David Miller

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Reichel Valeska; Miller David S; Fricker Gert
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.
Hartz Anika M S; Bauer Björn; Block Michelle L; Hong Jau-Shyong; Miller David S
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier.
Miller David S; Bauer Björn; Hartz Anika M S
Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy.

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All Publications

2008: Reichel Valeska; Miller David S; Fricker Gert
Texas Red transport across rat and dogfish shark (Squalus acanthias) choroid plexus.
American journal of physiology. Regulatory, integrative and comparative physiology 2008;295(4):R1311-9.
2008: Hartz Anika M S; Bauer Björn; Block Michelle L; Hong Jau-Shyong; Miller David S
Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(8):2723-33.
2008: Miller David S; Bauer Björn; Hartz Anika M S
Modulation of P-glycoprotein at the blood-brain barrier: opportunities to improve central nervous system pharmacotherapy.
Pharmacological reviews 2008;60(2):196-209.
2008: Bauer Björn; Hartz Anika M S; Lucking Jonathan R; Yang Xiaodong; Pollack Gary M; Miller David S
Coordinated nuclear receptor regulation of the efflux transporter, Mrp2, and the phase-II metabolizing enzyme, GSTpi, at the blood-brain barrier.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(6):1222-34.
2008: Bow Daniel A J; Perry Jennifer L; Miller David S; Pritchard John B; Brouwer Kim L R
Localization of P-gp (Abcb1) and Mrp2 (Abcc2) in freshly isolated rat hepatocytes.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(1):198-202.
2007: Reichel Valeska; Masereeuw Rosalinde; van den Heuvel Jeroen J M W; Miller David S; Fricker Gert
Transport of a fluorescent cAMP analog in teleost proximal tubules.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;293(6):R2382-9.
2007: Pei Zhong; Pang Hao; Qian Li; Yang Sufen; Wang Tonggauang; Zhang Wei; Wu Xeufei; Dallas Shannon; Wilson Belinda; Reece Jeffrey M; Miller David S; Hong Jau-Shyong; Block Michelle L
MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity.
Glia 2007;55(13):1362-73.
2007: Zhang Wei; Dallas Shannon; Zhang Dan; Guo Jian-Ping; Pang Hao; Wilson Belinda; Miller David S; Chen Biao; Zhang Wanqin; McGeer Patrick L; Hong Jau-Shyong; Zhang Jing
Microglial PHOX and Mac-1 are essential to the enhanced dopaminergic neurodegeneration elicited by A30P and A53T mutant alpha-synuclein.
Glia 2007;55(11):1178-88.
2007: Wielgus Albert R; Chignell Colin F; Miller David S; Van Houten Ben; Meyer Joel; Hu Dan-Ning; Roberts Joan E
Phototoxicity in human retinal pigment epithelial cells promoted by hypericin, a component of St. John's wort.
Photochemistry and photobiology 2007;83(3):706-13.
2007: Miller David S; Shaw Joseph R; Stanton Caitlin R; Barnaby Roxanna; Karlson Katherine H; Hamilton Joshua W; Stanton Bruce A
MRP2 and acquired tolerance to inorganic arsenic in the kidney of killifish (Fundulus heteroclitus).
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(1):103-10.
2007: Bauer Björn; Hartz Anika M S; Miller David S
Tumor necrosis factor alpha and endothelin-1 increase P-glycoprotein expression and transport activity at the blood-brain barrier.
Molecular pharmacology 2007;71(3):667-75.
2006: Aslamkhan Amy G; Thompson Deborah M; Perry Jennifer L; Bleasby Kelly; Wolff Natascha A; Barros Scott; Miller David S; Pritchard John B
The flounder organic anion transporter fOat has sequence, function, and substrate specificity similarity to both mammalian Oat1 and Oat3.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(6):R1773-80.
2006: Bauer Björn; Yang Xiaodong; Hartz Anika M S; Olson Emily R; Zhao Rong; Kalvass J Cory; Pollack Gary M; Miller David S
In vivo activation of human pregnane X receptor tightens the blood-brain barrier to methadone through P-glycoprotein up-regulation.
Molecular pharmacology 2006;70(4):1212-9.
