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James Mitchell

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Shingo Matsumoto; Hellmut Merkle; James B Mitchell; H Douglas Morris; Jeeva Munasinghe; Keita Saito; Sankaran Subramanian; Hironobu Yasui; Jan Henrik Ardenkjaer-Larsen; Rajani Choudhuri; Nallathamby Devasahayam; Alan P Koretsky; Martin J Lizak; Murali C Krishna
EPR oxygen imaging and hyperpolarized (13) C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Shingo Matsumoto; Hellmut Merkle; James B Mitchell; H Douglas Morris; Jeeva Munasinghe; Keita Saito; Sankaran Subramanian; Hironobu Yasui; Jan Henrik Ardenkjaer-Larsen; Rajani Choudhuri; Nallathamby Devasahayam; Alan P Koretsky; Martin J Lizak; Murali C Krishna
EPR oxygen imaging and hyperpolarized (13) C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Fei Li; James B Mitchell; Xiaoyan Pang; Chi Chen; John A Cook; Frank J Gonzalez; Changtao Jiang; Kristopher W Krausz; Murali C Krishna; Andrew D Patterson
Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.

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All Publications

2013: Shingo Matsumoto; Hellmut Merkle; James B Mitchell; H Douglas Morris; Jeeva Munasinghe; Keita Saito; Sankaran Subramanian; Hironobu Yasui; Jan Henrik Ardenkjaer-Larsen; Rajani Choudhuri; Nallathamby Devasahayam; Alan P Koretsky; Martin J Lizak; Murali C Krishna
EPR oxygen imaging and hyperpolarized (13) C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2013;69(5):spcone.
2013: Shingo Matsumoto; Hellmut Merkle; James B Mitchell; H Douglas Morris; Jeeva Munasinghe; Keita Saito; Sankaran Subramanian; Hironobu Yasui; Jan Henrik Ardenkjaer-Larsen; Rajani Choudhuri; Nallathamby Devasahayam; Alan P Koretsky; Martin J Lizak; Murali C Krishna
EPR oxygen imaging and hyperpolarized (13) C MRI of pyruvate metabolism as noninvasive biomarkers of tumor treatment response to a glycolysis inhibitor 3-bromopyruvate.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2013;69(5):1443-50.
2013: Fei Li; James B Mitchell; Xiaoyan Pang; Chi Chen; John A Cook; Frank J Gonzalez; Changtao Jiang; Kristopher W Krausz; Murali C Krishna; Andrew D Patterson
Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.
Journal of proteome research 2013;12(3):1369-76.
2012: Fuminori Hyodo; Murali C Krishna; Shingo Matsumoto; Ryan M Davis; Emi Hyodo; James B Mitchell
The relationship between tissue oxygenation and redox status using magnetic resonance imaging.
International journal of oncology 2012;41(6):2103-8.
2012: Bruce J Baum; Jaime Brahim; Peter D Burbelo; Clara C Chen; John A Chiorini; Deborah E Citrin; Ana P Cotrim; Stamatina Danielides; Corinne M Goldsmith; Shuying Liu; Linda McCullagh; James B Mitchell; Nikolay P Nikolov; Liesl K Nottingham; Nicholas J Patronas; Susan F Rudy; R James Turner; Carter Van Waes; Millie A Whatley; Changyu Zheng; Ilias Alevizos; Gabor G Illei
Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(47):19403-7.
2012: Ramiro Iglesias-Bartolome; Kantima Leelahavanichkul; James B Mitchell; Alfredo A Molinolo; Vyomesh Patel; Ana Cotrim; J Silvio Gutkind
mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis.
Cell stem cell 2012;11(3):401-14.
2012: Ana P Cotrim; James B Mitchell; Anastasia L Sowers; Abraham N Sunshine; Angela D Thetford; Masanobu Yoshikawa; Changyu Zheng; John A Cook; Bruce J Baum
Pharmacological protection from radiation ± cisplatin-induced oral mucositis.
International journal of radiation oncology, biology, physics 2012;83(4):1284-90.
2012: Sankaran Subramanian; Nallathamby Devasahayam; Shingo Matsumoto; James B Mitchell; Keita Saito; Murali C Krishna
Echo-based Single Point Imaging (ESPI): a novel pulsed EPR imaging modality for high spatial resolution and quantitative oximetry.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2012;218():105-14.
2012: Murali C Krishna; Shingo Matsumoto; Keita Saito; Sankaran Subramanian; Hironobu Yasui; Nallathamby Devasahayam; James B Mitchell
Electron paramagnetic resonance imaging of tumor pO₂.
Radiation research 2012;177(4):376-86.
2012: Keita Saito; Sankaran Subramanian; Jan Henrik Ardenkjaer-Larsen; Nallathamby Devasahayam; Martin J Lizak; Shingo Matsumoto; James B Mitchell; H Douglas Morris; Jeeva Munasinghe; Murali C Krishna
Transient decrease in tumor oxygenation after intravenous administration of pyruvate.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2012;67(3):801-7.
2012: Wilmarie Flores-Santana; Michael J Gorczynski; S Bruce King; James B Mitchell; Terry Moody; Mai E Shoman; Angela Thetford; Carlos Velázquez; Weibin Chen; Murali K Cherukuri; David A Wink
Nitroxide derivatives of non-steroidal anti-inflammatory drugs exert anti-inflammatory and superoxide dismutase scavenging properties in A459 cells.
British journal of pharmacology 2012;165(4b):1058-67.
2012: Keita Saito; Sankaran Subramanian; Hironobu Yasui; Nallathamby Devasahayam; J Silvio Gutkind; Shingo Matsumoto; James B Mitchell; Jeeva Munasinghe; Vyomesh Patel; Murali C Krishna
Longitudinal imaging studies of tumor microenvironment in mice treated with the mTOR inhibitor rapamycin.
PloS one 2012;7(11):e49456.
2011: Ryan M Davis; William DeGraff; Murali K Cherukuri; Anastasia L Sowers; Angela Thetford; Marcelino Bernardo; James B Mitchell
A novel nitroxide is an effective brain redox imaging contrast agent and in vivo radioprotector.
Free radical biology & medicine 2011;51(3):780-90.
2011: James B Mitchell
Chasing free radicals in cells and tissues.
Radiation research 2011;176(1):1-7.
2011: Ryan M Davis; James B Mitchell; Murali K Cherukuri
Nitroxides as cancer imaging agents.
Anti-cancer agents in medicinal chemistry 2011;11(4):347-58.
2011: Ryan M Davis; Shingo Matsumoto; Marcelino Bernardo; Anastasia L Sowers; Ken-Ichiro Matsumoto; Murali K Cherukuri; James B Mitchell
Magnetic resonance imaging of organic contrast agents in mice: capturing the whole-body redox landscape.
Free radical biology & medicine 2011;50(3):459-68.
2011: Rajani Choudhuri; William DeGraff; Janet Gamson; James B Mitchell; John A Cook
Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines.
Frontiers in oncology 2011;1():19.
2011: Anthony D Saleh; Jason E Savage; Benjamin P Soule; Liu Cao; William DeGraff; Curtis C Harris; David Ly; James B Mitchell; Nicole L Simone
Cellular stress induced alterations in microRNA let-7a and let-7b expression are dependent on p53.
PloS one 2011;6(10):e24429.
2011: Ken-ichiro Matsumoto; Fuminori Hyodo; Kazunori Anzai; Hideo Utsumi; James B Mitchell; Murali K Cherukuri
Brain redox imaging.
Methods in molecular biology (Clifton, N.J.) 2011;711():397-419.
2011: Atsuko Matsumoto; Ken-ichiro Matsumoto; Shingo Matsumoto; Fuminori Hyodo; Anastasia L Sowers; Janusz W Koscielniak; Nallathamby Devasahayam; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Intracellular hypoxia of tumor tissue estimated by noninvasive electron paramagnetic resonance oximetry technique using paramagnetic probes.
Biological & pharmaceutical bulletin 2011;34(1):142-5.
2010: Shingo Matsumoto; Hironobu Yasui; James B Mitchell; Murali K Cherukuri
Imaging cycling tumor hypoxia.
Cancer research 2010;70(24):10019-23.
2010: Hironobu Yasui; Shingo Matsumoto; Nallathamby Devasahayam; Jeeva Munasinghe; Rajani Choudhuri; Keita Saito; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Low-field magnetic resonance imaging to visualize chronic and cycling hypoxia in tumor-bearing mice.
Cancer research 2010;70(16):6427-36.
2010: Yuval Samuni; John A Cook; Rajani Choudhuri; William DeGraff; Anastasia L Sowers; Murali K Cherukuri; James B Mitchell
Inhibition of adipogenesis by Tempol in 3T3-L1 cells.
Free radical biology & medicine 2010;49(4):667-73.
2010: Yuval Samuni; Hisanari Ishii; Fuminori Hyodo; Uri Samuni; Murali K Cherukuri; Sara Goldstein; James B Mitchell
Reactive oxygen species mediate hepatotoxicity induced by the Hsp90 inhibitor geldanamycin and its analogs.
