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John Minna
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149
Gazdar, Adi
37
Virmani, Arvind
37
Wistuba, Ignacio
25
Sekido, Yoshitaka
24
Toyooka, Shinichi
23
Fong, Kwun
19
Girard, Luc
18
Roth, Jack
18
Lerman, Michael
18
Milchgrub, Sara
17
Latif, Farida
17
Shay, Jerry
16
Johnson, Bruce
16
Zöchbauer-Müller, Sabine
15
Ji, Lin
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All Publications
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2009: Du Liqin; Schageman Jeoffrey J; Subauste Maria C; Saber Barbara; Hammond Scott M; Prudkin Ludmila; Wistuba Ignacio I; Ji Lin; Roth Jack A; Minna John D; Pertsemlidis Alexander
miR-93, miR-98, and miR-197 regulate expression of tumor suppressor gene FUS1.
Molecular cancer research : MCR 2009;7(8):1234-43.
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2009: Blanco Raquel; Iwakawa Reika; Tang Moying; Kohno Takashi; Angulo Barbara; Pio Ruben; Montuenga Luis M; Minna John D; Yokota Jun; Sanchez-Cespedes Montse
A gene-alteration profile of human lung cancer cell lines.
Human mutation 2009;30(8):1199-206.
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2009: Ivanova Margarita M; Mazhawidza Williard; Dougherty Susan M; Minna John D; Klinge Carolyn M
Activity and intracellular location of estrogen receptors alpha and beta in human bronchial epithelial cells.
Molecular and cellular endocrinology 2009;305(1-2):12-21.
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2009: Choi Kuicheon; Ahn Young-Ho; Gibbons Don L; Tran Hai T; Creighton Chad J; Girard Luc; Minna John D; Qin F Xiao-Feng; Kurie Jonathan M
Distinct biological roles for the notch ligands Jagged-1 and Jagged-2.
The Journal of biological chemistry 2009;284(26):17766-74.
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2009: Gazdar Adi F; Minna John D
Multifocal lung cancers--clonality vs field cancerization and does it matter?
Journal of the National Cancer Institute 2009;101(8):541-3.
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2009: Sos Martin L; Koker Mirjam; Weir Barbara A; Heynck Stefanie; Rabinovsky Rosalia; Zander Thomas; Seeger Jens M; Weiss Jonathan; Fischer Florian; Frommolt Peter; Michel Kathrin; Peifer Martin; Mermel Craig; Girard Luc; Peyton Michael; Gazdar Adi F; Minna John D; Garraway Levi A; Kashkar Hamid; Pao William; Meyerson Matthew; Thomas Roman K
PTEN loss contributes to erlotinib resistance in EGFR-mutant lung cancer by activation of Akt and EGFR.
Cancer research 2009;69(8):3256-61.
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2009: McMahon Kerrie-Ann; Zajicek Hubert; Li Wei-Ping; Peyton Michael J; Minna John D; Hernandez V James; Luby-Phelps Katherine; Anderson Richard G W
SRBC/cavin-3 is a caveolin adapter protein that regulates caveolae function.
The EMBO journal 2009;28(8):1001-15.
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2009: Kubo Takafumi; Yamamoto Hiromasa; Lockwood William W; Valencia Ilse; Soh Junichi; Peyton Michael; Jida Masaru; Otani Hiroki; Fujii Tetsuya; Ouchida Mamoru; Takigawa Nagio; Kiura Katsuyuki; Shimizu Kenji; Date Hiroshi; Minna John D; Varella-Garcia Marileila; Lam Wan L; Gazdar Adi F; Toyooka Shinichi
MET gene amplification or EGFR mutation activate MET in lung cancers untreated with EGFR tyrosine kinase inhibitors.
International journal of cancer. Journal international du cancer 2009;124(8):1778-84.
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2009: Zhang Wei; Peyton Michael; Xie Yang; Soh Junichi; Minna John D; Gazdar Adi F; Frenkel Eugene P
Histone deacetylase inhibitor romidepsin enhances anti-tumor effect of erlotinib in non-small cell lung cancer (NSCLC) cell lines.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2009;4(2):161-6.
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2009: Soh Junichi; Okumura Naoki; Lockwood William W; Yamamoto Hiromasa; Shigematsu Hisayuki; Zhang Wei; Chari Raj; Shames David S; Tang Ximing; MacAulay Calum; Varella-Garcia Marileila; Vooder Tõnu; Wistuba Ignacio I; Lam Stephen; Brekken Rolf; Toyooka Shinichi; Minna John D; Lam Wan L; Gazdar Adi F
Oncogene mutations, copy number gains and mutant allele specific imbalance (MASI) frequently occur together in tumor cells.
PloS one 2009;4(10):e7464.
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2009: Kao Jessica; Salari Keyan; Bocanegra Melanie; Choi Yoon-La; Girard Luc; Gandhi Jeet; Kwei Kevin A; Hernandez-Boussard Tina; Wang Pei; Gazdar Adi F; Minna John D; Pollack Jonathan R
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery.
PloS one 2009;4(7):e6146.
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2009: Gandhi Jeet; Zhang Jianling; Xie Yang; Soh Junichi; Shigematsu Hisayuki; Zhang Wei; Yamamoto Hiromasa; Peyton Michael; Girard Luc; Lockwood William W; Lam Wan L; Varella-Garcia Marileila; Minna John D; Gazdar Adi F
Alterations in genes of the EGFR signaling pathway and their relationship to EGFR tyrosine kinase inhibitor sensitivity in lung cancer cell lines.
PloS one 2009;4(2):e4576.
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2008: Dowell Jonathan; Minna John D
Small-cell lung cancer: translational research enroute to therapeutic advances.
Oncology (Williston Park, N.Y.) 2008;22(13):1493, 1495.
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2008: Castro-Rivera Emely; Ran Sophia; Brekken Rolf A; Minna John D
Semaphorin 3B inhibits the phosphatidylinositol 3-kinase/Akt pathway through neuropilin-1 in lung and breast cancer cells.
Cancer research 2008;68(20):8295-303.
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2008: Shivapurkar Narayan; Stastny Victor; Okumura Naoki; Girard Luc; Xie Yang; Prinsen Clemens; Thunnissen Frederik B; Wistuba Ignacio I; Czerniak Bogdan; Frenkel Eugene; Roth Jack A; Liloglou Triantafillos; Xinarianos George; Field John K; Minna John D; Gazdar Adi F
Cytoglobin, the newest member of the globin family, functions as a tumor suppressor gene.
Cancer research 2008;68(18):7448-56.
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2008: Guha Udayan; Chaerkady Raghothama; Marimuthu Arivusudar; Patterson A Scott; Kashyap Manoj K; Harsha H C; Sato Mitsuo; Bader Joel S; Lash Alex E; Minna John D; Pandey Akhilesh; Varmus Harold E
Comparisons of tyrosine phosphorylated proteins in cells expressing lung cancer-specific alleles of EGFR and KRAS.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(37):14112-7.
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2008: Yamamoto Hiromasa; Shigematsu Hisayuki; Nomura Masaharu; Lockwood William W; Sato Mitsuo; Okumura Naoki; Soh Junichi; Suzuki Makoto; Wistuba Ignacio I; Fong Kwun M; Lee Huei; Toyooka Shinichi; Date Hiroshi; Lam Wan L; Minna John D; Gazdar Adi F
PIK3CA mutations and copy number gains in human lung cancers.
Cancer research 2008;68(17):6913-21.
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2008: Gazdar Adi F; Minna John D
Deregulated EGFR signaling during lung cancer progression: mutations, amplicons, and autocrine loops.
Cancer prevention research (Philadelphia, Pa.) 2008;1(3):156-60.
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2008: Xie Yang; Minna John D
Predicting the future for people with lung cancer.
Nature medicine 2008;14(8):812-3.
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2008: Einhorn Lawrence H; Bonomi Philip; Bunn Paul A; Camidge D Ross; Carbone David Paul; Choy Hak; Dubinett Steven M; Gandara David R; Gaspar Laurie E; Govindan Ramaswamy; Johnson David H; Minna John D; Scagliotti Giorgio; West Howard J; Herbst Roy S
Summary report 7th Annual Targeted Therapies of the Treatment of Lung Cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2008;3(5):545-55.
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2008: Whitehurst Angelique W; Ram Rosalyn; Shivakumar Latha; Gao Boning; Minna John D; White Michael A
The RASSF1A tumor suppressor restrains anaphase-promoting complex/cyclosome activity during the G1/S phase transition to promote cell cycle progression in human epithelial cells.
Molecular and cellular biology 2008;28(10):3190-7.
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2008: Shivapurkar Narayan; Stastny Victor; Xie Yang; Prinsen Clemens; Frenkel Eugene; Czerniak Bogdan; Thunnissen Frederik B; Minna John D; Gazdar Adi F
Differential methylation of a short CpG-rich sequence within exon 1 of TCF21 gene: a promising cancer biomarker assay.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(4):995-1000.
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2008: Iwanaga Kentaro; Yang Yanan; Raso Maria Gabriela; Ma Lijiang; Hanna Amy E; Thilaganathan Nishan; Moghaddam Seyed; Evans Christopher M; Li Huaiguang; Cai Wei-Wen; Sato Mitsuo; Minna John D; Wu Hong; Creighton Chad J; Demayo Francesco J; Wistuba Ignacio I; Kurie Jonathan M
Pten inactivation accelerates oncogenic K-ras-initiated tumorigenesis in a mouse model of lung cancer.
Cancer research 2008;68(4):1119-27.
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2008: Shames David S; Minna John D
IP6K2 is a client for HSP90 and a target for cancer therapeutics development.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(5):1389-90.
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2008: Gao Boning; Xie Xian-Jin; Huang Chunxian; Shames David S; Chen Tina T-L; Lewis Cheryl M; Bian Aihua; Zhang Bifeng; Olopade Olufunmilayo I; Garber Judy E; Euhus David M; Tomlinson Gail E; Minna John D
RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers.
Cancer research 2008;68(1):22-5.
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2008: Prudkin Ludmila; Behrens Carmen; Liu Diane D; Zhou Xian; Ozburn Natalie C; Bekele B Nebiyou; Minna John D; Moran Cesar; Roth Jack A; Ji Lin; Wistuba Ignacio I
Loss and reduction of FUS1 protein expression is a frequent phenomenon in the pathogenesis of lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):41-7.
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2008: Eckstein Niels; Servan Kati; Girard Luc; Cai Di; von Jonquieres Georg; Jaehde Ulrich; Kassack Matthias U; Gazdar Adi F; Minna John D; Royer Hans-Dieter
Epidermal growth factor receptor pathway analysis identifies amphiregulin as a key factor for cisplatin resistance of human breast cancer cells.
The Journal of biological chemistry 2008;283(2):739-50.
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2008: Deus Helena F; Stanislaus Romesh; Behrens Carmen; Wistuba Ignacio I; Minna John D; Garner Harold R; Swisher Stephen G; Roth Jack A; Correa Arlene M; Broom Bradley; Coombes Kevin; Almeida Jonas S
Data driven semantic integration of translational lung cancer research at MDAnderson Cancer Center.
AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium 2008;():927.
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2008: Deus Helena F; Stanislaus Romesh; Veiga Diogo F; Behrens Carmen; Wistuba Ignacio I; Minna John D; Garner Harold R; Swisher Stephen G; Roth Jack A; Correa Arlene M; Broom Bradley; Coombes Kevin; Chang Allen; Vogel Lynn H; Almeida Jonas S
A Semantic Web management model for integrative biomedical informatics.
PloS one 2008;3(8):e2946.
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2007: Petersen Sean L; Wang Lai; Yalcin-Chin Asligul; Li Lin; Peyton Michael; Minna John; Harran Patrick; Wang Xiaodong
Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis.
Cancer cell 2007;12(5):445-56.
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2007: Jayachandran Gitanjali; Sazaki Ji-ichiro; Nishizaki Masahito; Xu Kai; Girard Luc; Minna John D; Roth Jack A; Ji Lin
Fragile histidine triad-mediated tumor suppression of lung cancer by targeting multiple components of the Ras/Rho GTPase molecular switch.
Cancer research 2007;67(21):10379-88.
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2007: Hittelman Walter N; Liu Diane D; Kurie Jonathan M; Lotan Reuben; Lee Jin Soo; Khuri Fadlo; Ibarguen Heladio; Morice Rodolfo C; Walsh Garrett; Roth Jack A; Minna John; Ro Jae Y; Broxson Anita; Hong Waun Ki; Lee J Jack
Proliferative changes in the bronchial epithelium of former smokers treated with retinoids.
Journal of the National Cancer Institute 2007;99(21):1603-12.
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2007: Nagayama Kazuhiro; Kohno Takashi; Sato Masanori; Arai Yasuhito; Minna John D; Yokota Jun
Homozygous deletion scanning of the lung cancer genome at a 100-kb resolution.
Genes, chromosomes & cancer 2007;46(11):1000-10.
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2007: Liu Ming; Yang Seok-Chul; Sharma Sherven; Luo Jie; Cui Xiaoyan; Peebles Katherine A; Huang Min; Sato Mitsuo; Ramirez Ruben D; Shay Jerry W; Minna John D; Dubinett Steven M
EGFR signaling is required for TGF-beta 1 mediated COX-2 induction in human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2007;37(5):578-88.
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2007: Sun Sophie; Schiller Joan H; Spinola Monica; Minna John D
New molecularly targeted therapies for lung cancer.
The Journal of clinical investigation 2007;117(10):2740-50.
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2007: Minna John D; Girard Luc; Xie Yang
Tumor mRNA expression profiles predict responses to chemotherapy.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(28):4329-36.
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2007: Lin J; Sun T; Ji L; Deng W; Roth J; Minna J; Arlinghaus R
Oncogenic activation of c-Abl in non-small cell lung cancer cells lacking FUS1 expression: inhibition of c-Abl by the tumor suppressor gene product Fus1.
Oncogene 2007;26(49):6989-96.
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2007: Gorlov Ivan P; Meyer Peter; Liloglou Triantafillos; Myles Jonathan; Boettger Melanie Barbara; Cassidy Adrian; Girard Luc; Minna John D; Fischer Reiner; Duffy Stephen; Spitz Margaret R; Haeussinger Karl; Kammerer Stefan; Cantor Charles; Dierkesmann Rainer; Field John K; Amos Christopher I
Seizure 6-like (SEZ6L) gene and risk for lung cancer.
Cancer research 2007;67(17):8406-11.
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2007: Padrón David; Sato Mitsuo; Shay Jerry W; Gazdar Adi F; Minna John D; Roth Michael G
Epidermal growth factor receptors with tyrosine kinase domain mutations exhibit reduced Cbl association, poor ubiquitylation, and down-regulation but are efficiently internalized.
