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Lawrence Middaugh

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William C Griffin; Robin W McGovern; Lawrence D Middaugh; Guinevere H Bell; Patrick K Randall; Kennerly S Patrick
Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice.
Ann-Charlotte E. Granholm-Bentley; Vandana Zaman; Jennifer Godbee; Michael Smith; Riad Ramadan; Claudia Umphlet; Patrick Randall; Narayan R Bhat; Baerbel Rohrer; Lawrence D Middaugh; Heather A Boger
Prenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous mice.
Heather A Boger; P Mannangatti; Devadoss J Samuvel; A J Saylor; T S Bender; Jacqueline McGinty; A M Fortress; Vandana Zaman; Peng Huang; Lawrence D Middaugh; Patrick K Randall; Lankupalle D Jayanthi; Baerbel Rohrer; K L Helke; Ann-Charlotte E. Granholm-Bentley; Sammanda Ramamoorthy
Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging.

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2013: William C Griffin; Robin W McGovern; Lawrence D Middaugh; Guinevere H Bell; Patrick K Randall; Kennerly S Patrick
Interactive effects of methylphenidate and alcohol on discrimination, conditioned place preference and motor coordination in C57BL/6J mice.
Psychopharmacology 2013;225(3):613-25.
2011: Ann-Charlotte E. Granholm-Bentley; Vandana Zaman; Jennifer Godbee; Michael Smith; Riad Ramadan; Claudia Umphlet; Patrick Randall; Narayan R Bhat; Baerbel Rohrer; Lawrence D Middaugh; Heather A Boger
Prenatal LPS increases inflammation in the substantia nigra of Gdnf heterozygous mice.
Brain pathology (Zurich, Switzerland) 2011;21(3):330-48.
2011: Heather A Boger; P Mannangatti; Devadoss J Samuvel; A J Saylor; T S Bender; Jacqueline McGinty; A M Fortress; Vandana Zaman; Peng Huang; Lawrence D Middaugh; Patrick K Randall; Lankupalle D Jayanthi; Baerbel Rohrer; K L Helke; Ann-Charlotte E. Granholm-Bentley; Sammanda Ramamoorthy
Effects of brain-derived neurotrophic factor on dopaminergic function and motor behavior during aging.
Genes, brain, and behavior 2011;10(2):186-98.
2010: William C Griffin; Andrew J Novak; Lawrence D Middaugh; Kennerly S Patrick
The interactive effects of methylphenidate and ethanol on ethanol consumption and locomotor activity in mice.
Pharmacology, biochemistry, and behavior 2010;95(3):267-72.
2010: Heather A Boger; Ann-Charlotte E. Granholm-Bentley; Jacqueline F McGinty; Lawrence D Middaugh
A dual-hit animal model for age-related parkinsonism.
Progress in neurobiology 2010;90(2):217-29.
2009: Heather A Boger; Lawrence D Middaugh; Ann-Charlotte E. Granholm-Bentley; Jacqueline McGinty
Minocycline restores striatal tyrosine hydroxylase in GDNF heterozygous mice but not in methamphetamine-treated mice.
Neurobiology of disease 2009;33(3):459-66.
2009: William C Griffin; Marcelo F Lopez; Amy B Yanke; Lawrence D Middaugh; Howard C Becker
Repeated cycles of chronic intermittent ethanol exposure in mice increases voluntary ethanol drinking and ethanol concentrations in the nucleus accumbens.
Psychopharmacology 2009;201(4):569-80.
2008: Heather A Boger; Lawrence D Middaugh; Vandana Zaman; Barry Hoffer; Ann-Charlotte E. Granholm-Bentley
Differential effects of the dopamine neurotoxin MPTP in animals with a partial deletion of the GDNF receptor, GFR alpha1, gene.
Brain research 2008;1241():18-28.
