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Montserrat Miralpeix

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Marcos Castillo; Montse Erra; Pilar Forns; Manel López; Mónica Maldonado; Marta Mir; Montserrat Miralpeix; Adelina Orellana; Isabel Ramis; Cristina Carreño; Bernat Vidal
Highly potent aminopyridines as Syk kinase inhibitors.
Mónica Aparici; Jorge Beleta; Carla Carcasona; Julio Cortijo; Jorge De Alba; Amadeu Gavaldà; Mireia Gómez-Angelats; Jordi Gras; Esteban J Morcillo; Raquel Otal; Carles Puig; Israel Ramos; Hamish Ryder; Dolors Vilella; Marisa Viñals; Montserrat Miralpeix
Pharmacological characterization of abediterol, a novel inhaled β(2)-adrenoceptor agonist with long duration of action and a favorable safety profile in preclinical models.
Pilar Forns; Manel López; Mónica Maldonado; Montserrat Miralpeix; Adelina Orellana; Isabel Ramis; Lorena Taboada; Juan Antonio Alonso; Cristina Carreño; Cristina Esteve; Bernat Vidal
Pyrazine-based Syk kinase inhibitors.

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All Publications

2012: Marcos Castillo; Montse Erra; Pilar Forns; Manel López; Mónica Maldonado; Marta Mir; Montserrat Miralpeix; Adelina Orellana; Isabel Ramis; Cristina Carreño; Bernat Vidal
Highly potent aminopyridines as Syk kinase inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(17):5419-23.
2012: Mónica Aparici; Jorge Beleta; Carla Carcasona; Julio Cortijo; Jorge De Alba; Amadeu Gavaldà; Mireia Gómez-Angelats; Jordi Gras; Esteban J Morcillo; Raquel Otal; Carles Puig; Israel Ramos; Hamish Ryder; Dolors Vilella; Marisa Viñals; Montserrat Miralpeix
Pharmacological characterization of abediterol, a novel inhaled β(2)-adrenoceptor agonist with long duration of action and a favorable safety profile in preclinical models.
The Journal of pharmacology and experimental therapeutics 2012;342(2):497-509.
2012: Pilar Forns; Manel López; Mónica Maldonado; Montserrat Miralpeix; Adelina Orellana; Isabel Ramis; Lorena Taboada; Juan Antonio Alonso; Cristina Carreño; Cristina Esteve; Bernat Vidal
Pyrazine-based Syk kinase inhibitors.
Bioorganic & medicinal chemistry letters 2012;22(8):2784-8.
2012: Javier Milara; Montserrat Miralpeix; Esteban J Morcillo; Teresa Peiró; Adela Serrano; Amadeu Gavaldà; Julio Cortijo
Aclidinium inhibits human lung fibroblast to myofibroblast transition.
Thorax 2012;67(3):229-37.
2012: Cristina Carreño; Anna Domènech; Montserrat Miralpeix; Neus Prats; Isabel Ramis
Characterization of a model of tracheal plasma extravasation in passively sensitized rats using anti-allergic and anti-inflammatory drugs by oral and intratracheal route.
Pulmonary pharmacology & therapeutics 2012;25(1):87-93.
2011: Joan Taltavull; Dolors Vilella; Hamish Ryder; Jordi Serrat; Míriam Andrés; Jorge Beleta; Elena Calama; Mònica Córdoba; Amadeu Gavaldà; Jordi Gràcia; Begoña Hernández; Montserrat Miralpeix; José Luis Montero; Lluís Pagès
Synthesis and biological activity of pyrido[3',2':4,5]furo[3,2-d]pyrimidine derivatives as novel and potent phosphodiesterase type 4 inhibitors.
European journal of medicinal chemistry 2011;46(10):4946-56.
2011: Maria Prat; Silvia Fonquerna; Amadeu Gavaldà; Montserrat Miralpeix
Inhaled muscarinic antagonists for respiratory diseases: a review of patents and current developments (2006 - 2010).
Expert opinion on therapeutic patents 2011;21(10):1543-73.
