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Claire Mitchell

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Chemicals & Drugs

Anatomy

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Physiology

Intraocular Pressure

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TOP 3
J C Lim; Claire H Mitchell
Inflammation, pain, and pressure--purinergic signaling in oral tissues.
Sonia Guha; Alan M Laties; Jason C Lim; Ji Liu; Wennan Lu; Arthur Argall; Gabriel C Baltazar; Kathleen Boesze-Battaglia; Leigh-Anne Tu; Claire H Mitchell
Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Ji Liu; Wennan Lu; William W Reenstra; Ronald C Rubenstein; Gabriel C Baltazar; Erin E Coffey; Sonia Guha; Alan M Laties; Claire H Mitchell
Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.

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All Publications

2012: J C Lim; Claire H Mitchell
Inflammation, pain, and pressure--purinergic signaling in oral tissues.
Journal of dental research 2012;91(12):1103-9.
2012: Sonia Guha; Alan M Laties; Jason C Lim; Ji Liu; Wennan Lu; Arthur Argall; Gabriel C Baltazar; Kathleen Boesze-Battaglia; Leigh-Anne Tu; Claire H Mitchell
Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris.
Journal of neurochemistry 2012;122(4):823-33.
2012: Ji Liu; Wennan Lu; William W Reenstra; Ronald C Rubenstein; Gabriel C Baltazar; Erin E Coffey; Sonia Guha; Alan M Laties; Claire H Mitchell
Cystic fibrosis transmembrane conductance regulator contributes to reacidification of alkalinized lysosomes in RPE cells.
American journal of physiology. Cell physiology 2012;303(2):C160-9.
2012: Jingsheng Xia; Jonathan M Beckel; Alan M Laties; Jason C Lim; Wennan Lu; Edward J Macarak; Claire H Mitchell
Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors.
The Journal of physiology 2012;590(Pt 10):2285-304.
2012: Gabriel C Baltazar; Kathleen Boesze-Battaglia; Sonia Guha; Uday B Kompella; Alan M Laties; Jason Lim; Wennan Lu; Puneet Tyagi; Claire H Mitchell
Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells.
PloS one 2012;7(12):e49635.
2012: Ang Li; Claire H Mitchell; Kim Peterson-Yantorno; W Daniel Stamer; Chi Ting Leung; Mortimer M Civan
Mechanisms of ATP release by human trabecular meshwork cells, the enabling step in purinergic regulation of aqueous humor outflow.
Journal of cellular physiology 2012;227(1):172-82.
2011: Ang Li; Jian Ge; Alan M Laties; Xiulan Zhang; Danying Zheng; Claire H Mitchell
Sustained elevation of extracellular ATP in aqueous humor from humans with primary chronic angle-closure glaucoma.
Experimental eye research 2011;93(4):528-33.
2010: Ang Li; Chi Ting Leung; Kim Peterson-Yantorno; Claire H Mitchell; Mortimer M Civan
Pathways for ATP release by bovine ciliary epithelial cells, the initial step in purinergic regulation of aqueous humor inflow.
American journal of physiology. Cell physiology 2010;299(6):C1308-17.
2010: Ulrike Zeiger; Claire H Mitchell; Tejvir S Khurana
Superior calcium homeostasis of extraocular muscles.
Experimental eye research 2010;91(5):613-22.
2010: Huiling Hu; Wennan Lu; Mei Zhang; Xiulan Zhang; Arthur J Argall; Shaun Patel; Ga Eun Lee; Yong-Chul Kim; Kenneth Alan Jacobson; Alan M Laties; Claire H Mitchell
Stimulation of the P2X7 receptor kills rat retinal ganglion cells in vivo.
Experimental eye research 2010;91(3):425-32.
2010: Mei Zhang; Huiling Hu; Xiulan Zhang; Wennan Lu; Jason Lim; Thor Eysteinsson; Kenneth Alan Jacobson; Alan M Laties; Claire H Mitchell
The A3 adenosine receptor attenuates the calcium rise triggered by NMDA receptors in retinal ganglion cells.
Neurochemistry international 2010;56(1):35-41.