2008: Vandana Zaman; Heather A Boger; Ann-Charlotte E. Granholm-Bentley; Baerbel Rohrer; Alfred Moore; Mona C. Buhusi; Greg A Gerhardt; Barry Hoffer; Lawrence D Middaugh
The nigrostriatal dopamine system of aging GFRalpha-1 heterozygous mice: neurochemistry, morphology and behavior.
The European journal of neuroscience 2008;28(8):1557-68.
2007: Heather A Boger; Lawrence D Middaugh; Kennerly S Patrick; Sammanda Ramamoorthy; Emily D Denehy; Hao-Jie Zhu; Alejandra M Pacchioni; Ann-Charlotte E. Granholm-Bentley; Jacqueline McGinty
Long-term consequences of methamphetamine exposure in young adults are exacerbated in glial cell line-derived neurotrophic factor heterozygous mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(33):8816-25.
2007: William C Griffin; Patrick K Randall; Lawrence D Middaugh
Intravenous cocaine self-administration: individual differences in male and female C57BL/6J mice.
Pharmacology, biochemistry, and behavior 2007;87(2):267-79.
2007: Jennifer Cook-Easterwood; Lawrence D Middaugh; William C Griffin; Irfan Khan; William R Tyor
Highly active antiretroviral therapy of cognitive dysfunction and neuronal abnormalities in SCID mice with HIV encephalitis.
Experimental neurology 2007;205(2):506-12.
2007: William C Griffin; Lawrence D Middaugh; Howard C Becker
Voluntary ethanol drinking in mice and ethanol concentrations in the nucleus accumbens.
Brain research 2007;1138():208-13.
2007: Shaun Nguyen; Robert Malcolm; Lawrence D Middaugh
Topiramate reduces ethanol consumption by C57BL/6 mice.
Synapse (New York, N.Y.) 2007;61(3):150-6.
2007: William C Griffin; Lawrence D Middaugh; William R Tyor
Chronic cocaine exposure in the SCID mouse model of HIV encephalitis.
Brain research 2007;1134(1):214-9.
2007: Robin L Williard; Lawrence D Middaugh; Hao-Jie Zhu; Kennerly S Patrick
Methylphenidate and its ethanol transesterification metabolite ethylphenidate: brain disposition, monoamine transporters and motor activity.
Behavioural pharmacology 2007;18(1):39-51.
2006: Roberto I Melendez; Lawrence D Middaugh; Peter W Kalivas
Development of an alcohol deprivation and escalation effect in C57BL/6J mice.
Alcoholism, clinical and experimental research 2006;30(12):2017-25.
2006: Heather A Boger; Lawrence D Middaugh; Peng Huang; Vandana Zaman; Alison C Smith; Barry Hoffer; Andreas C Tomac; Ann-Charlotte E. Granholm-Bentley
A partial GDNF depletion leads to earlier age-related deterioration of motor function and tyrosine hydroxylase expression in the substantia nigra.
Experimental neurology 2006;202(2):336-47.
2006: Kevin D Lominac; Zuzana Kapasova; Reem A Hannun; Cole Patterson; Lawrence D Middaugh; Karen K Szumlinski
Behavioral and neurochemical interactions between Group 1 mGluR antagonists and ethanol: potential insight into their anti-addictive properties.
Drug and alcohol dependence 2006;85(2):142-56.
2006: Hao-Jie Zhu; Jun-Sheng Wang; C Lindsay DeVane; Robin L Williard; Jennifer L Donovan; Lawrence D Middaugh; Bryan B Gibson; Kennerly S Patrick; Hao-Jie Zhu
The role of the polymorphic efflux transporter P-glycoprotein on the brain accumulation of d-methylphenidate and d-amphetamine.
Drug metabolism and disposition: the biological fate of chemicals 2006;34(7):1116-21.
2006: Kristine Wiren; Joel G Hashimoto; Paul Alele; Leslie L Devaud; Kimber L Price; Lawrence D Middaugh; Kathleen A Grant; Deborah A Finn
Impact of sex: determination of alcohol neuroadaptation and reinforcement.
Alcoholism, clinical and experimental research 2006;30(2):233-42.
