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Beverly Mitchell

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Daniel A Pollyea; James Zehnder; Bing Zhang; Beverly S Mitchell; Omar Abdel-Wahab; Caroline Berube; Steve Coutre; Leonel Gallegos; Jason R Gotlib; Peter Greenberg; Ross Levine; Michaela Liedtke; Bruno C Medeiros
Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia.
Mohammad Namavari; Shahriar S Yaghoubi; Ya-Fang Chang; Brenda Kusler; Beverly S Mitchell; Sanjiv Sam Gambhir
Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.
Daniel A Pollyea; Aparna Raval; Ash A Alizadeh; Jason R Gotlib; Brenda Kusler; Beverly S Mitchell
Impact of TET2 mutations on mRNA expression and clinical outcomes in MDS patients treated with DNA methyltransferase inhibitors.

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2013: Daniel A Pollyea; James Zehnder; Bing Zhang; Beverly S Mitchell; Omar Abdel-Wahab; Caroline Berube; Steve Coutre; Leonel Gallegos; Jason R Gotlib; Peter Greenberg; Ross Levine; Michaela Liedtke; Bruno C Medeiros
Sequential azacitidine plus lenalidomide combination for elderly patients with untreated acute myeloid leukemia.
Haematologica 2013;98(4):591-6.
2011: Mohammad Namavari; Shahriar S Yaghoubi; Ya-Fang Chang; Brenda Kusler; Beverly S Mitchell; Sanjiv Sam Gambhir
Synthesis of 2'-deoxy-2'-[18F]fluoro-9-β-D-arabinofuranosylguanine: a novel agent for imaging T-cell activation with PET.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2011;13(5):812-8.
2011: Daniel A Pollyea; Aparna Raval; Ash A Alizadeh; Jason R Gotlib; Brenda Kusler; Beverly S Mitchell
Impact of TET2 mutations on mRNA expression and clinical outcomes in MDS patients treated with DNA methyltransferase inhibitors.
Hematological oncology 2011;29(3):157-60.
2009: Min Huang; Koji Itahana; Yanping Zhang; Beverly S Mitchell
Depletion of guanine nucleotides leads to the Mdm2-dependent proteasomal degradation of nucleostemin.
Cancer research 2009;69(7):3004-12.
2008: Min Huang; Yanhong Wang; Jing-Jin Gu; Jing Yang; Karen Noel; Beverly S Mitchell; Vern L Schramm; Lee M Graves
Determinants of sensitivity of human T-cell leukemia CCRF-CEM cells to immucillin-H.
Leukemia research 2008;32(8):1268-78.
2008: Min Huang; Beverly S Mitchell
Guanine nucleotide depletion mediates translocation of nucleolar proteins, including RNA helicase A (DHX-9).
Nucleosides, nucleotides & nucleic acids 2008;27(6):704-11.
2008: Rafal Sadej; Kunihiro Inai; Zenon Rajfur; Anna Ostapkowicz; Jon Kohler; Andrzej C Skladanowski; Beverly S Mitchell; Jozef Spychala
Tenascin C interacts with ecto-5'-nucleotidase (eN) and regulates adenosine generation in cancer cells.
Biochimica et biophysica acta 2008;1782(1):35-40.
2008: Min Huang; Yanshan Ji; Koji Itahana; Yanping Zhang; Beverly S Mitchell
Guanine nucleotide depletion inhibits pre-ribosomal RNA synthesis and causes nucleolar disruption.
Leukemia research 2008;32(1):131-41.
2007: Daniel J DeAngelo; Daohai Yu; Jeffrey L Johnson; Steven E Coutre; Richard M Stone; Alison T Stopeck; Jon P Gockerman; Beverly S Mitchell; Frederick R Appelbaum; Richard A Larson
Nelarabine induces complete remissions in adults with relapsed or refractory T-lineage acute lymphoblastic leukemia or lymphoblastic lymphoma: Cancer and Leukemia Group B study 19801.
Blood 2007;109(12):5136-42.
