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Alan Michelson

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Andrew L Frelinger; Michael Lampa; Ronald D Lee; Darcy J Mulford; Anu Nigam; Sai Nudurupati; Jingtao Wu; Marc R Barnard; Deepak L Bhatt; Julie K Brooks; Alan D Michelson
Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function.
Michelle A Berny-Lang; Joseph A Jakubowski; Alan D Michelson; Atsuhiro Sugidachi; Marc R Barnard; Andrew L Frelinger
P2Y12 Receptor Blockade Augments Glycoprotein IIb-IIIa Antagonist Inhibition of Platelet Activation, Aggregation, and Procoagulant Activity.
H Chang; E J Dix; Marc R Barnard; Y F Li; Alan D Michelson; G E Wright; I B Yanachkov; Andrew L Frelinger
Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.

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2013: Andrew L Frelinger; Michael Lampa; Ronald D Lee; Darcy J Mulford; Anu Nigam; Sai Nudurupati; Jingtao Wu; Marc R Barnard; Deepak L Bhatt; Julie K Brooks; Alan D Michelson
Clopidogrel pharmacokinetics and pharmacodynamics vary widely despite exclusion or control of polymorphisms (CYP2C19, ABCB1, PON1), noncompliance, diet, smoking, co-medications (including proton pump inhibitors), and pre-existent variability in platelet function.
Journal of the American College of Cardiology 2013;61(8):872-9.
2013: Michelle A Berny-Lang; Joseph A Jakubowski; Alan D Michelson; Atsuhiro Sugidachi; Marc R Barnard; Andrew L Frelinger
P2Y12 Receptor Blockade Augments Glycoprotein IIb-IIIa Antagonist Inhibition of Platelet Activation, Aggregation, and Procoagulant Activity.
Journal of the American Heart Association 2013;2(3):e000026.
2012: H Chang; E J Dix; Marc R Barnard; Y F Li; Alan D Michelson; G E Wright; I B Yanachkov; Andrew L Frelinger
Modified diadenosine tetraphosphates with dual specificity for P2Y1 and P2Y12 are potent antagonists of ADP-induced platelet activation.
Journal of thrombosis and haemostasis : JTH 2012;10(12):2573-80.
2012: Andrew L Frelinger; Ronald D Lee; Deepak L Bhatt; Julie K Brooks; Darcy J Mulford; Anu Nigam; Sai Nudurupati; Jingtao Wu; Alan D Michelson
A randomized, 2-period, crossover design study to assess the effects of dexlansoprazole, lansoprazole, esomeprazole, and omeprazole on the steady-state pharmacokinetics and pharmacodynamics of clopidogrel in healthy volunteers.
Journal of the American College of Cardiology 2012;59(14):1304-11.
2011: Jessica L Mega; Alan D Michelson; Michael J Pencina; William J Rogers; Christian T Ruff; Benjamin M Scirica; Dominick J Angiolillo; Charles Contant; Andrew L Frelinger; Willibald Hochholzer; Steven Isserman; Dean J Kereiakes; Michael J Kluk; Janina A Longtine; Marc S Sabatine
Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease.
JAMA : the journal of the American Medical Association 2011;306(20):2221-8.
2011: Frank A J L Scheer; Marc R Barnard; Lauren A Doamekpor; Heather Evoniuk; Andrew L Frelinger; Erin E Kelly; Mary McCarthy; Alan D Michelson; Steven A Shea
The human endogenous circadian system causes greatest platelet activation during the biological morning independent of behaviors.
PloS one 2011;6(9):e24549.
2010: Andrew L Frelinger; Marc R Barnard; Marsha L Fox; Alan D Michelson
The Platelet Activity After Clopidogrel Termination (PACT) study.
Circulation. Cardiovascular interventions 2010;3(5):442-9.
2010: Hung Chang; Ivan B Yanachkov; Alan D Michelson; YouFu Li; Marc R Barnard; George E Wright; Andrew L Frelinger
Agonist and antagonist effects of diadenosine tetraphosphate, a platelet dense granule constituent, on platelet P2Y1, P2Y12 and P2X1 receptors.
Thrombosis research 2010;125(2):159-65.
2010: Karin Przyklenk; Andrew L Frelinger; Matthew D Linden; Peter Whittaker; Youfu Li; Marc R Barnard; J Adams; M Morgan; H Al-Shamma; Alan D Michelson
Targeted inhibition of the serotonin 5HT2A receptor improves coronary patency in an in vivo model of recurrent thrombosis.
