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Patrick Beardsley

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Keith L Shelton; Elizabeth S Hendrick; Patrick M Beardsley
Efficacy of buspirone for attenuating cocaine and methamphetamine reinstatement in rats.
Sarah E Snider; Elizabeth S Hendrick; Patrick M Beardsley
Glial cell modulators attenuate methamphetamine self-administration in the rat.
Sarah E Snider; Edwin J C G van den Oord; Sarah A Vunck; Daniel E Adkins; Joseph L McClay; Patrick M Beardsley
The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice.

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All Publications

2013: Keith L Shelton; Elizabeth S Hendrick; Patrick M Beardsley
Efficacy of buspirone for attenuating cocaine and methamphetamine reinstatement in rats.
Drug and alcohol dependence 2013;129(3):210-6.
2013: Sarah E Snider; Elizabeth S Hendrick; Patrick M Beardsley
Glial cell modulators attenuate methamphetamine self-administration in the rat.
European journal of pharmacology 2013;701(1-3):124-30.
2012: Sarah E Snider; Edwin J C G van den Oord; Sarah A Vunck; Daniel E Adkins; Joseph L McClay; Patrick M Beardsley
The glial cell modulators, ibudilast and its amino analog, AV1013, attenuate methamphetamine locomotor activity and its sensitization in mice.
European journal of pharmacology 2012;679(1-3):75-80.
2012: Patrick M Beardsley; Keith L Shelton
Prime-, stress-, and cue-induced reinstatement of extinguished drug-reinforced responding in rats: cocaine as the prototypical drug of abuse.
Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.] 2012;Chapter 9():Unit 9.39.
2011: Joseph L McClay; Daniel E Adkins; Karolina Aberg; József Bukszár; Amit N Khachane; Richard S E Keefe; Diana O Perkins; Joseph P McEvoy; T Scott Stroup; Robert Vann; Patrick M Beardsley; Jeffrey A Lieberman; Patrick F Sullivan; Edwin J C G van den Oord
Genome-wide pharmacogenomic study of neurocognition as an indicator of antipsychotic treatment response in schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2011;36(3):616-26.
2010: Angela M Batman; Aloke Dutta; Maarten E A Reith; Patrick M Beardsley
The selective dopamine uptake inhibitor, D-84, suppresses cocaine self-administration, but does not occasion cocaine-like levels of generalization.
European journal of pharmacology 2010;648(1-3):127-32.
2010: Patrick M Beardsley; Keith L Shelton; Elizabeth Hendrick; Kirk W Johnson
The glial cell modulator and phosphodiesterase inhibitor, AV411 (ibudilast), attenuates prime- and stress-induced methamphetamine relapse.
European journal of pharmacology 2010;637(1-3):102-8.
2010: Patrick M Beardsley; Gerald T Pollard; James L Howard; F Ivy Carroll
Effectiveness of analogs of the kappa opioid receptor antagonist (3R)-7-hydroxy-N-((1S)-1-{[(3R,4R)-4-(3-hydroxyphenyl)-3,4-dimethyl-1-piperidinyl]methyl}-2-methylpropyl)-1,2,3,4-tetrahydro-3-isoquinolinecarboxamide (JDTic) to reduce U50,488-induced diuresis and stress-induced cocaine reinstatement in rats.
Psychopharmacology 2010;210(2):189-98.
2010: Darlene H Brunzell; Karen E Boschen; Elizabeth S Hendrick; Patrick M Beardsley; J Michael McIntosh
Alpha-conotoxin MII-sensitive nicotinic acetylcholine receptors in the nucleus accumbens shell regulate progressive ratio responding maintained by nicotine.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(3):665-73.
2009: Prashant S Kharkar; Angela M Batman; Juan Zhen; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
Synthesis and biological characterization of (3R,4R)-4-(2-(benzhydryloxy)ethyl)-1-((R)-2-hydroxy-2-phenylethyl)-piperidin-3-ol and its stereoisomers for activity toward monoamine transporters.
ChemMedChem 2009;4(7):1075-85.
