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Kamal Midha

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Jiang Ping Luo; Gordon McKay; Kamal K Midha; Sarvesh C Vashishtha; Edward M Hawes; Jim Fang
In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine.
S Strauch; Ekarat Jantratid; Jennifer B Dressman; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: lamivudine.
S Strauch; Ekarat Jantratid; Jennifer B Dressman; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: mefloquine hydrochloride.

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2011: Jiang Ping Luo; Gordon McKay; Kamal K Midha; Sarvesh C Vashishtha; Edward M Hawes; Jim Fang
In vitro identification of the human cytochrome p450 enzymes involved in the oxidative metabolism of loxapine.
Biopharmaceutics & drug disposition 2011;32(7):398-407.
2011: S Strauch; Ekarat Jantratid; Jennifer B Dressman; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: lamivudine.
Journal of pharmaceutical sciences 2011;100(6):2054-63.
2011: S Strauch; Ekarat Jantratid; Jennifer B Dressman; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: mefloquine hydrochloride.
Journal of pharmaceutical sciences 2011;100(1):11-21.
2010: Ekarat Jantratid; S Strauch; C Becker; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: Doxycycline hyclate.
Journal of pharmaceutical sciences 2010;99(4):1639-53.
2009: C Becker; Jennifer B Dressman; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: rifampicin.
Journal of pharmaceutical sciences 2009;98(7):2252-67.
2008: J Arnal; I Gonzalez-Alvarez; Marival Bermejo; Gordon L Amidon; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; S Stavchansky; J B Dressman; D M Barends
Biowaiver monographs for immediate release solid oral dosage forms: aciclovir.
Journal of pharmaceutical sciences 2008;97(12):5061-73.
2008: C Becker; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: pyrazinamide.
Journal of pharmaceutical sciences 2008;97(9):3709-20.
2008: C Becker; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: ethambutol dihydrochloride.
Journal of pharmaceutical sciences 2008;97(4):1350-60.
2007: M Vogt; Hartmut Derendorf; J Krämer; Hans E Junginger; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Jennifer B Dressman; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: prednisone.
Journal of pharmaceutical sciences 2007;96(6):1480-9.
2007: Kamal K Midha; Vinod P Shah; Gur Jai Pal Singh; Rabi Patnaik
Conference report: Bio-International 2005.
Journal of pharmaceutical sciences 2007;96(4):747-54.
2007: C Becker; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; S Kopp; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: isoniazid.
Journal of pharmaceutical sciences 2007;96(3):522-31.
2007: M Vogt; Hartmut Derendorf; J Krämer; Hans E Junginger; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Jennifer B Dressman; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: prednisolone.
Journal of pharmaceutical sciences 2007;96(1):27-37.
2006: Martin H Teicher; Ann Polcari; Mary Foley; Elizabeth Valente; Cynthia E McGreenery; Wei-Wei Chang; Gordon McKay; Kamal K Midha
Methylphenidate blood levels and therapeutic response in children with attention-deficit hyperactivity disorder: I. Effects of different dosing regimens.
Journal of child and adolescent psychopharmacology 2006;16(4):416-31.
2006: Ekarat Jantratid; Sompol Prakongpan; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; Kamal K Midha; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: cimetidine.
Journal of pharmaceutical sciences 2006;95(5):974-84.
2006: Lida Kalantzi; Christos Reppas; Jennifer B Dressman; Gordon L Amidon; Hans E Junginger; Kamal K Midha; Vinod P Shah; Salomon Stavchansky; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: acetaminophen (paracetamol).
Journal of pharmaceutical sciences 2006;95(1):4-14.
2005: Kamal K Midha; Maureen J Rawson; John W Hubbard
The bioequivalence of highly variable drugs and drug products.
International journal of clinical pharmacology and therapeutics 2005;43(10):485-98.
2005: H Potthast; Jennifer B Dressman; Hans E Junginger; Kamal K Midha; H Oeser; Vinod P Shah; H Vogelpoel; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: ibuprofen.
Journal of pharmaceutical sciences 2005;94(10):2121-31.
2005: Hanna Kortejärvi; Marjo Yliperttula; Jennifer B Dressman; Hans E Junginger; Kamal K Midha; Vinod P Shah; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms: ranitidine hydrochloride.
Journal of pharmaceutical sciences 2005;94(8):1617-25.