2006: William C Griffin; Lawrence D Middaugh
The influence of sex on extracellular dopamine and locomotor activity in C57BL/6J mice before and after acute cocaine challenge.
Synapse (New York, N.Y.) 2006;59(2):74-81.
2006: William C Griffin; Heather A Boger; Ann-Charlotte E. Granholm-Bentley; Lawrence D Middaugh
Partial deletion of glial cell line-derived neurotrophic factor (GDNF) in mice: Effects on sucrose reward and striatal GDNF concentrations.
Brain research 2006;1068(1):257-60.
2005: Karen K Szumlinski; Kevin D Lominac; Erik Oleson; Jennifer K Walker; Ashley Mason; Marlin H Dehoff; Matthias Klugmann; Matthias Klugman; Stephanie Cagle; Kristine Welt; Matthew J During; Paul F Worley; Lawrence D Middaugh; Peter W Kalivas
Homer2 is necessary for EtOH-induced neuroplasticity.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(30):7054-61.
2005: Karen K Szumlinski; Kevin D Lominac; Kelly A Frys; Lawrence D Middaugh
Genetic variation in heroin-induced changes in behaviour: effects of B6 strain dose on conditioned reward and locomotor sensitization in 129-B6 hybrid mice.
Genes, brain, and behavior 2005;4(5):324-36.
2005: Jennifer E Cook; Somsankar Dasgupta; Lawrence D Middaugh; Elaine C Terry; Paul R Gorry; Steven L Wesselingh; William R Tyor
Highly active antiretroviral therapy and human immunodeficiency virus encephalitis.
Annals of neurology 2005;57(6):795-803.
2005: Shaun Nguyen; Christopher P Deleon; Robert Malcolm; Lawrence D Middaugh
Tiagabine reduces ethanol reward in C57BL/6 mice under acute and chronic administration regimens.
Synapse (New York, N.Y.) 2005;56(3):135-46.
2005: Kennerly S Patrick; Robin L Williard; Adam L VanWert; Justin J Dowd; John E Oatis; Lawrence D Middaugh
Synthesis and pharmacology of ethylphenidate enantiomers: the human transesterification metabolite of methylphenidate and ethanol.
Journal of medicinal chemistry 2005;48(8):2876-81.
2004: Kimber L Price; Lawrence D Middaugh
The dopamine D1 antagonist reduces ethanol reward for C57BL/6 mice.
Alcoholism, clinical and experimental research 2004;28(11):1666-75.
2004: Karen K Szumlinski; Marlin H Dehoff; Shin H Kang; Kelly A Frys; Kevin D Lominac; Matthias Klugmann; Jason Rohrer; William C Griffin; Shigenobu Toda; Nicholas Champtiaux; Thomas Berry; Jian Cheng Tu; Stephanie E Shealy; Matthew J During; Lawrence D Middaugh; Paul F Worley; Peter W Kalivas
Homer proteins regulate sensitivity to cocaine.
Neuron 2004;43(3):401-13.
2004: Howard C Becker; Alicia M Crissman; Shannon Studders; Brian M Kelley; Lawrence D Middaugh
Differential neurosensitivity to the discriminative stimulus properties of ethanol in C57BL/6J and C3H/He mice.
Alcoholism, clinical and experimental research 2004;28(5):712-9.
2004: William C Griffin; Lawrence D Middaugh; Jennifer E Cook; William R Tyor
The severe combined immunodeficient (SCID) mouse model of human immunodeficiency virus encephalitis: deficits in cognitive function.
Journal of neurovirology 2004;10(2):109-15.
2003: Lawrence D Middaugh; Karen K Szumlinski; Yancy Van Patten; Angela-Leigh Bandy Marlowe; Peter W Kalivas
Chronic ethanol consumption by C57BL/6 mice promotes tolerance to its interoceptive cues and increases extracellular dopamine, an effect blocked by naltrexone.
Alcoholism, clinical and experimental research 2003;27(12):1892-900.
