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Pierre Miossec

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All Publications

2013: Pierre Miossec
Kinase inhibition in rheumatoid arthritis: a big advance?
Lancet 2013;381(9865):429-31.
2013: Anne Tournadre; Pierre Miossec
Immunoregulation in idiopathic inflammatory myopathies: from dendritic cells to immature regenerating muscle cells.
The Journal of rheumatology 2013;40(2):110-2.
2012: Pierre Miossec; Jay K Kolls
Targeting IL-17 and TH17 cells in chronic inflammation.
Nature reviews. Drug discovery 2012;11(10):763-76.
2012: Arnaud Hot; Vanina Lenief; Saloua Zrioual; Pierre Miossec
IL-17 and tumour necrosis factor α combination induces a HIF-1α-dependent invasive phenotype in synoviocytes.
Annals of the rheumatic diseases 2012;71(8):1393-401.
2012: Gwendoline Toulemonde; Jean-Yves Scoazec; Pierre Miossec
Treatment with etanercept of autoimmune hepatitis associated with rheumatoid arthritis: an open label proof of concept study.
Annals of the rheumatic diseases 2012;71(8):1423-4.
2012: Anne Tournadre; Pierre Miossec
Interleukin-17 in inflammatory myopathies.
Current rheumatology reports 2012;14(3):252-6.
2012: Anne Tournadre; Assia Eljaafari; Vanina Lenief; Pierre Miossec
Immature muscle precursors are a source of interferon-β in myositis: role of Toll-like receptor 3 activation and contribution to HLA class I up-regulation.
Arthritis and rheumatism 2012;64(2):533-41.
2011: Pierre Miossec; B Mitlak; S Mpofu; Sif Ormarsdóttir; C Pitzalis; R Rao; Jean-Yves Reginster; S Reiter; Yannis Tsouderos; C L Verweij; Eric Abadie; A Barton; Ferdinand C Breedveld; W Dere; Dominique Ethgen; Bruno Flamion; N Goel; L Klareskog; Andrea Laslop; Fritz Lekkerkerker
Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies.
Annals of the rheumatic diseases 2011;70(10):1713-8.
2011: Josef S Smolen; Eric C Abadie; Bernard P Avouac; Thomas Bardin; Maarten Boers; Ferdinand C Breedveld; Patrick Durez; Paul Emery; Dominique J Ethgen; Bruno Flamion; Niti Goel; Andrea Laslop; Pierre Miossec; Jean-Yves Reginster; Susanne Reiter
Updating the 2003 European regulatory requirements for registering disease-modifying drugs to be used in the treatment of rheumatoid arthritis.
Rheumatology (Oxford, England) 2011;50(10):1732-6.
2011: Arnaud Hot; Pierre Miossec
Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes.
Annals of the rheumatic diseases 2011;70(5):727-32.
2011: Josef S Smolen; Maarten Boers; Eric C Abadie; Ferdinand C Breedveld; Paul Emery; Thomas Bardin; Niti Goel; Dominique J Ethgen; Bernard P Avouac; Willard H Dere; Patrick Durez; Marco Matucci-Cerinic; Bruno Flamion; Andrea Laslop; Frits J Lekkerkerker; Pierre Miossec; Bruce H Mitlak; Sif Ormarsdóttir; Laurence Paolozzi; Ravi Rao; Susan Reiter; Yannis Tsouderos; Jean-Yves Reginster
Recommendations for an update of 2003 European regulatory requirements for registration of drugs to be used in the treatment of RA.
Current medical research and opinion 2011;27(2):315-25.
2011: Arnaud Hot; Saloua Zrioual; Myew-Ling Toh; Vanina Lenief; Pierre Miossec
IL-17A- versus IL-17F-induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in rheumatoid synoviocytes.
Annals of the rheumatic diseases 2011;70(2):341-8.
2011: Frédéric Reynier; Fanny Turrel-Davin; Arnaud Hot; Pierre-Emmanuel Imbert; Bruno Mougin; Malick Paye; Fabien Petit; Pierre Miossec
Importance of correlation between gene expression levels: application to the type I interferon signature in rheumatoid arthritis.
PloS one 2011;6(10):e24828.
2010: Anne Fouque-Aubert; Stéphanie Boutroy; Hubert Marotte; Nicolas Vilayphiou; Justine Bacchetta; Pierre Miossec; Pierre Dominique Delmas; Roland D Chapurlat
Assessment of hand bone loss in rheumatoid arthritis by high-resolution peripheral quantitative CT.
Annals of the rheumatic diseases 2010;69(9):1671-6.
2010: Myew-Ling Toh; Masanori Kawashima; Arnaud Hot; Pierre Miossec; Pierre Miossec
Role of IL-17 in the Th1 systemic defects in rheumatoid arthritis through selective IL-12Rbeta2 inhibition.
Annals of the rheumatic diseases 2010;69(8):1562-7.
