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Hendrik Milting

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Gülsüm Erkilet; Jan Gummert; Frank Kramer; Birte Bohms; Dietmar Böthig; Michiel Morshuis; Daniela Röfe; Cenk Ozpeker; Hendrik Milting
The biomarker plasma galectin-3 in advanced heart failure and survival with mechanical circulatory support devices.
Astrid Kassner; Peter Kolkhof; Michiel Morshuis; Sebastian Schulte Eistrup; Karl Toischer; Getu Abraham; Birte Bohms; Aly El-Banayosy; Jan Gummert; Gerd Hasenfuβ; Hendrik Milting
Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
Aalap Chokshi; Christine S Chung; Konstantinos Drosatos; Ira J Goldberg; Ruiping Ji; Ulrich P Jorde; Tomoko Kato; Raffay Khan; Tuba Khawaja; Ralph Knöll; Donna M Mancini; Hendrik Milting; Yoshifumi Naka; Hiroo Takayama; Shuiqing Yu; Faisal H Cheema; P Christian Schulze
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.

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All Publications

2013: Gülsüm Erkilet; Jan Gummert; Frank Kramer; Birte Bohms; Dietmar Böthig; Michiel Morshuis; Daniela Röfe; Cenk Ozpeker; Hendrik Milting
The biomarker plasma galectin-3 in advanced heart failure and survival with mechanical circulatory support devices.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2013;32(2):221-30.
2012: Astrid Kassner; Peter Kolkhof; Michiel Morshuis; Sebastian Schulte Eistrup; Karl Toischer; Getu Abraham; Birte Bohms; Aly El-Banayosy; Jan Gummert; Gerd Hasenfuβ; Hendrik Milting
Regulation of cyclic adenosine monophosphate release by selective β2-adrenergic receptor stimulation in human terminal failing myocardium before and after ventricular assist device support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012;31(10):1127-35.
2012: Aalap Chokshi; Christine S Chung; Konstantinos Drosatos; Ira J Goldberg; Ruiping Ji; Ulrich P Jorde; Tomoko Kato; Raffay Khan; Tuba Khawaja; Ralph Knöll; Donna M Mancini; Hendrik Milting; Yoshifumi Naka; Hiroo Takayama; Shuiqing Yu; Faisal H Cheema; P Christian Schulze
Ventricular assist device implantation corrects myocardial lipotoxicity, reverses insulin resistance, and normalizes cardiac metabolism in patients with advanced heart failure.
Circulation 2012;125(23):2844-53.
2012: Andreas Brodehl; Mareike Dieding; Azra Fatima; Susan Gayda; Jan Gummert; Per Niklas Hedde; Mike Heilemann; Bärbel Klauke; Gerd Ulrich Nienhaus; Volker Walhorn; Tomo Saric; Dario Anselmetti; Hendrik Milting
Dual color photoactivation localization microscopy of cardiomyopathy-associated desmin mutants.
The Journal of biological chemistry 2012;287(19):16047-57.
2012: J Wohlschläger; T Hager; B Levkau; Hendrik Milting; C Schmid; Jörg Stypmann; Hideo A Baba
[Congestive heart failure: reverse cardiac remodeling mediated by left ventricular assist devices].
Der Pathologe 2012;33(3):175-82.
2012: Raffay S Khan; Ralph Knöll; Donna Mancini; Hendrik Milting; Yoshifumi Naka; Gissette Reyes-Soffer; Faisal H Cheema; Michael Chew; Aalap Chokshi; Collette Harris; Tomoko S Kato; Parvati Singh; Hiroo Takayama; Christina Wu; Shuiqing Yu; P Christian Schulze
Adipose tissue inflammation and adiponectin resistance in patients with advanced heart failure: correction after ventricular assist device implantation.
Circulation. Heart failure 2012;5(3):340-8.
2012: Jeremias Wohlschlaeger; Kurt Werner Schmid; Bodo Levkau; Hendrik Milting; Christof Schmid; Jörg Stypmann; Atsushi Takeda; Nobuakira Takeda; Hideo Andreas Baba
Increase of ABCG2/BCRP+ side population stem cells in myocardium after ventricular unloading.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2012;31(3):318-24.
2012: Anna Gaertner; Stefan Golz; Jan Gummert; Astrid Kassner; Uwe Schulz; Patrick Schwientek; Holger Summer; Peter Ellinghaus; Hendrik Milting
Myocardial transcriptome analysis of human arrhythmogenic right ventricular cardiomyopathy.