2005: R K Verbeeck; Hans E Junginger; Kamal K Midha; Vinod P Shah; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: chloroquine phosphate, chloroquine sulfate, and chloroquine hydrochloride.
Journal of pharmaceutical sciences 2005;94(7):1389-95.
2005: Kamal K Midha; Maureen J Rawson; Gordon McKay; John W Hubbard
Exposure measures applied to the bioequivalence of two sustained release formulations of bupropion.
International journal of clinical pharmacology and therapeutics 2005;43(5):244-54.
2004: Kamal K Midha; Maureen J Rawson; John W Hubbard
The role of metabolites in bioequivalence.
Pharmaceutical research 2004;21(8):1331-44.
2004: H Vogelpoel; J Welink; Gordon L Amidon; Hans E Junginger; Kamal K Midha; H Möller; M Olling; Vinod P Shah; Dirk M Barends
Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: verapamil hydrochloride, propranolol hydrochloride, and atenolol.
Journal of pharmaceutical sciences 2004;93(8):1945-56.
2004: Nehal A Kasim; Marc Whitehouse; Chandrasekharan Ramachandran; Marival Bermejo; Hans Lennernäs; Ajaz Hussain; Hans E Junginger; Salomon Stavchansky; Kamal K Midha; Vinod P Shah; Gordon L Amidon
Molecular properties of WHO essential drugs and provisional biopharmaceutical classification.
Molecular pharmaceutics 2004;1(1):85-96.
2003: László Tóthfalusi; Laszlo Endrenyi; Kamal K Midha
Scaling or wider bioequivalence limits for highly variable drugs and for the special case of C(max).
International journal of clinical pharmacology and therapeutics 2003;41(5):217-25.
2002: J-H Yan; John W Hubbard; Gordon McKay; E D Korchinski; Kamal K Midha
Absolute bioavailability and stereoselective pharmacokinetics of doxepin.
Xenobiotica; the fate of foreign compounds in biological systems 2002;32(7):615-23.
2001: J Fang; Gordon McKay; J Song; A Remillrd; X Li; Kamal K Midha
In vitro characterization of the metabolism of haloperidol using recombinant cytochrome p450 enzymes and human liver microsomes.
Drug metabolism and disposition: the biological fate of chemicals 2001;29(12):1638-43.
2001: Kamal K Midha; Gordon McKay; Maureen J Rawson; E D Korchinski; John W Hubbard
Effects of food on the pharmacokinetics of methylphenidate.
Pharmaceutical research 2001;18(8):1185-9.
2001: László Tóthfalusi; Laszlo Endrenyi; Kamal K Midha; Maureen J Rawson; John W Hubbard
Evaluation of the bioequivalence of highly-variable drugs and drug products.
Pharmaceutical research 2001;18(6):728-33.
2000: Vinod P Shah; Kamal K Midha; J W Findlay; H M Hill; J D Hulse; I J McGilveray; G McKay; K J Miller; Rabi Patnaik; M L Powell; A Tonelli; C T Viswanathan; A Yacobi
Bioanalytical method validation--a revisit with a decade of progress.
Pharmaceutical research 2000;17(12):1551-7.
2000: J Fang; Gordon McKay; John W Hubbard; Edward M Hawes; Kamal K Midha
Dose staggering as a strategy to reduce drug--drug interactions due to reversible enzyme inhibition between orally administered drugs with high first pass effect: a computer simulation study.
Biopharmaceutics & drug disposition 2000;21(7):249-59.
1999: Kamal K Midha; Maureen J Rawson; John W Hubbard
Prescribability and switchability of highly variable drugs and drug products.
Journal of controlled release : official journal of the Controlled Release Society 1999;62(1-2):33-40.
1999: Kamal K Midha; John W Hubbard; Gordon McKay; Maureen J Rawson; D Hsia
The role of metabolites in a bioequivalence study II: amoxapine, 7-hydroxyamoxapine, and 8-hydroxyamoxapine.
International journal of clinical pharmacology and therapeutics 1999;37(9):428-38.
1999: John W Hubbard; S Hadad; JP Luo; Gordon McKay; Kamal K Midha
Pharmacokinetics of fluphenazine, a highly lipophilic drug, estimated from a pulse dose of a stable isotopomer in dogs at steady state.
Journal of pharmaceutical sciences 1999;88(9):918-21.
1999: M Tugnait; Edward M Hawes; Gordon McKay; M Eichelbaum; Kamal K Midha
Characterization of the human hepatic cytochromes P450 involved in the in vitro oxidation of clozapine.
