrich
Affinity profile at alpha(1)- and alpha(2)-adrenoceptor subtypes and in vitro cardiovascular actions of (+)-boldine.
European journal of pharmacology 2002;443(1-3):151-68.
2002: Martin C Michel; Angela Bischoff; Karl H Jakobs
Comparison of problem-and lecture-based pharmacology teaching.
Trends in pharmacological sciences 2002;23(4):168-70.
2002: Mark Goepel; Josef A Hoffmann; Maria Piro; Herbert Rübben; Martin C Michel
Prevalence and physician awareness of symptoms of urinary bladder dysfunction.
European urology 2002;41(3):234-9.
2002: Peter Kienbaum; Thorsten Heuter; Martin C Michel; Norbert Scherbaum; Markus Gastpar; Jürgen Peters
Sympathetic neural activation evoked by mu-receptor blockade in patients addicted to opioids is abolished by intravenous clonidine.
Anesthesiology 2002;96(2):346-51.
2002: Martin C Michel
A benefit-risk assessment of extended-release oxybutynin.
Drug safety : an international journal of medical toxicology and drug experience 2002;25(12):867-76.
2002: Peter Czyborra; Miriam Saxe; Charlotte Fetscher; Dagmar Meyer Zu Heringdorf; Stefan Herzig; Karl H Jakobs; Martin C Michel; Angela Bischoff
Transient relaxation of rat mesenteric microvessels by ceramides.
British journal of pharmacology 2002;135(2):417-26.
2001: Angela Bischoff; J Finger; Martin C Michel
Nifedipine inhibits sphinogosine-1-phosphate-induced renovascular contraction in vitro and in vivo.
Naunyn-Schmiedeberg's archives of pharmacology 2001;364(2):179-82.
2001: Rafael F Schäfers; Jens Nürnberger; A Rütz; Winfried Siffert; René R Wenzel; A Mitchell; Thomas Philipp; Martin C Michel
Haemodynamic characterization of young normotensive men carrying the 825T-allele of the G-protein beta3 subunit.
Pharmacogenetics 2001;11(6):461-70.
2001: René R Wenzel; J Rüthemann; H Bruck; Rafael F Schäfers; Martin C Michel; Thomas Philipp
Endothelin-A receptor antagonist inhibits angiotensin II and noradrenaline in man.
British journal of clinical pharmacology 2001;52(2):151-7.
2001: Martin C Michel; HU Bressel; Mark Goepel; H Rübben
A 6-month large-scale study into the safety of tamsulosin.
British journal of clinical pharmacology 2001;51(6):609-14.
2001: Manfrid Eltze; Rainer Boer; Martin C Michel; Peter Hein; R Testa; Wolf-Rüdiger Ulrich; N Kolassa; K H Sanders
In vitro and in vivo uroselectivity of B8805-033, an antagonist with high affinity at prostatic alpha1A- vs. alpha1B- and alpha1D-adrenoceptors.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(6):649-62.
2001: Angela Bischoff; Dagmar Meyer Zu Heringdorf; Karl H Jakobs; Martin C Michel
Lysosphingolipid receptor-mediated diuresis and natriuresis in anaesthetized rats.
British journal of pharmacology 2001;132(8):1925-33.
2001: Angela Bischoff; K Püttmann; A Kötting; C Moser; A Buschauer; Martin C Michel
Limited signal transduction repertoire of human Y(5) neuropeptide Y receptors expressed in HEC-1B cells.
Peptides 2001;22(3):387-94.
2001: Martin C Michel; Y Li; G Heusch
Mitogen-activated protein kinases in the heart.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(3):245-66.
2001: Peter Kienbaum; Thorsten Heuter; Martin C Michel; Norbert Scherbaum; Markus Gastpar; Jürgen Peters
Chronic mu-opioid receptor stimulation in humans decreases muscle sympathetic nerve activity.
Circulation 2001;103(6):850-5.
2001: Peter Kienbaum; Thorsten Heuter; Goran Pavlakovic; Martin C Michel; Jürgen Peters
S(+)-ketamine increases muscle sympathetic activity and maintains the neural response to hypotensive challenges in humans.
Anesthesiology 2001;94(2):252-8.
2001: Charlotte Fetscher; H Chen; Rafael F Schäfers; G Wambach; G Heusch; Martin C Michel
Modulation of noradrenaline-induced microvascular constriction by protein kinase inhibitors.
Naunyn-Schmiedeberg's archives of pharmacology 2001;363(1):57-65.
2001: Martin C Michel; H G Neumann; Ludwig Mehlburger; Helmut Schumacher; Mark Goepel
Does the time of administration (morning or evening) affect the tolerability or efficacy of tamsulosin?
BJU international 2001;87(1):31-4.
2000: Martin C Michel; R F Schafers; Mark Goepel
Alpha-blockers and lower urinary tract function: more than smooth muscle relaxation?
BJU international 2000;86 Suppl 2():23-8; discussion 28-30.