2006: Mike Douvas; Karen N Hogan; YanShan Ji; David Hollenback; Lynn Bonham; Jack W Singer; Beverly S Mitchell
Effect of lysophosphatidic acid acyltransferase-beta inhibition in acute leukemia.
Leukemia research 2006;30(8):1027-36.
2006: YanShan Ji; Jing-Jin Gu; Alexander M Makhov; Jack D Griffith; Beverly S Mitchell
Regulation of the interaction of inosine monophosphate dehydrogenase with mycophenolic Acid by GTP.
The Journal of biological chemistry 2006;281(1):206-12.
2005: Sally Anne Hunsucker; Beverly S Mitchell; Jozef Spychala
The 5'-nucleotidases as regulators of nucleotide and drug metabolism.
Pharmacology & therapeutics 2005;107(1):1-30.
2005: Joanne Kurtzberg; T J Ernst; Michael J Keating; Varsha Gandhi; JP Hodge; David Kisor; Joanne J Lager; C Stephens; J Levin; T Krenitsky; GB Elion; Beverly S Mitchell
Phase I study of 506U78 administered on a consecutive 5-day schedule in children and adults with refractory hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(15):3396-403.
2005: Robert Z Orlowski; Peter M Voorhees; Reynaldo A Garcia; Melissa D Hall; Fred J Kudrik; Tammy Allred; Anandhi R Johri; Paul E Jones; Anastasia Ivanova; Hendrik W van Deventer; Don A Gabriel; Thomas C Shea; Beverly S Mitchell; Julian Adams; Dixie Esseltine; Elizabeth Trehu; Marie Green; Mary Jo Lehman; Susan Natoli; Jason M Collins; Celeste Lindley; Elizabeth Dees
Phase 1 trial of the proteasome inhibitor bortezomib and pegylated liposomal doxorubicin in patients with advanced hematologic malignancies.
Blood 2005;105(8):3058-65.
2005: Jing-Jin Gu; Lalaine Santiago; Beverly S Mitchell
Synergy between imatinib and mycophenolic acid in inducing apoptosis in cell lines expressing Bcr-Abl.
Blood 2005;105(8):3270-7.
2005: Hyman Muss; Jamie H Von Roenn; Lloyd Earl Damon; Lisa De Angelis; Lawrence E Flaherty; Paul M Harari; Karen Kelly; Michael P Kosty; Matthew J Loscalzo; Robert Mennel; Beverly S Mitchell; Joanne E Mortimer; Franco Muggia; Edith A Perez; Peter W T Pisters; Leonard B Saltz; Lidia Schapira; Joseph A Sparano
ACCO: ASCO core curriculum outline.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(9):2049-77.
2004: Karim Malek; Michael S Boosalis; Kristin Waraska; Beverly S Mitchell; Daniel G Wright
Effects of the IMP-dehydrogenase inhibitor, Tiazofurin, in bcr-abl positive acute myelogenous leukemia. Part I. In vivo studies.
Leukemia research 2004;28(11):1125-36.
2004: Min Huang; Yanhong Wang; Beverly S Mitchell; Lee M Graves
Regulation of equilibrative nucleoside uptake by protein kinase inhibitors.
Nucleosides, nucleotides & nucleic acids 2004;23(8-9):1445-50.
2004: Aileen Aherne; Avril Kennan; Paul F Kenna; Niamh McNally; David Lloyd; Ian L Alberts; Anna-Sophia Kiang; Marian Humphries; Carmen Ayuso; Paul C Engel; Jing-Jin Gu; Beverly S Mitchell; G Jane Farrar; Peter Humphries
On the molecular pathology of neurodegeneration in IMPDH1-based retinitis pigmentosa.
Human molecular genetics 2004;13(6):641-50.
2004: Jozef Spychala; Eduardo R Lazarowski; Anna Ostapkowicz; Lanier H Ayscue; Aiwen Jin; Beverly S Mitchell
Role of estrogen receptor in the regulation of ecto-5'-nucleotidase and adenosine in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(2):708-17.
