James Mitchell

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Matsumoto Shingo; Yasui Hironobu; Batra Sonny; Kinoshita Yuichi; Bernardo Marcelino; Munasinghe Jeeva P; Utsumi Hideo; Choudhuri Rajani; Devasahayam Nallathamby; Subramanian Sankaran; Mitchell James B; Krishna Murali C
Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI.
Hyodo Fuminori; Chandramouli Gadisetti V R; Matsumoto Shingo; Matsumoto Ken-Ichiro; Mitchell James B; Krishna Murali C; Munasinghe Jeeva P
Estimation of tumor microvessel density by MRI using a blood pool contrast agent.
Ishii Hisanari; Choudhuri Rajani; Mathias Askale; Sowers Anastasia L; Flanders Kathleen C; Cook John A; Mitchell James B
Halofuginone mediated protection against radiation-induced leg contracture.

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All Publications

2009: Matsumoto Shingo; Yasui Hironobu; Batra Sonny; Kinoshita Yuichi; Bernardo Marcelino; Munasinghe Jeeva P; Utsumi Hideo; Choudhuri Rajani; Devasahayam Nallathamby; Subramanian Sankaran; Mitchell James B; Krishna Murali C
Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(42):17898-903.
2009: Hyodo Fuminori; Chandramouli Gadisetti V R; Matsumoto Shingo; Matsumoto Ken-Ichiro; Mitchell James B; Krishna Murali C; Munasinghe Jeeva P
Estimation of tumor microvessel density by MRI using a blood pool contrast agent.
International journal of oncology 2009;35(4):797-804.
2009: Ishii Hisanari; Choudhuri Rajani; Mathias Askale; Sowers Anastasia L; Flanders Kathleen C; Cook John A; Mitchell James B
Halofuginone mediated protection against radiation-induced leg contracture.
International journal of oncology 2009;35(2):315-9.
2009: Samuni Yuval; Flores-Santana Wilmarie; Krishna Murali C; Mitchell James B; Wink David A
The inhibitors of histone deacetylase suberoylanilide hydroxamate and trichostatin A release nitric oxide upon oxidation.
Free radical biology & medicine 2009;47(4):419-23.
2009: Matsumoto Ken-Ichiro; Okajo Aya; Nagata Katsura; Degraff William G; Nyui Minako; Ueno Megumi; Nakanishi Ikuo; Ozawa Toshihiko; Mitchell James B; Krishna Murali C; Yamamoto Haruhiko; Endo Kazutoyo; Anzai Kazunori
Detection of free radical reactions in an aqueous sample induced by low linear-energy-transfer irradiation.
Biological & pharmaceutical bulletin 2009;32(4):542-7.
2009: Hyodo Fuminori; Matsumoto Shingo; Devasahayam Nallathamby; Dharmaraj Christopher; Subramanian Sankaran; Mitchell James B; Krishna Murali C
Pulsed EPR imaging of nitroxides in mice.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2009;197(2):181-5.
2009: Dharmaraj Christopher D; Thadikonda Kishan; Fletcher Anthony R; Doan Phuc N; Devasahayam Nallathamby; Matsumoto Shingo; Johnson Calvin A; Cook John A; Mitchell James B; Subramanian Sankaran; Krishna Murali C
Reconstruction for Time-Domain In Vivo EPR 3D Multigradient Oximetric Imaging-A Parallel Processing Perspective.
International journal of biomedical imaging 2009;2009():528639.
2009: Simone Nicole L; Soule Benjamin P; Ly David; Saleh Anthony D; Savage Jason E; Degraff William; Cook John; Harris Curtis C; Gius David; Mitchell James B
Ionizing radiation-induced oxidative stress alters miRNA expression.
PloS one 2009;4(7):e6377.
2008: Palayoor Sanjeewani T; Mitchell James B; Cerna David; Degraff William; John-Aryankalayil Molykutty; Coleman C Norman
PX-478, an inhibitor of hypoxia-inducible factor-1alpha, enhances radiosensitivity of prostate carcinoma cells.
International journal of cancer. Journal international du cancer 2008;123(10):2430-7.
