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Walter Miller

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Disorders

Congenital Adrenal Hyperplasia

Concepts & Ideas

Molecular Sequence Data

Physiology

Genes & Molecular Sequences

Amino Acid Sequence

Anatomy

Procedures

Molecular Cloning

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Co-Publications
Name
15
Huang, Ningwu
14
Bose, Himangshu
13
Auchus, Richard
13
Portale, Anthony
12
Chung, Bon-Chu
10
Gitelman, Stephen
10
Mellon, Synthia
8
Flück, Christa
8
Bristow, James
7
Geller, David
7
Strauss, Jerome
7
Tee, Meng Kian
7
Black, Stephen Matthew
7
Pandey, Amit
6
Fardella, Carlos

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Publications

TOP 3
Ranadive Sayali A; Ersoy Baran; Favre Helene; Cheung Clement C; Rosenthal Stephen M; Miller Walter L; Vaisse Christian
Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.
Sahakitrungruang Taninee; Tee Meng Kian; Speiser Phyllis W; Miller Walter L
Novel P450c17 mutation H373D causing combined 17alpha-hydroxylase/17,20-lyase deficiency.
Miller Walter L; Huang Ningwu; Agrawal Vishal; Giacomini Kathleen M
Genetic variation in human P450 oxidoreductase.

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All Publications

2009: Ranadive Sayali A; Ersoy Baran; Favre Helene; Cheung Clement C; Rosenthal Stephen M; Miller Walter L; Vaisse Christian
Identification, characterization and rescue of a novel vasopressin-2 receptor mutation causing nephrogenic diabetes insipidus.
Clinical endocrinology 2009;71(3):388-93.
2009: Sahakitrungruang Taninee; Tee Meng Kian; Speiser Phyllis W; Miller Walter L
Novel P450c17 mutation H373D causing combined 17alpha-hydroxylase/17,20-lyase deficiency.
The Journal of clinical endocrinology and metabolism 2009;94(8):3089-92.
2009: Miller Walter L; Huang Ningwu; Agrawal Vishal; Giacomini Kathleen M
Genetic variation in human P450 oxidoreductase.
Molecular and cellular endocrinology 2009;300(1-2):180-4.
2009: Miller Walter L
Androgen synthesis in adrenarche.
Reviews in endocrine & metabolic disorders 2009;10(1):3-17.
2009: Gomes Larissa G; Huang Ningwu; Agrawal Vishal; Mendonça Berenice B; Bachega Tania A S S; Miller Walter L
Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 2009;94(1):89-95.
2008: Agrawal Vishal; Huang Ningwu; Miller Walter L
Pharmacogenetics of P450 oxidoreductase: effect of sequence variants on activities of CYP1A2 and CYP2C19.
Pharmacogenetics and genomics 2008;18(7):569-76.
2008: Gomes Larissa G; Huang Ningwu; Agrawal Vishal; Mendonça Berenice B; Bachega Tania A S S; Miller Walter L
The common P450 oxidoreductase variant A503V is not a modifier gene for 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 2008;93(7):2913-6.
2008: Bremer Andrew A; Miller Walter L
The serine phosphorylation hypothesis of polycystic ovary syndrome: a unifying mechanism for hyperandrogenemia and insulin resistance.
Fertility and sterility 2008;89(5):1039-48.
2008: Tee Meng Kian; Dong Qing; Miller Walter L
Pathways leading to phosphorylation of p450c17 and to the posttranslational regulation of androgen biosynthesis.
Endocrinology 2008;149(5):2667-77.
2008: Kim Chan Jong; Lin Lin; Huang Ningwu; Quigley Charmian A; AvRuskin Theodore W; Achermann John C; Miller Walter L
Severe combined adrenal and gonadal deficiency caused by novel mutations in the cholesterol side chain cleavage enzyme, P450scc.
The Journal of clinical endocrinology and metabolism 2008;93(3):696-702.
2008: Huang Ningwu; Agrawal Vishal; Giacomini Kathleen M; Miller Walter L
Genetics of P450 oxidoreductase: sequence variation in 842 individuals of four ethnicities and activities of 15 missense mutations.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1733-8.
2008: Miller Walter L
Steroidogenic enzymes.
Endocrine development 2008;13():1-18.
2007: Kim Chan Jong; Kaplan Larry E; Perwad Farzana; Huang Ningwu; Sharma Amita; Choi Yong; Miller Walter L; Portale Anthony A
Vitamin D 1alpha-hydroxylase gene mutations in patients with 1alpha-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 2007;92(8):3177-82.
2007: Miller Walter L
Steroidogenic acute regulatory protein (StAR), a novel mitochondrial cholesterol transporter.
Biochimica et biophysica acta 2007;1771(6):663-76.
2007: Baker Bo Y; Epand Raquel F; Epand Richard M; Miller Walter L
Cholesterol binding does not predict activity of the steroidogenic acute regulatory protein, StAR.
The Journal of biological chemistry 2007;282(14):10223-32.
2007: Miller Walter L
StAR search--what we know about how the steroidogenic acute regulatory protein mediates mitochondrial cholesterol import.
Molecular endocrinology (Baltimore, Md.) 2007;21(3):589-601.
2007: Miller Walter L