2003: Kiran N Mahajan; Beverly S Mitchell
Role of human Pso4 in mammalian DNA repair and association with terminal deoxynucleotidyl transferase.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):10746-51.
2003: Jing-Jin Gu; Amy K Tolin; Jugnu Jain; Hai Huang; Lalaine Santiago; Beverly S Mitchell
Targeted disruption of the inosine 5'-monophosphate dehydrogenase type I gene in mice.
Molecular and cellular biology 2003;23(18):6702-12.
2003: Beverly S Mitchell
The proteasome--an emerging therapeutic target in cancer.
The New England journal of medicine 2003;348(26):2597-8.
2003: Jing-Jin Gu; Karen Gathy; Lalaine Santiago; Eric Chen; Min Huang; Lee M Graves; Beverly S Mitchell
Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion.
Blood 2003;101(12):4958-65.
2003: Min Huang; Yanhong Wang; Susan B Cogut; Beverly S Mitchell; Lee M Graves
Inhibition of nucleoside transport by protein kinase inhibitors.
The Journal of pharmacology and experimental therapeutics 2003;304(2):753-60.
2002: Robert Z Orlowski; Thomas E Stinchcombe; Beverly S Mitchell; Thomas C Shea; Albert S Baldwin; Stephanie Stahl; Julian Adams; Dixie Esseltine; Peter J Elliott; Christine S Pien; Roberto Guerciolini; Jessica K Anderson; Natalie D Depcik-Smith; Rita Bhagat; Mary Jo Lehman; steven novick; Owen A O'Connor; Steven L Soignet
Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(22):4420-7.
2002: Hendrik W van Deventer; Melissa D Hall; Robert Z Orlowski; Beverly S Mitchell; Lee Berkowitz; Catherine Hogan; Dunphy Cherie; Julie Koehler; Thomas C Shea
Clinical course of thrombocytopenia in patients treated with imatinib mesylate for accelerated phase chronic myelogenous leukemia.
American journal of hematology 2002;71(3):184-90.
2002: Garth H Rauscher; Dale P Sandler; Charles Poole; James Pankow; Beverly S Mitchell; Clara D Bloomfield; Andrew F Olshan
Family history of cancer and incidence of acute leukemia in adults.
American journal of epidemiology 2002;156(6):517-26.
2002: Min Huang; Yanhong Wang; Matthew Collins; Beverly S Mitchell; Lee M Graves
A77 1726 induces differentiation of human myeloid leukemia K562 cells by depletion of intracellular CTP pools.
Molecular pharmacology 2002;62(3):463-72.
2002: Min Huang; Yanhong Wang; Matthew Collins; Jing-Jin Gu; Beverly S Mitchell; Lee M Graves
Inhibition of nucleoside transport by p38 MAPK inhibitors.
The Journal of biological chemistry 2002;277(32):28364-7.
2002: Jozef Spychala; Beverly S Mitchell
Cyclosporin A and FK506 decrease adenosine kinase activity and adenosine uptake in T-lymphocytes.
The Journal of laboratory and clinical medicine 2002;140(2):84-91.
2002: Kiran N Mahajan; Stephanie A Nick McElhinny; Beverly S Mitchell; Dale A Ramsden
Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair.
Molecular and cellular biology 2002;22(14):5194-202.
2002: Carlos O Rodriguez; Beverly S Mitchell; Mary Ayres; Staffan Eriksson; Varsha Gandhi
Arabinosylguanine is phosphorylated by both cytoplasmic deoxycytidine kinase and mitochondrial deoxyguanosine kinase.
Cancer research 2002;62(11):3100-5.
2001: A. William Blackstock; H Lightfoot; L Douglas Case; Joel E Tepper; Suresh K Mukherji; Beverly S Mitchell; S G Swarts; Suzanne M Hess
Tumor uptake and elimination of 2',2'-difluoro-2'-deoxycytidine (gemcitabine) after deoxycytidine kinase gene transfer: correlation with in vivo tumor response.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(10):3263-8.