2008: Hyodo Fuminori; Soule Benjamin P; Matsumoto Ken-Ichiro; Matusmoto Shingo; Cook John A; Hyodo Emi; Sowers Anastasia L; Krishna Murali C; Mitchell James B
Assessment of tissue redox status using metabolic responsive contrast agents and magnetic resonance imaging.
The Journal of pharmacy and pharmacology 2008;60(8):1049-60.
2008: Flanders Kathleen C; Ho Benjamin M; Arany Praveen R; Stuelten Christina; Mamura Mizuko; Paterniti Miya Okada; Sowers Anastasia; Mitchell James B; Roberts Anita B
Absence of Smad3 induces neutrophil migration after cutaneous irradiation: possible contribution to subsequent radioprotection.
The American journal of pathology 2008;173(1):68-76.
2008: Hyodo Fuminori; Chuang Kai-Hsiang; Goloshevsky Artem G; Sulima Agnieszka; Griffiths Gary L; Mitchell James B; Koretsky Alan P; Krishna Murali C
Brain redox imaging using blood-brain barrier-permeable nitroxide MRI contrast agent.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(6):1165-74.
2008: Matsumoto Shingo; Hyodo Fuminori; Subramanian Sankaran; Devasahayam Nallathamby; Munasinghe Jeeva; Hyodo Emi; Gadisetti Chandramouli; Cook John A; Mitchell James B; Krishna Murali C
Low-field paramagnetic resonance imaging of tumor oxygenation and glycolytic activity in mice.
The Journal of clinical investigation 2008;118(5):1965-73.
2008: Matsumoto Shingo; Espey Michael Graham; Utsumi Hideo; Devasahayam Nallathamby; Matsumoto Ken-Ichiro; Matsumoto Atsuko; Hirata Hiroshi; Wink David A; Kuppusamy Periannan; Subramanian Sankaran; Mitchell James B; Krishna Murali C
Dynamic monitoring of localized tumor oxygenation changes using RF pulsed electron paramagnetic resonance in conscious mice.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2008;59(3):619-25.
2008: Guo Zhanjun; Tsai Mong-Hsun; Shiao Yih-Horng; Chen Li-Han; Wei Mei-Ling; Lv Xing; Gius David; Little John B; Mitchell James B; Chuang Eric Y
DNA (cytosine-5)-methyltransferase 1 as a mediator of mutant p53-determined p16(ink4A) down-regulation.
Journal of biomedical science 2008;15(2):163-8.
2008: Hyodo F; Subramanian S; Devasahayam N; Murugesan R; Matsumoto K; Mitchell J B; Krishna M C
Evaluation of sub-microsecond recovery resonators for in vivo electron paramagnetic resonance imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;190(2):248-54.
2008: Hyodo Fuminori; Murugesan Ramachandran; Matsumoto Ken-ichiro; Hyodo Emi; Subramanian Sankaran; Mitchell James B; Krishna Murali C
Monitoring redox-sensitive paramagnetic contrast agent by EPRI, OMRI and MRI.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2008;190(1):105-12.
2007: Cotrim Ana P; Sowers Anastasia; Mitchell James B; Baum Bruce J
Prevention of irradiation-induced salivary hypofunction by microvessel protection in mouse salivary glands.
Molecular therapy : the journal of the American Society of Gene Therapy 2007;15(12):2101-6.
2007: Hama Yukihiro; Matsumoto Ken-Ichiro; Murugesan Ramachandran; Subramanian Sankaran; Devasahayam Nallathamby; Koscielniak Janusz W; Hyodo Fuminori; Cook John A; Mitchell James B; Krishna Murali C
Continuous wave EPR oximetric imaging at 300 MHz using radiofrequency power saturation effects.
Antioxidants & redox signaling 2007;9(10):1709-16.
2007: Soule Benjamin P; Hyodo Fuminori; Matsumoto Ken-Ichiro; Simone Nicole L; Cook John A; Krishna Murali C; Mitchell James B
Therapeutic and clinical applications of nitroxide compounds.
Antioxidants & redox signaling 2007;9(10):1731-43.