2010: Hubert Marotte; Pierre Miossec
Biomarkers for prediction of TNFalpha blockers response in rheumatoid arthritis.
Joint, bone, spine : revue du rhumatisme 2010;77(4):297-305.
2010: Anne Fouque-Aubert; Roland D Chapurlat; Pierre Miossec; Pierre D Delmas
A comparative review of the different techniques to assess hand bone damage in rheumatoid arthritis.
Joint, bone, spine : revue du rhumatisme 2010;77(3):212-7.
2010: Fanny Turrel-Davin; Anne Tournadre; Alexandre Pachot; Béatrice Arnaud; Marie-Angélique Cazalis; Bruno Mougin; Pierre Miossec
FoxO3a involved in neutrophil and T cell survival is overexpressed in rheumatoid blood and synovial tissue.
Annals of the rheumatic diseases 2010;69(4):755-60.
2010: Myew-Ling Toh; Gaelle Gonzales; Marije I Koenders; Anne Tournadre; David Boyle; Erik Lubberts; Yuan Zhou; Gary S Firestein; Wim B van den Berg; Pierre Miossec
Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression.
PloS one 2010;5(10):e13416.
2010: Emilie Quintin; Jean-Yves Scoazec; Hubert Marotte; Pierre Miossec
Rare incidence of methotrexate-specific lesions in liver biopsy of patients with arthritis and elevated liver enzymes.
Arthritis research & therapy 2010;12(4):R143.
2010: Hubert Marotte; Evelyne Gineyts; Pierre Miossec
Prolidase deficiency: a rare aetiology of arthritis.
Joint, bone, spine : revue du rhumatisme 2010;77(1):88-9.
2009: Myew-Ling Toh; Masanori Kawashima; Saloua Zrioual; Arnaud Hot; Pierre Miossec; Pierre Miossec
IL-17 inhibits human Th1 differentiation through IL-12R beta 2 downregulation.
Cytokine 2009;48(3):226-30.
2009: Wim B van den Berg; Pierre Miossec
IL-17 as a future therapeutic target for rheumatoid arthritis.
Nature reviews. Rheumatology 2009;5(10):549-53.
2009: Assia Eljaafari; Yin-Ping Li; Pierre Miossec
IFN-gamma, as secreted during an alloresponse, induces differentiation of monocytes into tolerogenic dendritic cells, resulting in FoxP3+ regulatory T cell promotion.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(5):2932-45.
2009: Pierre Miossec; Thomas Korn; Vijay K Kuchroo
Interleukin-17 and type 17 helper T cells.
The New England journal of medicine 2009;361(9):888-98.
2009: Hubert Marotte; E Gineyts; Pierre Miossec; P D Delmas
Effects of infliximab therapy on biological markers of synovium activity and cartilage breakdown in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2009;68(7):1197-200.
2009: Ophélia Granio; Marine Porcherot; Stephanie Corjon; Kuntida Kitidee; Petra Henning; Assia Eljaafari; Andrea Cimarelli; Leif Lindholm; Pierre Miossec; Pierre Boulanger; Saw See Hong
Improved adenovirus type 5 vector-mediated transduction of resistant cells by piggybacking on coxsackie B-adenovirus receptor-pseudotyped baculovirus.
Journal of virology 2009;83(12):6048-66.
2009: Anne Tournadre; Marine Porcherot; Patrick Chérin; Isabelle Marie; Eric Hachulla; Pierre Miossec
Th1 and Th17 balance in inflammatory myopathies: interaction with dendritic cells and possible link with response to high-dose immunoglobulins.
Cytokine 2009;46(3):297-301.
2009: Pierre Miossec
IL-17 and Th17 cells in human inflammatory diseases.
Microbes and infection / Institut Pasteur 2009;11(5):625-30.
2009: Pierre Miossec
Diseases that may benefit from manipulating the Th17 pathway.
European journal of immunology 2009;39(3):667-9.
2009: Saloua Zrioual; René Ecochard; Anne Tournadre; Vanina Lenief; Marie-Angélique Cazalis; Pierre Miossec
Genome-wide comparison between IL-17A- and IL-17F-induced effects in human rheumatoid arthritis synoviocytes.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):3112-20.
2009: R Mathieux; Hubert Marotte; L Battistini; A Sarrazin; M Berthier; Pierre Miossec
Early occupational therapy programme increases hand grip strength at 3 months: results from a randomised, blind, controlled study in early rheumatoid arthritis.
Annals of the rheumatic diseases 2009;68(3):400-3.
2009: Carlo Chizzolini; Jean-Michel Dayer; Pierre Miossec
Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance?
Arthritis research & therapy 2009;11(5):246.
2008: Hubert Marotte; Pierre Miossec
Prevention of bone mineral density loss in patients with rheumatoid arthritis treated with anti-TNFalpha therapy.
Biologics : targets & therapy 2008;2(4):663-9.
2008: Samar Kerkeni; Hubert Marotte; Pierre Miossec
Improvement with rituximab in a patient with both rheumatoid arthritis and myasthenia gravis.