2006: Baehr Carsten H; Fricker Gert; Miller David S
Fluorescein-methotrexate transport in dogfish shark (Squalus acanthias) choroid plexus.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;291(2):R464-72.
2006: Dallas Shannon; Miller David S; Bendayan Reina
Multidrug resistance-associated proteins: expression and function in the central nervous system.
Pharmacological reviews 2006;58(2):140-61.
2006: Wang Tongguang; Zhang Wei; Pei Zhong; Block Michelle; Wilson Belinda; Reece Jeffrey M; Miller David S; Hong Jau-Shyong
Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(7):906-15.
2006: Hartz Anika M S; Bauer Björn; Fricker Gert; Miller David S
Rapid modulation of P-glycoprotein-mediated transport at the blood-brain barrier by tumor necrosis factor-alpha and lipopolysaccharide.
Molecular pharmacology 2006;69(2):462-70.
2005: Notenboom Sylvia; Miller David S; Kuik Leon H; Smits Paul; Russel Frans G M; Masereeuw Rosalinde
Short-term exposure of renal proximal tubules to gentamicin increases long-term multidrug resistance protein 2 (Abcc2) transport function and reduces nephrotoxicant sensitivity.
The Journal of pharmacology and experimental therapeutics 2005;315(2):912-20.
2005: Lowes Simon; Sykes Destiny; Breen Christopher M; Ragone Leigh J; Miller David S
Multiple components of 2,4-dichlorophenoxyacetic acid uptake by rat choroid plexus.
The Journal of pharmacology and experimental therapeutics 2005;315(1):136-43.
2005: Wang Tongguang; Pei Zhong; Zhang Wei; Liu Bin; Langenbach Robert; Lee Christopher; Wilson Belinda; Reece Jeffrey M; Miller David S; Hong Jau-Shyong
MPP+-induced COX-2 activation and subsequent dopaminergic neurodegeneration.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(9):1134-6.
2005: Pritchard John B; Miller David S
Expression systems for cloned xenobiotic transporters.
Toxicology and applied pharmacology 2005;204(3):256-62.
2005: Zhang Wei; Wang Tongguang; Pei Zhong; Miller David S; Wu Xuefei; Block Michelle L; Wilson Belinda; Zhang Wanqin; Zhou Yong; Hong Jau-Shyong; Zhang Jing
Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):533-42.
2005: Bauer Björn; Hartz Anika M S; Fricker Gert; Miller David S
Modulation of p-glycoprotein transport function at the blood-brain barrier.
Experimental biology and medicine (Maywood, N.J.) 2005;230(2):118-27.
2004: He Yu-Ying; Chignell Colin F; Miller David S; Andley Usha P; Roberts Joan E
Phototoxicity in human lens epithelial cells promoted by St. John's Wort.
Photochemistry and photobiology 2004;80(3):583-6.
2004: Miller David S
Confocal imaging of xenobiotic transport across the choroid plexus.
Advanced drug delivery reviews 2004;56(12):1811-24.
2004: Bauer Björn; Hartz Anika M S; Fricker Gert; Miller David S
Pregnane X receptor up-regulation of P-glycoprotein expression and transport function at the blood-brain barrier.
Molecular pharmacology 2004;66(3):413-9.
2004: Hartz Anika M S; Bauer Björn; Fricker Gert; Miller David S
Rapid regulation of P-glycoprotein at the blood-brain barrier by endothelin-1.
Molecular pharmacology 2004;66(3):387-94.
2004: Breen Christopher M; Sykes Destiny B; Baehr Carsten; Fricker Gert; Miller David S
Fluorescein-methotrexate transport in rat choroid plexus analyzed using confocal microscopy.
American journal of physiology. Renal physiology 2004;287(3):F562-9.
2004: Notenboom Sylvia; Miller David S; Smits P; Russel Frans G M; Masereeuw Rosalinde
Involvement of guanylyl cyclase and cGMP in the regulation of Mrp2-mediated transport in the proximal tubule.
American journal of physiology. Renal physiology 2004;287(1):F33-8.
2004: Sykes Destiny; Sweet Douglas H; Lowes Simon; Nigam Sanjay K; Pritchard John B; Miller David S
Organic anion transport in choroid plexus from wild-type and organic anion transporter 3 (Slc22a8)-null mice.