2000: Matthias Behrends; Rainer Schulz; Heiner Post; A Alexandrov; Sergej Belosjorow; Martin C Michel; Gerd Heusch
Inconsistent relation of MAPK activation to infarct size reduction by ischemic preconditioning in pigs.
American journal of physiology. Heart and circulatory physiology 2000;279(3):H1111-9.
2000: Angela Bischoff; Peter Czyborra; Dagmar Meyer Zu Heringdorf; Karl H Jakobs; Martin C Michel
Sphingosine-1-phosphate reduces rat renal and mesenteric blood flow in vivo in a pertussis toxin-sensitive manner.
British journal of pharmacology 2000;130(8):1878-83.
2000: Angela Bischoff; Peter Czyborra; Charlotte Fetscher; Dagmar Meyer Zu Heringdorf; Karl H Jakobs; Martin C Michel
Sphingosine-1-phosphate and sphingosylphosphorylcholine constrict renal and mesenteric microvessels in vitro.
British journal of pharmacology 2000;130(8):1871-7.
2000: Gerd Heusch; H Post; Martin C Michel; M Kelm; Rainer Schulz
Endogenous nitric oxide and myocardial adaptation to ischemia.
Circulation research 2000;87(2):146-52.
2000: S Keffel; A Alexandrov; Mark Goepel; Martin C Michel
alpha(1)-adrenoceptor subtypes differentially couple to growth promotion and inhibition in Chinese hamster ovary cells.
Biochemical and biophysical research communications 2000;272(3):906-11.
2000: Martin C Michel; Ludwig Mehlburger; Helmut Schumacher; HU Bressel; Mark Goepel
Effect of diabetes on lower urinary tract symptoms in patients with benign prostatic hyperplasia.
The Journal of urology 2000;163(6):1725-9.
2000: Peter Kienbaum; Norbert Scherbaum; N Thürauf; Martin C Michel; Markus Gastpar; Jürgen Peters
Acute detoxification of opioid-addicted patients with naloxone during propofol or methohexital anesthesia: a comparison of withdrawal symptoms, neuroendocrine, metabolic, and cardiovascular patterns.
Critical care medicine 2000;28(4):969-76.
2000: Angela Bischoff; Martin C Michel
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion.
Canadian journal of physiology and pharmacology 2000;78(2):93-9.
2000: Angela Bischoff; A Gerbracht; Martin C Michel
Gender and hypertension interact to regulate neuropeptide Y receptor responsiveness.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(2):173-80.
2000: Martin C Michel; Mark Goepel
Treatment satisfaction of patients with lower urinary tract symptoms: randomised controlled trials vs. real life practice.
European urology 2000;38 Suppl 1():40-7.
2000: Peter Kienbaum; Thorsten Heuter; Martin C Michel; Jürgen Peters
Racemic ketamine decreases muscle sympathetic activity but maintains the neural response to hypotensive challenges in humans.
Anesthesiology 2000;92(1):94-101.
1999: S Keffel; M Schmidt; Angela Bischoff; Martin C Michel
Neuropeptide-Y stimulation of extracellular signal-regulated kinases in human erythroleukemia cells.
The Journal of pharmacology and experimental therapeutics 1999;291(3):1172-8.
1999: Angela Bischoff; A Neumann; A Dendorfer; Martin C Michel
Is bradykinin a mediator of renal neuropeptide Y effects?
Pflügers Archiv : European journal of physiology 1999;438(6):797-803.
1999: Martin C Michel; C Plogmann; Thomas Philipp; Otto-Erich Brodde
Functional correlates of alpha(2A)-adrenoceptor gene polymorphism in the HANE study.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 1999;14(11):2657-63.
1999: V Limmroth; A Bischoff; C Fetscher; D Wermelskirchen; H Diener; Martin C Michel
Effects of alniditan on neurogenic oedema in the rat dura mater and on contraction of rat basilar artery.
European journal of pharmacology 1999;382(2):103-9.
1999: A Alexandrov; S Keffel; Mark Goepel; Martin C Michel
Differential regulation of 46 and 54 kDa jun N-terminal kinases and p38 mitogen-activated protein kinase by human alpha(1A)-adrenoceptors expressed in Rat-1 cells.
Biochemical and biophysical research communications 1999;261(2):372-6.
1999: M Yang; J Ruan; M Voller; J Schalken; Martin C Michel
Differential regulation of human alpha1-adrenoceptor subtypes.
Naunyn-Schmiedeberg's archives of pharmacology 1999;359(6):439-46.
1999: Rafael F Schäfers; Jens Nürnberger; B Herrmann; René R Wenzel; Thomas Philipp; Martin C Michel
Adrenoceptors mediating the cardiovascular and metabolic effects of alpha-methylnoradrenaline in humans.
The Journal of pharmacology and experimental therapeutics 1999;289(2):918-25.
1999: Jürgen F Heubach; I Trebess; Erich Wettwer; Herbert M Himmel; Martin C Michel; Alberto J Kaumann; Walter J Koch; Sian E Harding; Ursula Ravens
L-type calcium current and contractility in ventricular myocytes from mice overexpressing the cardiac beta 2-adrenoceptor.