Journal of thrombosis and haemostasis : JTH 2010;8(2):331-40.
2009: Michelle L O'Donoghue; Eugene Braunwald; Elliott M Antman; Sabina A Murphy; Eric R Bates; Yoseph Rozenman; Alan D Michelson; Raymond W Hautvast; Peter N Ver Lee; Sandra L Close; Lei Shen; Jessica L Mega; Marc S Sabatine; Stephen D Wiviott
Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials.
Lancet 2009;374(9694):989-97.
2009: Chad E Darling; Alan D Michelson; Gregory A Volturo; Karin Przyklenk
Platelet reactivity and the identification of acute coronary syndromes in the emergency department.
Journal of thrombosis and thrombolysis 2009;28(1):31-7.
2009: FJ Bednarek; Stephen Bean; Marc R Barnard; Andrew L Frelinger; Alan D Michelson
The platelet hyporeactivity of extremely low birth weight neonates is age-dependent.
Thrombosis research 2009;124(1):42-5.
2009: Alan D Michelson
Methods for the measurement of platelet function.
The American journal of cardiology 2009;103(3 Suppl):20A-26A.
2008: Alan D Michelson
P2Y12 antagonism: promises and challenges.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(3):s33-8.
2008: Andrew L Frelinger; Joseph A Jakubowski; Youfu Li; Marc R Barnard; Matthew D Linden; I Tarnow; Marsha L Fox; Atsuhiro Sugidachi; Kenneth J Winters; Mark I Furman; Alan D Michelson
The active metabolite of prasugrel inhibits adenosine diphosphate- and collagen-stimulated platelet procoagulant activities.
Journal of thrombosis and haemostasis : JTH 2008;6(2):359-65.
2008: Matthew D Linden; Marc R Barnard; Andrew L Frelinger; Alan D Michelson; Karin Przyklenk
Effect of adenosine A2 receptor stimulation on platelet activation-aggregation: differences between canine and human models.
Thrombosis research 2008;121(5):689-98.
2007: Stephen D Wiviott; Dietmar Trenk; Andrew L Frelinger; Michelle O'Donoghue; Franz-Josef Neumann; Alan D Michelson; Dominick J Angiolillo; Hanoch Hod; Gilles Montalescot; Debra L Miller; Joseph A Jakubowski; Richard Cairns; Sabina A Murphy; Carolyn H McCabe; Elliott M Antman; Eugene Braunwald
Prasugrel compared with high loading- and maintenance-dose clopidogrel in patients with planned percutaneous coronary intervention: the Prasugrel in Comparison to Clopidogrel for Inhibition of Platelet Activation and Aggregation-Thrombolysis in Myocardial Infarction 44 trial.
Circulation 2007;116(25):2923-32.
2007: Andrew L Frelinger; Joseph A Jakubowski; Youfu Li; Marc R Barnard; Marsha L Fox; Matthew D Linden; Atsuhiro Sugidachi; Kenneth J Winters; Mark I Furman; Alan D Michelson
The active metabolite of prasugrel inhibits ADP-stimulated thrombo-inflammatory markers of platelet activation: Influence of other blood cells, calcium, and aspirin.
Thrombosis and haemostasis 2007;98(1):192-200.
2007: Matthew D Linden; Mark I Furman; Andrew L Frelinger; Marsha L Fox; Marc R Barnard; Youfu Li; Karin Przyklenk; Alan D Michelson
Indices of platelet activation and the stability of coronary artery disease.
Journal of thrombosis and haemostasis : JTH 2007;5(4):761-5.
2007: Inge Tarnow; Alan D Michelson; Andrew L Frelinger; Matthew D Linden; Youfu Li; Marsha L Fox; Marc R Barnard; Brian P O'Sullivan
Cystic fibrosis heterozygotes do not have increased platelet activation.
Thrombosis research 2007;121(2):159-62.
2007: Paul Harrison; Andrew L Frelinger; Mark I Furman; Alan D Michelson
Measuring antiplatelet drug effects in the laboratory.
Thrombosis research 2007;120(3):323-36.
2007: Alan D Michelson; Matthew D Linden; Mark I Furman; Youfu Li; Marc R Barnard; Marsha L Fox; Wei C Lau; Thomas J McLaughlin; Andrew L Frelinger
Evidence that pre-existent variability in platelet response to ADP accounts for 'clopidogrel resistance'.