2009: Claire H Mitchell; Wennan Lu; Huiling Hu; Xiulan Zhang; David Reigada; Mei Zhang
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.
Purinergic signalling 2009;5(2):241-9.
2008: Claire H Mitchell; Wennan Lu; Huiling Hu; Xiulan Zhang; David Reigada; Mei Zhang
The P2X(7) receptor in retinal ganglion cells: A neuronal model of pressure-induced damage and protection by a shifting purinergic balance.
Purinergic signalling 2008;4(4):313-21.
2008: David Reigada; Wennan Lu; Mei Zhang; Claire H Mitchell
Elevated pressure triggers a physiological release of ATP from the retina: Possible role for pannexin hemichannels.
Neuroscience 2008;157(2):396-404.
2008: Claire H Mitchell; David Reigada
Purinergic signalling in the subretinal space: a role in the communication between the retina and the RPE.
Purinergic signalling 2008;4(2):101-7.
2008: Ji Liu; Wennan Lu; David Reigada; Jonathan Nguyen; Alan M Laties; Claire H Mitchell
Restoration of lysosomal pH in RPE cells from cultured human and ABCA4(-/-) mice: pharmacologic approaches and functional recovery.
Investigative ophthalmology & visual science 2008;49(2):772-80.
2007: Xiulan Zhang; Ang Li; Jian Ge; David Reigada; Alan M Laties; Claire H Mitchell
Acute increase of intraocular pressure releases ATP into the anterior chamber.
Experimental eye research 2007;85(5):637-43.
2007: Wennan Lu; David Reigada; Jean Sévigny; Claire H Mitchell
Stimulation of the P2Y1 receptor up-regulates nucleoside-triphosphate diphosphohydrolase-1 in human retinal pigment epithelial cells.
The Journal of pharmacology and experimental therapeutics 2007;323(1):157-64.
2007: Jingsheng Xia; David Reigada; Claire H Mitchell; Dejian Ren
CATSPER channel-mediated Ca2+ entry into mouse sperm triggers a tail-to-head propagation.
Biology of reproduction 2007;77(3):551-9.
2007: Sukhamay Lahiri; Claire H Mitchell; David Reigada; Arijit Roy; N S Cherniack
Purines, the carotid body and respiration.
Respiratory physiology & neurobiology 2007;157(1):123-9.
2006: David Reigada; Wennan Lu; Claire H Mitchell
Glutamate acts at NMDA receptors on fresh bovine and on cultured human retinal pigment epithelial cells to trigger release of ATP.
The Journal of physiology 2006;575(Pt 3):707-20.
2006: Xiulan Zhang; Mei Zhang; Alan M Laties; Claire H Mitchell
Balance of purines may determine life or death of retinal ganglion cells as A3 adenosine receptors prevent loss following P2X7 receptor stimulation.
Journal of neurochemistry 2006;98(2):566-75.
2006: Mei Zhang; Murat T Budak; Wennan Lu; Tejvir S Khurana; Xiulan Zhang; Alan M Laties; Claire H Mitchell
Identification of the A3 adenosine receptor in rat retinal ganglion cells.
Molecular vision 2006;12():937-48.
2005: Anand S Patel; David Reigada; Claire H Mitchell; Sandra R Bates; Susan S Margulies; Michael Koval
Paracrine stimulation of surfactant secretion by extracellular ATP in response to mechanical deformation.
American journal of physiology. Lung cellular and molecular physiology 2005;289(3):L489-96.
2005: David Reigada; Wennan Lu; Xiulan Zhang; Constantin Friedman; Klara Pendrak; Alice M McGlinn; Richard A Stone; Alan M Laties; Claire H Mitchell
Degradation of extracellular ATP by the retinal pigment epithelium.
American journal of physiology. Cell physiology 2005;289(3):C617-24.
2005: Xiulan Zhang; Mei Zhang; Alan M Laties; Claire H Mitchell
Stimulation of P2X7 receptors elevates Ca2+ and kills retinal ganglion cells.
Investigative ophthalmology & visual science 2005;46(6):2183-91.
2005: Mike Karl; Johannes C Fleischhauer; W Daniel Stamer; Kim Peterson-Yantorno; Claire H Mitchell; Richard A Stone; Mortimer M Civan
