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Tom Misteli
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
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Research Profile (preview)
Anatomy
Chemicals & Drugs
Living Beings
Procedures
Genes & Molecular Sequences
Physiology
Concepts & Ideas
Phenomena
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Network (preview)
13
Dundr, Miroslav
9
Scaffidi, Paola
7
Soutoglou, Evi
6
Phair, Robert
6
Parada, Luis
6
Gorski, Stanislaw
4
Bustin, Michael
4
McQueen, Philip
4
Meshorer, Eran
3
McNally, James
3
Mazumdar, Manjari
3
Mabon, Stephen
3
Roix, Jeffrey
3
Brown, David
3
Hager, Gordon
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Publications
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All Publications
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2009: Mott Bryan T; Tanega Cordelle; Shen Min; Maloney David J; Shinn Paul; Leister William; Marugan Juan J; Inglese James; Austin Christopher P; Misteli Tom; Auld Douglas S; Thomas Craig J
Evaluation of substituted 6-arylquinazolin-4-amines as potent and selective inhibitors of cdc2-like kinases (Clk).
Bioorganic & medicinal chemistry letters 2009;19(23):6700-5.
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2009: Misteli Tom
JCB meeting: Cell Biology of Disease.
The Journal of cell biology 2009;187(2):155-6.
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2009: Pegoraro Gianluca; Kubben Nard; Wickert Ute; Göhler Heike; Hoffmann Katrin; Misteli Tom
Ageing-related chromatin defects through loss of the NURD complex.
Nature cell biology 2009;11(10):1261-7.
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2009: Hager Gordon L; McNally James G; Misteli Tom
Transcription dynamics.
Molecular cell 2009;35(6):741-53.
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2009: Misteli Tom
Self-organization in the genome.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(17):6885-6.
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2009: Hill Emma; deCathelineau Aimee; Misteli Tom
New science - new ways to communicate it.
The Journal of cell biology 2009;185(2):183-4.
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2009: Mathas Stephan; Kreher Stephan; Meaburn Karen J; Jöhrens Korinna; Lamprecht Björn; Assaf Chalid; Sterry Wolfram; Kadin Marshall E; Daibata Masanori; Joos Stefan; Hummel Michael; Stein Harald; Janz Martin; Anagnostopoulos Ioannis; Schrock Evelin; Misteli Tom; Dörken Bernd
Gene deregulation and spatial genome reorganization near breakpoints prior to formation of translocations in anaplastic large cell lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(14):5831-6.
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2009: Misteli Tom; Soutoglou Evi
The emerging role of nuclear architecture in DNA repair and genome maintenance.
Nature reviews. Molecular cell biology 2009;10(4):243-54.
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2009: Misteli Tom
The changing world of modern cell biology.
The Journal of cell biology 2009;184(1):11-2.
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2009: Méjat Alexandre; Decostre Valérie; Li Juan; Renou Laure; Kesari Akanchha; Hantaï Daniel; Stewart Colin L; Xiao Xiao; Hoffman Eric; Bonne Gisèle; Misteli Tom
Lamin A/C-mediated neuromuscular junction defects in Emery-Dreifuss muscular dystrophy.
The Journal of cell biology 2009;184(1):31-44.
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2008: Misteli Tom
Cell biology: Nuclear order out of chaos.
Nature 2008;456(7220):333-4.
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2008: Takizawa Takumi; Meaburn Karen J; Misteli Tom
The meaning of gene positioning.
Cell 2008;135(1):9-13.
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2008: Soutoglou Evi; Misteli Tom
Activation of the cellular DNA damage response in the absence of DNA lesions.
Science (New York, N.Y.) 2008;320(5882):1507-10.
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2008: Gorski Stanislaw A; Snyder Sara K; John Sam; Grummt Ingrid; Misteli Tom
Modulation of RNA polymerase assembly dynamics in transcriptional regulation.
Molecular cell 2008;30(4):486-97.
