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Tomi Mikkola

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Päivi Rahkola-Soisalo; Saara Vuorento; Olavi Ylikorkala; Tomi S Mikkola; Mervi Väisänen-Tommiska
Smoking is accompanied by a suppressed cervical nitric oxide release in women with high-risk human papillomavirus infection.
Päivi Rahkola-Soisalo; Hanna Savolainen-Peltonen; Mervi Väisänen-Tommiska; Olavi Ylikorkala; Ralf Butzow; Tomi S Mikkola
High-risk human papillomavirus-induced expression of endothelial and inducible nitric oxide synthase in human uterine cervix.
Pauliina Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Menopausal hot flashes and insulin resistance.

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All Publications

2013: Päivi Rahkola-Soisalo; Saara Vuorento; Olavi Ylikorkala; Tomi S Mikkola; Mervi Väisänen-Tommiska
Smoking is accompanied by a suppressed cervical nitric oxide release in women with high-risk human papillomavirus infection.
Acta obstetricia et gynecologica Scandinavica 2013;92(6):711-5.
2013: Päivi Rahkola-Soisalo; Hanna Savolainen-Peltonen; Mervi Väisänen-Tommiska; Olavi Ylikorkala; Ralf Butzow; Tomi S Mikkola
High-risk human papillomavirus-induced expression of endothelial and inducible nitric oxide synthase in human uterine cervix.
Annals of medicine 2013;45(1):79-84.
2012: Pauliina Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Menopausal hot flashes and insulin resistance.
Menopause (New York, N.Y.) 2012;19(10):1116-20.
2012: Feng Wang; Ursula Turpeinen; Veera Vihma; Kristiina Wähälä; Maija Badeau; Christian Fledelius; Esa Hämäläinen; Elina Ikonen; Matti Jauhiainen; Marjut Leidenius; Tomi S Mikkola; Hanna Savolainen-Peltonen; Matti J Tikkanen
Fatty acyl esterification and deesterification of 17β-estradiol in human breast subcutaneous adipose tissue.
The Journal of clinical endocrinology and metabolism 2012;97(9):3349-56.
2012: Riitta Luoto; Kirsi Mansikkamäki; Tomi S Mikkola; Jaana Moilanen; Katriina Ojala; Jani Raitanen; Eija Tomas; Reetta Heinonen; Clas-Håkan Nygård
Effect of aerobic training on hot flushes and quality of life--a randomized controlled trial.
Annals of medicine 2012;44(6):616-26.
2012: Tomi S Mikkola
Climacteric commentaries. Statin use and the risk for diabetes mellitus.
Climacteric : the journal of the International Menopause Society 2012;15(4):400.
2012: Kirsi Mansikkamäki; Tomi S Mikkola; Clas-Håkan Nygård; Jani Raitanen; Reetta Heinonen; Riitta Luoto
Sleep quality and aerobic training among menopausal women--a randomized controlled trial.
Maturitas 2012;72(4):339-45.
2012: Hanna Hautamäki; Petri Haapalahti; Päivi Piirilä; Anssi Sovijärvi; Pauliina Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Effect of hot flushes on cardiovascular autonomic responsiveness: a randomized controlled trial on hormone therapy.
Maturitas 2012;72(3):243-8.
2012: Jaana M Moilanen; Clas-Håkan Nygård; Jani A Raitanen; Eija I Tomas; Reetta H Heinonen; Tomi S Mikkola; Riitta Luoto
Effect of aerobic training on menopausal symptoms--a randomized controlled trial.
Menopause (New York, N.Y.) 2012;19(6):691-6.
2012: P Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Plasma nitrite/nitrate levels in women with postmenopausal hot flushes.
Climacteric : the journal of the International Menopause Society 2012;15(2):153-6.
2011: Pauliina Tuomikoski; Tomi S Mikkola; Olavi Ylikorkala
Hormone therapy and vasomotor symptoms.
Menopause (New York, N.Y.) 2011;18(12):1335.
2011: Päivi Rahkola; Mervi Väisänen-Tommiska; Olavi Ylikorkala; Eeva Auvinen; Eija Hiltunen-Back; Tomi S Mikkola
Cervical nitric oxide release in Chlamydia trachomatis and high-risk human papillomavirus infection.
Acta obstetricia et gynecologica Scandinavica 2011;90(9):961-5.
2011: Tomi S Mikkola
The hot flush--a determinant for vascular effects of estrogen?
Maturitas 2011;69(4):287-8.
2011: Päivi Rahkola; Mervi Väisänen-Tommiska; Pauliina Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Cervical nitric oxide release and persistence of high-risk human papillomavirus in women.
International journal of cancer. Journal international du cancer 2011;128(12):2933-7.
