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Stephen Miller
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38
Dal Canto, Mauro
27
Vanderlugt, Carol
15
Karpus, William
14
Bluestone, Jeffrey
13
Begolka, Wendy Smith
13
Tan, Litjen (L.J)
12
Lipton, Howard
11
Kohm, Adam
11
Neville, Katherine
10
Eagar, Todd
9
Croxford, Ludovic
9
Karandikar, Nitin
9
Peterson, Jeffrey
8
Podojil, Joseph
8
Olson, Julie
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All Publications
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2009: Martin Aaron J; Zhou Liang; Miller Stephen D
MicroRNA--managing the TH-17 inflammatory response.
Nature immunology 2009;10(12):1229-31.
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2009: Podojil Joseph R; Miller Stephen D
Molecular mechanisms of T-cell receptor and costimulatory molecule ligation/blockade in autoimmune disease therapy.
Immunological reviews 2009;229(1):337-55.
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2009: Münz Christian; Lünemann Jan D; Getts Meghann Teague; Miller Stephen D
Antiviral immune responses: triggers of or triggered by autoimmunity?
Nature reviews. Immunology 2009;9(4):246-58.
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2009: Blink Sarah E; Miller Stephen D
The contribution of gammadelta T cells to the pathogenesis of EAE and MS.
Current molecular medicine 2009;9(1):15-22.
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2009: Ekong Udeme D; Miller Stephen D; O'Gorman Maurice R G
In vitro assays of allosensitization.
Pediatric transplantation 2009;13(1):25-34.
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2009: Podojil Joseph R; Miller Stephen D
Cross-linking of CD80 on CD4+ T cells activates a calcium-dependent signaling pathway.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(2):766-73.
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2008: Greene Maria T; Ercolini Anne M; DeGutes Mathew; Miller Stephen D
Differential induction of experimental autoimmune encephalomyelitis by myelin basic protein molecular mimics in mice humanized for HLA-DR2 and an MBP(85-99)-specific T cell receptor.
Journal of autoimmunity 2008;31(4):399-407.
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2008: Schreiner Bettina; Bailey Samantha L; Shin Tahiro; Chen Lieping; Miller Stephen D
PD-1 ligands expressed on myeloid-derived APC in the CNS regulate T-cell responses in EAE.
European journal of immunology 2008;38(10):2706-17.
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2008: Zhang Hong; Podojil Joseph R; Luo Xunrong; Miller Stephen D
Intrinsic and induced regulation of the age-associated onset of spontaneous experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4638-47.
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2008: Luo Xunrong; Pothoven Kathryn L; McCarthy Derrick; DeGutes Mathew; Martin Aaron; Getts Daniel R; Xia Guliang; He Jie; Zhang Xiaomin; Kaufman Dixon B; Miller Stephen D
ECDI-fixed allogeneic splenocytes induce donor-specific tolerance for long-term survival of islet transplants via two distinct mechanisms.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14527-32.
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2008: Nair A; Frederick T J; Miller S D
Astrocytes in multiple sclerosis: a product of their environment.
Cellular and molecular life sciences : CMLS 2008;65(17):2702-20.
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2008: Bailey-Bucktrout Samantha L; Caulkins Sarah C; Goings Gwendolyn; Fischer Jens A A; Dzionek Andrzej; Miller Stephen D
Cutting edge: central nervous system plasmacytoid dendritic cells regulate the severity of relapsing experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6457-61.
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2008: Carpentier Pamela A; Getts Meghann Teague; Miller Stephen D
Pro-inflammatory functions of astrocytes correlate with viral clearance and strain-dependent protection from TMEV-induced demyelinating disease.
Virology 2008;375(1):24-36.
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2008: Podojil Joseph R; Turley Danielle M; Miller Stephen D
Therapeutic blockade of T-cell antigen receptor signal transduction and costimulation in autoimmune disease.
Advances in experimental medicine and biology 2008;640():234-51.
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2008: Goings Gwendolyn E; Greisman Adriana; James Rachel E; Abram Leanne Kf; Begolka Wendy Smith; Miller Stephen D; Szele Francis G
Hematopoietic cell activation in the subventricular zone after Theiler's virus infection.
Journal of neuroinflammation 2008;5():44.
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2007: Ercolini Anne M; Miller Stephen D
Molecular mimics can induce novel self peptide-reactive CD4+ T cell clonotypes in autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):6604-12.
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2007: Miller Stephen D; Turley Danielle M; Podojil Joseph R
Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease.
Nature reviews. Immunology 2007;7(9):665-77.
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2007: Getts Meghann Teague; Kim Byung S; Miller Stephen D
Differential outcome of tolerance induction in naive versus activated Theiler's virus epitope-specific CD8+ cytotoxic T cells.
Journal of virology 2007;81(12):6584-93.
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2007: Miller Stephen D; Karpus William J
Experimental autoimmune encephalomyelitis in the mouse.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2007;Chapter 15():Unit 15.1.
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2007: Ercolini Anne M; Ludovic Croxford J; Degutes Mathew; Miller Stephen D
Cross-reactivity between peptide mimics of the immunodominant myelin proteolipid protein epitope PLP139-151: comparison of peptide priming in CFA vs. viral delivery.