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2008: Efroni Sol; Duttagupta Radharani; Cheng Jill; Dehghani Hesam; Hoeppner Daniel J; Dash Chandravanu; Bazett-Jones David P; Le Grice Stuart; McKay Ronald D G; Buetow Kenneth H; Gingeras Thomas R; Misteli Tom; Meshorer Eran
Global transcription in pluripotent embryonic stem cells.
Cell stem cell 2008;2(5):437-47.
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2008: Scaffidi Paola; Misteli Tom
Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing.
Nature cell biology 2008;10(4):452-9.
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2008: Ayala Youhna M; Misteli Tom; Baralle Francisco E
TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(10):3785-9.
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2008: Takizawa Takumi; Gudla Prabhakar R; Guo Liying; Lockett Stephan; Misteli Tom
Allele-specific nuclear positioning of the monoallelically expressed astrocyte marker GFAP.
Genes & development 2008;22(4):489-98.
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2008: Meaburn Karen J; Misteli Tom
Locus-specific and activity-independent gene repositioning during early tumorigenesis.
The Journal of cell biology 2008;180(1):39-50.
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2008: Misteli Tom
Physiological importance of RNA and protein mobility in the cell nucleus.
Histochemistry and cell biology 2008;129(1):5-11.
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2008: Soutoglou Evi; Misteli Tom
On the contribution of spatial genome organization to cancerous chromosome translocations.
Journal of the National Cancer Institute. Monographs 2008;(39):16-9.
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2007: Caceres Javier F; Misteli Tom
Division of labor: minor splicing in the cytoplasm.
Cell 2007;131(4):645-7.
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2007: Soutoglou Evi; Misteli Tom
Mobility and immobility of chromatin in transcription and genome stability.
Current opinion in genetics & development 2007;17(5):435-42.
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2007: Liu Qian; Pante Nelly; Misteli Tom; Elsagga Mohamed; Crisp Melissa; Hodzic Didier; Burke Brian; Roux Kyle J
Functional association of Sun1 with nuclear pore complexes.
The Journal of cell biology 2007;178(5):785-98.
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2007: Kruhlak Michael; Crouch Elizabeth E; Orlov Marika; Montaño Carolina; Gorski Stanislaw A; Nussenzweig André; Misteli Tom; Phair Robert D; Casellas Rafael
The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks.
Nature 2007;447(7145):730-4.
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2007: Soutoglou Evi; Dorn Jonas F; Sengupta Kundan; Jasin Maria; Nussenzweig Andre; Ried Thomas; Danuser Gaudenz; Misteli Tom
Positional stability of single double-strand breaks in mammalian cells.
Nature cell biology 2007;9(6):675-82.
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2007: Dernburg Abby F; Misteli Tom
Nuclear architecture--an island no more.
Developmental cell 2007;12(3):329-34.
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2007: Misteli Tom
Beyond the sequence: cellular organization of genome function.
Cell 2007;128(4):787-800.
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2007: Meaburn Karen J; Misteli Tom; Soutoglou Evi
Spatial genome organization in the formation of chromosomal translocations.
Seminars in cancer biology 2007;17(1):80-90.
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2007: Meaburn Karen J; Misteli Tom
Cell biology: chromosome territories.
Nature 2007;445(7126):379-781.
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2007: Trotman Lloyd C; Wang Xinjiang; Alimonti Andrea; Chen Zhenbang; Teruya-Feldstein Julie; Yang Haijuan; Pavletich Nikola P; Carver Brett S; Cordon-Cardo Carlos; Erdjument-Bromage Hediye; Tempst Paul; Chi Sung-Gil; Kim Hyo-Jong; Misteli Tom; Jiang Xuejun; Pandolfi Pier Paolo
Ubiquitination regulates PTEN nuclear import and tumor suppression.
Cell 2007;128(1):141-56.