Free radical biology & medicine 2010;48(11):1559-63.
2010: John A Cook; Rajani Choudhuri; William DeGraff; Janet Gamson; James B Mitchell
Halofuginone enhances the radiation sensitivity of human tumor cell lines.
Cancer letters 2010;289(1):119-26.
2010: Aaron P Brown; Eun Joo Chung; Mary Ellen Urick; William P Shield; Anastasia L Sowers; Angela Thetford; Uma Shankavaram; James B Mitchell; Deborah Citrin
Evaluation of the fullerene compound DF-1 as a radiation protector.
Radiation oncology (London, England) 2010;5():34.
2010: Benjamin P Soule; Nicole L Simone; William DeGraff; Rajani Choudhuri; John A Cook; James B Mitchell
Loratadine dysregulates cell cycle progression and enhances the effect of radiation in human tumor cell lines.
Radiation oncology (London, England) 2010;5():8.
2009: Shingo Matsumoto; Hironobu Yasui; Sonny Batra; Yuichi Kinoshita; Marcelino Bernardo; Jeeva Munasinghe; Hideo Utsumi; Rajani Choudhuri; Nallathamby Devasahayam; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17898-903.
2009: Fuminori Hyodo; Gadisetti V R Chandramouli; Shingo Matsumoto; Ken-Ichiro Matsumoto; James B Mitchell; Murali K Cherukuri; Jeeva P Munasinghe
Estimation of tumor microvessel density by MRI using a blood pool contrast agent.
International journal of oncology 2009;35(4):797-804.
2009: Yuval Samuni; Wilmarie Flores-Santana; Murali K Cherukuri; James B Mitchell; David A Wink
The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation.
Free radical biology & medicine 2009;47(4):419-23.
2009: Hisanari Ishii; Rajani Choudhuri; Askale Mathias; Anastasia L Sowers; Kathleen C Flanders; John A Cook; James B Mitchell
Halofuginone mediated protection against radiation-induced leg contracture.
International journal of oncology 2009;35(2):315-9.
2009: Ken-Ichiro Matsumoto; Aya Okajo; Katsura Nagata; William G Degraff; Minako Nyui; Megumi Ueno; Ikuo Nakanishi; Toshihiko Ozawa; James B Mitchell; Murali K Cherukuri; Haruhiko Yamamoto; Kazutoyo Endo; Kazunori Anzai
Detection of free radical reactions in an aqueous sample induced by low linear-energy-transfer irradiation.
Biological & pharmaceutical bulletin 2009;32(4):542-7.
2009: Fuminori Hyodo; Shingo Matsumoto; Nallathamby Devasahayam; Christopher Dharmaraj; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Pulsed EPR imaging of nitroxides in mice.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2009;197(2):181-5.
2009: Christopher D Dharmaraj; Kishan Thadikonda; Anthony R Fletcher; Phuc N Doan; Nallathamby Devasahayam; Shingo Matsumoto; Calvin A Johnson; John A Cook; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Reconstruction for time-domain in vivo EPR 3D multigradient oximetric imaging--a parallel processing perspective.
International journal of biomedical imaging 2009;2009():528639.
2009: Nicole L Simone; Benjamin P Soule; David Ly; Anthony D Saleh; Jason E Savage; William DeGraff; John Cook; Curtis C Harris; David Gius; James B Mitchell
Ionizing radiation-induced oxidative stress alters miRNA expression.
PloS one 2009;4(7):e6377.
2008: Sanjeewani T Palayoor; James B Mitchell; David Cerna; William DeGraff; Molykutty John-Aryankalayil; C Norman Coleman
PX-478, an inhibitor of hypoxia-inducible factor-1alpha, enhances radiosensitivity of prostate carcinoma cells.
International journal of cancer. Journal international du cancer 2008;123(10):2430-7.
2008: Fuminori Hyodo; Benjamin P Soule; Ken-Ichiro Matsumoto; Shingo Matusmoto; John A Cook; Emi Hyodo; Anastasia L Sowers; Murali K Cherukuri; James B Mitchell
Assessment of tissue redox status using metabolic responsive contrast agents and magnetic resonance imaging.
The Journal of pharmacy and pharmacology 2008;60(8):1049-60.
2008: Kathleen C Flanders; Benjamin M Ho; Praveen R Arany; Christina Stuelten; Mizuko Mamura; Miya Okada Paterniti; Anastasia L Sowers; James B Mitchell; Anita B Roberts
Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.
The American journal of pathology 2008;173(1):68-76.
2008: Fuminori Hyodo; Kai-Hsiang Chuang; Artem G Goloshevsky; Agnieszka Sulima; Gary L Griffiths; James B Mitchell; Alan Koretsky; Murali K Cherukuri
Brain redox imaging using blood-brain barrier-permeable nitroxide MRI contrast agent.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(6):1165-74.
2008: Shingo Matsumoto; Fuminori Hyodo; Sankaran Subramanian; Nallathamby Devasahayam; Jeeva Munasinghe; Emi Hyodo; Chandramouli Gadisetti; John A Cook; James B Mitchell; Murali K Cherukuri
Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice.
The Journal of clinical investigation 2008;118(5):1965-73.
2008: Shingo Matsumoto; Michael G Espey; Hideo Utsumi; Nallathamby Devasahayam; Ken-Ichiro Matsumoto; Atsuko Matsumoto; Hiroshi Hirata; David A Wink; Periannan Kuppusamy; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Dynamic monitoring of localized tumor oxygenation changes using RF pulsed electron paramagnetic resonance in conscious mice.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;59(3):619-25.
2008: Zhanjun Guo; Mong-Hsun Tsai; Yih-Horng Shiao; Li-Han Chen; Mei-Ling Wei; Xing Lv; David Gius; John B Little; James B Mitchell; Eric Y Chuang
DNA (cytosine-5)-methyltransferase 1 as a mediator of mutant p53-determined p16(ink4A) down-regulation.
Journal of biomedical science 2008;15(2):163-8.
2008: Fuminori Hyodo; Sankaran Subramanian; Nallathamby Devasahayam; Ramachandran Murugesan; Ken-ichiro Matsumoto; James B Mitchell; Murali K Cherukuri
Evaluation of sub-microsecond recovery resonators for in vivo electron paramagnetic resonance imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;190(2):248-54.
2008: Fuminori Hyodo; Ramachandran Murugesan; Ken-Ichiro Matsumoto; Emi Hyodo; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Monitoring redox-sensitive paramagnetic contrast agent by EPRI, OMRI and MRI.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;190(1):105-12.
2007: Ana P Cotrim; Anastasia L Sowers; James B Mitchell; Bruce J Baum
Prevention of irradiation-induced salivary hypofunction by microvessel protection in mouse salivary glands.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(12):2101-6.
2007: Yukihiro Hama; Ken-Ichiro Matsumoto; Ramachandran Murugesan; Sankaran Subramanian; Nallathamby Devasahayam; Janusz W Koscielniak; Fuminori Hyodo; John A Cook; James B Mitchell; Murali K Cherukuri
Continuous wave EPR oximetric imaging at 300 MHz using radiofrequency power saturation effects.
Antioxidants & redox signaling 2007;9(10):1709-16.
2007: Benjamin P Soule; Fuminori Hyodo; Ken-Ichiro Matsumoto; Nicole L Simone; John A Cook; Murali K Cherukuri; James B Mitchell
Therapeutic and clinical applications of nitroxide compounds.
Antioxidants & redox signaling 2007;9(10):1731-43.
2007: Praveen R Arany; Kathleen C Flanders; William DeGraff; John Cook; James B Mitchell; Anita B Roberts
Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts.
Journal of dermatological science 2007;48(1):35-42.
2007: Benjamin P Soule; Jared M Brown; Nataliya M Kushnir-Sukhov; Nicole L Simone; James B Mitchell; Dean D Metcalfe
Effects of gamma radiation on FcepsilonRI and TLR-mediated mast cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3276-86.
2007: Ana P Cotrim; Fuminori Hyodo; Ken-Ichiro Matsumoto; Anastasia L Sowers; John A Cook; Bruce J Baum; Murali K Cherukuri; James B Mitchell
Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4928-33.
2007: Ken-ichiro Matsumoto; Sankaran Subramanian; Ramachandran Murugesan; James B Mitchell; Murali K Cherukuri
Spatially resolved biologic information from in vivo EPRI, OMRI, and MRI.
Antioxidants & redox signaling 2007;9(8):1125-41.
2007: Benjamin P Soule; Fuminori Hyodo; Ken-Ichiro Matsumoto; Nicole L Simone; John A Cook; Murali K Cherukuri; James B Mitchell
The chemistry and biology of nitroxide compounds.
Free radical biology & medicine 2007;42(11):1632-50.
2007: Mong-Hsun Tsai; John A Cook; Gadisetti V R Chandramouli; William DeGraff; Hailing Yan; Shuping Zhao; C Norman Coleman; James B Mitchell; Eric Y Chuang
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.
Cancer research 2007;67(8):3845-52.