Cardiovascular research 1999;42(1):173-82.
1999: Herbert Sperling; Martin C Michel; Herbert Rübben
[Sildenafil (Viagra). Tolerance, contraindications, drug interactions].
Der Urologe. Ausg. A 1999;38(2):124-7.
1999: Herbert Sperling; Martin C Michel
[Sildenafil].
Deutsche medizinische Wochenschrift (1946) 1999;124(6):151-3.
1999: Rafael F Schäfers; B Fokuhl; A Wasmuth; H Schumacher; K Taguchi; C de Mey; Thomas Philipp; Martin C Michel
Differential vascular alpha1-adrenoceptor antagonism by tamsulosin and terazosin.
British journal of clinical pharmacology 1999;47(1):67-74.
1998: A Alexandrov; S Keffel; Mark Goepel; Martin C Michel
Stimulation of alpha1A-adrenoceptors in Rat-1 cells inhibits extracellular signal-regulated kinase by activating p38 mitogen-activated protein kinase.
Molecular pharmacology 1998;54(5):755-60.
1998: Angela Bischoff; W Rascher; Martin C Michel
Bradykinin may be involved in neuropeptide Y-induced diuresis, natriuresis, and calciuresis.
The American journal of physiology 1998;275(4 Pt 2):F502-9.
1998: Martin C Michel; Ludwig Mehlburger; HU Bressel; Helmut Schumacher; Rafael F Schäfers; Mark Goepel
Tamsulosin treatment of 19,365 patients with lower urinary tract symptoms: does co-morbidity alter tolerability?
The Journal of urology 1998;160(3 Pt 1):784-91.
1998: M Yang; J Reese; S Cotecchia; Martin C Michel
Murine alpha1-adrenoceptor subtypes. I. Radioligand binding studies.
The Journal of pharmacology and experimental therapeutics 1998;286(2):841-7.
1998: Angela Bischoff; V Limmroth; Martin C Michel
Indomethacin inhibits the natriuretic effects of neuropeptide Y in anesthetized rats.
The Journal of pharmacology and experimental therapeutics 1998;286(2):704-8.
1998: M Yang; R Büscher; K Taguchi; B Grübbel; P A Insel; Martin C Michel
Protein kinase C does not mediate phenylephrine-induced down-regulation of Madin-Darby canine kidney cell alpha-1B adrenoceptors.
The Journal of pharmacology and experimental therapeutics 1998;286(1):36-43.
1998: Peter Kienbaum; N Thürauf; Martin C Michel; Norbert Scherbaum; Markus Gastpar; Jürgen Peters
Profound increase in epinephrine concentration in plasma and cardiovascular stimulation after mu-opioid receptor blockade in opioid-addicted patients during barbiturate-induced anesthesia for acute detoxification.
Anesthesiology 1998;88(5):1154-61.
1998: Rafael F Schäfers; Martin C Michel
[Terazosin].
Deutsche medizinische Wochenschrift (1946) 1998;123(15):459-60.
1998: Andreas Kribben; Stefan Herget-Rosenthal; Bettina Lange; Martin C Michel; Thomas Philipp
Stimulation of mitogen activated protein kinase and cellular proliferation in renal proximal tubular cells.
Renal failure 1998;20(2):229-34.
1998: Martin C Michel; Annette G Beck-Sickinger; H Cox; H N Doods; Herbert Herzog; D Larhammar; R Quirion; T Schwartz; T Westfall
XVI. International Union of Pharmacology recommendations for the nomenclature of neuropeptide Y, peptide YY, and pancreatic polypeptide receptors.
Pharmacological reviews 1998;50(1):143-50.
1998: Stephan L M Peters; HD Batink; Martin C Michel; Martin Pfaffendorf; Pieter A van Zwieten
Possible mechanism of the negative inotropic effect of alpha1-adrenoceptor agonists in rat isolated left atria after exposure to free radicals.
British journal of pharmacology 1998;123(5):952-8.
1998: J Zwaveling; HD Batink; K Taguchi; J de Jong; Martin C Michel; Martin Pfaffendorf; A van Zwieten
Thyroid status affects the rat cardiac beta-adrenoceptor system transiently and time-dependently.
Journal of autonomic pharmacology 1998;18(1):1-11.
1998: Martin C Michel; Mark Goepel
Differential alpha1-adrenoceptor labeling by [3H]prazosin and [3H]tamsulosin.
European journal of pharmacology 1998;342(1):85-92.
1998: Martin C Michel; HU Bressel; Ludwig Mehlburger; Mark Goepel
Tamsulosin: real life clinical experience in 19,365 patients.
European urology 1998;34 Suppl 2():37-45.
1998: K Taguchi; Rafael F Schäfers; Martin C Michel
Radioreceptor assay analysis of tamsulosin and terazosin pharmacokinetics.
British journal of clinical pharmacology 1998;45(1):49-55.
