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Patrick Midoux

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Physiology

Devices

Gene Transfer Techniques

Procedures

Flow Cytometry

Living Beings

Mice

Anatomy

Phenomena

Glycosylation

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequence

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Co-Publications
Name
36
Monsigny, Michel
35
Roche, Annie-Claude
27
Pichon, Chantal
11
Mayer, Roger
8
Erbacher, Patrick
8
Gonçalves, Christine
4
Breuzard, Gilles
3
Briand, Pascale
3
Freulon, I
3
Fajac, Isabelle
3
Jaffrès, Paul-Alain
3
Guérin, Brigitte
3
Mennesson, Eric
3
Yaouanc, Jean-Jacques
2
Michael, MOCKEY

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Publications

TOP 3
Delalande Anthony; Bureau Michel-Francis; Midoux Patrick; Bouakaz Ayache; Pichon Chantal
Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy.
Buré Corinne; Pichon Chantal; Midoux Patrick
Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide.
Midoux Patrick; Pichon Chantal; Yaouanc Jean-Jacques; Jaffrès Paul-Alain
Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers.

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All Publications

2010: Delalande Anthony; Bureau Michel-Francis; Midoux Patrick; Bouakaz Ayache; Pichon Chantal
Ultrasound-assisted microbubbles gene transfer in tendons for gene therapy.
Ultrasonics 2010;50(2):269-72.
2009: Buré Corinne; Pichon Chantal; Midoux Patrick
Involvement of histidines 11, 15 and 19 in the binding of zinc to the fusogenic H5WYG peptide.
Journal of mass spectrometry : JMS 2009;44(8):1163-70.
2009: Midoux Patrick; Pichon Chantal; Yaouanc Jean-Jacques; Jaffrès Paul-Alain
Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers.
British journal of pharmacology 2009;157(2):166-78.
2009: Gonçalves Cristine; Ardourel Marie-Yvonne; Decoville Martine; Breuzard Gilles; Midoux Patrick; Hartmann Brigitte; Pichon Chantal
An optimized extended DNA kappa B site that enhances plasmid DNA nuclear import and gene expression.
The journal of gene medicine 2009;11(5):401-11.
2009: Buré Corinne; Maget Régine; Delmas Agnès F; Pichon Chantal; Midoux Patrick
Histidine-rich peptide: evidence for a single zinc-binding site on H5WYG peptide that promotes membrane fusion at neutral pH.
Journal of mass spectrometry : JMS 2009;44(1):81-9.
2008: Midoux Patrick; Breuzard Gilles; Gomez Jean Pierre; Pichon Chantal
Polymer-based gene delivery: a current review on the uptake and intracellular trafficking of polyplexes.
Current gene therapy 2008;8(5):335-52.
2008: Mével Mathieu; Neveu Cécile; Gonçalves Cristine; Yaouanc Jean-Jacques; Pichon Chantal; Jaffrès Paul-Alain; Midoux Patrick
Novel neutral imidazole-lipophosphoramides for transfection assays.
Chemical communications (Cambridge, England) 2008;(27):3124-6.
2008: Breuzard Gilles; Tertil Magdalena; Gonçalves Cristine; Cheradame Hervé; Géguan Philippe; Pichon Chantal; Midoux Patrick
Nuclear delivery of NFkappaB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging.
Nucleic acids research 2008;36(12):e71.
2008: Mével Mathieu; Breuzard Gilles; Yaouanc Jean-Jacques; Clément Jean-Claude; Lehn Pierre; Pichon Chantal; Jaffrès Paul-Alain; Midoux Patrick
Synthesis and transfection activity of new cationic phosphoramidate lipids: high efficiency of an imidazolium derivative.
Chembiochem : a European journal of chemical biology 2008;9(9):1462-71.
2007: Mockey M; Bourseau E; Chandrashekhar V; Chaudhuri A; Lafosse S; Le Cam E; Quesniaux V F J; Ryffel B; Pichon C; Midoux P
mRNA-based cancer vaccine: prevention of B16 melanoma progression and metastasis by systemic injection of MART1 mRNA histidylated lipopolyplexes.