2007: Nallathamby Devasahayam; Sankaran Subramanian; Ramachandran Murugesan; Fuminori Hyodo; Ken-Ichiro Matsumoto; James B Mitchell; Murali K Cherukuri
Strategies for improved temporal and spectral resolution in in vivo oximetric imaging using time-domain EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(4):776-83.
2007: Ken-Ichiro Matsumoto; Lawrence P Szajek; Murali K Cherukuri; John A Cook; Jurgen Seidel; Kelly Grimes; Joann Carson; Anastasia L Sowers; Sean English; Michael V Green; Stephen L Bacharach; William Eckelman; James B Mitchell
The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
International journal of oncology 2007;30(4):873-81.
2007: Nicole L Simone; Benjamin P Soule; Lynn H Gerber; Elizabeth Augustine; Sharon Smith; Rosemary M Altemus; James B Mitchell; Kevin A. Camphausen
Oral pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.
Radiation oncology (London, England) 2007;2():19.
2006: Fuminori Hyodo; Ken-Ichiro Matsumoto; Atsuko Matsumoto; James B Mitchell; Murali K Cherukuri
Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents.
Cancer research 2006;66(20):9921-8.
2006: Douglas D Thomas; Lisa A Ridnour; Michael G Espey; Sonia Donzelli; Stefan Ambs; S Perwez Hussain; Curtis C Harris; William DeGraff; David D Roberts; James B Mitchell; David A Wink
Superoxide fluxes limit nitric oxide-induced signaling.
The Journal of biological chemistry 2006;281(36):25984-93.
2006: Aya Okajo; Ken-ichiro Matsumoto; James B Mitchell; Murali K Cherukuri; Kazutoyo Endo
Competition of nitroxyl contrast agents as an in vivo tissue redox probe: comparison of pharmacokinetics by the bile flow monitoring (BFM) and blood circulating monitoring (BCM) methods using X-band EPR and simulation of decay profiles.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(2):422-31.
2006: Ken-ichiro Matsumoto; Marcelino Bernardo; Sankaran Subramanian; Peter Choyke; James B Mitchell; Murali K Cherukuri; Martin J Lizak
MR assessment of changes of tumor in response to hyperbaric oxygen treatment.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(2):240-6.
2006: Bruce J Baum; Changyu Zheng; Ana P Cotrim; Corinne M Goldsmith; Jane C Atkinson; Jaime Brahim; John A Chiorini; Antonis Voutetakis; Rose Anne Leakan; Carter Van Waes; James B Mitchell; Christine Delporte; Songlin Wang; Stephen M Kaminsky; Gabor G Illei
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.
Biochimica et biophysica acta 2006;1758(8):1071-7.
2006: John A Cook; Eric Y Chuang; Mong-Hsun Tsai; Deborah Coffin; William DeGraff; Anastasia L Sowers; James B Mitchell
Radiation-induced changes in gene-expression profiles for the SCC VII tumor cells grown in vitro and in vivo.
Antioxidants & redox signaling 2006;8(7-8):1263-72.
2006: Ken-ichiro Matsumoto; Sankaran Subramanian; Nallathamby Devasahayam; Thirumaran Aravalluvan; Ramachandran Murugesan; John A Cook; James B Mitchell; Murali K Cherukuri
Electron paramagnetic resonance imaging of tumor hypoxia: enhanced spatial and temporal resolution for in vivo pO2 determination.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(5):1157-63.
2006: Ken-Ichiro Matsumoto; Fuminori Hyodo; Atsuko Matsumoto; Alan Koretsky; Anastasia L Sowers; James B Mitchell; Murali K Cherukuri
High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2455-62.
2006: Eric Y Chuang; Xi Chen; Mong-Hsun Tsai; Hailing Yan; Chuan-Yuan Li; James B Mitchell; Hatsumi Nagasawa; Paul F Wilson; Yuanlin Peng; Markus M Fitzek; Joel S Bedford; John B Little
Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma.
Cancer research 2006;66(7):3428-33.
2006: Mong-Hsun Tsai; Xinbin Chen; Gadisetti V R Chandramouli; Yidong Chen; H Yan; S Zhao; P Keng; H L Liber; C Norman Coleman; James B Mitchell; Eric Y Chuang
Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells.
Oncogene 2006;25(4):622-32.
2006: Linda W Chan; Sebastien Hapdey; Sean English; Jurgen Seidel; Joann Carson; Anastasia L Sowers; Murali K Cherukuri; Michael V Green; James B Mitchell; Stephen L Bacharach
The influence of tumor oxygenation on (18)F-FDG (fluorine-18 deoxyglucose) uptake: a mouse study using positron emission tomography (PET).
Radiation oncology (London, England) 2006;1():3.
2006: Kinjal Patel; Yifan Chen; Kathryn Dennehy; Jonathan Blau; Stephanie Connors; Margarida Mendonca; Margaret Tarpey; Murali Krishna; James B Mitchell; William J Welch; Christopher Wilcox
Acute antihypertensive action of nitroxides in the spontaneously hypertensive rat.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R37-43.
2005: Joe Z Sostaric; Norio Miyoshi; Péter Riesz; William DeGraff; James B Mitchell
n-Alkyl glucopyranosides completely inhibit ultrasound-induced cytolysis.
Free radical biology & medicine 2005;39(12):1539-48.
2005: Atsuko Matsumoto; Shingo Matsumoto; Anastasia L Sowers; Janusz W Koscielniak; Nancy J Trigg; Periannan Kuppusamy; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri; Ken-Ichiro Matsumoto
Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(6):1530-5.
2005: Carter Van Waes; Angela A Chang; Peter F Lebowitz; Colleen H Druzgal; Zhong Chen; Yusri A Elsayed; John B Sunwoo; Susan F Rudy; John C Morris; James B Mitchell; Kevin A. Camphausen; David Gius; Julian Adams; Edward A Sausville; BA Conley
Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma.
International journal of radiation oncology, biology, physics 2005;63(5):1400-12.
2005: Ana P Cotrim; Anastasia L Sowers; Beatrijs M Lodde; Joseph M Vitolo; Albert Kingman; Angelo Russo; James B Mitchell; Bruce J Baum
Kinetics of tempol for prevention of xerostomia following head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7564-8.
2005: Kevin A. Camphausen; Deborah Citrin; Murali K Cherukuri; James B Mitchell
Implications for tumor control during protection of normal tissues with antioxidants.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(24):5455-7.
2005: Thierry Muanza; Ana P Cotrim; Mathew McAuliffe; Anastasia L Sowers; Bruce J Baum; John A Cook; Felix Feldchtein; Paul Amazeen; C Norman Coleman; James B Mitchell
Evaluation of radiation-induced oral mucositis by optical coherence tomography.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5121-7.
2005: Shingo Matsumoto; Hideo Utsumi; Thirumaran Aravalluvan; Ken-Ichiro Matsumoto; Atsuko Matsumoto; Nallathamby Devasahayam; Anastasia L Sowers; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Influence of proton T1 on oxymetry using Overhauser enhanced magnetic resonance imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(1):213-7.
2005: Ken-ichiro Matsumoto; Aya Okajo; Takenori Kobayashi; James B Mitchell; Murali K Cherukuri; Kazutoyo Endo
Estimation of free radical formation by beta-ray irradiation in rat liver.
Journal of biochemical and biophysical methods 2005;63(2):79-90.
2005: Simeng Suy; James B Mitchell; Amram Samuni; Susette Mueller; Usha N Kasid
Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice.
Cancer 2005;103(6):1302-13.
2005: Mong-Hsun Tsai; Hailing Yan; Xi Chen; Gadisetti V R Chandramouli; Shuping Zhao; Deborah Coffin; C Norman Coleman; James B Mitchell; Eric Y Chuang
Evaluation of hybridization conditions for spotted oligonucleotide-based DNA microarrays.
Molecular biotechnology 2005;29(3):221-4.
2005: Amram Samuni; Usha N Kasid; Eric Y Chuang; Simeng Suy; William DeGraff; Murali K Cherukuri; Angelo Russo; James B Mitchell
Effects of hypoxia on radiation-responsive stress-activated protein kinase, p53, and caspase 3 signals in TK6 human lymphoblastoid cells.
Cancer research 2005;65(2):579-86.
2004: Hisataka Kobayashi; Koen Reijnders; Sean English; Alexander T Yordanov; Diane E Milenic; Anastasia L Sowers; Deborah Citrin; Murali K Cherukuri; Thomas Waldmann; James B Mitchell; Martin W Brechbiel
Application of a macromolecular contrast agent for detection of alterations of tumor vessel permeability induced by radiation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7712-20.
2004: Amram Samuni; William DeGraff; John A Cook; Murali K Cherukuri; Angelo Russo; James B Mitchell
The effects of antioxidants on radiation-induced apoptosis pathways in TK6 cells.
Free radical biology & medicine 2004;37(10):1648-55.
2004: James B Mitchell; Kenichi Yamada; Nallathamby Devasahayam; John A Cook; Sankaran Subramanian; Murali K Cherukuri
Novel functional imaging for tissue oxygen concentration and redox status.