2003: William C Griffin; Lawrence D Middaugh
Acquisition of lever pressing for cocaine in C57BL/6J mice: effects of prior Pavlovian conditioning.
Pharmacology, biochemistry, and behavior 2003;76(3-4):543-9.
2003: Lawrence D Middaugh; Diana L Dow-Edwards; Abby A Li; J David Sandler; Jennifer Seed; Larry P Sheets; Dana L Shuey; William Slikker; Walter P Weisenburger; L David Wise; Murray R Selwyn
Neurobehavioral assessment: a survey of use and value in safety assessment studies.
Toxicological sciences : an official journal of the Society of Toxicology 2003;76(2):250-61.
2003: Karen K Szumlinski; Shigenobu Toda; Lawrence D Middaugh; Paul F Worley; Peter W Kalivas
Evidence for a relationship between Group 1 mGluR hypofunction and increased cocaine and ethanol sensitivity in Homer2 null mutant mice.
Annals of the New York Academy of Sciences 2003;1003():468-71.
2003: Rita A Fuchs; Ronald E See; Lawrence D Middaugh
Conditioned stimulus-induced reinstatement of extinguished cocaine seeking in C57BL/6 mice: a mouse model of drug relapse.
Brain research 2003;973(1):99-106.
2003: Himanshu P Upadhyaya; Kathleen T Brady; Jason Liao; Gopalan Sethuraman; Lawrence D Middaugh; Mollie Wharton; Floyd R Sallee
Neuroendocrine and behavioral responses to dopaminergic agonists in adolescents with alcohol abuse.
Psychopharmacology 2003;166(2):95-101.
2003: Vandana Zaman; Z Li; Lawrence D Middaugh; Sammanda Ramamoorthy; Baerbel Rohrer; Matthew E Nelson; Andreas C Tomac; Barry Hoffer; Greg A Gerhardt; Ann-Charlotte E. Granholm-Bentley
The noradrenergic system of aged GDNF heterozygous mice.
Cell transplantation 2003;12(3):291-303.
2002: Karen K Szumlinski; Kimber L Price; Kelly A Frys; Lawrence D Middaugh
Unconditioned and conditioned factors contribute to the 'reinstatement' of cocaine place conditioning following extinction in C57BL/6 mice.
Behavioural brain research 2002;136(1):151-60.
2000: Lawrence D Middaugh; AL Bandy
Naltrexone effects on ethanol consumption and response to ethanol conditioned cues in C57BL/6 mice.
Psychopharmacology 2000;151(4):321-7.
2000: Lawrence D Middaugh; A M Lee; AL Bandy
Ethanol reinforcement in nondeprived mice: effects of abstinence and naltrexone.
Alcoholism, clinical and experimental research 2000;24(8):1172-9.
2000: Lawrence D Middaugh; Brian M Kelley; CH Groseclose; E R Cuison
Delta-opioid and 5-HT3 receptor antagonist effects on ethanol reward and discrimination in C57BL/6 mice.
Pharmacology, biochemistry, and behavior 2000;65(1):145-54.
1999: C Nocjar; Lawrence D Middaugh; M Tavernetti
Ethanol consumption and place-preference conditioning in the alcohol-preferring C57BL/6 mouse: relationship with motor activity patterns.
Alcoholism, clinical and experimental research 1999;23(4):683-92.
1999: Lawrence D Middaugh; Brian M Kelley
Operant ethanol reward in C57BL/6 mice: influence of gender and procedural variables.
Alcohol (Fayetteville, N.Y.) 1999;17(3):185-94.
1999: Lawrence D Middaugh; Brian M Kelley; AL Bandy; K K McGroarty
Ethanol consumption by C57BL/6 mice: influence of gender and procedural variables.
Alcohol (Fayetteville, N.Y.) 1999;17(3):175-83.
1999: William R Tyor; Lawrence D Middaugh
Do alcohol and cocaine abuse alter the course of HIV-associated dementia complex?