2007: Arany Praveen R; Flanders Kathleen C; DeGraff William; Cook John; Mitchell James B; Roberts Anita B
Absence of Smad3 confers radioprotection through modulation of ERK-MAPK in primary dermal fibroblasts.
Journal of dermatological science 2007;48(1):35-42.
2007: Soule Benjamin P; Brown Jared M; Kushnir-Sukhov Nataliya M; Simone Nicole L; Mitchell James B; Metcalfe Dean D
Effects of gamma radiation on FcepsilonRI and TLR-mediated mast cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(5):3276-86.
2007: Cotrim Ana P; Hyodo Fuminori; Matsumoto Ken-Ichiro; Sowers Anastasia L; Cook John A; Baum Bruce J; Krishna Murali C; Mitchell James B
Differential radiation protection of salivary glands versus tumor by Tempol with accompanying tissue assessment of Tempol by magnetic resonance imaging.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(16):4928-33.
2007: Matsumoto Ken-ichiro; Subramanian Sankaran; Murugesan Ramachandran; Mitchell James B; Krishna Murali C
Spatially resolved biologic information from in vivo EPRI, OMRI, and MRI.
Antioxidants & redox signaling 2007;9(8):1125-41.
2007: Soule Benjamin P; Hyodo Fuminori; Matsumoto Ken-Ichiro; Simone Nicole L; Cook John A; Krishna Murali C; Mitchell James B
The chemistry and biology of nitroxide compounds.
Free radical biology & medicine 2007;42(11):1632-50.
2007: Tsai Mong-Hsun; Cook John A; Chandramouli Gadisetti V R; DeGraff William; Yan Hailing; Zhao Shuping; Coleman C Norman; Mitchell James B; Chuang Eric Y
Gene expression profiling of breast, prostate, and glioma cells following single versus fractionated doses of radiation.
Cancer research 2007;67(8):3845-52.
2007: Devasahayam Nallathamby; Subramanian Sankaran; Murugesan Ramachandran; Hyodo Fuminori; Matsumoto Ken-Ichiro; Mitchell James B; Krishna Murali C
Strategies for improved temporal and spectral resolution in in vivo oximetric imaging using time-domain EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2007;57(4):776-83.
2007: Matsumoto Ken-Ichiro; Szajek Lawrence; Krishna Murali C; Cook John A; Seidel Jurgen; Grimes Kelly; Carson Joann; Sowers Anastasia L; English Sean; Green Michael V; Bacharach Stephen L; Eckelman William C; Mitchell James B
The influence of tumor oxygenation on hypoxia imaging in murine squamous cell carcinoma using [64Cu]Cu-ATSM or [18F]Fluoromisonidazole positron emission tomography.
International journal of oncology 2007;30(4):873-81.
2007: Simone Nicole L; Soule Benjamin P; Gerber Lynn; Augustine Elizabeth; Smith Sharon; Altemus Rosemary M; Mitchell James B; Camphausen Kevin A
Oral Pirfenidone in patients with chronic fibrosis resulting from radiotherapy: a pilot study.
Radiation oncology (London, England) 2007;2():19.
2006: Hyodo Fuminori; Matsumoto Ken-Ichiro; Matsumoto Atsuko; Mitchell James B; Krishna Murali C
Probing the intracellular redox status of tumors with magnetic resonance imaging and redox-sensitive contrast agents.
Cancer research 2006;66(20):9921-8.
2006: Thomas Douglas D; Ridnour Lisa A; Espey Michael Graham; Donzelli Sonia; Ambs Stefan; Hussain S Perwez; Harris Curtis C; DeGraff William; Roberts David D; Mitchell James B; Wink David A
Superoxide fluxes limit nitric oxide-induced signaling.
The Journal of biological chemistry 2006;281(36):25984-93.
2006: Okajo Aya; Matsumoto Ken-ichiro; Mitchell James B; Krishna Murali C; Endo Kazutoyo
Competition of nitroxyl contrast agents as an in vivo tissue redox probe: comparison of pharmacokinetics by the bile flow monitoring (BFM) and blood circulating monitoring (BCM) methods using X-band EPR and simulation of decay profiles.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(2):422-31.