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2006: Mazumdar Manjari; Lee Ji-Hyeon; Sengupta Kundan; Ried Thomas; Rane Sushil; Misteli Tom
Tumor formation via loss of a molecular motor protein.
Current biology : CB 2006;16(15):1559-64.
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2006: Dahl Kris Noel; Scaffidi Paola; Islam Mohammad F; Yodh Arjun G; Wilson Katherine L; Misteli Tom
Distinct structural and mechanical properties of the nuclear lamina in Hutchinson-Gilford progeria syndrome.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10271-6.
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2006: Stavreva Diana A; Kawasaki Miyuki; Dundr Miroslav; Koberna Karel; Müller Waltraud G; Tsujimura-Takahashi Teruko; Komatsu Wataru; Hayano Toshiya; Isobe Toshiaki; Raska Ivan; Misteli Tom; Takahashi Nobuhiro; McNally James G
Potential roles for ubiquitin and the proteasome during ribosome biogenesis.
Molecular and cellular biology 2006;26(13):5131-45.
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2006: Meshorer Eran; Misteli Tom
Chromatin in pluripotent embryonic stem cells and differentiation.
Nature reviews. Molecular cell biology 2006;7(7):540-6.
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2006: Gorski Stanislaw A; Dundr Miroslav; Misteli Tom
The road much traveled: trafficking in the cell nucleus.
Current opinion in cell biology 2006;18(3):284-90.
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2006: Scaffidi Paola; Misteli Tom
Lamin A-dependent nuclear defects in human aging.
Science (New York, N.Y.) 2006;312(5776):1059-63.
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2006: Scaffidi Paola; Misteli Tom
Good news in the nuclear envelope: loss of lamin A might be a gain.
The Journal of clinical investigation 2006;116(3):632-4.
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2006: Brown David T; Izard Tina; Misteli Tom
Mapping the interaction surface of linker histone H1(0) with the nucleosome of native chromatin in vivo.
Nature structural & molecular biology 2006;13(3):250-5.
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2006: Meshorer Eran; Yellajoshula Dhananjay; George Eric; Scambler Peter J; Brown David T; Misteli Tom
Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells.
Developmental cell 2006;10(1):105-16.
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2006: Williams Ruth R E; Azuara Véronique; Perry Pascale; Sauer Stephan; Dvorkina Maria; Jørgensen Helle; Roix Jeffery; McQueen Philip; Misteli Tom; Merkenschlager Matthias; Fisher Amanda G
Neural induction promotes large-scale chromatin reorganisation of the Mash1 locus.
Journal of cell science 2006;119(Pt 1):132-40.
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2005: Scaffidi Paola; Gordon Leslie; Misteli Tom
The cell nucleus and aging: tantalizing clues and hopeful promises.
PLoS biology 2005;3(11):e395.
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2005: Mabon Stephen A; Misteli Tom
Differential recruitment of pre-mRNA splicing factors to alternatively spliced transcripts in vivo.
PLoS biology 2005;3(11):e374.
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2005: Gorski Stanislaw; Misteli Tom
Systems biology in the cell nucleus.
Journal of cell science 2005;118(Pt 18):4083-92.
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2005: Meshorer Eran; Misteli Tom
Splicing misplaced.
Cell 2005;122(3):317-8.
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2005: McNairn Adrian J; Okuno Yukiko; Misteli Tom; Gilbert David M
Chinese hamster ORC subunits dynamically associate with chromatin throughout the cell-cycle.
Experimental cell research 2005;308(2):345-56.
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2005: Becker Matthias; Becker Antje; Miyara Faiçal; Han Zhiming; Kihara Maki; Brown David T; Hager Gordon L; Latham Keith; Adashi Eli Y; Misteli Tom
Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer.
Molecular biology of the cell 2005;16(8):3887-95.
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2005: Misteli Tom; Scaffidi Paola
Genome instability in progeria: when repair gets old.
Nature medicine 2005;11(7):718-9.