2011: Maria Prat; María Antonia Buil; Maria Dolors Fernández; Jordi Castro; Juan Manuel Monleón; Laia Tort; Gaspar Casals; Manuel Ferrer; Josep Maria Huerta; Sònia Espinosa; Manuel López; Victor Segarra; Amadeu Gavaldà; Montserrat Miralpeix; Israel Ramos; Dolors Vilella; Marisa González; Mònica Córdoba; Alvaro Cárdenas; Francisca Antón; Jorge Beleta; Hamish Ryder
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinyl carbamates as potent and long acting muscarinic antagonists.
Bioorganic & medicinal chemistry letters 2011;21(11):3457-61.
2011: Daniel Pérez; Maribel Crespo; Laia Solé; Maria Prat; Carla Carcasona; Elena Calama; Raquel Otal; Amadeu Gavaldá; Mireia Gómez-Angelats; Montserrat Miralpeix; Carles Puig
Discovery of substituted phenyl urea derivatives as novel long-acting β2-adrenoreceptor agonists.
Bioorganic & medicinal chemistry letters 2011;21(5):1545-8.
2010: Joan Taltavull; Jordi Serrat; Jordi Gràcia; Amadeu Gavaldà; Míriam Andrés; Mónica Córdoba; Montserrat Miralpeix; Dolors Vilella; Jorge Beleta; Hamish Ryder; Lluís Pagès
Synthesis and biological activity of pyrido[3',2':4,5]thieno[3,2-d]pyrimidines as phosphodiesterase type 4 inhibitors.
Journal of medicinal chemistry 2010;53(19):6912-22.
2010: Sonia Sentellas; Israel Ramos; Joan Albertí; Miquel Salvà; Francisca Antón; Montserrat Miralpeix; Jorge Beleta; Amadeu Gavaldà
Aclidinium bromide, a new, long-acting, inhaled muscarinic antagonist: in vitro plasma inactivation and pharmacological activity of its main metabolites.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2010;39(5):283-90.
2009: Amadeu Gavaldà; Montserrat Miralpeix; Israel Ramos; Raquel Otal; Cristina Carreño; Marisa Viñals; Teresa Doménech; Carla Carcasona; Blanca Reyes; Dolors Vilella; Jordi Gras; Julio Cortijo; Esteban J Morcillo; Jesús Llenas; Hamish Ryder; Jorge Beleta
Characterization of aclidinium bromide, a novel inhaled muscarinic antagonist, with long duration of action and a favorable pharmacological profile.
The Journal of pharmacology and experimental therapeutics 2009;331(2):740-51.
2009: María Prat; Dolors Fernández; M Antonia Buil; María I Crespo; Gaspar Casals; Manuel Ferrer; Laia Tort; Jordi Castro; Juan M Monleón; Amadeu Gavaldà; Montserrat Miralpeix; Israel Ramos; Teresa Doménech; Dolors Vilella; Francisca Antón; Josep M Huerta; Sonia Espinosa; Manuel López; Sonia Sentellas; Marisa González; Joan Albertí; Victor Segarra; Alvaro Cárdenas; Jorge Beleta; Hamish Ryder
Discovery of novel quaternary ammonium derivatives of (3R)-quinuclidinol esters as potent and long-acting muscarinic antagonists with potential for minimal systemic exposure after inhaled administration: identification of (3R)-3-{[hydroxy(di-2-thienyl)acetyl]oxy}-1-(3-phenoxypropyl)-1-azoniabicyclo[2.2.2]octane bromide (aclidinium bromide).
Journal of medicinal chemistry 2009;52(16):5076-92.
2009: Josep Bonjoch; Faïza DIABA; Lluís Pagès; Daniel Pérez; Lidia Soca; Montserrat Miralpeix; Dolors Vilella; Paquita Anton; Carles Puig
Synthesis and structure-activity relationships of gamma-carboline derivatives as potent and selective cysLT(1) antagonists.
Bioorganic & medicinal chemistry letters 2009;19(15):4299-302.
2005: Kristin J Carpenter; Jillian L Ewing; Jane M Schuh; Traci L Ness; Steven Kunkel; Monica Aparici; Montserrat Miralpeix; Cory M Hogaboam
Therapeutic targeting of CCR1 attenuates established chronic fungal asthma in mice.
British journal of pharmacology 2005;145(8):1160-72.
2005: Montserrat del Fresno; Dolors Fernández-Forner; Montserrat Miralpeix; Victor Segarra; Hamish Ryder; Miriam Royo; Fernando Albericio
Combinatorial approaches towards the discovery of new tryptase inhibitors.