The Journal of nutrition 2004;134(11):3210S.
2004: David Gius; Hengmi Cui; C Matthew Bradbury; John Cook; Deedee K Smart; Shuping Zhao; Lynn Young; Sheri A Brandenburg; Yali Hu; Kheem S Bisht; Allen S Ho; David Mattson; Lunching Sun; Peter J Munson; Eric Y Chuang; James B Mitchell; Andrew P Feinberg
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
Cancer cell 2004;6(4):361-71.
2004: Ken-Ichiro Matsumoto; Sean English; John Yoo; Ken-Ichi Yamada; Nallathamby Devasahayam; John A Cook; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Pharmacokinetics of a triarylmethyl-type paramagnetic spin probe used in EPR oximetry.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;52(4):885-92.
2004: Amy Loercher; Tin-Lap Lee; Justin L Ricker; April Howard; Joel Geoghegen; Zhong Chen; John B Sunwoo; Raquel Sitcheran; Eric Y Chuang; James B Mitchell; Albert S Baldwin; Carter Van Waes
Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma.
Cancer research 2004;64(18):6511-23.
2004: Andreas Rosenwald; Eric Y Chuang; R Eric Davis; Adrian Wiestner; Ash A Alizadeh; Diane C Arthur; James B Mitchell; Gerald E Marti; Daniel H Fowler; Wyndham H Wilson; Louis M Staudt
Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response.
Blood 2004;104(5):1428-34.
2004: Ken-Ichiro Matsumoto; Murali K Cherukuri; James B Mitchell
Novel pharmacokinetic measurement using electron paramagnetic resonance spectroscopy and simulation of in vivo decay of various nitroxyl spin probes in mouse blood.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1076-83.
2004: Sankaran Subramanian; Ken-Ichiro Matsumoto; James B Mitchell; Murali K Cherukuri
Radio frequency continuous-wave and time-domain EPR imaging and Overhauser-enhanced magnetic resonance imaging of small animals: instrumental developments and comparison of relative merits for functional imaging.
NMR in biomedicine 2004;17(5):263-94.
2004: John A Cook; David Gius; David A Wink; Murali K Cherukuri; Angelo Russo; James B Mitchell
Oxidative stress, redox, and the tumor microenvironment.
Seminars in radiation oncology 2004;14(3):259-66.
2004: Yuval Samuni; Janet Gamson; Amram Samuni; Kenichi Yamada; Angelo Russo; Murali K Cherukuri; James B Mitchell
Factors influencing nitroxide reduction and cytotoxicity in vitro.
Antioxidants & redox signaling 2004;6(3):587-95.
2004: Nallathamby Devasahayam; Ramachandran Murugesan; Ken-ichiro Matsumoto; James B Mitchell; John A Cook; Sankaran Subramanian; Murali K Cherukuri
Tailored sinc pulses for uniform excitation and artifact-free radio frequency time-domain EPR imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;168(1):110-7.
2004: Sandhya Xavier; Ester Piek; Makiko Fujii; Delphine Javelaud; Alain Mauviel; Kathleen C Flanders; Amram Samuni; Angelina Felici; Michael Reiss; Shai Yarkoni; Anastasia L Sowers; James B Mitchell; Anita B Roberts; Angelo Russo
Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
The Journal of biological chemistry 2004;279(15):15167-76.
2004: Joseph M Vitolo; Ana P Cotrim; Anastasia L Sowers; Angelo Russo; Robert B Wellner; Stanley R Pillemer; James B Mitchell; Bruce J Baum
The stable nitroxide tempol facilitates salivary gland protection during head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1807-12.
2004: Koen Reijnders; Sean English; Murali K Cherukuri; John A Cook; Anastasia L Sowers; James B Mitchell; Yantian Zhang
Influence of body temperature on the BOLD effect in murine SCC tumors.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;51(2):389-93.
2003: Kheem S Bisht; C Matthew Bradbury; David Mattson; Aradhana Kaushal; Anastasia L Sowers; Stephanie Markovina; Karen L Ortiz; Leah K Sieck; Jennifer S. Isaacs; Martin W Brechbiel; James B Mitchell; Leonard M Neckers; David Gius
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
Cancer research 2003;63(24):8984-95.
2003: Kathleen C Flanders; Christopher Major; Alidad Arabshahi; Ekinadese E Aburime; Miya H Okada; Makiko Fujii; Timothy Blalock; Gregory Schultz; Anastasia L Sowers; Mario A Anzano; James B Mitchell; Angelo Russo; Anita B Roberts
Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin.
The American journal of pathology 2003;163(6):2247-57.
2003: Ken-ichiro Matsumoto; Baby Chandrika; Joost A B Lohman; James B Mitchell; Murali K Cherukuri; Sankaran Subramanian
Application of continuous-wave EPR spectral-spatial image reconstruction techniques for in vivo oxymetry: comparison of projection reconstruction and constant-time modalities.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(4):865-74.
2003: Andrew G Taube; Sankaran Subramanian; Ramachandran Murugesan; Nallathamby Devasahayam; James B Mitchell; Murali K Cherukuri; John A Cook
An application system for automation of constant-time radio frequency electron paramagnetic resonance imaging.
Computer methods and programs in biomedicine 2003;72(2):127-38.
2003: William G De Graff; L S Myers; James B Mitchell; Stephen M Hahn
Protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity by 3,4-dihydroxybenzoic acid.
International journal of oncology 2003;23(1):159-63.
2003: Christopher Kennedy; Harvey I Pass; James B Mitchell
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Free radical biology & medicine 2003;34(11):1447-57.
2003: C Norman Coleman; William F Blakely; John R Fike; Thomas J MacVittie; Noelle F Metting; James B Mitchell; John E Moulder; R Julian Preston; Thomas M Seed; Helen B Stone; Philip J Tofilon; Rosemary S L Wong
Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001.
Radiation research 2003;159(6):812-34.
2003: Amram Samuni; Eric Y Chuang; Murali K Cherukuri; William Stein; William DeGraff; Angelo Russo; James B Mitchell
Semiquinone radical intermediate in catecholic estrogen-mediated cytotoxicity and mutagenesis: chemoprevention strategies with antioxidants.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5390-5.
2003: David A Wink; James B Mitchell
Nitric oxide and cancer: an introduction.
Free radical biology & medicine 2003;34(8):951-4.
2003: William Stein; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
EPR imaging of vascular changes in oxygen in response to carbogen breathing.
Advances in experimental medicine and biology 2003;510():231-6.
2003: James B Mitchell; Sandhya Xavier; Anne M DeLuca; Anastasia L Sowers; John A Cook; Murali K Cherukuri; Stephen M Hahn; Angelo Russo
A low molecular weight antioxidant decreases weight and lowers tumor incidence.
Free radical biology & medicine 2003;34(1):93-102.
2002: Sandhya Xavier; Ken-ichi Yamada; Amram Samuni; Amram Samuni; William DeGraff; Murali K Cherukuri; James B Mitchell
Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage.
Biochimica et biophysica acta 2002;1573(2):109-20.
2002: Yao-Yu Eric Chuang; Yidong Chen; V R Chandramouli; John A Cook; Deborah Coffin; Mong-Hsun Tsai; William DeGraff; Hailing Yan; Shuping Zhao; Angelo Russo; Edison Liu; James B Mitchell
Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.
Cancer research 2002;62(21):6246-54.
2002: Matthew M Poggi; Glenn S Kroog; Angelo Russo; Christine Muir; John Cook; Judith Smith; James B Mitchell; Laurie L Herscher
Phase I study of weekly gemcitabine as a radiation sensitizer for unresectable pancreatic cancer.
International journal of radiation oncology, biology, physics 2002;54(3):670-6.
2002: Govindasamy Ilangovan; Haiquan Li; Jay L Zweier; Murali K Cherukuri; James B Mitchell; Periannan Kuppusamy
In vivo measurement of regional oxygenation and imaging of redox status in RIF-1 murine tumor: effect of carbogen-breathing.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(4):723-30.
2002: Ramachandran Murugesan; Sean English; Koen Reijnders; Ken-Ichi Yamada; John A Cook; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Fluorine electron double resonance imaging for 19F MRI in low magnetic fields.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(3):523-9.
2002: Sankaran Subramanian; Nallathamby Devasahayam; Ramachandran Murugesan; Kenichi Yamada; John Cook; Andrew Taube; James B Mitchell; Joost A B Lohman; Murali K Cherukuri
Single-point (constant-time) imaging in radiofrequency Fourier transform electron paramagnetic resonance.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(2):370-9.
2002: Amram Samuni; Sara Goldstein; Angelo Russo; James B Mitchell; Murali K Cherukuri; Pedatsur Neta
Kinetics and mechanism of hydroxyl radical and OH-adduct radical reactions with nitroxides and with their hydroxylamines.
Journal of the American Chemical Society 2002;124(29):8719-24.
2002: Amram Samuni; Murali K Cherukuri; William DeGraff; Angelo Russo; Roy P Planalp; Martin W Brechbiel; James B Mitchell
Mechanisms underlying the cytotoxic effects of Tachpyr--a novel metal chelator.