1998: Martin C Michel; K Taguchi; R S Schäfers; TJ Williams; DE Clarke; Anthony P D W Ford
Alpha 1-adrenoceptor subtypes in the human cardiovascular and urogenital systems.
Advances in pharmacology (San Diego, Calif.) 1998;42():394-8.
1997: Andreas Kribben; Stefan Herget-Rosenthal; Bettina Lange; Wilhelm Erdbrügger; Thomas Philipp; Martin C Michel
Alpha2-adrenoceptors in opossum kidney cells couple to stimulation of mitogen-activated protein kinase independently of adenylyl cyclase inhibition.
Naunyn-Schmiedeberg's archives of pharmacology 1997;356(2):225-32.
1997: H Chen; Angela Bischoff; Rafael F Schäfers; G Wambach; Thomas Philipp; Martin C Michel
Vasoconstriction of rat renal interlobar arteries by noradrenaline and neuropeptide Y.
Journal of autonomic pharmacology 1997;17(3):137-46.
1997: M Yang; F Verfürth; R Büscher; Martin C Michel
Is alpha1D-adrenoceptor protein detectable in rat tissues?
Naunyn-Schmiedeberg's archives of pharmacology 1997;355(4):438-46.
1997: Angela Bischoff; P Avramidis; Wilhelm Erdbrügger; K Münter; Martin C Michel
Receptor subtypes Y1 and Y5 are involved in the renal effects of neuropeptide Y.
British journal of pharmacology 1997;120(7):1335-43.
1997: Wilhelm Erdbrügger; J Keffel; M Knocks; T Otto; T Philipp; Martin C Michel
Protein kinase C isoenzymes in rat and human cardiovascular tissues.
British journal of pharmacology 1997;120(2):177-86.
1997: K Taguchi; M Saitoh; S Sato; M Asano; Martin C Michel
Effects of tamsulosin metabolites at alpha-1 adrenoceptor subtypes.
The Journal of pharmacology and experimental therapeutics 1997;280(1):1-5.
1996: D Grandt; M Schimiczek; W Rascher; F Feth; John E Shively; T D Lee; M T Davis; Joseph R Reeve; Martin C Michel
Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors.
Regulatory peptides 1996;67(1):33-7.
1996: Angela Bischoff; Wilhelm Erdbrügger; J Smits; Martin C Michel
Neuropeptide Y-enhanced diuresis and natriuresis in anaesthetized rats is independent of renal blood flow reduction.
The Journal of physiology 1996;495 ( Pt 2)():525-34.
1996: Martin C Michel; S Kaldenberg-Stasch; Thomas Wieland
Cytoskeletal inhibitors impair Ca2+ elevations via neuropeptide Y and other Gi-coupled receptors.
European journal of pharmacology 1996;309(1):87-94.
1996: H Chen; C Fetscher; Rafael F Schäfers; G Wambach; Thomas Philipp; Martin C Michel
Effects of noradrenaline and neuropeptide Y on rat mesenteric microvessel contraction.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(3):314-23.
1996: Dagmar Meyer Zu Heringdorf; K Liedel; S Kaldenberg-Stasch; Martin C Michel; Karl H Jakobs; Thomas Wieland
Translocation of microfilament-associated inhibitory guanine-nucleotide-binding proteins to the plasma membrane in myeloid differentiated human leukemia (HL-60) cells.
European journal of biochemistry / FEBS 1996;235(3):670-6.
1996: Martin C Michel; L C Rump
alpha-Adrenergic regulation of human renal function.
Fundamental & clinical pharmacology 1996;10(6):493-503.
1995: Martina Schmidt; C Bienek; Chris J van Koppen; Martin C Michel; Karl H Jakobs
Differential calcium signalling by m2 and m3 muscarinic acetylcholine receptors in a single cell type.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(5):469-76.
1995: Wilhelm Erdbrügger; P Strohm; Martin C Michel
Is the glycogen synthase analogue C1-peptide a suitable fluorescent substrate for routine measurements of protein kinase C?
Cellular signalling 1995;7(6):635-42.
1995: Martin C Michel; B Kenny; Debra Anne Schwinn
Classification of alpha 1-adrenoceptor subtypes.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(1):1-10.
1995: Wilhelm Erdbrügger; M Raulf; T Otto; Martin C Michel
Does [3H]2-methoxy-idazoxan (RX 821002) detect more alpha-2-adrenoceptor agonist high-affinity sites than [3H]rauwolscine? A comparison of nine tissues and cell lines.
The Journal of pharmacology and experimental therapeutics 1995;273(3):1287-94.
1995: Martin C Michel; W Rascher
Neuropeptide Y: a possible role in hypertension?
Journal of hypertension 1995;13(4):385-95.
1995: Martin C Michel; K Lewejohann; W Farke; Angela Bischoff; F Feth; Wolfgang Rascher
Regulation of NPY/NPY Y1 receptor/G protein system in rat brain cortex.
The American journal of physiology 1995;268(1 Pt 2):R192-200.