Physiological genomics 2012;44(1):99-109.
2012: Arun K Subra; Kevin M Lewis; Hendrik Milting; Ashwin K Muralidharan; MS Nissen; Emiliano J Sanchez; Chulhee Kang
Molecular mechanisms of pharmaceutical drug binding into calsequestrin.
International journal of molecular sciences 2012;13(11):14326-43.
2012: Anna Gaertner; Jan Gummert; Baerbel Klauke; Karsten Niehaus; Gesa Niemann; Ines Stork; Hendrik Milting
In vitro functional analyses of arrhythmogenic right ventricular cardiomyopathy-associated desmoglein-2-missense variations.
PloS one 2012;7(10):e47097.
2011: Peter Milberg; Hendrik Milting; Sigrid Nikol; Nani Osada; Trong Hung Quang; Jörg Stypmann; Johannes Waltenberger; Michael Fehr; Gerrit Frommeyer; Rainer Klocke; Michael Kuhlmann; Günter Breithardt; Kati Dieks; Lars Eckardt
G-CSF therapy reduces myocardial repolarization reserve in the presence of increased arteriogenesis, angiogenesis and connexin 43 expression in an experimental model of pacing-induced heart failure.
Basic research in cardiology 2011;106(6):995-1008.
2011: Stephan Waldmüller; Wolfgang Zeh; Priska Binner; Wulf Blankenfeldt; Jan Börgel; Turgut Brodherr; Anastassia Dermintzoglou; Jeanette Erdmann; Martin Farr; Christian Geier; Götz Gelbrich; Janine Haremza; Beate Jurmann; Markus Loeffler; Bernhard Maisch; Hendrik Milting; Karl Josef Osterziel; Cemil Özcelik; Sabine Pankuweit; Andreas Perrot; Vera Regitz-Zagrosek; Richard Reinhardt; Steffen Scheer; Thomas Scheffold; Jost Schönberger; Norbert Schulze-Waltrup; Heribert Schunkert; Bernd Timmermann; Rolf Wachter
Novel correlations between the genotype and the phenotype of hypertrophic and dilated cardiomyopathy: results from the German Competence Network Heart Failure.
European journal of heart failure 2011;13(11):1185-92.
2011: Frank Kramer; Hendrik Milting
Novel biomarkers in human terminal heart failure and under mechanical circulatory support.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2011;16 Suppl 1():S31-41.
2011: Emiliano J Sanchez; Gerhard R Munske; Angela Criswell; Hendrik Milting; A Keith Dunker; Chulhee Kang
Phosphorylation of human calsequestrin: implications for calcium regulation.
Molecular and cellular biochemistry 2011;353(1-2):195-204.
2010: Baerbel Klauke; Sabine Kossmann; Anna Gaertner; Kristina Brand; Ines Stork; Andreas Brodehl; Mareike Dieding; Volker Walhorn; Dario Anselmetti; Désirée Gerdes; Birte Bohms; Uwe Schulz; Edzard Zu Knyphausen; Matthias Vorgerd; Jan Gummert; Hendrik Milting
De novo desmin-mutation N116S is associated with arrhythmogenic right ventricular cardiomyopathy.
Human molecular genetics 2010;19(23):4595-607.
2010: Chulhee Kang; MS Nissen; Emiliano J Sanchez; Ka-Sum Lam; Hendrik Milting
Potential adverse interaction of human cardiac calsequestrin.
European journal of pharmacology 2010;646(1-3):12-21.
2010: Patrick Schwientek; Peter Ellinghaus; Sonja Steppan; Donatella D'Urso; Michael Seewald; Astrid Kassner; Ramona Cebulla; Sebastian Schulte-Eistrup; Michiel Morshuis; Daniela Röfe; Aly El-Banayosy; Reiner Körfer; Hendrik Milting
Global gene expression analysis in nonfailing and failing myocardium pre- and postpulsatile and nonpulsatile ventricular assist device support.
Physiological genomics 2010;42(3):397-405.
2010: Julia Otten; Peter F.M. van der Ven; Padmanabhan Vakeel; Stefan Eulitz; Gregor Kirfel; Oliver Brandau; Michael Boesl; Jan Schrickel; Markus Linhart; Katrin Hayess; Francisco J Naya; Hendrik Milting; Rainer Meyer; Dieter O Fürst
Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.
Cardiovascular research 2010;85(4):739-50.
