FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Nigel Minton

Research Profile

Chemicals & Drugs

Procedures

Cloning, Molecular

Concepts & Ideas

Genes & Molecular Sequences

Living Beings

Anatomy

Spores, Bacterial

Co-author Network

Publications

TOP 3
Sara Jabbari; Nigel P Minton; Elisabeth Steiner; Klaus Winzer; John T Heap; John R King
The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum.
Yen Kuan Ng; Sheryl Philip; Stephen T Cartman; Mark M Collery; Anne Collignon; Muhammad Ehsaan; Claire Janoir; Nigel P Minton
Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles.
Clare M Cooksley; Stephanie Redl; Hengzheng Wang; Klaus Winzer; Ying Zhang; Nigel P Minton
Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Nigel Minton (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Sara Jabbari; Nigel P Minton; Elisabeth Steiner; Klaus Winzer; John T Heap; John R King
The putative influence of the agr operon upon survival mechanisms used by Clostridium acetobutylicum.
Mathematical biosciences 2013;243(2):223-39.
2013: Yen Kuan Ng; Sheryl Philip; Stephen T Cartman; Mark M Collery; Anne Collignon; Muhammad Ehsaan; Claire Janoir; Nigel P Minton
Expanding the repertoire of gene tools for precise manipulation of the Clostridium difficile genome: allelic exchange using pyrE alleles.
PloS one 2013;8(2):e56051.
2012: Clare M Cooksley; Stephanie Redl; Hengzheng Wang; Klaus Winzer; Ying Zhang; Nigel P Minton
Targeted mutagenesis of the Clostridium acetobutylicum acetone-butanol-ethanol fermentation pathway.
Metabolic engineering 2012;14(6):630-41.
2012: Sarah A Kuehne; Nigel P Minton
ClosTron-mediated engineering of Clostridium.
Bioengineered 2012;3(4):247-54.
2012: John T Heap; Stephen T Cartman; Clare M Cooksley; Muhammad Ehsaan; Yen-Kuan Ng; Klaus Winzer; Nigel P Minton
Integration of DNA into bacterial chromosomes from plasmids without a counter-selection marker.
Nucleic acids research 2012;40(8):e59.
2012: Daniela Heeg; David A Burns; Stephen T Cartman; Nigel P Minton
Spores of Clostridium difficile clinical isolates display a diverse germination response to bile salts.
PloS one 2012;7(2):e32381.
2011: Sarah A Kuehne; Stephen T Cartman; Nigel P Minton
Both, toxin A and toxin B, are important in Clostridium difficile infection.
Gut microbes 2011;2(4):252-5.
2011: Elisabeth Steiner; Angel E Dago; Danielle I Young; John T Heap; Nigel P Minton; James A Hoch; Michael Young
Multiple orphan histidine kinases interact directly with Spo0A to control the initiation of endospore formation in Clostridium acetobutylicum.
Molecular microbiology 2011;80(3):641-54.
2011: David A Burns; Stephen T Cartman; Daniela Heeg; Nigel P Minton
Reconsidering the sporulation characteristics of hypervirulent Clostridium difficile BI/NAP1/027.
PloS one 2011;6(9):e24894.
2011: Sarah A Kuehne; Stephen T Cartman; Clare M Cooksley; John T Heap; Nigel P Minton
ClosTron-mediated engineering of Clostridium.
Methods in molecular biology (Clifton, N.J.) 2011;765():389-407.
2010: David A Burns; John T Heap; Nigel P Minton
The diverse sporulation characteristics of Clostridium difficile clinical isolates are not associated with type.
Anaerobe 2010;16(6):618-22.
2010: David A Burns; John T Heap; Nigel P Minton
Clostridium difficile spore germination: an update.
Research in microbiology 2010;161(9):730-4.
2010: Sarah A Kuehne; Stephen T Cartman; John T Heap; Michelle L Kelly; Alan Cockayne; Nigel P Minton