1994: R Büscher; Wilhelm Erdbrügger; Thomas Philipp; Otto-Erich Brodde; Martin C Michel
Comparison of alpha 1A- and alpha 1B-adrenoceptor coupling to inositol phosphate formation in rat kidney.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(6):592-8.
1994: D Grandt; F Feth; W Rascher; Joseph R Reeve; E Schlicker; M Schimiczek; Peter Layer; Harald Goebell; Viktor E Eysselein; Martin C Michel
[Pro34]peptide YY is a Y1-selective agonist at peptide YY/neuropeptide Y receptors.
European journal of pharmacology 1994;269(2):127-32.
1994: Martin C Michel; J Knapp; H Ratjen
Sensitization by dexamethasone of lymphocyte cyclic AMP formation: evidence for increased function of the adenylyl cyclase catalyst.
British journal of pharmacology 1994;113(1):240-6.
1994: Martin C Michel; P A Insel
Comparison of cloned and pharmacologically defined rat tissue alpha 1-adrenoceptor subtypes.
Naunyn-Schmiedeberg's archives of pharmacology 1994;350(2):136-42.
1994: Martin C Michel; W Farke; Wilhelm Erdbrügger; Thomas Philipp; Otto-Erich Brodde
Ontogenesis of sympathetic responsiveness in spontaneously hypertensive rats. II. Renal G proteins in male and female rats.
Hypertension 1994;23(5):653-8.
1994: Martin C Michel; G Hanft; G Gross
Functional studies on alpha 1-adrenoceptor subtypes mediating inotropic effects in rat right ventricle.
British journal of pharmacology 1994;111(2):539-46.
1994: Martin C Michel; G Hanft; G Gross
Radioligand binding studies of alpha 1-adrenoceptor subtypes in rat heart.
British journal of pharmacology 1994;111(2):533-8.
1993: Martin C Michel; J Kerker; Theresa A Branchek; Carlos Forray
Selective irreversible binding of chloroethylclonidine at alpha 1- and alpha 2-adrenoceptor subtypes.
Molecular pharmacology 1993;44(6):1165-70.
1993: Martin C Michel; R Büscher; J Kerker; H Kraneis; Wilhelm Erdbrügger; Otto-Erich Brodde
Alpha 1-adrenoceptor subtype affinities of drugs for the treatment of prostatic hypertrophy. Evidence for heterogeneity of chloroethylclonidine-resistant rat renal alpha 1-adrenoceptor.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(4):385-95.
1993: Martin C Michel; F Siepmann; R Büscher; Thomas Philipp; Otto-Erich Brodde
Ontogenesis of sympathetic responsiveness in spontaneously hypertensive rats. I. Renal alpha 1-, alpha 2-, and beta-adrenergic receptors and their signaling.
Hypertension 1993;22(2):169-77.
1993: S Petrasch; L J van Tits; H J Motulsky; Otto-Erich Brodde; Martin C Michel
Effects of ketotifen on human lymphocytes in vitro and in vivo.
Arzneimittel-Forschung 1993;43(8):904-8.
1993: Kirk U Knowlton; Martin C Michel; M Itani; H E Shubeita; K Ishihara; Joan Heller Brown; Kenneth R Chien
The alpha 1A-adrenergic receptor subtype mediates biochemical, molecular, and morphologic features of cultured myocardial cell hypertrophy.
The Journal of biological chemistry 1993;268(21):15374-80.
1993: M B Michel-Reher; G Gross; J R Jasper; D Bernstein; T Olbricht; O E Brodde; Martin C Michel
Tissue- and subunit-specific regulation of G-protein expression by hypo- and hyperthyroidism.
Biochemical pharmacology 1993;45(7):1417-23.
1993: Martin C Michel; Otto-Erich Brodde; Paul Insel
Are cardiac G-proteins altered in rat models of hypertension?
Journal of hypertension 1993;11(4):355-63.
1993: Hans Zerkowski; A Broede; K Kunde; S Hillemann; E Schäfer; M Vogelsang; Martin C Michel; Otto-Erich Brodde
Comparison of the positive inotropic effects of serotonin, histamine, angiotensin II, endothelin and isoprenaline in the isolated human right atrium.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(4):347-52.
1993: D R Murray; S M Polizzi; T Harris; N Wilson; Martin C Michel; Alan S Maisel
Prolonged isoproterenol treatment alters immunoregulatory cell traffic and function in the rat.
Brain, behavior, and immunity 1993;7(1):47-62.
1993: Martin C Michel; R Büscher; Thomas Philipp; Otto-Erich Brodde
Alpha 1A and alpha 1B-adrenoceptors enhance inositol phosphate generation in rat renal cortex.
Naunyn-Schmiedeberg's archives of pharmacology 1993;347(2):180-5.
1993: Otto-Erich Brodde; I Klusmann; M Wojcik; A J Man in't Veld; F Boomsma; Martin C Michel
Lack of desensitization of alpha- and beta-adrenoceptor function during chronic treatment of healthy volunteers with ibopamine, an orally active dopamine receptor agonist.
European journal of clinical pharmacology 1993;44(3):283-6.