Cancer gene therapy 2007;14(9):802-14.
2006: Mennesson Eric; Erbacher Patrick; Kuzak Mateusz; Kieda Claudine; Midoux Patrick; Pichon Chantal
DNA/cationic polymer complex attachment on a human vascular endothelial cell monolayer exposed to a steady laminar flow.
Journal of controlled release : official journal of the Controlled Release Society 2006;114(3):389-97.
2006: Mockey Michael; Gonçalves Cristine; Dupuy Franck P; Lemoine François M; Pichon Chantal; Midoux Patrick
mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level.
Biochemical and biophysical research communications 2006;340(4):1062-8.
2005: Mennesson Eric; Erbacher Patrick; Piller Véronique; Kieda Claudine; Midoux Patrick; Pichon Chantal
Transfection efficiency and uptake process of polyplexes in human lung endothelial cells: a comparative study in non-polarized and polarized cells.
The journal of gene medicine 2005;7(6):729-38.
2004: Montier T; Delépine P; Pichon C; Férec C; Porteous D J; Midoux P
Non-viral vectors in cystic fibrosis gene therapy: progress and challenges.
Trends in biotechnology 2004;22(11):586-92.
2004: Elmadbouh Ibrahim; Rossignol Patrick; Meilhac Olivier; Vranckx Roger; Pichon Chantal; Pouzet Bruno; Midoux Patrick; Michel Jean-Baptiste
Optimization of in vitro vascular cell transfection with non-viral vectors for in vivo applications.
The journal of gene medicine 2004;6(10):1112-24.
2004: Gonçalves Christine; Mennesson Eric; Fuchs Renate; Gorvel Jean-Pierre; Midoux Patrick; Pichon Chantal
Macropinocytosis of polyplexes and recycling of plasmid via the clathrin-dependent pathway impair the transfection efficiency of human hepatocarcinoma cells.
Molecular therapy : the journal of the American Society of Gene Therapy 2004;10(2):373-85.
2004: Singh Rajkumar Sunil; Gonçalves Christine; Sandrin Pierre; Pichon Chantal; Midoux Patrick; Chaudhuri Arabinda
On the gene delivery efficacies of pH-sensitive cationic lipids via endosomal protonation: a chemical biology investigation.
Chemistry & biology 2004;11(5):713-23.
2003: Kumar V V; Pichon C; Refregiers M; Guerin B; Midoux P; Chaudhuri A
Single histidine residue in head-group region is sufficient to impart remarkable gene transfection properties to cationic lipids: evidence for histidine-mediated membrane fusion at acidic pH.
Gene therapy 2003;10(15):1206-15.
2002: Midoux Patrick; LeCam Eric; Coulaud Dominique; Delain Etienne; Pichon Chantal
Histidine containing peptides and polypeptides as nucleic acid vectors.
Somatic cell and molecular genetics 2002;27(1-6):27-47.
2002: Pichon Chantal; Guérin Brigitte; Réfrégiers Matthieu; Gonçalves Christine; Vigny Paul; Midoux Patrick
Zinc improves gene transfer mediated by DNA/cationic polymer complexes.
The journal of gene medicine 2002;4(5):548-59.
2002: Gonçalves Christine; Pichon Chantal; Guérin Brigitte; Midoux Patrick
Intracellular processing and stability of DNA complexed with histidylated polylysine conjugates.
The journal of gene medicine 2002;4(3):271-81.
2002: Pichon Chantal; LeCam Eric; Guérin Brigitte; Coulaud Dominique; Delain Etienne; Midoux Patrick
Poly[Lys-(AEDTP)]: a cationic polymer that allows dissociation of pDNA/cationic polymer complexes in a reductive medium and enhances polyfection.
Bioconjugate chemistry 2002;13(1):76-82.
2001: Pichon C; Gonçalves C; Midoux P
Histidine-rich peptides and polymers for nucleic acids delivery.
Advanced drug delivery reviews 2001;53(1):75-94.
2001: Bello Roufaï M; Midoux P
Histidylated polylysine as DNA vector: elevation of the imidazole protonation and reduced cellular uptake without change in the polyfection efficiency of serum stabilized negative polyplexes.
Bioconjugate chemistry 2001;12(1):92-9.