2001: S A Hunsucker; Jozef Spychala; Beverly S Mitchell
Human cytosolic 5'-nucleotidase I: characterization and role in nucleoside analog resistance.
The Journal of biological chemistry 2001;276(13):10498-504.
2000: Jing-Jin Gu; S Stegmann; Karen Gathy; R Murray; J Laliberte; Lanier H Ayscue; Beverly S Mitchell
Inhibition of T lymphocyte activation in mice heterozygous for loss of the IMPDH II gene.
The Journal of clinical investigation 2000;106(4):599-606.
2000: David Kisor; William Plunkett; Joanne Kurtzberg; Beverly S Mitchell; JP Hodge; T Ernst; Michael J Keating; Varsha Gandhi
Pharmacokinetics of nelarabine and 9-beta-D-arabinofuranosyl guanine in pediatric and adult patients during a phase I study of nelarabine for the treatment of refractory hematologic malignancies.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(5):995-1003.
1999: Kiran N Mahajan; L Gangi-Peterson; D H Sorscher; J Wang; Karen Gathy; Nupam P Mahajan; W H Reeves; Beverly S Mitchell
Association of terminal deoxynucleotidyl transferase with Ku.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(24):13926-31.
1999: Jozef Spychala; A G Zimmermann; Beverly S Mitchell
Tissue-specific regulation of the ecto-5'-nucleotidase promoter. Role of the camp response element site in mediating repression by the upstream regulatory region.
The Journal of biological chemistry 1999;274(32):22705-12.
1999: L Gangi-Peterson; D H Sorscher; J W Reynolds; Thomas B Kepler; Beverly S Mitchell
Nucleotide pool imbalance and adenosine deaminase deficiency induce alterations of N-region insertions during V(D)J recombination.
The Journal of clinical investigation 1999;103(6):833-41.
1999: Jozef Spychala; V Chen; J Oka; Beverly S Mitchell
ATP and phosphate reciprocally affect subunit association of human recombinant High Km 5'-nucleotidase. Role for the C-terminal polyglutamic acid tract in subunit association and catalytic activity.
European journal of biochemistry / FEBS 1999;259(3):851-8.
1998: Varsha Gandhi; William Plunkett; Carlos O Rodriguez; B J Nowak; Min Du; Mary Ayres; David Kisor; Beverly S Mitchell; Joanne Kurtzberg; Michael J Keating
Compound GW506U78 in refractory hematologic malignancies: relationship between cellular pharmacokinetics and clinical response.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(11):3607-15.
1998: J Laliberté; A Yee; Yue Xiong; Beverly S Mitchell
Effects of guanine nucleotide depletion on cell cycle progression in human T lymphocytes.
Blood 1998;91(8):2896-904.
1998: A G Zimmermann; Jing-Jin Gu; J Laliberté; Beverly S Mitchell
Inosine-5'-monophosphate dehydrogenase: regulation of expression and role in cellular proliferation and T lymphocyte activation.
Progress in nucleic acid research and molecular biology 1998;61():181-209.
1997: A G Zimmermann; K L Wright; Jenny P-Y Ting; Beverly S Mitchell
Regulation of inosine-5'-monophosphate dehydrogenase type II gene expression in human T cells. Role for a novel 5' palindromic octamer sequence.
The Journal of biological chemistry 1997;272(36):22913-23.
1997: S H Kang; A K Sinhababu; J G Cory; Beverly S Mitchell; Dhiren R Thakker; Moo Je Cho
Cellular delivery of nucleoside diphosphates: a prodrug approach.
Pharmaceutical research 1997;14(6):706-12.
1997: Jozef Spychala; Beverly S Mitchell; J Barankiewicz
Adenosine metabolism during phorbol myristate acetate-mediated induction of HL-60 cell differentiation: changes in expression pattern of adenosine kinase, adenosine deaminase, and 5'-nucleotidase.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4947-52.
1997: Jing-Jin Gu; Jozef Spychala; Beverly S Mitchell
Regulation of the human inosine monophosphate dehydrogenase type I gene. Utilization of alternative promoters.