Muscle & nerve 2008;38(4):1343-5.
2008: Hubert Marotte; Béatrice Arnaud; Jennifer Diasparra; Saloua Zrioual; Pierre Miossec
Association between the level of circulating bioactive tumor necrosis factor alpha and the tumor necrosis factor alpha gene polymorphism at -308 in patients with rheumatoid arthritis treated with a tumor necrosis factor alpha inhibitor.
Arthritis and rheumatism 2008;58(5):1258-63.
2008: Marie-George Lapalus; Arnaud Hot; Aurélie Fontana; Olivier Guillaud; Pierre Miossec; Jean-Yves Scoazec; Jérôme Dumortier
Epstein Barr virus-induced hepatitis associated with methotrexate treatment.
Journal of clinical gastroenterology 2008;42(2):217-9.
2008: Yin-Ping Li; Sophie Paczesny; Evelyne Lauret; Sonia Poirault; Pierre Bordigoni; Fatiha Mekhloufi; Olivier Hequet; Yves Bertrand; Jing-Ping Ou-Yang; Jean-François Stoltz; Pierre Miossec; Assia Eljaafari
Human mesenchymal stem cells license adult CD34+ hemopoietic progenitor cells to differentiate into regulatory dendritic cells through activation of the Notch pathway.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(3):1598-608.
2008: Pierre Miossec
Dynamic interactions between T cells and dendritic cells and their derived cytokines/chemokines in the rheumatoid synovium.
Arthritis research & therapy 2008;10 Suppl 1():S2.
2008: Saloua Zrioual; Myew-Ling Toh; Yuan Zhou; Yuan Zhou; Marie-Angélique Cazalis; Alexandre Pachot; Vincent Miossec; Pierre Miossec
IL-17RA and IL-17RC receptors are essential for IL-17A-induced ELR+ CXC chemokine expression in synoviocytes and are overexpressed in rheumatoid blood.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(1):655-63.
2007: Alexandre Pachot; Véronique Barbalat; Hubert Marotte; Jennifer Diasparra; Aurore Gouraud; Bruno Mougin; Pierre Miossec
A rapid semi automated method for DNA extraction from dried-blood spots: application to the HLA-DR shared epitope analysis in rheumatoid arthritis.
Journal of immunological methods 2007;328(1-2):220-5.
2007: Alexandre Pachot; Béatrice Arnaud; Hubert Marrote; Marie-Angélique Cazalis; Jennifer Diasparra; Aurore Gouraud; Bruno Mougin; Pierre Miossec
Increased tumor necrosis factor-alpha mRNA expression in whole blood from patients with rheumatoid arthritis: reduction after infliximab treatment does not predict response.
The Journal of rheumatology 2007;34(11):2158-61.
2007: Anne Tournadre; Pierre Miossec
Cytokine response in inflammatory myopathies.
Current rheumatology reports 2007;9(4):286-90.
2007: Pierre Miossec
Interleukin-17 in fashion, at last: ten years after its description, its cellular source has been identified.
Arthritis and rheumatism 2007;56(7):2111-5.
2007: Rolando Cimaz; Marie-Angélique Cazalis; Charlotte Reynaud; Valeria Gerloni; Francesco Zulian; Martina Biggioggero; Giorgia Martini; Irene Pontikaki; Flavio Fantini; Bruno Mougin; Pierre Miossec
IL1 and TNF gene polymorphisms in patients with juvenile idiopathic arthritis treated with TNF inhibitors.
Annals of the rheumatic diseases 2007;66(7):900-4.
2007: Yuan Zhou; Myew-Ling Toh; Yuan Zhou; Pierre Miossec
IL-17A versus IL-17F induced intracellular signal transduction pathways and modulation by IL-17RA and IL-17RC RNA interference in AGS gastric adenocarcinoma cells.
Cytokine 2007;38(3):157-64.
2007: Myew-Ling Toh; Pierre Miossec
The role of T cells in rheumatoid arthritis: new subsets and new targets.
Current opinion in rheumatology 2007;19(3):284-8.
2007: Benoit Morel; Hubert Marotte; Pierre Miossec
Will steroidal aromatase inhibitors induce rheumatoid arthritis?
Annals of the rheumatic diseases 2007;66(4):557-8.
2007: Leyla Kazkaz; Hubert Marotte; Mayassa Hamwi; Marie Angélique Cazalis; Pascal Roy; Bruno Mougin; Pierre Miossec
Rheumatoid arthritis and genetic markers in Syrian and French populations: different effect of the shared epitope.
Annals of the rheumatic diseases 2007;66(2):195-201.
2007: Hubert Marotte; Beatrice Pallot-Prades; Laurent Grange; philippe gaudin; Christian Alexandre; Pierre Miossec
A 1-year case-control study in patients with rheumatoid arthritis indicates prevention of loss of bone mineral density in both responders and nonresponders to infliximab.