2010: Karl Toischer; Stephan Lehnart; Gero Tenderich; Hendrik Milting; Reiner Körfer; Jan Schmitto; Friedrich A Schöndube; Noboru Kaneko; Christopher M Loughrey; Godfrey L Smith; Gerd Hasenfuss; Tim Seidler
K201 improves aspects of the contractile performance of human failing myocardium via reduction in Ca2+ leak from the sarcoplasmic reticulum.
Basic research in cardiology 2010;105(2):279-87.
2010: Jeremias Wohlschlaeger; Stephan Urs Sixt; Tatjana Stoeppler; Klaus J Schmitz; Bodo Levkau; Konstantinos Tsagakis; Christian Vahlhaus; Christof Schmid; Jürgen Peters; Kurt Werner Schmid; Hendrik Milting; Hideo Andreas Baba
Ventricular unloading is associated with increased 20s proteasome protein expression in the myocardium.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2010;29(1):125-32.
2009: Thomas Gawlowski; Bernd Stratmann; I Stork; B Engelbrecht; A Brodehl; K Niehaus; R Körfer; Diethelm Tschoepe; Hendrik Milting
Heat shock protein 27 modification is increased in the human diabetic failing heart.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2009;41(8):594-9.
2009: Michael J Seewald; Peter Ellinghaus; Astrid Kassner; Ines Stork; Martina Barg; Sylvia Niebrügge; Stefan Golz; Holger Summer; Robert Zweigerdt; Eva-Maria Schräder; Samantha Feicht; Kornelia Jaquet; Stephanie Reis; Reiner Körfer; Hendrik Milting
Genomic profiling of developing cardiomyocytes from recombinant murine embryonic stem cells reveals regulation of transcription factor clusters.
Physiological genomics 2009;38(1):7-15.
2009: Stefan Schäfer; Peter Ellinghaus; Wiebke Janssen; Frank Kramer; Klemens Lustig; Hendrik Milting; Raimund Kast; Martina Klein
Chronic inhibition of phosphodiesterase 5 does not prevent pressure-overload-induced right-ventricular remodelling.
Cardiovascular research 2009;82(1):30-9.
2008: Martina Klein; Ralph Theo Schermuly; Peter Ellinghaus; Hendrik Milting; Bernd Riedl; Sevdalina Nikolova; Soni S Pullamsetti; Norbert Weissmann; Eva Dony; Rajkumar Savai; Hossein A Ghofrani; Friedrich Grimminger; Andreas E Busch; Stefan Schäfer
Combined tyrosine and serine/threonine kinase inhibition by sorafenib prevents progression of experimental pulmonary hypertension and myocardial remodeling.
Circulation 2008;118(20):2081-90.
2008: Hendrik Milting; Baerbel Klauke
Molecular genetics of arrhythmogenic right ventricular dysplasia/cardiomyopathy.
Nature clinical practice. Cardiovascular medicine 2008;5(10):E1; author reply E2.
2008: Bärbel Klauke; Andreas Wirth; Armin Zittermann; Birte Bohms; Gero Tenderich; Reiner Körfer; Hendrik Milting
No association between single nucleotide polymorphisms and the development of nephrotoxicity after orthotopic heart transplantation.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008;27(7):741-5.
2008: Hendrik Milting; Peter Ellinghaus; Michael Seewald; Hamdin Cakar; Birte Bohms; Astrid Kassner; Reiner Körfer; Martina Klein; Thomas Krahn; Lothar Kruska; Aly El-Banayosy; Frank Kramer
Plasma biomarkers of myocardial fibrosis and remodeling in terminal heart failure patients supported by mechanical circulatory support devices.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008;27(6):589-96.
2008: Jeremias Wohlschlaeger; Moritz von Winterfeld; Hendrik Milting; Aly El-Banayosy; Klaus J Schmitz; Atsushi Takeda; Nobuakira Takeda; Petra Azhari; Christof Schmid; Christian August; Kurt W Schmid; Hideo Andreas Baba
Decreased myocardial chromogranin a expression and colocalization with brain natriuretic peptide during reverse cardiac remodeling after ventricular unloading.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2008;27(4):442-9.
2008: Sergiu Scobioala; Rainer Klocke; Michael T Kuhlmann; Wen Tian; Lekbira Hasib; Hendrik Milting; Simone Koenig; Matthias Stelljes; Aly El-Banayosy; Gero Tenderich; Guenter Michel; Guenter Breithardt; Sigrid Nikol
Up-regulation of nestin in the infarcted myocardium potentially indicates differentiation of resident cardiac stem cells into various lineages including cardiomyocytes.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(4):1021-31.
