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Károly Mirnics

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Libin Xu; Dale A Rosado; Zeljka Korade; Károly Mirnics; Ned A Porter
Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells.
Zeljka Korade; Károly Mirnics; Libin Xu; Ned A Porter
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome.
Rehana K Leak; Károly Mirnics; Zhiming Zhang; Amanda M Dettmer; Krassimira A Garbett; Judy L Cameron
Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates.

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All Publications

2013: Libin Xu; Dale A Rosado; Zeljka Korade; Károly Mirnics; Ned A Porter
Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells.
Journal of lipid research 2013;54(4):1135-43.
2013: Zeljka Korade; Károly Mirnics; Libin Xu; Ned A Porter
Lipid biomarkers of oxidative stress in a genetic mouse model of Smith-Lemli-Opitz syndrome.
Journal of inherited metabolic disease 2013;36(1):113-22.
2012: Rehana K Leak; Károly Mirnics; Zhiming Zhang; Amanda M Dettmer; Krassimira A Garbett; Judy L Cameron
Physical activity is linked to ceruloplasmin in the striatum of intact but not MPTP-treated primates.
Cell and tissue research 2012;350(3):401-7.
2012: Xulun Zhang; Karthikeyan Veeraraghavalu; Brian Wilburn; Krassimira Garbett; Reid Gilmore; Károly Mirnics; Sangram S Sisodia
A role for presenilins in autophagy revisited: normal acidification of lysosomes in cells lacking PSEN1 and PSEN2.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(25):8633-48.
2012: Amanda C Mitchell; Michael J Zigmond; Judy L Cameron; Rehana K Leak; Károly Mirnics
Gene transcripts associated with BMI in the motor cortex and caudate nucleus of calorie restricted rhesus monkeys.
Genomics 2012;99(3):144-51.
2012: Libin Xu; Aaron B Bowman; Jennifer Da; Wei Liu; Károly Mirnics; Ned A Porter; Zeljka Korade
DHCEO accumulation is a critical mediator of pathophysiology in a Smith-Lemli-Opitz syndrome model.
Neurobiology of disease 2012;45(3):923-9.
2012: Amanda C Mitchell; Michael J Zigmond; Judy L Cameron; Krassimira A Garbett; Rehana K Leak; Károly Mirnics
Physical activity-associated gene expression signature in nonhuman primate motor cortex.
Obesity (Silver Spring, Md.) 2012;20(3):692-8.
2012: Krassimira A Garbett; E Y Hsiao; S Kálmán; P H Patterson; Károly Mirnics
Effects of maternal immune activation on gene expression patterns in the fetal brain.
Translational psychiatry 2012;2():e98.
2012: Amanda C Mitchell; Károly Mirnics
Gene expression profiling of the brain: pondering facts and fiction.
Neurobiology of disease 2012;45(1):3-7.
2011: Zeljka Korade; Károly Mirnics
Wnt signaling as a potential therapeutic target for frontotemporal dementia.
Neuron 2011;71(6):955-7.
2011: R C Shelton; M Sidoryk-Wegrzynowicz; R Reddy; M Aschner; J Claiborne; D A Lewis; Károly Mirnics
Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression.
Molecular psychiatry 2011;16(7):751-62.
2011: Zeljka Korade; Károly Mirnics
Gene expression: The autism disconnect.
Nature 2011;474(7351):294-5.
2011: Gábor Faludi; Károly Mirnics
Synaptic changes in the brain of subjects with schizophrenia.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2011;29(3):305-9.
2011: Károly Mirnics
Schizophrenia. Special issue introduction.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2011;29(3):189-91.
2011: Szatmár Horváth; Zoltán Janka; Károly Mirnics
Analyzing schizophrenia by DNA microarrays.
Biological psychiatry 2011;69(2):157-62.
2010: Amanda C Mitchell; Georgina Aldridge; Shawn Kohler; Greg Stanton; Elinor Sullivan; Krassimira Garbett; Gabor Faludi; Károly Mirnics; Judy L Cameron; William Greenough
Molecular correlates of spontaneous activity in non-human primates.