2009: Patrick M Beardsley; Brian Thomas; Lance McMahon
Cannabinoid CB1 receptor antagonists as potential pharmacotherapies for drug abuse disorders.
International review of psychiatry (Abingdon, England) 2009;21(2):134-42.
2008: Keith L Shelton; Patrick M Beardsley
Effect of drug-paired exteroceptive stimulus presentations on methamphetamine reinstatement in rats.
Pharmacology, biochemistry, and behavior 2008;90(3):434-40.
2006: Cristina Vargas-Irwin; Edwin J C G van den Oord; Patrick M Beardsley; Jaime R Robles
A method for analyzing strain differences in acquisition of IV cocaine self-administration in mice.
Behavior genetics 2006;36(4):525-35.
2006: Jennifer Newman; Patrick M Beardsley
Effects of memantine, haloperidol, and cocaine on primary and conditioned reinforcement associated with cocaine in rhesus monkeys.
Psychopharmacology 2006;185(2):142-9.
2006: charlie cook; Laura Biddlestone; Andrew Coop; Patrick M Beardsley
Effects of combining ethanol (EtOH) with gamma-hydroxybutyrate (GHB) on the discriminative stimulus, locomotor, and motor-impairing functions of GHB in mice.
Psychopharmacology 2006;185(1):112-22.
2006: Robert Vann; Robert L Balster; Patrick M Beardsley
Dose, duration, and pattern of nicotine administration as determinants of behavioral dependence in rats.
Psychopharmacology 2006;184(3-4):482-93.
2005: Patrick M Beardsley; James L Howard; Keith L Shelton; Frank carroll
Differential effects of the novel kappa opioid receptor antagonist, JDTic, on reinstatement of cocaine-seeking induced by footshock stressors vs cocaine primes and its antidepressant-like effects in rats.
Psychopharmacology 2005;183(1):118-26.
2005: Patrick M Beardsley; Brian Thomas
Current evidence supporting a role of cannabinoid CB1 receptor (CB1R) antagonists as potential pharmacotherapies for drug abuse disorders.
Behavioural pharmacology 2005;16(5-6):275-96.
2005: Angela M Batman; Patrik Munzar; Patrick M Beardsley
Attenuation of nicotine's discriminative stimulus effects in rats and its locomotor activity effects in mice by serotonergic 5-HT2A/2C receptor agonists.
Psychopharmacology 2005;179(2):393-401.
2004: Rohit Kolhatkar; charlie cook; Sujit K Ghorai; Jeffrey Deschamps; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
Further structurally constrained analogues of cis-(6-benzhydrylpiperidin-3-yl)benzylamine with elucidation of bioactive conformation: discovery of 1,4-diazabicyclo[3.3.1]nonane derivatives and evaluation of their biological properties for the monoamine transporters.
Journal of medicinal chemistry 2004;47(21):5101-13.
2004: Keith L Shelton; Elizabeth Hendrick; Patrick M Beardsley
Interaction of noncontingent cocaine and contingent drug-paired stimuli on cocaine reinstatement.
European journal of pharmacology 2004;497(1):35-40.
2004: Patrick M Beardsley; Mario D Aceto; charlie cook; Edward R Bowman; Jennifer Newman; Louis S Harris
Discriminative stimulus, reinforcing, physical dependence, and antinociceptive effects of oxycodone in mice, rats, and rhesus monkeys.
Experimental and clinical psychopharmacology 2004;12(3):163-72.
2004: charlie cook; Patrick M Beardsley
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: II. Effects of dopamine D2/3 agonists.
Behavioural pharmacology 2004;15(1):75-83.
2004: charlie cook; Patrick M Beardsley
Modulation of the discriminative stimulus effects of mu opioid agonists in rats: I. Effects of dopamine D2/3 antagonists.
Behavioural pharmacology 2004;15(1):65-74.
2004: charlie cook; Jennifer Newman; Jennifer C Winfree; Patrick M Beardsley
Modulation of the locomotor activating effects of the noncompetitive NMDA receptor antagonist MK801 by dopamine D2/3 receptor agonists in mice.
Pharmacology, biochemistry, and behavior 2004;77(2):309-18.