2011: Pauliina Tuomikoski; Olavi Ylikorkala; Tomi S Mikkola
Menopausal hot flushes and vascular health.
Annals of medicine 2011;43(4):283-91.
2011: Feng Wang; Anja Koskela; Esa Hämäläinen; Ursula Turpeinen; Hanna Savolainen-Peltonen; Tomi S Mikkola; Veera Vihma; Herman Adlercreutz; Matti J Tikkanen
Quantitative determination of dehydroepiandrosterone fatty acyl esters in human female adipose tissue and serum using mass spectrometric methods.
The Journal of steroid biochemistry and molecular biology 2011;124(3-5):93-8.
2011: Hanna Hautamäki; Päivi Piirilä; Petri Haapalahti; Pauliina Tuomikoski; Anssi R A Sovijärvi; Olavi Ylikorkala; Tomi S Mikkola
Cardiovascular autonomic responsiveness in postmenopausal women with and without hot flushes.
Maturitas 2011;68(4):368-73.
2010: P Tuomikoski; Tomi S Mikkola; Matti J Tikkanen; Olavi Ylikorkala
Hot flushes and biochemical markers for cardiovascular disease: a randomized trial on hormone therapy.
Climacteric : the journal of the International Menopause Society 2010;13(5):457-66.
2010: Pauliina Tuomikoski; Petri Haapalahti; Seppo Sarna; Olavi Ylikorkala; Tomi S Mikkola
Vasomotor hot flushes and 24-hour ambulatory blood pressure in normotensive women: A placebo-controlled trial on post-menopausal hormone therapy.
Annals of medicine 2010;42(5):334-43.
2010: Micheline C Deschênes; Denise Descovich; Michèle Moreau; Louis Granger; George A Kuchel; Tomi S Mikkola; Gordon H Fick; Sylvain Chemtob; Elvire Vaucher; Mark R Lesk
Postmenopausal hormone therapy increases retinal blood flow and protects the retinal nerve fiber layer.
Investigative ophthalmology & visual science 2010;51(5):2587-600.
2010: Pauliina Tuomikoski; Petri Haapalahti; Olavi Ylikorkala; Tomi S Mikkola
Vasomotor hot flushes and 24-hour ambulatory blood pressure in recently post-menopausal women.
Annals of medicine 2010;42(3):216-22.
2010: Hanna Hoikkala; Petri Haapalahti; Matti Viitasalo; Heikki Väänänen; Anssi R A Sovijärvi; Olavi Ylikorkala; Tomi S Mikkola
Association between vasomotor hot flashes and heart rate variability in recently postmenopausal women.
Menopause (New York, N.Y.) 2010;17(2):315-20.
2010: Pauliina Tuomikoski; Tomi S Mikkola; Esa Hämäläinen; Matti J Tikkanen; Ursula Turpeinen; Olavi Ylikorkala
Biochemical markers for cardiovascular disease in recently postmenopausal women with or without hot flashes.
Menopause (New York, N.Y.) 2010;17(1):145-51.
2009: Pauliina Tuomikoski; Pia Ebert; Per-Henrik Groop; Petri Haapalahti; Hanna Hautamäki; Mats Rönnback; Olavi Ylikorkala; Tomi S Mikkola
Effect of hot flushes on vascular function: a randomized controlled trial.
Obstetrics and gynecology 2009;114(4):777-85.
2009: Paivi Rahkola; Tomi S Mikkola; Olavi Ylikorkala; Mervi Vaisanen-Tommiska
Association between high risk papillomavirus DNA and nitric oxide release in the human uterine cervix.
Gynecologic oncology 2009;114(2):323-6.
2009: Pauliina Tuomikoski; Pia Ebert; Per-Henrik Groop; Petri Haapalahti; Hanna Hautamäki; Mats Rönnback; Olavi Ylikorkala; Tomi S Mikkola
Evidence for a role of hot flushes in vascular function in recently postmenopausal women.
Obstetrics and gynecology 2009;113(4):902-8.
2009: Tomi S Mikkola
Cardiovascular risk assessment in postmenopausal women: the role of the gynecologist.
Climacteric : the journal of the International Menopause Society 2009;12 Suppl 1():58-61.
2009: Paivi Rahkola; Tomi S Mikkola; Pekka Nieminen; Olavi Ylikorkala; Mervi Vaisanen-Tommiska
Abnormal cervical cytology is associated with increased nitric oxide release in the uterine cervix.
Acta obstetricia et gynecologica Scandinavica 2009;88(4):417-21.
2008: R Törmälä; S Appt; Thomas B Clarkson; A O Mueck; H Seeger; Tomi S Mikkola; Olavi Ylikorkala
Impact of soy supplementation on sex steroids and vascular inflammation markers in postmenopausal women using tibolone: role of equol production capability.