The Journal of biological chemistry 1997;272(7):4458-66.
1996: Beverly S Mitchell; Mark E Brecher
A 73-year-old woman with anemia and thrombocytopenia.
Journal of the American Geriatrics Society 1996;44(6):723-6.
1996: D M Hapke; A P Stegmann; Beverly S Mitchell
Retroviral transfer of deoxycytidine kinase into tumor cell lines enhances nucleoside toxicity.
Cancer research 1996;56(10):2343-7.
1996: Yoshinobu Manome; Patrick Y Wen; Y Dong; T Tanaka; Beverly S Mitchell; Donald Kufe; H A Fine
Viral vector transduction of the human deoxycytidine kinase cDNA sensitizes glioma cells to the cytotoxic effects of cytosine arabinoside in vitro and in vivo.
Nature medicine 1996;2(5):567-73.
1996: Jozef Spychala; Nabanita S Datta; K Takabayashi; M Datta; I H Fox; T Gribbin; Beverly S Mitchell
Cloning of human adenosine kinase cDNA: sequence similarity to microbial ribokinases and fructokinases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(3):1232-7.
1996: A Zimmermann; Jing-Jin Gu; Jozef Spychala; Beverly S Mitchell
Inosine monophosphate dehydrogenase expression: transcriptional regulation of the type I and type II genes.
Advances in enzyme regulation 1996;36():75-84.
1995: P W Hager; F R Collart; E Huberman; Beverly S Mitchell
Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.
Biochemical pharmacology 1995;49(9):1323-9.
1995: Carlo V Catapano; J S Dayton; Beverly S Mitchell; Daniel J Fernandes
GTP depletion induced by IMP dehydrogenase inhibitors blocks RNA-primed DNA synthesis.
Molecular pharmacology 1995;47(5):948-55.
1995: E H Chen; E E Johnson; S M Vetter; Beverly S Mitchell
Characterization of the deoxycytidine kinase promoter in human lymphoblast cell lines.
The Journal of clinical investigation 1995;95(4):1660-8.
1995: A G Zimmermann; Jozef Spychala; Beverly S Mitchell
Characterization of the human inosine-5'-monophosphate dehydrogenase type II gene.
The Journal of biological chemistry 1995;270(12):6808-14.
1994: Jing-Jin Gu; Kathleen Kaiser-Rogers; Kathleen W Rao; Beverly S Mitchell
Assignment of the human type I IMP dehydrogenase gene (IMPDH1) to chromosome 7q31.3-q32).
Genomics 1994;24(1):179-81.
1994: E H Chen; Beverly S Mitchell
Hereditary overexpression of adenosine deaminase in erythrocytes: studies in erythroid cell lines and transgenic mice.
Blood 1994;84(7):2346-53.
1994: Michael Flasshove; D Strumberg; L Ayscue; Beverly S Mitchell; C Tirier; W Heit; Siegfried Seeber; Jochen Schütte
Structural analysis of the deoxycytidine kinase gene in patients with acute myeloid leukemia and resistance to cytosine arabinoside.
Leukemia 1994;8(5):780-5.
1994: J S Dayton; T Lindsten; Craig Thompson; Beverly S Mitchell
Effects of human T lymphocyte activation on inosine monophosphate dehydrogenase expression.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(3):984-91.
1994: Jozef Spychala; Beverly S Mitchell
Regulation of low Km (ecto-) 5'-nucleotidase gene expression in leukemic cells.
Advances in experimental medicine and biology 1994;370():683-7.
1993: E H Chen; A P Tartaglia; Beverly S Mitchell
Hereditary overexpression of adenosine deaminase in erythrocytes: evidence for a cis-acting mutation.
American journal of human genetics 1993;53(4):889-93.
1993: J S Dayton; Beverly S Mitchell
Type I inosine monophosphate dehydrogenase: evidence for a single functional gene in mammalian species.
Biochemical and biophysical research communications 1993;195(2):897-901.