2008: Katja Gehmlich; Christian Geier; Hendrik Milting; Dieter Fürst; Elisabeth Ehler
Back to square one: what do we know about the functions of muscle LIM protein in the heart?
Journal of muscle research and cell motility 2008;29(6-8):155-8.
2007: Eunjung Kim; Buhyun Youn; Lenord Kemper; Cait Campbell; Hendrik Milting; Magdolna Varsanyi; ChulHee Kang
Characterization of human cardiac calsequestrin and its deleterious mutants.
Journal of molecular biology 2007;373(4):1047-57.
2007: Christian Prante; Hendrik Milting; Astrid Kassner; Martin Farr; Michael Ambrosius; Sylvia Schön; Daniela G Seidler; Aly El Banayosy; Reiner Körfer; Joachim Kuhn; Knut Kleesiek; Christian Götting
Transforming growth factor beta1-regulated xylosyltransferase I activity in human cardiac fibroblasts and its impact for myocardial remodeling.
The Journal of biological chemistry 2007;282(36):26441-9.
2007: Katja Gehmlich; Nikos Pinotsis; Katrin Hayess; Peter F.M. van der Ven; Hendrik Milting; Aly El-Banayosy; Reiner Körfer; Matthias Wilmanns; Elisabeth Ehler; Dieter O Fürst
Paxillin and ponsin interact in nascent costameres of muscle cells.
Journal of molecular biology 2007;369(3):665-82.
2006: Hendrik Milting; Christian Scholz; Latif Arusoglu; Meike Freitag; Ramona Cebulla; Kornelia Jaquet; Reiner Körfer; Dirk V Lewinski; Astrid Kassner; Otto-Erich Brodde; Harald Kögler; Aly El-Banayosy; Burkert Pieske
Selective upregulation of beta1-adrenergic receptors and dephosphorylation of troponin I in end-stage heart failure patients supported by ventricular assist devices.
Journal of molecular and cellular cardiology 2006;41(3):441-50.
2006: Hendrik Milting; Nina Lukas; Bärbel Klauke; Reiner Körfer; Andreas Perrot; Karl Josef Osterziel; Jürgen Vogt; Stefan Peters; Rolf Thieleczek; Magdolna Varsányi
Composite polymorphisms in the ryanodine receptor 2 gene associated with arrhythmogenic right ventricular cardiomyopathy.
Cardiovascular research 2006;71(3):496-505.
2006: Peter F.M. van der Ven; Elisabeth Ehler; Padmanabhan Vakeel; Stefan Eulitz; Jörg A Schenk; Hendrik Milting; Burkhard Micheel; Dieter O Fürst
Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.
Experimental cell research 2006;312(11):2154-67.
2006: Harald Kögler; Peter Schott; Karl Toischer; Hendrik Milting; Phuc Nguyen Van; Michael Kohlhaas; Cornelia Grebe; Astrid Kassner; Erik Domeier; Nils Teucher; Tim Seidler; Ralph Knöll; Lars S Maier; Aly El-Banayosy; Reiner Körfer; Gerd Hasenfuss
Relevance of brain natriuretic peptide in preload-dependent regulation of cardiac sarcoplasmic reticulum Ca2+ ATPase expression.
Circulation 2006;113(23):2724-32.
2006: Hendrik Milting; Astrid Kassner; Latif Arusoglu; Helmut E Meyer; Michiel Morshuis; Ramona Brendel; Bärbel Klauke; Aly El-Banayosy; Reiner Körfer
Influence of ACE-inhibition and mechanical unloading on the regulation of extracellular matrix proteins in the myocardium of heart transplantation candidates bridged by ventricular assist devices.
European journal of heart failure 2006;8(3):278-83.
2005: Stephane Heymans; Blanche Schroen; Pieter Vermeersch; Hendrik Milting; Fangye Gao; Astrid Kassner; Hilde Gillijns; Paul Herijgers; Willem Flameng; Peter Carmeliet; Frans Van de Werf; Yigal M Pinto; Stefan Janssens
Increased cardiac expression of tissue inhibitor of metalloproteinase-1 and tissue inhibitor of metalloproteinase-2 is related to cardiac fibrosis and dysfunction in the chronic pressure-overloaded human heart.
Circulation 2005;112(8):1136-44.
2005: Aly El-Banayosy; Latif Arusoglu; Michiel Morshuis; Lukasz Kizner; Gero Tenderich; Peter Sarnowski; Hendrik Milting; Reiner Koerfer
CardioWest total artificial heart: Bad Oeynhausen experience.