Journal of neuroimmunology 2007;186(1-2):5-18.
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2007: Miller Stephen D; McMahon Eileen J; Schreiner Bettina; Bailey Samantha L
Antigen presentation in the CNS by myeloid dendritic cells drives progression of relapsing experimental autoimmune encephalomyelitis.
Annals of the New York Academy of Sciences 2007;1103():179-91.
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2007: Balabanov Roumen; Strand Krystle; Goswami Rajendra; McMahon Eileen; Begolka Wendy; Miller Stephen D; Popko Brian
Interferon-gamma-oligodendrocyte interactions in the regulation of experimental autoimmune encephalomyelitis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(8):2013-24.
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2007: Turley Danielle M; Miller Stephen D
Peripheral tolerance induction using ethylenecarbodiimide-fixed APCs uses both direct and indirect mechanisms of antigen presentation for prevention of experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(4):2212-20.
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2007: Lin Wensheng; Bailey Samantha L; Ho Hanson; Harding Heather P; Ron David; Miller Stephen D; Popko Brian
The integrated stress response prevents demyelination by protecting oligodendrocytes against immune-mediated damage.
The Journal of clinical investigation 2007;117(2):448-56.
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2007: Bailey Samantha L; Schreiner Bettina; McMahon Eileen J; Miller Stephen D
CNS myeloid DCs presenting endogenous myelin peptides 'preferentially' polarize CD4+ T(H)-17 cells in relapsing EAE.
Nature immunology 2007;8(2):172-80.
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2007: Carpentier Pamela A; Williams Bryan R; Miller Stephen D
Distinct roles of protein kinase R and toll-like receptor 3 in the activation of astrocytes by viral stimuli.
Glia 2007;55(3):239-52.
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2007: Bennett Jami L; Elhofy Adam; Charo Israel; Miller Stephen D; Dal Canto Mauro C; Karpus William J
CCR2 regulates development of Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Viral immunology 2007;20(1):19-33.
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2006: Croxford J Ludovic; Ercolini Anne M; Degutes Mathew; Miller Stephen D
Structural requirements for initiation of cross-reactivity and CNS autoimmunity with a PLP139-151 mimic peptide derived from murine hepatitis virus.
European journal of immunology 2006;36(10):2671-80.
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2006: Podojil Joseph R; Kohm Adam P; Miller Stephen D
CD4+ T cell expressed CD80 regulates central nervous system effector function and survival during experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(5):2948-58.
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2006: McMahon Eileen J; Bailey Samantha L; Miller Stephen D
CNS dendritic cells: critical participants in CNS inflammation?
Neurochemistry international 2006;49(2):195-203.
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2006: Kohm Adam P; McMahon Jeffrey S; Podojil Joseph R; Begolka Wendy Smith; DeGutes Mathew; Kasprowicz Deborah J; Ziegler Steven F; Miller Stephen D
Cutting Edge: Anti-CD25 monoclonal antibody injection results in the functional inactivation, not depletion, of CD4+CD25+ T regulatory cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3301-5.
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2006: Ercolini Anne M; Miller Stephen D
Mechanisms of immunopathology in murine models of central nervous system demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(6):3293-8.
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2006: Bailey Samantha L; Carpentier Pamela A; McMahon Eileen J; Begolka Wendy Smith; Miller Stephen D
Innate and adaptive immune responses of the central nervous system.
Critical reviews in immunology 2006;26(2):149-88.
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2005: Croxford J Ludovic; Wang Kegiang; Miller Stephen D; Engman David M; Tyler Kevin M
Effects of cannabinoid treatment on Chagas disease pathogenesis: balancing inhibition of parasite invasion and immunosuppression.
Cellular microbiology 2005;7(11):1592-602.
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2005: Ercolini Anne M; Miller Stephen D
Role of immunologic cross-reactivity in neurological diseases.
Neurological research 2005;27(7):726-33.
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2005: Kohm Adam P; Turley Danielle M; Miller Stephen D
Targeting the TCR: T-cell receptor and peptide-specific tolerance-based strategies for restoring self-tolerance in CNS autoimmune disease.
International reviews of immunology 2005;24(5-6):361-92.
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2005: Smith Cassandra E; Eagar Todd N; Strominger Jack L; Miller Stephen D
Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(27):9595-600.
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2005: Croxford J Ludovic; Olson Julie K; Anger Holly A; Miller Stephen D
Initiation and exacerbation of autoimmune demyelination of the central nervous system via virus-induced molecular mimicry: implications for the pathogenesis of multiple sclerosis.
Journal of virology 2005;79(13):8581-90.
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2005: Kohm Adam P; Podojil Joseph R; Williams Julie S; McMahon Jeffrey S; Miller Stephen D
CD28 regulates glucocorticoid-induced TNF receptor family-related gene expression on CD4+ T cells via IL-2-dependent mechanisms.
Cellular immunology 2005;235(1):56-64.
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2005: Howard Laurence M; Kohm Adam P; Castaneda Carol L; Miller Stephen D
Therapeutic blockade of TCR signal transduction and co-stimulation in autoimmune disease.
Current drug targets. Inflammation and allergy 2005;4(2):205-16.