American journal of physiology. Renal physiology 2004;286(5):F972-8.
2004: Fricker Gert; Miller David S
Modulation of drug transporters at the blood-brain barrier.
Pharmacology 2004;70(4):169-76.
2003: Karnaky Karl John; Hazen-Martin Debra; Miller David S
The xenobiotic transporter, MRP2, in epithelia from insects, sharks, and the human breast: implications for health and disease.
Journal of experimental zoology. Part A, Comparative experimental biology 2003;300(1):91-7.
2003: Miller David S
Confocal imaging of xenobiotic transport across the blood-brain barrier.
Journal of experimental zoology. Part A, Comparative experimental biology 2003;300(1):84-90.
2003: Bauer Björn; Miller David S; Fricker Gert
Compound profiling for P-glycoprotein at the blood-brain barrier using a microplate screening system.
Pharmaceutical research 2003;20(8):1170-6.
2003: Sweet Douglas H; Chan Lauretta M S; Walden Ramsey; Yang Xiao-Ping; Miller David S; Pritchard John B
Organic anion transporter 3 (Slc22a8) is a dicarboxylate exchanger indirectly coupled to the Na+ gradient.
American journal of physiology. Renal physiology 2003;284(4):F763-9.
2002: Fellner Stephan; Bauer Björn; Miller David S; Schaffrik Martina; Fankhänel Martina; Spruss Thilo; Bernhardt Günther; Graeff Claudia; Färber Lothar; Gschaidmeier Harald; Buschauer Armin; Fricker Gert
Transport of paclitaxel (Taxol) across the blood-brain barrier in vitro and in vivo.
The Journal of clinical investigation 2002;110(9):1309-18.
2002: Sweet Douglas H; Miller David S; Pritchard John B; Fujiwara Yuko; Beier David R; Nigam Sanjay K
Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.
The Journal of biological chemistry 2002;277(30):26934-43.
2002: Terlouw Sylvie A; Graeff Claudia; Smeets Pascal H E; Fricker Gert; Russel Frans G M; Masereeuw Rosalinde; Miller David S
Short- and long-term influences of heavy metals on anionic drug efflux from renal proximal tubule.
The Journal of pharmacology and experimental therapeutics 2002;301(2):578-85.
2002: Villalobos Alice R A; Miller David S; Renfro J Larry
Transepithelial organic anion transport by shark choroid plexus.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(5):R1308-16.
2002: Breen Christopher M; Sykes Destiny B; Fricker Gert; Miller David S
Confocal imaging of organic anion transport in intact rat choroid plexus.
American journal of physiology. Renal physiology 2002;282(5):F877-85.
2002: Barnes David M; Sykes Destiny B; Miller David S
Mercuric chloride acting through Mg stimulates protein synthesis in Xenopus oocytes.
Journal of toxicology and environmental health. Part A 2002;65(8):617-29.
2002: Fricker Gert; Nobmann Stephanie; Miller David S
Permeability of porcine blood brain barrier to somatostatin analogues.
British journal of pharmacology 2002;135(5):1308-14.
2002: Notenboom Sylvia; Miller David S; Smits Paul; Russel Frans G M; Masereeuw Rosalinde
Role of NO in endothelin-regulated drug transport in the renal proximal tubule.
American journal of physiology. Renal physiology 2002;282(3):F458-64.
2002: Miller David S; Masereeuw Rosalinde; Karnaky Karl J
Regulation of MRP2-mediated transport in shark rectal salt gland tubules.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(3):R774-81.
2002: Fricker Gert; Miller David S
Relevance of multidrug resistance proteins for intestinal drug absorption in vitro and in vivo.
Pharmacology & toxicology 2002;90(1):5-13.
2002: Miller David S; Graeff Claudia; Droulle Lucy; Fricker Stefanie; Fricker Gert
Xenobiotic efflux pumps in isolated fish brain capillaries.
American journal of physiology. Regulatory, integrative and comparative physiology 2002;282(1):R191-8.
2002: Miller David S
Xenobiotic export pumps, endothelin signaling, and tubular nephrotoxicants--a case of molecular hijacking.
Journal of biochemical and molecular toxicology 2002;16(3):121-7.
2001: Miller D S
Nucleoside phosphonate interactions with multiple organic anion transporters in renal proximal tubule.