Journal of leukocyte biology 1999;65(4):475-81.
1999: Lawrence D Middaugh; Brian M Kelley; E R Cuison; CH Groseclose
Naltrexone effects on ethanol reward and discrimination in C57BL/6 mice.
Alcoholism, clinical and experimental research 1999;23(3):456-64.
1999: B M Kelley; Lawrence D Middaugh
Periadolescent nicotine exposure reduces cocaine reward in adult mice.
Journal of addictive diseases 1999;18(3):27-39.
1998: Nicholas Avgeropoulos; B Kelley; Lawrence D Middaugh; SJ Arrigo; Yuri Persidsky; Howard Gendelman; William R Tyor
SCID mice with HIV encephalitis develop behavioral abnormalities.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1998;18(1):13-20.
1998: Lawrence D Middaugh; K K McGroarty; CH Groseclose; B Adinoff
Cocaine discrimination: relationship to local anesthetics and monoamine uptake inhibitors in C57BL/6 mice.
Psychopharmacology 1998;136(1):44-9.
1998: CH Groseclose; Robert A Draughn; William R Tyor; Floyd R Sallee; Lawrence D Middaugh
Long-term intracranial cannula stabilization in mice with light cured resin composites.
Journal of neuroscience methods 1998;79(1):31-6.
1997: Brian M Kelley; AL Bandy; Lawrence D Middaugh
A study examining intravenous ethanol-conditioned place preference in C57BL/6J mice.
Alcoholism, clinical and experimental research 1997;21(9):1661-6.
1997: Brian M Kelley; CH Groseclose; Lawrence D Middaugh
Prenatal cocaine exposure increases the reinforcing strength of oral ethanol in C57 mice.
Neurotoxicology and teratology 1997;19(5):391-8.
1997: Sanja Altman-Hamamdzic; CH Groseclose; J X Ma; Damir Hamamdzic; NS Vrindavanam; Lawrence D Middaugh; N P Parratto; Floyd R Sallee
Expression of beta-galactosidase in mouse brain: utilization of a novel nonreplicative Sindbis virus vector as a neuronal gene delivery system.
Gene therapy 1997;4(8):815-22.
1997: Brian M Kelley; AL Bandy; Lawrence D Middaugh
A novel chronic and detachable indwelling jugular catheterization procedure for mice.
Physiology & behavior 1997;62(1):163-7.
1997: W Xu; F Bai; C M Tummalapalli; D D Miller; Lawrence D Middaugh; W O Boggan
The interactive effects of cocaine/gender on immune function in mice. An observation of in vivo acute cocaine exposure.
International journal of immunopharmacology 1997;19(6):333-40.
1997: J P Halberda; Lawrence D Middaugh; B E Gard; B P Jackson
DAD1- and DAD2-like agonist effects on motor activity of C57 mice: differences compared to rats.
Synapse (New York, N.Y.) 1997;26(1):81-92.
1997: CH Groseclose; Lawrence D Middaugh
The discrimination and durability of an ethanol cue in young and mid-aged female mice.
Alcohol (Fayetteville, N.Y.) 1997;14(2):191-7.
1996: Brian M Kelley; Lawrence D Middaugh
Ethanol self-administration and motor deficits in adults C57BL/6J mice exposed prenatally to cocaine.
Pharmacology, biochemistry, and behavior 1996;55(4):575-84.
1996: Lawrence D Middaugh; W O Boggan; S A Bingel; Kennerly S Patrick; W Xu
A murine model of prenatal cocaine exposure: effects on the mother and the fetus.
Pharmacology, biochemistry, and behavior 1996;55(4):565-74.
1996: S R Miller; Lawrence D Middaugh; W O Boggan; Kennerly S Patrick
Cocaine concentrations in fetal C57BL/6 mouse brain relative to maternal brain and plasma.
Neurotoxicology and teratology 1996;18(6):645-9.