1993: Beverly S Mitchell; J S Dayton; Laurence A Turka; Craig Thompson
IMP dehydrogenase inhibitors as immunomodulators.
Annals of the New York Academy of Sciences 1993;685():217-24.
1993: J J Song; S Walker; E Chen; E E Johnson; Jozef Spychala; T Gribbin; Beverly S Mitchell
Genomic structure and chromosomal localization of the human deoxycytidine kinase gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(2):431-4.
1993: Beverly S Mitchell; J J Song; E E Johnson; E Chen; J S Dayton
Regulation of human deoxycytidine kinase expression.
Advances in enzyme regulation 1993;33():61-8.
1992: J K Owens; Donna S Shewach; Buddy Ullman; Beverly S Mitchell
Resistance to 1-beta-D-arabinofuranosylcytosine in human T-lymphoblasts mediated by mutations within the deoxycytidine kinase gene.
Cancer research 1992;52(9):2389-93.
1992: J S Dayton; Laurence A Turka; Craig Thompson; Beverly S Mitchell
Comparison of the effects of mizoribine with those of azathioprine, 6-mercaptopurine, and mycophenolic acid on T lymphocyte proliferation and purine ribonucleotide metabolism.
Molecular pharmacology 1992;41(4):671-6.
1991: Laurence A Turka; J Dayton; G Sinclair; Craig Thompson; Beverly S Mitchell
Guanine ribonucleotide depletion inhibits T cell activation. Mechanism of action of the immunosuppressive drug mizoribine.
The Journal of clinical investigation 1991;87(3):940-8.
1991: E G Chottiner; Donna S Shewach; Nabanita S Datta; E Ashcraft; D Gribbin; David Ginsburg; I H Fox; Beverly S Mitchell
Cloning and expression of human deoxycytidine kinase cDNA.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1531-5.
1991: J S Dayton; Laurence A Turka; Craig Thompson; Beverly S Mitchell
Guanine ribonucleotide depletion inhibits T cell activation.
Advances in experimental medicine and biology 1991;309B():293-6.
1990: C A Hanson; T E Gribbin; Bertram Schnitzer; J A Schlegelmilch; Beverly S Mitchell; Lloyd M Stoolman
CD11c (LEU-M5) expression characterizes a B-cell chronic lymphoproliferative disorder with features of both chronic lymphocytic leukemia and hairy cell leukemia.
Blood 1990;76(11):2360-7.
1990: S S Mattano; T D Palella; Beverly S Mitchell
Mutations induced at the hypoxanthine-guanine phosphoribosyltransferase locus of human T-lymphoblasts by perturbations of purine deoxyribonucleoside triphosphate pools.
Cancer research 1990;50(15):4566-71.
1989: Donna S Shewach; Beverly S Mitchell
Differential metabolism of 9-beta-D-arabinofuranosylguanine in human leukemic cells.
Cancer research 1989;49(23):6498-502.
1989: T E Gribbin; C K Stein; J S Harrison; Thomas W Glover; C A Hanson; JJ Wasmuth; R L Cody; Beverly S Mitchell
Association of a mature B cell leukemia with a 4p+ chromosomal abnormality: derivation and characterization of a cell line.
Leukemia 1989;3(9):643-7.
1989: E G Chottiner; David Ginsburg; A P Tartaglia; Beverly S Mitchell
Erythrocyte adenosine deaminase overproduction in hereditary hemolytic anemia.
Blood 1989;74(1):448-53.
1989: Nabanita S Datta; Donna S Shewach; Beverly S Mitchell; I H Fox
Kinetic properties and inhibition of human T lymphoblast deoxycytidine kinase.
The Journal of biological chemistry 1989;264(16):9359-64.
1989: T Gribbin; E Chottiner; David Ginsburg; Beverly S Mitchell
Identification of an Apa I polymorphism within the human adenosine deaminase (ADA) gene.
Nucleic acids research 1989;17(9):3626.