The role of toxin A and toxin B in Clostridium difficile infection.
Nature 2010;467(7316):711-3.
2010: Stephen T Cartman; John T Heap; Sarah A Kuehne; Alan Cockayne; Nigel P Minton
The emergence of 'hypervirulence' in Clostridium difficile.
International journal of medical microbiology : IJMM 2010;300(6):387-95.
2010: Clare M Cooksley; Ian J Davis; Klaus Winzer; Weng C Chan; Michael W Peck; Nigel P Minton
Regulation of neurotoxin production and sporulation by a Putative agrBD signaling system in proteolytic Clostridium botulinum.
Applied and environmental microbiology 2010;76(13):4448-60.
2010: Stephen T Cartman; Nigel P Minton
A mariner-based transposon system for in vivo random mutagenesis of Clostridium difficile.
Applied and environmental microbiology 2010;76(4):1103-9.
2010: David A Burns; John T Heap; Nigel P Minton
SleC is essential for germination of Clostridium difficile spores in nutrient-rich medium supplemented with the bile salt taurocholate.
Journal of bacteriology 2010;192(3):657-64.
2010: John T Heap; Stephen T Cartman; Sarah A Kuehne; Clare Cooksley; Nigel P Minton
ClosTron-targeted mutagenesis.
Methods in molecular biology (Clifton, N.J.) 2010;646():165-82.
2010: Gemma L Marsden; Ian J Davis; Victoria J Wright; Mohammed Sebaihia; Ed J Kuijper; Nigel P Minton
Array comparative hybridisation reveals a high degree of similarity between UK and European clinical isolates of hypervirulent Clostridium difficile.
BMC genomics 2010;11():389.
2010: John T Heap; Sarah A Kuehne; Muhammad Ehsaan; Stephen T Cartman; Clare M Cooksley; Jamie C Scott; Nigel P Minton
The ClosTron: Mutagenesis in Clostridium refined and streamlined.
Journal of microbiological methods 2010;80(1):49-55.
2009: John T Heap; Oliver J Pennington; Stephen T Cartman; Nigel P Minton
A modular system for Clostridium shuttle plasmids.
Journal of microbiological methods 2009;78(1):79-85.
2007: Majed M AbuKhader; John Heap; Cristina I De Matteis; Stephen W Doughty; Nigel P Minton; Max Paoli
Crystallization and preliminary X-ray characterization of the Bacillus amyloliquefaciens YwrO enzyme.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 9):746-50.
2007: John T Heap; Oliver J Pennington; Stephen T Cartman; Glen P Carter; Nigel P Minton
The ClosTron: a universal gene knock-out system for the genus Clostridium.
Journal of microbiological methods 2007;70(3):452-64.
2007: Roy R Chaudhuri; Chuan-Peng Ren; Leah Desmond; Gemma A Vincent; Nigel J Silman; John K Brehm; Michael J Elmore; michael hudson; Mats Forsman; Karen E Isherwood; Darina Gurycová; Nigel P Minton; Richard Titball; Mark J Pallen; Richard Vipond
Genome sequencing shows that European isolates of Francisella tularensis subspecies tularensis are almost identical to US laboratory strain Schu S4.
PloS one 2007;2(4):e352.
2006: Jan Theys; O Pennington; Ludwig Dubois; Gill M Anlezark; T Vaughan; Asferd Mengesha; Willy Landuyt; Jozef Anne; P J Burke; P Dûrre; Bradly G Wouters; Nigel P Minton; Philippe Lambin
Repeated cycles of Clostridium-directed enzyme prodrug therapy result in sustained antitumour effects in vivo.
British journal of cancer 2006;95(9):1212-9.
2006: Julia Vipond; Richard Vipond; Emma Allen-Vercoe; Simon O Clark; Graham J Hatch; Karen E Gooch; Joanna Bacon; Toby Hampshire; Helen Shuttleworth; Nigel P Minton; Karen Blake; Ann Williams; Philip D Marsh
