Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Frank Miedema

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

HIV-1

Disorders

Anatomy

Physiology

Procedures

CD4 Lymphocyte Count

Concepts & Ideas

Phenomena

HIV Seropositivity

Chemicals & Drugs

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
40
Coutinho, Roel
38
Van Baarle, Debbie
37
Roos, Marijke Th
37
Schuitemaker, Hanneke
35
Otto, Sigrid
34
Lange, Joep
25
Klein, Michel
24
Schellekens, P T A
23
van Lier, René
23
Koot, M
23
de Wolf, Frank
21
Hamann, Dörte
20
Goudsmit, Jaap
18
Keet, IP
17
Hazenberg, Mette

Sign-in to see all Coauthors

Publications

TOP 3
Miedema Frank
A brief history of HIV vaccine research: stepping back to the drawing board?
Steingrover Radjin; Pogány Katalyn; Fernandez Garcia Evian; Jurriaans Suzanne; Brinkman Kees; Schuitemaker Hanneke; Miedema Frank; Lange Joep Ma; Prins Jan M
HIV-1 viral rebound dynamics after a single treatment interruption depends on time of initiation of highly active antiretroviral therapy.
Vrisekoop Nienke; van Gent Rogier; de Boer Anne Bregje; Otto Sigrid A; Borleffs Jan C C; Steingrover Radjin; Prins Jan M; Kuijpers Taco W; Wolfs Tom F W; Geelen Sibyl P M; Vulto Irma; Lansdorp Peter; Tesselaar Kiki; Borghans José A M; Miedema Frank
Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Frank Miedema (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2008: Miedema Frank
A brief history of HIV vaccine research: stepping back to the drawing board?
AIDS (London, England) 2008;22(14):1699-703.
2008: Steingrover Radjin; Pogány Katalyn; Fernandez Garcia Evian; Jurriaans Suzanne; Brinkman Kees; Schuitemaker Hanneke; Miedema Frank; Lange Joep Ma; Prins Jan M
HIV-1 viral rebound dynamics after a single treatment interruption depends on time of initiation of highly active antiretroviral therapy.
AIDS (London, England) 2008;22(13):1583-8.
2008: Vrisekoop Nienke; van Gent Rogier; de Boer Anne Bregje; Otto Sigrid A; Borleffs Jan C C; Steingrover Radjin; Prins Jan M; Kuijpers Taco W; Wolfs Tom F W; Geelen Sibyl P M; Vulto Irma; Lansdorp Peter; Tesselaar Kiki; Borghans José A M; Miedema Frank
Restoration of the CD4 T cell compartment after long-term highly active antiretroviral therapy without phenotypical signs of accelerated immunological aging.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(2):1573-81.
2008: Vrisekoop Nienke; den Braber Ineke; de Boer Anne Bregje; Ruiter An F C; Ackermans Mariëtte T; van der Crabben Saskia N; Schrijver Elise H R; Spierenburg Gerrit; Sauerwein Hans P; Hazenberg Mette D; de Boer Rob J; Miedema Frank; Borghans José A M; Tesselaar Kiki
Sparse production but preferential incorporation of recently produced naive T cells in the human peripheral pool.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(16):6115-20.
2008: Tesselaar Kiki; Miedema Frank
Growth hormone resurrects adult human thymus during HIV-1 infection.
The Journal of clinical investigation 2008;118(3):844-7.
2008: Navis Marjon; Schellens Ingrid M M; van Swieten Peter; Borghans José A M; Miedema Frank; Kootstra Neeltje A; van Baarle Debbie; Schuitemaker Hanneke
A nonprogressive clinical course in HIV-infected individuals expressing human leukocyte antigen B57/5801 is associated with preserved CD8+ T lymphocyte responsiveness to the HW9 epitope in Nef.
The Journal of infectious diseases 2008;197(6):871-9.
2008: Schellens Ingrid M M; Kesmir Can; Miedema Frank; van Baarle Debbie; Borghans José A M
An unanticipated lack of consensus cytotoxic T lymphocyte epitopes in HIV-1 databases: the contribution of prediction programs.
AIDS (London, England) 2008;22(1):33-7.
2008: Schellens Ingrid M M; Borghans José A M; Jansen Christine A; De Cuyper Iris M; Geskus Ronald B; van Baarle Debbie; Miedema Frank
Abundance of early functional HIV-specific CD8+ T cells does not predict AIDS-free survival time.
PloS one 2008;3(7):e2745.
2007: Vermeulen Joost N; Prins Jan M; Bunnik Evelien; Hack C Erik; Jurriaans Suzanne; Miedema Frank; Lange Joep M A; Schuitemaker Hanneke
Intravenous immunoglobulin (IVIG) treatment for modulation of immune activation in human immunodeficiency virus type 1 infected therapy-naive individuals.
AIDS research and human retroviruses 2007;23(11):1348-53.
2007: Navis Marjon; Schellens Ingrid; van Baarle Debbie; Borghans José; van Swieten Peter; Miedema Frank; Kootstra Neeltje; Schuitemaker Hanneke
Viral replication capacity as a correlate of HLA B57/B5801-associated nonprogressive HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3133-43.
2007: Casula Miriam; Vrisekoop Nienke; Wit Ferdinand W; de Baar Michel P; de Ronde Anthony; Miedema Frank; Reiss Peter
Mitochondrial DNA decline in T cells of HIV-1 seroconverters may be dependent on immune activation.
The Journal of infectious diseases 2007;196(3):371-6.
2007: Bronke Corine; Jansen Christine A; Westerlaken Geertje H A; De Cuyper Iris M; Miedema Frank; Tesselaar Kiki; van Baarle Debbie
Shift of CMV-specific CD4+ T-cells to the highly differentiated CD45RO-CD27- phenotype parallels loss of proliferative capacity and precedes progression to HIV-related CMV end-organ disease.
Clinical immunology (Orlando, Fla.) 2007;124(2):190-9.
2007: Choudhary Shailesh K; Vrisekoop Nienke; Jansen Christine A; Otto Sigrid A; Schuitemaker Hanneke; Miedema Frank; Camerini David
Low immune activation despite high levels of pathogenic human immunodeficiency virus type 1 results in long-term asymptomatic disease.
Journal of virology 2007;81(16):8838-42.
2007: Tsegaye Aster; Ran Leonie; Wolday Dawit; Petros Beyene; Dorigo Wendelien; Piriou Erwan; Messele Tsehaynesh; Sanders Eduard; Tilahun Tesfaye; Eshetu Deresse; Schuitemaker Hanneke; Coutinho Roel A; Miedema Frank; Borghans José; van Baarle Debbie
HIV-1 Subtype C gag-specific T-cell responses in relation to human leukocyte antigens in a diverse population of HIV-infected Ethiopians.
Journal of acquired immune deficiency syndromes (1999) 2007;45(4):389-400.
2007: Tsegaye Aster; Ran Leonie; Wolday Dawit; Petros Beyene; Nanlohy Nening M; Meles Hailu; Girma Mulu; Hailu Ermias; Borghans José; Miedema Frank; van Baarle Debbie
Stable pattern of HIV-1 subtype C Gag-specific T-cell responses coincides with slow rate of CD4 T-cell decline in HIV-infected Ethiopians.
AIDS (London, England) 2007;21(3):369-72.
2006: Tegbaru Belete; Wolday Dawit; Messele Tsehaynesh; Legesse Mengistu; Mekonnen Yared; Miedema Frank; van Baarle Debbie
Tuberculin skin test conversion and reactivity rates among adults with and without human immunodeficiency virus in urban settings in Ethiopia.
Clinical and vaccine immunology : CVI 2006;13(7):784-9.
2006: Borghans José A; Bredius Robbert G; Hazenberg Mette D; Roelofs Helene; Jol-van der Zijde Els C; Heidt Jeroen; Otto Sigrid A; Kuijpers Taco W; Fibbe Willem E; Vossen Jaak M; Miedema Frank; van Tol Maarten J
Early determinants of long-term T-cell reconstitution after hematopoietic stem cell transplantation for severe combined immunodeficiency.
Blood 2006;108(2):763-9.
2006: Jansen Christine A; van Baarle Debbie; Miedema Frank
HIV-specific CD4+ T cells and viremia: who's in control?
Trends in immunology 2006;27(3):119-24.
2006: Geels Mark J; Jansen Christine A; Baan Elly; De Cuyper Iris M; van Schijndel Gijs J M; Schuitemaker Hanneke; Goudsmit Jaap; Pollakis Georgios; Miedema Frank; Paxton William A; van Baarle Debbie
CTL escape and increased viremia irrespective of HIV-specific CD4+ T-helper responses in two HIV-infected individuals.
Virology 2006;345(1):209-19.
2006: Jansen Christine A; De Cuyper Iris M; Hooibrink Berend; van der Bij Akke K; van Baarle Debbie; Miedema Frank
Prognostic value of HIV-1 Gag-specific CD4+ T-cell responses for progression to AIDS analyzed in a prospective cohort study.
Blood 2006;107(4):1427-33.
2006: Miedema Frank
T cell dynamics and protective immunity in HIV infection: a brief history of ideas.
Current opinion in HIV and AIDS 2006;1(1):1-2.