Cancer research 2007;67(16):7695-702.
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2007: Matsumoto S; Iwakawa R; Takahashi K; Kohno T; Nakanishi Y; Matsuno Y; Suzuki K; Nakamoto M; Shimizu E; Minna J D; Yokota J
Prevalence and specificity of LKB1 genetic alterations in lung cancers.
Oncogene 2007;26(40):5911-8.
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2007: Robinson J D; Lam C Y; Minnix J A; Wetter D W; Tomlinson G E; Minna J D; Chen T T-L; Cinciripini P M
The DRD2 TaqI-B polymorphism and its relationship to smoking abstinence and withdrawal symptoms.
The pharmacogenomics journal 2007;7(4):266-74.
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2007: Ohtani Shoichiro; Iwamaru Arifumi; Deng Wuguo; Ueda Kentaro; Wu Guanglin; Jayachandran Gitanjali; Kondo Seiji; Atkinson Edward N; Minna John D; Roth Jack A; Ji Lin
Tumor suppressor 101F6 and ascorbate synergistically and selectively inhibit non-small cell lung cancer growth by caspase-independent apoptosis and autophagy.
Cancer research 2007;67(13):6293-303.
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2007: Bey Erik A; Bentle Melissa S; Reinicke Kathryn E; Dong Ying; Yang Chin-Rang; Girard Luc; Minna John D; Bornmann William G; Gao Jinming; Boothman David A
An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(28):11832-7.
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2007: Das Amit K; Chen Benjamin P; Story Michael D; Sato Mitsuo; Minna John D; Chen David J; Nirodi Chaitanya S
Somatic mutations in the tyrosine kinase domain of epidermal growth factor receptor (EGFR) abrogate EGFR-mediated radioprotection in non-small cell lung carcinoma.
Cancer research 2007;67(11):5267-74.
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2007: Shames David S; Minna John D; Gazdar Adi F
Methods for detecting DNA methylation in tumors: from bench to bedside.
Cancer letters 2007;251(2):187-98.
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2007: Sekine Ikuo; Minna John D; Nishio Kazuto; Saijo Nagahiro; Tamura Tomohide
Genes regulating the sensitivity of solid tumor cell lines to cytotoxic agents: a literature review.
Japanese journal of clinical oncology 2007;37(5):329-36.
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2007: Vikis Haris; Sato Mitsuo; James Michael; Wang Daolong; Wang Yian; Wang Min; Jia Dongmei; Liu Yan; Bailey-Wilson Joan E; Amos Christopher I; Pinney Susan M; Petersen Gloria M; de Andrade Mariza; Yang Ping; Wiest Jonathan S; Fain Pamela R; Schwartz Ann G; Gazdar Adi; Gaba Colette; Rothschild Henry; Mandal Diptasri; Kupert Elena; Seminara Daniela; Viswanathan Avinash; Govindan Ramaswamy; Minna John; Anderson Marshall W; You Ming
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.
Cancer research 2007;67(10):4665-70.
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2007: Lam David Chi-Leung; Girard Luc; Ramirez Ruben; Chau Wing-Shun; Suen Wai-sing; Sheridan Shelley; Tin Vicky P C; Chung Lap-ping; Wong Maria P; Shay Jerry W; Gazdar Adi F; Lam Wah-kit; Minna John D
Expression of nicotinic acetylcholine receptor subunit genes in non-small-cell lung cancer reveals differences between smokers and nonsmokers.
Cancer research 2007;67(10):4638-47.
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2007: Nomura Masaharu; Shigematsu Hisayuki; Li Lin; Suzuki Makoto; Takahashi Takao; Estess Pila; Siegelman Mark; Feng Ziding; Kato Harubumi; Marchetti Antonio; Shay Jerry W; Spitz Margaret R; Wistuba Ignacio I; Minna John D; Gazdar Adi F
Polymorphisms, mutations, and amplification of the EGFR gene in non-small cell lung cancers.
PLoS medicine 2007;4(4):e125.
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2007: Whitehurst Angelique W; Bodemann Brian O; Cardenas Jessica; Ferguson Deborah; Girard Luc; Peyton Michael; Minna John D; Michnoff Carolyn; Hao Weihua; Roth Michael G; Xie Xian-Jin; White Michael A
Synthetic lethal screen identification of chemosensitizer loci in cancer cells.
Nature 2007;446(7137):815-9.
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2007: Sato Mitsuo; Shames David S; Gazdar Adi F; Minna John D
A translational view of the molecular pathogenesis of lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2007;2(4):327-43.
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2007: Suzuki Makoto; Shigematsu Hisayuki; Shames David S; Sunaga Noriaki; Takahashi Takao; Shivapurkar Narayan; Iizasa Toshihiko; Minna John D; Fujisawa Takehiko; Gazdar Adi F
Methylation and gene silencing of the Ras-related GTPase gene in lung and breast cancers.
Annals of surgical oncology 2007;14(4):1397-404.
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2007: Khatlani T S; Wislez M; Sun M; Srinivas H; Iwanaga K; Ma L; Hanna A E; Liu D; Girard L; Kim Y H; Pollack J R; Minna J D; Wistuba I I; Kurie J M
c-Jun N-terminal kinase is activated in non-small-cell lung cancer and promotes neoplastic transformation in human bronchial epithelial cells.
Oncogene 2007;26(18):2658-66.
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2007: Shames David S; Minna John D; Gazdar Adi F
DNA methylation in health, disease, and cancer.
Current molecular medicine 2007;7(1):85-102.
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2007: Sato Naohito; Fukui Takayuki; Taniguchi Tetsuo; Yokoyama Toshihiko; Kondo Masashi; Nagasaka Tetsuro; Goto Yasuhiro; Gao Wentao; Ueda Yuichi; Yokoi Kohei; Minna John D; Osada Hirotaka; Kondo Yutaka; Sekido Yoshitaka
RhoB is frequently downregulated in non-small-cell lung cancer and resides in the 2p24 homozygous deletion region of a lung cancer cell line.
International journal of cancer. Journal international du cancer 2007;120(3):543-51.
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2007: Lea Jayanthi S; Sunaga Noriaki; Sato Mitsuo; Kalahasti Geetha; Miller David S; Minna John D; Muller Carolyn Y
Silencing of HPV 18 oncoproteins With RNA interference causes growth inhibition of cervical cancer cells.
Reproductive sciences (Thousand Oaks, Calif.) 2007;14(1):20-8.
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2007: Deng Wu-Guo; Kawashima Hiroyaki; Wu Guanglin; Jayachandran Gitanjali; Xu Kai; Minna John D; Roth Jack A; Ji Lin
Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells.
Cancer research 2007;67(2):709-17.
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2007: Wang Min; Vikis Haris G; Wang Yian; Jia Dongmei; Wang Daolong; Bierut Laura J; Bailey-Wilson Joan E; Amos Christopher I; Pinney Susan M; Petersen Gloria M; de Andrade Mariza; Yang Ping; Wiest Jonathan S; Fain Pamela R; Schwartz Ann G; Gazdar Adi; Minna John; Gaba Colette; Rothschild Henry; Mandal Diptasri; Kupert Elena; Seminara Daniela; Liu Yan; Viswanathan Avinash; Govindan Ramaswamy; Anderson Marshall W; You Ming
Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.
Cancer research 2007;67(1):93-9.
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2007: Sathyanarayana Ubaradka G; Moore Angela Yen; Li Lin; Padar Asha; Majmudar Kuntal; Stastny Victor; Makarla Prakash; Suzuki Makoto; Minna John D; Feng Ziding; Gazdar Adi F
Sun exposure related methylation in malignant and non-malignant skin lesions.
Cancer letters 2007;245(1-2):112-20.
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2007: Shah Jyoti K; Garner Harold R; White Michael A; Shames David S; Minna John D
sIR: siRNA Information Resource, a web-based tool for siRNA sequence design and analysis and an open access siRNA database.
BMC bioinformatics 2007;8():178.
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2006: Shames David S; Girard Luc; Gao Boning; Sato Mitsuo; Lewis Cheryl M; Shivapurkar Narayan; Jiang Aixiang; Perou Charles M; Kim Young H; Pollack Jonathan R; Fong Kwun M; Lam Chi-Leung; Wong Maria; Shyr Yu; Nanda Rita; Olopade Olufunmilayo I; Gerald William; Euhus David M; Shay Jerry W; Gazdar Adi F; Minna John D
A genome-wide screen for promoter methylation in lung cancer identifies novel methylation markers for multiple malignancies.
PLoS medicine 2006;3(12):e486.
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2006: Helfrich Barbara A; Raben David; Varella-Garcia Marileila; Gustafson Dan; Chan Daniel C; Bemis Lynne; Coldren Chris; Barón Anna; Zeng Chan; Franklin Wilbur A; Hirsch Fred R; Gazdar Adi; Minna John; Bunn Paul A
Antitumor activity of the epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor gefitinib (ZD1839, Iressa) in non-small cell lung cancer cell lines correlates with gene copy number and EGFR mutations but not EGFR protein levels.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(23):7117-25.
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2006: Lam David C L; Girard Luc; Suen Wai-Sing; Chung Lap-ping; Tin Vicky P C; Lam Wah-kit; Minna John D; Wong Maria P
Establishment and expression profiling of new lung cancer cell lines from Chinese smokers and lifetime never-smokers.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(9):932-42.
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2006: Ueda Kentaro; Kawashima Hiroyuki; Ohtani Shoichiro; Deng Wu-Guo; Ravoori Murali; Bankson Jim; Gao Boning; Girard Luc; Minna John D; Roth Jack A; Kundra Vikas; Ji Lin
The 3p21.3 tumor suppressor NPRL2 plays an important role in cisplatin-induced resistance in human non-small-cell lung cancer cells.
Cancer research 2006;66(19):9682-90.
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2006: Das Amit K; Sato Mitsuo; Story Michael D; Peyton Michael; Graves Robert; Redpath Stella; Girard Luc; Gazdar Adi F; Shay Jerry W; Minna John D; Nirodi Chaitanya S
Non-small-cell lung cancers with kinase domain mutations in the epidermal growth factor receptor are sensitive to ionizing radiation.
Cancer research 2006;66(19):9601-8.
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2006: Coyle Yvonne M; Minahjuddin Abu T; Hynan Linda S; Minna John D
An ecological study of the association of metal air pollutants with lung cancer incidence in Texas.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):654-61.
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2006: Janowski Bethany A; Huffman Kenneth E; Schwartz Jacob C; Ram Rosalyn; Nordsell Robert; Shames David S; Minna John D; Corey David R
Involvement of AGO1 and AGO2 in mammalian transcriptional silencing.
Nature structural & molecular biology 2006;13(9):787-92.
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2006: Zhou Bin-Bing S; Peyton Michael; He Biao; Liu Changnian; Girard Luc; Caudler Eian; Lo Yvonne; Baribaud Frederic; Mikami Iwao; Reguart Noemi; Yang Gengjie; Li Yanlong; Yao Wenqing; Vaddi Kris; Gazdar Adi F; Friedman Steven M; Jablons David M; Newton Robert C; Fridman Jordan S; Minna John D; Scherle Peggy A
Targeting ADAM-mediated ligand cleavage to inhibit HER3 and EGFR pathways in non-small cell lung cancer.
Cancer cell 2006;10(1):39-50.
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2006: Coe B P; Lockwood W W; Girard L; Chari R; Macaulay C; Lam S; Gazdar A F; Minna J D; Lam W L
Differential disruption of cell cycle pathways in small cell and non-small cell lung cancer.
British journal of cancer 2006;94(12):1927-35.
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2006: Suzuki Makoto; Shigematsu Hisayuki; Iizasa Toshihiko; Hiroshima Kenzo; Nakatani Yukio; Minna John D; Gazdar Adi F; Fujisawa Takehiko
Exclusive mutation in epidermal growth factor receptor gene, HER-2, and KRAS, and synchronous methylation of nonsmall cell lung cancer.
Cancer 2006;106(10):2200-7.
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2006: Vaughan Melville B; Ramirez Ruben D; Wright Woodring E; Minna John D; Shay Jerry W
A three-dimensional model of differentiation of immortalized human bronchial epithelial cells.
Differentiation; research in biological diversity 2006;74(4):141-8.
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2006: Wislez Marie; Fujimoto Nobukazu; Izzo Julie G; Hanna Amy E; Cody Dianna D; Langley Robert R; Tang Hongli; Burdick Marie D; Sato Mitsuo; Minna John D; Mao Li; Wistuba Ignacio; Strieter Robert M; Kurie Jonathan M
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Cancer research 2006;66(8):4198-207.
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2006: Dowell Jonathan E; Minna John D
EGFR mutations and molecularly targeted therapy: a new era in the treatment of lung cancer.
Nature clinical practice. Oncology 2006;3(4):170-1.
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2006: Agirre Xabier; Román-Gómez José; Vázquez Iria; Jiménez-Velasco Antonio; Garate Leire; Montiel-Duarte Cristina; Artieda Paula; Cordeu Lucia; Lahortiga Idoya; Calasanz María José; Heiniger Anabel; Torres Antonio; Minna John D; Prósper Felipe
Abnormal methylation of the common PARK2 and PACRG promoter is associated with downregulation of gene expression in acute lymphoblastic leukemia and chronic myeloid leukemia.
International journal of cancer. Journal international du cancer 2006;118(8):1945-53.
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2006: Tam Issan Yee San; Chung Lap Ping; Suen Wai Sing; Wang Elaine; Wong May C M; Ho Kok Keung; Lam Wah Kit; Chiu Shui Wah; Girard Luc; Minna John D; Gazdar Adi F; Wong Maria P
Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1647-53.
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2006: Moshnikova Anna; Frye Judson; Shay Jerry W; Minna John D; Khokhlatchev Andrei V
The growth and tumor suppressor NORE1A is a cytoskeletal protein that suppresses growth by inhibition of the ERK pathway.
The Journal of biological chemistry 2006;281(12):8143-52.
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2006: Agirre X; Román-Gómez J; Jiménez-Velasco A; Garate L; Montiel-Duarte C; Navarro G; Vázquez I; Zalacain M; Calasanz M J; Heiniger A; Torres A; Minna J D; Prósper F
ASPP1, a common activator of TP53, is inactivated by aberrant methylation of its promoter in acute lymphoblastic leukemia.
Oncogene 2006;25(13):1862-70.
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2006: Garnis Cathie; Lockwood William W; Vucic Emily; Ge Yong; Girard Luc; Minna John D; Gazdar Adi F; Lam Stephen; MacAulay Calum; Lam Wan L
High resolution analysis of non-small cell lung cancer cell lines by whole genome tiling path array CGH.
International journal of cancer. Journal international du cancer 2006;118(6):1556-64.