Chemico-biological interactions 1999;118(2):171-89.
1998: Laszlo Endrenyi; Kamal K Midha
Individual bioequivalence--has its time come?
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1998;6(4):271-8.
1998: S A Qureshi; M Jiang; Kamal K Midha; J P Skelly
In vitro evaluation of percutaneous absorption of an acyclovir product using intact and tape-stripped human skin.
Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Société canadienne des sciences pharmaceutiques 1998;1(3):102-7.
1998: JP Luo; John W Hubbard; Kamal K Midha
The roles of depot injection sites and proximal lymph nodes in the presystemic absorption of fluphenazine decanoate and fluphenazine: ex vivo experiments in rats.
Pharmaceutical research 1998;15(9):1485-9.
1998: Laszlo Endrenyi; Gordon L Amidon; Kamal K Midha; J P Skelly
Individual bioequivalence: attractive in principle, difficult in practice.
Pharmaceutical research 1998;15(9):1321-5.
1998: Kamal K Midha; Gordon McKay; Maureen J Rawson; John W Hubbard
The impact of stereoisomerism in bioequivalence studies.
Journal of pharmaceutical sciences 1998;87(7):797-802.
1998: Kamal K Midha; Maureen J Rawson; John W Hubbard
Bioequivalence: switchability and scaling.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1998;6(2):87-91.
1997: Kamal K Midha; Maureen J Rawson; John W Hubbard
Bioequivalence: issues and options.
Journal of pharmacokinetics and biopharmaceutics 1997;25(6):743-52.
1997: J H Yan; John W Hubbard; Gordon McKay; Kamal K Midha
Stereoselective in vivo and in vitro studies on the metabolism of doxepin and N-desmethyldoxepin.
Xenobiotica; the fate of foreign compounds in biological systems 1997;27(12):1245-57.
1997: Kamal K Midha; Maureen J Rawson; John W Hubbard
Individual and average bioequivalence of highly variable drugs and drug products.
Journal of pharmaceutical sciences 1997;86(11):1193-7.
1997: JP Luo; John W Hubbard; Kamal K Midha
Studies on the mechanism of absorption of depot neuroleptics: fluphenazine decanoate in sesame oil.
Pharmaceutical research 1997;14(8):1079-84.
1997: M Tugnait; Edward M Hawes; Gordon McKay; Allan E Rettie; Robert L Haining; Kamal K Midha
N-oxygenation of clozapine by flavin-containing monooxygenase.
Drug metabolism and disposition: the biological fate of chemicals 1997;25(4):524-7.
1997: J Yan; John W Hubbard; Gordon McKay; Kamal K Midha
Stereoselective and simultaneous measurement of cis- and trans-isomers of doxepin and N-desmethyldoxepin in plasma or urine by high-performance liquid chromatography.
Journal of chromatography. B, Biomedical sciences and applications 1997;691(1):131-8.
1997: JP Luo; John W Hubbard; Kamal K Midha
Sensitive method for the simultaneous measurement of fluphenazine decanoate and fluphenazine in plasma by high-performance liquid chromatography with coulometric detection.
Journal of chromatography. B, Biomedical sciences and applications 1997;688(2):303-8.
1996: G O Zhang; Gordon McKay; John W Hubbard; Kamal K Midha
Application of electrospray mass spectrometry in the identification of intact glucuronide and suplate conjugates of clozapine in rat.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(5):541-50.
1996: G Muralidharan; J K Cooper; Edward M Hawes; E D Korchinski; Kamal K Midha
Quinidine inhibits the 7-hydroxylation of chlorpromazine in extensive metabolisers of debrisoquine.
European journal of clinical pharmacology 1996;50(1-2):121-8.
1995: S Hadad; John W Hubbard; Gordon McKay; Edward M Hawes; S Shrikhande; Kamal K Midha
Evidence for the lack of a human metabolic isotope effect of a deuterium analog of fluphenazine.
Pharmaceutical research 1995;12(9):1388-90.
1995: H He; Gordon McKay; Kamal K Midha
Phase I and II metabolites of benztropine in rat urine and bile.
Xenobiotica; the fate of foreign compounds in biological systems 1995;25(8):857-72.
1995: H He; Gordon McKay; B Wirshing; Kamal K Midha
Development and application of a specific and sensitive radioimmunoassay for trihexyphenidyl to a pharmacokinetic study in humans.