1989: Nabanita S Datta; Donna S Shewach; mary hurley; Beverly S Mitchell; I H Fox
Human T-lymphoblast deoxycytidine kinase: purification and properties.
Biochemistry 1989;28(1):114-23.
1989: E G Chottiner; David Ginsburg; Beverly S Mitchell
Autosomal dominant hemolytic anemia and adenosine deaminase overproduction.
Advances in experimental medicine and biology 1989;253A():493-7.
1989: E G Chottiner; T E Gribbin; David Ginsburg; Beverly S Mitchell
Erythrocyte-specific overproduction of adenosine deaminase: molecular genetic studies.
Progress in clinical and biological research 1989;319():55-64; discussion 65-8.
1989: Nabanita S Datta; Donna S Shewach; M C Hurley; Beverly S Mitchell; I H Fox
Properties of highly purified human T lymphoblast (MOLT-4) deoxycytidine kinase.
Advances in experimental medicine and biology 1989;253B():87-92.
1987: T E Gan; P E Dadonna; Beverly S Mitchell
Genetic expression of adenosine deaminase in human lymphoid malignancies.
Blood 1987;69(5):1376-80.
1987: robert simpson; T Hsu; D A Begley; Beverly S Mitchell; B N Alizadeh
Transcriptional regulation of the c-myc protooncogene by 1,25-dihydroxyvitamin D3 in HL-60 promyelocytic leukemia cells.
The Journal of biological chemistry 1987;262(9):4104-8.
1987: E G Chottiner; H J Cloft; A P Tartaglia; Beverly S Mitchell
Elevated adenosine deaminase activity and hereditary hemolytic anemia. Evidence for abnormal translational control of protein synthesis.
The Journal of clinical investigation 1987;79(3):1001-5.
1986: Donna S Shewach; Beverly S Mitchell
Characterization of arabinosylguanine resistance in a lymphoblastoid cell line.
Advances in experimental medicine and biology 1986;195 Pt B():605-9.
1985: Y Sidi; Beverly S Mitchell
Z-nucleotide accumulation in erythrocytes from Lesch-Nyhan patients.
The Journal of clinical investigation 1985;76(6):2416-9.
1985: Y Sidi; J L Hudson; Beverly S Mitchell
Effects of guanine ribonucleotide accumulation on the metabolism and cell cycle of human lymphoid cells.
Cancer research 1985;45(10):4940-5.
1985: Beverly S Mitchell; Y Sidi
Differential metabolism of guanine nucleosides by human lymphoid cell lines.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 1985;179(4):427-31.
1985: Y Sidi; N L Edwards; C Winkler; P Bunn; Beverly S Mitchell
Differential metabolism of deoxyribonucleosides by leukaemic T cells of immature and mature phenotype.
British journal of haematology 1985;61(1):125-34.
1985: Donna S Shewach; P E Daddona; E Ashcraft; Beverly S Mitchell
Metabolism and selective cytotoxicity of 9-beta-D-arabinofuranosylguanine in human lymphoblasts.
Cancer research 1985;45(3):1008-14.
1985: Beverly S Mitchell; Y Sidi; M Hershfield; C A Koller
Biochemical consequences of adenosine deaminase inhibition in vivo. Differential effects in acute and chronic T cell leukemia.
Annals of the New York Academy of Sciences 1985;451():129-37.
1984: Y Sidi; Beverly S Mitchell
2'-deoxyguanosine toxicity for B and mature T lymphoid cell lines is mediated by guanine ribonucleotide accumulation.
The Journal of clinical investigation 1984;74(5):1640-8.
1984: Beverly S Mitchell; N L Edwards
Purine metabolizing enzymes as predictors of lymphoblast sensitivity to deoxyadenosine.
The Journal of laboratory and clinical medicine 1984;104(3):414-24.
1984: N L Edwards; Beverly S Mitchell; I H Fox; J J Mond
Plasma membrane 5'-nucleotidase and other purine enzymes in murine lymphocytes.
Advances in experimental medicine and biology 1984;165 Pt B():129-32.