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2006: Sato Mitsuo; Vaughan Melville B; Girard Luc; Peyton Michael; Lee Woochang; Shames David S; Ramirez Ruben D; Sunaga Noriaki; Gazdar Adi F; Shay Jerry W; Minna John D
Multiple oncogenic changes (K-RAS(V12), p53 knockdown, mutant EGFRs, p16 bypass, telomerase) are not sufficient to confer a full malignant phenotype on human bronchial epithelial cells.
Cancer research 2006;66(4):2116-28.
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2006: Takahashi Kenji; Kohno Takashi; Ajima Rieko; Sasaki Hiroki; Minna John D; Fujiwara Toshiyoshi; Tanaka Noriaki; Yokota Jun
Homozygous deletion and reduced expression of the DOCK8 gene in human lung cancer.
International journal of oncology 2006;28(2):321-8.
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2006: Heller Gerwin; Fong Kwun M; Girard Luc; Seidl Sonja; End-Pfützenreuter Adelheid; Lang György; Gazdar Adi F; Minna John D; Zielinski Christoph C; Zöchbauer-Müller Sabine
Expression and methylation pattern of TSLC1 cascade genes in lung carcinomas.
Oncogene 2006;25(6):959-68.
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2006: Iijima Hironobu; Tomizawa Yoshio; Iwasaki Yasuki; Sato Koji; Sunaga Noriaki; Dobashi Kunio; Saito Ryusei; Nakajima Takashi; Minna John D; Mori Masatomo
Genetic and epigenetic inactivation of LTF gene at 3p21.3 in lung cancers.
International journal of cancer. Journal international du cancer 2006;118(4):797-801.
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2006: Sekine Ikuo; Minna John D; Nishio Kazuto; Tamura Tomohide; Saijo Nagahiro
A literature review of molecular markers predictive of clinical response to cytotoxic chemotherapy in patients with lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(1):31-7.
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2006: Witta Samir E; Gemmill Robert M; Hirsch Fred R; Coldren Christopher D; Hedman Karla; Ravdel Larisa; Helfrich Barbara; Dziadziuszko Rafal; Chan Daniel C; Sugita Michio; Chan Zeng; Baron Anna; Franklin Wilbur; Drabkin Harry A; Girard Luc; Gazdar Adi F; Minna John D; Bunn Paul A
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.
Cancer research 2006;66(2):944-50.
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2006: Coe Bradley P; Lee Eric H L; Chi Bryan; Girard Luc; Minna John D; Gazdar Adi F; Lam Stephen; MacAulay Calum; Lam Wan L
Gain of a region on 7p22.3, containing MAD1L1, is the most frequent event in small-cell lung cancer cell lines.
Genes, chromosomes & cancer 2006;45(1):11-9.
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2005: Fujimoto Nobukazu; Wislez Marie; Zhang Jie; Iwanaga Kentaro; Dackor Jennifer; Hanna Amy E; Kalyankrishna Shailaja; Cody Dianna D; Price Roger E; Sato Mitsuo; Shay Jerry W; Minna John D; Peyton Michael; Tang Ximing; Massarelli Erminia; Herbst Roy; Threadgill David W; Wistuba Ignacio I; Kurie Jonathan M
High expression of ErbB family members and their ligands in lung adenocarcinomas that are sensitive to inhibition of epidermal growth factor receptor.
Cancer research 2005;65(24):11478-85.
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2005: Sato Masamitsu; Takahashi Kenji; Nagayama Kazuhiro; Arai Yasuhito; Ito Nobue; Okada Mitsumasa; Minna John D; Yokota Jun; Kohno Takashi
Identification of chromosome arm 9p as the most frequent target of homozygous deletions in lung cancer.
Genes, chromosomes & cancer 2005;44(4):405-14.
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2005: Cinciripini Paul M; Tsoh Janice Y; Wetter David W; Lam Cho; de Moor Carl; Cinciripini Lynn; Baile Walter; Anderson Cheryl; Minna John D
Combined effects of venlafaxine, nicotine replacement, and brief counseling on smoking cessation.
Experimental and clinical psychopharmacology 2005;13(4):282-92.
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2005: Gazdar Adi F; Minna John D
Inhibition of EGFR signaling: all mutations are not created equal.
PLoS medicine 2005;2(11):e377.
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2005: Suzuki M; Shigematsu H; Shames D S; Sunaga N; Takahashi T; Shivapurkar N; Iizasa T; Frenkel E P; Minna J D; Fujisawa T; Gazdar A F
DNA methylation-associated inactivation of TGFbeta-related genes DRM/Gremlin, RUNX3, and HPP1 in human cancers.
British journal of cancer 2005;93(9):1029-37.
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2005: Suzuki Makoto; Shigematsu Hisayuki; Hiroshima Kenzo; Iizasa Toshihiko; Nakatani Yukio; Minna John D; Gazdar Adi F; Fujisawa Takehiko
Epidermal growth factor receptor expression status in lung cancer correlates with its mutation.
Human pathology 2005;36(10):1127-34.
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2005: Tomizawa Yoshio; Iijima Hironobu; Sunaga Noriaki; Sato Koji; Takise Atsushi; Otani Yoshimi; Tanaka Shigefumi; Suga Tatsuo; Saito Ryusei; Ishizuka Tamotsu; Dobashi Kunio; Minna John D; Nakajima Takashi; Mori Masatomo
Clinicopathologic significance of the mutations of the epidermal growth factor receptor gene in patients with non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 1):6816-22.
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2005: Janowski Bethany A; Huffman Kenneth E; Schwartz Jacob C; Ram Rosalyn; Hardy Daniel; Shames David S; Minna John D; Corey David R
Inhibiting gene expression at transcription start sites in chromosomal DNA with antigene RNAs.
Nature chemical biology 2005;1(4):216-22.
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2005: Tang Ximing; Shigematsu Hisayuki; Bekele B Nebiyou; Roth Jack A; Minna John D; Hong Waun Ki; Gazdar Adi F; Wistuba Ignacio I
EGFR tyrosine kinase domain mutations are detected in histologically normal respiratory epithelium in lung cancer patients.
Cancer research 2005;65(17):7568-72.
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2005: Zöchbauer-Müller Sabine; Fong Kwun M; Geradts Joseph; Xu Xie; Seidl Sonja; End-Pfützenreuter Adelheid; Lang György; Heller Gerwin; Zielinski Christoph C; Gazdar Adi F; Minna John D
Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation.
Oncogene 2005;24(41):6249-55.
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2005: Minna John D; Peyton Michael J; Gazdar Adi F
Gefitinib versus cetuximab in lung cancer: round one.
Journal of the National Cancer Institute 2005;97(16):1168-9.
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2005: Makarla Prakash B; Saboorian M Hossein; Ashfaq Raheela; Toyooka Kiyomi O; Toyooka Shinichi; Minna John D; Gazdar Adi F; Schorge John O
Promoter hypermethylation profile of ovarian epithelial neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5365-9.
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2005: Carbone David P; Ciernik I Frank; Kelley Michael J; Smith M Charles; Nadaf Sorena; Kavanaugh Denise; Maher V Ellen; Stipanov Michael; Contois David; Johnson Bruce E; Pendleton C David; Seifert Burkhardt; Carter Charley; Read Elizabeth J; Greenblatt Jay; Top Lois E; Kelsey Morris I; Minna John D; Berzofsky Jay A
Immunization with mutant p53- and K-ras-derived peptides in cancer patients: immune response and clinical outcome.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(22):5099-107.
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2005: Kusy Sophie; Potiron Vincent; Zeng Chan; Franklin Wilbur; Brambilla Elisabeth; Minna John; Drabkin Harry A; Roche Joëlle
Promoter characterization of Semaphorin SEMA3F, a tumor suppressor gene.
Biochimica et biophysica acta 2005;1730(1):66-76.
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2005: Zhao Xiaojun; Weir Barbara A; LaFramboise Thomas; Lin Ming; Beroukhim Rameen; Garraway Levi; Beheshti Javad; Lee Jeffrey C; Naoki Katsuhiko; Richards William G; Sugarbaker David; Chen Fei; Rubin Mark A; Jänne Pasi A; Girard Luc; Minna John; Christiani David; Li Cheng; Sellers William R; Meyerson Matthew
Homozygous deletions and chromosome amplifications in human lung carcinomas revealed by single nucleotide polymorphism array analysis.
Cancer research 2005;65(13):5561-70.
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2005: Heuzé-Vourc'h Nathalie; Liu Ming; Dalwadi Harnisha; Baratelli Felicita E; Zhu Li; Goodglick Lee; Põld Mehis; Sharma Sherven; Ramirez Ruben D; Shay Jerry W; Minna John D; Strieter Robert M; Dubinett Steven M
IL-20, an anti-angiogenic cytokine that inhibits COX-2 expression.
Biochemical and biophysical research communications 2005;333(2):470-5.
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2005: Minna John D; Dowell Jonathan
Erlotinib hydrochloride.
Nature reviews. Drug discovery 2005;Suppl():S14-5.
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2005: Henderson L-J; Coe B P; Lee E H L; Girard L; Gazdar A F; Minna J D; Lam S; MacAulay C; Lam W L
Genomic and gene expression profiling of minute alterations of chromosome arm 1p in small-cell lung carcinoma cells.
British journal of cancer 2005;92(8):1553-60.
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2005: Sekine Ikuo; Sato Mitsuo; Sunaga Noriaki; Toyooka Shinichi; Peyton Michael; Parsons Ramon; Wang Weidong; Gazdar Adi F; Minna John D
The 3p21 candidate tumor suppressor gene BAF180 is normally expressed in human lung cancer.
Oncogene 2005;24(16):2735-8.
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2005: Shigematsu Hisayuki; Takahashi Takao; Nomura Masaharu; Majmudar Kuntal; Suzuki Makoto; Lee Huei; Wistuba Ignacio I; Fong Kwun M; Toyooka Shinichi; Shimizu Nobuyoshi; Fujisawa Takehiko; Minna John D; Gazdar Adi F
Somatic mutations of the HER2 kinase domain in lung adenocarcinomas.
Cancer research 2005;65(5):1642-6.
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2005: Shigematsu Hisayuki; Lin Li; Takahashi Takao; Nomura Masaharu; Suzuki Makoto; Wistuba Ignacio I; Fong Kwun M; Lee Huei; Toyooka Shinichi; Shimizu Nobuyoshi; Fujisawa Takehiko; Feng Ziding; Roth Jack A; Herz Joachim; Minna John D; Gazdar Adi F
Clinical and biological features associated with epidermal growth factor receptor gene mutations in lung cancers.
Journal of the National Cancer Institute 2005;97(5):339-46.
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2005: Coe Bradley P; Henderson Laura-Jane; Garnis Cathie; Tsao Ming-Sound; Gazdar Adi F; Minna John; Lam Stephen; Macaulay Calum; Lam Wan L
High-resolution chromosome arm 5p array CGH analysis of small cell lung carcinoma cell lines.
Genes, chromosomes & cancer 2005;42(3):308-13.
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2005: Ji Lin; Minna John D; Roth Jack A
3p21.3 tumor suppressor cluster: prospects for translational applications.
Future oncology (London, England) 2005;1(1):79-92.
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2005: Dowell Jonathan E; Minna John D
Chasing mutations in the epidermal growth factor in lung cancer.
The New England journal of medicine 2005;352(8):830-2.
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2005: Dobbin Kevin K; Beer David G; Meyerson Matthew; Yeatman Timothy J; Gerald William L; Jacobson James W; Conley Barbara; Buetow Kenneth H; Heiskanen Mervi; Simon Richard M; Minna John D; Girard Luc; Misek David E; Taylor Jeremy M G; Hanash Samir; Naoki Katsuhiko; Hayes D Neil; Ladd-Acosta Christine; Enkemann Steven A; Viale Agnes; Giordano Thomas J
Interlaboratory comparability study of cancer gene expression analysis using oligonucleotide microarrays.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):565-72.
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2005: Kishimoto Masahiro; Kohno Takashi; Okudela Koji; Otsuka Ayaka; Sasaki Hiroki; Tanabe Chikako; Sakiyama Tokuki; Hirama Chie; Kitabayashi Issay; Minna John D; Takenoshita Seiichi; Yokota Jun
Mutations and deletions of the CBP gene in human lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):512-9.
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2005: Dowell Jonathan; Minna John D; Kirkpatrick Peter
Erlotinib hydrochloride.
Nature reviews. Drug discovery 2005;4(1):13-4.
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2005: Lewis Cheryl M; Cler Leslie R; Bu Da-Wei; Zöchbauer-Müller Sabine; Milchgrub Sara; Naftalis Elizabeth Z; Leitch A Marilyn; Minna John D; Euhus David M
Promoter hypermethylation in benign breast epithelium in relation to predicted breast cancer risk.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(1):166-72.
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2005: Amann Joseph; Kalyankrishna Shailaja; Massion Pierre P; Ohm Joyce E; Girard Luc; Shigematsu Hisayuki; Peyton Michael; Juroske Denise; Huang Yuhui; Stuart Salmon J; Kim Young H; Pollack Jonathan R; Yanagisawa Kiyoshi; Gazdar Adi; Minna John D; Kurie Jonathan M; Carbone David P
Aberrant epidermal growth factor receptor signaling and enhanced sensitivity to EGFR inhibitors in lung cancer.
Cancer research 2005;65(1):226-35.
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2005: Yap Yee Leng; Lam David C L; Luc Girard; Zhang Xue Wu; Hernandez David; Gras Robin; Wang Elaine; Chiu S W; Chung Lap Ping; Lam W K; Smith David K; Minna John D; Danchin Antoine; Wong Maria P
Conserved transcription factor binding sites of cancer markers derived from primary lung adenocarcinoma microarrays.
Nucleic acids research 2005;33(1):409-21.
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2004: Ramirez Ruben D; Sheridan Shelley; Girard Luc; Sato Mitsuo; Kim Young; Pollack Jon; Peyton Michael; Zou Ying; Kurie Jonathan M; Dimaio J Michael; Milchgrub Sara; Smith Alice L; Souza Rhonda F; Gilbey Laura; Zhang Xi; Gandia Kenia; Vaughan Melville B; Wright Woodring E; Gazdar Adi F; Shay Jerry W; Minna John D
Immortalization of human bronchial epithelial cells in the absence of viral oncoproteins.
Cancer research 2004;64(24):9027-34.
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2004: Bentires-Alj Mohamed; Paez J Guillermo; David Frank S; Keilhack Heike; Halmos Balazs; Naoki Katsuhiko; Maris John M; Richardson Andrea; Bardelli Alberto; Sugarbaker David J; Richards William G; Du Jinyan; Girard Luc; Minna John D; Loh Mignon L; Fisher David E; Velculescu Victor E; Vogelstein Bert; Meyerson Matthew; Sellers William R; Neel Benjamin G
Activating mutations of the noonan syndrome-associated SHP2/PTPN11 gene in human solid tumors and adult acute myelogenous leukemia.
