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Mario Milani

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Yannick Ouellet; Richard Daigle; Patrick Lagüe; David Dantsker; Mario Milani; Martino Bolognesi; Joel Mitchel Friedman; Michel Guertin
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water.
Alessandra Pesce; Mario Milani; Marco Nardini; Martino Bolognesi
Mapping heme-ligand tunnels in group I truncated(2/2) hemoglobins.
Hugues Ouellet; Mario Milani; Marie Labarre; Martino Bolognesi; Manon Couture; Michel Guertin
The roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis truncated hemoglobin O in ligand binding and on the heme distal site architecture.

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All Publications

2008: Yannick Ouellet; Richard Daigle; Patrick Lagüe; David Dantsker; Mario Milani; Martino Bolognesi; Joel Mitchel Friedman; Michel Guertin
Ligand binding to truncated hemoglobin N from Mycobacterium tuberculosis is strongly modulated by the interplay between the distal heme pocket residues and internal water.
The Journal of biological chemistry 2008;283(40):27270-8.
2008: Alessandra Pesce; Mario Milani; Marco Nardini; Martino Bolognesi
Mapping heme-ligand tunnels in group I truncated(2/2) hemoglobins.
Methods in enzymology 2008;436():303-15.
2007: Hugues Ouellet; Mario Milani; Marie Labarre; Martino Bolognesi; Manon Couture; Michel Guertin
The roles of Tyr(CD1) and Trp(G8) in Mycobacterium tuberculosis truncated hemoglobin O in ligand binding and on the heme distal site architecture.
Biochemistry 2007;46(41):11440-50.
2007: Alessandra Pesce; Marco Nardini; Mario Milani; Martino Bolognesi
Protein structure in the truncated (2/2) hemoglobin family.
IUBMB life 2007;59(8-9):535-41.
2006: Yannick Ouellet; Mario Milani; Manon Couture; Martino Bolognesi; Michel Guertin
Ligand interactions in the distal heme pocket of Mycobacterium tuberculosis truncated hemoglobin N: roles of TyrB10 and GlnE11 residues.
Biochemistry 2006;45(29):8770-81.
2005: Mario Milani; Alessandra Pesce; Marco Nardini; Hugues Ouellet; Yannick Ouellet; Sylvia Dewilde; Alessio Bocedi; Paolo Ascenzi; Michel Guertin; Luc Moens; Joel Mitchel Friedman; Jonathan B Wittenberg; Martino Bolognesi
Structural bases for heme binding and diatomic ligand recognition in truncated hemoglobins.
Journal of inorganic biochemistry 2005;99(1):97-109.
2004: David Dantsker; Uri Samuni; Yannick Ouellet; Beatrice A Wittenberg; Jonathan B Wittenberg; Mario Milani; Martino Bolognesi; Michel Guertin; Joel Mitchel Friedman
Viscosity-dependent relaxation significantly modulates the kinetics of CO recombination in the truncated hemoglobin TrHbN from Mycobacterium tuberculosis.
The Journal of biological chemistry 2004;279(37):38844-53.
2004: Mario Milani; Alessandra Pesce; Yannick Ouellet; Sylvia Dewilde; Joel Mitchel Friedman; Paolo Ascenzi; Michel Guertin; Martino Bolognesi
Heme-ligand tunneling in group I truncated hemoglobins.
The Journal of biological chemistry 2004;279(20):21520-5.
2004: Mario Milani; Yannick Ouellet; Hugues Ouellet; Michel Guertin; Alberto Boffi; Giovanni Antonini; Alessio Bocedi; Marco Mattu; Martino Bolognesi; Paolo Ascenzi
Cyanide binding to truncated hemoglobins: a crystallographic and kinetic study.
Biochemistry 2004;43(18):5213-21.
2003: Mario Milani; Alessandra Pesce; Hugues Ouellet; Michel Guertin; Martino Bolognesi
Truncated hemoglobins and nitric oxide action.
IUBMB life 2003;55(10-11):623-7.
2003: Mario Milani; Pierre-Yves Savard; Hugues Ouellet; Paolo Ascenzi; Michel Guertin; Martino Bolognesi
A TyrCD1/TrpG8 hydrogen bond network and a TyrB10TyrCD1 covalent link shape the heme distal site of Mycobacterium tuberculosis hemoglobin O.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5766-71.
2002: Mario Milani; Alessandra Pesce; Sylvia Dewilde; Paolo Ascenzi; Luc Moens; Martino Bolognesi
Structural plasticity in the eight-helix fold of a trematode haemoglobin.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 4):719-22.
2001: Mario Milani; Laura Andolfi; Salvatore Cannistraro; Martin Ph Verbeet; Martino Bolognesi
The 1.6 A resolution crystal structure of a mutant plastocyanin bearing a 21-25 engineered disulfide bridge.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 11):1735-8.
2001: Mario Milani; Alessandra Pesce; Yannick Ouellet; Paolo Ascenzi; Michel Guertin; Martino Bolognesi
Mycobacterium tuberculosis hemoglobin N displays a protein tunnel suited for O2 diffusion to the heme.
The EMBO journal 2001;20(15):3902-9.
2001: Alessandra Pesce; Sylvia Dewilde; Laurent Kiger; Mario Milani; Paolo Ascenzi; Michael C Marden; Marie-Louise Van Hauwaert; J Vanfleteren; Luc Moens; Martino Bolognesi
Very high resolution structure of a trematode hemoglobin displaying a TyrB10-TyrE7 heme distal residue pair and high oxygen affinity.
Journal of molecular biology 2001;309(5):1153-64.