1996: Lawrence D Middaugh; R Nussbaum; A Ludwicka; Marcy B Bolster; Richard M Silver
Cognitive deficits in a murine model of the eosinophilia-myalgia syndrome: a preliminary report.
Neurotoxicology and teratology 1996;18(5):595-601.
1996: W Xu; William R Tyor; Lawrence D Middaugh; W O Boggan
Cocaine/sex type effects on T lymphocytes: a preliminary report.
Drug and chemical toxicology 1996;19(1-2):109-19.
1996: W O Boggan; W Xu; C L Shepherd; Lawrence D Middaugh
Effects of prenatal ethanol exposure on dopamine systems in C57BL/6J mice.
Neurotoxicology and teratology 1996;18(1):41-8.
1995: G D Gentry; C J Merritt; Lawrence D Middaugh
Effects of prenatal maternal ethanol on male offspring progressive-ratio performance and response to amphetamine.
Neurotoxicology and teratology 1995;17(6):673-7.
1995: Lawrence D Middaugh; W O Boggan
Perinatal maternal ethanol effects on pregnant mice and on offspring viability and growth: influences of exposure time and weaning diet.
Alcoholism, clinical and experimental research 1995;19(5):1351-8.
1994: Lawrence D Middaugh; W O Boggan; C L Shepherd
Prenatal ethanol effects and dopamine systems of adult C57 male mice.
Neurotoxicology and teratology 1994;16(2):207-12.
1993: Kennerly S Patrick; W O Boggan; S R Miller; Lawrence D Middaugh
Gas chromatographic-mass spectrometric determination of plasma and brain cocaine in mice.
Journal of chromatography 1993;621(1):89-94.
1992: Lawrence D Middaugh; K Bao; C L Shepherd
Comparative effects of ethanol on motor activity and operant behavior.
Pharmacology, biochemistry, and behavior 1992;43(2):625-9.
1992: Lawrence D Middaugh; G D Gentry
Prenatal ethanol effects on reward efficacy for adult mice are gestation stage specific.
Neurotoxicology and teratology 1992;14(5):365-70.
1992: R L Hale; Carrie L Randall; Howard C Becker; Lawrence D Middaugh
The effect of prenatal ethanol exposure on scentmarking in the C57BL/6J and C3H/He mouse strains.
Alcohol (Fayetteville, N.Y.) 1992;9(4):287-92.
1992: Lawrence D Middaugh; W F Frackelton; W O Boggan; A Onofrio; C L Shepherd
Gender differences in the effects of ethanol on C57BL/6 mice.
Alcohol (Fayetteville, N.Y.) 1992;9(3):257-60.
1992: K Bao; Lawrence D Middaugh; Howard C Becker; C L Shepherd
Effects of Ro 15-4513 and ethanol on operant behavior of male and female C57BL/6 mice.
Alcohol (Fayetteville, N.Y.) 1992;9(3):193-8.
1991: Lawrence D Middaugh; W O Boggan
Postnatal growth deficits in prenatal ethanol-exposed mice: characteristics and critical periods.
Alcoholism, clinical and experimental research 1991;15(6):919-26.
1991: Lawrence D Middaugh; K Bao; Howard C Becker; S S Daniel
Effects of Ro 15-4513 on ethanol discrimination in C57BL/6 mice.
Pharmacology, biochemistry, and behavior 1991;38(4):763-7.
1990: J Adams; C V Vorhees; Lawrence D Middaugh
Developmental neurotoxicity of anticonvulsants: human and animal evidence on phenytoin.
Neurotoxicology and teratology 1990;12(3):203-14.
1989: Lawrence D Middaugh; J P Favara; W O Boggan
Ethanol stimulation after chronic exposure in C57 mice.
Pharmacology, biochemistry, and behavior 1989;34(2):331-5.
1989: W Boggan; Lawrence D Middaugh
Effect of central injection of phencyclidine on QNB accumulation and motor activity.
European journal of pharmacology 1989;166(2):123-9.
1989: W O Boggan; Lawrence D Middaugh; K Faught
Effect of dopaminergic drugs on enhancement of the binding of quinuclidinyl benzilate by phencyclidine in vivo.
