FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Todd Miller

Research Profile

Phenomena

Phosphorylation

Genes & Molecular Sequences

Amino Acid Sequences

Chemicals & Drugs

Concepts & Ideas

Co-author Network

Publications

TOP 3
Kira P Schultheiss; Markus Seeliger; Michael Tong; Barbara P Craddock; W Todd Miller
Metazoan-like signaling in a unicellular receptor tyrosine kinase.
Barbara P Craddock; W Todd Miller
Effects of somatic mutations in the C-terminus of insulin-like growth factor 1 receptor on activity and signaling.
Victoria Prieto-Echagüe; W Todd Miller
Regulation of ack-family nonreceptor tyrosine kinases.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Todd Miller (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Kira P Schultheiss; Markus Seeliger; Michael Tong; Barbara P Craddock; W Todd Miller
Metazoan-like signaling in a unicellular receptor tyrosine kinase.
BMC biochemistry 2013;14():4.
2012: Barbara P Craddock; W Todd Miller
Effects of somatic mutations in the C-terminus of insulin-like growth factor 1 receptor on activity and signaling.
Journal of signal transduction 2012;2012():804801.
2011: Victoria Prieto-Echagüe; W Todd Miller
Regulation of ack-family nonreceptor tyrosine kinases.
Journal of signal transduction 2011;2011():742372.
2011: Victoria Prieto-Echagüe; PM Chan; Barbara P Craddock; Edward Manser; W Todd Miller
PTB domain-directed substrate targeting in a tyrosine kinase from the unicellular choanoflagellate Monosiga brevicollis.
PloS one 2011;6(4):e19296.
2010: Victoria Prieto-Echagüe; Azad Gucwa; Deborah A Brown; W Todd Miller
Regulation of Ack1 localization and activity by the amino-terminal SAM domain.
BMC biochemistry 2010;11():42.
2009: Shalini S Yadav; Brian J Yeh; Barbara P Craddock; Wendell A Lim; W Todd Miller
Reengineering the signaling properties of a Src family kinase.
Biochemistry 2009;48(46):10956-62.
2009: Parag Patwardhan; Kiyotaka Shiba; Chris Gordon; Barbara P Craddock; Minamisawa Tamiko; W Todd Miller
Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs.
ACS chemical biology 2009;4(9):751-8.
2009: Wanqing Li; Suzanne Scarlata; W Todd Miller
Evidence for convergent evolution in the signaling properties of a choanoflagellate tyrosine kinase.
Biochemistry 2009;48(23):5180-6.
2008: Shalini S Yadav; W Todd Miller
The evolutionarily conserved arrangement of domains in SRC family kinases is important for substrate recognition.
Biochemistry 2008;47(41):10871-80.
2008: Wanqing Li; Susan L Young; Nicole King; W Todd Miller
Signaling properties of a non-metazoan Src kinase and the evolutionary history of Src negative regulation.
The Journal of biological chemistry 2008;283(22):15491-501.
2007: Shalini S Yadav; W Todd Miller
Cooperative activation of Src family kinases by SH3 and SH2 ligands.
Cancer letters 2007;257(1):116-23.
2007: Parag Patwardhan; W Todd Miller
Processive phosphorylation: mechanism and biological importance.
Cellular signalling 2007;19(11):2218-26.
2007: Barbara P Craddock; Christopher Cotter; W Todd Miller
Autoinhibition of the insulin-like growth factor I receptor by the juxtamembrane region.
FEBS letters 2007;581(17):3235-40.
2006: Wanqing Li; W Todd Miller
Role of the activation loop tyrosines in regulation of the insulin-like growth factor I receptor-tyrosine kinase.
The Journal of biological chemistry 2006;281(33):23785-91.
2006: Parag Patwardhan; Yongquan Shen; Gary S Goldberg; W Todd Miller
Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth.
The Journal of biological chemistry 2006;281(30):20689-97.
2005: Noriko Yokoyama; Julie Lougheed; W Todd Miller
Phosphorylation of WASP by the Cdc42-associated kinase ACK1: dual hydroxyamino acid specificity in a tyrosine kinase.
The Journal of biological chemistry 2005;280(51):42219-26.
2005: Haoqun Qiu; Francesca Zappacosta; Wenjuan Su; Roland S Annan; W Todd Miller
Interaction between Brk kinase and insulin receptor substrate-4.
Oncogene 2005;24(36):5656-64.
2005: Noriko Yokoyama; Colin D deBakker; Francesca Zappacosta; Michael J Huddleston; Roland S Annan; Kodi S Ravichandran; W Todd Miller
Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.
Biochemistry 2005;44(24):8841-9.
2005: Noriko Yokoyama; Irene Ischenko; Michael J Hayman; W Todd Miller
The C terminus of RON tyrosine kinase plays an autoinhibitory role.
The Journal of biological chemistry 2005;280(10):8893-900.
2004: Wanqing Li; Svetlana Favelyukis; Jie Yang; Yibin Zeng; Jamming Yu; Aleem Gangjee; W Todd Miller
