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E Millerman

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Yuntao Song; SS Bowersox; David T Connor; David J Dooley; Susan M Lotarski; TC Malone; GP Miljanich; E Millerman; Michael F Rafferty; D Rock; Bruce D Roth; J Schmidt; SJ Stoehr; BG Szoke; C Taylor; Mark G Vartanian; Y X Wang
(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; Charles P Taylor; MR Feng; BS Kuo; Susan M Lotarski; GP Miljanich; E Millerman; K M Siebers; BG Szoke
The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia.
Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; K M Siebers; TC Malone; A Chatterjee; MR Feng; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.

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All Publications

2000: Yuntao Song; SS Bowersox; David T Connor; David J Dooley; Susan M Lotarski; TC Malone; GP Miljanich; E Millerman; Michael F Rafferty; D Rock; Bruce D Roth; J Schmidt; SJ Stoehr; BG Szoke; C Taylor; Mark G Vartanian; Y X Wang
(S)-4-Methyl-2-(methylamino)pentanoic acid [4, 4-bis(4-fluorophenyl)butyl]amide hydrochloride, a novel calcium channel antagonist, is efficacious in several animal models of pain.
Journal of medicinal chemistry 2000;43(19):3474-7.
2000: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; Charles P Taylor; MR Feng; BS Kuo; Susan M Lotarski; GP Miljanich; E Millerman; K M Siebers; BG Szoke
The discovery of [1-(4-dimethylamino-benzyl)-piperidin-4-yl]-[4-(3,3-dimethylbutyl)-phen yl]-(3-methyl-but-2-enyl)-amine, an N-type Ca+2 channel blocker with oral activity for analgesia.
Bioorganic & medicinal chemistry 2000;8(6):1203-12.
2000: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; K M Siebers; TC Malone; A Chatterjee; MR Feng; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Neuronal N-type calcium channel blockers: a series of 4-piperidinylaniline analogs with analgesic activity.
Drug design and discovery 2000;17(1):85-93.
2000: Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Structure-activity relationship at the leucine side chain in a series of N,N-dialkyldipeptidyl-amines as N-type calcium channel blockers.
Drug design and discovery 2000;16(4):317-22.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; MR Feng; Susan M Lotarski; DM Rock; M Sinz; SJ Stoehr; Charles P Taylor; Mark L Weber; SS Bowersox; GP Miljanich; E Millerman; Y X Wang; BG Szoke
Synthesis of a series of 4-benzyloxyaniline analogues as neuronal N-type calcium channel blockers with improved anticonvulsant and analgesic properties.
Journal of medicinal chemistry 1999;42(20):4239-49.
1999: Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; Susan M Lotarski; DM Rock; SJ Stoehr; Charles P Taylor; Mark L Weber; GP Miljanich; E Millerman; BG Szoke
Structure-activity relationship at the proximal phenyl group in a series of non-peptidyl N-type calcium channel antagonists.
Bioorganic & medicinal chemistry letters 1999;9(16):2453-8.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; David J Dooley; J J Geer; Susan M Lotarski; GP Miljanich; E Millerman; DM Rock; SJ Stoehr; BG Szoke; Charles P Taylor; Mark G Vartanian
Structure-activity relationship of N-methyl-N-aralkyl-peptidylamines as novel N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(15):2151-6.
1999: Todd R Ryder; Lain-Yen Hu; Michael F Rafferty; E Millerman; BG Szoke; K Tarczy-Hornoch
Multiple parallel synthesis of N,N-dialkyldipeptidylamines as N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(13):1813-8.
1999: Lain-Yen Hu; Todd R Ryder; S S Nikam; E Millerman; BG Szoke; Michael F Rafferty
Synthesis and biological evaluation of substituted 4-(OBz)phenylalanine derivatives as novel N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(8):1121-6.
1999: Lain-Yen Hu; Todd R Ryder; Michael F Rafferty; Wayne L Cody; Susan M Lotarski; GP Miljanich; E Millerman; DM Rock; Yuntao Song; SJ Stoehr; Charles P Taylor; Mark L Weber; BG Szoke; Mark G Vartanian
N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers.
Bioorganic & medicinal chemistry letters 1999;9(6):907-12.