Selection of novel TB vaccine candidates and their evaluation as DNA vaccines against aerosol challenge.
Vaccine 2006;24(37-39):6340-50.
2005: Majed AbuKhader; John Heap; Cristina De Matteis; Barrie Kellam; Stephen W Doughty; Nigel P Minton; Max Paoli
Binding of the anticancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex.
Journal of medicinal chemistry 2005;48(24):7714-9.
2005: Glen P Carter; Des Purdy; Paul Williams; Nigel P Minton
Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling system.
Journal of medical microbiology 2005;54(Pt 2):119-27.
2005: Surinder K Sharma; R Barbara Pedley; Jeetendra Bhatia; Geoffrey M Boxer; Ethaar El-Emir; Uzma Qureshi; Berend Tolner; Helen Lowe; N Paul Michael; Nigel P Minton; Richard H J Begent; Kerry A Chester
Sustained tumor regression of human colorectal cancer xenografts using a multifunctional mannosylated fusion protein in antibody-directed enzyme prodrug therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 1):814-25.
2004: Pierre Nioche; Vladimir Berka; Julia Vipond; Nigel P Minton; Ah-Lim Tsai; C.S. Raman
Femtomolar sensitivity of a NO sensor from Clostridium botulinum.
Science (New York, N.Y.) 2004;306(5701):1550-3.
2004: Astrid Mayer; Surinder K Sharma; Berend Tolner; Nigel P Minton; Des Purdy; P Amlot; G Tharakan; Richard H J Begent; Kerry A Chester
Modifying an immunogenic epitope on a therapeutic protein: a step towards an improved system for antibody-directed enzyme prodrug therapy (ADEPT).
British journal of cancer 2004;90(12):2402-10.
2004: Nigel P Minton; Glen Carter; Mike Herbert; Triona O'keeffe; Des Purdy; Michael J Elmore; Anna Ostrowski; Oliver Pennington; Ian Davis
The development of Clostridium difficile genetic systems.
Anaerobe 2004;10(2):75-84.
2003: Mike Herbert; Triona A O'Keeffe; Des Purdy; Michael J Elmore; Nigel P Minton
Gene transfer into Clostridium difficile CD630 and characterisation of its methylase genes.
FEMS microbiology letters 2003;229(1):103-10.
2003: Nigel P Minton
Clostridia in cancer therapy.
Nature reviews. Microbiology 2003;1(3):237-42.
2003: Adam Roberts; Claire Hennequin; Michael J Elmore; Anne Collignon; Tuomo Karjalainen; Nigel P Minton; Peter Mullany
Development of an integrative vector for the expression of antisense RNA in Clostridium difficile.
Journal of microbiological methods 2003;55(3):617-24.
2002: Des Purdy; Triona A T O'Keeffe; Michael J Elmore; Mike Herbert; Anne McLeod; Monika Bokori-Brown; Anna Ostrowski; Nigel P Minton
Conjugative transfer of clostridial shuttle vectors from Escherichia coli to Clostridium difficile through circumvention of the restriction barrier.
Molecular microbiology 2002;46(2):439-52.
2002: Daniel I R Spencer; Lynda Robson; Des Purdy; Nick R Whitelegg; N Paul Michael; Jeetendra Bhatia; Surinder K Sharma; Anthony R Rees; Nigel P Minton; Richard H J Begent; Kerry A Chester
A strategy for mapping and neutralizing conformational immunogenic sites on protein therapeutics.
Proteomics 2002;2(3):271-9.
2002: Gill M Anlezark; Thomas Vaughan; Elizabeth Fashola-Stone; N Paul Michael; Heather Murdoch; Meg A Sims; Simon Stubbs; Stuart Wigley; Nigel P Minton
Bacillus amyloliquefaciens orthologue of Bacillus subtilis ywrO encodes a nitroreductase enzyme which activates the prodrug CB 1954.
Microbiology (Reading, England) 2002;148(Pt 1):297-306.
2000: Sayed Goda; A F Sharman; M Yates; N Mann; N Carr; Nigel P Minton; John K Brehm