Inhibition of insulin-like growth factor I receptor autophosphorylation by novel 6-5 ring-fused compounds.
Biochemical pharmacology 2004;68(1):145-54.
2004: David B Alexander; Hitoshi Ichikawa; John F Bechberger; Virginijus Valiunas; Misao Ohki; Christian C G Naus; Takehiko Kunimoto; Hiroyuki Tsuda; W Todd Miller; Gary S Goldberg
Normal cells control the growth of neighboring transformed cells independent of gap junctional communication and SRC activity.
Cancer research 2004;64(4):1347-58.
2003: Noriko Yokoyama; W Todd Miller
Biochemical properties of the Cdc42-associated tyrosine kinase ACK1. Substrate specificity, authphosphorylation, and interaction with Hck.
The Journal of biological chemistry 2003;278(48):47713-23.
2003: Gary S Goldberg; David B Alexander; Patricia Pellicena; Zhong-Yin Zhang; Hiroyuki Tsuda; W Todd Miller
Src phosphorylates Cas on tyrosine 253 to promote migration of transformed cells.
The Journal of biological chemistry 2003;278(47):46533-40.
2003: Nikolas von Bubnoff; Darren R Veach; W Todd Miller; Wanqing Li; Jana Sänger; Christian Peschel; William G Bornmann; Bayard Clarkson; Justus Duyster
Inhibition of wild-type and mutant Bcr-Abl by pyrido-pyrimidine-type small molecule kinase inhibitors.
Cancer research 2003;63(19):6395-404.
2003: Noriko Yokoyama; Nancy C Reich; W Todd Miller
Determinants for the interaction between Janus kinase 2 and protein phosphatase 2A.
Archives of biochemistry and biophysics 2003;417(1):87-95.
2003: W Todd Miller
Determinants of substrate recognition in nonreceptor tyrosine kinases.
Accounts of chemical research 2003;36(6):393-400.
2002: Haoqun Qiu; W Todd Miller
Regulation of the nonreceptor tyrosine kinase Brk by autophosphorylation and by autoinhibition.
The Journal of biological chemistry 2002;277(37):34634-41.
2002: Margaret Porter Scott; Francesca Zappacosta; Eun Young Kim; Roland S Annan; W Todd Miller
Identification of novel SH3 domain ligands for the Src family kinase Hck. Wiskott-Aldrich syndrome protein (WASP), WASP-interacting protein (WIP), and ELMO1.
The Journal of biological chemistry 2002;277(31):28238-46.
2002: Bhushan Nagar; William G Bornmann; Patricia Pellicena; Thomas Schindler; Darren R Veach; W Todd Miller; Bayard Clarkson; John Kuriyan
Crystal structures of the kinase domain of c-Abl in complex with the small molecule inhibitors PD173955 and imatinib (STI-571).
Cancer research 2002;62(15):4236-43.
2002: Patricia Pellicena; W Todd Miller
Coupling kinase activation to substrate recognition in SRC-family tyrosine kinases.
Frontiers in bioscience : a journal and virtual library 2002;7():d256-67.
2001: Svetlana Favelyukis; Jeffrey H Till; Stevan Hubbard; W Todd Miller
Structure and autoregulation of the insulin-like growth factor 1 receptor kinase.
Nature structural biology 2001;8(12):1058-63.
2001: M Amoui; B P Craddock; W Todd Miller
Differential phosphorylation of IRS-1 by insulin and insulin-like growth factor I receptors in Chinese hamster ovary cells.
The Journal of endocrinology 2001;171(1):153-62.
2001: Noriko Yokoyama; W Todd Miller
Inhibition of Src by direct interaction with protein phosphatase 2A.
FEBS letters 2001;505(3):460-4.
2001: Noriko Yokoyama; W Todd Miller
Protein phosphatase 2A interacts with the Src kinase substrate p130(CAS).
Oncogene 2001;20(42):6057-65.
2001: Patricia Pellicena; W Todd Miller
Processive phosphorylation of p130Cas by Src depends on SH3-polyproline interactions.
The Journal of biological chemistry 2001;276(30):28190-6.
2001: Noriko Yokoyama; N C Reich; W Todd Miller
Involvement of protein phosphatase 2A in the interleukin-3-stimulated Jak2-Stat5 signaling pathway.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(6):369-78.
2000: M P Scott; W Todd Miller
A peptide model system for processive phosphorylation by Src family kinases.
Biochemistry 2000;39(47):14531-7.
2000: PM Chan; H P Nestler; W Todd Miller
Investigating the substrate specificity of the HER2/Neu tyrosine kinase using peptide libraries.
Cancer letters 2000;160(2):159-69.
2000: M Amoui; W Todd Miller
The substrate specificity of the catalytic domain of Abl plays an important role in directing phosphorylation of the adaptor protein Crk.
Cellular signalling 2000;12(9-10):637-43.
2000: Thomas Schindler; William G Bornmann; Patricia Pellicena; W Todd Miller; Bayard Clarkson; John Kuriyan
Structural mechanism for STI-571 inhibition of abelson tyrosine kinase.
Science (New York, N.Y.) 2000;289(5486):1938-42.
1999: J E Michaels; K Shiba; W Todd Miller