2006: Jansen Christine A; Piriou Erwan; De Cuyper Iris M; van Dort Karel; Lange Joep M A; Miedema Frank; van Baarle Debbie
Long-term highly active antiretroviral therapy in chronic HIV-1 infection: evidence for reconstitution of antiviral immunity.
Antiviral therapy 2006;11(1):105-16.
2005: Vrisekoop Nienke; Sankatsing Sanjay U C; Jansen Christine A; Roos Marijke Th L; Otto Sigrid A; Schuitemaker Hanneke; Lange Joep M A; Prins Jan M; Miedema Frank
Short communication: No detrimental immunological effects of mycophenolate mofetil and HAART in treatment-naive acute and chronic HIV-1-infected patients.
AIDS research and human retroviruses 2005;21(12):991-6.
2005: Koning Fransje A; Otto Sigrid A; Hazenberg Mette D; Dekker Linda; Prins Maria; Miedema Frank; Schuitemaker Hanneke
Low-level CD4+ T cell activation is associated with low susceptibility to HIV-1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):6117-22.
2005: Hailu Asrat; van Baarle Debbie; Knol Gerlinde J; Berhe Nega; Miedema Frank; Kager Piet A
T cell subset and cytokine profiles in human visceral leishmaniasis during active and asymptomatic or sub-clinical infection with Leishmania donovani.
Clinical immunology (Orlando, Fla.) 2005;117(2):182-91.
2005: Piriou Erwan; van Dort Karel; Nanlohy Nening M; van Oers Marinus H J; Miedema Frank; van Baarle Debbie
Loss of EBNA1-specific memory CD4+ and CD8+ T cells in HIV-infected patients progressing to AIDS-related non-Hodgkin lymphoma.
Blood 2005;106(9):3166-74.
2005: Mekonnen Yared; Geskus Ronald B; Hendriks Jan C M; Messele Tsehaynesh; Borghans Jose; Miedema Frank; Wolday Dawit; Coutinho Roel A; Dukers Nicole H T M
Low CD4 T cell counts before HIV-1 seroconversion do not affect disease progression in Ethiopian factory workers.
The Journal of infectious diseases 2005;192(5):739-48.
2005: Piriou Erwan; Jansen Christine A; van Dort Karel; De Cuyper Iris; Nanlohy Nening M; Lange Joep M A; van Oers Marinus H J; Miedema Frank; van Baarle Debbie
Reconstitution of EBV latent but not lytic antigen-specific CD4+ and CD8+ T cells after HIV treatment with highly active antiretroviral therapy.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(3):2010-7.
2005: Kloosterboer Nico; Groeneveld Paul H P; Jansen Christine A; van der Vorst Teun J K; Koning Fransje; Winkel Carel N; Duits Ashley J; Miedema Frank; van Baarle Debbie; van Rij Ronald P; Brinkman Kees; Schuitemaker Hanneke
Natural controlled HIV infection: preserved HIV-specific immunity despite undetectable replication competent virus.
Virology 2005;339(1):70-80.
2005: Jansen Christine A; De Cuyper Iris M; Steingrover Radjin; Jurriaans Suzanne; Sankatsing Sanjay U C; Prins Jan M; Lange Joep M A; van Baarle Debbie; Miedema Frank
Analysis of the effect of highly active antiretroviral therapy during acute HIV-1 infection on HIV-specific CD4 T cell functions.
AIDS (London, England) 2005;19(11):1145-54.
2005: Wolday Dawit; Tegbaru Belete; Kassu Afework; Messele Tsehaynesh; Coutinho Roel; van Baarle Debbie; Miedema Frank
Expression of chemokine receptors CCR5 and CXCR4 on CD4+ T cells and plasma chemokine levels during treatment of active tuberculosis in HIV-1-coinfected patients.
Journal of acquired immune deficiency syndromes (1999) 2005;39(3):265-71.
2005: Bronke C; Westerlaken G H A; Miedema F; Tesselaar K; van Baarle D
Progression to CMV end-organ disease in HIV-1-infected individuals despite abundance of highly differentiated CMV-specific CD8+ T-cells.
Immunology letters 2005;97(2):215-24.
2005: Piriou Erwan R; van Dort Karel; Nanlohy Nening M; van Oers Marinus H; Miedema Frank; van Baarle Debbie
Novel method for detection of virus-specific CD41+ T cells indicates a decreased EBV-specific CD4+ T cell response in untreated HIV-infected subjects.
European journal of immunology 2005;35(3):796-805.
2005: Bronke Corine; Palmer Nanette M; Jansen Christine A; Westerlaken Geertje H A; Polstra Abeltje M; Reiss Peter; Bakker Margreet; Miedema Frank; Tesselaar Kiki; van Baarle Debbie
Dynamics of cytomegalovirus (CMV)-specific T cells in HIV-1-infected individuals progressing to AIDS with CMV end-organ disease.
The Journal of infectious diseases 2005;191(6):873-80.
2005: van Baarle Debbie; Tsegaye Aster; Miedema Frank; Akbar Arne
Significance of senescence for virus-specific memory T cell responses: rapid ageing during chronic stimulation of the immune system.
Immunology letters 2005;97(1):19-29.
2005: Borghans José A M; Hazenberg Mette D; Miedema Frank
Limited role for the thymus in SIV pathogenesis.
European journal of immunology 2005;35(1):42-5.
2005: Jansen Christine A; Kostense Stefan; Vandenberghe Kristin; Nanlohy Nening M; De Cuyper Iris M; Piriou Erwan; Manting Erik H; Miedema Frank; van Baarle Debbie
High responsiveness of HLA-B57-restricted Gag-specific CD8+ T cells in vitro may contribute to the protective effect of HLA-B57 in HIV-infection.
European journal of immunology 2005;35(1):150-8.
2004: Jansen Christine A; Piriou Erwan; Bronke Corine; Vingerhoed José; Kostense Stefan; van Baarle Debbie; Miedema Frank
Characterization of virus-specific CD8(+) effector T cells in the course of HIV-1 infection: longitudinal analyses in slow and rapid progressors.
Clinical immunology (Orlando, Fla.) 2004;113(3):299-309.
2004: Hazenberg Mette D; Otto Sigrid A; van Rossum Annemarie M C; Scherpbier Henriëtte J; de Groot Ronald; Kuijpers Taco W; Lange Joep M A; Hamann Dörte; de Boer Rob J; Borghans José A M; Miedema Frank
Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1.
Blood 2004;104(12):3513-9.
2004: Sankatsing Sanjay U C; Jurriaans Suzanne; van Swieten Peter; van Leth Frank; Cornelissen Marion; Miedema Frank; Lange Joep M A; Schuitemaker Hanneke; Prins Jan M
Highly active antiretroviral therapy with or without mycophenolate mofetil in treatment-naive HIV-1 patients.
AIDS (London, England) 2004;18(14):1925-31.
2004: van Asten Liselotte; Danisman Figen; Otto Sigrid A; Borghans José A M; Hazenberg Mette D; Coutinho Roel A; Prins Maria; Miedema Frank
Pre-seroconversion immune status predicts the rate of CD4 T cell decline following HIV infection.
AIDS (London, England) 2004;18(14):1885-93.
2004: Piriou Erwan R; van Dort Karel; Nanlohy Nening M; Miedema Frank; van Oers Marinus H; van Baarle Debbie
Altered EBV viral load setpoint after HIV seroconversion is in accordance with lack of predictive value of EBV load for the occurrence of AIDS-related non-Hodgkin lymphoma.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6931-7.
2003: Tsegaye Aster; Wolday Dawit; Otto Sigrid; Petros Beyene; Assefa Tsehai; Alebachew Tsegaye; Hailu Ermias; Adugna Fekadu; Measho Worku; Dorigo Wendelien; Fontanet Arnaud L; van Baarle Debbie; Miedema Frank
Immunophenotyping of blood lymphocytes at birth, during childhood, and during adulthood in HIV-1-uninfected Ethiopians.
Clinical immunology (Orlando, Fla.) 2003;109(3):338-46.
2003: Hazenberg Mette D; Otto Sigrid A; van Benthem Birgit H B; Roos Marijke Th L; Coutinho Roel A; Lange Joep M A; Hamann Dörte; Prins Maria; Miedema Frank
Persistent immune activation in HIV-1 infection is associated with progression to AIDS.
AIDS (London, England) 2003;17(13):1881-8.
2003: Hazenberg Mette D; Otto Sigrid A; Hamann Dörte; Roos Marijke Th L; Schuitemaker Hanneke; de Boer Rob J; Miedema Frank
Depletion of naive CD4 T cells by CXCR4-using HIV-1 variants occurs mainly through increased T-cell death and activation.
AIDS (London, England) 2003;17(10):1419-24.
2003: Meij Pauline; van Esser Joost W J; Niesters Hubert G M; van Baarle Debbie; Miedema Frank; Blake Neil; Rickinson Alan B; Leiner Ingrid; Pamer Eric; Lowenberg Bob; Cornelissen Jan J; Gratama Jan W
Impaired recovery of Epstein-Barr virus (EBV)--specific CD8+ T lymphocytes after partially T-depleted allogeneic stem cell transplantation may identify patients at very high risk for progressive EBV reactivation and lymphoproliferative disease.
Blood 2003;101(11):4290-7.