Mechanism of StAR's regulation of mitochondrial cholesterol import.
Molecular and cellular endocrinology 2007;265-266():46-50.
2006: Baker Bo Y; Lin Lin; Kim Chan J; Raza Jamal; Smith Claire P; Miller Walter L; Achermann John C
Nonclassic congenital lipoid adrenal hyperplasia: a new disorder of the steroidogenic acute regulatory protein with very late presentation and normal male genitalia.
The Journal of clinical endocrinology and metabolism 2006;91(12):4781-5.
2005: Miller Walter L; Huang Ningwu; Pandey Amit V; Flück Christa E; Agrawal Vishal
P450 oxidoreductase deficiency: a new disorder of steroidogenesis.
Annals of the New York Academy of Sciences 2005;1061():100-8.
2005: Baker Bo Y; Yaworsky Dustin C; Miller Walter L
A pH-dependent molten globule transition is required for activity of the steroidogenic acute regulatory protein, StAR.
The Journal of biological chemistry 2005;280(50):41753-60.
2005: Huang Ningwu; Dardis Andrea; Miller Walter L
Regulation of cytochrome b5 gene transcription by Sp3, GATA-6, and steroidogenic factor 1 in human adrenal NCI-H295A cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(8):2020-34.
2005: Miller Walter L
Minireview: regulation of steroidogenesis by electron transfer.
Endocrinology 2005;146(6):2544-50.
2005: Feldman Brian J; Rosenthal Stephen M; Vargas Gabriel A; Fenwick Raymond G; Huang Eric A; Matsuda-Abedini Mina; Lustig Robert H; Mathias Robert S; Portale Anthony A; Miller Walter L; Gitelman Stephen E
Nephrogenic syndrome of inappropriate antidiuresis.
The New England journal of medicine 2005;352(18):1884-90.
2005: Huang Ningwu; Pandey Amit V; Agrawal Vishal; Reardon William; Lapunzina Pablo D; Mowat David; Jabs Ethylin Wang; Van Vliet Guy; Sack Joseph; Flück Christa E; Miller Walter L
Diversity and function of mutations in p450 oxidoreductase in patients with Antley-Bixler syndrome and disordered steroidogenesis.
American journal of human genetics 2005;76(5):729-49.
2005: Pandey Amit V; Miller Walter L
Regulation of 17,20 lyase activity by cytochrome b5 and by serine phosphorylation of P450c17.
The Journal of biological chemistry 2005;280(14):13265-71.
2005: Flück Christa E; Yaworsky Dustin C; Miller Walter L
Effects of anticonvulsants on human p450c17 (17alpha-hydroxylase/17,20 lyase) and 3beta-hydroxysteroid dehydrogenase type 2.
Epilepsia 2005;46(3):444-8.
2005: Chen Xin; Baker Bo Y; Abduljabbar Mohammad A; Miller Walter L
A genetic isolate of congenital lipoid adrenal hyperplasia with atypical clinical findings.
The Journal of clinical endocrinology and metabolism 2005;90(2):835-40.
2005: Hauet Thierry; Yao Zhi-Xing; Bose Himangshu S; Wall Christopher T; Han Zeqiu; Li Wenping; Hales Dale B; Miller Walter L; Culty Martine; Papadopoulos Vassilios
Peripheral-type benzodiazepine receptor-mediated action of steroidogenic acute regulatory protein on cholesterol entry into leydig cell mitochondria.
Molecular endocrinology (Baltimore, Md.) 2005;19(2):540-54.
2005: Huang Ningwu; Miller Walter L
LBP proteins modulate SF1-independent expression of P450scc in human placental JEG-3 cells.
Molecular endocrinology (Baltimore, Md.) 2005;19(2):409-20.
2005: Yaworsky Dustin C; Baker Bo Y; Bose Himangshu S; Best Katrina B; Jensen Lauren B; Bell John D; Baldwin Michael A; Miller Walter L
pH-dependent Interactions of the carboxyl-terminal helix of steroidogenic acute regulatory protein with synthetic membranes.
The Journal of biological chemistry 2005;280(3):2045-54.
2005: Miller Walter L
Disorders of androgen synthesis--from cholesterol to dehydroepiandrosterone.
Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2005;14 Suppl 1():58-68.
2004: Pandey Amit V; Flück Christa E; Huang Ningwu; Tajima Toshihiro; Fujieda Kenji; Miller Walter L
P450 oxidoreductase deficiency: a new disorder of steroidogenesis affecting all microsomal P450 enzymes.
Endocrine research 2004;30(4):881-8.
2004: Miller Walter L; Huang Ningwu; Flück Christa E; Pandey Amit V
P450 oxidoreductase deficiency.
Lancet 2004;364(9446):1663.
2004: Miller Walter L
P450 oxidoreductase deficiency: a new disorder of steroidogenesis with multiple clinical manifestations.
Trends in endocrinology and metabolism: TEM 2004;15(7):311-5.
2004: Gassner Heidi L; Toppari Jorma; Quinteiro González Sofa; Miller Walter L
Near-miss apparent SIDS from adrenal crisis.
The Journal of pediatrics 2004;145(2):178-83.
2004: Holmes Nicholas M; Miller Walter L; Baskin Laurence S
Lack of defects in androgen production in children with hypospadias.
The Journal of clinical endocrinology and metabolism 2004;89(6):2811-6.
2004: Arlt Weibke; Neogi Partha; Gross Coleman; Miller Walter L
Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of PPARgamma agonist activity.