Arthritis research & therapy 2007;9(3):R61.
2007: Hubert Marotte; Elisabeth Fontanges; F Bailly; F Zoulim; C Trepo; Pierre Miossec
Etanercept treatment for three months is safe in patients with rheumatological manifestations associated with hepatitis C virus.
Rheumatology (Oxford, England) 2007;46(1):97-9.
2006: Assia Eljaafari; Lionel Badet; Jean Kanitakis; Christophe Ferrand; Annie Farre; Palmina Petruzzo; Emmanuel Morelon; Muriel Dubosson; Pierre Tiberghien; Valérie Dubois; Xavier Martin; Pierre Miossec; Jean-Michel Dubernard
Isolation of regulatory T cells in the skin of a human hand-allograft, up to six years posttransplantation.
Transplantation 2006;82(12):1764-8.
2006: Marie Miossec; Pierre Miossec
New regulatory rules for clinical trials in the United States and the European Union: key points and comparisons.
Arthritis and rheumatism 2006;54(12):3735-40.
2006: Hubert Marotte; M Tournoud; Marie-Angélique Cazalis; Bruno Mougin; P Roy; Pierre Miossec
Extensive multiallelic analysis of the relationship between HLA-DRB1 and rheumatoid arthritis using a Bayesian partition model.
Genes and immunity 2006;7(6):487-93.
2006: Myew-Ling Toh; Hubert Marotte; Jean-Luc Blond; Umar Jhumka; Assia Eljaafari; Bruno Mougin; Pierre Miossec
Overexpression of synoviolin in peripheral blood and synoviocytes from rheumatoid arthritis patients and continued elevation in nonresponders to infliximab treatment.
Arthritis and rheumatism 2006;54(7):2109-18.
2006: Hubert Marotte; Pierre Farge; philippe gaudin; Christian Alexandre; Bruno Mougin; Pierre Miossec
The association between periodontal disease and joint destruction in rheumatoid arthritis extends the link between the HLA-DR shared epitope and severity of bone destruction.
Annals of the rheumatic diseases 2006;65(7):905-9.
2006: Guillaume Chevrel; Guillaume Page; Pierre Miossec
Novel aspects on the contribution of T cells and dendritic cells in the pathogenesis of myositis.
Autoimmunity 2006;39(3):171-6.
2006: Frederic Reynier; Marie-Angélique Cazalis; Annick Lecoq; Malick Paye; Audrey Rosa; Annie Durand; Umar Jhumka; Bruno Mougin; Pierre Miossec; Nathalie Bendelac; Marc Nicolino; Charles Thivolet
Lack of association of IL-10 promoter gene variants with type 1 diabetes in a French population.
Human immunology 2006;67(4-5):311-7.
2006: Hubert Marotte; Beatrice Pallot-Prades; Laurent Grange; Jacques Tebib; philippe gaudin; Christian Alexandre; Jean-Luc Blond; Marie-Angélique Cazalis; Bruno Mougin; Pierre Miossec
The shared epitope is a marker of severity associated with selection for, but not with response to, infliximab in a large rheumatoid arthritis population.
Annals of the rheumatic diseases 2006;65(3):342-7.
2005: Myew-Ling Toh; Saw See Hong; Fons A J van de Loo; Laure Franqueville; Leif Lindholm; Wim B van den Berg; Pierre Boulanger; Pierre Miossec
Enhancement of adenovirus-mediated gene delivery to rheumatoid arthritis synoviocytes and synovium by fiber modifications: role of arginine-glycine-aspartic acid (RGD)- and non-RGD-binding integrins.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(11):7687-98.
2005: Guillaume Chevrel; Corinne Granet; Pierre Miossec
Contribution of tumour necrosis factor alpha and interleukin (IL) 1beta to IL6 production, NF-kappaB nuclear translocation, and class I MHC expression in muscle cells: in vitro regulation with specific cytokine inhibitors.
Annals of the rheumatic diseases 2005;64(9):1257-62.
2005: Guillaume Page; Pierre Miossec
RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes.
Arthritis and rheumatism 2005;52(8):2307-12.
2005: M J Nissen; Elisabeth Fontanges; Y Allam; F Zoulim; C Trépo; Pierre Miossec
Rheumatological manifestations of hepatitis C: incidence in a rheumatology and non-rheumatology setting and the effect of methotrexate and interferon.
Rheumatology (Oxford, England) 2005;44(8):1016-20.
2005: Masanori Kawashima; Pierre Miossec
mRNA quantification of T-bet, GATA-3, IFN-gamma, and IL-4 shows a defective Th1 immune response in the peripheral blood from rheumatoid arthritis patients: link with disease activity.
Journal of clinical immunology 2005;25(3):209-14.
2005: Alexis Benjamin Cortot; Vincent Cottin; Pierre Miossec; Eric Fauchon; Françoise Thivolet-Béjui; Jean-François Cordier
Improvement of refractory rheumatoid arthritis-associated constrictive bronchiolitis with etanercept.