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2005: Kohm Adam P; Williams Julie S; Bickford Allison L; McMahon Jeffrey S; Chatenoud Lucienne; Bach Jean-François; Bluestone Jeffrey A; Miller Stephen D
Treatment with nonmitogenic anti-CD3 monoclonal antibody induces CD4+ T cell unresponsiveness and functional reversal of established experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(8):4525-34.
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2005: McMahon Eileen J; Bailey Samantha L; Castenada Carol Vanderlugt; Waldner Hanspeter; Miller Stephen D
Epitope spreading initiates in the CNS in two mouse models of multiple sclerosis.
Nature medicine 2005;11(3):335-9.
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2005: Carpentier Pamela A; Begolka Wendy Smith; Olson Julie K; Elhofy Adam; Karpus William J; Miller Stephen D
Differential activation of astrocytes by innate and adaptive immune stimuli.
Glia 2005;49(3):360-74.
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2005: Olson J K; Ercolini A M; Miller S D
A virus-induced molecular mimicry model of multiple sclerosis.
Current topics in microbiology and immunology 2005;296():39-53.
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2004: Olson Julie K; Miller Stephen D
Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3916-24.
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2004: Eagar Todd N; Turley Danielle M; Padilla Josette; Karandikar Nitin J; Tan Litjen; Bluestone Jeffrey A; Miller Stephen D
CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(12):7442-50.
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2004: Kohm Adam P; Williams Julie S; Miller Stephen D
Cutting edge: ligation of the glucocorticoid-induced TNF receptor enhances autoreactive CD4+ T cell activation and experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(8):4686-90.
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2004: Olson Julie K; Ludovic Croxford J; Miller Stephen D
Innate and adaptive immune requirements for induction of autoimmune demyelinating disease by molecular mimicry.
Molecular immunology 2004;40(14-15):1103-8.
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2004: Fuller Kevin G; Olson Julie K; Howard Laurence M; Croxford J Ludovic; Miller Stephen D
Mouse models of multiple sclerosis: experimental autoimmune encephalomyelitis and Theiler's virus-induced demyelinating disease.
Methods in molecular medicine 2004;102():339-61.
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2003: Theien Bradley E; Vanderlugt Carol L; Nickerson-Nutter Cheryl; Cornebise Mark; Scott Daniel M; Perper Stuart J; Whalley Eric T; Miller Stephen D
Differential effects of treatment with a small-molecule VLA-4 antagonist before and after onset of relapsing EAE.
Blood 2003;102(13):4464-71.
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2003: Kohm Adam P; Miller Stephen D
Role of ICAM-1 and P-selectin expression in the development and effector function of CD4+CD25+regulatory T cells.
Journal of autoimmunity 2003;21(3):261-71.
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2003: Olson Julie K; Zamvil Scott S; Miller Stephen D
Efficient technique for immortalization of murine microglial cells relevant for studies in murine models of multiple sclerosis.
Journal of neuroscience methods 2003;128(1-2):33-43.
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2003: Croxford J Ludovic; Miller Stephen D
Immunoregulation of a viral model of multiple sclerosis using the synthetic cannabinoid R+WIN55,212.
The Journal of clinical investigation 2003;111(8):1231-40.
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2003: Kohm Adam P; Fuller Kevin G; Miller Stephen D
Mimicking the way to autoimmunity: an evolving theory of sequence and structural homology.
Trends in microbiology 2003;11(3):101-5.
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2003: Howard Laurence M; Neville Katherine L; Haynes Lia M; Dal Canto Mauro C; Miller Stephen D
CD154 blockade results in transient reduction in Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of virology 2003;77(3):2247-50.
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2003: Kohm Adam P; Carpentier Pamela A; Miller Stephen D
Regulation of experimental autoimmune encephalomyelitis (EAE) by CD4+CD25+ regulatory T cells.
Novartis Foundation symposium 2003;252():45-52; discussion 52-4, 106-14.
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2002: Kohm Adam P; Carpentier Pamela A; Anger Holly A; Miller Stephen D
Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):4712-6.
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2002: Croxford J Ludovic; Olson Julie K; Miller Stephen D
Epitope spreading and molecular mimicry as triggers of autoimmunity in the Theiler's virus-induced demyelinating disease model of multiple sclerosis.
Autoimmunity reviews 2002;1(5):251-60.
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2002: Olson Julie K; Eagar Todd N; Miller Stephen D
Functional activation of myelin-specific T cells by virus-induced molecular mimicry.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(5):2719-26.
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2002: Howard Laurence M; Dal Canto Mauro C; Miller Stephen D
Transient anti-CD154-mediated immunotherapy of ongoing relapsing experimental autoimmune encephalomyelitis induces long-term inhibition of disease relapses.
Journal of neuroimmunology 2002;129(1-2):58-65.
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2002: Girvin Ann M; Gordon Kenneth B; Welsh C Jane; Clipstone Neil A; Miller Stephen D
Differential abilities of central nervous system resident endothelial cells and astrocytes to serve as inducible antigen-presenting cells.
Blood 2002;99(10):3692-701.
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2002: Tompkins S Mark; Fuller Kevin G; Miller Stephen D
Theiler's virus-mediated autoimmunity: local presentation of CNS antigens and epitope spreading.