2000: Freulon I; Monsigny M; Midoux P; Mayer R
Spacer length dependence on the efficiency of dimeric anionic peptides in gene transfer by glycosylated polylysine/plasmid complexes.
Bioscience reports 2000;20(5):383-98.
2000: Fajac I; Allo J C; Souil E; Merten M; Pichon C; Figarella C; Monsigny M; Briand P; Midoux P
Histidylated polylysine as a synthetic vector for gene transfer into immortalized cystic fibrosis airway surface and airway gland serous cells.
The journal of gene medicine 2000;2(5):368-78.
2000: Allo J C; Midoux P; Merten M; Souil E; Lipecka J; Figarella C; Monsigny M; Briand P; Fajac I
Efficient gene transfer into human normal and cystic fibrosis tracheal gland serous cells with synthetic vectors.
American journal of respiratory cell and molecular biology 2000;22(2):166-75.
2000: Pichon C; Roufaï M B; Monsigny M; Midoux P
Histidylated oligolysines increase the transmembrane passage and the biological activity of antisense oligonucleotides.
Nucleic acids research 2000;28(2):504-12.
1999: Midoux P; Monsigny M
Efficient gene transfer by histidylated polylysine/pDNA complexes.
Bioconjugate chemistry 1999;10(3):406-11.
1999: Monsigny M; Midoux P; Mayer R; Roche A C
Glycotargeting: influence of the sugar moiety on both the uptake and the intracellular trafficking of nucleic acid carried by glycosylated polymers.
Bioscience reports 1999;19(2):125-32.
1999: Kichler A; Freulon I; Boutin V; Mayer R; Monsigny M; Midoux P
Glycofection in the presence of anionic fusogenic peptides: a study of the parameters affecting the peptide-mediated enhancement of the transfection efficiency.
The journal of gene medicine 1999;1(2):134-43.
1999: Fajac I; Briand P; Monsigny M; Midoux P
Sugar-mediated uptake of glycosylated polylysines and gene transfer into normal and cystic fibrosis airway epithelial cells.
Human gene therapy 1999;10(3):395-406.
1998: Bartholeyns J; Romet-Lemonne J L; Chokri M; Buyse M; Velu T; Bruyns C; Van de Winkel J J; Heeney J; Koopman G; Malmsten M; De Groote D; Monsigny M; Midoux P; Alarcon B
Cellular vaccines.
Research in immunology 1998;149(7-8):647-9.
1998: Quétard C; Bourgerie S; Normand-Sdiqui N; Mayer R; Strecker G; Midoux P; Roche A C; Monsigny M
Novel glycosynthons for glycoconjugate preparation: oligosaccharylpyroglutamylanilide derivatives.
Bioconjugate chemistry 1998;9(2):268-76.
1998: Midoux P; Kichler A; Boutin V; Maurizot J C; Monsigny M
Membrane permeabilization and efficient gene transfer by a peptide containing several histidines.
Bioconjugate chemistry 1998;9(2):260-7.
1998: Monsigny M; Quétard C; Bourgerie S; Delay D; Pichon C; Midoux P; Mayer R; Roche A C
Glycotargeting: the preparation of glyco-amino acids and derivatives from unprotected reducing sugars.
Biochimie 1998;80(2):99-108.
1997: Pichon C; Freulon I; Midoux P; Mayer R; Monsigny M; Roche A C
Cytosolic and nuclear delivery of oligonucleotides mediated by an amphiphilic anionic peptide.
Antisense & nucleic acid drug development 1997;7(4):335-43.
1997: Kollen W; Erbacher P; Midoux P; Roche A C; Monsigny M; Glick M C; Scanlin T F
Glycosylated polylysines. Nonviral vectors for gene transfer into cystic fibrosis airway epithelial cells.
Chest 1997;111(6 Suppl):95S-96S.
1997: Erbacher P; Roche A C; Monsigny M; Midoux P
The reduction of the positive charges of polylysine by partial gluconoylation increases the transfection efficiency of polylysine/DNA complexes.
Biochimica et biophysica acta 1997;1324(1):27-36.
1996: Stewart A J; Pichon C; Meunier L; Midoux P; Monsigny M; Roche A C
Enhanced biological activity of antisense oligonucleotides complexed with glycosylated poly-L-lysine.
Molecular pharmacology 1996;50(6):1487-94.