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2005: Mazumdar Manjari; Misteli Tom
Chromokinesins: multitalented players in mitosis.
Trends in cell biology 2005;15(7):349-55.
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2005: Jiao Wan; Lin Huei-Min; Timmons Jamie; Nagaich Akhilesh K; Ng Shu-Wing; Misteli Tom; Rane Sushil G
E2F-dependent repression of topoisomerase II regulates heterochromatin formation and apoptosis in cells with melanoma-prone mutation.
Cancer research 2005;65(10):4067-77.
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2005: Misteli Tom
Concepts in nuclear architecture.
BioEssays : news and reviews in molecular, cellular and developmental biology 2005;27(5):477-87.
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2005: Scaffidi Paola; Misteli Tom
Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome.
Nature medicine 2005;11(4):440-5.
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2005: Misteli Tom
Going in GTP cycles in the nucleolus.
The Journal of cell biology 2005;168(2):177-8.
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2005: Chen Danyang; Dundr Miroslav; Wang Chen; Leung Anthony; Lamond Angus; Misteli Tom; Huang Sui
Condensed mitotic chromatin is accessible to transcription factors and chromatin structural proteins.
The Journal of cell biology 2005;168(1):41-54.
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2005: Tanaka Mamoru; Kihara Maki; Hennebold Jon D; Eppig John J; Viveiros Maria M; Emery Benjamin R; Carrell Douglas T; Kirkman Nikki J; Meczekalski Blazej; Zhou Jian; Bondy Carolyn A; Becker Matthias; Schultz Richard M; Misteli Tom; De La Fuente Rabindranath; King Gretchen J; Adashi Eli Y
H1FOO is coupled to the initiation of oocytic growth.
Biology of reproduction 2005;72(1):135-42.
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2005: Oliver Brian; Misteli Tom
A non-random walk through the genome.
Genome biology 2005;6(4):214.
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2004: Vecerová Jaromíra; Koberna Karel; Malínsky Jan; Soutoglou Evi; Sullivan Teresa; Stewart Colin L; Raska Ivan; Misteli Tom
Formation of nuclear splicing factor compartments is independent of lamins A/C.
Molecular biology of the cell 2004;15(11):4904-10.
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2004: Misteli Tom
Spatial positioning; a new dimension in genome function.
Cell 2004;119(2):153-6.
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2004: Mazumdar Manjari; Sundareshan Suma; Misteli Tom
Human chromokinesin KIF4A functions in chromosome condensation and segregation.
The Journal of cell biology 2004;166(5):613-20.
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2004: Phair Robert D; Scaffidi Paola; Elbi Cem; Vecerová Jaromíra; Dey Anup; Ozato Keiko; Brown David T; Hager Gordon; Bustin Michael; Misteli Tom
Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins.
Molecular and cellular biology 2004;24(14):6393-402.
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2004: Catez Frédéric; Yang Huan; Tracey Kevin J; Reeves Raymond; Misteli Tom; Bustin Michael
Network of dynamic interactions between histone H1 and high-mobility-group proteins in chromatin.
Molecular and cellular biology 2004;24(10):4321-8.
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2004: Parada Luis A; Sotiriou Sotiria; Misteli Tom
Spatial genome organization.
Experimental cell research 2004;296(1):64-70.
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2004: Cheutin Thierry; Gorski Stanislaw A; May Karen M; Singh Prim B; Misteli Tom
In vivo dynamics of Swi6 in yeast: evidence for a stochastic model of heterochromatin.
Molecular and cellular biology 2004;24(8):3157-67.
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2004: Dundr Miroslav; Hebert Michael D; Karpova Tatiana S; Stanek David; Xu Hongzi; Shpargel Karl B; Meier U Thomas; Neugebauer Karla M; Matera A Gregory; Misteli Tom
In vivo kinetics of Cajal body components.
The Journal of cell biology 2004;164(6):831-42.
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2004: Misteli Tom
The flow of gene expression.