Annals of the New York Academy of Sciences 2002;958():26-38.
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2002: Eagar Todd N; Karandikar Nitin J; Bluestone Jeffrey A; Miller Stephen D
The role of CTLA-4 in induction and maintenance of peripheral T cell tolerance.
European journal of immunology 2002;32(4):972-81.
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2002: Girvin Ann M; Dal Canto Mauro C; Miller Stephen D
CD40/CD40L interaction is essential for the induction of EAE in the absence of CD28-mediated co-stimulation.
Journal of autoimmunity 2002;18(2):83-94.
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2002: Vanderlugt Carol L; Miller Stephen D
Epitope spreading in immune-mediated diseases: implications for immunotherapy.
Nature reviews. Immunology 2002;2(2):85-95.
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2002: Neville Katherine L; Padilla Josette; Miller Stephen D
Myelin-specific tolerance attenuates the progression of a virus-induced demyelinating disease: implications for the treatment of MS.
Journal of neuroimmunology 2002;123(1-2):18-29.
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2002: Howard Laurence M; Ostrovidov Serge; Smith Cassandra E; Dal Canto Mauro C; Miller Stephen D
Normal Th1 development following long-term therapeutic blockade of CD154-CD40 in experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2002;109(2):233-41.
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2001: Wang K; Busker-Mannie A E; Hoeft J; Vasquez K; Miller S D; Melvold R W; Waltenbaugh C
Prolonged Hya-disparate skin graft survival in ethanol-consuming mice: correlation with impaired delayed hypersensitivity.
Alcoholism, clinical and experimental research 2001;25(10):1542-8.
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2001: Begolka W S; Haynes L M; Olson J K; Padilla J; Neville K L; Dal Canto M; Palma J; Kim B S; Miller S D
CD8-deficient SJL mice display enhanced susceptibility to Theiler's virus infection and increased demyelinating pathology.
Journal of neurovirology 2001;7(5):409-20.
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2001: Olson J K; Girvin A M; Miller S D
Direct activation of innate and antigen-presenting functions of microglia following infection with Theiler's virus.
Journal of virology 2001;75(20):9780-9.
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2001: Salomon B; Rhee L; Bour-Jordan H; Hsin H; Montag A; Soliven B; Arcella J; Girvin A M; Padilla J; Miller S D; Bluestone J A
Development of spontaneous autoimmune peripheral polyneuropathy in B7-2-deficient NOD mice.
The Journal of experimental medicine 2001;194(5):677-84.
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2001: Olson J K; Croxford J L; Calenoff M A; Dal Canto M C; Miller S D
A virus-induced molecular mimicry model of multiple sclerosis.
The Journal of clinical investigation 2001;108(2):311-8.
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2001: Palma J P; Lee H G; Mohindru M; Kang B S; Dal Canto M; Miller S D; Kim B S
Enhanced susceptibility to Theiler's virus-induced demyelinating disease in perforin-deficient mice.
Journal of neuroimmunology 2001;116(2):125-35.
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2001: Miller S D; Olson J K; Croxford J L
Multiple pathways to induction of virus-induced autoimmune demyelination: lessons from Theiler's virus infection.
Journal of autoimmunity 2001;16(3):219-27.
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2001: Theien B E; Vanderlugt C L; Eagar T N; Nickerson-Nutter C; Nazareno R; Kuchroo V K; Miller S D
Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2001;107(8):995-1006.
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2001: Howard L M; Miller S D
Autoimmune intervention by CD154 blockade prevents T cell retention and effector function in the target organ.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(3):1547-53.
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2001: Olson J K; Croxford J L; Miller S D
Virus-induced autoimmunity: potential role of viruses in initiation, perpetuation, and progression of T-cell-mediated autoimmune disease.
Viral immunology 2001;14(3):227-50.
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2001: Miller S D; Eagar T N
Functional role of epitope spreading in the chronic pathogenesis of autoimmune and virus-induced demyelinating diseases.
Advances in experimental medicine and biology 2001;490():99-107.
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2001: Miller S D; Katz-Levy Y; Neville K L; Vanderlugt C L
Virus-induced autoimmunity: epitope spreading to myelin autoepitopes in Theiler's virus infection of the central nervous system.
Advances in virus research 2001;56():199-217.
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2000: Katz-Levy Y; Neville K L; Padilla J; Rahbe S; Begolka W S; Girvin A M; Olson J K; Vanderlugt C L; Miller S D
Temporal development of autoreactive Th1 responses and endogenous presentation of self myelin epitopes by central nervous system-resident APCs in Theiler's virus-infected mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5304-14.
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2000: Suvannavejh G C; Lee H O; Padilla J; Dal Canto M C; Barrett T A; Miller S D
Divergent roles for p55 and p75 tumor necrosis factor receptors in the pathogenesis of MOG(35-55)-induced experimental autoimmune encephalomyelitis.
Cellular immunology 2000;205(1):24-33.
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2000: Karandikar N J; Eagar T N; Vanderlugt C L; Bluestone J A; Miller S D
CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 2000;109(2):173-80.
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2000: Neville K L; Dal Canto M C; Bluestone J A; Miller S D
CD28 costimulatory blockade exacerbates disease severity and accelerates epitope spreading in a virus-induced autoimmune disease.
