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John Millar

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John S Millar
Novel benefits of peroxisome proliferator-activated receptors on cardiovascular risk.
Esther M M Ooi; Helen Rasmussen; Francine K Welty; P Hugh R Barrett; Margaret R Diffenderfer; Stefania Lamon-Fava; Alice H Lichtenstein; John S Millar; Ernst J Schaefer
Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects.
Margaret R Diffenderfer; Gregory G Dolnikowski; John S Millar; Chorthip Nartsupha; Daniel J Rader; P Hugh R Barrett; Margaret E Brousseau; Peter M Schaefer; Megan L Wolfe; Ernst J Schaefer
Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism.

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All Publications

2013: John S Millar
Novel benefits of peroxisome proliferator-activated receptors on cardiovascular risk.
Current opinion in lipidology 2013;24(3):233-8.
2012: Esther M M Ooi; Helen Rasmussen; Francine K Welty; P Hugh R Barrett; Margaret R Diffenderfer; Stefania Lamon-Fava; Alice H Lichtenstein; John S Millar; Ernst J Schaefer
Effects of Therapeutic Lifestyle Change diets high and low in dietary fish-derived FAs on lipoprotein metabolism in middle-aged and elderly subjects.
Journal of lipid research 2012;53(9):1958-67.
2012: Margaret R Diffenderfer; Gregory G Dolnikowski; John S Millar; Chorthip Nartsupha; Daniel J Rader; P Hugh R Barrett; Margaret E Brousseau; Peter M Schaefer; Megan L Wolfe; Ernst J Schaefer
Effects of CETP inhibition on triglyceride-rich lipoprotein composition and apoB-48 metabolism.
Journal of lipid research 2012;53(6):1190-9.
2011: Sue-Anne Toh; John S Millar; Jeffrey T Billheimer; Ilia V Fuki; Snehal U Naik; Colin H Macphee; Max Walker; Daniel J Rader
PPARγ activation redirects macrophage cholesterol from fecal excretion to adipose tissue uptake in mice via SR-BI.
Biochemical pharmacology 2011;81(7):934-41.
2011: John S Millar; Katsunori Ikewaki; LeAnne T Bloedon; Megan L Wolfe; Philippe Szapary; Daniel J Rader
Effect of rosiglitazone on HDL metabolism in subjects with metabolic syndrome and low HDL.
Journal of lipid research 2011;52(1):136-42.
2010: Xiaoyu Li; John S Millar; Nicholas Brownell; Francois BRIAND; Daniel J Rader
Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.
Biochemical pharmacology 2010;80(9):1450-7.
2010: John S Millar; Bonnie Ky; Megan L Wolfe; Leticia Pruscino; Amanda Baer; Daniel J Rader
Short-term treatment with high-dose atorvastatin reduces LDL cholesterol but shows no anti-inflammatory effects in normolipidemic subjects with normal CRP levels.
Clinical and translational science 2010;3(4):140-6.
2010: Ashish S Shah; Daniel J Rader; John S Millar
The effect of PPAR-alpha agonism on apolipoprotein metabolism in humans.
Atherosclerosis 2010;210(1):35-40.
2010: Marina Cuchel; Sissel Lund-Katz; Margarita de la Llera-Moya; John S Millar; David Chang; Ilia V Fuki; George H Rothblat; Michael C Phillips; Daniel J Rader
Pathways by which reconstituted high-density lipoprotein mobilizes free cholesterol from whole body and from macrophages.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(3):526-32.
2009: Margaret E Brousseau; John S Millar; Margaret R Diffenderfer; Chorthip Nartsupha; Bela F Asztalos; Megan L Wolfe; James P Mancuso; Andres G Digenio; Daniel J Rader; Ernst J Schaefer
Effects of cholesteryl ester transfer protein inhibition on apolipoprotein A-II-containing HDL subspecies and apolipoprotein A-II metabolism.
Journal of lipid research 2009;50(7):1456-62.
2009: Junichiro Tohyama; Jeffrey T Billheimer; Ilia V Fuki; George H Rothblat; Daniel J Rader; John S Millar
Effects of nevirapine and efavirenz on HDL cholesterol levels and reverse cholesterol transport in mice.
Atherosclerosis 2009;204(2):418-23.
2009: Francois BRIAND; Snehal U Naik; Ilia Fuki; John S Millar; Colin H Macphee; Max Walker; Jeffrey Billheimer; George Rothblat; Daniel J Rader
Both the peroxisome proliferator-activated receptor delta agonist, GW0742, and ezetimibe promote reverse cholesterol transport in mice by reducing intestinal reabsorption of HDL-derived cholesterol.
Clinical and translational science 2009;2(2):127-33.