Journal of molecular endocrinology 2004;32(2):425-36.
2004: Tuckey Robert C; Bose Himangshu S; Czerwionka Inez; Miller Walter L
Molten globule structure and steroidogenic activity of N-218 MLN64 in human placental mitochondria.
Endocrinology 2004;145(4):1700-7.
2004: Flück Christa E; Tajima Toshihro; Pandey Amit V; Arlt Wiebke; Okuhara Kouji; Verge Charles F; Jabs Ethylin Wang; Mendonça Berenice B; Fujieda Kenji; Miller Walter L
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome.
Nature genetics 2004;36(3):228-30.
2003: Lin Chin Jia; Dardis Andrea; Wijesuriya Sujeewa D; Abdullah Mohamed A; Casella Samuel J; Miller Walter L
Lack of mutations in CYP2D6 and CYP27 in patients with apparent deficiency of vitamin D 25-hydroxylase.
Molecular genetics and metabolism 2003;80(4):469-72.
2003: Dardis Andrea; Miller Walter L
Dexamethasone does not exert direct intracellular feedback on steroidogenesis in human adrenal NCI-H295A cells.
The Journal of endocrinology 2003;179(1):131-42.
2003: Flück Christa E; Miller Walter L; Auchus Richard J
The 17, 20-lyase activity of cytochrome p450c17 from human fetal testis favors the delta5 steroidogenic pathway.
The Journal of clinical endocrinology and metabolism 2003;88(8):3762-6.
2003: Rao Rekha M; Jo Youngah; Leers-Sucheta Susan; Bose Himangshu S; Miller Walter L; Azhar Salman; Stocco Douglas M
Differential regulation of steroid hormone biosynthesis in R2C and MA-10 Leydig tumor cells: role of SR-B1-mediated selective cholesteryl ester transport.
Biology of reproduction 2003;68(1):114-21.
2003: Pandey Amit V; Mellon Synthia H; Miller Walter L
Protein phosphatase 2A and phosphoprotein SET regulate androgen production by P450c17.
The Journal of biological chemistry 2003;278(5):2837-44.
2003: Miller Walter L; Portale Anthony A
Vitamin D biosynthesis and vitamin D 1 alpha-hydroxylase deficiency.
Endocrine development 2003;6():156-74.
2002: Miller Walter L
Androgen biosynthesis from cholesterol to DHEA.
Molecular and cellular endocrinology 2002;198(1-2):7-14.
2002: Arlt Wiebke; Martens John W M; Song Maengseok; Wang Jonathan T; Auchus Richard J; Miller Walter L
Molecular evolution of adrenarche: structural and functional analysis of p450c17 from four primate species.
Endocrinology 2002;143(12):4665-72.
2002: Tuckey Robert C; Headlam Madeleine J; Bose Himangshu S; Miller Walter L
Transfer of cholesterol between phospholipid vesicles mediated by the steroidogenic acute regulatory protein (StAR).
The Journal of biological chemistry 2002;277(49):47123-8.
2002: Bose Himangshu S; Lingappa Vishwanath R; Miller Walter L
The steroidogenic acute regulatory protein, StAR, works only at the outer mitochondrial membrane.
Endocrine research 2002;28(4):295-308.
2002: Wijesuriya Sujeewa D; Bristow James; Miller Walter L
Localization and analysis of the principal promoter for human tenascin-X.
Genomics 2002;80(4):443-52.
2002: Xie Zhongjian; Munson Scott J; Huang Ningwu; Portale Anthony A; Miller Walter L; Bikle Daniel D
The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes.
The Journal of biological chemistry 2002;277(40):36987-90.
2002: Flück Christa E; Martens John W M; Conte Felix A; Miller Walter L
Clinical, genetic, and functional characterization of adrenocorticotropin receptor mutations using a novel receptor assay.
The Journal of clinical endocrinology and metabolism 2002;87(9):4318-23.
2002: Wang Xuemei; Zhang Martin Y H; Miller Walter L; Portale Anthony A
Novel gene mutations in patients with 1alpha-hydroxylase deficiency that confer partial enzyme activity in vitro.
The Journal of clinical endocrinology and metabolism 2002;87(6):2424-30.
2002: Bose HimangshuS; Lingappa Vishwanath R; Miller Walter L
Rapid regulation of steroidogenesis by mitochondrial protein import.
Nature 2002;417(6884):87-91.
2002: Zhang Martin Y H; Wang Xuemei; Wang Jonathan T; Compagnone Nathalie A; Mellon Synthia H; Olson Jean L; Tenenhouse Harriet S; Miller Walter L; Portale Anthony A
Dietary phosphorus transcriptionally regulates 25-hydroxyvitamin D-1alpha-hydroxylase gene expression in the proximal renal tubule.
Endocrinology 2002;143(2):587-95.
2001: Lin C J; Martens J W; Miller W L
NF-1C, Sp1, and Sp3 are essential for transcription of the human gene for P450c17 (steroid 17alpha-hydroxylase/17,20 lyase) in human adrenal NCI-H295A cells.
Molecular endocrinology (Baltimore, Md.) 2001;15(8):1277-93.
2001: Huang M C; Miller W L
Creation and activity of COS-1 cells stably expressing the F2 fusion of the human cholesterol side-chain cleavage enzyme system.
Endocrinology 2001;142(6):2569-76.
2001: Arlt W; Auchus R J; Miller W L
Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3beta -hydroxysteroid dehydrogenase.
The Journal of biological chemistry 2001;276(20):16767-71.
