FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jon Mirsalis

Research Profile

Living Beings

Anatomy

Chemicals & Drugs

Procedures

Physiology

Disorders

Liver Neoplasms, Experimental

Co-author Network

Publications

TOP 3
Xiaohua Zhu; W David Wilson; Sihyung Yang; Moloy Banerjee; David W Boykin; Denise da Gama Jaen Batista; Cristiane França da Silva; Maria de Nazaré Correia Soeiro; Abdelbasset Farahat; Carol E Green; Qiang Liu; Elen Mello de Souza; Jon C Mirsalis; Manoj Munde; Toufan Parman; Chad E Stephens; Michael Zhuo Wang; Karl A Werbovetz
Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
John E Coughlin; Carol E Green; Judith Marquis; Jon C Mirsalis; Kathleen G O'Loughlin; Seetharamaiyer Padmanabhan; Rajendra K Pandey; Radhakrishnan P Iyer
Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate.
Rupa Doppalapudi; Edward S Riccio; Linda L Rausch; Julie A Shimon; Pamela S Lee; Kristien E Mortelmans; Izet M Kapetanovic; James A Crowell; Jon C Mirsalis
Evaluation of chemopreventive agents for genotoxic activity.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jon Mirsalis (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Xiaohua Zhu; W David Wilson; Sihyung Yang; Moloy Banerjee; David W Boykin; Denise da Gama Jaen Batista; Cristiane França da Silva; Maria de Nazaré Correia Soeiro; Abdelbasset Farahat; Carol E Green; Qiang Liu; Elen Mello de Souza; Jon C Mirsalis; Manoj Munde; Toufan Parman; Chad E Stephens; Michael Zhuo Wang; Karl A Werbovetz
Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
Antimicrobial agents and chemotherapy 2012;56(7):3690-9.
2012: John E Coughlin; Carol E Green; Judith Marquis; Jon C Mirsalis; Kathleen G O'Loughlin; Seetharamaiyer Padmanabhan; Rajendra K Pandey; Radhakrishnan P Iyer
Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-hepatitis B virus dinucleoside phosphorothioate.
Drug metabolism and disposition: the biological fate of chemicals 2012;40(5):970-81.
2007: Rupa Doppalapudi; Edward S Riccio; Linda L Rausch; Julie A Shimon; Pamela S Lee; Kristien E Mortelmans; Izet M Kapetanovic; James A Crowell; Jon C Mirsalis
Evaluation of chemopreventive agents for genotoxic activity.
Mutation research 2007;629(2):148-60.
2006: Rikki N Waterhouse; Jun Zhao; Michael G Stabin; Hanna Ng; Janice Schindler-Horvat; Raymond Chee-Seing Chang; Jon C Mirsalis
Preclinical acute toxicity studies and dosimetry estimates of the novel sigma-1 receptor radiotracer, [18F]SFE.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2006;8(5):284-91.
2005: Hanna H Ng; Christopher E Frantz; Linda Rausch; David Fairchild; Julie A Shimon; Edward S Riccio; Sherrod Smith; Jon C Mirsalis
Gene expression profiling of mouse host response to Listeria monocytogenes infection.
Genomics 2005;86(6):657-67.
2005: Jon C Mirsalis; Julie A Shimon; Alphonso Johnson; David Fairchild; Nathan Kanazawa; Tung Nguyen; Johan de Boer; Barry W Glickman; Richard A Winegar
Evaluation of mutant frequencies of chemically induced tumors and normal tissues in lambda/cII transgenic mice.
Environmental and molecular mutagenesis 2005;45(1):17-35.
2004: Sandhya Ramanathan-Girish; Paul Catz; Moire R Creek; Benjamin Wu; David Thomas; Donald J Krogstad; Dibyendu De; Jon C Mirsalis; Carol E Green
Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques.
International journal of toxicology 2004;23(3):179-89.
2003: Veronique Thybaud; Stephen Dean; Takehiko Nohmi; Johan de Boer; George R Douglas; Barry W Glickman; Nancy J Gorelick; John A Heddle; Robert H Heflich; Iain B Lambert; Hans-Jörg Martus; Jon C Mirsalis; Takayoshi Suzuki; Nobuhiro Yajima
In vivo transgenic mutation assays.
Mutation research 2003;540(2):141-51.
2003: Jon C Mirsalis; Janice Schindler-Horvat; James R Hill; Carol E Green; Chozo Mitoma; Joseph E Tomaszewski; Charles A Tyson; Susan J Donohue
Toxicity of a quinocarmycin analog, DX-52-1, in rats and dogs in relation to clinical outcome.
Cancer chemotherapy and pharmacology 2003;51(3):193-201.
2003: Polly Y Chang; Jon C Mirsalis; Edward S Riccio; James P Bakke; Pamela S Lee; Julie A Shimon; Sandra Phillips; David Fairchild; Yukihiko Hara; James A Crowell