2009: Ioannis M Stylianou; Karen L Svenson; Sara K VanOrman; Yanina Langle; John S Millar; Beverly Paigen; Daniel J Rader
Novel ENU-induced point mutation in scavenger receptor class B, member 1, results in liver specific loss of SCARB1 protein.
PloS one 2009;4(8):e6521.
2008: Ying Liu; John S Millar; Debra Cromley; Mark Graham; Rosanne Crooke; Jeffrey T Billheimer; Daniel J Rader
Knockdown of acyl-CoA:diacylglycerol acyltransferase 2 with antisense oligonucleotide reduces VLDL TG and ApoB secretion in mice.
Biochimica et biophysica acta 2008;1781(3):97-104.
2008: John S Millar; Margaret E Brousseau; Margaret R Diffenderfer; Hugh Barrett; Francine K Welty; Jeffrey S Cohn; Aisha Wilson; Megan L Wolfe; Chorthip Nartsupha; Peter M Schaefer; Andres G Digenio; James P Mancuso; Gregory G Dolnikowski; Ernst Schaefer; Daniel J Rader
Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on VLDL apolipoprotein E metabolism.
Journal of lipid research 2008;49(3):543-9.
2007: Weijun Jin; Xun Wang; John S Millar; Thomas Quertermous; George H Rothblat; Jane M Glick; Daniel J Rader
Hepatic proprotein convertases modulate HDL metabolism.
Cell metabolism 2007;6(2):129-36.
2007: Marina Cuchel; LeAnne T Bloedon; Philippe Szapary; Daniel M Kolansky; Megan L Wolfe; Antoine Sarkis; John S Millar; Katsunori Ikewaki; Evan S Siegelman; Richard E Gregg; Daniel J Rader
Inhibition of microsomal triglyceride transfer protein in familial hypercholesterolemia.
The New England journal of medicine 2007;356(2):148-56.
2006: Uli C Broedl; Weijun Jin; Ilia V Fuki; John S Millar; Daniel J Rader
Endothelial lipase is less effective at influencing HDL metabolism in vivo in mice expressing apoA-II.
Journal of lipid research 2006;47(10):2191-7.
2006: John S Millar; Scot J Stone; Uwe J F Tietge; Bryan Tow; Jeffrey T Billheimer; Jinny S Wong; Robert L Hamilton; Robert V Farese; Daniel J Rader
Short-term overexpression of DGAT1 or DGAT2 increases hepatic triglyceride but not VLDL triglyceride or apoB production.
Journal of lipid research 2006;47(10):2297-305.
2006: John S Millar; Margaret E Brousseau; Margaret R Diffenderfer; Hugh Barrett; Francine K Welty; Aisha Faruqi; Megan L Wolfe; Chorthip Nartsupha; Andres G Digenio; James P Mancuso; Gregory G Dolnikowski; Ernst Schaefer; Daniel J Rader
Effects of the cholesteryl ester transfer protein inhibitor torcetrapib on apolipoprotein B100 metabolism in humans.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(6):1350-6.
2005: William Cain; John S Millar; Adam S Himebauch; Uwe J F Tietge; Cyrille Maugeais; David Usher; Daniel J Rader
Lipoprotein [a] is cleared from the plasma primarily by the liver in a process mediated by apolipoprotein [a].
Journal of lipid research 2005;46(12):2681-91.
2005: Ryan E Moore; Mohamad Navab; John S Millar; Francesca Zimetti; Susan Hama; George H Rothblat; Daniel J Rader
Increased atherosclerosis in mice lacking apolipoprotein A-I attributable to both impaired reverse cholesterol transport and increased inflammation.
Circulation research 2005;97(8):763-71.
2005: John S Millar; Debra Cromley; Mary G McCoy; Daniel J Rader; Jeffrey T Billheimer
Determining hepatic triglyceride production in mice: comparison of poloxamer 407 with Triton WR-1339.
Journal of lipid research 2005;46(9):2023-8.
2005: Margaret E Brousseau; Margaret R Diffenderfer; John S Millar; Chorthip Nartsupha; Bela F Asztalos; Francine K Welty; Megan L Wolfe; Mats Rudling; Ingemar Björkhem; Bo Angelin; James P Mancuso; Andres G Digenio; Daniel J Rader; Ernst Schaefer
Effects of cholesteryl ester transfer protein inhibition on high-density lipoprotein subspecies, apolipoprotein A-I metabolism, and fecal sterol excretion.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(5):1057-64.
2005: Jennifer L Jenner; Leo J Seman; John S Millar; Stefania Lamon-Fava; Francine K Welty; Gregory G Dolnikowski; Santica M Marcovina; Alice H Lichtenstein; Hugh Barrett; Carl deLuca; Ernst Schaefer
The metabolism of apolipoproteins (a) and B-100 within plasma lipoprotein (a) in human beings.