2003: van Rij Ronald P; Hazenberg Mette D; van Benthem Birgit H B; Otto Sigrid A; Prins Maria; Miedema Frank; Schuitemaker Hanneke
Early viral load and CD4+ T cell count, but not percentage of CCR5+ or CXCR4+ CD4+ T cells, are associated with R5-to-X4 HIV type 1 virus evolution.
AIDS research and human retroviruses 2003;19(5):389-98.
2003: Bogaards Johannes A; Weverling Gerrit Jan; Geskus Ronald B; Miedema Frank; Lange Joep M A; Bossuyt Patrick M M; Goudsmit Jaap
Low versus high CD4 cell count as starting point for introduction of antiretroviral treatment in resource-poor settings: a scenario-based analysis.
Antiviral therapy 2003;8(1):43-50.
2003: Hazenberg Mette D; Borghans José A M; de Boer Rob J; Miedema Frank
Thymic output: a bad TREC record.
Nature immunology 2003;4(2):97-9.
2002: van Baarle Debbie; Kostense Stefan; van Oers Marinus H J; Hamann Dorte; Miedema Frank
Failing immune control as a result of impaired CD8+ T-cell maturation: CD27 might provide a clue.
Trends in immunology 2002;23(12):586-91.
2002: Cohen Stuart James; Hamann Dörte; Borleffs Jan; Roos Marijke; Miedema Frank; Boucher Charles; de Boer Rob
Reconstitution of naive T cells during antiretroviral treatment of HIV-infected adults is dependent on age.
AIDS (London, England) 2002;16(17):2263-6.
2002: Migueles Stephen A; Laborico Alisha C; Shupert W Lesley; Sabbaghian M Shirin; Rabin Ronald; Hallahan Claire W; Van Baarle Debbie; Kostense Stefan; Miedema Frank; McLaughlin Mary; Ehler Linda; Metcalf Julia; Liu Shuying; Connors Mark
HIV-specific CD8+ T cell proliferation is coupled to perforin expression and is maintained in nonprogressors.
Nature immunology 2002;3(11):1061-8.
2002: van Baarle Debbie; Kostense Stefan; Hovenkamp Egbert; Ogg Graham; Nanlohy Nening; Callan Margaret F C; Dukers Nicole H T M; McMichael Andrew J; van Oers Marinus H J; Miedema Frank
Lack of Epstein-Barr virus- and HIV-specific CD27- CD8+ T cells is associated with progression to viral disease in HIV-infection.
AIDS (London, England) 2002;16(15):2001-11.
2002: Rinke de Wit Tobias F; Tsegaye Aster; Wolday Dawit; Hailu Binyam; Aklilu Mathias; Sanders Eduard; Hagos Measho; Kliphuis Aletta; Pollakis Georgios; Krol Anneke; Geskus Ronald; Miedema Frank; Goudsmit Jaap; Coutinho Roel; Fontanet Arnaud L
Primary HIV-1 subtype C infection in Ethiopia.
Journal of acquired immune deficiency syndromes (1999) 2002;30(5):463-70.
2002: Van Baarle Debbie; Wolthers Katja C; Hovenkamp Egbert; Niesters Hubert G M; Osterhaus Albert D M E; Miedema Frank; Van Oers Marinus H J
Absolute level of Epstein-Barr virus DNA in human immunodeficiency virus type 1 infection is not predictive of AIDS-related non-Hodgkin lymphoma.
The Journal of infectious diseases 2002;186(3):405-9.
2002: Maas Jaap; Termorshuizen Fabian; Geskus Ronald B; Goettsch Wim; Coutinho Roel A; Miedema Frank; Van Loveren Henk
Amsterdam Cohort Study on HIV and AIDS: impact of exposure to UVR as estimated by means of a 2-year retrospective questionnaire on immune parameters in HIV positive males.
International journal of hygiene and environmental health 2002;205(5):373-7.
2002: Hazenberg Mette D; Otto Sigrid A; Wit Ferdinand W N M; Lange Joep M A; Hamann Dörte; Miedema Frank
Discordant responses during antiretroviral therapy: role of immune activation and T cell redistribution rather than true CD4 T cell loss.
AIDS (London, England) 2002;16(9):1287-9.
2002: Lindenburg Catharina E A; Stolte Ineke; Langendam Miranda W; Miedema Frank; Williams Ian G; Colebunders Robert; Weber Jonathan N; Fisher Martin; Coutinho Roel A
Long-term follow-up: no effect of therapeutic vaccination with HIV-1 p17/p24:Ty virus-like particles on HIV-1 disease progression.
Vaccine 2002;20(17-18):2343-7.
2002: Hazenberg Mette D; Otto Sigrid A; de Pauw Elmar S; Roelofs Helene; Fibbe Willem E; Hamann Dörte; Miedema Frank
T-cell receptor excision circle and T-cell dynamics after allogeneic stem cell transplantation are related to clinical events.
Blood 2002;99(9):3449-53.
2002: Kostense Stefan; Otto Sigrid A; Knol Gerlinde J; Manting Erik H; Nanlohy Nening M; Jansen Christine; Lange Joep M A; van Oers Marinus H J; Miedema Frank; van Baarle Debbie
Functional restoration of human immunodeficiency virus and Epstein-Barr virus-specific CD8(+) T cells during highly active antiretroviral therapy is associated with an increase in CD4(+) T cells.
European journal of immunology 2002;32(4):1080-9.
2002: Kostense Stefan; Vandenberghe Kristin; Joling Jeanine; Van Baarle Debbie; Nanlohy Nening; Manting Erik; Miedema Frank
Persistent numbers of tetramer+ CD8(+) T cells, but loss of interferon-gamma+ HIV-specific T cells during progression to AIDS.
Blood 2002;99(7):2505-11.
2002: de Pauw Elmar S D; Otto Sigrid A; Wijnen Juul T; Vossen Jaak M; van Weel Margreet H; Tanke Hans J; Miedema Frank; Willemze Roel; Roelofs Helene; Fibbe Willem E
Long-term follow-up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem cell exhaustion.
British journal of haematology 2002;116(2):491-6.
2002: van der Vliet Hans J J; von Blomberg B Mary E; Hazenberg Mette D; Nishi Nobusuke; Otto Sigrid A; van Benthem Birgit H; Prins Maria; Claessen Frans A; van den Eertwegh Alfons J M; Giaccone Giuseppe; Miedema Frank; Scheper Rik J; Pinedo Herbert M
Selective decrease in circulating V alpha 24+V beta 11+ NKT cells during HIV type 1 infection.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(3):1490-5.
2001: Hazenberg M D; Verschuren M C; Hamann D; Miedema F; van Dongen J J
T cell receptor excision circles as markers for recent thymic emigrants: basic aspects, technical approach, and guidelines for interpretation.
Journal of molecular medicine (Berlin, Germany) 2001;79(11):631-40.
2001: Goudsmit J; Weverling G J; van der Hoek L; de Ronde A; Miedema F; Coutinho R A; Lange J M; Boerlijst M C
Carrier rate of zidovudine-resistant HIV-1: the impact of failing therapy on transmission of resistant strains.
AIDS (London, England) 2001;15(17):2293-301.
2001: van Rossum A M; Scherpbier H J; van Lochem E G; Pakker N G; Slieker W A; Wolthers K C; Roos M T; Kuijpers J H; Hooijkaas H; Hartwig N G; Geelen S P; Wolfs T F; Lange J M; Miedema F; de Groot R;
Therapeutic immune reconstitution in HIV-1-infected children is independent of their age and pretreatment immune status.
AIDS (London, England) 2001;15(17):2267-75.
2001: Lindenburg C E; Langendam M W; Benthem B H; Miedema F; Coutinho R A
No evidence that vaccination with a polysaccharide pneumococcal vaccine protects drug users against all-cause pneumonia.
AIDS (London, England) 2001;15(10):1315-7.
2001: van Baarle D; Hovenkamp E; Callan M F; Wolthers K C; Kostense S; Tan L C; Niesters H G; Osterhaus A D; McMichael A J; van Oers M H; Miedema F
Dysfunctional Epstein-Barr virus (EBV)-specific CD8(+) T lymphocytes and increased EBV load in HIV-1 infected individuals progressing to AIDS-related non-Hodgkin lymphoma.
Blood 2001;98(1):146-55.
2001: Kostense S; Raaphorst F M; Joling J; Notermans D W; Prins J M; Danner S A; Reiss P; Lange J M; Teale J M; Miedema F
T cell expansions in lymph nodes and peripheral blood in HIV-1-infected individuals: effect of antiretroviral therapy.
AIDS (London, England) 2001;15(9):1097-107.
2001: Foudraine N A; Jurriaans S; Weverling G J; Burger D M; Hoetelmans R M; Roos M T; Maas J; Miedema F; Reiss P; Portegies P; de Wolf F; Lange J M
Durable HIV-1 suppression with indinavir after failing lamivudine-containing double nucleoside therapy: a randomized controlled trial.
Antiviral therapy 2001;6(1):55-62.
2001: Kostense S; Ogg G S; Manting E H; Gillespie G; Joling J; Vandenberghe K; Veenhof E Z; van Baarle D; Jurriaans S; Klein M R; Miedema F
High viral burden in the presence of major HIV-specific CD8(+) T cell expansions: evidence for impaired CTL effector function.
European journal of immunology 2001;31(3):677-86.
2001: Messele T; Brouwer M; Girma M; Fontanet A L; Miedema F; Hamann D; Rinke de Wit T F