Genotoxicity and toxicity of the potential cancer-preventive agent polyphenon E.
Environmental and molecular mutagenesis 2003;41(1):43-54.
2002: R Rita Misra; Stephen D Hursting; Susan N Perkins; N Sathyamoorthy; Jon C Mirsalis; Edward S Riccio; James A Crowell
Genotoxicity and carcinogenicity studies of soy isoflavones.
International journal of toxicology 2002;21(4):277-85.
2001: Edward S Riccio; Pamela S Lee; Richard A Winegar; Donald J Krogstad; Dibyendu De; Jon C Mirsalis
Genetic toxicology testing of the antimalarial drugs chloroquine and a new analog, AQ-13.
Environmental and molecular mutagenesis 2001;38(1):69-79.
2000: Judith MacGregor; C M Hamilton; J E Kubicek; Jon C Mirsalis
Pyridine does not induce unscheduled DNA synthesis (UDS) in hepatocytes of male B6C3F1 mice treated in vivo.
Journal of applied toxicology : JAT 2000;20(5):389-93.
2000: Yvonne R Freund; Jon C Mirsalis; D G Fairchild; J Brune; L A Hokama; Janice Schindler-Horvat; Joseph E Tomaszewski; James W Hodge; Jeffrey Schlom; Judith A Kantor; Charles A Tyson; Susan J Donohue
Vaccination with a recombinant vaccinia vaccine containing the B7-1 co-stimulatory molecule causes no significant toxicity and enhances T cell-mediated cytotoxicity.
International journal of cancer. Journal international du cancer 2000;85(4):508-17.
2000: John A Heddle; S Dean; Takehiko Nohmi; ME Boerrigter; D Casciano; George R Douglas; Barry W Glickman; Nancy J Gorelick; Jon C Mirsalis; H J Martus; Thomas R Skopek; Veronique Thybaud; Kenneth Tindall; N Yajima
In vivo transgenic mutation assays.
Environmental and molecular mutagenesis 2000;35(3):253-9.
1999: Johan G de Boer; Jon C Mirsalis; Barry W Glickman
Mutational spectrum of dimethylnitrosamine in the liver of 3- and 6-week-old lacI transgenic mice.
Environmental and molecular mutagenesis 1999;34(2-3):80-3.
1999: Jon C Mirsalis; Janice Schindler-Horvat; J R Hill; Joseph E Tomaszewski; Susan J Donohue; Charles A Tyson
Toxicity of dolastatin 10 in mice, rats and dogs and its clinical relevance.
Cancer chemotherapy and pharmacology 1999;44(5):395-402.
1999: SW Dean; T M Brooks; Brian Burlinson; Jon C Mirsalis; Brian Myhr; L Recio; Veronique Thybaud
Transgenic mouse mutation assay systems can play an important role in regulatory mutagenicity testing in vivo for the detection of site-of-contact mutagens.
Mutagenesis 1999;14(1):141-51.
1998: J H Sherman; R S Nair; K L Steinmetz; Jon C Mirsalis; E R Nestmann; J A Barter
Evaluation of unscheduled DNA synthesis (UDS) and replicative DNA synthesis (RDS) following treatment of rats and mice with p-dichlorobenzene.
Teratogenesis, carcinogenesis, and mutagenesis 1998;18(6):309-18.
1997: Richard A Winegar; G Carr; Jon C Mirsalis
Analysis of the mutagenic potential of ENU and MMS in germ cells of male C57BL/6 lacI transgenic mice.
Mutation research 1997;388(2-3):175-8.
1997: C M Hamilton; Jack Dabbs; G D Cunningham; L A Vernetti; Jon C Mirsalis; R D Snyder
Evaluation of positive controls for the in vitro unscheduled DNA synthesis assay using hepatocytes from induced (Aroclor 1254) and uninduced male cynomolgus monkey.
Environmental and molecular mutagenesis 1997;30(3):354-8.
1996: Johan G de Boer; Jon C Mirsalis; G S Provost; Kenneth Tindall; Barry W Glickman
Spectrum of mutations in kidney, stomach, and liver from lacI transgenic mice recovered after treatment with tris(2,3-dibromopropyl)phosphate.
Environmental and molecular mutagenesis 1996;28(4):418-23.
1996: G S Provost; Jon C Mirsalis; B J Rogers; Jay Short
Mutagenic response to benzene and tris(2,3-dibromopropyl)-phosphate in the lambda lacI transgenic mouse mutation assay: a standardized approach to in vivo mutation analysis.
Environmental and molecular mutagenesis 1996;28(4):342-7.
1996: Jon C Mirsalis; C M Hamilton; K G O'Loughlin; Dennis J Paustenbach; Brent D Kerger; S Patierno
Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays.
Environmental and molecular mutagenesis 1996;28(1):60-3.
1995: Jon C Mirsalis
Transgenic models for detection of mutations in tumors and normal tissues of rodents.
Toxicology letters 1995;82-83():131-4.