2001: Miller W L; Portale A A
Genetics of vitamin D biosynthesis and its disorders.
Best practice & research. Clinical endocrinology & metabolism 2001;15(1):95-109.
2000: Auchus R J; Worthy K; Geller D H; Miller W L
Probing structural and functional domains of human P450c17.
Endocrine research 2000;26(4):695-703.
2000: Bose H S; Baldwin M A; Miller W L
Evidence that StAR and MLN64 act on the outer mitochondrial membrane as molten globules.
Endocrine research 2000;26(4):629-37.
2000: Martens J W; Geller D H; Arlt W; Auchus R J; Ossovskaya V S; Rodriguez H; Dunaif A; Miller W L
Enzymatic activities of P450c17 stably expressed in fibroblasts from patients with the polycystic ovary syndrome.
The Journal of clinical endocrinology and metabolism 2000;85(11):4338-46.
2000: Bose H S; Sato S; Aisenberg J; Shalev S A; Matsuo N; Miller W L
Mutations in the steroidogenic acute regulatory protein (StAR) in six patients with congenital lipoid adrenal hyperplasia.
The Journal of clinical endocrinology and metabolism 2000;85(10):3636-9.
2000: Bose H S; Whittal R M; Huang M C; Baldwin M A; Miller W L
N-218 MLN64, a protein with StAR-like steroidogenic activity, is folded and cleaved similarly to StAR.
Biochemistry 2000;39(38):11722-31.
2000: Portale A A; Miller W L
Human 25-hydroxyvitamin D-1alpha-hydroxylase: cloning, mutations, and gene expression.
Pediatric nephrology (Berlin, Germany) 2000;14(7):620-5.
2000: Huang N; Miller W L
Cloning of factors related to HIV-inducible LBP proteins that regulate steroidogenic factor-1-independent human placental transcription of the cholesterol side-chain cleavage enzyme, P450scc.
The Journal of biological chemistry 2000;275(4):2852-8.
1999: Miller W L
The molecular basis of premature adrenarche: an hypothesis.
Acta paediatrica (Oslo, Norway : 1992). Supplement 1999;88(433):60-6.
1999: Miller W L; Portale A A
Genetic disorders of vitamin D biosynthesis.
Endocrinology and metabolism clinics of North America 1999;28(4):825-40, x.
1999: Wijesuriya S D; Zhang G; Dardis A; Miller W L
Transcriptional regulatory elements of the human gene for cytochrome P450c21 (steroid 21-hydroxylase) lie within intron 35 of the linked C4B gene.
The Journal of biological chemistry 1999;274(53):38097-106.
1999: Miller W L; Portale A A
Genetic causes of rickets.
Current opinion in pediatrics 1999;11(4):333-9.
1999: Miller W L
Dexamethasone treatment of congenital adrenal hyperplasia in utero: an experimental therapy of unproven safety.
The Journal of urology 1999;162(2):537-40.
1999: Auchus R J; Miller W L
Molecular modeling of human P450c17 (17alpha-hydroxylase/17,20-lyase): insights into reaction mechanisms and effects of mutations.
Molecular endocrinology (Baltimore, Md.) 1999;13(7):1169-82.
1999: Bose H S; Whittal R M; Baldwin M A; Miller W L
The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7250-5.
1999: Lee T C; Miller W L; Auchus R J
Medroxyprogesterone acetate and dexamethasone are competitive inhibitors of different human steroidogenic enzymes.
The Journal of clinical endocrinology and metabolism 1999;84(6):2104-10.
1999: Miller W L; Strauss J F
Molecular pathology and mechanism of action of the steroidogenic acute regulatory protein, StAR.
The Journal of steroid biochemistry and molecular biology 1999;69(1-6):131-41.
1999: Geller D H; Auchus R J; Miller W L
P450c17 mutations R347H and R358Q selectively disrupt 17,20-lyase activity by disrupting interactions with P450 oxidoreductase and cytochrome b5.
Molecular endocrinology (Baltimore, Md.) 1999;13(1):167-75.
1999: Miller W L
Congenital adrenal hyperplasia in the adult patient.
Advances in internal medicine 1999;44():155-73.
1998: Miller W L
Steroid hormone biosynthesis and actions in the materno-feto-placental unit.
Clinics in perinatology 1998;25(4):799-817, v.
1998: Wang J T; Lin C J; Burridge S M; Fu G K; Labuda M; Portale A A; Miller W L
Genetics of vitamin D 1alpha-hydroxylase deficiency in 17 families.
American journal of human genetics 1998;63(6):1694-702.
1998: Miller W L
Prenatal treatment of congenital adrenal hyperplasia: a promising experimental therapy of unproven safety.
Trends in endocrinology and metabolism: TEM 1998;9(7):290-3.
1998: Miller W L; Geller D H; Auchus R J
The molecular basis of isolated 17,20 lyase deficiency.
Endocrine research 1998;24(3-4):817-25.
1998: Bose H S; Baldwin M A; Miller W L
Incorrect folding of steroidogenic acute regulatory protein (StAR) in congenital lipoid adrenal hyperplasia.
Biochemistry 1998;37(27):9768-75.
1998: Miller W L
Early steps in androgen biosynthesis: from cholesterol to DHEA.
Baillière's clinical endocrinology and metabolism 1998;12(1):67-81.
1998: Auchus R J; Geller D H; Lee T C; Miller W L