1992: Otto-Erich Brodde; Martin C Michel
Adrenergic receptors and their signal transduction mechanisms in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1992;10(7):S133-45.
1992: Martin C Michel; Paul Ernsberger
Keeping an eye on the I site: imidazoline-preferring receptors.
Trends in pharmacological sciences 1992;13(10):369-70.
1992: Martin C Michel; W Gaida; Annette G Beck-Sickinger; H A Wieland; Henri Doods; H Dürr; G Jung; G Schnorrenberg
Further characterization of neuropeptide Y receptor subtypes using centrally truncated analogs of neuropeptide Y: evidence for subtype-differentiating effects on affinity and intrinsic efficacy.
Molecular pharmacology 1992;42(4):642-8.
1992: Otto-Erich Brodde; S Petrasch; H J Bauch; AE Daul; M Gnadt; D Oefler; Martin C Michel
Terbutaline-induced desensitization of beta 2-adrenoceptor in vivo function in humans: attenuation by ketotifen.
Journal of cardiovascular pharmacology 1992;20(3):434-9.
1992: C A Jackson; Martin C Michel; Paul Insel
Expression of renal alpha 1-adrenergic receptor subtypes in established hypertension.
Journal of cardiovascular pharmacology 1992;19(6):857-62.
1992: Martin C Michel; T Philipp; Otto-Erich Brodde
Alpha- and beta-adrenoceptors in hypertension: molecular biology and pharmacological studies.
Pharmacology & toxicology 1992;70(6 Pt 2):S1-10.
1992: Martin C Michel; F Feth; M Stieneker; W Rascher
NPY and carbachol raise Ca2+ in SK-N-MC cells by three different mechanisms. Evidence for inositol phosphate-independent Ca2+ mobilization by NPY.
Naunyn-Schmiedeberg's archives of pharmacology 1992;345(4):370-4.
1992: Martin C Michel; F Feth; W Rascher
NPY-stimulated Ca2+ mobilization in SK-N-MC cells is enhanced after isoproterenol treatment.
The American journal of physiology 1992;262(4 Pt 1):E383-8.
1992: Martin C Michel; S Jäger; R Casto; R Rettig; C Graf; M Printz; P A Insel; Thomas Philipp; Otto-Erich Brodde
On the role of renal alpha-adrenergic receptors in spontaneously hypertensive rats.
Hypertension 1992;19(4):365-70.
1992: Otto-Erich Brodde; H J Hundhausen; Hans Zerkowski; Martin C Michel
Lack of effect of chronic calcium antagonist treatment on beta 1- and beta 2-adrenoceptors in right atria from patients with or without heart failure.
British journal of clinical pharmacology 1992;33(3):269-74.
1992: L Brown; N M Deighton; S Bals; W Söhlmann; Hans Zerkowski; Martin C Michel; Otto-Erich Brodde
Spare receptors for beta-adrenoceptor-mediated positive inotropic effects of catecholamines in the human heart.
Journal of cardiovascular pharmacology 1992;19(2):222-32.
1992: Otto-Erich Brodde; AE Daul; Martin C Michel; Hans Zerkowski
[Importance of beta 2-adrenergic receptors in heart failure].
Zeitschrift für Kardiologie 1992;81 Suppl 4():71-8.
1992: Otto-Erich Brodde; A Broede; AE Daul; K Kunde; Martin C Michel
Receptor systems in the non-failing human heart.
Basic research in cardiology 1992;87 Suppl 1():1-14.
1991: J R Jasper; Martin C Michel; Paul Insel
Partial agonistic activity of two irreversible beta-adrenergic receptor ligands, bromoacetylated derivatives of alprenolol and pindolol.
Biochemical pharmacology 1991;42 Suppl():S212-4.
1991: Alan S Maisel; D Murray; M Lotz; A Rearden; M Irwin; Martin C Michel
Propranolol treatment affects parameters of human immunity.
Immunopharmacology 1991;22(3):157-64.
1991: Martin C Michel
Receptors for neuropeptide Y: multiple subtypes and multiple second messengers.
Trends in pharmacological sciences 1991;12(10):389-94.
1991: Alan S Maisel; D Murray; S Polizzi; H J Motulsky; Otto-Erich Brodde; L J van Tits; Martin C Michel
Does verapamil act as an immunomodulatory drug in vivo?
Immunopharmacology 1991;22(2):85-91.
1991: Martin C Michel; M Klüppel; Thomas Philipp; Otto-Erich Brodde
Does treatment with beta-adrenoceptor antagonists in vivo alter human adenylate cyclase responsiveness in vitro?
British journal of clinical pharmacology 1991;32(1):105-9.
1991: Martin C Michel; G Mindermann; AE Daul; Otto-Erich Brodde
Effects of antihypertensive therapy on human alpha- and beta-adrenoceptors.
Journal of hypertension 1991;9(7):601-6.
1991: L J van Tits; Martin C Michel; H J Motulsky; Alan S Maisel; Otto-Erich Brodde
Cyclic AMP counteracts mitogen-induced inositol phosphate generation and increases in intracellular Ca2+ concentrations in human lymphocytes.