1995: Jon C Mirsalis; J A Monforte; R A Winegar
Transgenic animal models for detection of in vivo mutations.
Annual review of pharmacology and toxicology 1995;35():145-64.
1994: R A Winegar; L H Lutze; J D Hamer; K G O'Loughlin; Jon C Mirsalis
Radiation-induced point mutations, deletions and micronuclei in lacI transgenic mice.
Mutation research 1994;307(2):479-87.
1994: Jon C Mirsalis; J A Monforte; R A Winegar
Transgenic animal models for measuring mutations in vivo.
Critical reviews in toxicology 1994;24(3):255-80.
1993: Jon C Mirsalis; C M Hamilton; J E Schindler; C E Green; Jack Dabbs
Effects of soya bean flakes and liquorice root extract on enzyme induction and toxicity in B6C3F1 mice.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1993;31(5):343-50.
1993: Jon C Mirsalis; G S Provost; C D Matthews; R T Hamner; J E Schindler; K G O'Loughlin; James T MacGregor; Jay Short
Induction of hepatic mutations in lacI transgenic mice.
Mutagenesis 1993;8(3):265-71.
1993: Jon C Mirsalis; K L Steinmetz; W F Blazak; J W Spalding
Evaluation of the potential of riddelliine to induce unscheduled DNA synthesis, S-phase synthesis, or micronuclei following in vivo treatment with multiple doses.
Environmental and molecular mutagenesis 1993;21(3):265-71.
1990: Jon C Mirsalis; K L Steinmetz; C M Hamilton; J P Bakke; K E Garin
The role of cell proliferation in chemical carcinogenesis.
Progress in clinical and biological research 1990;340D():113-22.
1990: Jon C Mirsalis; K L Steinmetz
The role of hyperplasia in liver carcinogenesis.
Progress in clinical and biological research 1990;331():149-61.
1989: CS Aaron; Philip R Harbach; K L Steinmetz; J P Bakke; Jon C Mirsalis
The in vitro unscheduled DNA synthesis (UDS) assay in rat primary hepatocytes: evaluation of 24 drug candidates.
Mutation research 1989;223(2):141-51.
1989: CS Aaron; L F Stankowski; Philip R Harbach; R Valencia; J K Mayo; Jon C Mirsalis; J H Mazurek; K L Steinmetz; S K Wiser; DM Zimmer
Comparative mutagenicity testing of a drug candidate, U-48753E: mechanism of induction of gene mutations in mammalian cells and quantitation of potential hazard.
Mutation research 1989;223(2):111-20.
1989: Jon C Mirsalis; C K Tyson; K L Steinmetz; E K Loh; C M Hamilton; J P Bakke; J W Spalding
Measurement of unscheduled DNA synthesis and S-phase synthesis in rodent hepatocytes following in vivo treatment: testing of 24 compounds.
Environmental and molecular mutagenesis 1989;14(3):155-64.
1988: K L Steinmetz; C E Green; J P Bakke; D K Spak; Jon C Mirsalis
Induction of unscheduled DNA synthesis in primary cultures of rat, mouse, hamster, monkey, and human hepatocytes.
Mutation research 1988;206(1):91-102.
1988: K L Steinmetz; C K Tyson; E F Meierhenry; J W Spalding; Jon C Mirsalis
Examination of genotoxicity, toxicity and morphologic alterations in hepatocytes following in vivo or in vitro exposure to methapyrilene.
Carcinogenesis 1988;9(6):959-63.
1987: C M Hamilton; Jon C Mirsalis
Factors that affect the sensitivity of the in vivo-in vitro hepatocyte DNA repair assay in the male rat.
Mutation research 1987;189(3):341-7.
1987: Jon C Mirsalis
In vivo measurement of unscheduled DNA synthesis and S-phase synthesis as an indicator of hepatocarcinogenesis in rodents.
Cell biology and toxicology 1987;3(2):165-73.
1985: Jon C Mirsalis; C K Tyson; E N Loh; K L Steinmetz; J P Bakke; C M Hamilton; D K Spak; J W Spalding
Induction of hepatic cell proliferation and unscheduled DNA synthesis in mouse hepatocytes following in vivo treatment.
Carcinogenesis 1985;6(10):1521-4.
1985: C K Tyson; Jon C Mirsalis
Measurement of unscheduled DNA synthesis in rat kidney cells following in vivo treatment with genotoxic agents.
Environmental mutagenesis 1985;7(6):889-99.
1984: K L Steinmetz; Jon C Mirsalis
Induction of unscheduled DNA synthesis in primary cultures of rat pancreatic cells following in vivo and in vitro treatment with genotoxic agents.
Environmental mutagenesis 1984;6(3):321-30.
1982: Jon C Mirsalis; C K Tyson; Byron E Butterworth
Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair assay.
Environmental mutagenesis 1982;4(5):553-62.