Biochimica et biophysica acta 2002;1571(3):211-8.
2002: Ken-Ichi Yamada; P Kuppusamy; Sean English; John Yoo; A Irie; Sankaran Subramanian; James B Mitchell; Murali K Cherukuri
Feasibility and assessment of non-invasive in vivo redox status using electron paramagnetic resonance imaging.
Acta radiologica (Stockholm, Sweden : 1987) 2002;43(4):433-40.
2002: Alexander T Yordanov; Ken-ichi Yamada; Murali K Cherukuri; Angelo Russo; John Yoo; Sean English; James B Mitchell; Martin W Brechbiel
Acyl-protected hydroxylamines as spin label generators for EPR brain imaging.
Journal of medicinal chemistry 2002;45(11):2283-8.
2002: Katrina M Miranda; Ken-ichi Yamada; Michael G Espey; Douglas D Thomas; William DeGraff; James B Mitchell; Murali K Cherukuri; Carol A. Colton; David A Wink
Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite.
Archives of biochemistry and biophysics 2002;401(2):134-44.
2002: Amram Samuni; William DeGraff; Murali K Cherukuri; James B Mitchell
Nitroxides as antioxidants: Tempol protects against EO9 cytotoxicity.
Molecular and cellular biochemistry 2002;234-235(1-2):327-33.
2002: Sara Goldstein; Amram Samuni; Yaacov Aronovitch; Dina Godinger; Angelo Russo; James B Mitchell
Kinetics of paraquat and copper reactions with nitroxides: the effects of nitroxides on the aerobic and anoxic toxicity of paraquat.
Chemical research in toxicology 2002;15(5):686-91.
2002: Sankaran Subramanian; Ken-Ichi Yamada; Akira Irie; Ramachandran Murugesan; John A Cook; Nallathamby Devasahayam; Gooitzen van Dam; James B Mitchell; Murali K Cherukuri
Noninvasive in vivo oximetric imaging by radiofrequency FT EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(5):1001-8.
2002: Kathleen C Flanders; Catherine D Sullivan; Makiko Fujii; Anastasia L Sowers; Mario A Anzano; Alidad Arabshahi; Christopher Major; Chuxia Deng; Angelo Russo; James B Mitchell; Anita B Roberts
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation.
The American journal of pathology 2002;160(3):1057-68.
2002: Murali K Cherukuri; Sean English; Kenichi Yamada; John Yoo; Ramachandran Murugesan; Nallathamby Devasahayam; John A Cook; Klaes Golman; Jan Henrik Ardenkjaer-Larsen; Sankaran Subramanian; James B Mitchell
Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2216-21.
2002: James B Mitchell; Murali K Cherukuri
Nitroxides as radiation protectors.
Military medicine 2002;167(2 Suppl):49-50.
2002: Ken-Ichi Yamada; Ramachandran Murugesan; Nallathamby Devasahayam; John A Cook; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Evaluation and comparison of pulsed and continuous wave radiofrequency electron paramagnetic resonance techniques for in vivo detection and imaging of free radicals.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;154(2):287-97.
2002: Periannan Kuppusamy; Haiquan Li; Govindasamy Ilangovan; Arturo J Cardounel; Jay L Zweier; Kenichi Yamada; Murali K Cherukuri; James B Mitchell
Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.
Cancer research 2002;62(1):307-12.
2001: Matthew M Poggi; C Norman Coleman; James B Mitchell
Sensitizers and protectors of radiation and chemotherapy.
Current problems in cancer 2001;25(6):334-411.
2001: Anita B Roberts; Ester Piek; Erwin P Böttinger; Gillian S Ashcroft; James B Mitchell; Kathleen C Flanders
Is Smad3 a major player in signal transduction pathways leading to fibrogenesis?
Chest 2001;120(1 Suppl):43S-47S.
2001: James B Mitchell; Murali K Cherukuri; Periannan Kuppusamy; John A Cook; Angelo Russo
Protection against oxidative stress by nitroxides.
Experimental biology and medicine (Maywood, N.J.) 2001;226(7):620-1.
2001: Amram Samuni; William DeGraff; Murali K Cherukuri; James B Mitchell
Cellular sites of H2O2-induced damage and their protection by nitroxides.
Biochimica et biophysica acta 2001;1525(1-2):70-6.
2001: R Ogawa; R Pacelli; Michael G Espey; K M Miranda; N Friedman; S M Kim; G Cox; James B Mitchell; David A Wink; Angelo Russo
Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and NO donors: insights into listeriocidal activity of oxidative and nitrosative stress.
Free radical biology & medicine 2001;30(3):268-76.
2001: John B Sunwoo; Laurie L Herscher; Glenn S Kroog; Giovana R Thomas; Frank G Ondrey; Dianne C Duffey; BI Solomon; C Boss; Paul S Albert; L McCullugh; Susan F Rudy; Christine Muir; S Zhai; William D Figg; John A Cook; James B Mitchell; Carter Van Waes
Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(3):800-11.
2001: Amram Samuni; M Afeworki; William Stein; Alexander T Yordanov; William DeGraff; Murali K Cherukuri; James B Mitchell; Martin W Brechbiel
Multifunctional antioxidant activity of HBED iron chelator.
Free radical biology & medicine 2001;30(2):170-7.
2001: Murali K Cherukuri; S Subramanian; P Kuppusamy; James B Mitchell
Magnetic resonance imaging for in vivo assessment of tissue oxygen concentration.
Seminars in radiation oncology 2001;11(1):58-69.
2000: T Kato; Dianne C Duffey; Frank G Ondrey; Gang Dong; Zhong Chen; John A Cook; James B Mitchell; Carter Van Waes
Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kappaB.
Head & neck 2000;22(8):748-59.
2000: Qun Zhou; PI Fukushima; William DeGraff; James B Mitchell; Maryalice Stetler-Stevenson; A Ashkenazi; Patricia S Steeg
Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1.
Cancer research 2000;60(10):2611-5.
2000: Stephen M Hahn; Murali K Cherukuri; Anne M DeLuca; Deborah Coffin; James B Mitchell
Evaluation of the hydroxylamine Tempol-H as an in vivo radioprotector.
Free radical biology & medicine 2000;28(6):953-8.
2000: M Afeworki; Gooitzen van Dam; Nallathamby Devasahayam; Ramachandran Murugesan; John Cook; Deborah Coffin; J H Larsen; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Three-dimensional whole body imaging of spin probes in mice by time-domain radiofrequency electron paramagnetic resonance.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;43(3):375-82.
2000: Y Vodovotz; M S Lucia; A M DeLucca; James B Mitchell; Jeffrey B Kopp
Reduced hematopoietic function and enhanced radiosensitivity of transforming growth factor-beta1 transgenic mice.
International journal of cancer. Journal international du cancer 2000;90(1):13-21.
2000: James B Mitchell; Angelo Russo; Periannan Kuppusamy; Murali K Cherukuri
Radiation, radicals, and images.
Annals of the New York Academy of Sciences 2000;899():28-43.
2000: Eric J Bernhard; James B Mitchell; Dennis F Deen; M Cardell; David I Rosenthal; J M Brown
Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent.
Cancer research 2000;60(1):86-91.
2000: Nallathamby Devasahayam; Sankaran Subramanian; Ramachandran Murugesan; John A Cook; M Afeworki; rolf tschudin; James B Mitchell; Murali K Cherukuri
Parallel coil resonators for time-domain radiofrequency electron paramagnetic resonance imaging of biological objects.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;142(1):168-76.
1999: Laurie L Herscher; John A Cook; R Pacelli; Harvey I Pass; Angelo Russo; James B Mitchell
Principles of chemoradiation: theoretical and practical considerations.
Oncology (Williston Park, N.Y.) 1999;13(10 Suppl 5):11-22.
1999: Stephen M Hahn; Frank J Sullivan; Anne M DeLuca; J D Bacher; J Liebmann; Murali K Cherukuri; Deborah Coffin; James B Mitchell
Hemodynamic effect of the nitroxide superoxide dismutase mimics.
Free radical biology & medicine 1999;27(5-6):529-35.
1999: Sankaran Subramanian; Ramachandran Murugesan; Nallathamby Devasahayam; John A Cook; M Afeworki; Thomas J Pohida; rolf tschudin; James B Mitchell; Murali K Cherukuri
High-speed data acquisition system and receiver configurations for time-domain radiofrequency electron paramagnetic resonance spectroscopy and imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1999;137(2):379-88.
1999: Stephen M Hahn; A Russo; J A Cook; James B Mitchell
A multidrug-resistant breast cancer cell line induced by weekly exposure to doxorubicin.
International journal of oncology 1999;14(2):273-9.
1999: Y Samuni; Deborah Coffin; Anne M DeLuca; William DeGraff; D J Venson; I Ambudkar; Mordechai Chevion; James B Mitchell
The use of Zn-desferrioxamine for radioprotection in mice, tissue culture, and isolated DNA.
Cancer research 1999;59(2):405-9.