Recombinant expression analysis of natural and synthetic bovine alpha-casein in Escherichia coli.
Applied microbiology and biotechnology 2000;54(5):671-6.
2000: J L Holley; Michael J Elmore; M Mauchline; Nigel P Minton; Richard Titball
Cloning, expression and evaluation of a recombinant sub-unit vaccine against Clostridium botulinum type F toxin.
Vaccine 2000;19(2-3):288-97.
2000: T O Davis; I Henderson; John K Brehm; Nigel P Minton
Development of a transformation and gene reporter system for group II, non-proteolytic Clostridium botulinum type B strains.
Journal of molecular microbiology and biotechnology 2000;2(1):59-69.
1998: Sayed Goda; O Eisa; M Akhter; Nigel P Minton
Molecular analysis of the malR gene of Clostridium butyricum NCIMB 7423, a member of the LacI-GalR family of repressor proteins.
FEMS microbiology letters 1998;165(1):193-200.
1998: Martin Tangney; John K Brehm; Nigel P Minton; Wilfrid J Mitchell
A gene system for glucitol transport and metabolism in Clostridium beijerinckii NCIMB 8052.
Applied and environmental microbiology 1998;64(5):1612-9.
1997: Sayed Goda; O Eissa; M Akhtar; Nigel P Minton
Molecular analysis of a Clostridium butyricum NCIMB 7423 gene encoding 4-alpha-glucanotransferase and characterization of the recombinant enzyme produced in Escherichia coli.
Microbiology (Reading, England) 1997;143 ( Pt 10)():3287-94.
1996: Jonathan Reizer; Wilfrid J Mitchell; Nigel P Minton; J Brehm; A Reizer; Milton H Saier
Proposed topology of the glucitol permeases of Escherichia coli and Clostridium acetobutylicum.
Current microbiology 1996;33(5):331-3.
1996: I Henderson; S M Whelan; T O Davis; Nigel P Minton
Genetic characterisation of the botulinum toxin complex of Clostridium botulinum strain NCTC 2916.
FEMS microbiology letters 1996;140(2-3):151-8.
1996: N P Michael; Kerry A Chester; R G Melton; L Robson; W Nicholas; J A Boden; R Barbara Pedley; Richard H J Begent; R F Sherwood; Nigel P Minton
In vitro and in vivo characterisation of a recombinant carboxypeptidase G2::anti-CEA scFv fusion protein.
Immunotechnology : an international journal of immunological engineering 1996;2(1):47-57.
1996: M E Fox; M J Lemmon; M L Mauchline; T O Davis; Amato J Giaccia; Nigel P Minton; J M Brown
Anaerobic bacteria as a delivery system for cancer gene therapy: in vitro activation of 5-fluorocytosine by genetically engineered clostridia.
Gene therapy 1996;3(2):173-8.
1995: J A Bridgewater; Caroline J Springer; Richard J Knox; Nigel P Minton; N P Michael; Mary K Collins
Expression of the bacterial nitroreductase enzyme in mammalian cells renders them selectively sensitive to killing by the prodrug CB1954.
European journal of cancer (Oxford, England : 1990) 1995;31A(13-14):2362-70.
1995: Nigel P Minton; M L Mauchline; M J Lemmon; J K Brehm; M Fox; N P Michael; Amato J Giaccia; J M Brown
Chemotherapeutic tumour targeting using clostridial spores.
FEMS microbiology reviews 1995;17(3):357-64.
1995: Sayed Goda; Nigel P Minton
A simple procedure for gel electrophoresis and northern blotting of RNA.
Nucleic acids research 1995;23(16):3357-8.
1995: Nigel P Minton
Molecular genetics of clostridial neurotoxins.
Current topics in microbiology and immunology 1995;195():161-94.
1994: N P Michael; J K Brehm; G M Anlezark; Nigel P Minton
Physical characterisation of the Escherichia coli B gene encoding nitroreductase and its over-expression in Escherichia coli K12.