Journal of thrombosis and haemostasis : JTH 2007;5(1):75-81.
2006: Matthew D Linden; Peter Whittaker; Andrew L Frelinger; Marc R Barnard; Alan D Michelson; Karin Przyklenk
Preconditioning ischemia attenuates molecular indices of platelet activation-aggregation.
Journal of thrombosis and haemostasis : JTH 2006;4(12):2670-7.
2006: Alan D Michelson; Andrew L Frelinger; Mark I Furman
Current options in platelet function testing.
The American journal of cardiology 2006;98(10A):4N-10N.
2006: Andrew L Frelinger; Mark I Furman; Matthew D Linden; Youfu Li; Marsha L Fox; Marc R Barnard; Alan D Michelson
Residual arachidonic acid-induced platelet activation via an adenosine diphosphate-dependent but cyclooxygenase-1- and cyclooxygenase-2-independent pathway: a 700-patient study of aspirin resistance.
Circulation 2006;113(25):2888-96.
2006: Brian P O'Sullivan; Alan D Michelson
The inflammatory role of platelets in cystic fibrosis.
American journal of respiratory and critical care medicine 2006;173(5):483-90.
2006: Stephen D Wiviott; Alan D Michelson; Peter B Berger; Norman E Lepor; Dean J Kereiakes
Therapeutic goals for effective platelet inhibition: a consensus document.
Reviews in cardiovascular medicine 2006;7(4):214-25.
2006: Alan D Michelson
Evaluation of platelet function by flow cytometry.
Pathophysiology of haemostasis and thrombosis 2006;35(1-2):67-82.
2006: Alan D Michelson
Aspirin resistance.
Pathophysiology of haemostasis and thrombosis 2006;35(1-2):5-9.
2005: Marc R Barnard; Matthew D Linden; Andrew L Frelinger; Youfu Li; Marsha L Fox; Mark I Furman; Alan D Michelson
Effects of platelet binding on whole blood flow cytometry assays of monocyte and neutrophil procoagulant activity.
Journal of thrombosis and haemostasis : JTH 2005;3(11):2563-70.
2005: Andrew L Frelinger; Alan D Michelson
Clopidogrel linking evaluation of platelet response variability to mechanism of action.
Journal of the American College of Cardiology 2005;46(4):646-7.
2005: Brian P O'Sullivan; Matthew D Linden; Andrew L Frelinger; Marc R Barnard; Michele Spencer-Manzon; James E Morris; Raneem O Salem; Michael Laposata; Alan D Michelson
Platelet activation in cystic fibrosis.
Blood 2005;105(12):4635-41.
2005: Alan D Michelson; M Cattaneo; J W Eikelboom; Paul A Gurbel; K Kottke-Marchant; T J Kunicki; F M Pulcinelli; C Cerletti; A K Rao
Aspirin resistance: position paper of the Working Group on Aspirin Resistance.
Journal of thrombosis and haemostasis : JTH 2005;3(6):1309-11.
2005: C Robert Valeri; Hollace MacGregor; Marc R Barnard; L Summaria; Alan D Michelson; Gina Ragno
Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets.
Vox sanguinis 2005;88(2):122-9.
2005: Mark I Furman; Lori A Krueger; Matthew D Linden; Marsha L Fox; Steven P Ball; Marc R Barnard; Andrew L Frelinger; Alan D Michelson
GPIIb-IIIa antagonists reduce thromboinflammatory processes in patients with acute coronary syndromes undergoing percutaneous coronary intervention.
Journal of thrombosis and haemostasis : JTH 2005;3(2):312-20.
2005: Alan D Michelson
Platelet function testing in cardiovascular diseases.
Hematology (Amsterdam, Netherlands) 2005;10 Suppl 1():132-7.
2004: Alan D Michelson
Platelet function testing in cardiovascular diseases.
Circulation 2004;110(19):e489-93.
2004: Matthew D Linden; Andrew L Frelinger; Marc R Barnard; Karin Przyklenk; Mark I Furman; Alan D Michelson
Application of flow cytometry to platelet disorders.
Seminars in thrombosis and hemostasis 2004;30(5):501-11.
2004: C Robert Valeri; Hollace MacGregor; Marc R Barnard; L Summaria; Alan D Michelson; Gina Ragno
In vitro testing of fresh and lyophilized reconstituted human and baboon platelets.