Cancer research 2004;64(24):8816-20.
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2004: Dowell Jonathan E; Minna John D
The impact of epidermal-growth-factor-receptor mutations in response to lung-cancer therapy.
Nature clinical practice. Oncology 2004;1(1):2-3.
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2004: Ito Isao; Ji Lin; Tanaka Fumihiro; Saito Yuji; Gopalan Began; Branch Cynthia D; Xu Kai; Atkinson E Neely; Bekele Benjamin N; Stephens L Clifton; Minna John D; Roth Jack A; Ramesh Rajagopal
Liposomal vector mediated delivery of the 3p FUS1 gene demonstrates potent antitumor activity against human lung cancer in vivo.
Cancer gene therapy 2004;11(11):733-9.
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2004: Gazdar Adi F; Shigematsu Hisayuki; Herz Joachim; Minna John D
Mutations and addiction to EGFR: the Achilles 'heal' of lung cancers?
Trends in molecular medicine 2004;10(10):481-6.
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2004: Li Jingfeng; Wang Fuli; Haraldson Klas; Protopopov Alexey; Duh Fuh-Mei; Geil Laura; Kuzmin Igor; Minna John D; Stanbridge Eric; Braga Eleonora; Kashuba Vladimir I; Klein George; Lerman Michael I; Zabarovsky Eugene R
Functional characterization of the candidate tumor suppressor gene NPRL2/G21 located in 3p21.3C.
Cancer research 2004;64(18):6438-43.
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2004: Ivanov Sergey V; Ward Jerrold M; Tessarollo Lino; McAreavey Dorothea; Sachdev Vandana; Fananapazir Lameh; Banks Melissa K; Morris Nicole; Djurickovic Draginja; Devor-Henneman Deborah E; Wei Ming-Hui; Alvord Gregory W; Gao Boning; Richardson James A; Minna John D; Rogawski Michael A; Lerman Michael I
Cerebellar ataxia, seizures, premature death, and cardiac abnormalities in mice with targeted disruption of the Cacna2d2 gene.
The American journal of pathology 2004;165(3):1007-18.
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2004: Bailey-Wilson J E; Amos C I; Pinney S M; Petersen G M; de Andrade M; Wiest J S; Fain P; Schwartz A G; You M; Franklin W; Klein C; Gazdar A; Rothschild H; Mandal D; Coons T; Slusser J; Lee J; Gaba C; Kupert E; Perez A; Zhou X; Zeng D; Liu Q; Zhang Q; Seminara D; Minna J; Anderson M W
A major lung cancer susceptibility locus maps to chromosome 6q23-25.
American journal of human genetics 2004;75(3):460-74.
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2004: Nishizaki Masahiko; Sasaki Ji-Ichiro; Fang Bingliang; Atkinson Edward N; Minna John D; Roth Jack A; Ji Lin
Synergistic tumor suppression by coexpression of FHIT and p53 coincides with FHIT-mediated MDM2 inactivation and p53 stabilization in human non-small cell lung cancer cells.
Cancer research 2004;64(16):5745-52.
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2004: Castro-Rivera Emely; Ran Sophia; Thorpe Philip; Minna John D
Semaphorin 3B (SEMA3B) induces apoptosis in lung and breast cancer, whereas VEGF165 antagonizes this effect.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(31):11432-7.
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2004: Li Jingfeng; Wang Fuli; Protopopov Alexey; Malyukova Alena; Kashuba Vladimir; Minna John D; Lerman Michael I; Klein George; Zabarovsky Eugene
Inactivation of RASSF1C during in vivo tumor growth identifies it as a tumor suppressor gene.
Oncogene 2004;23(35):5941-9.
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2004: Dowell Jonathan E; Amirkhan Robin H; Lai Wen S; Frawley William H; Minna John D
Survival in small cell lung cancer is independent of tumor expression of VEGF and COX-2.
Anticancer research 2004;24(4):2367-73.
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2004: Weil M Ryan; Widlak Piotr; Minna John D; Garner Harold R
Global survey of chromatin accessibility using DNA microarrays.
Genome research 2004;14(7):1374-81.
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2004: Lea Jayanthi S; Ashfaq Raheela; Muneer Sabeeha; Burbee David G; Miller David S; Minna John D; Muller Carolyn Y
Understanding the mechanisms of FHIT inactivation in cervical cancer for biomarker development.
Journal of the Society for Gynecologic Investigation 2004;11(5):329-37.
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2004: Senchenko Vera N; Liu Jian; Loginov Witaly; Bazov Igor; Angeloni Debora; Seryogin Yury; Ermilova Valeria; Kazubskaya Tatiana; Garkavtseva Raisa; Zabarovska Veronika I; Kashuba Vladimir I; Kisselev Lev L; Minna John D; Lerman Michael I; Klein George; Braga Eleonora A; Zabarovsky Eugene R
Discovery of frequent homozygous deletions in chromosome 3p21.3 LUCA and AP20 regions in renal, lung and breast carcinomas.
Oncogene 2004;23(34):5719-28.
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2004: Sunaga Noriaki; Miyajima Kuniharu; Suzuki Makoto; Sato Mitsuo; White Michael A; Ramirez Ruben D; Shay Jerry W; Gazdar Adi F; Minna John D
Different roles for caveolin-1 in the development of non-small cell lung cancer versus small cell lung cancer.
Cancer research 2004;64(12):4277-85.
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2004: Minna John D; Gazdar Adi F; Sprang Stephen R; Herz Joachim
Cancer. A bull's eye for targeted lung cancer therapy.
Science (New York, N.Y.) 2004;304(5676):1458-61.
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2004: Toyooka Shinichi; Suzuki Makoto; Tsuda Toshihide; Toyooka Kiyomi O; Maruyama Riichiroh; Tsukuda Kazunori; Fukuyama Yasuro; Iizasa Toshihiko; Fujisawa Takehiko; Shimizu Nobuyoshi; Minna John D; Gazdar Adi F
Dose effect of smoking on aberrant methylation in non-small cell lung cancers.
International journal of cancer. Journal international du cancer 2004;110(3):462-4.
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2004: Wolff Nicholas C; Randle Dwight E; Egorin Merrill J; Minna John D; Ilaria Robert L
Imatinib mesylate efficiently achieves therapeutic intratumor concentrations in vivo but has limited activity in a xenograft model of small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3528-34.
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2004: Garnis Cathie; Coe Bradley; Henderson Laura-Jane; Ishkanian Adrian; Watson Spencer; Marra Marco; Minna John; Lam Stephen; MacAulay Calum; Lam Wan
Construction and optimization of chromosome arm-specific comparative genomic hybridization arrays for identifying genetic alterations in preinvasive lung cancers.
Chest 2004;125(5 Suppl):104S-5S.
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2004: Suzuki Makoto; Sunaga Noriaki; Shames David S; Toyooka Shinichi; Gazdar Adi F; Minna John D
RNA interference-mediated knockdown of DNA methyltransferase 1 leads to promoter demethylation and gene re-expression in human lung and breast cancer cells.
Cancer research 2004;64(9):3137-43.
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2004: Zhao Xiaojun; Li Cheng; Paez J Guillermo; Chin Koei; Jänne Pasi A; Chen Tzu-Hsiu; Girard Luc; Minna John; Christiani David; Leo Chris; Gray Joe W; Sellers William R; Meyerson Matthew
An integrated view of copy number and allelic alterations in the cancer genome using single nucleotide polymorphism arrays.
Cancer research 2004;64(9):3060-71.
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2004: Uno Futoshi; Sasaki Jiichiro; Nishizaki Masahiko; Carboni Giovanni; Xu Kai; Atkinson Edward N; Kondo Masashi; Minna John D; Roth Jack A; Ji Lin
Myristoylation of the fus1 protein is required for tumor suppression in human lung cancer cells.
Cancer research 2004;64(9):2969-76.
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2004: Cinciripini Paul; Wetter David; Tomlinson Gail; Tsoh Janice; De Moor Carl; Cinciripini Lynn; Minna John
The effects of the DRD2 polymorphism on smoking cessation and negative affect: evidence for a pharmacogenetic effect on mood.
Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 2004;6(2):229-39.
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2004: Kashuba Vladimir I; Li Jingfeng; Wang Fuli; Senchenko Vera N; Protopopov Alexey; Malyukova Alena; Kutsenko Alexey S; Kadyrova Elena; Zabarovska Veronika I; Muravenko Olga V; Zelenin Alexander V; Kisselev Lev L; Kuzmin Igor; Minna John D; Winberg Gösta; Ernberg Ingemar; Braga Eleonora; Lerman Michael I; Klein George; Zabarovsky Eugene R
RBSP3 (HYA22) is a tumor suppressor gene implicated in major epithelial malignancies.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4906-11.
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2004: Jänne Pasi A; Li Cheng; Zhao Xiaojun; Girard Luc; Chen Tzu-Hsiu; Minna John; Christiani David C; Johnson Bruce E; Meyerson Matthew
High-resolution single-nucleotide polymorphism array and clustering analysis of loss of heterozygosity in human lung cancer cell lines.
Oncogene 2004;23(15):2716-26.
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2004: Dowell Jonathan E; Minna John D
Cancer chemotherapy targeted at reactivating the expression of epigenetically inactivated genes.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2004;22(8):1353-5.
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2004: Lea Jayanthi S; Coleman Robert; Kurien Aleena; Schorge John O; Miller David S; Minna John D; Muller Carolyn Y
Aberrant p16 methylation is a biomarker for tobacco exposure in cervical squamous cell carcinogenesis.
American journal of obstetrics and gynecology 2004;190(3):674-9.
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2004: Sathyanarayana Ubaradka G; Maruyama Riichiroh; Padar Asha; Suzuki Makoto; Bondaruk Jolanta; Sagalowsky Arthur; Minna John D; Frenkel Eugene P; Grossman H Barton; Czerniak Bogdan; Gazdar Adi F
Molecular detection of noninvasive and invasive bladder tumor tissues and exfoliated cells by aberrant promoter methylation of laminin-5 encoding genes.
Cancer research 2004;64(4):1425-30.
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2004: Fenton Sarah L; Dallol Ashraf; Agathanggelou Angelo; Hesson Luke; Ahmed-Choudhury Jalal; Baksh Shairaz; Sardet Claude; Dammann Reinhard; Minna John D; Downward Julian; Maher Eamonn R; Latif Farida
Identification of the E1A-regulated transcription factor p120 E4F as an interacting partner of the RASSF1A candidate tumor suppressor gene.
Cancer research 2004;64(1):102-7.
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2003: Oyama Tsuksa; Sykes Kathryn F; Samli Kausar N; Minna John D; Johnston Stephen Albert; Brown Kathlynn C
Isolation of lung tumor specific peptides from a random peptide library: generation of diagnostic and cell-targeting reagents.
Cancer letters 2003;202(2):219-30.
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2003: Uchiyama Mika; Usami Noriyasu; Kondo Masashi; Mori Shoichi; Ito Masao; Ito Genshi; Yoshioka Hiromu; Imaizumi Munehisa; Ueda Yuichi; Takahashi Masahide; Minna John D; Shimokata Kaoru; Sekido Yoshitaka
Loss of heterozygosity of chromosome 12p does not correlate with KRAS mutation in non-small cell lung cancer.
International journal of cancer. Journal international du cancer 2003;107(6):962-9.
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2003: Zöchbauer-Müller Sabine; Lam Stephen; Toyooka Shinichi; Virmani Arvind K; Toyooka Kiyomi O; Seidl Sonja; Minna John D; Gazdar Adi F
Aberrant methylation of multiple genes in the upper aerodigestive tract epithelium of heavy smokers.
International journal of cancer. Journal international du cancer 2003;107(4):612-6.
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2003: Virmani Arvind; Rathi Asha; Heda Shashank; Sugio Kenji; Lewis Cheryl; Tonk Vijay; Takahashi Takashi; Roth Jack A; Minna John D; Euhus David M; Gazdar Adi F
Aberrant methylation of the cyclin D2 promoter in primary small cell, nonsmall cell lung and breast cancers.
International journal of cancer. Journal international du cancer 2003;107(3):341-5.
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2003: Padar Asha; Sathyanarayana Ubaradka G; Suzuki Makoto; Maruyama Riichiroh; Hsieh Jer-Tsong; Frenkel Eugene P; Minna John D; Gazdar Adi F
Inactivation of cyclin D2 gene in prostate cancers by aberrant promoter methylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4730-4.
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2003: Yamagata Noboru; Shyr Yu; Yanagisawa Kiyoshi; Edgerton Mary; Dang Thao P; Gonzalez Adriana; Nadaf Sorena; Larsen Paul; Roberts John R; Nesbitt Jonathan C; Jensen Roy; Levy Shawn; Moore Jason H; Minna John D; Carbone David P
A training-testing approach to the molecular classification of resected non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(13):4695-704.
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2003: Sato Mitsuo; Girard Luc; Sekine Ikuo; Sunaga Noriaki; Ramirez Ruben D; Kamibayashi Craig; Minna John D
Increased expression and no mutation of the Flap endonuclease (FEN1) gene in human lung cancer.
Oncogene 2003;22(46):7243-6.
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2003: Minna John D; Kurie Jonathan M; Jacks Tyler
A big step in the study of small cell lung cancer.
Cancer cell 2003;4(3):163-6.
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2003: Agathanggelou Angelo; Bièche Ivan; Ahmed-Choudhury Jalal; Nicke Barbara; Dammann Reinhard; Baksh Shairaz; Gao Boning; Minna John D; Downward Julian; Maher Eamonn R; Latif Farida
Identification of novel gene expression targets for the Ras association domain family 1 (RASSF1A) tumor suppressor gene in non-small cell lung cancer and neuroblastoma.
Cancer research 2003;63(17):5344-51.
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2003: Usami Noriyasu; Sekido Yoshitaka; Maeda Osamu; Yamamoto Kazuhito; Minna John D; Hasegawa Yoshinori; Yoshioka Hiromu; Imaizumi Munehisa; Ueda Yuichi; Takahashi Masahide; Shimokata Kaoru
Beta-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion.
Oncogene 2003;22(39):7923-30.
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2003: Virmani Arvind; Rathi Asha; Sugio Kenji; Sathyanarayana Ubaradka G; Toyooka Shinichi; Kischel Frank C; Tonk Vijay; Padar Asha; Takahashi Takashi; Roth Jack A; Euhus David M; Minna John D; Gazdar Adi F
Aberrant methylation of TMS1 in small cell, non small cell lung cancer and breast cancer.