FEMS microbiology letters 1994;124(2):195-202.
1994: J D Faulkner; J G Anson; M F Tuite; Nigel P Minton
High-level expression of the phenylalanine ammonia lyase-encoding gene from Rhodosporidium toruloides in Saccharomyces cerevisiae and Escherichia coli using a bifunctional expression system.
Gene 1994;143(1):13-20.
1993: J D Oultram; I D Burr; M J Elmore; Nigel P Minton
Cloning and sequence analysis of the genes encoding phosphotransbutyrylase and butyrate kinase from Clostridium acetobutylicum NCIMB 8052.
Gene 1993;131(1):107-12.
1993: J D Faulkner; Nigel P Minton
Rapid small-scale isolation of mRNA from whole yeast cells.
BioTechniques 1993;14(5):718-20.
1993: J D Oultram; M Loughlin; R Walmsley; S M Gunnery; Nigel P Minton
The nucleotide sequence of genes involved in the leucine biosynthetic pathway of Clostridium pasteurianum.
DNA sequence : the journal of DNA sequencing and mapping 1993;4(2):105-11.
1992: Sayed Goda; Nigel P Minton; Nigel P Botting; David Gani
Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding beta-methylaspartase and characterization of the recombinant protein.
Biochemistry 1992;31(44):10747-56.
1992: S M Whelan; M J Elmore; N J Bodsworth; J K Brehm; T Atkinson; Nigel P Minton
Molecular cloning of the Clostridium botulinum structural gene encoding the type B neurotoxin and determination of its entire nucleotide sequence.
Applied and environmental microbiology 1992;58(8):2345-54.
1992: J K Brehm; A Pennock; H M Bullman; M Young; J D Oultram; Nigel P Minton
Physical characterization of the replication origin of the cryptic plasmid pCB101 isolated from Clostridium butyricum NCIB 7423.
Plasmid 1992;28(1):1-13.
1992: S P Chambers; J K Brehm; N P Michael; T Atkinson; Nigel P Minton
Physical characterisation and over-expression of the Bacillus caldotenax superoxide dismutase gene.
FEMS microbiology letters 1992;70(3):277-84.
1992: S M Whelan; M J Elmore; N J Bodsworth; T Atkinson; Nigel P Minton
The complete amino acid sequence of the Clostridium botulinum type-E neurotoxin, derived by nucleotide-sequence analysis of the encoding gene.
European journal of biochemistry / FEBS 1992;204(2):657-67.
1991: J K Brehm; S P Chambers; K J Brown; T Atkinson; Nigel P Minton
Molecular cloning and nucleotide sequence determination of the Bacillus stearothermophilus NCA 1503 superoxide dismutase gene and its overexpression in Escherichia coli.
Applied microbiology and biotechnology 1991;36(3):358-63.
1991: T J Swinfield; L Jannière; S D Ehrlich; Nigel P Minton
Characterization of a region of the Enterococcus faecalis plasmid pAM beta 1 which enhances the segregational stability of pAM beta 1-derived cloning vectors in Bacillus subtilis.
Plasmid 1991;26(3):209-21.
1990: D J Nicholls; T K Sundaram; T Atkinson; Nigel P Minton
Cloning and nucleotide sequences of the mdh and sucD genes from Thermus aquaticus B.
FEMS microbiology letters 1990;58(1):7-14.
1990: D E Thompson; J K Brehm; J D Oultram; T J Swinfield; Clifford C Shone; T Atkinson; J Melling; Nigel P Minton
The complete amino acid sequence of the Clostridium botulinum type A neurotoxin, deduced by nucleotide sequence analysis of the encoding gene.
European journal of biochemistry / FEBS 1990;189(1):73-81.
1990: Nigel P Minton; T J Swinfield; J K Brehm; J D Oultram
The gram-positive cloning vector pBD64 arose by a 1844 bp deletion of pC194 derived DNA.