Journal of virology 2000;74(18):8349-57.
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2000: Lee H O; Miller S D; Hurst S D; Tan L J; Cooper C J; Barrett T A
Interferon gamma induction during oral tolerance reduces T-cell migration to sites of inflammation.
Gastroenterology 2000;119(1):129-38.
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2000: Haynes L M; Vanderlugt C L; Dal Canto M C; Melvold R W; Miller S D
CD8(+) T cells from Theiler's virus-resistant BALB/cByJ mice downregulate pathogenic virus-specific CD4(+) T cells.
Journal of neuroimmunology 2000;106(1-2):43-52.
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2000: Vanderlugt C L; Rahbe S M; Elliott P J; Dal Canto M C; Miller S D
Treatment of established relapsing experimental autoimmune encephalomyelitis with the proteasome inhibitor PS-519.
Journal of autoimmunity 2000;14(3):205-11.
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2000: Dal Canto M C; Calenoff M A; Miller S D; Vanderlugt C L
Lymphocytes from mice chronically infected with Theiler's murine encephalomyelitis virus produce demyelination of organotypic cultures after stimulation with the major encephalitogenic epitope of myelin proteolipid protein. Epitope spreading in TMEV infection has functional activity.
Journal of neuroimmunology 2000;104(1):79-84.
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2000: Suvannavejh G C; Dal Canto M C; Matis L A; Miller S D
Fas-mediated apoptosis in clinical remissions of relapsing experimental autoimmune encephalomyelitis.
The Journal of clinical investigation 2000;105(2):223-31.
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2000: Vanderlugt C L; Neville K L; Nikcevich K M; Eagar T N; Bluestone J A; Miller S D
Pathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):670-8.
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2000: Girvin A M; Dal Canto M C; Rhee L; Salomon B; Sharpe A; Bluestone J A; Miller S D
A critical role for B7/CD28 costimulation in experimental autoimmune encephalomyelitis: a comparative study using costimulatory molecule-deficient mice and monoclonal antibody blockade.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(1):136-43.
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1999: Hoffman L M; Fife B T; Begolka W S; Miller S D; Karpus W J
Central nervous system chemokine expression during Theiler's virus-induced demyelinating disease.
Journal of neurovirology 1999;5(6):635-42.
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1999: Katz-Levy Y; Neville K L; Girvin A M; Vanderlugt C L; Pope J G; Tan L J; Miller S D
Endogenous presentation of self myelin epitopes by CNS-resident APCs in Theiler's virus-infected mice.
The Journal of clinical investigation 1999;104(5):599-610.
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1999: Nicholson S M; Haynes L M; Vanderlugt C L; Miller S D; Melvold R W
The role of protective CD8+ T cells in resistance of BALB/c mice to Theiler's murine encephalomyelitis virus-induced demyelinating disease: regulatory vs. lytic.
Journal of neuroimmunology 1999;98(2):136-46.
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1999: Howard L M; Miga A J; Vanderlugt C L; Dal Canto M C; Laman J D; Noelle R J; Miller S D
Mechanisms of immunotherapeutic intervention by anti-CD40L (CD154) antibody in an animal model of multiple sclerosis.
The Journal of clinical investigation 1999;103(2):281-90.
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1998: Begolka W S; Miller S D
Cytokines as intrinsic and exogenous regulators of pathogenesis in experimental autoimmune encephalomyelitis.
Research in immunology 1998;149(9):771-81; discussion 843-4, 855-60.
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1998: Begolka W S; Vanderlugt C L; Rahbe S M; Miller S D
Differential expression of inflammatory cytokines parallels progression of central nervous system pathology in two clinically distinct models of multiple sclerosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):4437-46.
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1998: Pope J G; Vanderlugt C L; Rahbe S M; Lipton H L; Miller S D
Characterization of and functional antigen presentation by central nervous system mononuclear cells from mice infected with Theiler's murine encephalomyelitis virus.
Journal of virology 1998;72(10):7762-71.
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1998: Vanderlugt C L; Begolka W S; Neville K L; Katz-Levy Y; Howard L M; Eagar T N; Bluestone J A; Miller S D
The functional significance of epitope spreading and its regulation by co-stimulatory molecules.
Immunological reviews 1998;164():63-72.
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1998: Karandikar N J; Vanderlugt C L; Bluestone J A; Miller S D
Targeting the B7/CD28:CTLA-4 costimulatory system in CNS autoimmune disease.
Journal of neuroimmunology 1998;89(1-2):10-8.
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1998: Karandikar N J; Vanderlugt C L; Eagar T; Tan L; Bluestone J A; Miller S D
Tissue-specific up-regulation of B7-1 expression and function during the course of murine relapsing experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):192-9.
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1998: Tan L; Gordon K B; Mueller J P; Matis L A; Miller S D
Presentation of proteolipid protein epitopes and B7-1-dependent activation of encephalitogenic T cells by IFN-gamma-activated SJL/J astrocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4271-9.
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1998: Burt R K; Padilla J; Begolka W S; Canto M C; Miller S D
Effect of disease stage on clinical outcome after syngeneic bone marrow transplantation for relapsing experimental autoimmune encephalomyelitis.