Bioorganic & medicinal chemistry letters 2005;15(6):1659-64.
2005: Silvia Fonquerna; Montserrat Miralpeix; Lluís Pagès; Carles Puig; Arantxa Cardús; Francisca Antón; Dolors Vilella; Mónica Aparici; José Prieto; Graham Warrellow; Jorge Beleta; Hamish Ryder
Synthesis and structure-activity relationships of piperidinylpyrrolopyridine derivatives as potent and selective H1 antagonists.
Bioorganic & medicinal chemistry letters 2005;15(4):1165-7.
2004: Silvia Fonquerna; Montserrat Miralpeix; Lluís Pagès; Carles Puig; Arantxa Cardús; Francisca Antón; Alvaro Cárdenas; Dolors Vilella; Mónica Aparici; Elena Calaf; José Prieto; Jordi Gras; Josep M Huerta; Graham Warrellow; Jorge Beleta; Hamish Ryder
Synthesis and structure-activity relationships of novel histamine H1 antagonists: indolylpiperidinyl benzoic acid derivatives.
Journal of medicinal chemistry 2004;47(25):6326-37.
2004: Xavier Romero Ros; Daniel Benítez; Sandra March; Ramón Vilella; Montserrat Miralpeix; Pablo Engel
Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4).
Tissue antigens 2004;64(2):132-44.
2004: Mónica García; Xavier del Rio; Sandra Silvestre; Mario Rubiralta; Estrella Lozoya; Victor Segarra; Dolors Fernández; Montserrat Miralpeix; Mónica Aparici; Anna Diez
Design, synthesis and biological activity of a targeted library of potential tryptase inhibitors.
Organic & biomolecular chemistry 2004;2(11):1633-42.
2000: A Martínez; Ana Castro; Carmen Gil; Montserrat Miralpeix; Victor Segarra; T Doménech; Jorge Beleta; José M Palacios; Hamish Ryder; Xavier Miró; C Bonet; Josep M Casacuberta; Fernando Azorín; Benjamin Piña; P Puigdoménech
Benzyl derivatives of 2,1,3-benzo- and benzothieno[3,2-a]thiadiazine 2,2-dioxides: first phosphodiesterase 7 inhibitors.
Journal of medicinal chemistry 2000;43(4):683-9.
2000: Carles Puig; María I Crespo; Nuria Godessart; J Feixas; J Ibarzo; Juan-Miguel Jiménez; Lídia Soca; I Cardelús; A Heredia; Montserrat Miralpeix; J Puig; Jorge Beleta; J M Huerta; M López; Victor Segarra; Hamish Ryder; José M Palacios
Synthesis and biological evaluation of 3,4-diaryloxazolones: A new class of orally active cyclooxygenase-2 inhibitors.
Journal of medicinal chemistry 2000;43(2):214-23.
1998: María I Crespo; Lluís Pagès; A Vega; Victor Segarra; M López; T Doménech; Montserrat Miralpeix; Jorge Beleta; Hamish Ryder; José M Palacios
Design, synthesis, and biological activities of new thieno[3,2-d] pyrimidines as selective type 4 phosphodiesterase inhibitors.
Journal of medicinal chemistry 1998;41(21):4021-35.
1998: Victor Segarra; María I Crespo; F Pujol; Jorge Beleta; T Doménech; Montserrat Miralpeix; José M Palacios; Ana Castro; Ana Martinez
Phosphodiesterase inhibitory properties of losartan. Design and synthesis of new lead compounds.
Bioorganic & medicinal chemistry letters 1998;8(5):505-10.
1998: M C Collado; Jorge Beleta; E Martinez; Montserrat Miralpeix; T Domènech; José M Palacios; J Hernández
Functional and biochemical evidence for diazepam as a cyclic nucleotide phosphodiesterase type 4 inhibitor.
British journal of pharmacology 1998;123(6):1047-54.
1997: Montserrat Miralpeix; Mercedes Camacho; J López-Belmonte; F Canalías; Jorge Beleta; José M Palacios; Luís Vila
Selective induction of cyclo-oxygenase-2 activity in the permanent human endothelial cell line HUV-EC-C: biochemical and pharmacological characterization.
British journal of pharmacology 1997;121(2):171-80.