The regulation of human p450c17 activity: relationship to premature adrenarche, insulin resistance and the polycystic ovary syndrome.
Trends in endocrinology and metabolism: TEM 1998;9(2):47-50.
1998: Auchus R J; Lee T C; Miller W L
Cytochrome b5 augments the 17,20-lyase activity of human P450c17 without direct electron transfer.
The Journal of biological chemistry 1998;273(6):3158-65.
1997: Fu G K; Portale A A; Miller W L
Complete structure of the human gene for the vitamin D 1alpha-hydroxylase, P450c1alpha.
DNA and cell biology 1997;16(12):1499-507.
1997: Fu G K; Lin D; Zhang M Y; Bikle D D; Shackleton C H; Miller W L; Portale A A
Cloning of human 25-hydroxyvitamin D-1 alpha-hydroxylase and mutations causing vitamin D-dependent rickets type 1.
Molecular endocrinology (Baltimore, Md.) 1997;11(13):1961-70.
1997: Devoe D J; Miller W L; Conte F A; Kaplan S L; Grumbach M M; Rosenthal S M; Wilson C B; Gitelman S E
Long-term outcome in children and adolescents after transsphenoidal surgery for Cushing's disease.
The Journal of clinical endocrinology and metabolism 1997;82(10):3196-202.
1997: Geller D H; Auchus R J; Mendonça B B; Miller W L
The genetic and functional basis of isolated 17,20-lyase deficiency.
Nature genetics 1997;17(2):201-5.
1997: Burch G H; Gong Y; Liu W; Dettman R W; Curry C J; Smith L; Miller W L; Bristow J
Tenascin-X deficiency is associated with Ehlers-Danlos syndrome.
Nature genetics 1997;17(1):104-8.
1997: Bose H S; Pescovitz O H; Miller W L
Spontaneous feminization in a 46,XX female patient with congenital lipoid adrenal hyperplasia due to a homozygous frameshift mutation in the steroidogenic acute regulatory protein.
The Journal of clinical endocrinology and metabolism 1997;82(5):1511-5.
1997: Miller W L
Pathophysiology, genetics, and treatment of hyperandrogenism.
Pediatric clinics of North America 1997;44(2):375-95.
1997: Rodriguez H; Hum D W; Staels B; Miller W L
Transcription of the human genes for cytochrome P450scc and P450c17 is regulated differently in human adrenal NCI-H295 cells than in mouse adrenal Y1 cells.
The Journal of clinical endocrinology and metabolism 1997;82(2):365-71.
1997: Miller W L; Auchus R J; Geller D H
The regulation of 17,20 lyase activity.
Steroids 1997;62(1):133-42.
1996: Fardella C E; Rodriguez H; Montero J; Zhang G; Vignolo P; Rojas A; Villarroel L; Miller W L
Genetic variation in P450c11AS in Chilean patients with low renin hypertension.
The Journal of clinical endocrinology and metabolism 1996;81(12):4347-51.
1996: Bose H S; Sugawara T; Strauss J F; Miller W L
The pathophysiology and genetics of congenital lipoid adrenal hyperplasia. International Congenital Lipoid Adrenal Hyperplasia Consortium.
The New England journal of medicine 1996;335(25):1870-8.
1996: Speek M; Barry F; Miller W L
Alternate promoters and alternate splicing of human tenascin-X, a gene with 5' and 3' ends buried in other genes.
Human molecular genetics 1996;5(11):1749-58.
1996: Zhang G; Miller W L
The human genome contains only two CYP11B (P450c11) genes.
The Journal of clinical endocrinology and metabolism 1996;81(9):3254-6.
1996: Fardella C E; Hum D W; Rodriguez H; Zhang G; Barry F L; Ilicki A; Bloch C A; Miller W L
Gene conversion in the CYP11B2 gene encoding P450c11AS is associated with, but does not cause, the syndrome of corticosterone methyloxidase II deficiency.
The Journal of clinical endocrinology and metabolism 1996;81(1):321-6.
1995: Tee M K; Lin D; Sugawara T; Holt J A; Guiguen Y; Buckingham B; Strauss J F; Miller W L
T-->A transversion 11 bp from a splice acceptor site in the human gene for steroidogenic acute regulatory protein causes congenital lipoid adrenal hyperplasia.
Human molecular genetics 1995;4(12):2299-305.
1995: Speek M; Miller W L
Hybridization of the complementary mRNAs for P450c21 (steroid 21-hydroxylase) and tenascin-X is prevented by sequence-specific binding of nuclear proteins.
Molecular endocrinology (Baltimore, Md.) 1995;9(12):1655-65.
1995: Miller W L
Mitochondrial specificity of the early steps in steroidogenesis.
The Journal of steroid biochemistry and molecular biology 1995;55(5-6):607-16.
1995: Tee M K; Babalola G O; Aza-Blanc P; Speek M; Gitelman S E; Miller W L
A promoter within intron 35 of the human C4A gene initiates abundant adrenal-specific transcription of a 1 kb RNA: location of a cryptic CYP21 promoter element?
Human molecular genetics 1995;4(11):2109-16.
1995: Zhang G; Rodriguez H; Fardella C E; Harris D A; Miller W L
Mutation T318M in the CYP11B2 gene encoding P450c11AS (aldosterone synthase) causes corticosterone methyl oxidase II deficiency.
American journal of human genetics 1995;57(5):1037-43.
1995: Zhang L H; Rodriguez H; Ohno S; Miller W L