Blood 1998;91(7):2609-16.
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1998: Tan L J; Vanderlugt C L; McRae B L; Miller S D
Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. III. A role for anergy/deletion.
Autoimmunity 1998;27(1):13-28.
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1997: Vanderlugt C L; Karandikar N J; Lenschow D J; Dal Canto M C; Bluestone J A; Miller S D
Treatment with intact anti-B7-1 mAb during disease remission enhances epitope spreading and exacerbates relapses in R-EAE.
Journal of neuroimmunology 1997;79(2):113-8.
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1997: Miller S D; Vanderlugt C L; Begolka W S; Pao W; Yauch R L; Neville K L; Katz-Levy Y; Carrizosa A; Kim B S
Persistent infection with Theiler's virus leads to CNS autoimmunity via epitope spreading.
Nature medicine 1997;3(10):1133-6.
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1997: Kennedy K J; Smith W S; Miller S D; Karpus W J
Induction of antigen-specific tolerance for the treatment of ongoing, relapsing autoimmune encephalomyelitis: a comparison between oral and peripheral tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(2):1036-44.
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1997: Miller S D; Vanderlugt C L; Begolka W S; Pao W; Neville K L; Yauch R L; Kim B S
Epitope spreading leads to myelin-specific autoimmune responses in SJL mice chronically infected with Theiler's virus.
Journal of neurovirology 1997;3 Suppl 1():S62-5.
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1997: McRae B L; Karandikar N J; Miller S D
Degenerate antigen recognition by CD4+ effector T cells in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1997;75(1-2):156-62.
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1997: Nikcevich K M; Gordon K B; Tan L; Hurst S D; Kroepfl J F; Gardinier M; Barrett T A; Miller S D
IFN-gamma-activated primary murine astrocytes express B7 costimulatory molecules and prime naive antigen-specific T cells.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):614-21.
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1996: Karpus W J; Kennedy K J; Smith W S; Miller S D
Inhibition of relapsing experimental autoimmune encephalomyelitis in SJL mice by feeding the immunodominant PLP139-151 peptide.
Journal of neuroscience research 1996;45(4):410-23.
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1996: Karandikar N J; Vanderlugt C L; Walunas T L; Miller S D; Bluestone J A
CTLA-4: a negative regulator of autoimmune disease.
The Journal of experimental medicine 1996;184(2):783-8.
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1996: Pope J G; Karpus W J; VanderLugt C; Miller S D
Flow cytometric and functional analyses of central nervous system-infiltrating cells in SJL/J mice with Theiler's virus-induced demyelinating disease. Evidence for a CD4+ T cell-mediated pathology.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(10):4050-8.
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1996: Nicholson S M; Dal Canto M C; Miller S D; Melvold R W
Adoptively transferred CD8+ T lymphocytes provide protection against TMEV-induced demyelinating disease in BALB/c mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(3):1276-83.
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1995: Miller S D; Vanderlugt C L; Lenschow D J; Pope J G; Karandikar N J; Dal Canto M C; Bluestone J A
Blockade of CD28/B7-1 interaction prevents epitope spreading and clinical relapses of murine EAE.
Immunity 1995;3(6):739-45.
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1995: Pullen L C; Park S H; Miller S D; Dal Canto M C; Kim B S
Treatment with bacterial LPS renders genetically resistant C57BL/6 mice susceptible to Theiler's virus-induced demyelinating disease.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(9):4497-503.
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1995: Karpus W J; Lukacs N W; McRae B L; Strieter R M; Kunkel S L; Miller S D
An important role for the chemokine macrophage inflammatory protein-1 alpha in the pathogenesis of the T cell-mediated autoimmune disease, experimental autoimmune encephalomyelitis.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(10):5003-10.
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1995: Dal Canto M C; Melvold R W; Kim B S; Miller S D
Two models of multiple sclerosis: experimental allergic encephalomyelitis (EAE) and Theiler's murine encephalomyelitis virus (TMEV) infection. A pathological and immunological comparison.
Microscopy research and technique 1995;32(3):215-29.
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1995: Karpus W J; Pope J G; Peterson J D; Dal Canto M C; Miller S D
Inhibition of Theiler's virus-mediated demyelination by peripheral immune tolerance induction.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(2):947-57.
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1995: McRae B L; Nikcevich K M; Karpus W J; Hurst S D; Miller S D
Differential recognition of peptide analogs by naive verses activated PLP 139-151-specific CD4+ T cells.
Journal of neuroimmunology 1995;60(1-2):17-28.
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1995: McRae B L; Vanderlugt C L; Dal Canto M C; Miller S D
Functional evidence for epitope spreading in the relapsing pathology of experimental autoimmune encephalomyelitis.
The Journal of experimental medicine 1995;182(1):75-85.
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1995: Miller S D; McRae B L; Vanderlugt C L; Nikcevich K M; Pope J G; Pope L; Karpus W J
Evolution of the T-cell repertoire during the course of experimental immune-mediated demyelinating diseases.
Immunological reviews 1995;144():225-44.
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1994: Pullen L C; Miller S D; Dal Canto M C; Van der Meide P H; Kim B S
Alteration in the level of interferon-gamma results in acceleration of Theiler's virus-induced demyelinating disease.