Neuropharmacology 1989;28(6):617-24.
1989: W O Boggan; B Monroe; W R Turner; J Upshur; Lawrence D Middaugh
Effect of prenatal ethanol administration on the urogenital system of mice.
Alcoholism, clinical and experimental research 1989;13(2):206-8.
1989: Lawrence D Middaugh
Prenatal amphetamine effects on behavior: possible mediation by brain monoamines.
Annals of the New York Academy of Sciences 1989;562():308-18.
1988: Lawrence D Middaugh; K L Ayers
Effects of ethanol on mature offspring of mice given ethanol during pregnancy.
Alcoholism, clinical and experimental research 1988;12(3):388-93.
1988: W O Boggan; K Faught; S Boyd; Lawrence D Middaugh
Parametric studies on phencyclidine enhancement of 3H quinuclidinyl benzilate accumulation in vivo.
Pharmacology, biochemistry, and behavior 1988;30(1):31-5.
1988: Lawrence D Middaugh; Carrie L Randall; J P Favara
Prenatal ethanol exposure in C57 mice: effects on pregnancy and offspring development.
Neurotoxicology and teratology 1988;10(2):175-80.
1988: G D Gentry; Lawrence D Middaugh
Prenatal ethanol weakens the efficacy of reinforcers for adult mice.
Teratology 1988;37(2):135-44.
1988: W H Frackelton; Lawrence D Middaugh
Automated acquisition and analysis of animal behavior data utilizing an Apple IIe.
Physiology & behavior 1988;43(2):253-7.
1988: Lawrence D Middaugh; J P Favara; W O Boggan; A J Stringer
Discriminative properties of phencyclidine in mice: generalization to ketamine and monohydroxy metabolites.
Psychopharmacology 1988;96(3):381-4.
1987: N S Buckholtz; Lawrence D Middaugh
Effects of caffeine and L-phenylisopropyladenosine on locomotor activity of mice.
Pharmacology, biochemistry, and behavior 1987;28(2):179-85.
1987: Lawrence D Middaugh; W O Boggan; Carrie L Randall
Stimulatory effects of ethanol in C57BL/6 mice.
Pharmacology, biochemistry, and behavior 1987;27(3):421-4.
1987: W O Boggan; A J Stringer; K Faught; Lawrence D Middaugh
Effect of phencyclidine and two monohydroxy metabolites on 3H QNB binding in vivo in rats.
Pharmacology, biochemistry, and behavior 1987;26(4):847-9.
1987: W O Boggan; Lawrence D Middaugh
Doubtful role for phencyclidine metabolites in PCP enhancement of QNB binding.
Pharmacology, biochemistry, and behavior 1987;26(4):671-6.
1986: Lawrence D Middaugh
Phenobarbital during pregnancy in mouse and man.
Neurotoxicology 1986;7(2):287-301.
1985: Lawrence D Middaugh; J W Zemp
Dopaminergic mediation of long-term behavioral effects of in utero drug exposure.
Neurobehavioral toxicology and teratology 1985;7(6):685-9.
1985: N S Buckholtz; D X Freedman; Lawrence D Middaugh
Daily LSD administration selectively decreases serotonin2 receptor binding in rat brain.
European journal of pharmacology 1985;109(3):421-5.
1985: Carrie L Randall; Howard C Becker; Lawrence D Middaugh
Effect of prenatal ethanol exposure on activity and shuttle avoidance behavior in adult C57 mice.
Alcohol and drug research 1985;6(5):351-60.
1983: Lawrence D Middaugh; J W Zemp; W O Boggan
Pregnancy increases reactivity of mice to phenobarbital.
Science (New York, N.Y.) 1983;220(4596):534-6.
1983: Lawrence D Middaugh; I M Kapetanovic; D J Sweeney; Donald Ingram
Methadone in brain and its effects on locomotor activity of young and aged mice.