Journal of pharmaceutical sciences 1995;84(5):561-7.
1995: H Luo; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
N(+)-glucuronidation of aliphatic tertiary amines in human: antidepressant versus antipsychotic drugs.
Xenobiotica; the fate of foreign compounds in biological systems 1995;25(3):291-301.
1994: Kamal K Midha; John W Hubbard; Stephen R Marder; BD Marshall; T Van Putten
Impact of clinical pharmacokinetics on neuroleptic therapy in patients with schizophrenia.
Journal of psychiatry & neuroscience : JPN 1994;19(4):254-64.
1994: H Luo; Gordon McKay; Kamal K Midha
Identification of clozapine N(+)-glucuronide in the urine of patients treated with clozapine using electrospray mass spectrometry.
Biological mass spectrometry 1994;23(3):147-8.
1993: John W Hubbard; Kamal K Midha; Edward M Hawes; Gordon McKay; Stephen R Marder; Manickam Aravagiri; E D Korchinski
Metabolism of phenothiazine and butyrophenone antipsychotic drugs. A review of some recent research findings and clinical implications.
The British journal of psychiatry. Supplement 1993;(22):19-24.
1993: H H Blume; Kamal K Midha
Bio-International 92, conference on bioavailability, bioequivalence, and pharmacokinetic studies.
Journal of pharmaceutical sciences 1993;82(11):1186-9.
1993: G Lin; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
Metabolism of piperidine-type phenothiazine antipsychotic agents. IV. Thioridazine in dog, man and rat.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(10):1059-74.
1993: H He; Gordon McKay; Kamal K Midha
Development of a sensitive and specific radioimmunoassay for benztropine.
Journal of pharmaceutical sciences 1993;82(10):1027-32.
1993: Kamal K Midha; Stephen R Marder; T J Jaworski; Gordon McKay; John W Hubbard; Edward M Hawes; T Van Putten; William C Wirshing; Manickam Aravagiri
Clinical perspectives of some neuroleptics through development and application of their assays.
Therapeutic drug monitoring 1993;15(3):179-89.
1993: Kamal K Midha; John W Hubbard; Gordon McKay; Edward M Hawes; D Hsia
The role of metabolites in a bioequivalence study 1: loxapine, 7-hydroxyloxapine and 8-hydroxyloxapine.
International journal of clinical pharmacology, therapy, and toxicology 1993;31(4):177-83.
1993: T J Jaworski; M S Sardessai; Manickam Aravagiri; G Lin; Y Y Shi; Edward M Hawes; John W Hubbard; Gordon McKay; Kamal K Midha
Synthesis of the N-oxides of phenothiazine antipsychotic agents.
Journal of pharmaceutical sciences 1993;82(3):330-3.
1993: Kamal K Midha; E D Ormsby; John W Hubbard; Gordon McKay; Edward M Hawes; L Gavalas; I J McGilveray
Logarithmic transformation in bioequivalence: application with two formulations of perphenazine.
Journal of pharmaceutical sciences 1993;82(2):138-44.
1993: N R Srinivas; John W Hubbard; E D Korchinski; Kamal K Midha
Enantioselective pharmacokinetics of dl-threo-methylphenidate in humans.
Pharmaceutical research 1993;10(1):14-21.
1993: Pollen K F Yeung; John W Hubbard; E D Korchinski; Kamal K Midha
Pharmacokinetics of chlorpromazine and key metabolites.
European journal of clinical pharmacology 1993;45(6):563-9.
1993: G Lin; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
The metabolism of piperidine-type phenothiazine antipsychotic agents. III. Mesoridazine in dog, human and rat.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(1):37-52.
1993: G Lin; Edward M Hawes; Gordon McKay; S F Cooper; E D Korchinski; Kamal K Midha
The metabolism of piperidine-type phenothiazine antipsychotic agents. II. Sulforidazine in dog and human.
Xenobiotica; the fate of foreign compounds in biological systems 1993;23(1):27-36.
1992: H Luo; Edward M Hawes; Gordon McKay; Kamal K Midha
Synthesis and characterization of quaternary ammonium-linked glucuronide metabolites of drugs with an aliphatic tertiary amine group.
Journal of pharmaceutical sciences 1992;81(11):1079-83.
