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Will Minuth

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Will W Minuth; Lucia Denk
Interstitial interfaces show marked differences in regenerating tubules, matured tubules, and the renal stem/progenitor cell niche.
Will W Minuth; Lucia Denk
Supportive development of functional tissues for biomedical research using the MINUSHEET® perfusion system.
Will W Minuth; Lucia Denk
Illustration of extensive extracellular matrix at the epithelial-mesenchymal interface within the renal stem/progenitor cell niche.

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All Publications

2012: Will W Minuth; Lucia Denk
Interstitial interfaces show marked differences in regenerating tubules, matured tubules, and the renal stem/progenitor cell niche.
Journal of biomedical materials research. Part A 2012;100(5):1115-25.
2012: Will W Minuth; Lucia Denk
Supportive development of functional tissues for biomedical research using the MINUSHEET® perfusion system.
Clinical and translational medicine 2012;1(1):22.
2012: Will W Minuth; Lucia Denk
Illustration of extensive extracellular matrix at the epithelial-mesenchymal interface within the renal stem/progenitor cell niche.
BMC clinical pathology 2012;12():16.
2011: Will W Minuth; Christian Miess; Lucia Denk; Anne Glashauser
Peculiarities of the extracellular matrix in the interstitium of the renal stem/progenitor cell niche.
Histochemistry and cell biology 2011;136(3):321-34.
2010: Will W Minuth; Lucia Denk; Anne Glashauser
Cell and drug delivery therapeutics for controlled renal parenchyma regeneration.
Advanced drug delivery reviews 2010;62(7-8):841-54.
2010: C Miess; A Glashauser; Lucia Denk; U deVries; Will W Minuth
The interface between generating renal tubules and a polyester fleece in comparison to the interstitium of the developing kidney.
Annals of biomedical engineering 2010;38(6):2197-209.
2010: Will W Minuth; Lucia Denk; Anne Glashauser
A modular culture system for the generation of multiple specialized tissues.
Biomaterials 2010;31(11):2945-54.
2009: Anne Roessger; Lucia Denk; Will W Minuth
Potential of stem/progenitor cell cultures within polyester fleeces to regenerate renal tubules.
Biomaterials 2009;30(22):3723-32.
2009: Will W Minuth; Lucia Denk; Christine Meese; Reinhard Rachel; Anne Roessger
Ultrastructural insights in the interface between generated renal tubules and a polyester interstitium.
Langmuir : the ACS journal of surfaces and colloids 2009;25(8):4621-7.
2008: Annette Blattmann; Lucia Denk; Raimund Strehl; Hayo Castrop; Will W Minuth
The formation of pores in the basal lamina of regenerated renal tubules.
Biomaterials 2008;29(18):2749-56.
2008: Will W Minuth; Lucia Denk; Hayo Castrop
Generation of tubular superstructures by piling of renal stem/progenitor cells.
Tissue engineering. Part C, Methods 2008;14(1):3-13.
2007: Will W Minuth; Lucia Denk; Kanghong Hu
The role of polyester interstitium and aldosterone during structural development of renal tubules in serum-free medium.
Biomaterials 2007;28(30):4418-28.
2007: Kanghong Hu; Lucia Denk; Uwe de Vries; Will W Minuth
Chemically defined medium environment for the development of renal stem cells into tubules.
Biotechnology journal 2007;2(8):992-5.
2007: Will W Minuth; Raimund Strehl
Technical and theoretical considerations about gradient perfusion culture for epithelia used in tissue engineering, biomaterial testing and pharmaceutical research.
Biomedical materials (Bristol, England) 2007;2(2):R1-R11.
2007: Sabine Heber; Lucia Denk; Kanghong Hu; Will W Minuth
Modulating the development of renal tubules growing in serum-free culture medium at an artificial interstitium.
Tissue engineering 2007;13(2):281-92.