2003: charlie cook; Patrick M Beardsley
The modulatory actions of dopamine D2/3 agonists and antagonists on the locomotor-activating effects of morphine and caffeine in mice.
Pharmacology, biochemistry, and behavior 2003;75(2):363-71.
2003: Alan P Kozikowski; Kenneth M Johnson; Olivier Deschaux; Bidhan Bandyopadhyay; Gian Luca Araldi; Gilberto Carmona; Patrik Munzar; Miles P Smith; Robert L Balster; Patrick M Beardsley; Srihari R Tella
Mixed cocaine agonist/antagonist properties of (+)-methyl 4beta-(4-chlorophenyl)-1-methylpiperidine-3alpha-carboxylate, a piperidine-based analog of cocaine.
The Journal of pharmacology and experimental therapeutics 2003;305(1):143-50.
2003: Sujit K Ghorai; Charles Cook; Matthew Davis; Sylesh K Venkataraman; Clifford George; Patrick M Beardsley; Maarten E A Reith; Aloke Dutta
High affinity hydroxypiperidine analogues of 4-(2-benzhydryloxyethyl)-1-(4-fluorobenzyl)piperidine for the dopamine transporter: stereospecific interactions in vitro and in vivo.
Journal of medicinal chemistry 2003;46(7):1220-8.
2002: Patrick M Beardsley; E Ratti; Robert L Balster; J Willetts; David G Trist
The selective glycine antagonist gavestinel lacks phencyclidine-like behavioral effects.
Behavioural pharmacology 2002;13(7):583-92.
2002: Jennifer Newman; Robert Vann; Everette L May; Patrick M Beardsley
Heroin discriminative stimulus effects of methadone, LAAM and other isomers of acetylmethadol in rats.
Psychopharmacology 2002;164(1):108-14.
2002: Catherine B Willmore; Anton Y Bespalov; Patrick M Beardsley
Site-selective N-methyl-D-aspartate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonists produce distinct effects in rats performing complex discriminations.
Neurobiology of learning and memory 2002;78(2):347-64.
2002: charlie cook; Frank carroll; Patrick M Beardsley
RTI 113, a 3-phenyltropane analog, produces long-lasting cocaine-like discriminative stimulus effects in rats and squirrel monkeys.
European journal of pharmacology 2002;442(1-2):93-8.
2002: charlie cook; Mario D Aceto; Andrew Coop; Patrick M Beardsley
Effects of the putative antagonist NCS382 on the behavioral pharmacological actions of gammahydroxybutyrate in mice.
Psychopharmacology 2002;160(1):99-106.
2002: Aloke Dutta; Matthew C Davis; Xiang-Shu Fei; Patrick M Beardsley; charlie cook; Maarten E A Reith
Expansion of structure-activity studies of piperidine analogues of 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine (GBR 12935) compounds by altering substitutions in the N-benzyl moiety and behavioral pharmacology of selected molecules.
Journal of medicinal chemistry 2002;45(3):654-62.
2002: Patrick M Beardsley; Mario E Dance; Robert L Balster; Patrik Munzar
Evaluation of the reinforcing effects of the cannabinoid CB1 receptor antagonist, SR141716, in rhesus monkeys.
European journal of pharmacology 2002;435(2-3):209-16.
2001: charlie cook; I F Carroll; Patrick M Beardsley
Cocaine-like discriminative stimulus effects of novel cocaine and 3-phenyltropane analogs in the rat.
Psychopharmacology 2001;159(1):58-63.
2001: Catherine B Willmore; Anton Y Bespalov; Patrick M Beardsley
Competitive and noncompetitive NMDA antagonist effects in rats trained to discriminate lever-press counts.
Pharmacology, biochemistry, and behavior 2001;69(3-4):493-502.
2001: Anton Y Bespalov; Edwin E Zvartau; Patrick M Beardsley
Opioid-NMDA receptor interactions may clarify conditioned (associative) components of opioid analgesic tolerance.
Neuroscience and biobehavioral reviews 2001;25(4):343-53.