The Journal of pharmacology and experimental therapeutics 2001;299(2):567-74.
2001: Sweet D H; Miller D S; Pritchard J B
Ventricular choline transport: a role for organic cation transporter 2 expressed in choroid plexus.
The Journal of biological chemistry 2001;276(45):41611-9.
2001: Terlouw S A; Masereeuw R; Russel F G; Miller D S
Nephrotoxicants induce endothelin release and signaling in renal proximal tubules: effect on drug efflux.
Molecular pharmacology 2001;59(6):1433-40.
2000: Miller D S; Nobmann S N; Gutmann H; Toeroek M; Drewe J; Fricker G
Xenobiotic transport across isolated brain microvessels studied by confocal microscopy.
Molecular pharmacology 2000;58(6):1357-67.
2000: Sweet D H; Miller D S; Pritchard J B
Basolateral localization of organic cation transporter 2 in intact renal proximal tubules.
American journal of physiology. Renal physiology 2000;279(5):F826-34.
2000: Gutmann H; Miller D S; Droulle A; Drewe J; Fahr A; Fricker G
P-glycoprotein- and mrp2-mediated octreotide transport in renal proximal tubule.
British journal of pharmacology 2000;129(2):251-6.
2000: Masereeuw R; Terlouw S A; van Aubel R A; Russel F G; Miller D S
Endothelin B receptor-mediated regulation of ATP-driven drug secretion in renal proximal tubule.
Molecular pharmacology 2000;57(1):59-67.
1999: Pritchard J B; Sweet D H; Miller D S; Walden R
Mechanism of organic anion transport across the apical membrane of choroid plexus.
The Journal of biological chemistry 1999;274(47):33382-7.
1999: Fricker G; Gutmann H; Droulle A; Drewe J; Miller D S
Epithelial transport of anthelmintic ivermectin in a novel model of isolated proximal kidney tubules.
Pharmaceutical research 1999;16(10):1570-5.
1999: Gutmann H; Fricker G; Drewe J; Toeroek M; Miller D S
Interactions of HIV protease inhibitors with ATP-dependent drug export proteins.
Molecular pharmacology 1999;56(2):383-9.
1999: Sweet D H; Miller D S; Pritchard J B
Localization of an organic anion transporter-GFP fusion construct (rROAT1-GFP) in intact proximal tubules.
The American journal of physiology 1999;276(6 Pt 2):F864-73.
1999: Masereeuw R; Moons M M; Toomey B H; Russel F G; Miller D S
Active lucifer yellow secretion in renal proximal tubule: evidence for organic anion transport system crossover.
The Journal of pharmacology and experimental therapeutics 1999;289(2):1104-11.
1999: Miller D S; Villalobos A R; Pritchard J B
Organic cation transport in rat choroid plexus cells studied by fluorescence microscopy.
The American journal of physiology 1999;276(4 Pt 1):C955-68.
1998: Miller D S; Sussman C R; Renfro J L
Protein kinase C regulation of p-glycoprotein-mediated xenobiotic secretion in renal proximal tubule.
The American journal of physiology 1998;275(5 Pt 2):F785-95.
1998: Miller D S; Masereeuw R; Henson J; Karnaky K J
Excretory transport of xenobiotics by dogfish shark rectal gland tubules.
The American journal of physiology 1998;275(3 Pt 2):R697-705.
1998: Miller D S
Protein kinase C regulation of organic anion transport in renal proximal tubule.
The American journal of physiology 1998;274(1 Pt 2):F156-64.
1997: Miller D S; Pritchard J B
Dual pathways for organic anion secretion in renal proximal tubule.
The Journal of experimental zoology 1997;279(5):462-70.
1997: Miller D S; Fricker G; Drewe J
p-Glycoprotein-mediated transport of a fluorescent rapamycin derivative in renal proximal tubule.
The Journal of pharmacology and experimental therapeutics 1997;282(1):440-4.
1997: Li L H; Wine R N; Miller D S; Reece J M; Smith M; Chapin R E
Protection against methoxyacetic-acid-induced spermatocyte apoptosis with calcium channel blockers in cultured rat seminiferous tubules: possible mechanisms.
Toxicology and applied pharmacology 1997;144(1):105-19.