2005: Will W Minuth; Lucia Denk; Sabine Heber
Growth of embryonic renal parenchyme at the interphase of a polyester artificial interstitium.
Biomaterials 2005;26(33):6588-98.
2005: Raimund Strehl; Tommi Tallheden; Eva Sjögren-Jansson; Will W Minuth; Anders Lindahl
Long-term maintenance of human articular cartilage in culture for biomaterial testing.
Biomaterials 2005;26(22):4540-9.
2005: Karl Schumacher; Jürgen Klar; Charlotte Wagner; Will W Minuth
Temporal-spatial co-localisation of tissue transglutaminase (Tgase2) and matrix metalloproteinase-9 (MMP-9) with SBA-positive micro-fibres in the embryonic kidney cortex.
Cell and tissue research 2005;319(3):491-500.
2005: Will W Minuth; Karl Schumacher; Raimund Strehl
Renal epithelia in long term gradient culture for biomaterial testing and tissue engineering.
Bio-medical materials and engineering 2005;15(1-2):51-63.
2004: Raimund Strehl; Karl Schumacher; Will W Minuth
Controlled respiratory gas delivery to embryonic renal epithelial explants in perfusion culture.
Tissue engineering 2004;10(7-8):1196-203.
2004: Will W Minuth; Lydia Sorokin; Karl Schumacher
Generation of renal tubules at the interface of an artificial interstitium.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2004;14(4-6):387-94.
2004: Will W Minuth; Raimund Strehl; Karl Schumacher
Tissue factory: conceptual design of a modular system for the in vitro generation of functional tissues.
Tissue engineering 2004;10(1-2):285-94.
2003: Will W Minuth; Karl Schumacher
[From the renal stem cell niche to functional tubule].
Medizinische Klinik (Munich, Germany : 1983) 2003;98 Suppl 2():31-5.
2003: Karl Schumacher; Raimund Strehl; Will W Minuth
Urea restrains aldosterone-induced development of peanut agglutinin-binding on embryonic renal collecting duct epithelia.
Journal of the American Society of Nephrology : JASN 2003;14(11):2758-66.
2003: Karl Schumacher; Raimund Strehl; Will W Minuth
Characterization of micro-fibers at the interface between the renal collecting duct ampulla and the cap condensate.
Nephron. Experimental nephrology 2003;95(2):e43-54.
2002: Karl Schumacher; Raimund Strehl; Uwe de Vries; Hermann Josef Groene; Will W Minuth
SBA-positive fibers between the CD ampulla, mesenchyme, and renal capsule.
Journal of the American Society of Nephrology : JASN 2002;13(10):2446-53.
2002: Karl Schumacher; Raimund Strehl; Will W Minuth
Detection of glycosylated sites in embryonic rabbit kidney by lectin chemistry.
Histochemistry and cell biology 2002;118(1):79-87.
2002: Raimund Strehl; Karl Schumacher; Uwe de Vries; Will W Minuth
Proliferating cells versus differentiated cells in tissue engineering.
Tissue engineering 2002;8(1):37-42.
2002: Karl Schumacher; Raimund Strehl; Vries Uwe de; Will W Minuth
Advanced technique for long term culture of epithelia in a continuous luminal-basal medium gradient.
Biomaterials 2002;23(3):805-15.
2002: Karl Schumacher; Hayo Castrop; Raimund Strehl; Uwe de Vries; Will W Minuth
Cyclooxygenases in the collecting duct of neonatal rabbit kidney.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2002;12(2-3):63-74.
2001: Raimund Strehl; Will W Minuth
Partial identification of the mab (CD)Amp1 antigen at the epithelial-mesenchymal interface in the developing kidney.
Histochemistry and cell biology 2001;116(5):389-96.
2001: Karl Schumacher; S Klotz-Vangerow; M Tauc; Will W Minuth
Embryonic renal collecting duct cell differentiation is influenced in a concentration-dependent manner by the electrolyte environment.