1992: N R Srinivas; John W Hubbard; D Quinn; Kamal K Midha
Enantioselective pharmacokinetics and pharmacodynamics of dl-threo-methylphenidate in children with attention deficit hyperactivity disorder.
Clinical pharmacology and therapeutics 1992;52(5):561-8.
1992: N R Srinivas; John W Hubbard; E D Korchinski; Kamal K Midha
Stereoselective urinary pharmacokinetics of dl-threo-methylphenidate and its major metabolite in humans.
Journal of pharmaceutical sciences 1992;81(8):747-9.
1992: G Lin; Edward M Hawes; Gordon McKay; Kamal K Midha
The metabolism of piperidine-type phenothiazine antipsychotic agents. I. Sulforidazine in the rat.
Xenobiotica; the fate of foreign compounds in biological systems 1992;22(3):303-17.
1992: Kamal K Midha; John W Hubbard; Gordon McKay; Edward M Hawes; E D Korchinski; T Gurnsey; J K Cooper; R Schwede
Stereoselective pharmacokinetics of doxepin isomers.
European journal of clinical pharmacology 1992;42(5):539-44.
1991: T J Jaworski; Edward M Hawes; John W Hubbard; Gordon McKay; Kamal K Midha
The metabolites of chlorpromazine N-oxide in rat bile.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(11):1451-9.
1991: G Muralidharan; Edward M Hawes; Gordon McKay; Kamal K Midha
Quinine is a more potent inhibitor than quinidine in rat of the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(11):1441-50.
1991: Vinod P Shah; Kamal K Midha; S Dighe; I J McGilveray; J P Skelly; A Yacobi; T Layloff; C T Viswanathan; C E Cook; R D McDowall
Analytical methods validation: bioavailability, bioequivalence and pharmacokinetic studies. Conference report.
European journal of drug metabolism and pharmacokinetics 1991;16(4):249-55.
1991: H Luo; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
N(+)-glucuronidation of aliphatic tertiary amines, a general phenomenon in the metabolism of H1-antihistamines in humans.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(10):1281-8.
1991: H Luo; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
The quaternary ammonium-linked glucuronide of doxepin: a major metabolite in depressed patients treated with doxepin.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(3):722-4.
1991: C J Jackson; John W Hubbard; Kamal K Midha
Biosynthesis and characterization of glucuronide metabolites of fluphenazine: 7-hydroxyfluphenazine glucuronide and fluphenazine glucuronide.
Xenobiotica; the fate of foreign compounds in biological systems 1991;21(3):383-93.
1991: N R Srinivas; John W Hubbard; D Quinn; E D Korchinski; Kamal K Midha
Extensive and enantioselective presystemic metabolism of dl-threo-methylphenidate in humans.
Progress in neuro-psychopharmacology & biological psychiatry 1991;15(2):213-20.
1991: N R Srinivas; John W Hubbard; Gordon McKay; Edward M Hawes; Kamal K Midha
In vitro hydrolysis of RR,SS-threo-methylphenidate by blood esterases--differential and enantioselective interspecies variability.
Chirality 1991;3(2):99-103.
1991: G Muralidharan; Edward M Hawes; Gordon McKay; E D Korchinski; Kamal K Midha
Quinidine but not quinine inhibits in man the oxidative metabolic routes of methoxyphenamine which involve debrisoquine 4-hydroxylase.
European journal of clinical pharmacology 1991;41(5):471-4.
1991: C J Jackson; John W Hubbard; Gordon McKay; J K Cooper; Edward M Hawes; Kamal K Midha
Identification of phase-I and phase-II metabolites of fluphenazine in rat bile. Intact glucuronide and sulfate conjugates.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(1):188-93.
1991: Y Z Shu; John W Hubbard; Gordon McKay; Edward M Hawes; Kamal K Midha
Cis-flupentixol metabolites in rat plasma and bile. The first proof of glutathione conjugation at the exocyclic double bond.
Drug metabolism and disposition: the biological fate of chemicals 1991;19(1):154-62.
1990: Y Z Shu; John W Hubbard; Gordon McKay; Kamal K Midha
Identification of phenolic doxepin glucuronides from patient urine and rat bile.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(6):1096-9.
1990: I J McGilveray; Kamal K Midha; J P Skelly; S Dighe; J T Doluisio; I W French; A Karim; R Burford
Consensus report from "Bio International '89": issues in the evaluation of bioavailability data.
Journal of pharmaceutical sciences 1990;79(10):945-6.