Plasma levels of viro-immunological markers in HIV-infected and non-infected Ethiopians: correlation with cell surface activation markers.
Clinical immunology (Orlando, Fla.) 2001;98(2):212-9.
2000: Cohen Stuart J W; Hazebergh M D; Hamann D; Otto S A; Borleffs J C; Miedema F; Boucher C A; de Boer R J
The dominant source of CD4+ and CD8+ T-cell activation in HIV infection is antigenic stimulation.
Journal of acquired immune deficiency syndromes (1999) 2000;25(3):203-11.
2000: Hazenberg M D; Hamann D; Schuitemaker H; Miedema F
T cell depletion in HIV-1 infection: how CD4+ T cells go out of stock.
Nature immunology 2000;1(4):285-9.
2000: Hazenberg M D; Otto S A; Cohen Stuart J W; Verschuren M C; Borleffs J C; Boucher C A; Coutinho R A; Lange J M; Rinke de Wit T F; Tsegaye A; van Dongen J J; Hamann D; de Boer R J; Miedema F
Increased cell division but not thymic dysfunction rapidly affects the T-cell receptor excision circle content of the naive T cell population in HIV-1 infection.
Nature medicine 2000;6(9):1036-42.
2000: Roos M T; van Lier R A; Hamann D; Knol G J; Verhoofstad I; van Baarle D; Miedema F; Schellekens P T
Changes in the composition of circulating CD8+ T cell subsets during acute epstein-barr and human immunodeficiency virus infections in humans.
The Journal of infectious diseases 2000;182(2):451-8.
2000: Clark D R; Repping S; Pakker N G; Prins J M; Notermans D W; Wit F W; Reiss P; Danner S A; Coutinho R A; Lange J M; Miedema F
T-cell progenitor function during progressive human immunodeficiency virus-1 infection and after antiretroviral therapy.
Blood 2000;96(1):242-9.
2000: Messele T; Roos M T; Hamann D; Koot M; Fontanet A L; Miedema F; Schellekens P T; Rinke de Wit T F
Nonradioactive techniques for measurement of in vitro T-cell proliferation: alternatives to the [(3)H]thymidine incorporation assay.
Clinical and diagnostic laboratory immunology 2000;7(4):687-92.
2000: van Baarle D; Hovenkamp E; Dukers N H; Renwick N; Kersten M J; Goudsmit J; Coutinho R A; Miedema F; van Oers M H
High prevalence of Epstein-Barr virus type 2 among homosexual men is caused by sexual transmission.
The Journal of infectious diseases 2000;181(6):2045-9.
2000: Fleury S; Rizzardi G P; Chapuis A; Tambussi G; Knabenhans C; Simeoni E; Meuwly J Y; Corpataux J M; Lazzarin A; Miedema F; Pantaleo G
Long-term kinetics of T cell production in HIV-infected subjects treated with highly active antiretroviral therapy.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5393-8.
2000: Lindenburg K; Langendam M W; Veenstra J; Miedema F; Coutinho R
Long-term effects of therapeutic vaccination with rgp 120.
AIDS (London, England) 2000;14(2):203-4.
2000: Hazenberg M D; Stuart J W; Otto S A; Borleffs J C; Boucher C A; de Boer R J; Miedema F; Hamann D
T-cell division in human immunodeficiency virus (HIV)-1 infection is mainly due to immune activation: a longitudinal analysis in patients before and during highly active antiretroviral therapy (HAART).
Blood 2000;95(1):249-55.
1999: Nielsen S D; Clark D R; Hutchings M; Dam-Larsen S; Repping S; Nielsen J O; Mathiesen L; Miedema F; Hansen J E
Treatment with granulocyte colony-stimulating factor decreases the capacity of hematopoietic progenitor cells for generation of lymphocytes in human immunodeficiency virus-infected persons.
The Journal of infectious diseases 1999;180(6):1819-26.
1999: Ogg G S; Kostense S; Klein M R; Jurriaans S; Hamann D; McMichael A J; Miedema F
Longitudinal phenotypic analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocytes: correlation with disease progression.
Journal of virology 1999;73(11):9153-60.
1999: Notermans D W; Pakker N G; Hamann D; Foudraine N A; Kauffmann R H; Meenhorst P L; Goudsmit J; Roos M T; Schellekens P T; Miedema F; Danner S A
Immune reconstitution after 2 years of successful potent antiretroviral therapy in previously untreated human immunodeficiency virus type 1-infected adults.
The Journal of infectious diseases 1999;180(4):1050-6.
1999: Wolthers K C; Noest A J; Otto S A; Miedema F; De Boer R J
Normal telomere lengths in naive and memory CD4+ T cells in HIV type 1 infection: a mathematical interpretation.
AIDS research and human retroviruses 1999;15(12):1053-62.
1999: Keet I P; Tang J; Klein M R; LeBlanc S; Enger C; Rivers C; Apple R J; Mann D; Goedert J J; Miedema F; Kaslow R A
Consistent associations of HLA class I and II and transporter gene products with progression of human immunodeficiency virus type 1 infection in homosexual men.
The Journal of infectious diseases 1999;180(2):299-309.
1999: Pontesilli O; Carotenuto P; Kerkhof-Garde S R; Roos M T; Keet I P; Coutinho R A; Goudsmit J; Miedema F
Lymphoproliferative response to HIV type 1 p24 in long-term survivors of HIV type 1 infection is predictive of persistent AIDS-free infection.
AIDS research and human retroviruses 1999;15(11):973-81.
1999: Hamann D; Kostense S; Wolthers K C; Otto S A; Baars P A; Miedema F; van Lier R A
Evidence that human CD8+CD45RA+CD27- cells are induced by antigen and evolve through extensive rounds of division.
International immunology 1999;11(7):1027-33.
1999: Pontesilli O; Kerkhof-Garde S; Notermans D W; Foudraine N A; Roos M T; Klein M R; Danner S A; Lange J M; Miedema F
Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy.
The Journal of infectious diseases 1999;180(1):76-86.
1999: van Baarle D; Hovenkamp E; Kersten M J; Klein M R; Miedema F; van Oers M H
Direct Epstein-Barr virus (EBV) typing on peripheral blood mononuclear cells: no association between EBV type 2 infection or superinfection and the development of acquired immunodeficiency syndrome-related non-Hodgkin's lymphoma.
Blood 1999;93(11):3949-55.
1999: Pontesilli O; Kerkhof-Garde S; Pakker N G; Notermans D W; Roos M T; Klein M R; Danner S A; Miedema F
Antigen-specific T-lymphocyte proliferative responses during highly active antiretroviral therapy (HAART) of HIV-1 infection.
Immunology letters 1999;66(1-3):213-7.
1999: Messele T; Abdulkadir M; Fontanet A L; Petros B; Hamann D; Koot M; Roos M T; Schellekens P T; Miedema F; Rinke de Wit T F
Reduced naive and increased activated CD4 and CD8 cells in healthy adult Ethiopians compared with their Dutch counterparts.
Clinical and experimental immunology 1999;115(3):443-50.
1999: Pakker N G; Kroon E D; Roos M T; Otto S A; Hall D; Wit F W; Hamann D; van der Ende M E; Claessen F A; Kauffmann R H; Koopmans P P; Kroon F P; ten Napel C H; Sprenger H G; Weigel H M; Montaner J S; Lange J M; Reiss P; Schellekens P T; Miedema F
Immune restoration does not invariably occur following long-term HIV-1 suppression during antiretroviral therapy. INCAS Study Group.
AIDS (London, England) 1999;13(2):203-12.
1999: Foudraine N A; Hovenkamp E; Notermans D W; Meenhorst P L; Klein M R; Lange J M; Miedema F; Reiss P
Immunopathology as a result of highly active antiretroviral therapy in HIV-1-infected patients.
AIDS (London, England) 1999;13(2):177-84.
1999: Wolthers K C; Otto S A; Wisman G B; Fleury S; Reiss P; ten Kate R W; van der Zee A G; Miedema F
Normal T-cell telomerase activity and upregulation in human immunodeficiency virus-1 infection.
Blood 1999;93(3):1011-9.
1999: Clark D R; de Boer R J; Wolthers K C; Miedema F
T cell dynamics in HIV-1 infection.
Advances in immunology 1999;73():301-27.
1998: Kostense S; Raaphorst F M; Notermans D W; Joling J; Hooibrink B; Pakker N G; Danner S A; Teale J M; Miedema F
Diversity of the T-cell receptor BV repertoire in HIV-1-infected patients reflects the biphasic CD4+ T-cell repopulation kinetics during highly active antiretroviral therapy.
AIDS (London, England) 1998;12(18):F235-40.
1998: Kroon F P; Rimmelzwaan G F; Roos M T; Osterhaus A D; Hamann D; Miedema F; van Dissel J T
Restored humoral immune response to influenza vaccination in HIV-infected adults treated with highly active antiretroviral therapy.
AIDS (London, England) 1998;12(17):F217-23.
1998: Cohen Stuart J W; Boucher C A; Roos M; Miedema F; Borleffs J C; Hamman D