Journal of neuroimmunology 1994;55(2):143-52.
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1994: McRae B L; Miller S D
Fine specificity of CD4+ T cell responses to the dominant encephalitogenic PLP 139-151 peptide in SJL/J mice.
Neurochemical research 1994;19(8):997-1004.
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1994: Nicholson S M; Peterson J D; Miller S D; Wang K; Dal Canto M C; Melvold R W
BALB/c substrain differences in susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of neuroimmunology 1994;52(1):19-24.
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1994: Tibbetts R S; Kim I Y; Olson C L; Barthel L M; Sullivan M A; Winquist A G; Miller S D; Engman D M
Molecular cloning and characterization of the 78-kilodalton glucose-regulated protein of Trypanosoma cruzi.
Infection and immunity 1994;62(6):2499-507.
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1994: Karpus W J; Peterson J D; Miller S D
Anergy in vivo: down-regulation of antigen-specific CD4+ Th1 but not Th2 cytokine responses.
International immunology 1994;6(5):721-30.
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1994: Malotky M K; Paterson P Y; Miller S D
Differential recognition of sequences within the encephalitogenic region of myelin basic protein capable of eliciting cell-mediated immune responses in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1994;51(1):109.
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1994: Tibbetts R S; McCormick T S; Rowland E C; Miller S D; Engman D M
Cardiac antigen-specific autoantibody production is associated with cardiomyopathy in Trypanosoma cruzi-infected mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):1493-9.
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1994: Gerety S J; Karpus W J; Cubbon A R; Goswami R G; Rundell M K; Peterson J D; Miller S D
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. V. Mapping of a dominant immunopathologic VP2 T cell epitope in susceptible SJL/J mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):908-18.
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1994: Gerety S J; Rundell M K; Dal Canto M C; Miller S D
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. VI. Potentiation of demyelination with and characterization of an immunopathologic CD4+ T cell line specific for an immunodominant VP2 epitope.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):919-29.
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1993: Malotky M K; Paterson P Y; Miller S D
Differential recognition of sequences within the encephalitogenic region of myelin basic protein capable of eliciting cell-mediated immune responses in experimental autoimmune encephalomyelitis.
Journal of neuroimmunology 1993;48(2):135-42.
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1993: Pullen L C; Miller S D; Dal Canto M C; Kim B S
Class I-deficient resistant mice intracerebrally inoculated with Theiler's virus show an increased T cell response to viral antigens and susceptibility to demyelination.
European journal of immunology 1993;23(9):2287-93.
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1993: Peterson J D; Karpus W J; Clatch R J; Miller S D
Split tolerance of Th1 and Th2 cells in tolerance to Theiler's murine encephalomyelitis virus.
European journal of immunology 1993;23(1):46-55.
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1992: McRae B L; Kennedy M K; Tan L J; Dal Canto M C; Picha K S; Miller S D
Induction of active and adoptive relapsing experimental autoimmune encephalomyelitis (EAE) using an encephalitogenic epitope of proteolipid protein.
Journal of neuroimmunology 1992;38(3):229-40.
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1992: Tan L J; Kennedy M K; Miller S D
Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction. II. Fine specificity of effector T cell inhibition.
Journal of immunology (Baltimore, Md. : 1950) 1992;148(9):2748-55.
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1992: Pope L; Paterson P Y; Miller S D
Antigen-specific inhibition of the adoptive transfer of experimental autoimmune encephalomyelitis in Lewis rats.
Journal of neuroimmunology 1992;37(3):177-89.
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1992: Peterson J D; Waltenbaugh C; Miller S D
IgG subclass responses to Theiler's murine encephalomyelitis virus infection and immunization suggest a dominant role for Th1 cells in susceptible mouse strains.
Immunology 1992;75(4):652-8.
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1992: Miller S D; Tan L J; Pope L; McRae B L; Karpus W J
Antigen-specific tolerance as a therapy for experimental autoimmune encephalomyelitis.
International reviews of immunology 1992;9(3):203-22.
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1991: Miller S D; Tan L J; Kennedy M K; Dal Canto M C
Specific immunoregulation of the induction and effector stages of relapsing EAE via neuroantigen-specific tolerance induction.
Annals of the New York Academy of Sciences 1991;636():79-94.
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1991: Tan L J; Kennedy M K; Dal Canto M C; Miller S D
Successful treatment of paralytic relapses in adoptive experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(6):1797-802.
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1991: Lipton H L; Calenoff M; Bandyopadhyay P; Miller S D; Dal Canto M C; Gerety S; Jensen K
The 5' noncoding sequences from a less virulent Theiler's virus dramatically attenuate GDVII neurovirulence.
Journal of virology 1991;65(8):4370-7.
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1991: Da Canto M C; Kennedy M K; Tan L J; Miller S D
Immune regulation by tolerization in EAE and in Theiler's murine encephalomyelitis virus (TMEV) infection (1).
Acta neurologica 1991;13(2):107-112.
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1991: Gerety S J; Clatch R J; Lipton H L; Goswami R G; Rundell M K; Miller S D
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus-induced demyelinating disease. IV. Identification of an immunodominant T cell determinant on the N-terminal end of the VP2 capsid protein in susceptible SJL/J mice.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2401-8.