Respiratory medicine 2005;99(4):511-4.
2005: M Kawashima; Pierre Miossec
Effect of treatment of rheumatoid arthritis with infliximab on IFN gamma, IL4, T-bet, and GATA-3 expression: link with improvement of systemic inflammation and disease activity.
Annals of the rheumatic diseases 2005;64(3):415-8.
2005: Hubert Marotte; Wlodzimierz Maslinski; Pierre Miossec
Circulating tumour necrosis factor-alpha bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response.
Arthritis research & therapy 2005;7(1):R149-55.
2005: D Gensburger; M Kawashima; Hubert Marotte; Jean Kanitakis; Pierre Miossec
Lupus erythematosus with leflunomide: induction or reactivation?
Annals of the rheumatic diseases 2005;64(1):153-5.
2004: Pierre Miossec
[Autoimmune pathologies. Epidemiological and diagnostic aspects, principles of treatment].
La Revue du praticien 2004;54(19):2187-93.
2004: Alexandre Pachot; Jean-Luc Blond; Bruno Mougin; Pierre Miossec
Peptidylpropyl isomerase B (PPIB): a suitable reference gene for mRNA quantification in peripheral whole blood.
Journal of biotechnology 2004;114(1-2):121-4.
2004: J Wegrzyn; P Adeleine; Pierre Miossec
Better efficacy of methotrexate given by intramuscular injection than orally in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2004;63(10):1232-4.
2004: Guillaume Page; Pierre Miossec
Paired synovium and lymph nodes from rheumatoid arthritis patients differ in dendritic cell and chemokine expression.
The Journal of pathology 2004;204(1):28-38.
2004: Masanori Kawashima; Daniela Novick; Menachem Rubinstein; Pierre Miossec
Regulation of interleukin-18 binding protein production by blood and synovial cells from patients with rheumatoid arthritis.
Arthritis and rheumatism 2004;50(6):1800-5.
2004: Corinne Granet; Pierre Miossec
Combination of the pro-inflammatory cytokines IL-1, TNF-alpha and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-kappaB in osteoblast-like cells.
Cytokine 2004;26(4):169-77.
2004: Pierre Miossec
An update on the cytokine network in rheumatoid arthritis.
Current opinion in rheumatology 2004;16(3):218-22.
2004: Pierre Miossec
IL-17 in rheumatoid arthritis: a new target for treatment or just another cytokine?
Joint, bone, spine : revue du rhumatisme 2004;71(2):87-90.
2004: Guillaume Page; Arne Sattler; Sabine Kersten; Andreas Thiel; Andreas Radbruch; Pierre Miossec
Plasma cell-like morphology of Th1-cytokine-producing cells associated with the loss of CD3 expression.
The American journal of pathology 2004;164(2):409-17.
2004: Corinne Granet; Wova Maslinski; Pierre Miossec
Increased AP-1 and NF-kappaB activation and recruitment with the combination of the proinflammatory cytokines IL-1beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes.
Arthritis research & therapy 2004;6(3):R190-8.
2004: Guillaume Page; Guillaume Chevrel; Pierre Miossec
Anatomic localization of immature and mature dendritic cell subsets in dermatomyositis and polymyositis: Interaction with chemokines and Th1 cytokine-producing cells.
Arthritis and rheumatism 2004;50(1):199-208.
2003: Guillaume Chevrel; Guillaume Page; Corinne Granet; N Streichenberger; A Varennes; Pierre Miossec
Interleukin-17 increases the effects of IL-1 beta on muscle cells: arguments for the role of T cells in the pathogenesis of myositis.
Journal of neuroimmunology 2003;137(1-2):125-33.
2003: Pierre Miossec
[Physiopathology of inflammation].
La Revue du praticien 2003;53(5):482-8.
2003: Masanori Kawashima; Pierre Miossec
Heterogeneity of response of rheumatoid synovium cell subsets to interleukin-18 in relation to differential interleukin-18 receptor expression.
Arthritis and rheumatism 2003;48(3):631-7.
2003: Pierre Miossec
Interleukin-17 in rheumatoid arthritis: if T cells were to contribute to inflammation and destruction through synergy.
Arthritis and rheumatism 2003;48(3):594-601.
2003: Guillaume Chevrel; J P Borsotti; Pierre Miossec
Lack of evidence for a direct involvement of muscle infection by parvovirus B19 in the pathogenesis of inflammatory myopathies: a follow-up study.
Rheumatology (Oxford, England) 2003;42(2):349-52.
2002: Julien Wegrzyn; Jean-Michel Livrozet; Jean-Louis Touraine; Pierre Miossec
Rheumatoid arthritis after 9 years of human immunodeficiency virus infection: possible contribution of tritherapy.
The Journal of rheumatology 2002;29(10):2232-4.
2002: Pierre Miossec
Anti-interleukin 1alpha autoantibodies.
Annals of the rheumatic diseases 2002;61(7):577-9.