1983: P E Daddona; Beverly S Mitchell; H J Meuwissen; B L Davidson; J M Wilson; C A Koller
Adenosine deaminase deficiency with normal immune function. An acidic enzyme mutation.
The Journal of clinical investigation 1983;72(2):483-92.
1983: Beverly S Mitchell; N L Edwards; C A Koller
Deoxyribonucleoside triphosphate accumulation by leukemic cells.
Blood 1983;62(2):419-24.
1983: M S Hershfield; N M Kredich; C A Koller; Beverly S Mitchell; J Kurtzberg; T R Kinney; J M Falletta
S-adenosylhomocysteine catabolism and basis for acquired resistance during treatment of T-cell acute lymphoblastic leukemia with 2'-deoxycoformycin alone and in combination with 9-beta-D-arabinofuranosyladenine.
Cancer research 1983;43(7):3451-8.
1983: C A Koller; Beverly S Mitchell
Alterations in erythrocyte adenine nucleotide pools resulting from 2'-deoxycoformycin therapy.
Cancer research 1983;43(3):1409-14.
1981: I S Kazmers; Beverly S Mitchell; P E Dadonna; LL Wotring; Leroy B Townsend; W N Kelley
Inhibition of purine nucleoside phosphorylase by 8-aminoguanosine: selective toxicity for T lymphoblasts.
Science (New York, N.Y.) 1981;214(4525):1137-9.
1980: C A Koller; P L Stetson; L D Nichamin; Beverly S Mitchell
An assay of deoxyadenosine and adenosine in human plasma by HPLC.
Biochemical medicine 1980;24(2):179-84.
1980: M F Siaw; Beverly S Mitchell; C A Koller; M S Coleman; J J Hutton
ATP depletion as a consequence of adenosine deaminase inhibition in man.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):6157-61.
1980: Beverly S Mitchell; C A Koller; R Heyn
Inhibition of adenosine deaminase activity results in cytotoxicity to T lymphoblasts in vivo.
Blood 1980;56(3):556-9.
1980: Beverly S Mitchell; W N Kelley
Purinogenic immunodeficiency diseases: clinical features and molecular mechanisms.
Annals of internal medicine 1980;92(6):826-31.
1979: C A Koller; Beverly S Mitchell; M R Grever; E Mejias; L Malspeis; E N Metz
Treatment of acute lymphoblastic leukemia with 2'-deoxycoformycin: clinical and biochemical consequences of adenosine deaminase inhibition.
Cancer treatment reports 1979;63(11-12):1949-52.
1979: J M Wilson; Beverly S Mitchell; P E Daddona; W N Kelley
Purinogenic immunodeficiency diseases. Differential effects of deoxyadenosine and deoxyguanosine on DNA synthesis in human T lymphoblasts.
The Journal of clinical investigation 1979;64(5):1475-84.
1979: R L Wortmann; Beverly S Mitchell; N L Edwards; I H Fox
Biochemical basis for differential deoxyadenosine toxicity to T and B lymphoblasts: role for 5'-nucleotidase.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(5):2434-7.
1979: Beverly S Mitchell; C A Koller; W N Kelley
Treatment of acute lymphoblastic leukemia with the adenosine deaminase inhibitor 2'-deoxycoformycin.
Advances in experimental medicine and biology 1979;122B():347-50.
1979: J M Wilson; Beverly S Mitchell; W N Kelley
Molecular mechanism(s) of deoxyribonucleoside toxicity in T-lymphoblasts.
Advances in experimental medicine and biology 1979;122B():265-70.
1979: R L Wortmann; Beverly S Mitchell; N L Edwards; I H Fox
Possible role for 5'-nucleotidase in deoxyadenosine selective toxicity to cultured human lymphoblasts.
Advances in experimental medicine and biology 1979;122B():243-59.
1978: Beverly S Mitchell; E Mejias; P E Daddona; W N Kelley
Purinogenic immunodeficiency diseases: selective toxicity of deoxyribonucleosides for T cells.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(10):5011-4.