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1990: Kennedy M K; Tan L J; Dal Canto M C; Miller S D
Regulation of the effector stages of experimental autoimmune encephalomyelitis via neuroantigen-specific tolerance induction.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(1):117-26.
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1990: Clatch R J; Miller S D; Metzner R; Dal Canto M C; Lipton H L
Monocytes/macrophages isolated from the mouse central nervous system contain infectious Theiler's murine encephalomyelitis virus (TMEV).
Virology 1990;176(1):244-54.
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1990: Melvold R W; Jokinen D M; Miller S D; Dal Canto M C; Lipton H L
Identification of a locus on mouse chromosome 3 involved in differential susceptibility to Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Journal of virology 1990;64(2):686-90.
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1990: Peterson J D; Miller S D; Waltenbaugh C
Rapid biotin-avidin method for quantitation of antiviral antibody isotypes.
Journal of virological methods 1990;27(2):189-201.
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1990: Kennedy M K; Tan L J; Dal Canto M C; Tuohy V K; Lu Z J; Trotter J L; Miller S D
Inhibition of murine relapsing experimental autoimmune encephalomyelitis by immune tolerance to proteolipid protein and its encephalitogenic peptides.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(3):909-15.
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1990: Busker A E; Miller S D; Melvold R W
Induction of allograft tolerance to the H-Y antigen in adult C57BL/6 mice: differential effects on delayed-type hypersensitivity and cytolytic T-lymphocyte activity.
Cellular immunology 1990;125(1):225-34.
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1990: Miller S D; Gerety S J; Kennedy M K; Peterson J D; Trotter J L; Tuohy V K; Waltenbaugh C; Dal Canto M C; Lipton H L
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. III. Failure of neuroantigen-specific immune tolerance to affect the clinical course of demyelination.
Journal of neuroimmunology 1990;26(1):9-23.
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1989: Peterson J D; Kim J Y; Melvold R W; Miller S D; Waltenbaugh C
A rapid method for quantitation of antiviral antibodies.
Journal of immunological methods 1989;119(1):83-94.
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1988: Kennedy M K; Dal Canto M C; Trotter J L; Miller S D
Specific immune regulation of chronic-relapsing experimental allergic encephalomyelitis in mice.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(9):2986-93.
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1988: Miller S D; Clatch R J; Lipton H L
Fine specificity of T-cell-mediated immune responses of susceptible and resistant strains in Theiler's murine encephalomyelitis virus-induced demyelinating disease.
Annals of the New York Academy of Sciences 1988;540():674-7.
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1987: Clatch R J; Pevear D C; Rozhon E; Roos R P; Miller S D; Lipton H L
Characterization and specificity of humoral immune responses to Theiler's murine encephalomyelitis virus capsid proteins.
The Journal of general virology 1987;68 ( Pt 12)():3191-6.
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1987: Clatch R J; Lipton H L; Miller S D
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. II. Survey of host immune responses and central nervous system virus titers in inbred mouse strains.
Microbial pathogenesis 1987;3(5):327-37.
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1987: Kennedy M K; Clatch R J; Dal Canto M C; Trotter J L; Miller S D
Monoclonal antibody-induced inhibition of relapsing EAE in SJL/J mice correlates with inhibition of neuroantigen-specific cell-mediated immune responses.
Journal of neuroimmunology 1987;16(3):345-64.
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1987: Clatch R J; Melvold R W; Dal Canto M C; Miller S D; Lipton H L
The Theiler's murine encephalomyelitis virus (TMEV) model for multiple sclerosis shows a strong influence of the murine equivalents of HLA-A, B, and C.
Journal of neuroimmunology 1987;15(2):121-35.
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1987: Stuart P M; Iannaccone P M; Miller S D; Jenkins M K; Del Muro F A; Melvold R W
In vitro and in vivo correlates of hybrid tumor resistance.
Journal of the National Cancer Institute 1987;78(6):1159-68.
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1987: Miller S D; Clatch R J; Pevear D C; Trotter J L; Lipton H L
Class II-restricted T cell responses in Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease. I. Cross-specificity among TMEV substrains and related picornaviruses, but not myelin proteins.
Journal of immunology (Baltimore, Md. : 1950) 1987;138(11):3776-84.
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1986: Clatch R J; Lipton H L; Miller S D
Characterization of Theiler's murine encephalomyelitis virus (TMEV)-specific delayed-type hypersensitivity responses in TMEV-induced demyelinating disease: correlation with clinical signs.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(3):920-7.
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1985: Clatch R J; Melvold R W; Miller S D; Lipton H L
Theiler's murine encephalomyelitis virus (TMEV)-induced demyelinating disease in mice is influenced by the H-2D region: correlation with TEMV-specific delayed-type hypersensitivity.
Journal of immunology (Baltimore, Md. : 1950) 1985;135(2):1408-14.
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1985: Jenkins M K; Miller S D
Immunoregulatory pathways in adult responder mice. III. Establishment of a GAT-specific suppressor T cell clone from GAT-tolerant responders which afferently regulates DTH responses.
The Journal of molecular and cellular immunology : JMCI 1985;2(1):1-13.
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