1996: Kollen W J; Midoux P; Erbacher P; Yip A; Roche A C; Monsigny M; Glick M C; Scanlin T F
Gluconoylated and glycosylated polylysines as vectors for gene transfer into cystic fibrosis airway epithelial cells.
Human gene therapy 1996;7(13):1577-86.
1996: Erbacher P; Roche A C; Monsigny M; Midoux P
Putative role of chloroquine in gene transfer into a human hepatoma cell line by DNA/lactosylated polylysine complexes.
Experimental cell research 1996;225(1):186-94.
1996: Erbacher P; Bousser M T; Raimond J; Monsigny M; Midoux P; Roche A C
Gene transfer by DNA/glycosylated polylysine complexes into human blood monocyte-derived macrophages.
Human gene therapy 1996;7(6):721-9.
1996: Avraméas A; McIlroy D; Hosmalin A; Autran B; Debré P; Monsigny M; Roche A C; Midoux P
Expression of a mannose/fucose membrane lectin on human dendritic cells.
European journal of immunology 1996;26(2):394-400.
1996: Monsigny M; Midoux P; Roche A C; Legrand A; Mayer R
[Selective transfection of animal cells by non viral vectors: polylysine carrying recognition signals]
Comptes rendus des séances de la Société de biologie et de ses filiales 1996;190(1):39-43.
1995: Midoux P; Mayer R; Monsigny M
Membrane permeabilization by alpha-helical peptides: a flow cytometry study.
Biochimica et biophysica acta 1995;1239(2):249-56.
1995: Erbacher P; Roche A C; Monsigny M; Midoux P
Glycosylated polylysine/DNA complexes: gene transfer efficiency in relation with the size and the sugar substitution level of glycosylated polylysines and with the plasmid size.
Bioconjugate chemistry 1995;6(4):401-10.
1993: Midoux P; Mendes C; Legrand A; Raimond J; Mayer R; Monsigny M; Roche A C
Specific gene transfer mediated by lactosylated poly-L-lysine into hepatoma cells.
Nucleic acids research 1993;21(4):871-8.
1993: Carpentier V; Midoux P; Monsigny M; Roche A C
Endocytosis of alpha 1-acid glycoprotein variants by human monocytic lineage cells.
Biology of the cell / under the auspices of the European Cell Biology Organization 1993;77(2):187-93.
1992: Bonfils E; Depierreux C; Midoux P; Thuong N T; Monsigny M; Roche A C
Drug targeting: synthesis and endocytosis of oligonucleotide-neoglycoprotein conjugates.
Nucleic acids research 1992;20(17):4621-9.
1992: Bonfils E; Mendes C; Roche A C; Monsigny M; Midoux P
Uptake by macrophages of a biotinylated oligo-alpha-deoxythymidylate by using mannosylated streptavidin.
Bioconjugate chemistry 1992;3(4):277-84.
1992: Midoux P; Martin A; Collet B; Monsigny M; Roche A C; Toujas L
Activation of mouse macrophages by muramyl dipeptide coupled with an anti-macrophage monoclonal antibody.
Bioconjugate chemistry 1992;3(2):194-9.
1991: Pimpaneau V; Midoux P; Monsigny M; Roche A C
Characterization and isolation of an intracellular D-mannose-specific receptor from human promyelocytic HL60 cells.
Carbohydrate research 1991;213():95-108.
1991: Breton P; Midoux P; Petit C; Bousser M T; Roche A C; Mayer R; Monsigny M
Production of macrophage-derived cytotoxic factor by N-[3-[(carbamoylmethyl)thio]propionylated] neoglycoproteins.
Bioconjugate chemistry 1991;2(1):16-8.
1990: Roche A C; Midoux P; Pimpaneau V; Nègre E; Mayer R; Monsigny M
Endocytosis mediated by monocyte and macrophage membrane lectins--application to antiviral drug targeting.
Research in virology 1990;141(2):243-9.
1990: Midoux P; Negre E; Roche A C; Mayer R; Monsigny M; Balzarini J; De Clercq E; Mayer E; Ghaffar A; Gangemi J D
Drug targeting: anti-HSV-1 activity of mannosylated polymer-bound 9-(2-phosphonylmethoxyethyl)adenine.
Biochemical and biophysical research communications 1990;167(3):1044-9.
1990: Monsigny M; Midoux P; Depierreux C; Bebear C; Le Bris M T; Valeur B