Serine phosphorylation of human P450c17 increases 17,20-lyase activity: implications for adrenarche and the polycystic ovary syndrome.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(23):10619-23.
1995: Tee M K; Thomson A A; Bristow J; Miller W L
Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X.
Genomics 1995;28(2):171-8.
1995: Hum D W; Aza-Blanc P; Miller W L
Characterization of placental transcriptional activation of the human gene for P450scc.
DNA and cell biology 1995;14(5):451-63.
1995: Wilks A; Black S M; Miller W L; Ortiz de Montellano P R
Expression and characterization of truncated human heme oxygenase (hHO-1) and a fusion protein of hHO-1 with human cytochrome P450 reductase.
Biochemistry 1995;34(13):4421-7.
1995: Lin D; Sugawara T; Strauss J F; Clark B J; Stocco D M; Saenger P; Rogol A; Miller W L
Role of steroidogenic acute regulatory protein in adrenal and gonadal steroidogenesis.
Science (New York, N.Y.) 1995;267(5205):1828-31.
1995: Fardella C E; Rodriguez H; Hum D W; Mellon S H; Miller W L
Artificial mutations in P450c11AS (aldosterone synthase) can increase enzymatic activity: a model for low-renin hypertension?
The Journal of clinical endocrinology and metabolism 1995;80(3):1040-3.
1994: Black S M; Harikrishna J A; Szklarz G D; Miller W L
The mitochondrial environment is required for activity of the cholesterol side-chain cleavage enzyme, cytochrome P450scc.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7247-51.
1994: Fardella C E; Hum D W; Homoki J; Miller W L
Point mutation of Arg440 to His in cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 1994;79(1):160-4.
1994: Lin D; Zhang L H; Chiao E; Miller W L
Modeling and mutagenesis of the active site of human P450c17.
Molecular endocrinology (Baltimore, Md.) 1994;8(3):392-402.
1994: Miller W L
Clinical review 54: Genetics, diagnosis, and management of 21-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 1994;78(2):241-6.
1994: Mellon S H; Miller W L; Bair S R; Moore C C; Vigne J L; Weiner R I
Steroidogenic adrenocortical cell lines produced by genetically targeted tumorigenesis in transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1994;8(1):97-108.
1993: Lin D; Chang Y J; Strauss J F; Miller W L
The human peripheral benzodiazepine receptor gene: cloning and characterization of alternative splicing in normal tissues and in a patient with congenital lipoid adrenal hyperplasia.
Genomics 1993;18(3):643-50.
1993: Fardella C E; Zhang L H; Mahachoklertwattana P; Lin D; Miller W L
Deletion of amino acids Asp487-Ser488-Phe489 in human cytochrome P450c17 causes severe 17 alpha-hydroxylase deficiency.
The Journal of clinical endocrinology and metabolism 1993;77(2):489-93.
1993: Moore C C; Mellon S H; Murai J; Siiteri P K; Miller W L
Structure and function of the hepatic form of 11 beta-hydroxysteroid dehydrogenase in the squirrel monkey, an animal model of glucocorticoid resistance.
Endocrinology 1993;133(1):368-75.
1993: Bristow J; Tee M K; Gitelman S E; Mellon S H; Miller W L
Tenascin-X: a novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B.
The Journal of cell biology 1993;122(1):265-78.
1993: Harikrishna J A; Black S M; Szklarz G D; Miller W L
Construction and function of fusion enzymes of the human cytochrome P450scc system.
DNA and cell biology 1993;12(5):371-9.
1993: Lin D; Black S M; Nagahama Y; Miller W L
Steroid 17 alpha-hydroxylase and 17,20-lyase activities of P450c17: contributions of serine106 and P450 reductase.
Endocrinology 1993;132(6):2498-506.
1993: Bristow J; Gitelman S E; Tee M K; Staels B; Miller W L
Abundant adrenal-specific transcription of the human P450c21A "pseudogene".
The Journal of biological chemistry 1993;268(17):12919-24.
1993: Saenger P; Lin D; Gitelman S E; Miller W L
Congenital lipoid adrenal hyperplasia--genes for P450scc, side chain cleavage enzyme, are normal.
The Journal of steroid biochemistry and molecular biology 1993;45(1-3):87-97.
1993: Staels B; Hum D W; Miller W L
Regulation of steroidogenesis in NCI-H295 cells: a cellular model of the human fetal adrenal.
Molecular endocrinology (Baltimore, Md.) 1993;7(3):423-33.
1993: Hum D W; Miller W L
Transcriptional regulation of human genes for steroidogenic enzymes.
Clinical chemistry 1993;39(2):333-40.
1993: Black S M; Szklarz G D; Harikrishna J A; Lin D; Wolf C R; Miller W L
Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells.
Endocrinology 1993;132(2):539-45.
1993: Hum D W; Staels B; Black S M; Miller W L
Basal transcriptional activity and cyclic adenosine 3',5'-monophosphate responsiveness of the human cytochrome P450scc promoter transfected into MA-10 Leydig cells.
Endocrinology 1993;132(2):546-52.
1992: Brentano S T; Miller W L