2002: Guillaume Page; Serge Lebecque; Pierre Miossec
Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(10):5333-41.
2002: Maurice Bouysset; Jacques Tebib; Eric Noel; Thierry Tavernier; Pierre Miossec; Jean-Claude Vianey; Jean-Pierre Duivon; Michel Bonnin; Chantal Nemoz; Jocelyne Jalby
Rheumatoid flat foot and deformity of the first ray.
The Journal of rheumatology 2002;29(5):903-5.
2001: M Chabaud; Guillaume Page; Pierre Miossec
Enhancing effect of IL-1, IL-17, and TNF-alpha on macrophage inflammatory protein-3alpha production in rheumatoid arthritis: regulation by soluble receptors and Th2 cytokines.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(10):6015-20.
2001: Bruno Mougin; P Garnero; O Borel; C Compagnon; Véronique Barbalat; Hubert Marotte; Pierre Miossec
A routine assay for the direct analysis of HLA-DR-related shared epitope and B27 alleles in chronic inflammatory arthritis.
Journal of immunological methods 2001;256(1-2):47-53.
2001: F Boyer; Elisabeth Fontanges; Pierre Miossec
Rheumatoid arthritis associated with ulcerative colitis: a case with severe flare of both diseases after delivery.
Annals of the rheumatic diseases 2001;60(9):901.
2001: G Chevrel; C Jenvrin; B McGregor; Pierre Miossec
Renal type AA amyloidosis associated with rheumatoid arthritis: a cohort study showing improved survival on treatment with pulse cyclophosphamide.
Rheumatology (Oxford, England) 2001;40(7):821-5.
2001: T Aarvak; E Strand; J Teigland; Pierre Miossec; Jacob B Natvig
Switch in chemokine receptor phenotype on memory T cells without a change in the cytokine phenotype.
Scandinavian journal of immunology 2001;54(1-2):100-8.
2001: Pierre Miossec
Cytokines in rheumatoid arthritis: is it all TNF-alpha?
Cellular and molecular biology (Noisy-le-Grand, France) 2001;47(4):675-8.
2001: N Buchs; Francesco S Di Giovine; Tania Silvestri; E Vannier; Gordon W Duff; Pierre Miossec
IL-1B and IL-1Ra gene polymorphisms and disease severity in rheumatoid arthritis: interaction with their plasma levels.
Genes and immunity 2001;2(4):222-8.
2001: M Chabaud; T Aarvak; P Garnero; Jacob B Natvig; Pierre Miossec
Potential contribution of IL-17-producing Th(1)cells to defective repair activity in joint inflammation: partial correction with Th(2)-promoting conditions.
Cytokine 2001;13(2):113-8.
2001: M Chabaud; Erik Lubberts; Leo A B Joosten; Wim B van den Berg; Pierre Miossec
IL-17 derived from juxta-articular bone and synovium contributes to joint degradation in rheumatoid arthritis.
Arthritis research 2001;3(3):168-77.
2000: N Buchs; Tania Silvestri; Francesco S Di Giovine; M Chabaud; E Vannier; Gordon W Duff; Pierre Miossec
IL-4 VNTR gene polymorphism in chronic polyarthritis. The rare allele is associated with protection against destruction.
Rheumatology (Oxford, England) 2000;39(10):1126-31.
2000: Guillaume Chevrel; A Calvet; V Belin; Pierre Miossec
Dermatomyositis associated with the presence of parvovirus B19 DNA in muscle.
Rheumatology (Oxford, England) 2000;39(9):1037-9.
2000: M Chabaud; P Garnero; J M Dayer; P A Guerne; F Fossiez; Pierre Miossec
Contribution of interleukin 17 to synovium matrix destruction in rheumatoid arthritis.
Cytokine 2000;12(7):1092-9.
2000: Erik Lubberts; Leo A B Joosten; M Chabaud; Liduine Van Den Bersselaar; Birgit Oppers; Christina J J Coenen-de Roo; Carl D Richards; Pierre Miossec; Wim B van den Berg
IL-4 gene therapy for collagen arthritis suppresses synovial IL-17 and osteoprotegerin ligand and prevents bone erosion.
The Journal of clinical investigation 2000;105(12):1697-710.
2000: T Aarvak; M Chabaud; Jørn E Thoen; Pierre Miossec; Jacob B Natvig
Changes in the Th1 or Th2 cytokine dominance in the synovium of rheumatoid arthritis (RA): a kinetic study of the Th subsets in one unusual RA patient.
Rheumatology (Oxford, England) 2000;39(5):513-22.
2000: Pierre Miossec
Are T cells in rheumatoid synovium aggressors or bystanders?
Current opinion in rheumatology 2000;12(3):181-5.
1999: T Aarvak; M Chabaud; Eva Källberg; Pierre Miossec; Jacob B Natvig
Change in the Th1/Th2 phenotype of memory T-cell clones from rheumatoid arthritis synovium.