International journal of cancer. Journal international du cancer 2003;106(2):198-204.
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2003: Sathyanarayana Ubaradka G; Toyooka Shinichi; Padar Asha; Takahashi Takashi; Brambilla Elizabeth; Minna John D; Gazdar Adi F
Epigenetic inactivation of laminin-5-encoding genes in lung cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2665-72.
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2003: Sasaki Shigeru; Kitagawa Yukiko; Sekido Yoshitaka; Minna John D; Kuwano Hiroyuki; Yokota Jun; Kohno Takashi
Molecular processes of chromosome 9p21 deletions in human cancers.
Oncogene 2003;22(24):3792-8.
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2003: Agathanggelou Angelo; Dallol Ashraf; Zöchbauer-Müller Sabine; Morrissey Catherine; Honorio Sofia; Hesson Luke; Martinsson Tommy; Fong Kwun M; Kuo Michael J; Yuen Po Wing; Maher Eamonn R; Minna John D; Latif Farida
Epigenetic inactivation of the candidate 3p21.3 suppressor gene BLU in human cancers.
Oncogene 2003;22(10):1580-8.
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2003: Hesson Luke; Dallol Ashraf; Minna John D; Maher Eamonn R; Latif Farida
NORE1A, a homologue of RASSF1A tumour suppressor gene is inactivated in human cancers.
Oncogene 2003;22(6):947-54.
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2003: Kurie Jonathan M; Lotan Reuben; Lee J Jack; Lee Jin Soo; Morice Rodolfo C; Liu Diane D; Xu Xiao-Chun; Khuri Fadlo R; Ro Jae Y; Hittelman Walter N; Walsh Garrett L; Roth Jack A; Minna John D; Hong Waun Ki
Treatment of former smokers with 9-cis-retinoic acid reverses loss of retinoic acid receptor-beta expression in the bronchial epithelium: results from a randomized placebo-controlled trial.
Journal of the National Cancer Institute 2003;95(3):206-14.
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2003: Carboni Giovanni L; Gao Boning; Nishizaki Masahiko; Xu Kai; Minna John D; Roth Jack A; Ji Lin
CACNA2D2-mediated apoptosis in NSCLC cells is associated with alterations of the intracellular calcium signaling and disruption of mitochondria membrane integrity.
Oncogene 2003;22(4):615-26.
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2003: Minna John D
Nicotine exposure and bronchial epithelial cell nicotinic acetylcholine receptor expression in the pathogenesis of lung cancer.
The Journal of clinical investigation 2003;111(1):31-3.
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2003: Toyooka Shinichi; Maruyama Riichiroh; Toyooka Kiyomi O; McLerran Dale; Feng Ziding; Fukuyama Yasuro; Virmani Arvind K; Zochbauer-Muller Sabine; Tsukuda Kazunori; Sugio Kenji; Shimizu Nobuyoshi; Shimizu Kenji; Lee Huei; Chen Chih-Yi; Fong Kwun M; Gilcrease Michael; Roth Jack A; Minna John D; Gazdar Adi F
Smoke exposure, histologic type and geography-related differences in the methylation profiles of non-small cell lung cancer.
International journal of cancer. Journal international du cancer 2003;103(2):153-60.
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2003: Sekido Yoshitaka; Fong Kwun M; Minna John D
Molecular genetics of lung cancer.
Annual review of medicine 2003;54():73-87.
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2002: Shivapurkar Narayan; Reddy Jyotsna; Matta Hittu; Sathyanarayana Ubaradka G; Huang C X; Toyooka Shinichi; Minna John D; Chaudhary Preet M; Gazdar Adi F
Loss of expression of death-inducing signaling complex (DISC) components in lung cancer cell lines and the influence of MYC amplification.
Oncogene 2002;21(55):8510-4.
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2002: Brose Marcia S; Volpe Patricia; Feldman Michael; Kumar Madhu; Rishi Irum; Gerrero Renee; Einhorn Eugene; Herlyn Meenhard; Minna John; Nicholson Andrew; Roth Jack A; Albelda Steven M; Davies Helen; Cox Charles; Brignell Graham; Stephens Philip; Futreal P Andrew; Wooster Richard; Stratton Michael R; Weber Barbara L
BRAF and RAS mutations in human lung cancer and melanoma.
Cancer research 2002;62(23):6997-7000.
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2002: Zhu Yong; Spitz Margaret R; Strom Sara; Tomlinson Gail E; Amos Christopher I; Minna John D; Wu Xifeng
A case-control analysis of lymphocytic chromosome 9 aberrations in lung cancer.
International journal of cancer. Journal international du cancer 2002;102(5):536-40.
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2002: Rathi Asha; Virmani Arvind K; Schorge John O; Elias Keren J; Maruyama Riichiroh; Minna John D; Mok Samuel C; Girard Luc; Fishman David A; Gazdar Adi F
Methylation profiles of sporadic ovarian tumors and nonmalignant ovaries from high-risk women.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3324-31.
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2002: Balog Robert P; de Souza Y Emi Ponce; Tang Hue M; DeMasellis Gina M; Gao Boning; Avila Adrian; Gaban Desmond J; Mittelman David; Minna John D; Luebke Kevin J; Garner Harold R
Parallel assessment of CpG methylation by two-color hybridization with oligonucleotide arrays.
Analytical biochemistry 2002;309(2):301-10.
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2002: Dallol Ashraf; Da Silva Nancy Fernandes; Viacava Paolo; Minna John D; Bieche Ivan; Maher Eamonn R; Latif Farida
SLIT2, a human homologue of the Drosophila Slit2 gene, has tumor suppressor activity and is frequently inactivated in lung and breast cancers.
Cancer research 2002;62(20):5874-80.
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2002: Zabarovsky Eugene R; Lerman Michael I; Minna John D
Tumor suppressor genes on chromosome 3p involved in the pathogenesis of lung and other cancers.
Oncogene 2002;21(45):6915-35.
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2002: Nishioka Michiho; Kohno Takashi; Tani Masachika; Yanaihara Nozomu; Tomizawa Yoshio; Otsuka Ayaka; Sasaki Shigeru; Kobayashi Keiko; Niki Toshiro; Maeshima Arafumi; Sekido Yoshitaka; Minna John D; Sone Saburo; Yokota Jun
MYO18B, a candidate tumor suppressor gene at chromosome 22q12.1, deleted, mutated, and methylated in human lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(19):12269-74.
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2002: Toyooka Kiyomi O; Toyooka Shinichi; Maitra Anirban; Feng Qinghua; Kiviat Nancy C; Smith Alice; Minna John D; Ashfaq Raheela; Gazdar Adi F
Establishment and validation of real-time polymerase chain reaction method for CDH1 promoter methylation.
The American journal of pathology 2002;161(2):629-34.
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2002: Tomizawa Yoshio; Kohno Takashi; Kondo Haruhiko; Otsuka Ayaka; Nishioka Michiho; Niki Toshiro; Yamada Tesshi; Maeshima Arafumi; Yoshimura Kimio; Saito Ryusei; Minna John D; Yokota Jun
Clinicopathological significance of epigenetic inactivation of RASSF1A at 3p21.3 in stage I lung adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2362-8.
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2002: Toyooka Shinichi; Fukuyama Yasuro; Wistuba Ignacio I; Tockman Melvyn S; Minna John D; Gazdar Adi F
Differential expression of FEZ1/LZTS1 gene in lung cancers and their cell cultures.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2292-7.
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2002: Sato Mitsuo; Horio Yoshitsugu; Sekido Yoshitaka; Minna John D; Shimokata Kaoru; Hasegawa Yoshinori
The expression of DNA methyltransferases and methyl-CpG-binding proteins is not associated with the methylation status of p14(ARF), p16(INK4a) and RASSF1A in human lung cancer cell lines.
Oncogene 2002;21(31):4822-9.
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2002: Harada Kenichi; Toyooka Shinichi; Maitra Anirban; Maruyama Riichiroh; Toyooka Kiyomi O; Timmons Charles F; Tomlinson Gail E; Mastrangelo Domenico; Hay Robert J; Minna John D; Gazdar Adi F
Aberrant promoter methylation and silencing of the RASSF1A gene in pediatric tumors and cell lines.
Oncogene 2002;21(27):4345-9.
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2002: Toyooka Shinichi; Carbone Michele; Toyooka Kiyomi O; Bocchetta Maurizio; Shivapurkar Narayan; Minna John D; Gazdar Adi F
Progressive aberrant methylation of the RASSF1A gene in simian virus 40 infected human mesothelial cells.
Oncogene 2002;21(27):4340-4.
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2002: Kuzmin Igor; Gillespie John W; Protopopov Alexei; Geil Laura; Dreijerink Koen; Yang Youfeng; Vocke Cathy D; Duh Fuh-Mei; Zabarovsky Eugene; Minna John D; Rhim Johng S; Emmert-Buck Michael R; Linehan W Marston; Lerman Michael I
The RASSF1A tumor suppressor gene is inactivated in prostate tumors and suppresses growth of prostate carcinoma cells.
Cancer research 2002;62(12):3498-502.
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2002: Shivakumar Latha; Minna John; Sakamaki Toshiyuki; Pestell Richard; White Michael A
The RASSF1A tumor suppressor blocks cell cycle progression and inhibits cyclin D1 accumulation.
Molecular and cellular biology 2002;22(12):4309-18.
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2002: Fleming Jason B; Minna John D
Inactivation of tumor suppressor genes by promoter methylation is important in the pathogenesis of pancreatic cancer.
Cancer biology & therapy 2002;1(3):297-9.
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2002: Dallol Ashraf; Forgacs Eva; Martinez Alonso; Sekido Yoshitaka; Walker Rosemary; Kishida Takeshi; Rabbitts Pamela; Maher Eamonn R; Minna John D; Latif Farida
Tumour specific promoter region methylation of the human homologue of the Drosophila Roundabout gene DUTT1 (ROBO1) in human cancers.
Oncogene 2002;21(19):3020-8.
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2002: Minna John D; Fong Kwun; Zöchbauer-Müller Sabine; Gazdar Adi F
Molecular pathogenesis of lung cancer and potential translational applications.
Cancer journal (Sudbury, Mass.) 2002;8 Suppl 1():S41-6.
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2002: Ji Lin; Nishizaki Masahiko; Gao Boning; Burbee David; Kondo Masashi; Kamibayashi Craig; Xu Kai; Yen Nancy; Atkinson E Neely; Fang Bingliang; Lerman Michael I; Roth Jack A; Minna John D
Expression of several genes in the human chromosome 3p21.3 homozygous deletion region by an adenovirus vector results in tumor suppressor activities in vitro and in vivo.
Cancer research 2002;62(9):2715-20.
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2002: Moinova Helen R; Chen Wei-Dong; Shen Lanlan; Smiraglia Dominic; Olechnowicz Joseph; Ravi Lakshmeswari; Kasturi Lakshmi; Myeroff Lois; Plass Christoph; Parsons Ramon; Minna John; Willson James K V; Green Sylvan B; Issa Jean-Pierre; Markowitz Sanford D
HLTF gene silencing in human colon cancer.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(7):4562-7.
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2002: Fong Kwun M; Minna John D
Molecular biology of lung cancer: clinical implications.
Clinics in chest medicine 2002;23(1):83-101.
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2002: Muneer Sabeeha; Ramalingam Vivek; Wyatt Robert; Schultz Roger A; Minna John D; Kamibayashi Craig
Genomic organization and mapping of the gene encoding the PP2A B56gamma regulatory subunit.
Genomics 2002;79(3):344-8.
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2002: Minna John D; Roth Jack A; Gazdar Adi F
Focus on lung cancer.
Cancer cell 2002;1(1):49-52.
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2002: Maruyama Riichiroh; Toyooka Shinichi; Toyooka Kiyomi O; Virmani Arvind K; Zöchbauer-Müller Sabine; Farinas Alfredo J; Minna John D; McConnell John; Frenkel Eugene P; Gazdar Adi F
Aberrant promoter methylation profile of prostate cancers and its relationship to clinicopathological features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):514-9.
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2002: Berman Kevin S; Verma Udit N; Harburg Gwyndolen; Minna John D; Cobb Melanie H; Gaynor Richard B
Sulindac enhances tumor necrosis factor-alpha-mediated apoptosis of lung cancer cell lines by inhibition of nuclear factor-kappaB.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):354-60.
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2002: Shivapurkar Narayan; Toyooka Shinichi; Eby Michael T; Huang Chun Xian; Sathyanarayana Ubaradka G; Cunningham H Thomas; Reddy Jyotsna L; Brambilla Elizabeth; Takahashi Takashi; Minna John D; Chaudhary Preet M; Gazdar Adi F
Differential inactivation of caspase-8 in lung cancers.
Cancer biology & therapy 2002;1(1):65-9.
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2002: Zhang Huifeng; Spitz Margaret R; Tomlinson Gail E; Schabath Matthew B; Minna John D; Wu Xifeng
Modification of lung cancer susceptibility by green tea extract as measured by the comet assay.
Cancer detection and prevention 2002;26(6):411-8.
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2002: Zöchbauer-Müller Sabine; Minna John D; Gazdar Adi F
Aberrant DNA methylation in lung cancer: biological and clinical implications.
The oncologist 2002;7(5):451-7.
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2002: Zochbauer-Muller Sabine; Gazdar Adi F; Minna John D
Molecular pathogenesis of lung cancer.
Annual review of physiology 2002;64():681-708.
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2001: Maruyama R; Toyooka S; Toyooka K O; Harada K; Virmani A K; Zöchbauer-Müller S; Farinas A J; Vakar-Lopez F; Minna J D; Sagalowsky A; Czerniak B; Gazdar A F
Aberrant promoter methylation profile of bladder cancer and its relationship to clinicopathological features.
Cancer research 2001;61(24):8659-63.
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2001: Toyooka S; Toyooka K O; Maruyama R; Virmani A K; Girard L; Miyajima K; Harada K; Ariyoshi Y; Takahashi T; Sugio K; Brambilla E; Gilcrease M; Minna J D; Gazdar A F
DNA methylation profiles of lung tumors.
Molecular cancer therapeutics 2001;1(1):61-7.
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2001: Tomizawa Y; Sekido Y; Kondo M; Gao B; Yokota J; Roche J; Drabkin H; Lerman M I; Gazdar A F; Minna J D
Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(24):13954-9.
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2001: Xu X L; Wu L C; Du F; Davis A; Peyton M; Tomizawa Y; Maitra A; Tomlinson G; Gazdar A F; Weissman B E; Bowcock A M; Baer R; Minna J D
Inactivation of human SRBC, located within the 11p15.5-p15.4 tumor suppressor region, in breast and lung cancers.
Cancer research 2001;61(21):7943-9.