2001: Aloke Dutta; Xiang-Shu Fei; Patrick M Beardsley; Jennifer Newman; Maarten E A Reith
Structure-activity relationship studies of 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives and their N-analogues: evaluation of O-and N-analogues and their binding to monoamine transporters.
Journal of medicinal chemistry 2001;44(6):937-48.
2001: Patrick M Beardsley; Pierre Sokoloff; Robert L Balster; J C Schwartz
The D3R partial agonist, BP 897, attenuates the discriminative stimulus effects of cocaine and D-amphetamine and is not self-administered.
Behavioural pharmacology 2001;12(1):1-11.
2000: Anton Y Bespalov; Olga A Dravolina; Edwin E Zvartau; Patrick M Beardsley; Robert L Balster
Effects of NMDA receptor antagonists on cocaine-conditioned motor activity in rats.
European journal of pharmacology 2000;390(3):303-11.
2000: Anton Y Bespalov; Edwin E Zvartau; Robert L Balster; Patrick M Beardsley
Effects of N-methyl-D-aspartate receptor antagonists on reinstatement of cocaine-seeking behavior by priming injections of cocaine or exposures to cocaine-associated cues in rats.
Behavioural pharmacology 2000;11(1):37-44.
2000: Patrick M Beardsley; Billy R Martin
Effects of the cannabinoid CB(1) receptor antagonist, SR141716A, after Delta(9)-tetrahydrocannabinol withdrawal.
European journal of pharmacology 2000;387(1):47-53.
1999: Anton Y Bespalov; Robert L Balster; Patrick M Beardsley
N-Methyl-D-aspartate receptor antagonists and the development of tolerance to the discriminative stimulus effects of morphine in rats.
The Journal of pharmacology and experimental therapeutics 1999;290(1):20-7.
1999: Anton Y Bespalov; Mary E Tokarz; Scott Bowen; Robert L Balster; Patrick M Beardsley
Effects of test conditions on the outcome of place conditioning with morphine and naltrexone in mice.
Psychopharmacology 1999;141(2):118-22.
1998: Anton Y Bespalov; Patrick M Beardsley; Robert L Balster
Interactions between N-methyl-D-aspartate receptor antagonists and the discriminative stimulus effects of morphine in rats.
Pharmacology, biochemistry, and behavior 1998;60(2):507-17.
1998: charlie cook; F I Carroll; Patrick M Beardsley
Separation of the locomotor stimulant and discriminative stimulus effects of cocaine by its C-2 phenyl ester analog, RTI-15.
Drug and alcohol dependence 1998;50(2):123-8.
1997: Patrick M Beardsley; Louis S Harris
Evaluation of the discriminative stimulus and reinforcing effects of dihydroetorphine.
Drug and alcohol dependence 1997;48(2):77-84.
1993: Patrick M Beardsley; Robert L Balster
The effects of delay of reinforcement and dose on the self-administration of cocaine and procaine in rhesus monkeys.
Drug and alcohol dependence 1993;34(1):37-43.
1992: Patrick M Beardsley; Robert L Balster
The intravenous self-administration of antihistamines by rhesus monkeys.
Drug and alcohol dependence 1992;30(2):117-26.
1990: Patrick M Beardsley; B A Hayes; Robert L Balster
The self-administration of MK-801 can depend upon drug-reinforcement history, and its discriminative stimulus properties are phencyclidine-like in rhesus monkeys.
The Journal of pharmacology and experimental therapeutics 1990;252(3):953-9.
1989: Janet S Knisely; Patrick M Beardsley; Mario D Aceto; Robert L Balster; Louis S Harris
Assessment of the abuse potential of acetorphan, an enkephalinase inhibitor.
Drug and alcohol dependence 1989;23(2):143-51.
1988: Patrick M Beardsley; Robert L Balster
Evaluation of antagonists of the discriminative stimulus and response rate effects of phencyclidine.
The Journal of pharmacology and experimental therapeutics 1988;244(1):34-40.
1987: Billy R Martin; DR Compton; P J Little; T J Martin; Patrick M Beardsley
Pharmacological evaluation of agonistic and antagonistic activity of cannabinoids.
NIDA research monograph 1987;79():108-22.