1999: Y Vodovotz; Deborah Coffin; Anne M DeLuca; LC McKinney; John A Cook; David A Wink; James B Mitchell
Induction of nitric oxide production in infiltrating leukocytes following in vivo irradiation of tumor-bearing mice.
Radiation oncology investigations 1999;7(2):86-97.
1999: David A Wink; Y Vodovotz; Matthew B Grisham; William DeGraff; J C Cook; R Pacelli; M Krishna; James B Mitchell
Antioxidant effects of nitric oxide.
Methods in enzymology 1999;301():413-24.
1998: Stephen M Hahn; Anne M DeLuca; Deborah Coffin; Murali K Cherukuri; James B Mitchell
In vivo radioprotection and effects on blood pressure of the stable free radical nitroxides.
International journal of radiation oncology, biology, physics 1998;42(4):839-42.
1998: James B Mitchell; William DeGraff; S Kim; John A Cook; Janet Gamson; D Christodoulou; Martin Feelisch; David A Wink
Redox generation of nitric oxide to radiosensitize hypoxic cells.
International journal of radiation oncology, biology, physics 1998;42(4):795-8.
1998: David A Wink; James B Mitchell
Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide.
Free radical biology & medicine 1998;25(4-5):434-56.
1998: Murali K Cherukuri; William DeGraff; O H Hankovszky; Cecília Sár; Tamás Kálai; J Jeko; Angelo Russo; James B Mitchell; Kálmán Hideg
Studies of structure-activity relationship of nitroxide free radicals and their precursors as modifiers against oxidative damage.
Journal of medicinal chemistry 1998;41(18):3477-92.
1998: Murali K Cherukuri; Periannan Kuppusamy; M Afeworki; Jay L Zweier; John A Cook; Sankaran Subramanian; James B Mitchell
Development of functional electron paramagnetic resonance imaging.
Breast disease 1998;10(3-4):209-20.
1998: Simeng Suy; James B Mitchell; Desiree Ehleiter; Adriana Haimovitz-Friedman; Usha N Kasid
Nitroxides tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells.
The Journal of biological chemistry 1998;273(28):17871-8.
1998: David A Wink; Y Vodovotz; John A Cook; Murali K Cherukuri; S Kim; Deborah Coffin; William DeGraff; Anne M DeLuca; J Liebmann; James B Mitchell
The role of nitric oxide chemistry in cancer treatment.
Biochemistry. Biokhimii͡a 1998;63(7):802-9.
1998: M Afeworki; N R Miller; Nallathamby Devasahayam; John Cook; James B Mitchell; Sankaran Subramanian; Murali K Cherukuri
Preparation and EPR studies of lithium phthalocyanine radical as an oxymetric probe.
Free radical biology & medicine 1998;25(1):72-8.
1998: Periannan Kuppusamy; M Afeworki; RA Shankar; Deborah Coffin; Murali K Cherukuri; Stephen M Hahn; James B Mitchell; Jay L Zweier
In vivo electron paramagnetic resonance imaging of tumor heterogeneity and oxygenation in a murine model.
Cancer research 1998;58(7):1562-8.
1998: C Theodossiou; John A Cook; J Fisher; D Teague; J E Liebmann; A Russo; James B Mitchell
Interaction of gemcitabine with paclitaxel and cisplatin in human tumor cell lines.
International journal of oncology 1998;12(4):825-32.
1998: David A Wink; Martin Feelisch; Jon M Fukuto; D Chistodoulou; David Jourd'heuil; Matthew B Grisham; Y Vodovotz; John A Cook; M Krishna; William DeGraff; S Kim; Janet Gamson; James B Mitchell
The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.
Archives of biochemistry and biophysics 1998;351(1):66-74.
1998: Laurie L Herscher; Stephen M Hahn; Glenn S Kroog; Harvey I Pass; BK Temeck; Barry Goldspiel; John Cook; James B Mitchell; J Liebmann
Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(2):635-41.
1998: Y Vodovotz; Jeffrey B Kopp; H Takeguchi; Shashi Shrivastav; Deborah Coffin; M S Lucia; James B Mitchell; R Webber; John J Letterio; David A Wink; A B Roberts
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice.
Journal of leukocyte biology 1998;63(1):31-9.
1997: Ramachandran Murugesan; John A Cook; Nallathamby Devasahayam; M Afeworki; Sankaran Subramanian; rolf tschudin; J A Larsen; James B Mitchell; Angelo Russo; Murali K Cherukuri
In vivo imaging of a stable paramagnetic probe by pulsed-radiofrequency electron paramagnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(3):409-14.
1997: David A Wink; John A Cook; Soo-Youl Kim; Y Vodovotz; R Pacelli; Murali K Cherukuri; Angelo Russo; James B Mitchell; David Jourd'heuil; AM Miles; Matthew B Grisham
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates. Chemical aspects involved in the balance between oxidative and nitrosative stress.
The Journal of biological chemistry 1997;272(17):11147-51.
1997: A Y Chen; P Okunieff; Yves Pommier; James B Mitchell
Mammalian DNA topoisomerase I mediates the enhancement of radiation cytotoxicity by camptothecin derivatives.
Cancer research 1997;57(8):1529-36.
1997: David A Wink; John A Cook; D Christodoulou; Murali K Cherukuri; R Pacelli; S Kim; William DeGraff; Janet Gamson; Y Vodovotz; Angelo Russo; James B Mitchell
Nitric oxide and some nitric oxide donor compounds enhance the cytotoxicity of cisplatin.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(1):88-94.
1997: Stephen M Hahn; James B Mitchell; E Shacter
Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage.
Free radical biology & medicine 1997;23(6):879-84.
1997: John A Cook; Murali K Cherukuri; R Pacelli; William DeGraff; J Liebmann; James B Mitchell; Angelo Russo; David A Wink
Nitric oxide enhancement of melphalan-induced cytotoxicity.
British journal of cancer 1997;76(3):325-34.
1997: P Twomey; J Taira; William DeGraff; James B Mitchell; Angelo Russo; Murali K Cherukuri; O H Hankovszky; L Frank; Kálmán Hideg
Direct evidence for in vivo nitroxide free radical production from a new antiarrhythmic drug by EPR spectroscopy.
Free radical biology & medicine 1997;22(5):909-16.
1997: Stephen M Hahn; Frank J Sullivan; Anne M DeLuca; Murali K Cherukuri; NG Wersto; D Venzon; Angelo Russo; James B Mitchell
Evaluation of tempol radioprotection in a murine tumor model.
Free radical biology & medicine 1997;22(7):1211-6.
1996: Murali K Cherukuri; Amram Samuni; J Taira; S Goldstein; James B Mitchell; Angelo Russo
Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism.
The Journal of biological chemistry 1996;271(42):26018-25.
1996: D Cuscela; Deborah Coffin; G P Lupton; John A Cook; Murali K Cherukuri; Robert F Bonner; James B Mitchell
Protection from radiation-induced alopecia with topical application of nitroxides: fractionated studies.
The cancer journal from Scientific American 1996;2(5):273-8.
1996: David A Wink; John A Cook; R Pacelli; William DeGraff; Janet Gamson; J Liebmann; Murali K Cherukuri; James B Mitchell
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection.
Archives of biochemistry and biophysics 1996;331(2):241-8.
1996: James B Mitchell; John A Cook; Murali K Cherukuri; William DeGraff; Janet Gamson; J Fisher; D Christodoulou; David A Wink
Radiation sensitisation by nitric oxide releasing agents.
The British journal of cancer. Supplement 1996;27():S181-4.
1996: John A Cook; S Y Kim; D Teague; Murali K Cherukuri; R Pacelli; James B Mitchell; Y Vodovotz; Raymond W Nims; D Christodoulou; AM Miles; Matthew B Grisham; David A Wink
Convenient colorimetric and fluorometric assays for S-nitrosothiols.
Analytical biochemistry 1996;238(2):150-8.
1995: David A Wink; John A Cook; R Pacelli; J Liebmann; Murali K Cherukuri; James B Mitchell
Nitric oxide (NO) protects against cellular damage by reactive oxygen species.
Toxicology letters 1995;82-83():221-6.
1995: R Pacelli; David A Wink; John A Cook; Murali K Cherukuri; William DeGraff; N Friedman; M Tsokos; Amram Samuni; James B Mitchell
Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli.
The Journal of experimental medicine 1995;182(5):1469-79.
1995: E F Bernstein; P D Smith; G F Thomas; H Xie; James B Mitchell; E Glatstein; Angelo Russo
A diffusing sphere which delivers homogeneous laser light for use in photodynamic therapy.
Journal of dermatological science 1995;9(3):195-202.
1995: P A Johnstone; William DeGraff; James B Mitchell
Protection from radiation-induced chromosomal aberrations by the nitroxide Tempol.
Cancer 1995;75(9):2323-7.
1995: Stephen M Hahn; D L Lepinski; Anne M DeLuca; James B Mitchell; Terry Pellmar
Neurophysiological consequences of nitroxide antioxidants.
Canadian journal of physiology and pharmacology 1995;73(3):399-403.