Benzoxazinone kanamycin A conjugate. A new fluorescent probe suitable to detect mycoplasmas in cell culture.
Biology of the cell / under the auspices of the European Cell Biology Organization 1990;70(3):101-5.
1989: Midoux P; Petit C; Pellen P; Toujas L; Monsigny M; Roche A C
Macrophage antigens associated with adhesion: identification by a monoclonal antibody specific for Lewis lung carcinoma cells.
Experimental cell research 1989;183(1):168-78.
1989: Monsigny M; Midoux P; Le Bris M T; Roche A C; Valeur B
Benzoxazinone derivatives: new fluorescent probes for two-color flow cytometry analysis using one excitation wavelength.
Biology of the cell / under the auspices of the European Cell Biology Organization 1989;67(2):193-200.
1989: Pimpaneau V; Midoux P; Durand G; De Baetselier P; Monsigny M; Roche A C
Endocytosis of alpha 1-acid glycoprotein variants and of neoglycoproteins containing mannose derivatives by a mouse hybridoma cell line (2C11-12). Comparison with mouse peritoneal macrophages.
Glycoconjugate journal 1989;6(4):561-74.
1989: Derrien D; Midoux P; Petit C; Nègre E; Mayer R; Monsigny M; Roche A C
Muramyl dipeptide bound to poly-L-lysine substituted with mannose and gluconoyl residues as macrophage activators.
Glycoconjugate journal 1989;6(2):241-55.
1988: Monsigny M; Roche A C; Kieda C; Midoux P; Obrénovitch A
Characterization and biological implications of membrane lectins in tumor, lymphoid and myeloid cells.
Biochimie 1988;70(11):1633-49.
1988: Monsigny M; Roche A C; Midoux P
Endogenous lectins and drug targeting.
Annals of the New York Academy of Sciences 1988;551():399-413; discussion 413-4.
1987: Midoux P; Roche A C; Monsigny M
Quantitation of the binding, uptake, and degradation of fluoresceinylated neoglycoproteins by flow cytometry.
Cytometry 1987;8(3):327-34.
1986: Sève A P; Hubert J; Bouvier D; Bourgeois C; Midoux P; Roche A C; Monsigny M
Analysis of sugar-binding sites in mammalian cell nuclei by quantitative flow microfluorometry.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(16):5997-6001.
1986: Midoux P; Roche A C; Monsigny M
Estimation of the degradation of endocytosed material by flow cytofluorometry using two neoglycoproteins containing different numbers of fluorescein molecules.
Biology of the cell / under the auspices of the European Cell Biology Organization 1986;58(3):221-5.
1985: Roche A C; Midoux P; Bouchard P; Monsigny M
Membrane lectins on human monocytes. Maturation-dependent modulation of 6-phosphomannose and mannose receptors.
FEBS letters 1985;193(1):63-8.
1984: Roche A C; Bailly P; Midoux P; Monsigny M
Selective macrophage activation by muramyldipeptide bound to monoclonal antibodies specific for mouse tumor cells.
Cancer immunology, immunotherapy : CII 1984;18(3):155-9.
1984: Midoux P; Maillet T; Thérain F; Monsigny M; Roche A C
Tumor localization of Lewis lung carcinoma with radiolabeled monoclonal antibodies.
Cancer immunology, immunotherapy : CII 1984;18(1):19-23.
1984: Midoux P; Roche A C; Monsigny M
Monoclonal antibodies (IgM) against a murine carcinoma, Lewis lung carcinoma (3LL): production, purification and in vitro selectivity.
Immunology letters 1984;8(3):131-6.
1984: Monsigny M; Roche A C; Midoux P
Uptake of neoglycoproteins via membrane lectin(s) of L1210 cells evidenced by quantitative flow cytofluorometry and drug targeting.
Biology of the cell / under the auspices of the European Cell Biology Organization 1984;51(2):187-96.
1983: Roche A C; Barzilay M; Midoux P; Junqua S; Sharon N; Monsigny M
Sugar-specific endocytosis of glycoproteins by Lewis lung carcinoma cells.
Journal of cellular biochemistry 1983;22(3):131-40.

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