American journal of nephrology 2001;21(2):165-75.
2001: Will W Minuth; Raimund Strehl; Karl Schumacher; Uwe de Vries
Long term culture of epithelia in a continuous fluid gradient for biomaterial testing and tissue engineering.
Journal of biomaterials science. Polymer edition 2001;12(3):353-65.
2001: Raimund Strehl; Will W Minuth
Nephron induction--the epithelial mesenchymal interface revisited.
Pediatric nephrology (Berlin, Germany) 2001;16(1):38-40.
2000: Will W Minuth; Karl Schumacher; Raimund Strehl; S Kloth
Physiological and cell biological aspects of perfusion culture technique employed to generate differentiated tissues for long term biomaterial testing and tissue engineering.
Journal of biomaterials science. Polymer edition 2000;11(5):495-522.
1999: Raimund Strehl; V Trautner; S Kloth; Will W Minuth
Existence of a dense reticular meshwork surrounding the nephron inducer in neonatal rabbit kidney.
Cell and tissue research 1999;298(3):539-48.
1999: Will W Minuth; P Steiner; Raimund Strehl; Karl Schumacher; Uwe de Vries; S Kloth
Modulation of cell differentiation in perfusion culture.
Experimental nephrology 1999;7(5-6):394-406.
1999: Karl Schumacher; Raimund Strehl; S Kloth; M Tauc; Will W Minuth
The influence of culture media on embryonic renal collecting duct cell differentiation.
In vitro cellular & developmental biology. Animal 1999;35(8):465-71.
1998: S Kloth; Elfriede Eckert; S J Klein; Jan Monzer; C Wanke; Will W Minuth
Gastric epithelium under organotypic perfusion culture.
In vitro cellular & developmental biology. Animal 1998;34(7):515-7.
1998: S Kloth; T Gmeiner; Joachim Aigner; M L Jennings; W Röckl; Will W Minuth
Transitional stages in the development of the rabbit renal collecting duct.
Differentiation; research in biological diversity 1998;63(1):21-32.
1998: S Kloth; J Gerdes; C Wanke; Will W Minuth
Basic fibroblast growth factor is a morphogenic modulator in kidney vessel development.
Kidney international 1998;53(4):970-8.
1998: Will W Minuth; Michael Sittinger; S Kloth
Tissue engineering: generation of differentiated artificial tissues for biomedical applications.
Cell and tissue research 1998;291(1):1-11.
1997: P Steiner; Raimund Strehl; S Kloth; M Tauc; Will W Minuth
In vitro development and preservation of specific features of collecting duct epithelial cells from embryonic rabbit kidney are regulated by the electrolyte environment.
Differentiation; research in biological diversity 1997;62(4):193-202.
1997: Raimund Strehl; S Kloth; Joachim Aigner; P Steiner; Will W Minuth
PCDAmp1, a new antigen at the interface of the embryonic collecting duct epithelium and the nephrogenic mesenchyme.
Kidney international 1997;52(6):1469-77.
1997: Will W Minuth; P Steiner; Raimund Strehl; S Kloth; M Tauc
Electrolyte environment modulates differentiation in embryonic renal collecting duct epithelia.
Experimental nephrology 1997;5(5):414-22.
1997: Will W Minuth; Joachim Aigner; S Kloth; P Steiner; M Tauc; M L Jennings
Culture of embryonic renal collecting duct epithelia in a gradient container.
Pediatric nephrology (Berlin, Germany) 1997;11(2):140-7.
1997: P Lehmann; S Kloth; Joachim Aigner; R Dammer; Will W Minuth
[Vital long-term preservation of human gingiva in perfusion culture].
Mund-, Kiefer- und Gesichtschirurgie : MKG 1997;1(1):26-30.
1997: Michael Sittinger; Olaf Schultz; Gernot Keyszer; Will W Minuth; Gerd R Burmester
Artificial tissues in perfusion culture.
The International journal of artificial organs 1997;20(1):57-62.