Scandinavian journal of immunology 1999;50(1):1-9.
1999: M Chabaud; J M Durand; N Buchs; F Fossiez; Guillaume Page; Lucien Frappart; Pierre Miossec
Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium.
Arthritis and rheumatism 1999;42(5):963-70.
1999: Patrick Garnero; P Jouvenne; N Buchs; Pierre D Delmas; Pierre Miossec
Uncoupling of bone metabolism in rheumatoid arthritis patients with or without joint destruction: assessment with serum type I collagen breakdown products.
Bone 1999;24(4):381-5.
1999: P Jouvenne; A Chaudhary; N Buchs; F S Giovine; Gordon W Duff; Pierre Miossec
Possible genetic association between interleukin-1alpha gene polymorphism and the severity of chronic polyarthritis.
European cytokine network 1999;10(1):33-6.
1999: T Aarvak; M Chabaud; Pierre Miossec; Jacob B Natvig
IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1246-51.
1998: A Haddad; J Bienvenu; Pierre Miossec
Increased production of a Th2 cytokine profile by activated whole blood cells from rheumatoid arthritis patients.
Journal of clinical immunology 1998;18(6):399-403.
1998: R Paillot; Laurent Genestier; Sylvie Fournel; C Ferraro; Pierre Miossec; Jean-Pierre Revillard
Activation-dependent lymphocyte apoptosis induced by methotrexate.
Transplantation proceedings 1998;30(5):2348-50.
1998: Laurent Genestier; R Paillot; Sylvie Fournel; C Ferraro; Pierre Miossec; Jean-Pierre Revillard
Immunosuppressive properties of methotrexate: apoptosis and clonal deletion of activated peripheral T cells.
The Journal of clinical investigation 1998;102(2):322-8.
1998: M Chabaud; F Fossiez; J L Taupin; Pierre Miossec
Enhancing effect of IL-17 on IL-1-induced IL-6 and leukemia inhibitory factor production by rheumatoid arthritis synoviocytes and its regulation by Th2 cytokines.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):409-14.
1998: P Jouvenne; E Vannier; C A Dinarello; Pierre Miossec
Elevated levels of soluble interleukin-1 receptor type II and interleukin-1 receptor antagonist in patients with chronic arthritis: correlations with markers of inflammation and joint destruction.
Arthritis and rheumatism 1998;41(6):1083-9.
1997: Pierre Miossec; Wim B van den Berg
Th1/Th2 cytokine balance in arthritis.
Arthritis and rheumatism 1997;40(12):2105-15.
1997: Pierre Miossec
The role of the Th1 and Th2 dichotomy in the pathogenesis of juvenile chronic arthritis.
Revue du rhumatisme (English ed.) 1997;64(10 Suppl):138S-139S.
1997: P Jouvenne; F Fossiez; Jacques Banchereau; Pierre Miossec
High levels of neutralizing autoantibodies against IL-1 alpha are associated with a better prognosis in chronic polyarthritis: a follow-up study.
Scandinavian journal of immunology 1997;46(4):413-8.
1997: Pierre Miossec
Cytokines and the pathophysiology of bone erosions in rheumatoid arthritis.
Revue du rhumatisme (English ed.) 1997;64(6 Suppl):89S-91S.
1996: Marie-Clotilde Rissoan; C Van Kooten; P Chomarat; L Galibert; Isabelle Durand; F Thivolet-Bejui; Pierre Miossec; Jacques Banchereau
The functional CD40 antigen of fibroblasts may contribute to the proliferation of rheumatoid synovium.
Clinical and experimental immunology 1996;106(3):481-90.
1996: P Jouvenne; F Fossiez; Pierre Garrone; O Djossou; Jacques Banchereau; Pierre Miossec
Increased incidence of neutralizing autoantibodies against interleukin-1 alpha (IL-1 alpha) in nondestructive chronic polyarthritis.
Journal of clinical immunology 1996;16(5):283-90.
1996: Pierre Garrone; O Djossou; F Fossiez; J Reyes; Smina Ait-Yahia; C Maat; S Ho; T Hauser; J M Dayer; J Greffe; Pierre Miossec; Serge Lebecque; F Rousset; Jacques Banchereau
Generation and characterization of a human monoclonal autoantibody that acts as a high affinity interleukin-1 alpha specific inhibitor.
Molecular immunology 1996;33(7-8):649-58.
1996: Pierre Miossec; P Chomarat; J Dechanet
Bypassing the antigen to control rheumatoid arthritis.
Immunology today 1996;17(4):170-3.
1995: P Chomarat; Marie-Clotilde Rissoan; Jean-Jacques Pin; Jacques Banchereau; Pierre Miossec
Contribution of IL-1, CD14, and CD13 in the increased IL-6 production induced by in vitro monocyte-synoviocyte interactions.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(7):3645-52.
1995: P Chomarat; Jacques Banchereau; Pierre Miossec
Differential effects of interleukins 10 and 4 on the production of interleukin-6 by blood and synovium monocytes in rheumatoid arthritis.