1990: N R Srinivas; John W Hubbard; Kamal K Midha
Enantioselective gas chromatographic assay with electron-capture detection for dl-ritalinic acid in plasma.
Journal of chromatography 1990;530(2):327-36.
1990: Y Z Shu; John W Hubbard; J K Cooper; Gordon McKay; E D Korchinski; R Kumar; Kamal K Midha
The identification of urinary metabolites of doxepin in patients.
Drug metabolism and disposition: the biological fate of chemicals 1990;18(5):735-41.
1990: Kamal K Midha; Gordon McKay; B S Chakraborty; M Young; Edward M Hawes; John W Hubbard; J K Cooper; E D Korchinski
Bioequivalence of two thorazine tablet formulations using radioimmunoassay and gas chromatographic-mass spectrometric methods.
Journal of pharmaceutical sciences 1990;79(3):196-201.
1990: Gordon McKay; T Steeves; J K Cooper; Edward M Hawes; Kamal K Midha
Development and application of a radioimmunoassay for fluphenazine based on monoclonal antibodies and its comparison with alternate assay methods.
Journal of pharmaceutical sciences 1990;79(3):240-3.
1990: T J Jaworski; Edward M Hawes; Gordon McKay; Kamal K Midha
The metabolism of chlorpromazine N-oxide in man and dog.
Xenobiotica; the fate of foreign compounds in biological systems 1990;20(1):107-15.
1990: Kamal K Midha; B S Chakraborty; R Schwede; Edward M Hawes; Gordon McKay; John W Hubbard; J K Cooper; M Moore
Comparative bioavailability of two tablet formulations of fluphenazine dihydrochloride in drug-free psychiatric patients.
Journal of pharmaceutical sciences 1990;79(1):3-8.
1989: John W Hubbard; N R Srinivas; D Quinn; Kamal K Midha
Enantioselective aspects of the disposition of dl-threo-methylphenidate after the administration of a sustained-release formulation to children with attention deficit-hyperactivity disorder.
Journal of pharmaceutical sciences 1989;78(11):944-7.
1989: B S Chakraborty; Kamal K Midha; Gordon McKay; Edward M Hawes; John W Hubbard; E D Korchinski; MG Choc; W T Robinson
Single dose kinetics of thioridazine and its two psychoactive metabolites in healthy humans: a dose proportionality study.
Journal of pharmaceutical sciences 1989;78(10):796-801.
1989: Kamal K Midha; B S Chakraborty; R Schwede; Edward M Hawes; John W Hubbard; Gordon McKay
Comparative bioavailability of a new commercial tablet formulation and two lots of a reference formulation of haloperidol.
Journal of pharmaceutical sciences 1989;78(6):443-7.
1989: Kamal K Midha; B S Chakraborty; D A Ganes; Edward M Hawes; John W Hubbard; David Keegan; E D Korchinski; Gordon McKay
Intersubject variation in the pharmacokinetics of haloperidol and reduced haloperidol.
Journal of clinical psychopharmacology 1989;9(2):98-104.
1989: BD Marshall; S M Glynn; Kamal K Midha; John W Hubbard; L L Bowen; L Banzett; Jim Mintz; Robert Paul Liberman
Adverse effects of fenfluramine in treatment refractory schizophrenia.
Journal of clinical psychopharmacology 1989;9(2):110-5.
1989: G Muralidharan; Kamal K Midha; Gordon McKay; Edward M Hawes; T Inaba
Selective in vivo inhibition by quinidine of methoxyphenamine oxidation in rat models of human debrisoquine polymorphism.
Xenobiotica; the fate of foreign compounds in biological systems 1989;19(2):189-97.
1989: Kamal K Midha; Edward M Hawes; John W Hubbard; E D Korchinski; Gordon McKay
Intersubject variation in the pharmacokinetics of chlorpromazine in healthy men.
Journal of clinical psychopharmacology 1989;9(1):4-8.
1989: N R Srinivas; John W Hubbard; Edward M Hawes; Gordon McKay; Kamal K Midha
Enantioselective gas chromatographic assays with electron-capture detection for methoxyphenamine and its three primary metabolites in human urine.
Journal of chromatography 1989;487(1):61-72.
1989: J K Cooper; Edward M Hawes; John W Hubbard; Gordon McKay; Kamal K Midha
An ultrasensitive method for the measurement of fluphenazine in plasma by high-performance liquid chromatography with coulometric detection.