2006: Matsumoto Ken-ichiro; Bernardo Marcelino; Subramanian Sankaran; Choyke Peter; Mitchell James B; Krishna Murali C; Lizak Martin J
MR assessment of changes of tumor in response to hyperbaric oxygen treatment.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;56(2):240-6.
2006: Baum Bruce J; Zheng Changyu; Cotrim Ana P; Goldsmith Corinne M; Atkinson Jane C; Brahim Jaime S; Chiorini John A; Voutetakis Antonis; Leakan Rose Anne; Van Waes Carter; Mitchell James B; Delporte Christine; Wang Songlin; Kaminsky Stephen M; Illei Gabor G
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.
Biochimica et biophysica acta 2006;1758(8):1071-7.
2006: Cook John A; Chuang Eric Y; Tsai Mong-Hsun; Coffin Debbie; Degraff William; Sowers Anastasia L; Mitchell James B
Radiation-induced changes in gene-expression profiles for the SCC VII tumor cells grown in vitro and in vivo.
Antioxidants & redox signaling 2006;8(7-8):1263-72.
2006: Matsumoto Ken-ichiro; Subramanian Sankaran; Devasahayam Nallathamby; Aravalluvan Thirumaran; Murugesan Ramachandran; Cook John A; Mitchell James B; Krishna Murali C
Electron paramagnetic resonance imaging of tumor hypoxia: enhanced spatial and temporal resolution for in vivo pO2 determination.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2006;55(5):1157-63.
2006: Matsumoto Ken-Ichiro; Hyodo Fuminori; Matsumoto Atsuko; Koretsky Alan P; Sowers Anastasia L; Mitchell James B; Krishna Murali C
High-resolution mapping of tumor redox status by magnetic resonance imaging using nitroxides as redox-sensitive contrast agents.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(8):2455-62.
2006: Chuang Eric Y; Chen Xi; Tsai Mong-Hsun; Yan Hailing; Li Chuan-Yuan; Mitchell James B; Nagasawa Hatsumi; Wilson Paul F; Peng Yuanlin; Fitzek Markus M; Bedford Joel S; Little John B
Abnormal gene expression profiles in unaffected parents of patients with hereditary-type retinoblastoma.
Cancer research 2006;66(7):3428-33.
2006: Tsai M-H; Chen X; Chandramouli G V R; Chen Y; Yan H; Zhao S; Keng P; Liber H L; Coleman C N; Mitchell J B; Chuang E Y
Transcriptional responses to ionizing radiation reveal that p53R2 protects against radiation-induced mutagenesis in human lymphoblastoid cells.
Oncogene 2006;25(4):622-32.
2006: Patel Kinjal; Chen Yifan; Dennehy Kathryn; Blau Jonathan; Connors Stephanie; Mendonca Margarida; Tarpey Margaret; Krishna Murali; Mitchell James B; Welch William J; Wilcox Christopher S
Acute antihypertensive action of nitroxides in the spontaneously hypertensive rat.
American journal of physiology. Regulatory, integrative and comparative physiology 2006;290(1):R37-43.
2006: Chan Linda W; Hapdey Sebastien; English Sean; Seidel Jurgen; Carson Joann; Sowers Anastasia L; Krishna Murali C; Green Michael V; Mitchell James B; Bacharach Stephen L
The influence of tumor oxygenation on (18)F-FDG (fluorine-18 deoxyglucose) uptake: a mouse study using positron emission tomography (PET).
Radiation oncology (London, England) 2006;1():3.
2005: Sostaric Joe Z; Miyoshi Norio; Riesz Peter; DeGraff William G; Mitchell James B
n-Alkyl glucopyranosides completely inhibit ultrasound-induced cytolysis.
Free radical biology & medicine 2005;39(12):1539-48.
2005: Matsumoto Atsuko; Matsumoto Shingo; Sowers Anastasia L; Koscielniak Janusz W; Trigg Nancy J; Kuppusamy Periannan; Mitchell James B; Subramanian Sankaran; Krishna Murali C; Matsumoto Ken-Ichiro
Absolute oxygen tension (pO(2)) in murine fatty and muscle tissue as determined by EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(6):1530-5.