Climacteric : the journal of the International Menopause Society 2008;11(5):409-15.
2008: Susan E Appt; Riina Törmälä; Adrian Franke; Tomi S Mikkola; Matti J Tikkanen; Olavi Ylikorkala; Thomas B Clarkson
Soy-tibolone combination - effect on lipids in postmenopausal monkeys and women.
Maturitas 2008;60(3-4):216-22.
2008: Riina Törmälä; Susan Appt; Thomas B Clarkson; Per-Henrik Groop; Mats Rönnback; Olavi Ylikorkala; Tomi S Mikkola
Equol production capability is associated with favorable vascular function in postmenopausal women using tibolone; no effect with soy supplementation.
Atherosclerosis 2008;198(1):174-8.
2008: Pauliina Tuomikoski; Kristiina Aittomäki; Tomi S Mikkola; Anne Ropponen; Olavi Ylikorkala
Effect of oral and transdermal hormone therapy on hyaluronic acid in women with and without a history of intrahepatic cholestasis of pregnancy.
American journal of obstetrics and gynecology 2008;198(4):375.e1-5.
2007: R M Törmälä; Susan E Appt; Thomas B Clarkson; Matti J Tikkanen; Olavi Ylikorkala; Tomi S Mikkola
Individual differences in equol production capability modulate blood pressure in tibolone-treated postmenopausal women: lack of effect of soy supplementation.
Climacteric : the journal of the International Menopause Society 2007;10(6):471-9.
2007: Maija Badeau; Veera Vihma; Tomi S Mikkola; Aila Tiitinen; Matti J Tikkanen
Estradiol fatty acid esters in adipose tissue and serum of pregnant and pre- and postmenopausal women.
The Journal of clinical endocrinology and metabolism 2007;92(11):4327-31.
2007: Robert Badeau; Matti Jauhiainen; Jari Metso; Eini Nikander; Matti J Tikkanen; Olavi Ylikorkala; Tomi S Mikkola
Effect of isolated isoflavone supplementation on ABCA1-dependent cholesterol efflux potential in postmenopausal women.
Menopause (New York, N.Y.) 2007;14(2):293-9.
2006: Mervi Väisänen-Tommiska; Ralf Butzow; Olavi Ylikorkala; Tomi S Mikkola
Mifepristone-induced nitric oxide release and expression of nitric oxide synthases in the human cervix during early pregnancy.
Human reproduction (Oxford, England) 2006;21(8):2180-4.
2006: Markku Kupari; Tomi S Mikkola; Heikki Turto; Jyri Lommi; Olavi Ylikorkala
Vasoactive intestinal peptide--release from the heart and response in heart failure due to left ventricular pressure overload.
European journal of heart failure 2006;8(4):361-5.
2006: Riina M Törmälä; Eini Nikander; Aila Tiitinen; Mervi Väisänen-Tommiska; Olavi Ylikorkala; Tomi S Mikkola
Serum cholesterol efflux potential in postmenopausal women treated with isolated isoflavones.
Menopause (New York, N.Y.) 2006;13(1):96-101.
2006: Tomi S Mikkola; Thomas B Clarkson
Coronary heart disease and postmenopausal hormone therapy: conundrum explained by timing?
Journal of women's health (2002) 2006;15(1):51-3.
2005: Maija Badeau; Matti J Tikkanen; Susan E Appt; Herman Adlercreutz; Thomas B Clarkson; Antti Hoikkala; Kristiina Wähälä; Tomi S Mikkola
Determination of plasma genistein fatty acid esters following administration of genistein or genistein 4'7-O-dioleate in monkeys.
Biochimica et biophysica acta 2005;1738(1-3):115-20.
2005: Mervi Väisänen-Tommiska; Tomi S Mikkola; Olavi Ylikorkala
Misoprostol induces cervical nitric oxide release in pregnant, but not in nonpregnant, women.
American journal of obstetrics and gynecology 2005;193(3 Pt 1):790-6.
2005: Markku Kupari; Tomi S Mikkola; Heikki Turto; Jyri Lommi
Is the pregnancy hormone relaxin an important player in human heart failure?
European journal of heart failure 2005;7(2):195-8.
2005: Tomi S Mikkola; Olavi Ylikorkala
Hormone therapy and cardiovascular disease--still much to be learnt.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2005;20(2):116-20.
2004: Mervi Väisänen-Tommiska; Tomi S Mikkola; Olavi Ylikorkala
Increased release of cervical nitric oxide in spontaneous abortion before clinical symptoms: a possible mechanism for preabortal cervical ripening.
The Journal of clinical endocrinology and metabolism 2004;89(11):5622-6.