Nature structural & molecular biology 2004;11(3):202-5.
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2004: Nicot Christophe; Dundr Miroslav; Johnson Julie M; Fullen Jake R; Alonzo Norma; Fukumoto Risaku; Princler Gerald L; Derse David; Misteli Tom; Franchini Genoveffa
HTLV-1-encoded p30II is a post-transcriptional negative regulator of viral replication.
Nature medicine 2004;10(2):197-201.
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2004: Parada Luis A; McQueen Philip G; Misteli Tom
Tissue-specific spatial organization of genomes.
Genome biology 2004;5(7):R44.
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2004: Kim S H; McQueen P G; Lichtman M K; Shevach E M; Parada L A; Misteli T
Spatial genome organization during T-cell differentiation.
Cytogenetic and genome research 2004;105(2-4):292-301.
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2004: Phair Robert D; Gorski Stanislaw A; Misteli Tom
Measurement of dynamic protein binding to chromatin in vivo, using photobleaching microscopy.
Methods in enzymology 2004;375():393-414.
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2003: Parada Luis A; Roix Jeffrey J; Misteli Tom
An uncertainty principle in chromosome positioning.
Trends in cell biology 2003;13(8):393-6.
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2003: Dey Anup; Chitsaz Farideh; Abbasi Asim; Misteli Tom; Ozato Keiko
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(15):8758-63.
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2003: Roix Jeffrey J; McQueen Philip G; Munson Peter J; Parada Luis A; Misteli Tom
Spatial proximity of translocation-prone gene loci in human lymphomas.
Nature genetics 2003;34(3):287-91.
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2003: Dundr Miroslav; Misteli Tom
Measuring dynamics of nuclear proteins by photobleaching.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2003;Chapter 13():Unit 13.5.
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2003: Mellman Ira; Misteli Tom
Computational cell biology.
The Journal of cell biology 2003;161(3):463-4.
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2003: Misteli Tom
A nucleolar disappearing act in somatic cloning.
Nature cell biology 2003;5(3):183-4.
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2003: Cheutin Thierry; McNairn Adrian J; Jenuwein Thomas; Gilbert David M; Singh Prim B; Misteli Tom
Maintenance of stable heterochromatin domains by dynamic HP1 binding.
Science (New York, N.Y.) 2003;299(5607):721-5.
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2003: Misteli Tom
In vivo imaging.
Methods (San Diego, Calif.) 2003;29(1):1-2.
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2002: Dundr Miroslav; Hoffmann-Rohrer Urs; Hu Qiyue; Grummt Ingrid; Rothblum Lawrence I; Phair Robert D; Misteli Tom
A kinetic framework for a mammalian RNA polymerase in vivo.
Science (New York, N.Y.) 2002;298(5598):1623-6.
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2002: Dundr Miroslav; McNally James G; Cohen Jean; Misteli Tom
Quantitation of GFP-fusion proteins in single living cells.
Journal of structural biology 2002;140(1-3):92-9.
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2002: Parada Luis A; McQueen Philip G; Munson Peter J; Misteli Tom
Conservation of relative chromosome positioning in normal and cancer cells.
Current biology : CB 2002;12(19):1692-7.
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2002: Parada Luis; Misteli Tom
Chromosome positioning in the interphase nucleus.
Trends in cell biology 2002;12(9):425-32.
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2002: Roix Jeffrey; Misteli Tom
Genomes, proteomes, and dynamic networks in the cell nucleus.
Histochemistry and cell biology 2002;118(2):105-16.
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2002: Catez Frédéric; Brown David T; Misteli Tom; Bustin Michael
Competition between histone H1 and HMGN proteins for chromatin binding sites.
EMBO reports 2002;3(8):760-6.
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2002: Scaffidi Paola; Misteli Tom; Bianchi Marco E
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation.
Nature 2002;418(6894):191-5.