2005: Van Waes Carter; Chang Angela A; Lebowitz Peter F; Druzgal Colleen H; Chen Zhong; Elsayed Yusri A; Sunwoo John B; Rudy Susan F; Morris John C; Mitchell James B; Camphausen Kevin; Gius David; Adams Julian; Sausville Edward A; Conley Barbara A
Inhibition of nuclear factor-kappaB and target genes during combined therapy with proteasome inhibitor bortezomib and reirradiation in patients with recurrent head-and-neck squamous cell carcinoma.
International journal of radiation oncology, biology, physics 2005;63(5):1400-12.
2005: Cotrim Ana P; Sowers Anastasia L; Lodde Beatrijs M; Vitolo Joseph M; Kingman Albert; Russo Angelo; Mitchell James B; Baum Bruce J
Kinetics of tempol for prevention of xerostomia following head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(20):7564-8.
2005: Camphausen Kevin; Citrin Deborah; Krishna Murali C; Mitchell James B
Implications for tumor control during protection of normal tissues with antioxidants.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(24):5455-7.
2005: Muanza Thierry M; Cotrim Ana P; McAuliffe Mathew; Sowers Anastasia L; Baum Bruce J; Cook John A; Feldchtein Felix; Amazeen Paul; Coleman C Norman; Mitchell James B
Evaluation of radiation-induced oral mucositis by optical coherence tomography.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5121-7.
2005: Matsumoto Shingo; Utsumi Hideo; Aravalluvan Thirumaran; Matsumoto Ken-Ichiro; Matsumoto Atsuko; Devasahayam Nallathamby; Sowers Anastasia L; Mitchell James B; Subramanian Sankaran; Krishna Murali C
Influence of proton T1 on oxymetry using Overhauser enhanced magnetic resonance imaging.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2005;54(1):213-7.
2005: Matsumoto Ken-ichiro; Okajo Aya; Kobayashi Takenori; Mitchell James B; Krishna Murali C; Endo Kazutoyo
Estimation of free radical formation by beta-ray irradiation in rat liver.
Journal of biochemical and biophysical methods 2005;63(2):79-90.
2005: Tsai Mong-Hsun; Yan Hailing; Chen Xi; Chandramouli G V R; Zhao Shuping; Coffin Deborah; Coleman C Norman; Mitchell James B; Chuang Eric Y
Evaluation of hybridization conditions for spotted oligonucleotide-based DNA microarrays.
Molecular biotechnology 2005;29(3):221-4.
2005: Suy Simeng; Mitchell James B; Samuni Ayelet; Mueller Susette; Kasid Usha
Nitroxide tempo, a small molecule, induces apoptosis in prostate carcinoma cells and suppresses tumor growth in athymic mice.
Cancer 2005;103(6):1302-13.
2005: Samuni Ayelet M; Kasid Usha; Chuang Eric Y; Suy Simeng; Degraff William; Krishna Murali C; Russo Angelo; Mitchell James B
Effects of hypoxia on radiation-responsive stress-activated protein kinase, p53, and caspase 3 signals in TK6 human lymphoblastoid cells.
Cancer research 2005;65(2):579-86.
2004: Kobayashi Hisataka; Reijnders Koen; English Sean; Yordanov Alexander T; Milenic Diane E; Sowers Anastasia L; Citrin Deborah; Krishna Murali C; Waldmann Thomas A; Mitchell James B; Brechbiel Martin W
Application of a macromolecular contrast agent for detection of alterations of tumor vessel permeability induced by radiation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7712-20.
2004: Mitchell James B; Yamada Kenichi; Devasahayam Nallathamby; Cook John A; Subramanian Sankaran; Krishna Murali C
Novel functional imaging for tissue oxygen concentration and redox status.
The Journal of nutrition 2004;134(11):3210S.
2004: Samuni Ayelet M; DeGraff William; Cook John A; Krishna Murali C; Russo Angelo; Mitchell James B
The effects of antioxidants on radiation-induced apoptosis pathways in TK6 cells.
Free radical biology & medicine 2004;37(10):1648-55.