Metabolism: clinical and experimental 2005;54(3):361-9.
2005: John S Millar; Cyrille Maugeais; Katsunori Ikewaki; Daniel M Kolansky; Hugh Barrett; Elaine C Budreck; Raymond C Boston; Norio Tada; Seibu Mochizuki; Joep C Defesche; James M Wilson; Daniel J Rader
Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(3):560-5.
2004: Uli C Broedl; Cyrille Maugeais; John S Millar; Weijun Jin; Ryan E Moore; Ilia V Fuki; Dawn Marchadier; Jane M Glick; Daniel J Rader
Endothelial lipase promotes the catabolism of ApoB-containing lipoproteins.
Circulation research 2004;94(12):1554-61.
2003: Ryan E Moore; Masa-aki Kawashiri; Ken Kitajima; Anthony Secreto; John S Millar; Domenico Pratico'; Daniel J Rader
Apolipoprotein A-I deficiency results in markedly increased atherosclerosis in mice lacking the LDL receptor.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(10):1914-20.
2003: Ilia V Fuki; Nadine Blanchard; Weijun Jin; Dawn Marchadier; John S Millar; Jane M Glick; Daniel J Rader
Endogenously produced endothelial lipase enhances binding and cellular processing of plasma lipoproteins via heparan sulfate proteoglycan-mediated pathway.
The Journal of biological chemistry 2003;278(36):34331-8.
2003: Weijun Jin; John S Millar; Uli C Broedl; Jane M Glick; Daniel J Rader
Inhibition of endothelial lipase causes increased HDL cholesterol levels in vivo.
The Journal of clinical investigation 2003;111(3):357-62.
2002: John S Millar; Cyrille Maugeais; Ilia V Fuki; Daniel J Rader
Normal production rate of apolipoprotein B in LDL receptor-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):989-94.
2001: John S Millar; Alice H Lichtenstein; Jose Ordovas; Gregory G Dolnikowski; Ernst Schaefer
Human triglyceride-rich lipoprotein apo E kinetics and its relationship to LDL apo B-100 metabolism.
Atherosclerosis 2001;155(2):477-85.
2001: John S Millar
The sialylation of plasma lipoproteins.
Atherosclerosis 2001;154(1):1-13.
1998: John S Millar; Alice H Lichtenstein; Gregory G Dolnikowski; Jose Ordovas; Ernst Schaefer
Proposal of a multicompartmental model for use in the study of apolipoprotein E metabolism.
Metabolism: clinical and experimental 1998;47(8):922-8.
1997: Marina Cuchel; Ernst Schaefer; John S Millar; P J Jones; Gregory G Dolnikowski; C Vergani; Alice H Lichtenstein
Lovastatin decreases de novo cholesterol synthesis and LDL Apo B-100 production rates in combined-hyperlipidemic males.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(10):1910-7.
1995: John S Millar; Alice H Lichtenstein; M Cuchel; Gregory G Dolnikowski; D L Hachey; J S Cohn; Ernst Schaefer
Impact of age on the metabolism of VLDL, IDL, and LDL apolipoprotein B-100 in men.
Journal of lipid research 1995;36(6):1155-67.
1993: J S Cohn; Elizabeth Johnson; John S Millar; S D Cohn; R W Milne; Y L Marcel; Robert M Russell; Ernst Schaefer
Contribution of apoB-48 and apoB-100 triglyceride-rich lipoproteins (TRL) to postprandial increases in the plasma concentration of TRL triglycerides and retinyl esters.
Journal of lipid research 1993;34(12):2033-40.
1992: Alice H Lichtenstein; D L Hachey; John S Millar; J L Jenner; L Booth; Jose Ordovas; Ernst Schaefer
Measurement of human apolipoprotein B-48 and B-100 kinetics in triglyceride-rich lipoproteins using [5,5,5-2H3]leucine.
Journal of lipid research 1992;33(6):907-14.
1990: Alice H Lichtenstein; J S Cohn; D L Hachey; John S Millar; Jose Ordovas; Ernst Schaefer
Comparison of deuterated leucine, valine, and lysine in the measurement of human apolipoprotein A-I and B-100 kinetics.
Journal of lipid research 1990;31(9):1693-701.
1990: J S Cohn; David A Wagner; S D Cohn; John S Millar; Ernst Schaefer
Measurement of very low density and low density lipoprotein apolipoprotein (Apo) B-100 and high density lipoprotein Apo A-I production in human subjects using deuterated leucine. Effect of fasting and feeding.
The Journal of clinical investigation 1990;85(3):804-11.