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2002: Cavanaugh Alice H; Hirschler-Laszkiewicz Iwona; Hu Qiyue; Dundr Miroslav; Smink Tom; Misteli Tom; Rothblum Lawrence I
Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis.
The Journal of biological chemistry 2002;277(30):27423-32.
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2002: Elbi Cem; Misteli Tom; Hager Gordon L
Recruitment of dioxin receptor to active transcription sites.
Molecular biology of the cell 2002;13(6):2001-15.
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2002: Intine Robert V; Dundr Miroslav; Misteli Tom; Maraia Richard J
Aberrant nuclear trafficking of La protein leads to disordered processing of associated precursor tRNAs.
Molecular cell 2002;9(5):1113-23.
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2002: Horowitz David S; Lee Edward J; Mabon Stephen A; Misteli Tom
A cyclophilin functions in pre-mRNA splicing.
The EMBO journal 2002;21(3):470-80.
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2002: Dundr Miroslav; Misteli Tom
Nucleolomics: an inventory of the nucleolus.
Molecular cell 2002;9(1):5-7.
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2001: Phair R D; Misteli T
Kinetic modelling approaches to in vivo imaging.
Nature reviews. Molecular cell biology 2001;2(12):898-907.
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2001: Kalbfuss B; Mabon S A; Misteli T
Correction of alternative splicing of tau in frontotemporal dementia and parkinsonism linked to chromosome 17.
The Journal of biological chemistry 2001;276(46):42986-93.
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2001: Misteli T
The concept of self-organization in cellular architecture.
The Journal of cell biology 2001;155(2):181-5.
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2001: Prymakowska-Bosak M; Misteli T; Herrera J E; Shirakawa H; Birger Y; Garfield S; Bustin M
Mitotic phosphorylation prevents the binding of HMGN proteins to chromatin.
Molecular and cellular biology 2001;21(15):5169-78.
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2001: Dundr M; Misteli T
Functional architecture in the cell nucleus.
The Biochemical journal 2001;356(Pt 2):297-310.
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2001: Misteli T
Protein dynamics: implications for nuclear architecture and gene expression.
Science (New York, N.Y.) 2001;291(5505):843-7.
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2000: Misteli T; Gunjan A; Hock R; Bustin M; Brown D T
Dynamic binding of histone H1 to chromatin in living cells.
Nature 2000;408(6814):877-81.
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2000: Dundr M; Misteli T; Olson M O
The dynamics of postmitotic reassembly of the nucleolus.
The Journal of cell biology 2000;150(3):433-46.
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2000: Misteli T
Cell biology of transcription and pre-mRNA splicing: nuclear architecture meets nuclear function.
Journal of cell science 2000;113 ( Pt 11)():1841-9.
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2000: Phair R D; Misteli T
High mobility of proteins in the mammalian cell nucleus.
Nature 2000;404(6778):604-9.
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1999: Misteli T; Spector D L
RNA polymerase II targets pre-mRNA splicing factors to transcription sites in vivo.
Molecular cell 1999;3(6):697-705.
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1999: Misteli T
RNA splicing: What has phosphorylation got to do with it?
Current biology : CB 1999;9(6):R198-200.
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1997: Misteli T; Spector D L
Applications of the green fluorescent protein in cell biology and biotechnology.
Nature biotechnology 1997;15(10):961-4.
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1997: Misteli T; Spector D L
Protein phosphorylation and the nuclear organization of pre-mRNA splicing.
Trends in cell biology 1997;7(4):135-8.
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1996: Misteli T; Spector D L
Serine/threonine phosphatase 1 modulates the subnuclear distribution of pre-mRNA splicing factors.
Molecular biology of the cell 1996;7(10):1559-72.
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1996: Misteli T
Molecular mechanisms in the disassembly and reassembly of the mammalian Golgi apparatus during M-phase.
FEBS letters 1996;389(1):66-9.
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1996: Misteli T
The mammalian Golgi apparatus during M-phase.
Progress in cell cycle research 1996;2():267-77.
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