British journal of pharmacology 1991;103(2):1288-94.
1990: Alan S Maisel; T Harris; C A Rearden; Martin C Michel
Beta-adrenergic receptors in lymphocyte subsets after exercise. Alterations in normal individuals and patients with congestive heart failure.
Circulation 1990;82(6):2003-10.
1990: S Motomura; N M Deighton; Hans Zerkowski; N Doetsch; Martin C Michel; Otto-Erich Brodde
Chronic beta 1-adrenoceptor antagonist treatment sensitizes beta 2-adrenoceptors, but desensitizes M2-muscarinic receptors in the human right atrium.
British journal of pharmacology 1990;101(2):363-9.
1990: Martin C Michel; Otto-Erich Brodde; P A Insel
Peripheral adrenergic receptors in hypertension.
Hypertension 1990;16(2):107-20.
1990: N A Scott; Martin C Michel; J H Boublik; Jean E Rivier; S Motomura; R L Crum; M Landon; M R Brown
Distinction of NPY receptors in vitro and in vivo. II. Differential effects of NPY and NPY-(18-36).
The American journal of physiology 1990;259(1 Pt 2):H174-80.
1990: Martin C Michel; E Schlicker; K Fink; J H Boublik; M Göthert; R N Willette; R N Daly; J P Hieble; Jean E Rivier; H J Motulsky
Distinction of NPY receptors in vitro and in vivo. I. NPY-(18-36) discriminates NPY receptor subtypes in vitro.
The American journal of physiology 1990;259(1 Pt 1):E131-9.
1990: L J van Tits; AE Daul; H J Bauch; H Grosse-Wilde; M Happel; Martin C Michel; Otto-Erich Brodde
Effects of insulin-induced hypoglycemia on beta 2-adrenoceptor density and proliferative responses of human lymphocytes.
The Journal of clinical endocrinology and metabolism 1990;71(1):187-92.
1990: Alan S Maisel; Martin C Michel; Paul Insel; C Ennis; Michael G Ziegler; C Phillips
Pertussis toxin treatment of whole blood. A novel approach to assess G protein function in congestive heart failure.
Circulation 1990;81(4):1198-204.
1990: Alan S Maisel; Kirk U Knowlton; P Fowler; A Rearden; Michael G Ziegler; H J Motulsky; Paul Insel; Martin C Michel
Adrenergic control of circulating lymphocyte subpopulations. Effects of congestive heart failure, dynamic exercise, and terbutaline treatment.
The Journal of clinical investigation 1990;85(2):462-7.
1990: Alan S Maisel; Martin C Michel
Beta-adrenoceptor control of immune function in congestive heart failure.
British journal of clinical pharmacology 1990;30 Suppl 1():49S-53S.
1990: J R Jasper; Martin C Michel; Paul Insel
The beta-adrenoceptor antagonist carteolol and its metabolite 8-hydroxycarteolol have different intrinsic sympathomimetic activities.
British journal of clinical pharmacology 1990;30 Suppl 1():109S-111S.
1990: L J Van Tits; Martin C Michel; H Grosse-Wilde; M Happel; F W Eigler; A Soliman; Otto-Erich Brodde
Catecholamines increase lymphocyte beta 2-adrenergic receptors via a beta 2-adrenergic, spleen-dependent process.
The American journal of physiology 1990;258(1 Pt 1):E191-202.
1990: Martin C Michel; John W Regan; M A Gerhardt; Richard Neubig; Paul Insel; H J Motulsky
Nonadrenergic [3H]idazoxan binding sites are physically distinct from alpha 2-adrenergic receptors.
Molecular pharmacology 1990;37(1):65-8.
1990: Otto-Erich Brodde; A Daul; Martin C Michel
Subtype-selective modulation of human beta 1- and beta 2-adrenoceptor function by beta-adrenoceptor agonists and antagonists.
Clinical physiology and biochemistry 1990;8 Suppl 2():11-7.
1990: J R Jasper; Martin C Michel; Paul Insel
Amplification of cyclic AMP generation reveals agonistic effects of certain beta-adrenergic antagonists.
Molecular pharmacology 1990;37(1):44-9.
1989: S Motomura; B Schnepel; U Seher; Martin C Michel; Otto-Erich Brodde
Properties of alpha 2-adrenoceptors in human myometrium and kidney: similarities with human platelets, but differences in the rat kidney.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(6):S50-1.
1989: Martin C Michel; S C Wirth; Hans Zerkowski; A S Maisel; H J Motulsky
Lack of inotropic effects of neuropeptide Y in human myocardium.
Journal of cardiovascular pharmacology 1989;14(6):919-22.
1989: Alan S Maisel; P Fowler; A Rearden; H J Motulsky; Martin C Michel
A new method for isolation of human lymphocyte subsets reveals differential regulation of beta-adrenergic receptors by terbutaline treatment.
Clinical pharmacology and therapeutics 1989;46(4):429-39.