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2001: Zhao H; Spitz M R; Tomlinson G E; Zhang H; Minna J D; Wu X
Gamma-radiation-induced G2 delay, apoptosis, and p53 response as potential susceptibility markers for lung cancer.
Cancer research 2001;61(21):7819-24.
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2001: Kondo M; Ji L; Kamibayashi C; Tomizawa Y; Randle D; Sekido Y; Yokota J; Kashuba V; Zabarovsky E; Kuzmin I; Lerman M; Roth J; Minna J D
Overexpression of candidate tumor suppressor gene FUS1 isolated from the 3p21.3 homozygous deletion region leads to G1 arrest and growth inhibition of lung cancer cells.
Oncogene 2001;20(43):6258-62.
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2001: Gazdar A F; Minna J D
Targeted therapies for killing tumor cells.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(18):10028-30.
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2001: Toyooka S; Pass H I; Shivapurkar N; Fukuyama Y; Maruyama R; Toyooka K O; Gilcrease M; Farinas A; Minna J D; Gazdar A F
Aberrant methylation and simian virus 40 tag sequences in malignant mesothelioma.
Cancer research 2001;61(15):5727-30.
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2001: Shigemitsu K; Sekido Y; Usami N; Mori S; Sato M; Horio Y; Hasegawa Y; Bader S A; Gazdar A F; Minna J D; Hida T; Yoshioka H; Imaizumi M; Ueda Y; Takahashi M; Shimokata K
Genetic alteration of the beta-catenin gene (CTNNB1) in human lung cancer and malignant mesothelioma and identification of a new 3p21.3 homozygous deletion.
Oncogene 2001;20(31):4249-57.
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2001: Virmani A K; Rathi A; Sathyanarayana U G; Padar A; Huang C X; Cunnigham H T; Farinas A J; Milchgrub S; Euhus D M; Gilcrease M; Herman J; Minna J D; Gazdar A F
Aberrant methylation of the adenomatous polyposis coli (APC) gene promoter 1A in breast and lung carcinomas.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1998-2004.
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2001: Maitra A; Wistuba I I; Washington C; Virmani A K; Ashfaq R; Milchgrub S; Gazdar A F; Minna J D
High-resolution chromosome 3p allelotyping of breast carcinomas and precursor lesions demonstrates frequent loss of heterozygosity and a discontinuous pattern of allele loss.
The American journal of pathology 2001;159(1):119-30.
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2001: Dreijerink K; Braga E; Kuzmin I; Geil L; Duh F M; Angeloni D; Zbar B; Lerman M I; Stanbridge E J; Minna J D; Protopopov A; Li J; Kashuba V; Klein G; Zabarovsky E R
The candidate tumor suppressor gene, RASSF1A, from human chromosome 3p21.3 is involved in kidney tumorigenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7504-9.
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2001: Toyooka K O; Toyooka S; Virmani A K; Sathyanarayana U G; Euhus D M; Gilcrease M; Minna J D; Gazdar A F
Loss of expression and aberrant methylation of the CDH13 (H-cadherin) gene in breast and lung carcinomas.
Cancer research 2001;61(11):4556-60.
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2001: Burbee D G; Forgacs E; Zöchbauer-Müller S; Shivakumar L; Fong K; Gao B; Randle D; Kondo M; Virmani A; Bader S; Sekido Y; Latif F; Milchgrub S; Toyooka S; Gazdar A F; Lerman M I; Zabarovsky E; White M; Minna J D
Epigenetic inactivation of RASSF1A in lung and breast cancers and malignant phenotype suppression.
Journal of the National Cancer Institute 2001;93(9):691-9.
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2001: Zöchbauer-Müller S; Fong K M; Maitra A; Lam S; Geradts J; Ashfaq R; Virmani A K; Milchgrub S; Gazdar A F; Minna J D
5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.
Cancer research 2001;61(9):3581-5.
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2001: Agathanggelou A; Honorio S; Macartney D P; Martinez A; Dallol A; Rader J; Fullwood P; Chauhan A; Walker R; Shaw J A; Hosoe S; Lerman M I; Minna J D; Maher E R; Latif F
Methylation associated inactivation of RASSF1A from region 3p21.3 in lung, breast and ovarian tumours.
Oncogene 2001;20(12):1509-18.
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2001: Ramesh R; Saeki T; Templeton N S; Ji L; Stephens L C; Ito I; Wilson D R; Wu Z; Branch C D; Minna J D; Roth J A
Successful treatment of primary and disseminated human lung cancers by systemic delivery of tumor suppressor genes using an improved liposome vector.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;3(3):337-50.
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2001: Forgacs E; Wren J D; Kamibayashi C; Kondo M; Xu X L; Markowitz S; Tomlinson G E; Muller C Y; Gazdar A F; Garner H R; Minna J D
Searching for microsatellite mutations in coding regions in lung, breast, ovarian and colorectal cancers.
Oncogene 2001;20(8):1005-9.
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2001: Zöchbauer-Müller S; Fong K M; Virmani A K; Geradts J; Gazdar A F; Minna J D
Aberrant promoter methylation of multiple genes in non-small cell lung cancers.
Cancer research 2001;61(1):249-55.
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2001: Forgacs E; Zöchbauer-Müller S; Oláh E; Minna J D
Molecular genetic abnormalities in the pathogenesis of human lung cancer.
Pathology oncology research : POR 2001;7(1):6-13.
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2000: Pertsemlidis A; Pande A; Miller B; Schilling P; Wei M H; Lerman M I; Minna J D; Garner H R; Mittelman D
PANORAMA: an integrated Web-based sequence analysis tool and its role in gene discovery.
Genomics 2000;70(3):300-6.
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2000: Zöchbauer-Müller S; Minna J D
The biology of lung cancer including potential clinical applications.
Chest surgery clinics of North America 2000;10(4):691-708.
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2000: Brekken R A; Overholser J P; Stastny V A; Waltenberger J; Minna J D; Thorpe P E
Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice.
Cancer research 2000;60(18):5117-24.
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2000: Girard L; Zöchbauer-Müller S; Virmani A K; Gazdar A F; Minna J D
Genome-wide allelotyping of lung cancer identifies new regions of allelic loss, differences between small cell lung cancer and non-small cell lung cancer, and loci clustering.
Cancer research 2000;60(17):4894-906.
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2000: Dang T P; Gazdar A F; Virmani A K; Sepetavec T; Hande K R; Minna J D; Roberts J R; Carbone D P
Chromosome 19 translocation, overexpression of Notch3, and human lung cancer.
Journal of the National Cancer Institute 2000;92(16):1355-7.
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2000: Virmani A K; Rathi A; Zöchbauer-Müller S; Sacchi N; Fukuyama Y; Bryant D; Maitra A; Heda S; Fong K M; Thunnissen F; Minna J D; Gazdar A F
Promoter methylation and silencing of the retinoic acid receptor-beta gene in lung carcinomas.
Journal of the National Cancer Institute 2000;92(16):1303-7.
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2000: Wren J D; Forgacs E; Fondon J W; Pertsemlidis A; Cheng S Y; Gallardo T; Williams R S; Shohet R V; Minna J D; Garner H R
Repeat polymorphisms within gene regions: phenotypic and evolutionary implications.
American journal of human genetics 2000;67(2):345-56.
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2000: Wistuba I I; Tomlinson G E; Behrens C; Virmani A; Geradts J; Blum J L; Minna J D; Gazdar A F
Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome.
Genes, chromosomes & cancer 2000;28(4):359-69.
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2000: Wistuba I I; Berry J; Behrens C; Maitra A; Shivapurkar N; Milchgrub S; Mackay B; Minna J D; Gazdar A F
Molecular changes in the bronchial epithelium of patients with small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(7):2604-10.
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2000: Sato M; Sekido Y; Horio Y; Takahashi M; Saito H; Minna J D; Shimokata K; Hasegawa Y
Infrequent mutation of the hBUB1 and hBUBR1 genes in human lung cancer.
Japanese journal of cancer research : Gann 2000;91(5):504-9.
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2000: Gao B; Sekido Y; Maximov A; Saad M; Forgacs E; Latif F; Wei M H; Lerman M; Lee J H; Perez-Reyes E; Bezprozvanny I; Minna J D
Functional properties of a new voltage-dependent calcium channel alpha(2)delta auxiliary subunit gene (CACNA2D2).
The Journal of biological chemistry 2000;275(16):12237-42.
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2000: Liu C X; Musco S; Lisitsina N M; Forgacs E; Minna J D; Lisitsyn N A
LRP-DIT, a putative endocytic receptor gene, is frequently inactivated in non-small cell lung cancer cell lines.
Cancer research 2000;60(7):1961-7.
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2000: Wistuba I I; Behrens C; Virmani A K; Mele G; Milchgrub S; Girard L; Fondon J W; Garner H R; McKay B; Latif F; Lerman M I; Lam S; Gazdar A F; Minna J D
High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints.
Cancer research 2000;60(7):1949-60.
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2000: Geradts J; Fong K M; Zimmerman P V; Minna J D
Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features.
British journal of cancer 2000;82(6):1191-7.
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2000: Hamada K; Kohno T; Takahashi M; Yamazaki M; Yamazaki M; Tashiro H; Sugawara C; Ohwada S; Sekido Y; Minna J D; Yokota J
Two regions of homozygous deletion clusters at chromosome band 9p21 in human lung cancer.
Genes, chromosomes & cancer 2000;27(3):308-18.
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1999: Fong K M; Sekido Y; Minna J D
Molecular pathogenesis of lung cancer.
The Journal of thoracic and cardiovascular surgery 1999;118(6):1136-52.
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1999: Park I W; Wistuba I I; Maitra A; Milchgrub S; Virmani A K; Minna J D; Gazdar A F
Multiple clonal abnormalities in the bronchial epithelium of patients with lung cancer.
Journal of the National Cancer Institute 1999;91(21):1863-8.
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1999: Shivapurkar N; Sood S; Wistuba I I; Virmani A K; Maitra A; Milchgrub S; Minna J D; Gazdar A F
Multiple regions of chromosome 4 demonstrating allelic losses in breast carcinomas.
Cancer research 1999;59(15):3576-80.
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1999: Flowers L C; Wistuba I I; Scurry J; Muller C Y; Ashfaq R; Miller D S; Minna J D; Gazdar A F
Genetic changes during the multistage pathogenesis of human papillomavirus positive and negative vulvar carcinomas.
Journal of the Society for Gynecologic Investigation 1999;6(4):213-21.
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1999: Ji L; Fang B; Yen N; Fong K; Minna J D; Roth J A
Induction of apoptosis and inhibition of tumorigenicity and tumor growth by adenovirus vector-mediated fragile histidine triad (FHIT) gene overexpression.
Cancer research 1999;59(14):3333-9.
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1999: Wang S S; Virmani A; Gazdar A F; Minna J D; Evans G A
Refined mapping of two regions of loss of heterozygosity on chromosome band 11q23 in lung cancer.
Genes, chromosomes & cancer 1999;25(2):154-9.
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1999: Wistuba I I; Bryant D; Behrens C; Milchgrub S; Virmani A K; Ashfaq R; Minna J D; Gazdar A F
Comparison of features of human lung cancer cell lines and their corresponding tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(5):991-1000.
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1999: Wistuba I I; Behrens C; Virmani A K; Milchgrub S; Syed S; Lam S; Mackay B; Minna J D; Gazdar A F
Allelic losses at chromosome 8p21-23 are early and frequent events in the pathogenesis of lung cancer.
Cancer research 1999;59(8):1973-9.
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1999: Wu W; Kemp B L; Proctor M L; Gazdar A F; Minna J D; Hong W K; Mao L
Expression of DMBT1, a candidate tumor suppressor gene, is frequently lost in lung cancer.
Cancer research 1999;59(8):1846-51.
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1999: Geradts J; Fong K M; Zimmerman P V; Maynard R; Minna J D
Correlation of abnormal RB, p16ink4a, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(4):791-800.
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1999: Wistuba I I; Behrens C; Milchgrub S; Bryant D; Hung J; Minna J D; Gazdar A F
Sequential molecular abnormalities are involved in the multistage development of squamous cell lung carcinoma.
Oncogene 1999;18(3):643-50.
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1999: Shivapurkar N; Virmani A K; Wistuba I I; Milchgrub S; Mackay B; Minna J D; Gazdar A F
Deletions of chromosome 4 at multiple sites are frequent in malignant mesothelioma and small cell lung carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):17-23.
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1998: Wistuba I I; Behrens C; Milchgrub S; Syed S; Ahmadian M; Virmani A K; Kurvari V; Cunningham T H; Ashfaq R; Minna J D; Gazdar A F
Comparison of features of human breast cancer cell lines and their corresponding tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(12):2931-8.
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1998: Gazdar A F; Kurvari V; Virmani A; Gollahon L; Sakaguchi M; Westerfield M; Kodagoda D; Stasny V; Cunningham H T; Wistuba I I; Tomlinson G; Tonk V; Ashfaq R; Leitch A M; Minna J D; Shay J W
Characterization of paired tumor and non-tumor cell lines established from patients with breast cancer.
International journal of cancer. Journal international du cancer 1998;78(6):766-74.
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1998: Sundaresan V; Chung G; Heppell-Parton A; Xiong J; Grundy C; Roberts I; James L; Cahn A; Bench A; Douglas J; Minna J; Sekido Y; Lerman M; Latif F; Bergh J; Li H; Lowe N; Ogilvie D; Rabbitts P
Homozygous deletions at 3p12 in breast and lung cancer.
Oncogene 1998;17(13):1723-9.
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1998: Wang S S; Esplin E D; Li J L; Huang L; Gazdar A; Minna J; Evans G A
Alterations of the PPP2R1B gene in human lung and colon cancer.
Science (New York, N.Y.) 1998;282(5387):284-7.
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1998: Forgacs E; Biesterveld E J; Sekido Y; Fong K; Muneer S; Wistuba I I; Milchgrub S; Brezinschek R; Virmani A; Gazdar A F; Minna J D
Mutation analysis of the PTEN/MMAC1 gene in lung cancer.
Oncogene 1998;17(12):1557-65.
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1998: Oh Y; Proctor M L; Fan Y H; Su L K; Hong W K; Fong K M; Sekido Y S; Gazdar A F; Minna J D; Mao L
TSG101 is not mutated in lung cancer but a shortened transcript is frequently expressed in small cell lung cancer.
Oncogene 1998;17(9):1141-8.
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1998: Sekido Y; Fong K M; Minna J D
Progress in understanding the molecular pathogenesis of human lung cancer.
Biochimica et biophysica acta 1998;1378(1):F21-59.
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1998: Tomlinson G E; Chen T T; Stastny V A; Virmani A K; Spillman M A; Tonk V; Blum J L; Schneider N R; Wistuba I I; Shay J W; Minna J D; Gazdar A F
Characterization of a breast cancer cell line derived from a germ-line BRCA1 mutation carrier.