Nucleic acids research 1990;18(6):1651.
1990: T J Swinfield; J D Oultram; D E Thompson; J K Brehm; Nigel P Minton
Physical characterisation of the replication region of the Streptococcus faecalis plasmid pAM beta 1.
Gene 1990;87(1):79-90.
1989: Nigel P Minton; P J Whitehead; T Atkinson; Harry J Gilbert
Nucleotide sequence of an Erwinia chrysanthemi gene encoding shikimate kinase.
Nucleic acids research 1989;17(4):1769.
1988: D J Nicholls; T K Sundaram; T Atkinson; Nigel P Minton
Nucleotide sequence of the succinyl-CoA synthetase alpha-subunit from Thermus aquaticus B.
Nucleic acids research 1988;16(20):9858.
1988: Nigel P Minton; J D Oultram
Host: vector systems for gene cloning in Clostridium.
Microbiological sciences 1988;5(10):310-5.
1988: J D Oultram; H Peck; J K Brehm; D E Thompson; T J Swinfield; Nigel P Minton
Introduction of genes for leucine biosynthesis from Clostridium pasteurianum into C. acetobutylicum by cointegrate conjugal transfer.
Molecular & general genetics : MGG 1988;214(1):177-9.
1988: S P Chambers; S E Prior; D A Barstow; Nigel P Minton
The pMTL nic- cloning vectors. I. Improved pUC polylinker regions to facilitate the use of sonicated DNA for nucleotide sequencing.
Gene 1988;68(1):139-49.
1988: Nigel P Minton; J D Oultram; J K Brehm; T Atkinson
The replication proteins of plasmids pE194 and pLS1 have N-terminal homology.
Nucleic acids research 1988;16(7):3101.
1987: J Brehm; G Salmond; Nigel P Minton
Sequence of the adenine methylase gene of the Streptococcus faecalis plasmid pAM beta 1.
Nucleic acids research 1987;15(7):3177.
1987: J G Anson; Harry J Gilbert; J D Oram; Nigel P Minton
Complete nucleotide sequence of the Rhodosporidium toruloides gene coding for phenylalanine ammonia-lyase.
Gene 1987;58(2-3):189-99.
1986: D A Barstow; Anthony R Clarke; W N Chia; Dale B Wigley; A F Sharman; J John Holbrook; T Atkinson; Nigel P Minton
Cloning, expression and complete nucleotide sequence of the Bacillus stearothermophilus L-lactate dehydrogenase gene.
Gene 1986;46(1):47-55.
1986: D A Barstow; A F Sharman; T Atkinson; Nigel P Minton
Cloning and complete nucleotide sequence of the Bacillus stearothermophilus tryptophanyl tRNA synthetase gene.
Gene 1986;46(1):37-45.
1986: Nigel P Minton; H M Bullman; M D Scawen; T Atkinson; Harry J Gilbert
Nucleotide sequence of the Erwinia chrysanthemi NCPPB 1066 L-asparaginase gene.
Gene 1986;46(1):25-35.
1986: Harry J Gilbert; R Blazek; H M Bullman; Nigel P Minton
Cloning and expression of the Erwinia chrysanthemi asparaginase gene in Escherichia coli and Erwinia carotovora.
Journal of general microbiology 1986;132(1):151-60.
1985: L E Clarke; R F Gibson; R F Sherwood; Nigel P Minton
Expression of the Pseudomonas gene coding for carboxypeptidase G2 in Saccharomyces cerevisiae.
Journal of general microbiology 1985;131(4):897-903.
1985: Nigel P Minton; L E Clarke
Identification of the promoter of the Pseudomonas gene coding for carboxypeptidase G2.
Journal of molecular and applied genetics 1985;3(1):26-35.
1984: Nigel P Minton; T Atkinson; C J Bruton; R F Sherwood
The complete nucleotide sequence of the Pseudomonas gene coding for carboxypeptidase G2.
Gene 1984;31(1-3):31-8.
1983: Nigel P Minton; T Atkinson; R F Sherwood
Molecular cloning of the Pseudomonas carboxypeptidase G2 gene and its expression in Escherichia coli and Pseudomonas putida.
Journal of bacteriology 1983;156(3):1222-7.