Differential P1-purinergic modulation of human Schlemm's canal inner-wall cells.
American journal of physiology. Cell physiology 2005;288(4):C784-94.
2005: Chi Wai Do; Wennan Lu; Claire H Mitchell; Mortimer M Civan
Inhibition of swelling-activated Cl- currents by functional anti-ClC-3 antibody in native bovine non-pigmented ciliary epithelial cells.
Investigative ophthalmology & visual science 2005;46(3):948-55.
2005: David Reigada; Claire H Mitchell
Release of ATP from retinal pigment epithelial cells involves both CFTR and vesicular transport.
American journal of physiology. Cell physiology 2005;288(1):C132-40.
2004: Chi Wai Do; Kim Peterson-Yantorno; Claire H Mitchell; Mortimer M Civan
cAMP-activated maxi-Cl(-) channels in native bovine pigmented ciliary epithelial cells.
American journal of physiology. Cell physiology 2004;287(4):C1003-11.
2003: Johannes C Fleischhauer; Claire H Mitchell; W Daniel Stamer; Mike Karl; Kim Peterson-Yantorno; Mortimer M Civan
Common actions of adenosine receptor agonists in modulating human trabecular meshwork cell transport.
The Journal of membrane biology 2003;193(2):121-36.
2003: Marcel Y Avila; Claire H Mitchell; Richard A Stone; Mortimer M Civan
Noninvasive assessment of aqueous humor turnover in the mouse eye.
Investigative ophthalmology & visual science 2003;44(2):722-7.
2002: Claire H Mitchell; Johannes C Fleischhauer; W Daniel Stamer; Kim Peterson-Yantorno; Mortimer M Civan
Human trabecular meshwork cell volume regulation.
American journal of physiology. Cell physiology 2002;283(1):C315-26.
2001: Johannes C Fleischhauer; Claire H Mitchell; Kim Peterson-Yantorno; Miguel Coca-Prados; Mortimer M Civan
PGE(2), Ca(2+), and cAMP mediate ATP activation of Cl(-) channels in pigmented ciliary epithelial cells.
American journal of physiology. Cell physiology 2001;281(5):C1614-23.
2001: Charles W McLaughlin; D Peart; RD Purves; DA Carré; Kim Peterson-Yantorno; Claire H Mitchell; Anthony D C Macknight; Mortimer M Civan
Timolol may inhibit aqueous humor secretion by cAMP-independent action on ciliary epithelial cells.
American journal of physiology. Cell physiology 2001;281(3):C865-75.
2001: Claire H Mitchell
Release of ATP by a human retinal pigment epithelial cell line: potential for autocrine stimulation through subretinal space.
The Journal of physiology 2001;534(Pt 1):193-202.
2000: DA Carré; Claire H Mitchell; Kim Peterson-Yantorno; Miguel Coca-Prados; Mortimer M Civan
Similarity of A(3)-adenosine and swelling-activated Cl(-) channels in nonpigmented ciliary epithelial cells.
American journal of physiology. Cell physiology 2000;279(2):C440-51.
2000: Claire H Mitchell; Kim Peterson-Yantorno; Miguel Coca-Prados; Mortimer M Civan
Tamoxifen and ATP synergistically activate Cl- release by cultured bovine pigmented ciliary epithelial cells.
The Journal of physiology 2000;525 Pt 1():183-93.
1999: Claire H Mitchell; Kim Peterson-Yantorno; DA Carré; Alice M McGlinn; Miguel Coca-Prados; Richard A Stone; Mortimer M Civan
A3 adenosine receptors regulate Cl- channels of nonpigmented ciliary epithelial cells.
The American journal of physiology 1999;276(3 Pt 1):C659-66.
1998: Claire H Mitchell; DA Carré; Alice M McGlinn; Richard A Stone; Mortimer M Civan
A release mechanism for stored ATP in ocular ciliary epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):7174-8.
1997: DA Carré; Claire H Mitchell; Kim Peterson-Yantorno; Miguel Coca-Prados; Mortimer M Civan
Adenosine stimulates Cl- channels of nonpigmented ciliary epithelial cells.
The American journal of physiology 1997;273(4 Pt 1):C1354-61.