Cancer research 1998;58(15):3237-42.
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1998: Sekido Y; Ahmadian M; Wistuba I I; Latif F; Bader S; Wei M H; Duh F M; Gazdar A F; Lerman M I; Minna J D
Cloning of a breast cancer homozygous deletion junction narrows the region of search for a 3p21.3 tumor suppressor gene.
Oncogene 1998;16(24):3151-7.
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1998: Fondon J W; Mele G M; Brezinschek R I; Cummings D; Pande A; Wren J; O'Brien K M; Kupfer K C; Wei M H; Lerman M; Minna J D; Garner H R
Computerized polymorphic marker identification: experimental validation and a predicted human polymorphism catalog.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7514-9.
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1998: Sundaresan V; Roberts I; Bateman A; Bankier A; Sheppard M; Hobbs C; Xiong J; Minna J; Latif F; Lerman M; Rabbitts P
The DUTT1 gene, a novel NCAM family member is expressed in developing murine neural tissues and has an unusually broad pattern of expression.
Molecular and cellular neurosciences 1998;11(1-2):29-35.
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1998: Wistuba I I; Behrens C; Milchgrub S; Virmani A K; Jagirdar J; Thomas B; Ioachim H L; Litzky L A; Brambilla E M; Minna J D; Gazdar A F
Comparison of molecular changes in lung cancers in HIV-positive and HIV-indeterminate subjects.
JAMA : the journal of the American Medical Association 1998;279(19):1554-9.
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1998: Wu X; Zhao Y; Honn S E; Tomlinson G E; Minna J D; Hong W K; Spitz M R
Benzo[a]pyrene diol epoxide-induced 3p21.3 aberrations and genetic predisposition to lung cancer.
Cancer research 1998;58(8):1605-8.
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1998: Virmani A K; Fong K M; Kodagoda D; McIntire D; Hung J; Tonk V; Minna J D; Gazdar A F
Allelotyping demonstrates common and distinct patterns of chromosomal loss in human lung cancer types.
Genes, chromosomes & cancer 1998;21(4):308-19.
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1998: Muller C Y; O'Boyle J D; Fong K M; Wistuba I I; Biesterveld E; Ahmadian M; Miller D S; Gazdar A F; Minna J D
Abnormalities of fragile histidine triad genomic and complementary DNAs in cervical cancer: association with human papillomavirus type.
Journal of the National Cancer Institute 1998;90(6):433-9.
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1997: Wistuba I I; Lam S; Behrens C; Virmani A K; Fong K M; LeRiche J; Samet J M; Srivastava S; Minna J D; Gazdar A F
Molecular damage in the bronchial epithelium of current and former smokers.
Journal of the National Cancer Institute 1997;89(18):1366-73.
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1997: Ong S T; Fong K M; Bader S A; Minna J D; Le Beau M M; McKeithan T W; Rassool F V
Precise localization of the FHIT gene to the common fragile site at 3p14.2 (FRA3B) and characterization of homozygous deletions within FRA3B that affect FHIT transcription in tumor cell lines.
Genes, chromosomes & cancer 1997;20(1):16-23.
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1997: Ahmadian M; Wistuba I I; Fong K M; Behrens C; Kodagoda D R; Saboorian M H; Shay J; Tomlinson G E; Blum J; Minna J D; Gazdar A F
Analysis of the FHIT gene and FRA3B region in sporadic breast cancer, preneoplastic lesions, and familial breast cancer probands.
Cancer research 1997;57(17):3664-8.
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1997: Wistuba I I; Montellano F D; Milchgrub S; Virmani A K; Behrens C; Chen H; Ahmadian M; Nowak J A; Muller C; Minna J D; Gazdar A F
Deletions of chromosome 3p are frequent and early events in the pathogenesis of uterine cervical carcinoma.
Cancer research 1997;57(15):3154-8.
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1997: Fong K M; Biesterveld E J; Virmani A; Wistuba I; Sekido Y; Bader S A; Ahmadian M; Ong S T; Rassool F V; Zimmerman P V; Giaccone G; Gazdar A F; Minna J D
FHIT and FRA3B 3p14.2 allele loss are common in lung cancer and preneoplastic bronchial lesions and are associated with cancer-related FHIT cDNA splicing aberrations.
Cancer research 1997;57(11):2256-67.
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1997: Bansal A; Ramirez R D; Minna J D
Mutation analysis of the coding sequences of MEK-1 and MEK-2 genes in human lung cancer cell lines.
Oncogene 1997;14(10):1231-4.
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1997: Latif F; Duh F M; Bader S; Sekido Y; Li H; Geil L; Zbar B; Minna J D; Lerman M I
The human homolog of the rodent immediate early response genes, PC4 and TIS7, resides in the lung cancer tumor suppressor gene region on chromosome 3p21.
Human genetics 1997;99(3):334-41.
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1997: Kim S K; Ro J Y; Kemp B L; Lee J S; Kwon T J; Fong K M; Sekido Y; Minna J D; Hong W K; Mao L
Identification of three distinct tumor suppressor loci on the short arm of chromosome 9 in small cell lung cancer.
Cancer research 1997;57(3):400-3.
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1997: Vuitch F; Sekido Y; Fong K; Mackay B; Minna J D; Gazdar A F
Neuroendocrine tumors of the lung. Pathology and molecular biology.
Chest surgery clinics of North America 1997;7(1):21-47.
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1996: Minna J D; Gazdar A F
Translational research comes of age.
Nature medicine 1996;2(9):974-5.
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1996: Sekido Y; Bader S; Latif F; Chen J Y; Duh F M; Wei M H; Albanesi J P; Lee C C; Lerman M I; Minna J D
Human semaphorins A(V) and IV reside in the 3p21.3 small cell lung cancer deletion region and demonstrate distinct expression patterns.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4120-5.
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1996: Wei M H; Latif F; Bader S; Kashuba V; Chen J Y; Duh F M; Sekido Y; Lee C C; Geil L; Kuzmin I; Zabarovsky E; Klein G; Zbar B; Minna J D; Lerman M I
Construction of a 600-kilobase cosmid clone contig and generation of a transcriptional map surrounding the lung cancer tumor suppressor gene (TSG) locus on human chromosome 3p21.3: progress toward the isolation of a lung cancer TSG.
Cancer research 1996;56(7):1487-92.
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1996: Shaw G L; Gazdar A F; Phelps R; Steinberg S M; Linnoila R I; Johnson B E; Oie H K; Russell E K; Ghosh B C; Pass H I; Minna J D; Mulshine J L; Ihde D C
Correlation of in vitro drug sensitivity testing results with response to chemotherapy and survival: comparison of non-small cell lung cancer and small cell lung cancer.
Journal of cellular biochemistry. Supplement 1996;24():173-85.
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1996: Phelps R M; Johnson B E; Ihde D C; Gazdar A F; Carbone D P; McClintock P R; Linnoila R I; Matthews M J; Bunn P A; Carney D; Minna J D; Mulshine J L
NCI-Navy Medical Oncology Branch cell line data base.
Journal of cellular biochemistry. Supplement 1996;24():32-91.
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1995: Ciernik I F; Krayenbühl Ciernik B H; Cockerell C J; Minna J D; Gazdar A F; Carbone D P
Expression of transforming growth factor beta and transforming growth factor beta receptors on AIDS-associated Kaposi's sarcoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(10):1119-24.
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1995: Kishimoto Y; Sugio K; Hung J Y; Virmani A K; McIntire D D; Minna J D; Gazdar A F
Allele-specific loss in chromosome 9p loci in preneoplastic lesions accompanying non-small-cell lung cancers.
Journal of the National Cancer Institute 1995;87(16):1224-9.
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1995: Hung J; Kishimoto Y; Sugio K; Virmani A; McIntire D D; Minna J D; Gazdar A F
Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.
JAMA : the journal of the American Medical Association 1995;273(24):1908.
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1995: Sekido Y; Pass H I; Bader S; Mew D J; Christman M F; Gazdar A F; Minna J D
Neurofibromatosis type 2 (NF2) gene is somatically mutated in mesothelioma but not in lung cancer.
Cancer research 1995;55(6):1227-31.
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1995: Hung J; Kishimoto Y; Sugio K; Virmani A; McIntire D D; Minna J D; Gazdar A F
Allele-specific chromosome 3p deletions occur at an early stage in the pathogenesis of lung carcinoma.
JAMA : the journal of the American Medical Association 1995;273(7):558-63.
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1994: Carbone D P; Mitsudomi T; Chiba I; Piantadosi S; Rusch V; Nowak J A; McIntire D; Slamon D; Gazdar A; Minna J
p53 immunostaining positivity is associated with reduced survival and is imperfectly correlated with gene mutations in resected non-small cell lung cancer. A preliminary report of LCSG 871.
Chest 1994;106(6 Suppl):377S-381S.
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1994: Maneckjee R; Minna J D
Opioids induce while nicotine suppresses apoptosis in human lung cancer cells.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(10):1033-40.
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1994: Sekido Y; Bader S A; Carbone D P; Johnson B E; Minna J D
Molecular analysis of the HuD gene encoding a paraneoplastic encephalomyelitis antigen in human lung cancer cell lines.
Cancer research 1994;54(18):4988-92.
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1994: Sekido Y; Bader S; Latif F; Gnarra J R; Gazdar A F; Linehan W M; Zbar B; Lerman M I; Minna J D
Molecular analysis of the von Hippel-Lindau disease tumor suppressor gene in human lung cancer cell lines.
Oncogene 1994;9(6):1599-604.
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1994: Sang B C; Chen J Y; Minna J; Barbosa M S
Distinct regions of p53 have a differential role in transcriptional activation and repression functions.
Oncogene 1994;9(3):853-9.
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1994: Mulshine J L; Johnson B E; Gazdar A F; Shaw G L; Kramer B S; Mitsudomi T; Minna J D; Pass H; Phelps R; Ghosh B
Integrated clinical and basic studies related to circumventing non-small cell lung cancer drug resistance.
Lung cancer (Amsterdam, Netherlands) 1994;10 Suppl 1():S73-81.
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1994: Gazdar A F; Bader S; Hung J; Kishimoto Y; Sekido Y; Sugio K; Virmani A; Fleming J; Carbone D P; Minna J D
Molecular genetic changes found in human lung cancer and its precursor lesions.
Cold Spring Harbor symposia on quantitative biology 1994;59():565-72.
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1993: Winter S F; Sekido Y; Minna J D; McIntire D; Johnson B E; Gazdar A F; Carbone D P
Antibodies against autologous tumor cell proteins in patients with small-cell lung cancer: association with improved survival.
Journal of the National Cancer Institute 1993;85(24):2012-8.
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1993: Geradts J; Chen J Y; Russell E K; Yankaskas J R; Nieves L; Minna J D
Human lung cancer cell lines exhibit resistance to retinoic acid treatment.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(10):799-809.
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1993: Chen J Y; Funk W D; Wright W E; Shay J W; Minna J D
Heterogeneity of transcriptional activity of mutant p53 proteins and p53 DNA target sequences.
Oncogene 1993;8(8):2159-66.
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1993: Broers J L; Viallet J; Jensen S M; Pass H; Travis W D; Minna J D; Linnoila R I
Expression of c-myc in progenitor cells of the bronchopulmonary epithelium and in a large number of non-small cell lung cancers.
American journal of respiratory cell and molecular biology 1993;9(1):33-43.
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1993: Yanuck M; Carbone D P; Pendleton C D; Tsukui T; Winter S F; Minna J D; Berzofsky J A
A mutant p53 tumor suppressor protein is a target for peptide-induced CD8+ cytotoxic T-cells.
Cancer research 1993;53(14):3257-61.
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1993: Olopade O I; Buchhagen D L; Malik K; Sherman J; Nobori T; Bader S; Nau M M; Gazdar A F; Minna J D; Diaz M O
Homozygous loss of the interferon genes defines the critical region on 9p that is deleted in lung cancers.
Cancer research 1993;53(10 Suppl):2410-5.
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1992: Winter S F; Minna J D; Johnson B E; Takahashi T; Gazdar A F; Carbone D P
Development of antibodies against p53 in lung cancer patients appears to be dependent on the type of p53 mutation.
Cancer research 1992;52(15):4168-74.
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1992: Kaur G; Viallet J; Laborda J; Blair O; Gazdar A F; Minna J D; Sausville E A
Growth inhibition by cholera toxin of human lung carcinoma cell lines: correlation with GM1 ganglioside expression.
Cancer research 1992;52(12):3340-6.
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1992: Maneckjee R; Minna J D
Biologically active MK-801 and SKF-10,047 binding sites distinct from those in rat brain are expressed on human lung cancer cells.
Molecular biology of the cell 1992;3(6):613-9.
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1992: Bodner S M; Minna J D; Jensen S M; D'Amico D; Carbone D; Mitsudomi T; Fedorko J; Buchhagen D L; Nau M M; Gazdar A F
Expression of mutant p53 proteins in lung cancer correlates with the class of p53 gene mutation.
Oncogene 1992;7(4):743-9.
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1992: D'Amico D; Carbone D P; Johnson B E; Meltzer S J; Minna J D
Polymorphic sites within the MCC and APC loci reveal very frequent loss of heterozygosity in human small cell lung cancer.
Cancer research 1992;52(7):1996-9.
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1992: Broers J L; Jensen S M; Travis W D; Pass H; Whitsett J A; Singh G; Katyal S L; Gazdar A F; Minna J D; Linnoila R I
Expression of surfactant associated protein-A and Clara cell 10 kilodalton mRNA in neoplastic and non-neoplastic human lung tissue as detected by in situ hybridization.
Laboratory investigation; a journal of technical methods and pathology 1992;66(3):337-46.
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1992: Maneckjee R; Minna J D
Nonconventional opioid binding sites mediate growth inhibitory effects of methadone on human lung cancer cells.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(4):1169-73.
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1992: Mitsudomi T; Steinberg S M; Nau M M; Carbone D; D'Amico D; Bodner S; Oie H K; Linnoila R I; Mulshine J L; Minna J D
p53 gene mutations in non-small-cell lung cancer cell lines and their correlation with the presence of ras mutations and clinical features.
Oncogene 1992;7(1):171-80.
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1992: Carbone D P; Minna J D
The molecular genetics of lung cancer.
Advances in internal medicine 1992;37():153-71.
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1991: Mitsudomi T; Steinberg S M; Oie H K; Mulshine J L; Phelps R; Viallet J; Pass H; Minna J D; Gazdar A F
ras gene mutations in non-small cell lung cancers are associated with shortened survival irrespective of treatment intent.
Cancer research 1991;51(18):4999-5002.