1997: Will W Minuth; Joachim Aigner; B Kubat; S Kloth
Improved differentiation of renal tubular epithelium in vitro: potential for tissue engineering.
Experimental nephrology 1997;5(1):10-7.
1997: S Kloth; C Ebenbeck; Jan Monzer; Uwe de Vries; Will W Minuth
Three-dimensional organization of the developing vasculature of the kidney.
Cell and tissue research 1997;287(1):193-201.
1996: Will W Minuth; S Kloth; Joachim Aigner; Michael Sittinger; W Röckl
Approach to an organo-typical environment for cultured cells and tissues.
BioTechniques 1996;20(3):498-501.
1995: J Bujía; Nicole Rotter; Will W Minuth; G Burmester; C Hammer; Michael Sittinger
[Cultivation of human cartilage tissue in a 3-dimensional perfusion culture chamber: characterization of collagen synthesis].
Laryngo- rhino- otologie 1995;74(9):559-63.
1995: S Kloth; Joachim Aigner; M Kubitza; A Schmidbauer; J Gerdes; R Moll; Will W Minuth
Development of renal podocytes cultured under medium perifusion.
Laboratory investigation; a journal of technical methods and pathology 1995;73(2):294-301.
1995: S Kloth; C Ebenbeck; M Kubitza; A Schmidbauer; W Röckl; Will W Minuth
Stimulation of renal microvascular development under organotypic culture conditions.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(10):963-7.
1995: J Bujia; Michael Sittinger; Will W Minuth; C Hammer; G Burmester; Ernst Kastenbauer
Engineering of cartilage tissue using bioresorbable polymer fleeces and perfusion culture.
Acta oto-laryngologica 1995;115(2):307-10.
1995: Joachim Aigner; S Kloth; M L Jennings; Will W Minuth
Transitional differentiation patterns of principal and intercalated cells during renal collecting duct development.
Epithelial cell biology 1995;4(3):121-30.
1994: S Kloth; Joachim Aigner; A Schmidbauer; Will W Minuth
Interrelationship of renal vascular development and nephrogenesis.
Cell and tissue research 1994;277(2):247-57.
1994: S Kloth; A Schmidbauer; M Kubitza; H A Weich; Will W Minuth
Developing renal microvasculature can be maintained under perfusion culture conditions.
European journal of cell biology 1994;63(1):84-95.
1994: Will W Minuth; S Kloth; V Majer; R Dermietzel
Growth of MDCK cells on non-transparent supports.
In vitro cellular & developmental biology. Animal 1994;30A(1):12-4.
1994: Joachim Aigner; S Kloth; M Kubitza; M Kashgarian; R Dermietzel; Will W Minuth
Maturation of renal collecting duct cells in vivo and under perifusion culture.
Epithelial cell biology 1994;3(2):70-8.
1993: Will W Minuth; W Fietzek; S Kloth; Joachim Aigner; Peter Herter; W Röckl; M Kubitza; G Stöckl; R Dermietzel
Aldosterone modulates PNA binding cell isoforms within renal collecting duct epithelium.
Kidney international 1993;44(3):537-44.
1993: S Kloth; Joachim Aigner; E Brandt; R Moll; Will W Minuth
Histochemical markers reveal an unexpected heterogeneous composition of the renal embryonic collecting duct epithelium.
Kidney international 1993;44(3):527-36.
1993: Peter Herter; G Laube; J Gronczewski; Will W Minuth
Silver-enhanced colloidal-gold labelling of rabbit kidney collecting-duct cell surfaces imaged by scanning electron microscopy.
Journal of microscopy 1993;171(Pt 2):107-15.
1992: S Kloth; D Meyer; W Röckl; A Miettinen; Joachim Aigner; A Schmidbauer; Will W Minuth
Characterization of an endothelial protein in the developing rabbit kidney.
Differentiation; research in biological diversity 1992;52(1):79-88.