The Annals of thoracic surgery 2005;80(2):548-52.
2005: Aly El-Banayosy; Dagmar Cobaugh; Armin Zittermann; Lukasz Kitzner; Latif Arusoglu; Michiel Morshuis; Hendrik Milting; Gero Tenderich; Reiner Koerfer
A multidisciplinary network to save the lives of severe, persistent cardiogenic shock patients.
The Annals of thoracic surgery 2005;80(2):543-7.
2004: Hendrik Milting; Monika Jacob; Astrid Kassner; Peter Heimann; Hans Georg Mannherz; Gabriele Becker; Helmut E Meyer; Dietmar Böthig; Latif Arusoglu; Michiel Morshuis; Reiner Körfer; Aly El-Banayosy
The structural examination of myocardial samples from patients with end-stage heart failure supported by ventricular assist devices using electron microscopy and amino acid analysis reveals low degree of reverse remodeling.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2004;23(4):396-404.
2003: Hendrik Milting; Astrid Kassner; Dietmar Böthig; Rolf Thieleczek; Harald Kögler; Nils Teucher; Helmut E Meyer; Latif Arusoglu; Kazutomo Minami; Reiner Körfer; Aly El-Banayosy
Differential regulation of Ca2+-dependent ATPase-activity in left ventricular myocardium during mechanical circulatory support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2003;22(11):1209-16.
2001: Hendrik Milting; Paul Janssen; Thekla Wangemann; Harald Kögler; E Domeier; Tim Seidler; Kavous Hakim; M Grapow; Oliver Zeitz; Jürgen Prestle; Hans Zerkowski
FK506 does not affect cardiac contractility and adrenergic response in vitro.
European journal of pharmacology 2001;430(2-3):299-304.
2001: Hendrik Milting; Aly El-Banayosy; Astrid Kassner; O Fey; Peter Sarnowski; Latif Arusoglu; Rolf Thieleczek; Thomas BRINKMANN; Knut Kleesiek; Reiner Körfer
The time course of natriuretic hormones as plasma markers of myocardial recovery in heart transplant candidates during ventricular assist device support reveals differences among device types.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001;20(9):949-55.
2001: Aly El-Banayosy; Reiner Körfer; Latif Arusoglu; Lukasz Kizner; Michiel Morshuis; Hendrik Milting; Gero Tenderich; O Fey; Kenichirou Minami
Device and patient management in a bridge-to-transplant setting.
The Annals of thoracic surgery 2001;71(3 Suppl):S98-102; discussion S114-5.
2001: Aly El-Banayosy; O Fey; Peter Sarnowski; Latif Arusoglu; Dietmar Boethig; Hendrik Milting; Michiel Morshuis; Reiner Körfer
Midterm follow-up of patients discharged from hospital under left ventricular assistance.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001;20(1):53-8.
1999: Babett Bartling; Hendrik Milting; H Schumann; Dorothea Darmer; Latif Arusoglu; Michael Koerner; Aly El-Banayosy; Reiner Koerfer; Juergen Holtz; Hans Zerkowski
Myocardial gene expression of regulators of myocyte apoptosis and myocyte calcium homeostasis during hemodynamic unloading by ventricular assist devices in patients with end-stage heart failure.
Circulation 1999;100(19 Suppl):II216-23.
1999: Hendrik Milting; Babett Bartling; H Schumann; Aly El-Banayosy; Stefan Wlost; F Rüter; Dorothea Darmer; Juergen Holtz; Reiner Körfer; Hans Zerkowski
Altered levels of mRNA of apoptosis-mediating genes after mid-term mechanical ventricular support in dilative cardiomyopathy--first results of the Halle Assist Induced Recovery Study (HAIR).
The Thoracic and cardiovascular surgeon 1999;47(1):48-50.
1993: Hendrik Milting; Wolf-Rüdiger Thies; Thomas Breymann; J Léger; Jean J Léger; H Meyer; R Körfer; Harald Jockusch
Coexpression of alpha and beta myosin heavy-chain isoforms in atria of neonates and infants with congenital heart disease.
Basic research in cardiology 1993;88(4):371-7.
1991: T Brand; Hendrik Milting; M Zippel; Harald Jockusch
Differential synthesis by cultured atrial and ventricular rat cardiac myocytes of myosin light chain isoforms.
FEBS letters 1991;283(2):289-90.