[Increased serum level of naive CD8+-T-cells during intensive antiretroviral therapy]
Nederlands tijdschrift voor geneeskunde 1998;142(40):2230-1.
1998: Maas J J; Roos M T; Keet I P; Mensen E A; Krol A; Veenstra J; Schellekens P T; Jurriaans S; Coutinho R A; Miedema F
In vivo delayed-type hypersensitivity skin test anergy in human immunodeficiency virus type 1 infection is associated with T cell nonresponsiveness in vitro.
The Journal of infectious diseases 1998;178(4):1024-9.
1998: Pontesilli O; Klein M R; Kerkhof-Garde S R; Pakker N G; de Wolf F; Schuitemaker H; Miedema F
Longitudinal analysis of human immunodeficiency virus type 1-specific cytotoxic T lymphocyte responses: a predominant gag-specific response is associated with nonprogressive infection.
The Journal of infectious diseases 1998;178(4):1008-18.
1998: Roos M T; Prins M; Koot M; de Wolf F; Bakker M; Coutinho R A; Miedema F; Schellekens P T
Low T-cell responses to CD3 plus CD28 monoclonal antibodies are predictive of development of AIDS.
AIDS (London, England) 1998;12(14):1745-51.
1998: Klein M R; van der Burg S H; Hovenkamp E; Holwerda A M; Drijfhout J W; Melief C J; Miedema F
Characterization of HLA-B57-restricted human immunodeficiency virus type 1 Gag- and RT-specific cytotoxic T lymphocyte responses.
The Journal of general virology 1998;79 ( Pt 9)():2191-201.
1998: Klein M R; van der Burg S H; Pontesilli O; Miedema F
Cytotoxic T lymphocytes in HIV-1 infection: a killing paradox?
Immunology today 1998;19(7):317-24.
1998: Fleury S; de Boer R J; Rizzardi G P; Wolthers K C; Otto S A; Welbon C C; Graziosi C; Knabenhans C; Soudeyns H; Bart P A; Gallant S; Corpataux J M; Gillet M; Meylan P; Schnyder P; Meuwly J Y; Spreen W; Glauser M P; Miedema F; Pantaleo G
Limited CD4+ T-cell renewal in early HIV-1 infection: effect of highly active antiretroviral therapy.
Nature medicine 1998;4(7):794-801.
1998: Pakker N G; Notermans D W; de Boer R J; Roos M T; de Wolf F; Hill A; Leonard J M; Danner S A; Miedema F; Schellekens P T
Biphasic kinetics of peripheral blood T cells after triple combination therapy in HIV-1 infection: a composite of redistribution and proliferation.
Nature medicine 1998;4(2):208-14.
1997: Pakker N G; Roos M T; van Leeuwen R; de Jong M D; Koot M; Reiss P; Lange J M; Miedema F; Danner S A; Schellekens P T
Patterns of T-cell repopulation, virus load reduction, and restoration of T-cell function in HIV-infected persons during therapy with different antiretroviral agents.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1997;16(5):318-26.
1997: de Wolf F; Spijkerman I; Schellekens P T; Langendam M; Kuiken C; Bakker M; Roos M; Coutinho R; Miedema F; Goudsmit J
AIDS prognosis based on HIV-1 RNA, CD4+ T-cell count and function: markers with reciprocal predictive value over time after seroconversion.
AIDS (London, England) 1997;11(15):1799-806.
1997: de Roda Husman A M; Koot M; Cornelissen M; Keet I P; Brouwer M; Broersen S M; Bakker M; Roos M T; Prins M; de Wolf F; Coutinho R A; Miedema F; Goudsmit J; Schuitemaker H
Association between CCR5 genotype and the clinical course of HIV-1 infection.
Annals of internal medicine 1997;127(10):882-90.
1997: Koot M; van 't Wout A B; Miedema F; Schuitemaker H
Use of Immunological and Viral Parameters to Predict Progression of HIV Infection During Natural Course and Antiretroviral Treatment.
BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 1997;8(4):243-9.
1997: van der Burg S H; Klein M R; Pontesilli O; Holwerda A M; Drijfhout J W; Kast W M; Miedema F; Melief C J
HIV-1 reverse transcriptase-specific CTL against conserved epitopes do not protect against progression to AIDS.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(7):3648-54.
1997: Spijkerman I J; Prins M; Goudsmit J; Veugelers P J; Coutinho R A; Miedema F; de Wolf F
Early and late HIV-1 RNA level and its association with other markers and disease progression in long-term AIDS-free homosexual men.
AIDS (London, England) 1997;11(11):1383-8.
1997: Keet I P; Janssen M; Veugelers P J; Miedema F; Klein M R; Goudsmit J; Coutinho R A; de Wolf F
Longitudinal analysis of CD4 T cell counts, T cell reactivity, and human immunodeficiency virus type 1 RNA levels in persons remaining AIDS-free despite CD4 cell counts <200 for >5 years.
The Journal of infectious diseases 1997;176(3):665-71.
1997: van Baalen C A; Pontesilli O; Huisman R C; Geretti A M; Klein M R; de Wolf F; Miedema F; Gruters R A; Osterhaus A D
Human immunodeficiency virus type 1 Rev- and Tat-specific cytotoxic T lymphocyte frequencies inversely correlate with rapid progression to AIDS.
The Journal of general virology 1997;78 ( Pt 8)():1913-8.
1997: Wolthers K C; Otto S A; Lens S M; Van Lier R A; Miedema F; Meyaard L
Functional B cell abnormalities in HIV type 1 infection: role of CD40L and CD70.
AIDS research and human retroviruses 1997;13(12):1023-9.
1997: Pontesilli O; Klein M R; Kerkhof-Garde S R; Pakker N G; de Wolf F; Schuitemaker H; Miedema F
Kinetics of immune functions and virus replication during HIV-1 infection.
Immunology letters 1997;57(1-3):125-30.
1997: Kootstra N A; Miedema F; Schuitemaker H
Analysis of CD8+ T lymphocyte-mediated nonlytic suppression of autologous and heterologous primary human immunodeficiency virus type 1 isolates.
AIDS research and human retroviruses 1997;13(8):685-93.
1997: Veenstra J; Veugelers P J; Keet I P; van der Ven A J; Miedema F; Lange J M; Coutinho R A
Rapid disease progression in human immunodeficiency virus type 1-infected individuals with adverse reactions to trimethoprim-sulfamethoxazole prophylaxis.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 1997;24(5):936-41.
1997: Kersten M J; Klein M R; Holwerda A M; Miedema F; van Oers M H
Epstein-Barr virus-specific cytotoxic T cell responses in HIV-1 infection: different kinetics in patients progressing to opportunistic infection or non-Hodgkin's lymphoma.
The Journal of clinical investigation 1997;99(7):1525-33.
1997: Klein M R; Veenstra J; Holwerda A M; Roos M T; Gow I; Patou G; Coutinho R A; De Wolf F; Miedema F
Gag-specific immune responses after immunization with p17/p24:Ty virus-like particles in HIV type 1-seropositive individuals.
AIDS research and human retroviruses 1997;13(5):393-9.
1997: Meyaard L; Hovenkamp E; Pakker N; van der Pouw Kraan T C; Miedema F
Interleukin-12 (IL-12) production in whole blood cultures from human immunodeficiency virus-infected individuals studied in relation to IL-10 and prostaglandin E2 production.
Blood 1997;89(2):570-6.
1997: Brinkman B M; Keet I P; Miedema F; Verweij C L; Klein M R
Polymorphisms within the human tumor necrosis factor-alpha promoter region in human immunodeficiency virus type 1-seropositive persons.
The Journal of infectious diseases 1997;175(1):188-90.
1997: Meyaard L; Miedema F
Immune dysregulation and CD4+ T cell loss in HIV-1 infection.
Springer seminars in immunopathology 1997;18(3):285-303.
1996: Keet I P; Veugelers P J; Koot M; de Weerd M H; Roos M T; Miedema F; de Wolf F; Goudsmit J; Coutinho R A
Temporal trends of the natural history of HIV-1 infection following seroconversion between 1984 and 1993.
AIDS (London, England) 1996;10(13):1601-2.
1996: Meyaard L; Fouchier R A; Brouwer M; Hovenkamp E; Miedema F
Syncytium-inducing HIV-1 variants replicate equally well in all types of T-helper cell clones.
AIDS (London, England) 1996;10(13):1598-600.
1996: Wolthers K C; Bea G; Wisman A; Otto S A; de Roda Husman A M; Schaft N; de Wolf F; Goudsmit J; Coutinho R A; van der Zee A G; Meyaard L; Miedema F
T cell telomere length in HIV-1 infection: no evidence for increased CD4+ T cell turnover.
Science (New York, N.Y.) 1996;274(5292):1543-7.
1996: Roos M T; Miedema F; Meinesz A P; De Leeuw N A; Pakker N G; Lange J M; Coutinho R A; Schellekens P T
Low T cell reactivity to combined CD3 plus CD28 stimulation is predictive for progression to AIDS: correlation with decreased CD28 expression.
Clinical and experimental immunology 1996;105(3):409-15.