Therapeutic drug monitoring 1989;11(3):354-60.
1989: B S Chakraborty; John W Hubbard; Edward M Hawes; Gordon McKay; J K Cooper; T Gurnsey; E D Korchinski; Kamal K Midha
Interconversion between haloperidol and reduced haloperidol in healthy volunteers.
European journal of clinical pharmacology 1989;37(1):45-8.
1988: N R Srinivas; John W Hubbard; J K Cooper; Kamal K Midha
Enantioselective gas chromatographic assay with electron-capture detection for dl-fenfluramine and dl-norfenfluramine in plasma.
Journal of chromatography 1988;433():105-17.
1988: T J Jaworski; Edward M Hawes; Gordon McKay; Kamal K Midha
The metabolism of chlorpromazine N-oxide in the rat.
Xenobiotica; the fate of foreign compounds in biological systems 1988;18(12):1439-47.
1988: A K Chaudhary; John W Hubbard; Gordon McKay; Kamal K Midha
Identification of a quaternary ammonium-linked glucuronide of chlorpromazine in the urine of a schizophrenic patient treated with chlorpromazine.
Drug metabolism and disposition: the biological fate of chemicals 1988;16(3):506-8.
1988: Kamal K Midha; Edward M Hawes; John W Hubbard; Gordon McKay; G Rauw; M S Sardessai; Manickam Aravagiri; M D Moore
Radioimmunoassay for fluphenazine sulfoxide in human plasma.
Journal of pharmacological methods 1988;19(1):63-74.
1988: Michael J Gitlin; Kamal K Midha; D Fogelson; Keith H Nuechterlein
Persistence of fluphenazine in plasma after decanoate withdrawal.
Journal of clinical psychopharmacology 1988;8(1):53-6.
1988: M B Gupta; John W Hubbard; Kamal K Midha
Separation of enantiomers of derivatised or underivatised propranolol by means of high-performance liquid chromatography.
Journal of chromatography 1988;424(1):189-94.
1988: B S Chakraborty; Edward M Hawes; Kamal K Midha
Development of a radioimmunoassay procedure for sulforidazine and its comparison with a high-performance liquid chromatographic method.
Therapeutic drug monitoring 1988;10(2):205-14.
1988: Kamal K Midha; J K Cooper; Edward M Hawes; John W Hubbard; E D Korchinski; Gordon McKay
An ultrasensitive method for the measurement of haloperidol and reduced haloperidol in plasma by high-performance liquid chromatography with coulometric detection.
Therapeutic drug monitoring 1988;10(2):177-83.
1988: B S Chakraborty; Edward M Hawes; Gordon McKay; John W Hubbard; E D Korchinski; Kamal K Midha; MG Choc; W T Robinson
S-oxidation of thioridazine to psychoactive metabolites: an oral dose-proportionality study in healthy volunteers.
Drug metabolism and drug interactions 1988;6(3-4):425-37.
1988: Kamal K Midha; Edward M Hawes; John W Hubbard; E D Korchinski; Gordon McKay
Variation in the single dose pharmacokinetics of fluphenazine in psychiatric patients.
Psychopharmacology 1988;96(2):206-11.
1988: Kamal K Midha; Edward M Hawes; John W Hubbard; E D Korchinski; Gordon McKay
A pharmacokinetic study of trifluoperazine in two ethnic populations.
Psychopharmacology 1988;95(3):333-8.
1987: D A Ganes; Kamal K Midha
Sensitive and specific high-performance liquid chromatographic assay for the quantification of sulforidazine and two diastereomeric sulforidazine-5-sulfoxide metabolites in plasma.
Journal of chromatography 1987;423():227-37.
1987: B S Chakraborty; Edward M Hawes; Kamal K Midha
Development of a radioimmunoassay procedure for mesoridazine and its comparison with a high-performance liquid chromatographic method.
Therapeutic drug monitoring 1987;9(4):464-71.
1987: Kamal K Midha; John W Hubbard; J K Cooper; T Gurnsey; Edward M Hawes; Gordon McKay; B S Chakraborty; Pollen K F Yeung
Therapeutic monitoring of chlorpromazine. IV: Comparison of a new high-performance liquid chromatographic method with radioimmunoassays for parent drug and some of its major metabolites.
Therapeutic drug monitoring 1987;9(3):358-65.