1996: Miller D S; Letcher S; Barnes D M
Fluorescence imaging study of organic anion transport from renal proximal tubule cell to lumen.
The American journal of physiology 1996;271(3 Pt 2):F508-20.
1996: Miller D S; Fricker G; Schramm U; Henson J H; Hager D N; Nundy S; Ballatori N; Boyer J L
Active microtubule-dependent secretion of a fluorescent bile salt derivative in skate hepatocyte clusters.
The American journal of physiology 1996;270(6 Pt 1):G887-96.
1995: Miller D S
Daunomycin secretion by killfish renal proximal tubules.
The American journal of physiology 1995;269(2 Pt 2):R370-9.
1995: Barnes D M; Sykes D B; Smith J J; Miller D S
Magnesium-dependent stimulation of protein synthesis by the insulin mimic, pervanadate.
Journal of cellular physiology 1995;164(2):304-14.
1995: Henson J H; Capuano S; Nesbitt D; Hager D N; Nundy S; Miller D S; Ballatori N; Boyer J L
Cytoskeletal organization in clusters of isolated polarized skate hepatocytes: structural and functional evidence for microtubule-dependent transcytosis.
The Journal of experimental zoology 1995;271(4):273-84.
1995: Schramm U; Fricker G; Wenger R; Miller D S
P-glycoprotein-mediated secretion of a fluorescent cyclosporin analogue by teleost renal proximal tubules.
The American journal of physiology 1995;268(1 Pt 2):F46-52.
1995: Barnes D M; Sykes D B; Shechter Y; Miller D S
Multiple sites of vanadate and peroxovanadate action in Xenopus oocytes.
Journal of cellular physiology 1995;162(1):154-61.
1994: Miller D S; Pritchard J B
Nocodazole inhibition of organic anion secretion in teleost renal proximal tubules.
The American journal of physiology 1994;267(3 Pt 2):R695-704.
1994: Miller D S; Barnes D M; Pritchard J B
Confocal microscopic analysis of fluorescein compartmentation within crab urinary bladder cells.
The American journal of physiology 1994;267(1 Pt 2):R16-25.
1994: Pritchard J B; Sykes D B; Walden R; Miller D S
ATP-dependent transport of tetraethylammonium by endosomes isolated from rat renal cortex.
The American journal of physiology 1994;266(6 Pt 2):F966-76.
1993: Miller D S; Stewart D E; Pritchard J B
Intracellular compartmentation of organic anions within renal cells.
The American journal of physiology 1993;264(5 Pt 2):R882-90.
1992: Wolff N A; Philpot R M; Miller D S; Pritchard J B
Functional expression of renal organic anion transport in Xenopus laevis oocytes.
Molecular and cellular biochemistry 1992;114(1-2):35-41.
1991: Pritchard J B; Miller D S
Comparative insights into the mechanisms of renal organic anion and cation secretion.
The American journal of physiology 1991;261(6 Pt 2):R1329-40.
1991: Miller D S; Pritchard J B
Indirect coupling of organic anion secretion to sodium in teleost (Paralichthys lethostigma) renal tubules.
The American journal of physiology 1991;261(6 Pt 2):R1470-7.
1991: Miller D S; Sykes D B
Stimulation of protein synthesis by internalized insulin.
Journal of cellular physiology 1991;147(3):487-94.
1990: Smith P M; Miller D S; Pritchard J B
Sodium-coupled organic anion transport by Cancer borealis urinary bladder.
The American journal of physiology 1990;259(1 Pt 2):R147-56.
1989: Miller D S; Smith P M; Pritchard J B
Organic anion and cation transport in crab urinary bladder.
The American journal of physiology 1989;257(3 Pt 2):R501-5.
1989: Miller D S
Stimulation of protein synthesis in stage IV Xenopus oocytes by microinjected insulin.
The Journal of biological chemistry 1989;264(18):10438-46.
1988: Smith P M; Pritchard J B; Miller D S
Membrane potential drives organic cation transport into teleost renal proximal tubules.
The American journal of physiology 1988;255(3 Pt 2):R492-9.
1987: Miller D S; Holohan P D
Organic cation secretion in flounder renal tissue.
The American journal of physiology 1987;253(6 Pt 2):R861-7.

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David Miller

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