Journal of neural transmission (Vienna, Austria : 1996) 2010;117(12):1353-8.
2010: Krassimira A Garbett; S Horváth; Philip J Ebert; M J Schmidt; K Lwin; A Mitchell; Pat Levitt; Károly Mirnics
Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression.
Molecular psychiatry 2010;15(10):987-95.
2010: Dominique Arion; Szatmár Horváth; David A Lewis; Károly Mirnics
Infragranular gene expression disturbances in the prefrontal cortex in schizophrenia: signature of altered neural development?
Neurobiology of disease 2010;37(3):738-46.
2009: Michael Zigmond; Judy L Cameron; Rehana K Leak; Károly Mirnics; Vivienne A Russell; Richard J Smeyne; Amanda D Smith
Triggering endogenous neuroprotective processes through exercise in models of dopamine deficiency.
Parkinsonism & related disorders 2009;15 Suppl 3():S42-5.
2009: Zeljka Korade; Rajappa S Kenchappa; Károly Mirnics; Bruce D Carter
NRIF is a regulator of neuronal cholesterol biosynthesis genes.
Journal of molecular neuroscience : MN 2009;38(2):152-8.
2009: Szatmár Horváth; Károly Mirnics
Breaking the gene barrier in schizophrenia.
Nature medicine 2009;15(5):488-90.
2009: Zeljka Korade; Anne K Kenworthy; Károly Mirnics
Molecular consequences of altered neuronal cholesterol biosynthesis.
Journal of neuroscience research 2009;87(4):866-75.
2008: Károly Mirnics
What is in the brain soup?
Nature neuroscience 2008;11(11):1237-8.
2008: Krassimira Garbett; Philip J Ebert; Amanda Mitchell; Carla Lintas; Barbara Manzi; Károly Mirnics; Antonio M Persico
Immune transcriptome alterations in the temporal cortex of subjects with autism.
Neurobiology of disease 2008;30(3):303-11.
2008: Takanori Hashimoto; H Holly Bazmi; Károly Mirnics; Qiang Wu; Allan R Sampson; David A Lewis
Conserved regional patterns of GABA-related transcript expression in the neocortex of subjects with schizophrenia.
The American journal of psychiatry 2008;165(4):479-89.
2008: Krassimira Garbett; Rodica Gal-Chis; Gabor Gaszner; David A Lewis; Károly Mirnics
Transcriptome alterations in the prefrontal cortex of subjects with schizophrenia who committed suicide.
Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakológiai Egyesület lapja = official journal of the Hungarian Association of Psychopharmacology 2008;10(1):9-14.
2008: Takanori Hashimoto; Dominique Arion; Travis Unger; J G Maldonado-Avilés; H M Morris; David W Volk; Károly Mirnics; David A Lewis
Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia.
Molecular psychiatry 2008;13(2):147-61.
2008: Károly Mirnics; Eric M Norstrom; Krassimira Garbett; Se Hoon Choi; Xiaoqiong Zhang; Philip Ebert; Sangram S Sisodia
Molecular signatures of neurodegeneration in the cortex of PS1/PS2 double knockout mice.
Molecular neurodegeneration 2008;3():14.
2008: Kodavali V Chowdari; Mikhil Bamne; Joel Wood; Michael E Talkowski; Károly Mirnics; Pat Levitt; David A Lewis; Vishwajit L Nimgaonkar
Linkage disequilibrium patterns and functional analysis of RGS4 polymorphisms in relation to schizophrenia.
Schizophrenia bulletin 2008;34(1):118-26.
2007: Stephen E P Smith; Jennifer Li; Krassimira Garbett; Károly Mirnics; Paul H Patterson
Maternal immune activation alters fetal brain development through interleukin-6.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(40):10695-702.