Transfusion 2004;44(10):1505-12.
2004: Mark I Furman; Andrew L Frelinger; Alan D Michelson
GPIIb/IIIa inhibitor-induced dethrombosis.
Journal of thrombosis and thrombolysis 2004;18(1):11-7.
2004: Mark I Furman; Lori A Krueger; Matthew D Linden; Marc R Barnard; Andrew L Frelinger; Alan D Michelson
Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.
Journal of the American College of Cardiology 2004;43(12):2319-25.
2003: Andrew L Frelinger; Mark I Furman; Marc R Barnard; Lori A Krueger; Michael W Dae; Alan D Michelson
Combined effects of mild hypothermia and glycoprotein IIb/IIIa antagonists on platelet-platelet and leukocyte-platelet aggregation.
The American journal of cardiology 2003;92(9):1099-101.
2003: Kishore R Alugupalli; Alan D Michelson; Isabelle Joris; Tom G Schwan; Kairbaan M Hodivala-Dilke; Richard O Hynes; John M Leong
Spirochete-platelet attachment and thrombocytopenia in murine relapsing fever borreliosis.
Blood 2003;102(8):2843-50.
2003: Alan D Michelson
Platelet inhibitor therapy: mechanisms of action and clinical use.
Journal of thrombosis and thrombolysis 2003;16(1-2):13-5.
2003: Alan D Michelson
How platelets work: platelet function and dysfunction.
Journal of thrombosis and thrombolysis 2003;16(1-2):7-12.
2003: Marc R Barnard; Lori A Krueger; Andrew L Frelinger; Mark I Furman; Alan D Michelson
Whole blood analysis of leukocyte-platelet aggregates.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2003;Chapter 6():Unit 6.15.
2003: Changyi (Johnny) Chen; Jing-fei Dong; Carol Sun; Angela L Bergeron; Latresha McBride; M Pillai; M R Barnard; J Salmon; Alan D Michelson; Paul F Bray
Platelet FcgammaRIIA His131Arg polymorphism and platelet function: antibodies to platelet-bound fibrinogen induce platelet activation.
Journal of thrombosis and haemostasis : JTH 2003;1(2):355-62.
2003: Mark I Furman; Dean J Kereiakes; Lori A Krueger; Michele N Mueller; Thomas M Broderick; John F Schneider; Wendy L Howard; Marsha L Fox; Marc R Barnard; Andrew L Frelinger; Alan D Michelson
Quantification of abciximab-induced platelet inhibition is assay dependent: a comparative study in patients undergoing percutaneous coronary intervention.
American heart journal 2003;145(2):e6.
2003: R Brannon Claytor; Alan D Michelson; Jian-Ming Li; Andrew L Frelinger; Michael J Rohrer; Charles S C Garnette; Marc R Barnard; Lori A Krueger; Mark I Furman
The cleaved peptide of PAR1 is a more potent stimulant of platelet-endothelial cell adhesion than is thrombin.
Journal of vascular surgery 2003;37(2):440-5.
2002: Michael J Rohrer; R Brannon Claytor; Charles S C Garnette; Craig C Powell; Marc R Barnard; Mark I Furman; Alan D Michelson
Platelet-monocyte aggregates in patients with chronic venous insufficiency remain elevated following correction of reflux.
Cardiovascular surgery (London, England) 2002;10(5):464-9.
2002: Stanley J Marciniak; Mary Ann Mascelli; Mark I Furman; Alan D Michelson; Joseph A Jakubowski; Robert E Jordan; Peter J Marchese; Andrew L Frelinger
An additional mechanism of action of abciximab: dispersal of newly formed platelet aggregates.
Thrombosis and haemostasis 2002;87(6):1020-5.
2002: Guy L Wheeler; Gregory A Braden; Steven R Steinhubl; Dean J Kereiakes; Kandice Kottke-Marchant; Alan D Michelson; Mark I Furman; Michele N Mueller; David J Moliterno; David C Sane
The Ultegra rapid platelet-function assay: comparison to standard platelet function assays in patients undergoing percutaneous coronary intervention with abciximab therapy.
American heart journal 2002;143(4):602-11.
2002: Lori A Krueger; Marc R Barnard; Andrew L Frelinger; Mark I Furman; Alan D Michelson
Immunophenotypic analysis of platelets.
Current protocols in cytometry / editorial board, J. Paul Robinson, managing editor ... [et al.] 2002;Chapter 6():Unit 6.10.