1995: John A Cook; James B Mitchell
Measurement of thiols in cell populations from tumor and normal tissue.
Methods in enzymology 1995;251():203-12.
1994: Laurie L Herscher; Murali K Cherukuri; John A Cook; C Norman Coleman; J E Biaglow; S W Tuttle; Frank J Gonzalez; James B Mitchell
Protection against SR 4233 (Tirapazamine) aerobic cytotoxicity by the metal chelators desferrioxamine and tiron.
International journal of radiation oncology, biology, physics 1994;30(4):879-85.
1994: F J Sullivan; Laurie L Herscher; John A Cook; J Smith; Seth M Steinberg; AH Epstein; Edward H Oldfield; T E Goffman; T J Kinsella; James B Mitchell
National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma.
International journal of radiation oncology, biology, physics 1994;30(3):583-90.
1994: William DeGraff; Stephen M Hahn; James B Mitchell; Murali K Cherukuri
Free radical modes of cytotoxicity of adriamycin and streptonigrin.
Biochemical pharmacology 1994;48(7):1427-35.
1994: J Liebmann; Anne M DeLuca; Deborah Coffin; L K Keefer; David Venzon; David A Wink; James B Mitchell
In vivo radiation protection by nitric oxide modulation.
Cancer research 1994;54(13):3365-8.
1994: J Liebmann; John A Cook; J Fisher; D Teague; James B Mitchell
Changes in radiation survival curve parameters in human tumor and rodent cells exposed to paclitaxel (Taxol).
International journal of radiation oncology, biology, physics 1994;29(3):559-64.
1994: J Liebmann; John A Cook; D Teague; J Fisher; James B Mitchell
Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).
Anti-cancer drugs 1994;5(3):287-92.
1994: Stephen W Tuttle; L Hazard; Cameron J Koch; James B Mitchell; C Norman Coleman; John E Biaglow
Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air.
International journal of radiation oncology, biology, physics 1994;29(2):357-62.
1994: Stephen M Hahn; Murali K Cherukuri; Amram Samuni; William DeGraff; D O Cuscela; P Johnstone; James B Mitchell
Potential use of nitroxides in radiation oncology.
Cancer research 1994;54(7 Suppl):2006s-2010s.
1994: J Liebmann; John A Cook; J Fisher; D Teague; James B Mitchell
In vitro studies of Taxol as a radiation sensitizer in human tumor cells.
Journal of the National Cancer Institute 1994;86(6):441-6.
1994: J Liebmann; Anne M DeLuca; A Epstein; S M Steinberg; G Morstyn; James B Mitchell
Protection from lethal irradiation by the combination of stem cell factor and tempol.
Radiation research 1994;137(3):400-4.
1994: J Liebmann; J Bourg; Murali K Cherukuri; J Glass; John A Cook; James B Mitchell
Pharmacokinetic properties of nitroxide-labeled albumin in mice.
Life sciences 1994;54(26):PL503-9.
1994: J Liebmann; John A Cook; C Lipschultz; D Teague; J Fisher; James B Mitchell
The influence of Cremophor EL on the cell cycle effects of paclitaxel (Taxol) in human tumor cell lines.
Cancer chemotherapy and pharmacology 1994;33(4):331-9.
1994: Stephen M Hahn; Murali K Cherukuri; James B Mitchell
New directions for free radical cancer research and medical applications.
Advances in experimental medicine and biology 1994;366():241-51.
1993: James B Mitchell; David A Wink; William DeGraff; Janet Gamson; L K Keefer; Murali K Cherukuri
Hypoxic mammalian cell radiosensitization by nitric oxide.
Cancer research 1993;53(24):5845-8.
1993: J E Liebmann; John A Cook; C Lipschultz; D Teague; J Fisher; James B Mitchell
Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines.
British journal of cancer 1993;68(6):1104-9.
1993: Stephen M Hahn; J E Liebmann; J Cook; J Fisher; Barry Goldspiel; David Venzon; James B Mitchell; D Kaufman
Taxol in combination with doxorubicin or etoposide. Possible antagonism in vitro.
Cancer 1993;72(9):2705-11.
1993: J E Liebmann; Stephen M Hahn; John A Cook; C Lipschultz; James B Mitchell; D C Kaufman
Glutathione depletion by L-buthionine sulfoximine antagonizes taxol cytotoxicity.
Cancer research 1993;53(9):2066-70.
1993: H W Pogrebniak; W Matthews; C Black; Angelo Russo; James B Mitchell; P Smith; J A Roth; Harvey I Pass
Targetted phototherapy with sensitizer-monoclonal antibody conjugate and light.
Surgical oncology 1993;2(1):31-42.
1992: William DeGraff; Murali K Cherukuri; D Kaufman; James B Mitchell
Nitroxide-mediated protection against X-ray- and neocarzinostatin-induced DNA damage.
Free radical biology & medicine 1992;13(5):479-87.
1992: Stephen M Hahn; L Wilson; Murali K Cherukuri; J Liebmann; William DeGraff; Janet Gamson; Amram Samuni; David Venzon; James B Mitchell
Identification of nitroxide radioprotectors.
Radiation research 1992;132(1):87-93.
1992: H W Pogrebniak; Maria J Merino; Stephen M Hahn; James B Mitchell; Harvey I Pass
Spin trap salvage from endotoxemia: the role of cytokine down-regulation.
Surgery 1992;112(2):130-9; discussion 138-9.
1992: Murali K Cherukuri; D A Grahame; Amram Samuni; James B Mitchell; Angelo Russo
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5537-41.
1992: Stephen M Hahn; Z Tochner; Murali K Cherukuri; J Glass; L Wilson; Amram Samuni; M Sprague; David Venzon; E Glatstein; James B Mitchell
Tempol, a stable free radical, is a novel murine radiation protector.
Cancer research 1992;52(7):1750-3.
1992: Murali K Cherukuri; J E Liebmann; D Kaufman; William DeGraff; Stephen M Hahn; T McMurry; James B Mitchell; Angelo Russo
The catecholic metal sequestering agent 1,2-dihydroxybenzene-3,5-disulfonate confers protection against oxidative cell damage.
Archives of biochemistry and biophysics 1992;294(1):98-106.
1992: John A Cook; J Glass; R Lebovics; H Bobo; Harvey I Pass; T F DeLaney; Edward H Oldfield; James B Mitchell; E Glatstein; T E Goffman
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
Cancer research 1992;52(3):719-25.
1992: T E Goffman; L J Dachowski; H Bobo; Edward H Oldfield; Seth M Steinberg; J Cook; James B Mitchell; D Katz; R Smith; E Glatstein
Long-term follow-up on National Cancer Institute Phase I/II study of glioblastoma multiforme treated with iododeoxyuridine and hyperfractionated irradiation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(2):264-8.
1992: James B Mitchell; C Norman Coleman
Biochemical modification of therapeutic response.
International journal of radiation oncology, biology, physics 1992;22(3):483-4.
1992: T Goffman; D Cuscela; J Glass; S Hahn; Murali K Cherukuri; G Lupton; James B Mitchell
Topical application of nitroxide protects radiation-induced alopecia in guinea pigs.
International journal of radiation oncology, biology, physics 1992;22(4):803-6.
1992: Stephen W Tuttle; Marie E Varnes; James B Mitchell; John E Biaglow
Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity.
International journal of radiation oncology, biology, physics 1992;22(4):671-5.
1992: John E Biaglow; James B Mitchell; Kathryn D Held
The importance of peroxide and superoxide in the X-ray response.
International journal of radiation oncology, biology, physics 1992;22(4):665-9.
1992: William DeGraff; Murali K Cherukuri; Angelo Russo; James B Mitchell
Antimutagenicity of a low molecular weight superoxide dismutase mimic against oxidative mutagens.
Environmental and molecular mutagenesis 1992;19(1):21-6.
1991: Murali K Cherukuri; William DeGraff; S Tamura; Frank J Gonzalez; Amram Samuni; Angelo Russo; James B Mitchell
Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells.
Cancer research 1991;51(24):6622-8.
1991: T F DeLaney; P D Smith; G F Thomas; Z A Tochner; W F Sindelar; Harvey I Pass; F S Harrington; Robert F Bonner; James B Mitchell
A light-diffusing device for intraoperative photodynamic therapy in the peritoneal or pleural cavity.
Journal of clinical laser medicine & surgery 1991;9(5):361-6.
1991: James B Mitchell; E Glatstein
Radiation oncology: past achievements and ongoing controversies.
Cancer research 1991;51(18 Suppl):5065s-5073s.
1991: John A Cook; Harvey I Pass; S N Iype; N Friedman; William DeGraff; Angelo Russo; James B Mitchell
Cellular glutathione and thiol measurements from surgically resected human lung tumor and normal lung tissue.
Cancer research 1991;51(16):4287-94.
1991: James B Mitchell; William DeGraff; D Kaufman; Murali K Cherukuri; Amram Samuni; E Finkelstein; M S Ahn; Stephen M Hahn; Janet Gamson; Angelo Russo
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol.