Regulation of human cytochrome P450scc and adrenodoxin messenger ribonucleic acids in JEG-3 cytotrophoblast cells.
Endocrinology 1992;131(6):3010-8.
1992: Moore C C; Hum D W; Miller W L
Identification of positive and negative placenta-specific basal elements and a cyclic adenosine 3',5'-monophosphate response element in the human gene for P450scc.
Molecular endocrinology (Baltimore, Md.) 1992;6(12):2045-58.
1992: Gitelman S E; Bristow J; Miller W L
Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus.
Molecular and cellular biology 1992;12(7):3313-4.
1992: Gitelman S E; Bristow J; Miller W L
Mechanism and consequences of the duplication of the human C4/P450c21/gene X locus.
Molecular and cellular biology 1992;12(5):2124-34.
1992: Brentano S T; Black S M; Lin D; Miller W L
cAMP post-transcriptionally diminishes the abundance of adrenodoxin reductase mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4099-103.
1991: Miller W L
Congenital adrenal hyperplasias.
Endocrinology and metabolism clinics of North America 1991;20(4):721-49.
1991: Lin D; Gitelman S E; Saenger P; Miller W L
Normal genes for the cholesterol side chain cleavage enzyme, P450scc, in congenital lipoid adrenal hyperplasia.
The Journal of clinical investigation 1991;88(6):1955-62.
1991: Lin D; Harikrishna J A; Moore C C; Jones K L; Miller W L
Missense mutation serine106----proline causes 17 alpha-hydroxylase deficiency.
The Journal of biological chemistry 1991;266(24):15992-8.
1991: Mellon S H; Shively J E; Miller W L
Human proopiomelanocortin-(79-96), a proposed androgen stimulatory hormone, does not affect steroidogenesis in cultured human fetal adrenal cells.
The Journal of clinical endocrinology and metabolism 1991;72(1):19-22.
1991: Moore C C; Miller W L
The role of transcriptional regulation in steroid hormone biosynthesis.
The Journal of steroid biochemistry and molecular biology 1991;40(4-6):517-25.
1990: Townsend S F; Dallman M F; Miller W L
Rat insulin-like growth factor-I and -II mRNAs are unchanged during compensatory adrenal growth but decrease during ACTH-induced adrenal growth.
The Journal of biological chemistry 1990;265(36):22117-22.
1990: Brentano S T; Picado-Leonard J; Mellon S H; Moore C C; Miller W L
Tissue-specific, cyclic adenosine 3',5'-monophosphate-induced, and phorbol ester-repressed transcription from the human P450c17 promoter in mouse cells.
Molecular endocrinology (Baltimore, Md.) 1990;4(12):1972-9.
1990: Lin D; Shi Y F; Miller W L
Cloning and sequence of the human adrenodoxin reductase gene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8516-20.
1990: Moore C C; Brentano S T; Miller W L
Human P450scc gene transcription is induced by cyclic AMP and repressed by 12-O-tetradecanoylphorbol-13-acetate and A23187 through independent cis elements.
Molecular and cellular biology 1990;10(11):6013-23.
1990: Miller W L
Immunoassays for human müllerian inhibitory factor (MIF): new insights into the physiology of MIF.
The Journal of clinical endocrinology and metabolism 1990;70(1):8-10.
1989: Tremblay Y; Ringler G E; Morel Y; Mohandas T K; Labrie F; Strauss J F; Miller W L
Regulation of the gene for estrogenic 17-ketosteroid reductase lying on chromosome 17cen----q25.
The Journal of biological chemistry 1989;264(34):20458-62.
1989: Solish S B; Goldsmith M A; Voutilainen R; Miller W L
Molecular characterization of a Leydig cell tumor presenting as congenital adrenal hyperplasia.
The Journal of clinical endocrinology and metabolism 1989;69(6):1148-52.
1989: Mellon S H; Miller W L
Extraadrenal steroid 21-hydroxylation is not mediated by P450c21.
The Journal of clinical investigation 1989;84(5):1497-502.
1989: Morel Y; Bristow J; Gitelman S E; Miller W L
Transcript encoded on the opposite strand of the human steroid 21-hydroxylase/complement component C4 gene locus.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(17):6582-6.
1989: Silverman B L; Bettendorf M; Kaplan S L; Grumbach M M; Miller W L
Regulation of growth hormone (GH) secretion by GH-releasing factor, somatostatin, and insulin-like growth factor I in ovine fetal and neonatal pituitary cells in vitro.
Endocrinology 1989;124(1):84-9.
1989: Miller W L; Morel Y
The molecular genetics of 21-hydroxylase deficiency.
Annual review of genetics 1989;23():371-93.
1989: Miller W L
Regulation of mRNAs for human steroidogenic enzymes.
Endocrine research 1989;15(1-2):1-16.
1988: Picado-Leonard J; Miller W L
Homologous sequences in steroidogenic enzymes, steroid receptors and a steroid binding protein suggest a consensus steroid-binding sequence.
Molecular endocrinology (Baltimore, Md.) 1988;2(11):1145-50.
1988: Chang C Y; Wu D A; Lai C C; Miller W L; Chung B C
Cloning and structure of the human adrenodoxin gene.