2001: Mark I Furman; Dean J Kereiakes; Lori A Krueger; Michele N Mueller; K Pieper; Thomas M Broderick; John F Schneider; Wendy L Howard; Marsha L Fox; Marc R Barnard; Andrew L Frelinger; Alan D Michelson
Leukocyte-platelet aggregation, platelet surface P-selectin, and platelet surface glycoprotein IIIa after percutaneous coronary intervention: Effects of dalteparin or unfractionated heparin in combination with abciximab.
American heart journal 2001;142(5):790-8.
2001: Mark I Furman; Marc R Barnard; Lori A Krueger; Marsha L Fox; E A Shilale; Darleen Lessard; P Marchese; Andrew L Frelinger; R J Goldberg; Alan D Michelson
Circulating monocyte-platelet aggregates are an early marker of acute myocardial infarction.
Journal of the American College of Cardiology 2001;38(4):1002-6.
2001: Alan D Michelson; Marc R Barnard; Lori A Krueger; C R Valeri; Mark I Furman
Circulating monocyte-platelet aggregates are a more sensitive marker of in vivo platelet activation than platelet surface P-selectin: studies in baboons, human coronary intervention, and human acute myocardial infarction.
Circulation 2001;104(13):1533-7.
2001: Andrew L Frelinger; Mark I Furman; Lori A Krueger; Marc R Barnard; Alan D Michelson
Dissociation of glycoprotein IIb/IIIa antagonists from platelets does not result in fibrinogen binding or platelet aggregation.
Circulation 2001;104(12):1374-9.
2001: Kishore R Alugupalli; Alan D Michelson; Marc R Barnard; John M Leong
Serial determinations of platelet counts in mice by flow cytometry.
Thrombosis and haemostasis 2001;86(2):668-71.
2001: R Brannon Claytor; Jian-Ming Li; Mark I Furman; Charles S C Garnette; Michael J Rohrer; Marc R Barnard; Lori A Krueger; Andrew L Frelinger; Alan D Michelson
Laser scanning cytometry: a novel method for the detection of platelet--endothelial cell adhesion.
Cytometry 2001;43(4):308-13.
2001: Kishore R Alugupalli; Alan D Michelson; Marc R Barnard; Douglas Robbins; Jenifer Coburn; E K Baker; M H Ginsberg; Tom G Schwan; John M Leong
Platelet activation by a relapsing fever spirochaete results in enhanced bacterium-platelet interaction via integrin alphaIIbbeta3 activation.
Molecular microbiology 2001;39(2):330-40.
2000: Mark I Furman; P Nurden; M C Berndt; A T Nurden; SE Benoit; Marc R Barnard; Frederick A Ofosu; Alan D Michelson
The cleaved peptide of PAR1 results in a redistribution of the platelet surface GPIb-IX-V complex to the surface-connected canalicular system.
Thrombosis and haemostasis 2000;84(5):897-903.
2000: Alan D Michelson; D Rajasekhar; FJ Bednarek; Marc R Barnard
Platelet and platelet-derived microparticle surface factor V/Va binding in whole blood: differences between neonates and adults.
Thrombosis and haemostasis 2000;84(4):689-94.
2000: Mark I Furman; Lori A Krueger; Andrew L Frelinger; Marc R Barnard; Mary Ann Mascelli; Marian T Nakada; Alan D Michelson
GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood.
Thrombosis and haemostasis 2000;84(3):492-8.
2000: Mark I Furman; A L Frelinger III; Alan D Michelson
Antithrombotic therapy in the cardiac catheterization laboratory: focus on antiplatelet agents.
Current cardiology reports 2000;2(5):386-94.
2000: Alan D Michelson; Marc R Barnard; Lori A Krueger; Andrew L Frelinger; Mark I Furman
Evaluation of platelet function by flow cytometry.
Methods (San Diego, Calif.) 2000;21(3):259-70.
2000: Alan D Michelson; M I Furman; Pascal J Goldschmidt-Clermont; Mary Ann Mascelli; Craig W Hendrix; L Coleman; J Hamlington; M R Barnard; Thomas S Kickler; D J Christie; S Kundu; Paul F Bray
Platelet GP IIIa Pl(A) polymorphisms display different sensitivities to agonists.
Circulation 2000;101(9):1013-8.
2000: Alan D Michelson
Flow cytometric analysis of platelets.