2004: Tomi S Mikkola; Thomas B Clarkson; Morris Notelovitz
Postmenopausal hormone therapy before and after the women's health initiative study: what consequences?
Annals of medicine 2004;36(6):402-13.
2003: Tomi S Mikkola; Mary S Anthony; Thomas B Clarkson; Richard W St Clair
Serum cholesterol efflux potential is an independent predictor of coronary artery atherosclerosis.
Atherosclerosis 2003;170(1):31-8.
2002: Thomas B Clarkson; Mary S Anthony; Tomi S Mikkola; Richard W St Clair
Comparison of tibolone and conjugated equine estrogens effects on carotid artery atherosclerosis of postmenopausal monkeys.
Stroke; a journal of cerebral circulation 2002;33(11):2700-3.
2002: Tomi S Mikkola; Richard W St Clair
Estradiol reduces basal and cytokine induced monocyte adhesion to endothelial cells.
Maturitas 2002;41(4):313-9.
2002: Tomi S Mikkola; Mary S Anthony; Thomas B Clarkson; Richard W St Clair
Serum cholesterol efflux potential in postmenopausal monkeys treated with tibolone or conjugated estrogens.
Metabolism: clinical and experimental 2002;51(4):523-30.
2002: Tomi S Mikkola; Thomas B Clarkson
Estrogen replacement therapy, atherosclerosis, and vascular function.
Cardiovascular research 2002;53(3):605-19.
2000: Tomi S Mikkola; Lasse Viinikka; Olavi Ylikorkala
Administration of transdermal estrogen without progestin increases the capacity of plasma and serum to stimulate prostacyclin production in human vascular endothelial cells.
Fertility and sterility 2000;73(1):72-4.
1999: Heikki Summala; Helinä Häkkänen; Tomi S Mikkola; Jari Sinkkonen
Task effects on fatigue symptoms in overnight driving.
Ergonomics 1999;42(6):798-806.
1998: Tomi S Mikkola; Lasse Viinikka; Olavi Ylikorkala
Estrogen and postmenopausal estrogen/progestin therapy: effect on endothelium-dependent prostacyclin, nitric oxide and endothelin-1 production.
European journal of obstetrics, gynecology, and reproductive biology 1998;79(1):75-82.
1998: Varpu Ranta; Tomi S Mikkola; Olavi Ylikorkala; Lasse Viinikka; Arto Orpana
Reduced viability of human vascular endothelial cells cultured on Matrigel.
Journal of cellular physiology 1998;176(1):92-8.
1997: Varpu Ranta; Arto Orpana; Tomi S Mikkola; Olavi Ylikorkala; Lasse Viinikka
Culturing of human vascular endothelial cells strongly affects their endothelin-1 and prostacyclin production.
Molecular and cellular biochemistry 1997;177(1-2):251-5.
1997: Arto Orpana; Varpu Ranta; Tomi S Mikkola; Lasse Viinikka; Olavi Ylikorkala
Inducible nitric oxide and prostacyclin productions are differently controlled by extracellular matrix and cell density in human vascular endothelial cells.
Journal of cellular biochemistry 1997;64(4):538-46.
1996: Tomi S Mikkola; Varpu Ranta; Arto Orpana; Olavi Ylikorkala; Lasse Viinikka
Effect of physiological concentrations of estradiol on PGI2 and NO in endothelial cells.
Maturitas 1996;25(2):141-7.
1996: Tomi S Mikkola; Varpu Ranta; Arto Orpana; Lasse Viinikka; Olavi Ylikorkala
Hormone replacement therapy modifies the capacity of plasma and serum to regulate prostacyclin and endothelin-1 production in human vascular endothelial cells.
Fertility and sterility 1996;66(3):389-93.
1996: P Turunen; Tomi S Mikkola; Olavi Ylikorkala; Lasse Viinikka
Hirudin stimulates prostacyclin but not endothelin-1 production in cultured human vascular endothelial cells.
Thrombosis research 1996;81(6):635-40.
1995: Tomi S Mikkola; P Turunen; Kristiina Avela; Arto Orpana; Lasse Viinikka; Olavi Ylikorkala
17 beta-estradiol stimulates prostacyclin, but not endothelin-1, production in human vascular endothelial cells.
The Journal of clinical endocrinology and metabolism 1995;80(6):1832-6.
1994: Heikki Summala; Tomi S Mikkola
Fatal accidents among car and truck drivers: effects of fatigue, age, and alcohol consumption.
Human factors 1994;36(2):315-26.
1993: Tomi S Mikkola; A Ristimäki; Lasse Viinikka; Olavi Ylikorkala
Human serum, plasma, and platelets stimulate prostacyclin and endothelin-1 synthesis in human vascular endothelial cells.
Life sciences 1993;53(3):283-9.