2007: Ranjan Dutta; Jennifer McDonough; Ansi Chang; Lakshman Swamy; Alan Siu; Grahame J Kidd; Richard A Rudick; Károly Mirnics; Bruce D Trapp
Activation of the ciliary neurotrophic factor (CNTF) signalling pathway in cortical neurons of multiple sclerosis patients.
Brain : a journal of neurology 2007;130(Pt 10):2566-76.
2007: Dominique Arion; Travis Unger; David A Lewis; Pat Levitt; Károly Mirnics
Molecular evidence for increased expression of genes related to immune and chaperone function in the prefrontal cortex in schizophrenia.
Biological psychiatry 2007;62(7):711-21.
2007: Tunda Hidvegi; Károly Mirnics; Pamela Hale; Michael Ewing; Caroline Beckett; David H Perlmutter
Regulator of G Signaling 16 is a marker for the distinct endoplasmic reticulum stress state associated with aggregated mutant alpha1-antitrypsin Z in the classical form of alpha1-antitrypsin deficiency.
The Journal of biological chemistry 2007;282(38):27769-80.
2007: Daniel B Campbell; Rosanna D'Oronzio; Krassi Garbett; Philip J Ebert; Károly Mirnics; Pat Levitt; Antonio M Persico
Disruption of cerebral cortex MET signaling in autism spectrum disorder.
Annals of neurology 2007;62(3):243-50.
2007: Kodavali V Chowdari; A Northup; Lora Pless; Joel Wood; Y H Joo; Károly Mirnics; D A Lewis; Pat Levitt; Silviu-Alin Bacanu; Vishwajit L Nimgaonkar
DNA pooling: a comprehensive, multi-stage association analysis of ACSL6 and SIRT5 polymorphisms in schizophrenia.
Genes, brain, and behavior 2007;6(3):229-39.
2007: Michael Sabatini; Philip J Ebert; David A Lewis; Pat Levitt; Judy L Cameron; Károly Mirnics
Amygdala gene expression correlates of social behavior in monkeys experiencing maternal separation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(12):3295-304.
2007: Dominique Arion; Travis Unger; David A Lewis; Károly Mirnics
Molecular markers distinguishing supragranular and infragranular layers in the human prefrontal cortex.
The European journal of neuroscience 2007;25(6):1843-54.
2006: Pat Levitt; Philip J Ebert; Károly Mirnics; Vishwajit L Nimgaonkar; David A Lewis
Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4).
Biological psychiatry 2006;60(6):534-7.
2006: H Richard Koerber; Károly Mirnics; Jeffrey J Lawson
Synaptic plasticity in the adult spinal dorsal horn: the appearance of new functional connections following peripheral nerve regeneration.
Experimental neurology 2006;200(2):468-79.
2006: Károly Mirnics; Pat Levitt; David A Lewis
Critical appraisal of DNA microarrays in psychiatric genomics.
Biological psychiatry 2006;60(2):163-76.
2006: C Glorioso; Michael Sabatini; Travis Unger; T Hashimoto; Lisa M Monteggia; David A Lewis; Károly Mirnics
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood.
Molecular psychiatry 2006;11(7):633-48.
2006: Dominique Arion; Michael Sabatini; Travis Unger; Jesús Pastor; Lidia Alonso-Nanclares; Inmaculada Ballesteros-Yáñez; Rafael García Sola; Alberto Muñoz; Károly Mirnics; Javier DeFelipe
Correlation of transcriptome profile with electrical activity in temporal lobe epilepsy.
Neurobiology of disease 2006;22(2):374-87.
2006: Deborah Hollingshead; Zeljka Korade; David A Lewis; Pat Levitt; Károly Mirnics
DNA self-polymers as microarray probes improve assay sensitivity.
Journal of neuroscience methods 2006;151(2):216-23.
2006: Ranjan Dutta; Jennifer McDonough; Xinghua Yin; John Peterson; Ansi Chang; Thalia Torres; Tatyana I Gudz; Wendy B Macklin; David A Lewis; Robert J Fox; Richard A Rudick; Károly Mirnics; Bruce D Trapp
Mitochondrial dysfunction as a cause of axonal degeneration in multiple sclerosis patients.