Vox sanguinis 2000;78 Suppl 2():137-42.
2000: Joseph Loscalzo; J Freedman; A Inbal; J F Keaney; Alan D Michelson; J A Vita
Nitric oxide insufficiency and arterial thrombosis.
Transactions of the American Clinical and Climatological Association 2000;111():158-63.
1999: Craig C Powell; Michael J Rohrer; Marc R Barnard; BD Peyton; Mark I Furman; Alan D Michelson
Chronic venous insufficiency is associated with increased platelet and monocyte activation and aggregation.
Journal of vascular surgery 1999;30(5):844-51.
1999: Alan D Michelson; M I Furman
Laboratory markers of platelet activation and their clinical significance.
Current opinion in hematology 1999;6(5):342-8.
1999: Marc R Barnard; Hollace MacGregor; Gina Ragno; Linda E Pivacek; Shukri F Khuri; Alan D Michelson; C Robert Valeri
Fresh, liquid-preserved, and cryopreserved platelets: adhesive surface receptors and membrane procoagulant activity.
Transfusion 1999;39(8):880-8.
1999: Marc R Barnard; Hollace MacGregor; R Mercier; Gina Ragno; Linda E Pivacek; Herbert B Hechtman; Alan D Michelson; C Robert Valeri
Platelet surface p-selectin, platelet-granulocyte heterotypic aggregates, and plasma-soluble p-selectin during plateletpheresis.
Transfusion 1999;39(7):735-41.
1999: Alan D Michelson; Marc R Barnard; Shukri F Khuri; M J Rohrer; Hollace MacGregor; C Robert Valeri
The effects of aspirin and hypothermia on platelet function in vivo.
British journal of haematology 1999;104(1):64-8.
1999: Shukri F Khuri; Nancy A Healey; Hollace MacGregor; Marc R Barnard; I O Szymanski; Vladimir Birjiniuk; Alan D Michelson; D R Gagnon; C Robert Valeri
Comparison of the effects of transfusions of cryopreserved and liquid-preserved platelets on hemostasis and blood loss after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 1999;117(1):172-83; discussion 183-4.
1998: Jonathan Himmelfarb; S Nelson; Ellen McMonagle; D Holbrook; SE Benoit; Alan D Michelson; K Ault
Elevated plasma glycocalicin levels and decreased ristocetin-induced platelet agglutination in hemodialysis patients.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1998;32(1):132-8.
1998: BD Peyton; Michael J Rohrer; Mark I Furman; Marc R Barnard; L J Rodino; SE Benoit; Herbert B Hechtman; C R Valeri; Alan D Michelson
Patients with venous stasis ulceration have increased monocyte-platelet aggregation.
Journal of vascular surgery 1998;27(6):1109-15; discussion 1115-6.
1998: Mark I Furman; L Liu; SE Benoit; RC Becker; Marc R Barnard; Alan D Michelson
The cleaved peptide of the thrombin receptor is a strong platelet agonist.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(6):3082-7.
1998: Mark I Furman; SE Benoit; Marc R Barnard; C R Valeri; M L Borbone; RC Becker; Herbert B Hechtman; Alan D Michelson
Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease.
Journal of the American College of Cardiology 1998;31(2):352-8.
1998: Alan D Michelson
Platelet function in the newborn.
Seminars in thrombosis and hemostasis 1998;24(6):507-12.
1997: Jane E Freedman; Joseph Loscalzo; Marc R Barnard; C Alpert; John F Keaney; Alan D Michelson
Nitric oxide released from activated platelets inhibits platelet recruitment.
The Journal of clinical investigation 1997;100(2):350-6.
1997: D Rajasekhar; Marc R Barnard; FJ Bednarek; Alan D Michelson
Platelet hyporeactivity in very low birth weight neonates.
Thrombosis and haemostasis 1997;77(5):1002-7.
1996: Alan D Michelson; Marc R Barnard; H B Hechtman; Hollace MacGregor; R J Connolly; Joseph Loscalzo; C Robert Valeri
In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(21):11877-82.
1996: Eric F Grabowski; I K Jang; H Gold; C Head; SE Benoit; Alan D Michelson
Variability of platelet degranulation by different contrast media.
Academic radiology 1996;3 Suppl 3():S485-7.
1996: Eric F Grabowski; S E Boor; L J Rodino; I K Jang; H Gold; Alan D Michelson
Platelets are degranulated by some, but not all, contrast media.