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1991: Mitsudomi T; Viallet J; Mulshine J L; Linnoila R I; Minna J D; Gazdar A F
Mutations of ras genes distinguish a subset of non-small-cell lung cancer cell lines from small-cell lung cancer cell lines.
Oncogene 1991;6(8):1353-62.
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1991: Kim J H; Takahashi T; Chiba I; Park J G; Birrer M J; Roh J K; De Lee H; Kim J P; Minna J D; Gazdar A F
Occurrence of p53 gene abnormalities in gastric carcinoma tumors and cell lines.
Journal of the National Cancer Institute 1991;83(13):938-43.
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1991: Whang-Peng J; Knutsen T; Gazdar A; Steinberg S M; Oie H; Linnoila I; Mulshine J; Nau M; Minna J D
Nonrandom structural and numerical chromosome changes in non-small-cell lung cancer.
Genes, chromosomes & cancer 1991;3(3):168-88.
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1991: Dosaka-Akita H; Rosenberg R K; Minna J D; Birrer M J
A complex pattern of translational initiation and phosphorylation in L-myc proteins.
Oncogene 1991;6(3):371-8.
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1990: Viallet J; Sharoni Y; Frucht H; Jensen R T; Minna J D; Sausville E A
Cholera toxin inhibits signal transduction by several mitogens and the in vitro growth of human small-cell lung cancer.
The Journal of clinical investigation 1990;86(6):1904-12.
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1990: Curiel D T; Buchhagen D L; Chiba I; D'Amico D; Takahashi T; Minna J D
A chemical mismatch cleavage method useful for the detection of point mutations in the p53 gene in lung cancer.
American journal of respiratory cell and molecular biology 1990;3(5):405-11.
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1990: Takahashi T; D'Amico D; Chiba I; Buchhagen D L; Minna J D
Identification of intronic point mutations as an alternative mechanism for p53 inactivation in lung cancer.
The Journal of clinical investigation 1990;86(1):363-9.
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1990: Maneckjee R; Minna J D
Opioid and nicotine receptors affect growth regulation of human lung cancer cell lines.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(9):3294-8.
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1990: Johnson B E; Grayson J; Makuch R W; Linnoila R I; Anderson M J; Cohen M H; Glatstein E; Minna J D; Ihde D C
Ten-year survival of patients with small-cell lung cancer treated with combination chemotherapy with or without irradiation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1990;8(3):396-401.
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1990: Viallet J; Minna J D
Dominant oncogenes and tumor suppressor genes in the pathogenesis of lung cancer.
American journal of respiratory cell and molecular biology 1990;2(3):225-32.
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1990: Gazdar A F; Steinberg S M; Russell E K; Linnoila R I; Oie H K; Ghosh B C; Cotelingam J D; Johnson B E; Minna J D; Ihde D C
Correlation of in vitro drug-sensitivity testing results with response to chemotherapy and survival in extensive-stage small cell lung cancer: a prospective clinical trial.
Journal of the National Cancer Institute 1990;82(2):117-24.
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1989: Schütte J; Viallet J; Nau M; Segal S; Fedorko J; Minna J
jun-B inhibits and c-fos stimulates the transforming and trans-activating activities of c-jun.
Cell 1989;59(6):987-97.
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1989: Takahashi T; Nau M M; Chiba I; Birrer M J; Rosenberg R K; Vinocour M; Levitt M; Pass H; Gazdar A F; Minna J D
p53: a frequent target for genetic abnormalities in lung cancer.
Science (New York, N.Y.) 1989;246(4929):491-4.
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1989: Minna J D
Genetic events in the pathogenesis of lung cancer.
Chest 1989;96(1 Suppl):17S-23S.
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1989: Schütte J; Minna J D; Birrer M J
Deregulated expression of human c-jun transforms primary rat embryo cells in cooperation with an activated c-Ha-ras gene and transforms rat-1a cells as a single gene.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(7):2257-61.
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1989: Birrer M J; Minna J D
Genetic changes in the pathogenesis of lung cancer.
Annual review of medicine 1989;40():305-17.
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1989: Minna J D; Schütte J; Viallet J; Thomas F; Kaye F J; Takahashi T; Nau M; Whang-Peng J; Birrer M; Gazdar A F
Transcription factors and recessive oncogenes in the pathogenesis of human lung cancer.
International journal of cancer. Supplement = Journal international du cancer. Supplement 1989;4():32-4.
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1989: Viallet J; Minna J D
Gastrin-releasing peptide (GRP, mammalian bombesin) in the pathogenesis of lung cancer.
Progress in growth factor research 1989;1(2):89-97.
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1988: De Greve J; Battey J; Fedorko J; Birrer M; Evan G; Kaye F; Sausville E; Minna J
The human L-myc gene encodes multiple nuclear phosphoproteins from alternatively processed mRNAs.
Molecular and cellular biology 1988;8(10):4381-8.
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1988: Whang-Peng J; Lee E C; Minna J D; Abeloff M D; Bradley E C; Young R C; Longo D L
Deletion of 3(p14p23) in secondary erythroleukemia arising in long-term survivors of small cell lung cancer.
Journal of the National Cancer Institute 1988;80(15):1253-5.
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1988: Johnson B E; Sakaguchi A Y; Gazdar A F; Minna J D; Burch D; Marshall A; Naylor S L
Restriction fragment length polymorphism studies show consistent loss of chromosome 3p alleles in small cell lung cancer patients' tumors.
The Journal of clinical investigation 1988;82(2):502-7.
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1988: Krystal G; Birrer M; Way J; Nau M; Sausville E; Thompson C; Minna J; Battey J
Multiple mechanisms for transcriptional regulation of the myc gene family in small-cell lung cancer.
Molecular and cellular biology 1988;8(8):3373-81.
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1988: Nakanishi Y; Mulshine J L; Kasprzyk P G; Natale R B; Maneckjee R; Avis I; Treston A M; Gazdar A F; Minna J D; Cuttitta F
Insulin-like growth factor-I can mediate autocrine proliferation of human small cell lung cancer cell lines in vitro.
The Journal of clinical investigation 1988;82(1):354-9.
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1988: Gu J; Linnoila R I; Seibel N L; Gazdar A F; Minna J D; Brooks B J; Hollis G F; Kirsch I R
A study of myc-related gene expression in small cell lung cancer by in situ hybridization.
The American journal of pathology 1988;132(1):13-7.
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1988: Birrer M J; Minna J D
Molecular genetics of lung cancer.
Seminars in oncology 1988;15(3):226-35.
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1988: Carmichael J; Mitchell J B; DeGraff W G; Gamson J; Gazdar A F; Johnson B E; Glatstein E; Minna J D
Chemosensitivity testing of human lung cancer cell lines using the MTT assay.
British journal of cancer 1988;57(6):540-7.
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1988: Birrer M J; Segal S; DeGreve J S; Kaye F; Sausville E A; Minna J D
L-myc cooperates with ras to transform primary rat embryo fibroblasts.
Molecular and cellular biology 1988;8(6):2668-73.
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1988: Kaye F; Battey J; Nau M; Brooks B; Seifter E; De Greve J; Birrer M; Sausville E; Minna J
Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing.
Molecular and cellular biology 1988;8(1):186-95.
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1988: Mulshine J L; Avis I; Treston A M; Mobley C; Kaspryzyk P; Carrasquillo J A; Larson S M; Nakanishi Y; Merchant B; Minna J D
Clinical use of a monoclonal antibody to bombesin-like peptide in patients with lung cancer.
Annals of the New York Academy of Sciences 1988;547():360-72.
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1987: Park J G; Kramer B S; Steinberg S M; Carmichael J; Collins J M; Minna J D; Gazdar A F
Chemosensitivity testing of human colorectal carcinoma cell lines using a tetrazolium-based colorimetric assay.
Cancer research 1987;47(22):5875-9.
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1987: Bunn P A; Lichter A S; Makuch R W; Cohen M H; Veach S R; Matthews M J; Anderson A J; Edison M; Glatstein E; Minna J D
Chemotherapy alone or chemotherapy with chest radiation therapy in limited stage small cell lung cancer. A prospective, randomized trial.
Annals of internal medicine 1987;106(5):655-62.
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1986: Seifter E J; Bunn P A; Cohen M H; Makuch R W; Dunnick N R; Javadpour N; Bensimon H; Eddy J L; Minna J D; Ihde D C
A trial of combination chemotherapy followed by hormonal therapy for previously untreated metastatic carcinoma of the prostate.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1986;4(9):1365-73.
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1986: Winkler C F; Sausville E A; Ihde D C; Fischmann A B; Schechter G P; Kumar P P; Nibhanupdi J R; Minna J D; Makuch R W; Eddy J L
Combined modality treatment of cutaneous T cell lymphoma: results of a 6-year follow-up.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1986;4(7):1094-100.
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1986: Johnson B E; Ihde D C; Matthews M J; Bunn P A; Zabell A; Makuch R W; Johnston-Early A; Cohen M H; Glatstein E; Minna J D
Non-small-cell lung cancer. Major cause of late mortality in patients with small cell lung cancer.
The American journal of medicine 1986;80(6):1103-10.
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1986: Streicher H Z; Cuttitta F; Buckenmeyer G K; Kawamura H; Minna J; Berzofsky J A
Mapping the idiotopes of a monoclonal anti-myoglobin antibody with syngeneic monoclonal anti-idiotypic antibodies: detection of a common idiotope.
Journal of immunology (Baltimore, Md. : 1950) 1986;136(3):1007-14.
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1986: Nau M M; Brooks B J; Carney D N; Gazdar A F; Battey J F; Sausville E A; Minna J D
Human small-cell lung cancers show amplification and expression of the N-myc gene.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(4):1092-6.
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1986: Minna J D; Battey J F; Brooks B J; Cuttitta F; Gazdar A F; Johnson B E; Ihde D C; Lebacq-Verheyden A M; Mulshine J; Nau M M
Molecular genetic analysis reveals chromosomal deletion, gene amplification, and autocrine growth factor production in the pathogenesis of human lung cancer.
Cold Spring Harbor symposia on quantitative biology 1986;51 Pt 2():843-53.
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1986: Minna J D; Battey J F; Birrer M; Brooks B J; Cuttitta F; DeGreve J; Gazdar A F; Johnson B E; Nau M M; Sausville E A
Chromosomal deletion, gene amplification, alternative processing, and autocrine growth factor production in the pathogenesis of human lung cancer.
Princess Takamatsu symposia 1986;17():109-22.
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1985: Nau M M; Brooks B J; Battey J; Sausville E; Gazdar A F; Kirsch I R; McBride O W; Bertness V; Hollis G F; Minna J D
L-myc, a new myc-related gene amplified and expressed in human small cell lung cancer.
Nature 1985;318(6041):69-73.
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1985: Cuttitta F; Carney D N; Mulshine J; Moody T W; Fedorko J; Fischler A; Minna J D
Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer.
Nature 1985;316(6031):823-6.
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1985: Lichter A S; Bunn P A; Ihde D C; Cohen M H; Makuch R W; Carney D N; Johnston-Early A; Minna J D; Glatstein E
The role of radiation therapy in the treatment of small cell lung cancer.
Cancer 1985;55(9 Suppl):2163-75.
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1985: Cuttitta F; Carney D N; Mulshine J; Moody T W; Fedorko J; Fischler A; Minna J D
Autocrine growth factors in human small cell lung cancer.
Cancer surveys 1985;4(4):707-27.
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1984: Mulshine J L; Makuch R W; Johnston-Early A; Matthews M J; Carney D N; Ihde D C; Cohen M H; Bates H R; Dunnick N R; Minna J D
Diagnosis and significance of liver metastases in small cell carcinoma of the lung.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1984;2(7):733-41.
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1983: Brower M; Ihde D C; Johnston-Early A; Bunn P A; Cohen M H; Carney D N; Makuch R W; Matthews M J; Radice P A; Minna J D
Treatment of extensive stage small cell bronchogenic carcinoma. Effects of variation in intensity of induction chemotherapy.
The American journal of medicine 1983;75(6):993-1000.
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1983: Brower M; Carney D N; Ihde D C; Eddy J; Bunn P A; Cohen M H; Pelsor F R; Matthews M J; Minna J D
High-dose methotrexate with leucovorin rescue in patients with unresectable non-small cell carcinoma of the lung.
Cancer 1983;52(10):1778-82.
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1983: Johnston-Early A; Cohen M H; Fossieck B E; Harwood S; Ihde D C; Bunn P A; Matthews M J; Minna J D; Makuch R
Delayed hypersensitivity skin testing as a prognostic indicator in patients with small cell lung cancer.
Cancer 1983;52(8):1395-400.
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1982: Radice P A; Matthews M J; Ihde D C; Gazdar A F; Carney D N; Bunn P A; Cohen M H; Fossieck B E; Makuch R W; Minna J D
The clinical behavior of "mixed" small cell/large cell bronchogenic carcinoma compared to "pure" small cell subtypes.
Cancer 1982;50(12):2894-902.
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1982: Berzofsky J A; Buckenmeyer G K; Hicks G; Gurd F R; Feldmann R J; Minna J
Topographic antigenic determinants recognized by monoclonal antibodies to sperm whale myoglobin.
The Journal of biological chemistry 1982;257(6):3189-98.
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1982: Bradley E C; Schechter G P; Matthews M J; Whang-Peng J; Cohen M H; Bunn P A; Ihde D C; Minna J D
Erythroleukemia and other hematologic complications of intensive therapy in long-term survivors of small cell lung cancer.
Cancer 1982;49(2):221-3.
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1980: Berzofsky J A; Hicks G; Fedorko J; Minna J
Properties of monoclonal antibodies specific for determinants of a protein antigen, myoglobin.
The Journal of biological chemistry 1980;255(23):11188-91.
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1980: Johnston-Early A; Cohen M H; Minna J D; Paxton L M; Fossieck B E; Ihde D C; Bunn P A; Matthews M J; Makuch R
Smoking abstinence and small cell lung cancer survival. An association.
JAMA : the journal of the American Medical Association 1980;244(19):2175-9.
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1980: Bunn P A; Huberman M S; Whang-Peng J; Schechter G P; Guccion J G; Matthews M J; Gazdar A F; Dunnick N R; Fischmann A B; Ihde D C; Cohen M H; Fossieck B; Minna J D
Prospective staging evaluation of patients with cutaneous T-cell lymphomas. Demonstration of a high frequency of extracutaneous dissemination.
Annals of internal medicine 1980;93(2):223-30.
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1980: Huberman M S; Bunn P A; Matthews M J; Ihde D C; Gazdar A F; Cohen M H; Minna J D
Hepatic involvement in the cutaneous T-cell lymphomas: results of percutaneous biopsy and peritoneoscopy.
Cancer 1980;45(7):1683-8.
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