Annals of neurology 2006;59(3):478-89.
2006: David A Lewis; Károly Mirnics
Transcriptome alterations in schizophrenia: disturbing the functional architecture of the dorsolateral prefrontal cortex.
Progress in brain research 2006;158():141-52.
2006: Stephen D. Ginsberg; Károly Mirnics
Functional genomic methodologies.
Progress in brain research 2006;158():15-40.
2005: Travis Unger; Zeljka Korade; Orly Lazarov; David Terrano; Nina F Schor; Sangram S Sisodia; Károly Mirnics
Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(12):1041-51.
2005: Zeljka Korade Mirnics; Chaohua Yan; Carmel Portugal; TAE-WAN KIM; H Uri Saragovi; Sangram S Sisodia; Károly Mirnics; Nina F Schor
P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1.
Neurobiology of disease 2005;20(3):969-85.
2005: Travis Unger; Zeljka Korade; Orly Lazarov; David Terrano; Sangram S Sisodia; Károly Mirnics
True and false discovery in DNA microarray experiments: transcriptome changes in the hippocampus of presenilin 1 mutant mice.
Methods (San Diego, Calif.) 2005;37(3):261-73.
2005: Frank A Middleton; Lansha Peng; David A Lewis; Pat Levitt; Károly Mirnics
Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2005;30(5):974-83.
2005: Deborah Hollingshead; David A Lewis; Károly Mirnics
Platform influence on DNA microarray data in postmortem brain research.
Neurobiology of disease 2005;18(3):649-55.
2005: Orly Lazarov; John Robinson; Ya-Ping Tang; Ilana S Hairston; Zeljka Korade-Mirnics; Virginia M-Y Lee; Louis B Hersh; Robert M Sapolsky; Károly Mirnics; Sangram S Sisodia
Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice.
Cell 2005;120(5):701-13.
2005: Károly Mirnics; Zeljka Korade; Dominique Arion; Orly Lazarov; Travis Unger; Melissa Macioce; Michael Sabatini; David Terrano; Katherine C Douglass; Nina F Schor; Sangram S Sisodia
Presenilin-1-dependent transcriptome changes.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(6):1571-8.
2004: Julie L Pongrac; Frank A Middleton; Lansha Peng; David A Lewis; Pat Levitt; Károly Mirnics
Heat shock protein 12A shows reduced expression in the prefrontal cortex of subjects with schizophrenia.
Biological psychiatry 2004;56(12):943-50.
2004: Károly Mirnics; Jonathan Pevsner
Progress in the use of microarray technology to study the neurobiology of disease.
Nature neuroscience 2004;7(5):434-9.
2004: Zeljka Korade Mirnics; Eva Caudell; YanHua Gao; Kazuhiko Kuwahara; Nobuo Sakaguchi; Tomohiro Kurosaki; Joan Burnside; Károly Mirnics; Seth J Corey
Microarray analysis of Lyn-deficient B cells reveals germinal center-associated nuclear protein and other genes associated with the lymphoid germinal center.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(7):4133-41.
2004: Károly Mirnics; Pat Levitt; David A Lewis
DNA microarray analysis of postmortem brain tissue.
International review of neurobiology 2004;60():153-81.
2003: Zeljka Korade Mirnics; Károly Mirnics; David Terrano; D A Lewis; Sangram S Sisodia; Nina F Schor
DNA microarray profiling of developing PS1-deficient mouse brain reveals complex and coregulated expression changes.
Molecular psychiatry 2003;8(10):863-78.
2003: Takanori Hashimoto; David W Volk; Stephen M Eggan; Károly Mirnics; Joseph N Pierri; Zhuoxin Sun; Allan R Sampson; David A Lewis
Gene expression deficits in a subclass of GABA neurons in the prefrontal cortex of subjects with schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(15):6315-26.