1996: Meyaard L; Hovenkamp E; Keet I P; Hooibrink B; de Jong I H; Otto S A; Miedema F
Single cell analysis of IL-4 and IFN-gamma production by T cells from HIV-infected individuals: decreased IFN-gamma in the presence of preserved IL-4 production.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2712-8.
1996: Wolthers K C; Otto S A; Lens S M; Kolbach D N; van Lier R A; Miedema F; Meyaard L
Increased expression of CD80, CD86 and CD70 on T cells from HIV-infected individuals upon activation in vitro: regulation by CD4+ T cells.
European journal of immunology 1996;26(8):1700-6.
1996: van Baalen C A; Klein M R; Huisman R C; Dings M E; Kerkhof Garde S R; Geretti A M; Gruters R; van Els C A; Miedema F; Osterhaus A D
Fine-specificity of cytotoxic T lymphocytes which recognize conserved epitopes of the Gag protein of human immunodeficiency virus type 1.
The Journal of general virology 1996;77 ( Pt 8)():1659-65.
1996: Miedema F; Klein M R
AIDS pathogenesis: a finite immune response to blame?
Science (New York, N.Y.) 1996;272(5261):505-6.
1996: Meyaard L; Hovenkamp E; Otto S A; Miedema F
IL-12-induced IL-10 production by human T cells as a negative feedback for IL-12-induced immune responses.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(8):2776-82.
1995: Spijkerman I J; Koot M; Prins M; Keet I P; van den Hoek A J; Miedema F; Coutinho R A
Lower prevalence and incidence of HIV-1 syncytium-inducing phenotype among injecting drug users compared with homosexual men.
AIDS (London, England) 1995;9(9):1085-92.
1995: Schuitemaker H; Fouchier R A; Broersen S; Groenink M; Koot M; van 't Wout A B; Huisman H G; Tersmette M; Miedema F
Envelope V2 configuration and HIV-1 phenotype: clarification.
Science (New York, N.Y.) 1995;268(5207):115.
1995: Hogervorst E; Jurriaans S; de Wolf F; van Wijk A; Wiersma A; Valk M; Roos M; van Gemen B; Coutinho R; Miedema F
Predictors for non- and slow progression in human immunodeficiency virus (HIV) type 1 infection: low viral RNA copy numbers in serum and maintenance of high HIV-1 p24-specific but not V3-specific antibody levels.
The Journal of infectious diseases 1995;171(4):811-21.
1995: Klein M R; van Baalen C A; Holwerda A M; Kerkhof Garde S R; Bende R J; Keet I P; Eeftinck-Schattenkerk J K; Osterhaus A D; Schuitemaker H; Miedema F
Kinetics of Gag-specific cytotoxic T lymphocyte responses during the clinical course of HIV-1 infection: a longitudinal analysis of rapid progressors and long-term asymptomatics.
The Journal of experimental medicine 1995;181(4):1365-72.
1995: Roos M T; Miedema F; Koot M; Tersmette M; Schaasberg W P; Coutinho R A; Schellekens P T
T cell function in vitro is an independent progression marker for AIDS in human immunodeficiency virus-infected asymptomatic subjects.
The Journal of infectious diseases 1995;171(3):531-6.
1995: van der Burg S H; Klein M R; van de Velde C J; Kast W M; Miedema F; Melief C J
Induction of a primary human cytotoxic T-lymphocyte response against a novel conserved epitope in a functional sequence of HIV-1 reverse transcriptase.
AIDS (London, England) 1995;9(2):121-7.
1995: Meyaard L; Kuiper H; Otto S A; Wolthers K C; van Lier R A; Miedema F
Evidence for intact costimulation via CD28 and CD27 molecules in hyporesponsive T cells from human immunodeficiency virus-infected individuals.
European journal of immunology 1995;25(1):232-7.
1995: Meyaard L; Miedema F
Programmed death of T cells in HIV infection: result of immune activation?
Current topics in microbiology and immunology 1995;200():213-21.
1995: Schellekens P T; Koot M; Roos M T; Tersmette M; Miedema F
Immunologic and virologic markers determining progression to AIDS.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1995;10 Suppl 2():S62-6.
1994: Meyaard L; Otto S A; Keet I P; van Lier R A; Miedema F
Changes in cytokine secretion patterns of CD4+ T-cell clones in human immunodeficiency virus infection.
Blood 1994;84(12):4262-8.
1994: Schuitemaker H; Kootstra N A; Fouchier R A; Hooibrink B; Miedema F
Productive HIV-1 infection of macrophages restricted to the cell fraction with proliferative capacity.
The EMBO journal 1994;13(24):5929-36.
1994: van't Wout A B; Kootstra N A; Mulder-Kampinga G A; Albrecht-van Lent N; Scherpbier H J; Veenstra J; Boer K; Coutinho R A; Miedema F; Schuitemaker H
Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission.
The Journal of clinical investigation 1994;94(5):2060-7.
1994: Meyaard L; Otto S A; Hooibrink B; Miedema F
Quantitative analysis of CD4+ T cell function in the course of human immunodeficiency virus infection. Gradual decline of both naive and memory alloreactive T cells.
The Journal of clinical investigation 1994;94(5):1947-52.
1994: Kootstra N A; van 't Wout A; Huisman H G; Miedema F; Schuitemaker H
Interference of interleukin-10 with human immunodeficiency virus type 1 replication in primary monocyte-derived macrophages.
Journal of virology 1994;68(11):6967-75.
1994: Keet I P; Krol A; Koot M; Roos M T; de Wolf F; Miedema F; Coutinho R A
Predictors of disease progression in HIV-infected homosexual men with CD4+ cells < 200 x 10(6)/l but free of AIDS-defining clinical disease.
AIDS (London, England) 1994;8(11):1577-83.
1994: Roos M T; de Leeuw N A; Claessen F A; Huisman H G; Kootstra N A; Meyaard L; Schellekens P T; Schuitemaker H; Miedema F
Viro-immunological studies in acute HIV-1 infection.
AIDS (London, England) 1994;8(11):1533-8.
1994: Miedema F; Meyaard L; Koot M; Klein M R; Roos M T; Groenink M; Fouchier R A; Van't Wout A B; Tersmette M; Schellekens P T
Changing virus-host interactions in the course of HIV-1 infection.
Immunological reviews 1994;140():35-72.
1994: Klein M R; Keet I P; D'Amaro J; Bende R J; Hekman A; Mesman B; Koot M; de Waal L P; Coutinho R A; Miedema F
Associations between HLA frequencies and pathogenic features of human immunodeficiency virus type 1 infection in seroconverters from the Amsterdam cohort of homosexual men.
The Journal of infectious diseases 1994;169(6):1244-9.
1994: Keet I P; Krol A; Klein M R; Veugelers P; de Wit J; Roos M; Koot M; Goudsmit J; Miedema F; Coutinho R A
Characteristics of long-term asymptomatic infection with human immunodeficiency virus type 1 in men with normal and low CD4+ cell counts.
The Journal of infectious diseases 1994;169(6):1236-43.
1994: van Kemenade F J; Tellegen E; Maurice M M; Lankester A C; Kuijpers T W; Brouwer M; de Jong R; Miedema F; van Lier R A
Simultaneous regulation of CD2 adhesion and signaling functions by a novel CD2 monoclonal antibody.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4425-32.
1994: Meyaard L; Otto S A; Keet I P; Roos M T; Miedema F
Programmed death of T cells in human immunodeficiency virus infection. No correlation with progression to disease.
The Journal of clinical investigation 1994;93(3):982-8.
1994: Mientjes G H; Miedema F; van den Hoek J A; Coutinho R A
Immunologic alterations in splenectomized HIV-infected intravenous drug users.
AIDS (London, England) 1994;8(2):269-71.
1994: Schuitemaker H; Koot M; Miedema F
Recent development on research in AIDS pathogenesis.
Vox sanguinis 1994;67 Suppl 3():133-6.
1993: Schuitemaker H; Meyaard L; Kootstra N A; Dubbes R; Otto S A; Tersmette M; Heeney J L; Miedema F
Lack of T cell dysfunction and programmed cell death in human immunodeficiency virus type 1-infected chimpanzees correlates with absence of monocytotropic variants.
The Journal of infectious diseases 1993;168(5):1140-7.
1993: Mientjes G H; van Ameijden E J; van den Hoek A J; Goudsmit J; Miedema F; Coutinho R A
Progression of HIV infection among injecting drug users: indications for a lower rate of progression among those who have frequently borrowed injecting equipment.
AIDS (London, England) 1993;7(10):1363-70.
1993: Koot M; Schellekens P T; Mulder J W; Lange J M; Roos M T; Coutinho R A; Tersmette M; Miedema F
Viral phenotype and T cell reactivity in human immunodeficiency virus type 1-infected asymptomatic men treated with zidovudine.