DNA (Mary Ann Liebert, Inc.) 1988;7(9):609-15.
1988: Solish S B; Picado-Leonard J; Morel Y; Kuhn R W; Mohandas T K; Hanukoglu I; Miller W L
Human adrenodoxin reductase: two mRNAs encoded by a single gene on chromosome 17cen----q25 are expressed in steroidogenic tissues.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(19):7104-8.
1988: Morel Y; Picado-Leonard J; Wu D A; Chang C Y; Mohandas T K; Chung B C; Miller W L
Assignment of the functional gene for human adrenodoxin to chromosome 11q13----qter and of adrenodoxin pseudogenes to chromosome 20cen----q13.1.
American journal of human genetics 1988;43(1):52-9.
1988: Silverman B L; Kaplan S L; Grumbach M M; Miller W L
Hormonal regulation of growth hormone secretion and messenger ribonucleic acid accumulation in cultured bovine pituitary cells.
Endocrinology 1988;122(4):1236-41.
1988: Picado-Leonard J; Voutilainen R; Kao L C; Chung B C; Strauss J F; Miller W L
Human adrenodoxin: cloning of three cDNAs and cycloheximide enhancement in JEG-3 cells.
The Journal of biological chemistry 1988;263(7):3240-4.
1988: Voutilainen R; Picado-Leonard J; DiBlasio A M; Miller W L
Hormonal and developmental regulation of adrenodoxin messenger ribonucleic acid in steroidogenic tissues.
The Journal of clinical endocrinology and metabolism 1988;66(2):383-8.
1988: Voutilainen R; Miller W L
Developmental and hormonal regulation of mRNAs for insulin-like growth factor II and steroidogenic enzymes in human fetal adrenals and gonads.
DNA (Mary Ann Liebert, Inc.) 1988;7(1):9-15.
1988: Miller W L
Gene conversions, deletions, and polymorphisms in congenital adrenal hyperplasia.
American journal of human genetics 1988;42(1):4-7.
1987: Picado-Leonard J; Miller W L
Cloning and sequence of the human gene for P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): similarity with the gene for P450c21.
DNA (Mary Ann Liebert, Inc.) 1987;6(5):439-48.
1987: Voutilainen R; Miller W L
Human müllerian inhibitory factor messenger ribonucleic acid is hormonally regulated in the fetal testis and in adult granulosa cells.
Molecular endocrinology (Baltimore, Md.) 1987;1(9):604-8.
1987: Matteson K J; Phillips J A; Miller W L; Chung B C; Orlando P J; Frisch H; Ferrandez A; Burr I M
P450XXI (steroid 21-hydroxylase) gene deletions are not found in family studies of congenital adrenal hyperplasia.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(16):5858-62.
1987: Chung B C; Picado-Leonard J; Haniu M; Bienkowski M; Hall P F; Shively J E; Miller W L
Cytochrome P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase): cloning of human adrenal and testis cDNAs indicates the same gene is expressed in both tissues.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(2):407-11.
1987: Miller W L
Structure of genes encoding steroidogenic enzymes.
Journal of steroid biochemistry 1987;27(4-6):759-66.
1987: Miller W L
Recombinant DNA technology: a fundamental tool for studying development.
Mead Johnson Symposium on Perinatal and Developmental Medicine 1987;(29):27-34.
1986: Chung B C; Matteson K J; Voutilainen R; Mohandas T K; Miller W L
Human cholesterol side-chain cleavage enzyme, P450scc: cDNA cloning, assignment of the gene to chromosome 15, and expression in the placenta.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(23):8962-6.
1986: Matteson K J; Picado-Leonard J; Chung B C; Mohandas T K; Miller W L
Assignment of the gene for adrenal P450c17 (steroid 17 alpha-hydroxylase/17,20 lyase) to human chromosome 10.
The Journal of clinical endocrinology and metabolism 1986;63(3):789-91.
1986: Voutilainen R; Tapanainen J; Chung B C; Matteson K J; Miller W L
Hormonal regulation of P450scc (20,22-desmolase) and P450c17 (17 alpha-hydroxylase/17,20-lyase) in cultured human granulosa cells.
The Journal of clinical endocrinology and metabolism 1986;63(1):202-7.
1986: Chung B C; Matteson K J; Miller W L
Structure of a bovine gene for P-450c21 (steroid 21-hydroxylase) defines a novel cytochrome P-450 gene family.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4243-7.
1986: Matteson K J; Chung B C; Urdea M S; Miller W L
Study of cholesterol side-chain cleavage (20,22 desmolase) deficiency causing congenital lipoid adrenal hyperplasia using bovine-sequence P450scc oligodeoxyribonucleotide probes.
Endocrinology 1986;118(4):1296-305.
1985: Chung B C; Matteson K J; Miller W L
Cloning and characterization of the bovine gene for steroid 21-hydroxylase (P-450c21).
DNA (Mary Ann Liebert, Inc.) 1985;4(3):211-9.
1985: Chung B C; Matteson K J; Morin J E; Mellon S H; Miller W L
An approach to the molecular biology of congenital adrenal hyperplasia.
Annals of the New York Academy of Sciences 1985;458():238-51.

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