Academic radiology 1996;3 Suppl 2():S328-30.
1996: Gilbert R Upchurch Jr; C Robert Valeri; Shukri F Khuri; Michael J Rohrer; GN Welch; Hollace MacGregor; Gina Ragno; S Francis; L J Rodino; Alan D Michelson; Joseph Loscalzo
Effect of heparin on fibrinolytic activity and platelet function in vivo.
The American journal of physiology 1996;271(2 Pt 2):H528-34.
1996: Alan D Michelson
Flow cytometry: a clinical test of platelet function.
Blood 1996;87(12):4925-36.
1996: Alan D Michelson; SE Benoit; Mark I Furman; W L Breckwoldt; Michael J Rohrer; Marc R Barnard; Joseph Loscalzo
Effects of nitric oxide/EDRF on platelet surface glycoproteins.
The American journal of physiology 1996;270(5 Pt 2):H1640-8.
1996: J M Li; R S Podolsky; Michael J Rohrer; Bruce S Cutler; M T Massie; Marc R Barnard; Alan D Michelson
Adhesion of activated platelets to venous endothelial cells is mediated via GPIIb/IIIa.
The Journal of surgical research 1996;61(2):543-8.
1996: Jane E Freedman; Joseph Loscalzo; SE Benoit; C Robert Valeri; Marc R Barnard; Alan D Michelson
Decreased platelet inhibition by nitric oxide in two brothers with a history of arterial thrombosis.
The Journal of clinical investigation 1996;97(4):979-87.
1996: Alan D Michelson; SE Benoit; Mark I Furman; Marc R Barnard; P Nurden; A T Nurden
The platelet surface expression of glycoprotein V is regulated by two independent mechanisms: proteolysis and a reversible cytoskeletal-mediated redistribution to the surface-connected canalicular system.
Blood 1996;87(4):1396-408.
1995: Marc R Barnard; Alan D Michelson
Images in clinical medicine. A morphologic question.
The New England journal of medicine 1995;333(16):1051.
1995: S G Kamat; Alan D Michelson; SE Benoit; Joel L Moake; D Rajasekhar; J David Hellums; Michael H Kroll; Andrew I Schafer
Fibrinolysis inhibits shear stress-induced platelet aggregation.
Circulation 1995;92(6):1399-407.
1995: Eric F Grabowski; I K Jang; H Gold; I F Palacios; S E Boor; L J Rodino; Alan D Michelson
Platelet degranulation induced by some contrast media is independent of their nonionic vs ionic nature.
Acta radiologica. Supplementum 1995;399():182-4.
1994: D Rajasekhar; A S Kestin; F J Bednarek; P A Ellis; Marc R Barnard; Alan D Michelson
Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood.
Thrombosis and haemostasis 1994;72(6):957-63.
1994: C A LaRosa; Michael J Rohrer; SE Benoit; Marc R Barnard; Alan D Michelson
Neutrophil cathepsin G modulates the platelet surface expression of the glycoprotein (GP) Ib-IX complex by proteolysis of the von Willebrand factor binding site on GPIb alpha and by a cytoskeletal-mediated redistribution of the remainder of the complex.
Blood 1994;84(1):158-68.
1994: Alan D Michelson; JD Wencel-Drake; A S Kestin; Marc R Barnard
Platelet activation results in a redistribution of glycoprotein IV (CD36).
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(7):1193-201.
1994: Alan D Michelson; SE Benoit; Michael H Kroll; J M Li; Michael J Rohrer; A S Kestin; Marc R Barnard
The activation-induced decrease in the platelet surface expression of the glycoprotein Ib-IX complex is reversible.
Blood 1994;83(12):3562-73.
1994: Eric F Grabowski; C Head; H A Michail; I K Jang; H Gold; SE Benoit; Alan D Michelson
Effects of contrast media on platelet activation using flowing whole blood aggregometry and flow cytometry of platelet membrane glycoproteins.
Investigative radiology 1994;29 Suppl 2():S198-200.
1994: Alan D Michelson; Hollace MacGregor; Marc R Barnard; A S Kestin; Michael J Rohrer; C Robert Valeri
Reversible inhibition of human platelet activation by hypothermia in vivo and in vitro.
Thrombosis and haemostasis 1994;71(5):633-40.