The Journal of infectious diseases 1993;168(3):733-6.
1993: Schuitemaker H; Groenink M; Meyaard L; Kootstra N A; Fouchier R A; Gruters R A; Huisman H G; Tersmette M; Miedema F
Early replication steps but not cell type-specific signalling of the viral long terminal repeat determine HIV-1 monocytotropism.
AIDS research and human retroviruses 1993;9(7):669-75.
1993: Groenink M; Fouchier R A; Broersen S; Baker C H; Koot M; van't Wout A B; Huisman H G; Miedema F; Tersmette M; Schuitemaker H
Relation of phenotype evolution of HIV-1 to envelope V2 configuration.
Science (New York, N.Y.) 1993;260(5113):1513-6.
1993: van Baalen C A; Klein M R; Geretti A M; Keet R I; Miedema F; van Els C A; Osterhaus A D
Selective in vitro expansion of HLA class I-restricted HIV-1 Gag-specific CD8+ T cells: cytotoxic T-lymphocyte epitopes and precursor frequencies.
AIDS (London, England) 1993;7(6):781-6.
1993: Koot M; Keet I P; Vos A H; de Goede R E; Roos M T; Coutinho R A; Miedema F; Schellekens P T; Tersmette M
Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS.
Annals of internal medicine 1993;118(9):681-8.
1993: Meyaard L; Schuitemaker H; Miedema F
T-cell dysfunction in HIV infection: anergy due to defective antigen-presenting cell function?
Immunology today 1993;14(4):161-4.
1993: van Kemenade F J; Kuijpers K C; de Waal-Malefijt R; van Lier R A; Miedema F
Skewing to the LFA-3 adhesion pathway by influenza infection of antigen-presenting cells.
European journal of immunology 1993;23(3):635-9.
1993: Schuitemaker H; Groenink M; Tersmette M; Miedema F
HIV tropism.
Nature 1993;361(6410):310.
1993: Keet I P; Krijnen P; Koot M; Lange J M; Miedema F; Goudsmit J; Coutinho R A
Predictors of rapid progression to AIDS in HIV-1 seroconverters.
AIDS (London, England) 1993;7(1):51-7.
1992: Mientjes G H; van Ameijden E J; Roos M T; de Leeuw N A; van den Hoek J A; Coutinho R A; Miedema F F
Large diurnal variation in CD4 cell count and T-cell function among drug users: implications for clinical practice and epidemiological studies.
AIDS (London, England) 1992;6(11):1269-72.
1992: Boucher C A; Lange J M; Miedema F F; Weverling G J; Koot M; Mulder J W; Goudsmit J; Kellam P; Larder B A; Tersmette M
HIV-1 biological phenotype and the development of zidovudine resistance in relation to disease progression in asymptomatic individuals during treatment.
AIDS (London, England) 1992;6(11):1259-64.
1992: Meyaard L; Otto S A; Schuitemaker H; Miedema F
Effects of HIV-1 Tat protein on human T cell proliferation.
European journal of immunology 1992;22(10):2729-32.
1992: de Jong R; Brouwer M; Kuiper H M; Hooibrink B; Miedema F; van Lier R A
Maturation- and differentiation-dependent responsiveness of human CD4+ T helper subsets.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2795-802.
1992: Kuijpers K C; van Kemenade F J; Hooibrink B; Neefjes J J; Lucas C J; van Lier R A; Miedema F
HLA class I and II molecules present influenza virus antigens with different kinetics.
European journal of immunology 1992;22(9):2339-45.
1992: Schuitemaker H; Kootstra N A; Groenink M; De Goede R E; Miedema F; Tersmette M
Differential tropism of clinical HIV-1 isolates for primary monocytes and promonocytic cell lines.
AIDS research and human retroviruses 1992;8(9):1679-82.
1992: Schellekens P T; Tersmette M; Roos M T; Keet R P; de Wolf F; Coutinho R A; Miedema F
Biphasic rate of CD4+ cell count decline during progression to AIDS correlates with HIV-1 phenotype.
AIDS (London, England) 1992;6(7):665-9.
1992: Meyaard L; Otto S A; Jonker R R; Mijnster M J; Keet R P; Miedema F
Programmed death of T cells in HIV-1 infection.
Science (New York, N.Y.) 1992;257(5067):217-9.
1992: Fouchier R A; Groenink M; Kootstra N A; Tersmette M; Huisman H G; Miedema F; Schuitemaker H
Phenotype-associated sequence variation in the third variable domain of the human immunodeficiency virus type 1 gp120 molecule.
Journal of virology 1992;66(5):3183-7.
1992: Schuitemaker H; Kootstra N A; Koppelman M H; Bruisten S M; Huisman H G; Tersmette M; Miedema F
Proliferation-dependent HIV-1 infection of monocytes occurs during differentiation into macrophages.
The Journal of clinical investigation 1992;89(4):1154-60.
1992: De Jong R; Brouwer M; Hooibrink B; Van der Pouw-Kraan T; Miedema F; Van Lier R A
The CD27- subset of peripheral blood memory CD4+ lymphocytes contains functionally differentiated T lymphocytes that develop by persistent antigenic stimulation in vivo.
European journal of immunology 1992;22(4):993-9.
1992: Schuitemaker H; Koot M; Kootstra N A; Dercksen M W; de Goede R E; van Steenwijk R P; Lange J M; Schattenkerk J K; Miedema F; Tersmette M
Biological phenotype of human immunodeficiency virus type 1 clones at different stages of infection: progression of disease is associated with a shift from monocytotropic to T-cell-tropic virus population.
Journal of virology 1992;66(3):1354-60.
1992: Roos M T; Lange J M; de Goede R E; Coutinho R A; Schellekens P T; Miedema F; Tersmette M
Viral phenotype and immune response in primary human immunodeficiency virus type 1 infection.
The Journal of infectious diseases 1992;165(3):427-32.
1992: Koot M; Vos A H; Keet R P; de Goede R E; Dercksen M W; Terpstra F G; Coutinho R A; Miedema F; Tersmette M
HIV-1 biological phenotype in long-term infected individuals evaluated with an MT-2 cocultivation assay.
AIDS (London, England) 1992;6(1):49-54.
1992: Miedema F
Immunological abnormalities in the natural history of HIV infection: mechanisms and clinical relevance.
Immunodeficiency reviews 1992;3(3):173-93.
1991: de Jong R; Stokkers P; Lamme E; Kool J M; Borst F; Brouwer M; Miedema F; van Lier R A
Regulation of T-cell differentiation by CD2 and CD28 accessory molecules.
Immunology 1991;74(2):175-82.
1991: Gruters R A; Terpstra F G; De Goede R E; Mulder J W; De Wolf F; Schellekens P T; Van Lier R A; Tersmette M; Miedema F
Immunological and virological markers in individuals progressing from seroconversion to AIDS.
AIDS (London, England) 1991;5(7):837-44.
1991: Kuijpers K C; Treep-Van Leeuwen P; Miedema F; Lucas C J
Allo-cross-reactivity of a human neuraminidase-specific T cell clone dependent on presentation of an endogenous B cell-specific antigen.
European journal of immunology 1991;21(6):1453-60.
1991: de Jong R; Brouwer M; Miedema F; van Lier R A
Human CD8+ T lymphocytes can be divided into CD45RA+ and CD45RO+ cells with different requirements for activation and differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2088-94.
1991: Schuitemaker H; Kootstra N A; de Goede R E; de Wolf F; Miedema F; Tersmette M
Monocytotropic human immunodeficiency virus type 1 (HIV-1) variants detectable in all stages of HIV-1 infection lack T-cell line tropism and syncytium-inducing ability in primary T-cell culture.
Journal of virology 1991;65(1):356-63.
1991: Gruters R A; Otto S A; Al B J; Verhoeven A J; Verweij C L; Van Lier R A; Miedema F
Non-mitogenic T cell activation signals are sufficient for induction of human immunodeficiency virus transcription.
European journal of immunology 1991;21(1):167-72.
1991: Mientjes G H; Miedema F; van Ameijden E J; van den Hoek A A; Schellekens P T; Roos M T; Coutinho R A
Frequent injecting impairs lymphocyte reactivity in HIV-positive and HIV-negative drug users.
AIDS (London, England) 1991;5(1):35-41.
1991: Gruters R A; Terpstra F G; Lange J M; Roos M T; Harkema T; Mulder J W; De Wolf F; Schellekens P T; Miedema F
Differences in clinical course in zidovudine-treated asymptomatic HIV-infected men associated with T-cell function at intake.
AIDS (London, England) 1991;5(1):43-7.
1990: Schuitemaker H; Kootstra N A; van Oers M H; van Lambalgen R; Tersmette M; Miedema F
Induction of monocyte proliferation and HIV expression by IL-3 does not interfere with anti-viral activity of zidovudine.
Blood 1990;76(8):1490-3.
1990: De Jong R; Brouwer M; Rebel V I; Van Seventer G A; Miedema F; Van Lier R A