1987: D A Ganes; Kamal K Midha
Identification in in vivo acetylation pathway for N-dealkylated metabolites of doxylamine in humans.
Xenobiotica; the fate of foreign compounds in biological systems 1987;17(8):993-9.
1987: B S Chakraborty; M S Sardessai; T J Jaworski; Kamal K Midha; Edward M Hawes
Synthesis and properties of haptens for the development of radioimmunoassays for thioridazine, mesoridazine, and sulforidazine.
Pharmaceutical research 1987;4(3):207-13.
1987: N R Srinivas; D Quinn; John W Hubbard; Kamal K Midha
Stereoselective disposition of methylphenidate in children with attention-deficit disorder.
The Journal of pharmacology and experimental therapeutics 1987;241(1):300-6.
1987: Kamal K Midha; John W Hubbard; Stephen R Marder; Edward M Hawes; T Van Putten; Gordon McKay; P R May
The sulfoxidation of fluphenazine in schizophrenic patients maintained on fluphenazine decanoate.
Psychopharmacology 1987;93(3):369-73.
1986: Stephen R Marder; John W Hubbard; T Van Putten; Edward M Hawes; Gordon McKay; Jim Mintz; P R May; Kamal K Midha
Plasma fluphenazine levels in patients receiving two doses of fluphenazine decanoate.
Psychopharmacology bulletin 1986;22(1):264-6.
1986: Stephen R Marder; Edward M Hawes; T Van Putten; John W Hubbard; Gordon McKay; Jim Mintz; P R May; Kamal K Midha
Fluphenazine plasma levels in patients receiving low and conventional doses of fluphenazine decanoate.
Psychopharmacology 1986;88(4):480-3.
1985: John W Hubbard; J K Cooper; Edward M Hawes; D J Jenden; P R May; M Martin; Gordon McKay; T Van Putten; Kamal K Midha
Therapeutic monitoring of chlorpromazine I: Pitfalls in plasma analysis.
Therapeutic drug monitoring 1985;7(2):222-8.
1984: Gordon McKay; G A Rauw; M D Stonkus; R A Dulos; R G Gedir; Edward M Hawes; Kamal K Midha
Radioimmunoassay for trimeprazine in human plasma.
Journal of pharmacological methods 1984;12(3):203-11.
1984: Kamal K Midha; G Rauw; Gordon McKay; J K Cooper; J McVittie
Subnanogram quantitation of chlorpheniramine in plasma by a new radioimmunoassay and comparison with a liquid chromatographic method.
Journal of pharmaceutical sciences 1984;73(8):1144-7.
1984: Edward M Hawes; H U Shetty; J K Cooper; G Rauw; Gordon McKay; Kamal K Midha
Radioimmunoassay for psychotropic drugs. III: Synthesis and properties of haptens for trifluoperazine and fluphenazine.
Journal of pharmaceutical sciences 1984;73(2):247-50.
1983: Kamal K Midha; Edward M Hawes; Gordon McKay; John W Hubbard; E D Korchinski; David Keegan
Plasma concentrations of trifluoperazine following single low doses.
Canadian Medical Association journal 1983;129(4):324.
1983: Edward M Hawes; T S Gurnsey; H U Shetty; Kamal K Midha
Synthesis of deuterium-labeled prochlorperazine.
Journal of pharmaceutical sciences 1983;72(6):702-3.
1983: Kamal K Midha; Edward M Hawes; G Rauw; Gordon McKay; J K Cooper; H U Shetty
Development of radioimmunoassays for trifluoperazine and their application to metabolic studies of the drug.
Journal of pharmacological methods 1983;9(4):283-93.
1983: Kamal K Midha; Edward M Hawes; G Rauw; J McVittie; Gordon McKay; J K Cooper; H U Shetty
Radioimmunoassay for prochlorperazine in human plasma.
Therapeutic drug monitoring 1983;5(1):117-21.
1983: J Dudley; G Rauw; Edward M Hawes; D L Keegan; Kamal K Midha
Correlation of fluphenazine plasma levels versus clinical response in patients: a pilot study.
Progress in neuro-psychopharmacology & biological psychiatry 1983;7(4-6):791-5.
1981: Kamal K Midha; J K Cooper; I J McGilveray; A G Butterfield; John W Hubbard
High-performance liquid chromatographic assay for nanogram determination of chlorpromazine and its comparison with a radioimmunoassay.
Journal of pharmaceutical sciences 1981;70(9):1043-6.