1994: Alan D Michelson
Platelet activation by thrombin can be directly measured in whole blood through the use of the peptide GPRP and flow cytometry: methods and clinical applications.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 1994;5(1):121-31.
1994: C A LaRosa; Michael J Rohrer; SE Benoit; L J Rodino; Marc R Barnard; Alan D Michelson
Human neutrophil cathepsin G is a potent platelet activator.
Journal of vascular surgery 1994;19(2):306-18; discussion 318-9.
1993: Eric F Grabowski; C Head; Alan D Michelson
Nonionic contrast media. Procoagulants or clotting innocents?
Investigative radiology 1993;28 Suppl 5():S21-4.
1993: MA Orchard; C S Goodchild; C R Prentice; J A Davies; SE Benoit; L J Creighton-Kemsford; P J Gaffney; Alan D Michelson
Aprotinin reduces cardiopulmonary bypass-induced blood loss and inhibits fibrinolysis without influencing platelets.
British journal of haematology 1993;85(3):533-41.
1993: A S Kestin; P A Ellis; Marc R Barnard; A Errichetti; B A Rosner; Alan D Michelson
Effect of strenuous exercise on platelet activation state and reactivity.
Circulation 1993;88(4 Pt 1):1502-11.
1992: Michael J Rohrer; A S Kestin; P A Ellis; Marc R Barnard; L Rodino; W L Breckwoldt; J M Li; Alan D Michelson
High-dose heparin suppresses platelet alpha granule secretion.
Journal of vascular surgery 1992;15(6):1000-8; discussion 1008-9.
1992: Alan D Michelson
Thrombin-induced down-regulation of the platelet membrane glycoprotein Ib-IX complex.
Seminars in thrombosis and hemostasis 1992;18(1):18-27.
1991: G B Matic; S R Jaspers; T B Miller; Alan D Michelson
Platelet glycogen synthase: further characterization and effect of insulin.
Thrombosis research 1991;63(4):427-32.
1991: N Yamamoto; N J Greco; Marc R Barnard; K Tanoue; H Yamazaki; G A Jamieson; Alan D Michelson
Glycoprotein Ib (GPIb)-dependent and GPIb-independent pathways of thrombin-induced platelet activation.
Blood 1991;77(8):1740-8.
1991: Alan D Michelson; P A Ellis; Marc R Barnard; G B Matic; A F Viles; A S Kestin
Downregulation of the platelet surface glycoprotein Ib-IX complex in whole blood stimulated by thrombin, adenosine diphosphate, or an in vivo wound.
Blood 1991;77(4):770-9.
1990: Alan D Michelson; J M Gore; M E Rybak; Carol A Sherman; Marc R Barnard
Effect of in vivo infusion of recombinant tissue-type plasminogen activator on platelet glycoprotein Ib.
Thrombosis research 1990;60(5):421-4.
1990: Alan D Michelson; Marc R Barnard
Plasmin-induced redistribution of platelet glycoprotein Ib.
Blood 1990;76(10):2005-10.
1988: Alan D Michelson; B Adelman; Marc R Barnard; E Carroll; R I Handin
Platelet storage results in a redistribution of glycoprotein Ib molecules. Evidence for a large intraplatelet pool of glycoprotein Ib.
The Journal of clinical investigation 1988;81(6):1734-40.
1988: Alan D Michelson; Marc R Barnard
Thrombin-induced changes in platelet membrane glycoproteins.
Progress in clinical and biological research 1988;283():159-62.
1988: Alan D Michelson
Flow cytometric detection of distinct subpopulations of platelets in individual patients.
Progress in clinical and biological research 1988;283():131-6.
1987: Alan D Michelson; Marc R Barnard
Thrombin-induced changes in platelet membrane glycoproteins Ib, IX, and IIb-IIIa complex.
Blood 1987;70(5):1673-8.
1986: B Adelman; Alan D Michelson; J Greenberg; R I Handin
Proteolysis of platelet glycoprotein Ib by plasmin is facilitated by plasmin lysine-binding regions.
Blood 1986;68(6):1280-4.
1985: B Adelman; Alan D Michelson; R I Handin; K A Ault
Evaluation of platelet glycoprotein Ib by fluorescence flow cytometry.
Blood 1985;66(2):423-7.
1985: B Adelman; Alan D Michelson; Joseph Loscalzo; J Greenberg; R I Handin
Plasmin effect on platelet glycoprotein Ib-von Willebrand factor interactions.
Blood 1985;65(1):32-40.