Generation of alloreactive cytolytic T lymphocytes by immobilized anti-CD3 monoclonal antibodies. Analysis of requirements for human cytolytic T-lymphocyte differentiation.
Immunology 1990;70(3):357-64.
1990: van Noesel C J; Gruters R A; Terpstra F G; Schellekens P T; van Lier R A; Miedema F
Functional and phenotypic evidence for a selective loss of memory T cells in asymptomatic human immunodeficiency virus-infected men.
The Journal of clinical investigation 1990;86(1):293-9.
1990: Gruters R A; Terpstra F G; De Jong R; Van Noesel C J; Van Lier R A; Miedema F
Selective loss of T cell functions in different stages of HIV infection. Early loss of anti-CD3-induced T cell proliferation followed by decreased anti-CD3-induced cytotoxic T lymphocyte generation in AIDS-related complex and AIDS.
European journal of immunology 1990;20(5):1039-44.
1990: Kuijpers K C; Kuijpers T W; Zeijlemaker W P; Lucas C J; van Lier R A; Miedema F
Analysis of the role of leukocyte function-associated antigen-1 in activation of human influenza virus-specific T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3281-7.
1990: Schellekens P T; Roos M T; De Wolf F; Lange J M; Miedema F
Low T-cell responsiveness to activation via CD3/TCR is a prognostic marker for acquired immunodeficiency syndrome (AIDS) in human immunodeficiency virus-1 (HIV-1)-infected men.
Journal of clinical immunology 1990;10(2):121-7.
1990: Tersmette M; Miedema F
Interactions between HIV and the host immune system in the pathogenesis of AIDS.
AIDS (London, England) 1990;4 Suppl 1():S57-66.
1989: Tersmette M; Winkel I N; Groenink M; Gruters R A; Spence R P; Saman E; Van Der Groen G; Miedema F; Huisman J G
Detection and subtyping of HIV-1 isolates with a panel of characterized monoclonal antibodies to HIV p24gag.
Virology 1989;171(1):149-55.
1989: Tersmette M; Gruters R A; de Wolf F; de Goede R E; Lange J M; Schellekens P T; Goudsmit J; Huisman H G; Miedema F
Evidence for a role of virulent human immunodeficiency virus (HIV) variants in the pathogenesis of acquired immunodeficiency syndrome: studies on sequential HIV isolates.
Journal of virology 1989;63(5):2118-25.
1989: Terpstra F G; Al B J; Roos M T; De Wolf F; Goudsmit J; Schellekens P T; Miedema F
Longitudinal study of leukocyte functions in homosexual men seroconverted for HIV: rapid and persistent loss of B cell function after HIV infection.
European journal of immunology 1989;19(4):667-73.
1989: Tersmette M; van Dongen J J; Clapham P R; de Goede R E; Wolvers-Tettero I L; Geurts van Kessel A; Huisman J G; Weiss R A; Miedema F
Human immunodeficiency virus infection studied in CD4-expressing human-murine T-cell hybrids.
Virology 1989;168(2):267-73.
1988: Miedema F; Petit A J; Terpstra F G; Schattenkerk J K; de Wolf F; Al B J; Roos M; Lange J M; Danner S A; Goudsmit J
Immunological abnormalities in human immunodeficiency virus (HIV)-infected asymptomatic homosexual men. HIV affects the immune system before CD4+ T helper cell depletion occurs.
The Journal of clinical investigation 1988;82(6):1908-14.
1988: Rotteveel F T; Kokkelink I; van Lier R A; Kuenen B; Meager A; Miedema F; Lucas C J
Clonal analysis of functionally distinct human CD4+ T cell subsets.
The Journal of experimental medicine 1988;168(5):1659-73.
1988: Sauerwein R W; De Rie M A; van der Meer W G; Miedema F; Aarden L A
Regulation of malignant B-cell proliferation by direct binding of anti-HLA class-II antibodies.
Cellular immunology 1988;114(2):424-31.
1988: Tersmette M; de Goede R E; Al B J; Winkel I N; Gruters R A; Cuypers H T; Huisman H G; Miedema F
Differential syncytium-inducing capacity of human immunodeficiency virus isolates: frequent detection of syncytium-inducing isolates in patients with acquired immunodeficiency syndrome (AIDS) and AIDS-related complex.
Journal of virology 1988;62(6):2026-32.
1988: van Noesel C; Miedema F; Brouwer M; de Rie M A; Aarden L A; van Lier R A
Regulatory properties of LFA-1 alpha and beta chains in human T-lymphocyte activation.
Nature 1988;333(6176):850-2.
1988: Van Lier R A; Pool M O; Kabel P; Mous S; Terpstra F; De Rie M A; Melief C J; Miedema F
Anti-CD27 monoclonal antibodies identify two functionally distinct subpopulations within the CD4+ T cell subset.
European journal of immunology 1988;18(5):811-6.
1988: Petit A J; Tersmette M; Terpstra F G; de Goede R E; van Lier R A; Miedema F
Decreased accessory cell function by human monocytic cells after infection with HIV.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(5):1485-9.
1988: Sauerwein R W; Van der Meer W G; Van Oostveen J W; Miedema F; Aarden L A
Anti-CD3 antibodies induce T helper function for human B cell differentiation in vitro by an interleukin 2-independent pathway.
European journal of immunology 1988;18(1):133-7.
1988: Tersmette M; Lelie P N; van der Poel C L; Wester M R; de Goede R E; Lange J M; Miedema F; Huisman J G
Confirmation of HIV seropositivity: comparison of a novel radioimmunoprecipitation assay to immunoblotting and virus culture.
Journal of medical virology 1988;24(1):109-16.
1987: Gruters R A; Neefjes J J; Tersmette M; de Goede R E; Tulp A; Huisman H G; Miedema F; Ploegh H L
Interference with HIV-induced syncytium formation and viral infectivity by inhibitors of trimming glucosidase.
Nature 1987;330(6143):74-7.
1987: De Rie M A; Kabel P; Sauerwein R W; Van Lier R A; Von dem Borne A E; Melief C J; Miedema F
Anti-HLA-class II monoclonal antibodies inhibit polyclonal B cell differentiation in vitro at the accessory cell level.
European journal of immunology 1987;17(6):881-6.
1987: Petit A J; Terpstra F G; Miedema F
Human immunodeficiency virus infection down-regulates HLA class II expression and induces differentiation in promonocytic U937 cells.
The Journal of clinical investigation 1987;79(6):1883-9.
1987: Huisman J G; Winkel I N; Lelie P N; Tersmette M; Goudsmit J; Miedema F
Detection of early anti-p24 HIV responses in EIA- and immunoblot-negative individuals. Implications for confirmatory testing.
Vox sanguinis 1987;53(1):31-6.
1986: Goudsmit J; Miedema F; Breederveld C; Terpstra F; Roos M; Schellekens P; Melief C
Antibodies to the human T-cell lymphoma/leukemia virus type I in Dutch haemophiliacs.
Vox sanguinis 1986;50(1):12-5.
1985: Miedema F; van Oostveen J W; Terpstra F G; van den Wall Bake A W; Willemze R; Rauws E A; Bieger R; van 't Veer M B; Catovsky D; Melief C J
Analysis of helper activity on pokeweed mitogen- and interleukin 2-driven immunoglobulin synthesis by neoplastic T4+ cells.
The Journal of clinical investigation 1985;76(6):2139-43.
1985: Miedema F; Terpstra F G; Smit J W; van der Veen J P; Melief C J
T gamma lymphocytosis is clinically non-progressive but immunologically heterogeneous.
Clinical and experimental immunology 1985;61(2):440-9.
1985: Miedema F; Tetteroo P A; Terpstra F G; Keizer G; Roos M; Weening R S; Weemaes C M; Roos D; Melief C J
Immunologic studies with LFA-1- and Mo1-deficient lymphocytes from a patient with recurrent bacterial infections.
Journal of immunology (Baltimore, Md. : 1950) 1985;134(5):3075-81.
1985: Miedema F; Van Oostveen J W; Sauerwein R W; Terpstra F G; Aarden L A; Melief C J
Induction of immunoglobulin synthesis by interleukin 2 is T4+/T8- cell dependent. A role for interleukin 2 in the pokeweed mitogen-driven system.
European journal of immunology 1985;15(2):107-12.
1984: Miedema F; Terpstra F G; Smit J W; Daenen S; Gerrits W; Hegde U; Matutes E; Catovsky D; Greaves M F; Melief C J
Functional properties of neoplastic T cells in adult T cell lymphoma/leukemia patients from the Caribbean.
Blood 1984;63(2):477-81.
1982: Rümke H C; Miedema F; ten Berge I J; Terpstra F; van der Reijden H J; van de Griend R J; de Bruin H G; von dem Borne A E; Smit J W; Zeijlemaker W P; Melief C J
Functional properties of T cells in patients with chronic T gamma lymphocytosis and chronic T cell neoplasia.
Journal of immunology (Baltimore, Md. : 1950) 1982;129(1):419-26.

Sign-in to see more