FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Fraser Mitchell

Research Profile

Chemicals & Drugs

Procedures

Infusions, Intravenous

Concepts & Ideas

Co-author Network

Publications

TOP 3
Meg Perumal; Radhakrishna G Pillai; Henryk Barthel; Julius Leyton; John R Latigo; Martin Forster; Fraser Mitchell; Ann L Jackman; Eric O Aboagye
Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography.
David D Gibbs; Davinder S Theti; Nadya Wood; Matthew Green; Florence I Raynaud; Melanie Valenti; Martin D Forster; Fraser Mitchell; Vassilios Bavetsias; Elisa Henderson; Ann L Jackman
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
T Benepal; Ann L Jackman; Lynda Pyle; S Bate; Anthea Hardcastle; Wynne Aherne; Fraser Mitchell; Laura Simmons; Ruth Ruddle; Florence I Raynaud; M Gore
A phase I pharmacokinetic and pharmacodynamic study of BGC9331 and carboplatin in relapsed gynaecological malignancies.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Fraser Mitchell (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2006: Meg Perumal; Radhakrishna G Pillai; Henryk Barthel; Julius Leyton; John R Latigo; Martin Forster; Fraser Mitchell; Ann L Jackman; Eric O Aboagye
Redistribution of nucleoside transporters to the cell membrane provides a novel approach for imaging thymidylate synthase inhibition by positron emission tomography.
Cancer research 2006;66(17):8558-64.
2005: David D Gibbs; Davinder S Theti; Nadya Wood; Matthew Green; Florence I Raynaud; Melanie Valenti; Martin D Forster; Fraser Mitchell; Vassilios Bavetsias; Elisa Henderson; Ann L Jackman
BGC 945, a novel tumor-selective thymidylate synthase inhibitor targeted to alpha-folate receptor-overexpressing tumors.
Cancer research 2005;65(24):11721-8.
2005: T Benepal; Ann L Jackman; Lynda Pyle; S Bate; Anthea Hardcastle; Wynne Aherne; Fraser Mitchell; Laura Simmons; Ruth Ruddle; Florence I Raynaud; M Gore
A phase I pharmacokinetic and pharmacodynamic study of BGC9331 and carboplatin in relapsed gynaecological malignancies.
British journal of cancer 2005;93(8):868-75.
2003: Charlotte Rees; Philip Beale; Jose Manuel Trigo; Fraser Mitchell; Ann L Jackman; Robert Smith; Edwin Douglass; Ian Judson
Phase I trial of ZD9331, a nonpolyglutamatable thymidylate synthase inhibitor, given as a 5-day continuous infusion to patients with refractory solid malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(6):2049-55.
2003: Ruth Plummer; Charlotte Rees; Andrew Hughes; Philip Beale; Martin Highley; Jose Manuel Trigo; Sathyarathnarn Gokul; Ian Judson; Hilary Calvert; Ann L Jackman; Fraser Mitchell; Robert Smith; Edwin Douglass
A phase I trial of ZD9331, a water-soluble, nonpolyglutamatable, thymidylate synthase inhibitor.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1313-22.
2002: Vassilios Bavetsias; Lorraine A Skelton; F Yafai; Fraser Mitchell; Stuart C Wilson; B Allan; Ann L Jackman
The design and synthesis of water-soluble analogues of CB30865, a quinazolin-4-one-based antitumor agent.
Journal of medicinal chemistry 2002;45(17):3692-702.
2002: Hugo Ford; Fraser Mitchell; David Cunningham; David C Farrugia; Mark E Hill; Charlotte Rees; A Hilary Calvert; Ian R Judson; Ann L Jackman
Patterns of elevation of plasma 2'-deoxyuridine, a surrogate marker of thymidylate synthase (TS) inhibition, after administration of two different schedules of 5-fluorouracil and the specific TS inhibitors raltitrexed (Tomudex) and ZD9331.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(1):103-9.
2001: Clasina L Van der Wilt; Harold H J Backus; Kees Smid; L Comijn; Gijsbert Veerman; Dorine Wouters; Daphne Voorn; David G Priest; Marlene A Bunni; Fraser Mitchell; Ann L Jackman; Gerrit Jansen; Godefridus J Peters
Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors.
Cancer research 2001;61(9):3675-81.
2000: Fraser Mitchell; S Lynn; Ann L Jackman
Modified high-performance liquid chromatography assay for the measurement of 2'-deoxyuridine in human plasma and its application to pharmacodynamic studies of antimetabolite drugs.
Journal of chromatography. B, Biomedical sciences and applications 2000;744(2):351-8.
1998: Mike I Walton; Fraser Mitchell; G Wynne Aherne; C J Medlow; F Thomas Boyle; Ann L Jackman
The renal effects of the water-soluble, non-folylpolyglutamate synthetase-dependent thymidylate synthase inhibitor ZD9331 in mice.
British journal of cancer 1998;78(11):1457-63.