Archives of biochemistry and biophysics 1991;289(1):62-70.
1991: Stephen M Hahn; Murali K Cherukuri; Amram Samuni; James B Mitchell; Angelo Russo
Mn(III)-desferrioxamine superoxide dismutase-mimic: alternative modes of action.
Archives of biochemistry and biophysics 1991;288(1):215-9.
1991: E F Bernstein; J M Glass; William DeGraff; R Schlegel; C Black; J M Fisher; S N Cook; E Glatstein; Angelo Russo; James B Mitchell
In vitro photodynamic treatment of normal and human papilloma virus-transfected keratinocytes with photofrin II and red light.
Archives of dermatology 1991;127(5):683-7.
1991: Amram Samuni; D Winkelsberg; A Pinson; Stephen M Hahn; James B Mitchell; Angelo Russo
Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage.
The Journal of clinical investigation 1991;87(5):1526-30.
1991: John A Cook; S N Iype; James B Mitchell
Differential specificity of monochlorobimane for isozymes of human and rodent glutathione S-transferases.
Cancer research 1991;51(6):1606-12.
1991: Amram Samuni; D Godinger; J Aronovitch; Angelo Russo; James B Mitchell
Nitroxides block DNA scission and protect cells from oxidative damage.
Biochemistry 1991;30(2):555-61.
1991: Z Tochner; James B Mitchell; H J Hoekstra; P Smith; Anne M DeLuca; M Barnes; F Harrington; M Manyak; D Russo; Angelo Russo
Photodynamic therapy of the canine peritoneum: normal tissue response to intraperitoneal and intravenous photofrin followed by 630 nm light.
Lasers in surgery and medicine 1991;11(2):158-64.
1991: Amram Samuni; James B Mitchell; William DeGraff; Murali K Cherukuri; U Samuni; Angelo Russo
Nitroxide SOD-mimics: modes of action.
Free radical research communications 1991;12-13 Pt 1():187-94.
1990: T E Goffman; A Raubitschek; James B Mitchell; E Glatstein
The emerging biology of modern radiation oncology.
Cancer research 1990;50(24):7735-44.
1990: E F Bernstein; G F Thomas; P D Smith; James B Mitchell; E Glatstein; G R Kantor; R L Spielvogel; S C Maiese; Angelo Russo
Response of black and white guinea pig skin to photodynamic treatment using 514-nm light and dihematoporphyrin ether.
Archives of dermatology 1990;126(10):1303-7.
1990: R R Perry; W Matthews; James B Mitchell; Angelo Russo; S Evans; Harvey I Pass
Sensitivity of different human lung cancer histologies to photodynamic therapy.
Cancer research 1990;50(14):4272-6.
1990: James B Mitchell; Amram Samuni; Murali K Cherukuri; William DeGraff; M S Ahn; U Samuni; Angelo Russo
Biologically active metal-independent superoxide dismutase mimics.
Biochemistry 1990;29(11):2802-7.
1990: Z Tochner; M Barnes; James B Mitchell; K Orr; E Glatstein; A Russo
Protection by indomethacin against acute radiation esophagitis.
Digestion 1990;47(2):81-7.
1990: Amram Samuni; A Min; Murali K Cherukuri; James B Mitchell; Angelo Russo
SOD-like activity of 5-membered ring nitroxide spin labels.
Advances in experimental medicine and biology 1990;264():85-92.
1990: Amram Samuni; Murali K Cherukuri; James B Mitchell; C R Collins; Angelo Russo
Superoxide reaction with nitroxides.
Free radical research communications 1990;9(3-6):241-9.
1990: William DeGraff; Angelo Russo; N Friedman; James B Mitchell
Misonidazole hypoxic cytotoxicity and chemosensitization in two cell lines with different intracellular glutathione levels.
European journal of cancer (Oxford, England : 1990) 1990;26(1):17-20.
1989: James B Mitchell; Angelo Russo; John A Cook; K L Straus; E Glatstein
Radiobiology and clinical application of halogenated pyrimidine radiosensitizers.
International journal of radiation biology 1989;56(5):827-36.
1989: A E Alegria; Amram Samuni; James B Mitchell; Péter Riesz; Angelo Russo
Free radicals induced by adriamycin-sensitive and adriamycin-resistant cells: a spin-trapping study.
Biochemistry 1989;28(21):8653-8.
1989: John A Cook; James B Mitchell
Viability measurements in mammalian cell systems.
Analytical biochemistry 1989;179(1):1-7.
1989: John A Cook; Harvey I Pass; Angelo Russo; S Iype; James B Mitchell
Use of monochlorobimane for glutathione measurements in hamster and human tumor cell lines.
International journal of radiation oncology, biology, physics 1989;16(5):1321-4.
1989: James B Mitchell; John A Cook; William DeGraff; E Glatstein; Angelo Russo
Glutathione modulation in cancer treatment: will it work?
International journal of radiation oncology, biology, physics 1989;16(5):1289-95.
1989: T L Phillips; James B Mitchell; William DeGraff; Angelo Russo; N Albright; R Rajpal
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels.
International journal of radiation oncology, biology, physics 1989;16(5):1335-9.
1989: William DeGraff; Angelo Russo; Janet Gamson; James B Mitchell
Evaluation of nitroimidazole hypoxic cell radiosensitizers in a human tumor cell line high in intracellular glutathione.
International journal of radiation oncology, biology, physics 1989;16(4):1021-4.
1989: W Matthews; J Cook; James B Mitchell; R R Perry; S Evans; Harvey I Pass
In vitro photodynamic therapy of human lung cancer: investigation of dose-rate effects.
Cancer research 1989;49(7):1718-21.
1989: R W Atcher; Angelo Russo; William DeGraff; M Moore; D J Grdina; James B Mitchell
Halogenated pyrimidines as radiosensitizers for high-LET radiation.
Radiation research 1989;117(2):351-5.
1988: T Kondo; Janet Gamson; James B Mitchell; Péter Riesz
Free radical formation and cell lysis induced by ultrasound in the presence of different rare gases.
International journal of radiation biology 1988;54(6):955-62.
1988: James B Mitchell
Potential applicability of nonclonogenic measurements to clinical oncology.
Radiation research 1988;114(3):401-14.
1988: S H Kurtzman; A Russo; James B Mitchell; William DeGraff; W F Sindelar; Martin W Brechbiel; Otto A Gansow; A M Friedman; J J Hines; Janet Gamson
212Bismuth linked to an antipancreatic carcinoma antibody: model for alpha-particle-emitter radioimmunotherapy.
Journal of the National Cancer Institute 1988;80(6):449-52.
1988: James B Mitchell; Janet Gamson; Angelo Russo; N Friedman; William DeGraff; J Carmichael; E Glatstein
Chinese hamster pleiotropic multidrug-resistant cells are not radioresistant.
NCI monographs : a publication of the National Cancer Institute 1988;(6):187-91.
1987: James B Mitchell; Angelo Russo
The role of glutathione in radiation and drug induced cytotoxicity.
The British journal of cancer. Supplement 1987;8():96-104.
1986: Angelo Russo; J Carmichael; N Friedman; W DeGraff; Z Tochner; E Glatstein; James B Mitchell
The roles of intracellular glutathione in antineoplastic chemotherapy.
International journal of radiation oncology, biology, physics 1986;12(8):1347-54.
1986: J Carmichael; N Friedman; Z Tochner; D J Adams; C R Wolf; James B Mitchell; Angelo Russo
Inhibition of the protective effect of cyclophosphamide by pre-treatment with buthionine sulfoximine.
International journal of radiation oncology, biology, physics 1986;12(7):1191-3.
1986: Angelo Russo; Z Tochner; T Phillips; J Carmichael; W DeGraff; N Friedman; J Fisher; James B Mitchell
In vivo modulation of glutathione by buthionine sulfoximine: effect on marrow response to melphalan.
International journal of radiation oncology, biology, physics 1986;12(7):1187-9.
1986: Z Tochner; James B Mitchell; P Smith; F Harrington; E Glatstein; D Russo; Angelo Russo
Photodynamic therapy of ascites tumours within the peritoneal cavity.
British journal of cancer 1986;53(6):733-6.
1986: Angelo Russo; W DeGraff; N Friedman; James B Mitchell
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Cancer research 1986;46(6):2845-8.
1985: Angelo Russo; James B Mitchell; William DeGraff; N Friedman; Janet Gamson
Depletion of cellular glutathione by exogenous spermine in V79 cells: implications for spermine-induced hyperthermic sensitization.
Cancer research 1985;45(10):4910-4.
1985: Angelo Russo; James B Mitchell; E Finkelstein; William DeGraff; I J Spiro; Janet Gamson
The effects of cellular glutathione elevation on the oxygen enhancement ratio.
Radiation research 1985;103(2):232-9.
1985: Z Tochner; James B Mitchell; F S Harrington; P Smith; D T Russo; Angelo Russo
Treatment of murine intraperitoneal ovarian ascitic tumor with hematoporphyrin derivative and laser light.
Cancer research 1985;45(7):2983-7.