1989: Alan S Maisel; C Phillips; Martin C Michel; Michael G Ziegler; Steven M Carter
Regulation of cardiac beta-adrenergic receptors by captopril. Implications for congestive heart failure.
Circulation 1989;80(3):669-75.
1989: Otto-Erich Brodde; Hans Zerkowski; N Doetsch; S Motomura; M Khamssi; Martin C Michel
Myocardial beta-adrenoceptor changes in heart failure: concomitant reduction in beta 1- and beta 2-adrenoceptor function related to the degree of heart failure in patients with mitral valve disease.
Journal of the American College of Cardiology 1989;14(2):323-31.
1989: Martin C Michel; L F Brass; A Williams; G M Bokoch; V J LaMorte; H J Motulsky
Alpha 2-adrenergic receptor stimulation mobilizes intracellular Ca2+ in human erythroleukemia cells.
The Journal of biological chemistry 1989;264(9):4986-91.
1989: Martin C Michel; Otto-Erich Brodde; B Schnepel; J Behrendt; R Tschada; H J Motulsky; Paul Insel
[3H]idazoxan and some other alpha 2-adrenergic drugs also bind with high affinity to a nonadrenergic site.
Molecular pharmacology 1989;35(3):324-30.
1989: Martin C Michel; Paul Insel; Otto-Erich Brodde
Renal alpha-adrenergic receptor alterations: a cause of essential hypertension?
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1989;3(2):139-44.
1989: A S Maisel; N A Scott; H J Motulsky; Martin C Michel; J H Boublik; Jean E Rivier; M Ziegler; R S Allen; M R Brown
Elevation of plasma neuropeptide Y levels in congestive heart failure.
The American journal of medicine 1989;86(1):43-8.
1989: Martin C Michel; Otto-Erich Brodde
Lymphocyte adenylate cyclase activity in immunosuppressed patients.
European journal of clinical pharmacology 1989;37(1):41-3.
1989: Martin C Michel; A Pingsmann; M Nohlen; U Siekmann; Otto-Erich Brodde
Decreased myometrial beta-adrenoceptors in women receiving beta 2-adrenergic tocolytic therapy: correlation with lymphocyte beta-adrenoceptors.
Clinical pharmacology and therapeutics 1989;45(1):1-8.
1989: Alan S Maisel; Martin C Michel
Beta-adrenergic receptors in congestive heart failure: present knowledge and future directions.
Cardiology 1989;76(5):338-46.
1989: H J Motulsky; Martin C Michel
Interaction between alpha 2-adrenergic and NPY receptor pathways in human erythroleukemia cells.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11 Suppl 1():281-6.
1988: H J Motulsky; Martin C Michel
Neuropeptide Y mobilizes Ca2+ and inhibits adenylate cyclase in human erythroleukemia cells.
The American journal of physiology 1988;255(6 Pt 1):E880-5.
1988: J R Jasper; Martin C Michel; Paul Insel
Molecular mechanism of beta-adrenergic receptor blockers with intrinsic sympathomimetic activity.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(13):2891-4.
1988: Martin C Michel; A Pingsmann; J J Beckeringh; Hans Zerkowski; N Doetsch; Otto-Erich Brodde
Selective regulation of beta 1- and beta 2-adrenoceptors in the human heart by chronic beta-adrenoceptor antagonist treatment.
British journal of pharmacology 1988;94(3):685-92.
1988: Otto-Erich Brodde; A Daul; A Wellstein; D Palm; Martin C Michel; J J Beckeringh
Differentiation of beta 1- and beta 2-adrenoceptor-mediated effects in humans.
The American journal of physiology 1988;254(2 Pt 2):H199-206.
1987: A E Daul; X L Wang; Martin C Michel; Otto-Erich Brodde
Arterial hypotension in chronic hemodialyzed patients.
Kidney international 1987;32(5):728-35.
1987: Martin C Michel; A Rother; Christoph Hiemke; R Ghraf
Inhibition of synaptosomal high-affinity uptake of dopamine and serotonin by estrogen agonists and antagonists.
Biochemical pharmacology 1987;36(19):3175-80.
1987: K Ikezono; Martin C Michel; Hans Zerkowski; J J Beckeringh; Otto-Erich Brodde
The role of cyclic AMP in the positive inotropic effect mediated by beta 1- and beta 2-adrenoceptors in isolated human right atrium.
Naunyn-Schmiedeberg's archives of pharmacology 1987;335(5):561-6.
1987: K Ikezono; Hans Zerkowski; J J Beckeringh; Martin C Michel; Otto-Erich Brodde
Beta-2 adrenoceptor-mediated relaxation of the isolated human saphenous vein.
The Journal of pharmacology and experimental therapeutics 1987;241(1):294-9.
1986: Martin C Michel; J J Beckeringh; K Ikezono; R Kretsch; Otto-Erich Brodde
Lymphocyte beta 2-adrenoceptors mirror precisely beta 2-adrenoceptor, but poorly beta 1-adrenoceptor changes in the human heart.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1986;4(6):S215-8.