2002: Julie Pongrac; Frank A Middleton; David A Lewis; Pat Levitt; Károly Mirnics
Gene expression profiling with DNA microarrays: advancing our understanding of psychiatric disorders.
Neurochemical research 2002;27(10):1049-63.
2002: Kodavali V Chowdari; Károly Mirnics; Prachi Semwal; Joel Wood; Elizabeth Lawrence; Triptish Bhatia; Smita N Deshpande; Thelma B K; Robert E Ferrell; Frank A Middleton; Bernie Devlin; Pat Levitt; David A Lewis; Vishwajit L Nimgaonkar
Association and linkage analyses of RGS4 polymorphisms in schizophrenia.
Human molecular genetics 2002;11(12):1373-80.
2002: Frank A Middleton; Károly Mirnics; Joseph N Pierri; David A Lewis; Pat Levitt
Gene expression profiling reveals alterations of specific metabolic pathways in schizophrenia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2002;22(7):2718-29.
2001: Károly Mirnics; Frank A Middleton; David A Lewis; Pat Levitt
The human genome: gene expression profiling and schizophrenia.
The American journal of psychiatry 2001;158(9):1384.
2001: Károly Mirnics; Frank A Middleton; David A Lewis; Pat Levitt
Analysis of complex brain disorders with gene expression microarrays: schizophrenia as a disease of the synapse.
Trends in neurosciences 2001;24(8):479-86.
2001: Károly Mirnics
Microarrays in brain research: the good, the bad and the ugly.
Nature reviews. Neuroscience 2001;2(6):444-7.
2001: Károly Mirnics; Frank A Middleton; Gregg D Stanwood; David A Lewis; Pat Levitt
Disease-specific changes in regulator of G-protein signaling 4 (RGS4) expression in schizophrenia.
Molecular psychiatry 2001;6(3):293-301.
2001: Károly Mirnics; Frank A Middleton; David A Lewis; Pat Levitt
Delineating novel signature patterns of altered gene expression in schizophrenia using gene microarrays.
TheScientificWorldJournal 2001;1():114-6.
2000: Károly Mirnics; Frank A Middleton; A Marquez; David A Lewis; Pat Levitt
Molecular characterization of schizophrenia viewed by microarray analysis of gene expression in prefrontal cortex.
Neuron 2000;28(1):53-67.
1999: H Richard Koerber; Károly Mirnics; A M Kavookjian; Alan R Light
Ultrastructural analysis of ectopic synaptic boutons arising from peripherally regenerated primary afferent fibers.
Journal of neurophysiology 1999;81(4):1636-44.
1997: Károly Mirnics; H Richard Koerber
Properties of individual embryonic primary afferents and their spinal projections in the rat.
Journal of neurophysiology 1997;78(3):1590-600.
1996: H Richard Koerber; Károly Mirnics
Plasticity of dorsal horn cell receptive fields after peripheral nerve regeneration.
Journal of neurophysiology 1996;75(6):2255-67.
1995: H Richard Koerber; Károly Mirnics
Morphology of functional long-ranging primary afferent projections in the cat spinal cord.
Journal of neurophysiology 1995;74(6):2336-48.
1995: Károly Mirnics; H Richard Koerber
Prenatal development of rat primary afferent fibers: II. Central projections.
The Journal of comparative neurology 1995;355(4):601-14.
1995: Károly Mirnics; H Richard Koerber
Prenatal development of rat primary afferent fibers: I. Peripheral projections.
The Journal of comparative neurology 1995;355(4):589-600.
1995: H Richard Koerber; Károly Mirnics; Lorne Mendell
Properties of regenerated primary afferents and their functional connections.
Journal of neurophysiology 1995;73(2):693-702.
1994: H Richard Koerber; Károly Mirnics; Paul B Brown; Lorne Mendell
Central sprouting and functional plasticity of regenerated primary afferents.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1994;14(6):3655-71.