1992: Will W Minuth; G Stöckl; S Kloth; R Dermietzel
Construction of an apparatus for perfusion cell cultures which enables in vitro experiments under organotypic conditions.
European journal of cell biology 1992;57(1):132-7.
1992: Will W Minuth; R Dermietzel; S Kloth; B Hennerkes
A new method culturing renal cells under permanent superfusion and producing a luminal-basal medium gradient.
Kidney international 1992;41(1):215-9.
1990: P Gilbert; Peter Mundel; Will W Minuth
Production of monoclonal antibodies against principal cells of the renal collecting duct by in vitro immunization with unsolubilized antigens.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1990;38(12):1919-25.
1990: M Zwanzig; Will W Minuth; P Gross
Action of aldosterone on cultured renal collecting duct cells during the latent period.
Renal physiology and biochemistry 1990;13(6):285-94.
1990: Will W Minuth; U Rudolph
Successive lectin-binding changes within the collecting duct during post-natal development of the rabbit kidney.
Pediatric nephrology (Berlin, Germany) 1990;4(5):505-9.
1990: Will W Minuth; U Rudolph
A compatible support system for cell culture in biomedical research.
Cytotechnology 1990;4(2):181-9.
1989: Will W Minuth; M Zwanzig; P Gross
Action of aldosterone on protein expression in cultured collecting duct cells from neonatal rabbit kidney.
Renal physiology and biochemistry 1989;12(4):213-27.
1989: Will W Minuth; M Struck; M Zwanzig; P Gross
Action of aldosterone on citrate synthase in cultured renal collecting duct cells.
Renal physiology and biochemistry 1989;12(2):85-95.
1989: Will W Minuth; P Gilbert; U Rudolph; W S Spielman
Successive histochemical differentiation steps during postnatal development of the collecting duct in rabbit kidney.
Histochemistry 1989;93(1):19-25.
1988: Will W Minuth; P Gilbert; P Gross
Appearance of specific proteins in the apical plasma membrane of cultured renal collecting duct principal cell epithelium after chronic administration of aldosterone and arginine vasopressin.
Differentiation; research in biological diversity 1988;38(3):194-202.
1988: G Lauer; Will W Minuth
Apico-basal osmotic gradient induces transcytosis in cultured renal collecting duct epithelium.
The Journal of membrane biology 1988;101(2):93-101.
1988: Will W Minuth; P Gilbert
The expression of specific proteins in cultured renal collecting duct cells.
Histochemistry 1988;88(3-6):435-41.
1988: Will W Minuth; Ulrike Muscha Steckelings; P Gross
Complex physiological and biochemical action of aldosterone in toad urinary bladder and mammalian renal collecting duct cells.
Renal physiology 1988;10(6):297-310.
1987: Sebastian Bachmann; P Gilbert; Will W Minuth
Electron-microscopic immunogold localization of a collecting-duct antigen (PCD2) in intercalated and principal cells of rabbit kidney.
Cell and tissue research 1987;249(3):633-40.
1987: Will W Minuth; Ulrike Muscha Steckelings; P Gross
Methylation of cytosolic proteins may be a possible biochemical pathway of early aldosterone action in cultured renal collecting duct cells.
Differentiation; research in biological diversity 1987;36(1):23-34.
1987: Will W Minuth
Neonatal rabbit kidney cortex in culture as tool for the study of collecting duct formation and nephron differentiation.
Differentiation; research in biological diversity 1987;36(1):12-22.
1986: Will W Minuth; P Gilbert; G Lauer; K Aktories; P Gross
Differentiation properties of renal collecting duct cells in culture.
Differentiation; research in biological diversity 1986;33(2):156-67.
1984: Will W Minuth; G Lauer; S Bachmann; W Kriz
Immunocytochemical localization of a renal glycoprotein (gpCDI) synthesized by cultured collecting duct cells.
Histochemistry 1984;80(2):171-82.