Neurobiology of aging 1983;4(4):321-6.
1983: Lawrence D Middaugh; Donald Ingram; Mark A Reynolds
Methadone effects on locomotor activity of young and aged mice.
Neurobiology of aging 1983;4(2):157-61.
1981: Lawrence D Middaugh; L A Blackwell; W O Boggan; J W Zemp
Brain concentrations of phenobarbital and behavioral activation or depression.
Pharmacology, biochemistry, and behavior 1981;15(5):723-8.
1981: Lawrence D Middaugh; L W Simpson; T N Thomas; J W Zemp
Prenatal maternal phenobarbital increases reactivity and retards habituation of mature offspring to environmental stimuli.
Psychopharmacology 1981;74(4):349-52.
1981: Lawrence D Middaugh; T N Thomas; L W Simpson; J W Zemp
Effects of prenatal maternal injections of phenobarbital on brain neurotransmitters and behavior of young C57 mice.
Neurobehavioral toxicology and teratology 1981;3(3):271-5.
1979: L C Tolbert; T N Thomas; Lawrence D Middaugh; J W Zemp
Effect of ascorbic acid on neurochemical, behavioral, and physiological systems mediated by catecholamines.
Life sciences 1979;25(26):2189-95.
1979: W O Boggan; J S Meyer; Lawrence D Middaugh; D L Sparks
Ethanol, calcium, and naloxone in mice.
Alcoholism, clinical and experimental research 1979;3(2):158-61.
1979: Lawrence D Middaugh; W O Boggan; C Wilson-Burrows; J W Zemp
Prenatal maternal phenobarbital alters plasma concentrations of corticosterone in developing offspring.
Life sciences 1979;24(11):999-1002.
1979: L C Tolbert; T N Thomas; Lawrence D Middaugh; J W Zemp
Ascorbate blocks amphetamine-induced turning behavior in rats with unilateral nigro-striatal lesions.
Brain research bulletin 1979;4(1):43-8.
1978: Lawrence D Middaugh; E Read; W O Boggan
Effects of naloxone on ethanol induced alterations of locomotor activity in C57BL/6 mice.
Pharmacology, biochemistry, and behavior 1978;9(2):157-60.
1978: Lawrence D Middaugh; C A Santos
Effects of methadone on behavior maintained by fixed ratio reinforcement schedules.
Pharmacology, biochemistry, and behavior 1978;8(5):521-6.
1976: Lawrence D Middaugh; J W Zemp
Effects of methadone on activity and on brain monoamines in two strains of mice.
Pharmacology, biochemistry, and behavior 1976;5(3):367-70.
1976: Lawrence D Middaugh; T A Grover; L A Blackwell; J W Zemp
Neurochemical and behavioral effects of diet related perinatal folic acid restriction.
Pharmacology, biochemistry, and behavior 1976;5(2):129-34.
1975: Lawrence D Middaugh; C A Santos; J W Zemp
Phenobarbital during pregnancy alters operant behavior of offspring in C57BL/6J mice.
Pharmacology, biochemistry, and behavior 1975;3(6):1137-9.
1975: Lawrence D Middaugh; C A Santos; J W Zemp
Effects of phenobarbital given to pregnant mice on behavior of mature offspring.
Developmental psychobiology 1975;8(4):305-13.
1975: J W Zemp; Lawrence D Middaugh
Some effects of prenatal exposure to d-amphetamine sulfate and phenobarbital on developmental neurochemistry and on behavior.
Addictive diseases 1975;2(1-2):307-31.
1974: Lawrence D Middaugh; L A Blackwell; C A Santos; J W Zemp
Effects of d-amphetamine sulfate given to pregnant mice on activity and on catecholamines in the brains of offspring.
Developmental psychobiology 1974;7(5):429-38.
1972: Lawrence D Middaugh; H M Hurwitz; T M Knapp; W Huchinson
The effect of septal lesions in rats on performance of a free-operant avoidance task.
Physiology & behavior 1972;9(1):59-62.