Arthritis and rheumatism 1995;38(8):1046-54.
1995: Sandra Zurawski; P Chomarat; O Djossou; C Bidaud; Andrew N J McKenzie; Pierre Miossec; Jacques Banchereau; Gerard Zurawski
The primary binding subunit of the human interleukin-4 receptor is also a component of the interleukin-13 receptor.
The Journal of biological chemistry 1995;270(23):13869-78.
1995: P Chomarat; E Vannier; J Dechanet; Marie-Clotilde Rissoan; Jacques Banchereau; C A Dinarello; Pierre Miossec
Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(3):1432-9.
1995: J Dechanet; Marie-Clotilde Rissoan; Jacques Banchereau; Pierre Miossec
Interleukin 4, but not interleukin 10, regulates the production of inflammation mediators by rheumatoid synoviocytes.
Cytokine 1995;7(2):176-83.
1995: J Dechanet; Pierre Merville; Isabelle Durand; Jacques Banchereau; Pierre Miossec
The ability of synoviocytes to support terminal differentiation of activated B cells may explain plasma cell accumulation in rheumatoid synovium.
The Journal of clinical investigation 1995;95(2):456-63.
1995: Jacques Banchereau; B Dubois; J Fayette; N Burdin; Francine Brière; Pierre Miossec; Marie-Clotilde Rissoan; C van Kooten; Christophe Caux
Functional CD40 antigen on B cells, dendritic cells and fibroblasts.
Advances in experimental medicine and biology 1995;378():79-83.
1994: Pierre Miossec; P Chomarat; J Dechanet; Jean-François Moreau; Jean-Paul Roux; P Delmas; Jacques Banchereau
Interleukin-4 inhibits bone resorption through an effect on osteoclasts and proinflammatory cytokines in an ex vivo model of bone resorption in rheumatoid arthritis.
Arthritis and rheumatism 1994;37(12):1715-22.
1994: J Dechanet; Jean-Luc Taupin; P Chomarat; Marie-Clotilde Rissoan; Jean-François Moreau; Jacques Banchereau; Pierre Miossec
Interleukin-4 but not interleukin-10 inhibits the production of leukemia inhibitory factor by rheumatoid synovium and synoviocytes.
European journal of immunology 1994;24(12):3222-8.
1994: P Chomarat; J Kjeldsen-Kragh; A J Quayle; Jacob B Natvig; Pierre Miossec
Different cytokine production profiles of gamma delta T cell clones: relation to inflammatory arthritis.
European journal of immunology 1994;24(9):2087-91.
1994: Jacques Banchereau; Francine Brière; J P Galizzi; Pierre Miossec; F Rousset
Human interleukin 4.
Journal of lipid mediators and cell signalling 1994;9(1):43-53.
1993: J Dechanet; J Briolay; Marie-Clotilde Rissoan; P Chomarat; J P Galizzi; Jacques Banchereau; Pierre Miossec
IL-4 inhibits growth factor-stimulated rheumatoid synoviocyte proliferation by blocking the early phases of the cell cycle.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(9):4908-17.
1993: Pierre Miossec
Acting on the cytokine balance to control auto-immunity and chronic inflammation.
European cytokine network 1993;4(4):245-51.
1993: A J Quayle; P Chomarat; Pierre Miossec; J Kjeldsen-Kragh; Oystein T Førre; Jacob B Natvig
Rheumatoid inflammatory T-cell clones express mostly Th1 but also Th2 and mixed (Th0-like) cytokine patterns.
Scandinavian journal of immunology 1993;38(1):75-82.
1993: P Chomarat; J Briolay; Jacques Banchereau; Pierre Miossec
Increased production of soluble CD23 in rheumatoid arthritis, and its regulation by interleukin-4.
Arthritis and rheumatism 1993;36(2):234-42.
1993: P Chomarat; Marie-Clotilde Rissoan; Jacques Banchereau; Pierre Miossec
Interferon gamma inhibits interleukin 10 production by monocytes.
The Journal of experimental medicine 1993;177(2):523-7.
1992: Pierre Miossec; J Briolay; J Dechanet; J Wijdenes; H Martinez-Valdez; Jacques Banchereau
Inhibition of the production of proinflammatory cytokines and immunoglobulins by interleukin-4 in an ex vivo model of rheumatoid synovitis.
Arthritis and rheumatism 1992;35(8):874-83.
1992: J Briolay; J Dechanet; D Blanchard; Jacques Banchereau; Pierre Miossec
Interleukin 4 inhibits polyclonal immunoglobulin secretion and cytokine production by peripheral blood mononuclear cells from rheumatoid arthritis patients.
Journal of clinical immunology 1992;12(1):36-44.
1991: Jacques Banchereau; T Defrance; J P Galizzi; Pierre Miossec; F Rousset
Human interleukin 4.
Bulletin du cancer 1991;78(3):299-306.