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Caroline Beard

Research Profile

Living Beings

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Publications

TOP 3
Bryce W Carey; Styliani Markoulaki; Caroline Beard; Jacob Hanna; Rudolf Jaenisch
Single-gene transgenic mouse strains for reprogramming adult somatic cells.
Dirk Hockemeyer; Frank Soldner; Caroline Beard; Qing Gao; Maisam Mitalipova; Russell C DeKelver; George E Katibah; Ranier Amora; Elizabeth A Boydston; Bryan Zeitler; Xiangdong Meng; Jeffrey C Miller; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; Rudolf Jaenisch
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Daniela Tropea; Emanuela Giacometti; Nathan R Wilson; Caroline Beard; Cortina McCurry; Dong Dong Fu; Ruth Flannery; Rudolf Jaenisch; Mriganka Sur
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice.

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All Publications

2010: Bryce W Carey; Styliani Markoulaki; Caroline Beard; Jacob Hanna; Rudolf Jaenisch
Single-gene transgenic mouse strains for reprogramming adult somatic cells.
Nature methods 2010;7(1):56-9.
2009: Dirk Hockemeyer; Frank Soldner; Caroline Beard; Qing Gao; Maisam Mitalipova; Russell C DeKelver; George E Katibah; Ranier Amora; Elizabeth A Boydston; Bryan Zeitler; Xiangdong Meng; Jeffrey C Miller; Lei Zhang; Edward J Rebar; Philip D Gregory; Fyodor D Urnov; Rudolf Jaenisch
Efficient targeting of expressed and silent genes in human ESCs and iPSCs using zinc-finger nucleases.
Nature biotechnology 2009;27(9):851-7.
2009: Daniela Tropea; Emanuela Giacometti; Nathan R Wilson; Caroline Beard; Cortina McCurry; Dong Dong Fu; Ruth Flannery; Rudolf Jaenisch; Mriganka Sur
Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(6):2029-34.
2009: Styliani Markoulaki; Jacob Hanna; Caroline Beard; Bryce W Carey; Albert Cheng; Christopher J Lengner; Jessica A Dausman; Dongdong Fu; Qing Gao; Su Wu; John P Cassady; Rudolf Jaenisch
Transgenic mice with defined combinations of drug-inducible reprogramming factors.
Nature biotechnology 2009;27(2):169-71.
2007: Jacob Hanna; Marius Wernig; Styliani Markoulaki; Chiao-Wang Sun; Alexander Meissner; John P Cassady; Caroline Beard; Tobias Brambrink; Li-Chen Wu; Tim M Townes; Rudolf Jaenisch
Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin.
Science (New York, N.Y.) 2007;318(5858):1920-3.
2007: Jing Zhang; Yangang Liu; Caroline Beard; David A Tuveson; Rudolf Jaenisch; Tyler Jacks; Harvey Lodish
Expression of oncogenic K-ras from its endogenous promoter leads to a partial block of erythroid differentiation and hyperactivation of cytokine-dependent signaling pathways.
Blood 2007;109(12):5238-41.
2007: Emanuela Giacometti; Sandra Luikenhuis; Caroline Beard; Rudolf Jaenisch
Partial rescue of MeCP2 deficiency by postnatal activation of MeCP2.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(6):1931-6.
2006: Caroline Beard; Konrad Hochedlinger; Kathrin Plath; Anton Wutz; Rudolf Jaenisch
Efficient method to generate single-copy transgenic mice by site-specific integration in embryonic stem cells.
Genesis (New York, N.Y. : 2000) 2006;44(1):23-8.
2005: Konrad Hochedlinger; Yasuhiro Yamada; Caroline Beard; Rudolf Jaenisch
Ectopic expression of Oct-4 blocks progenitor-cell differentiation and causes dysplasia in epithelial tissues.
Cell 2005;121(3):465-77.
2001: G Fan; Caroline Beard; Richard Z Chen; G Csankovszki; Yi E Sun; MS Siniaia; Detlev Biniszkiewicz; Brian Bates; P P Lee; R Kuhn; Andreas Trumpp; C Poon; C B Wilson; Rudolf Jaenisch
DNA hypomethylation perturbs the function and survival of CNS neurons in postnatal animals.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(3):788-97.
2001: Laurie Jackson-Grusby; Caroline Beard; Richard Possemato; Matthew Tudor; D Fambrough; G Csankovszki; Jessica Dausman; P Lee; C Wilson; Eric S Lander; Rudolf Jaenisch
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation.
Nature genetics 2001;27(1):31-9.
2000: David Lombard; Caroline Beard; Brad Johnson; Robert Marciniak; Jessica Dausman; R Bronson; J E Buhlmann; R Lipman; R Curry; A Sharpe; Rudolf Jaenisch; Leonard Guarente
Mutations in the WRN gene in mice accelerate mortality in a p53-null background.
Molecular and cellular biology 2000;20(9):3286-91.
1998: Richard Z Chen; U Pettersson; Caroline Beard; Laurie Jackson-Grusby; Rudolf Jaenisch
DNA hypomethylation leads to elevated mutation rates.
Nature 1998;395(6697):89-93.
1998: Rudolf Jaenisch; Caroline Beard; Janice Y. Lee; York Marahrens; Barbara Panning
Mammalian X chromosome inactivation.
Novartis Foundation symposium 1998;214():200-9; discussion 209-13, 228-32.
1996: K L Tucker; Caroline Beard; J Dausmann; Laurie Jackson-Grusby; P W Laird; H Lei; E Li; Rudolf Jaenisch
Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes.
Genes & development 1996;10(8):1008-20.
1995: Caroline Beard; E Li; Rudolf Jaenisch
Loss of methylation activates Xist in somatic but not in embryonic cells.
Genes & development 1995;9(19):2325-34.
1993: E Li; Caroline Beard; Rudolf Jaenisch
Role for DNA methylation in genomic imprinting.
Nature 1993;366(6453):362-5.
1993: W M Strauss; Jessica Dausman; Caroline Beard; C Johnson; J B Lawrence; Rudolf Jaenisch
Germ line transmission of a yeast artificial chromosome spanning the murine alpha 1(I) collagen locus.
Science (New York, N.Y.) 1993;259(5103):1904-7.