Autonomous folding of a C-terminal inhibitory fragment of Escherichia coli isoleucine-tRNA synthetase.
Biochimica et biophysica acta 1999;1433(1-2):103-9.
1999: Noriko Yokoyama; W Todd Miller
Identification of residues involved in v-Src substrate recognition by site-directed mutagenesis.
FEBS letters 1999;456(3):403-8.
1999: Jeffrey H Till; PM Chan; W Todd Miller
Engineering the substrate specificity of the Abl tyrosine kinase.
The Journal of biological chemistry 1999;274(8):4995-5003.
1998: M LaFevre-Bernt; F Sicheri; A Pico; M Porter; John Kuriyan; W Todd Miller
Intramolecular regulatory interactions in the Src family kinase Hck probed by mutagenesis of a conserved tryptophan residue.
The Journal of biological chemistry 1998;273(48):32129-34.
1998: M LaFevre-Bernt; J D Corbin; S H Francis; W Todd Miller
Phosphorylation and activation of cGMP-dependent protein kinase by Src.
Biochimica et biophysica acta 1998;1386(1):97-105.
1998: Patricia Pellicena; K R Stowell; W Todd Miller
Enhanced phosphorylation of Src family kinase substrates containing SH2 domain binding sites.
The Journal of biological chemistry 1998;273(25):15325-8.
1997: Ismail Moarefi; M LaFevre-Bernt; F Sicheri; Morgan Huse; C H Lee; John Kuriyan; W Todd Miller
Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
Nature 1997;385(6617):650-3.
1996: J E Michaels; P Schimmel; K Shiba; W Todd Miller
Dominant negative inhibition by fragments of a monomeric enzyme.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14452-5.
1996: P Pellicena; Jeffrey D Scholten; K Zimmerman; M Creswell; C C Huang; W Todd Miller
Involvement of the alpha subunit of farnesyl-protein transferase in substrate recognition.
Biochemistry 1996;35(41):13494-500.
1996: P M Chan; Paul R Keller; R W Connors; Wilbur R Leopold; W Todd Miller
Amino-terminal sequence determinants for substrate recognition by platelet-derived growth factor receptor tyrosine kinase.
FEBS letters 1996;394(2):121-5.
1996: B Xu; W Todd Miller
Src homology domains of v-Src stabilize an active conformation of the tyrosine kinase catalytic domain.
Molecular and cellular biochemistry 1996;158(1):57-63.
1996: Zhong-Yin Zhang; A B Walsh; Li Wu; Dennis J McNamara; Ellen M Dobrusin; W Todd Miller
Determinants of substrate recognition in the protein-tyrosine phosphatase, PTP1.
The Journal of biological chemistry 1996;271(10):5386-92.
1995: B Xu; Vincent G Bird; W Todd Miller
Substrate specificities of the insulin and insulin-like growth factor 1 receptor tyrosine kinase catalytic domains.
The Journal of biological chemistry 1995;270(50):29825-30.
1994: J R Gergel; Dennis J McNamara; Ellen M Dobrusin; G Zhu; Alan Saltiel; W Todd Miller
Identification of amino acids in the N-terminal SH2 domain of phospholipase C gamma 1 important in the interaction with epidermal growth factor receptor.
Biochemistry 1994;33(49):14671-8.
1994: P Garcia; S E Shoelson; J S Drew; W Todd Miller
Phosphopeptide occupancy and photoaffinity cross-linking of the v-Src SH2 domain attenuates tyrosine kinase activity.
The Journal of biological chemistry 1994;269(48):30574-9.
1994: J H Till; Roland S Annan; Steve Carr; W Todd Miller
Use of synthetic peptide libraries and phosphopeptide-selective mass spectrometry to probe protein kinase substrate specificity.
The Journal of biological chemistry 1994;269(10):7423-8.
1993: P Garcia; S E Shoelson; ST George; D A Hinds; AR Goldberg; W Todd Miller
Phosphorylation of synthetic peptides containing Tyr-Met-X-Met motifs by nonreceptor tyrosine kinases in vitro.
The Journal of biological chemistry 1993;268(33):25146-51.
1989: C Radziejewski; W Todd Miller; Shahriar Mobashery; A R Goldberg; E T Kaiser
Purification of recombinant pp60v-src protein tyrosine kinase and phosphorylation of peptides with different secondary structure preference.
Biochemistry 1989;28(23):9047-52.
1988: W Todd Miller; E T Kaiser
Probing the peptide binding site of the cAMP-dependent protein kinase by using a peptide-based photoaffinity label.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(15):5429-33.
1987: H N Bramson; Nancy E Thomas; W Todd Miller; D C Fry; A S Mildvan; E T Kaiser
Conformation of Leu-Arg-Arg-Ala-Ser-Leu-Gly bound in the active site of adenosine cyclic 3',5'-phosphate dependent protein kinase.
Biochemistry 1987;26(14):4666-70.
1987: Nancy E Thomas; H N Bramson; W Todd Miller; E T Kaiser
Role of enzyme-peptide substrate backbone hydrogen bonding in determining protein kinase substrate specificities.
Biochemistry 1987;26(14):4461-6.