2004: Gius David; Cui Hengmi; Bradbury C Matthew; Cook John; Smart Deedee K; Zhao Shuping; Young Lynn; Brandenburg Sheri A; Hu Yali; Bisht Kheem S; Ho Allen S; Mattson David; Sun Lunching; Munson Peter J; Chuang Eric Y; Mitchell James B; Feinberg Andrew P
Distinct effects on gene expression of chemical and genetic manipulation of the cancer epigenome revealed by a multimodality approach.
Cancer cell 2004;6(4):361-71.
2004: Matsumoto Ken-Ichiro; English Sean; Yoo John; Yamada Ken-Ichi; Devasahayam Nallathamby; Cook John A; Mitchell James B; Subramanian Sankaran; Krishna Murali C
Pharmacokinetics of a triarylmethyl-type paramagnetic spin probe used in EPR oximetry.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;52(4):885-92.
2004: Loercher Amy; Lee Tin Lap; Ricker Justin L; Howard April; Geoghegen Joel; Chen Zhong; Sunwoo John B; Sitcheran Raquel; Chuang Eric Y; Mitchell James B; Baldwin Albert S; Van Waes Carter
Nuclear factor-kappaB is an important modulator of the altered gene expression profile and malignant phenotype in squamous cell carcinoma.
Cancer research 2004;64(18):6511-23.
2004: Rosenwald Andreas; Chuang Eric Y; Davis R Eric; Wiestner Adrian; Alizadeh Ash A; Arthur Diane C; Mitchell James B; Marti Gerald E; Fowler Daniel H; Wilson Wyndham H; Staudt Louis M
Fludarabine treatment of patients with chronic lymphocytic leukemia induces a p53-dependent gene expression response.
Blood 2004;104(5):1428-34.
2004: Matsumoto Ken-Ichiro; Krishna Murali C; Mitchell James B
Novel pharmacokinetic measurement using electron paramagnetic resonance spectroscopy and simulation of in vivo decay of various nitroxyl spin probes in mouse blood.
The Journal of pharmacology and experimental therapeutics 2004;310(3):1076-83.
2004: Subramanian Sankaran; Matsumoto Ken-Ichiro; Mitchell James B; Krishna Murali C
Radio frequency continuous-wave and time-domain EPR imaging and Overhauser-enhanced magnetic resonance imaging of small animals: instrumental developments and comparison of relative merits for functional imaging.
NMR in biomedicine 2004;17(5):263-94.
2004: Cook John A; Gius David; Wink David A; Krishna Murali C; Russo Angelo; Mitchell James B
Oxidative stress, redox, and the tumor microenvironment.
Seminars in radiation oncology 2004;14(3):259-66.
2004: Samuni Yuval; Gamson Janet; Samuni Ayelet; Yamada Kenichi; Russo Angelo; Krishna Murali C; Mitchell James B
Factors influencing nitroxide reduction and cytotoxicity in vitro.
Antioxidants & redox signaling 2004;6(3):587-95.
2004: Devasahayam N; Murugesan R; Matsumoto K; Mitchell J B; Cook J A; Subramanian S; Krishna M C
Tailored sinc pulses for uniform excitation and artifact-free radio frequency time-domain EPR imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2004;168(1):110-7.
2004: Xavier Sandhya; Piek Ester; Fujii Makiko; Javelaud Delphine; Mauviel Alain; Flanders Kathy C; Samuni Ayelet M; Felici Angelina; Reiss Michael; Yarkoni Shai; Sowers Anastasia; Mitchell James B; Roberts Anita B; Russo Angelo
Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.
The Journal of biological chemistry 2004;279(15):15167-76.
2004: Vitolo Joseph M; Cotrim Ana P; Sowers Anastasia L; Russo Angelo; Wellner Robert B; Pillemer Stanley R; Mitchell James B; Baum Bruce J
The stable nitroxide tempol facilitates salivary gland protection during head and neck irradiation in a mouse model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(5):1807-12.
2004: Reijnders Koen; English Sean J; Krishna Murali C; Cook John A; Sowers Anastasia L; Mitchell James B; Zhang Yantian
Influence of body temperature on the BOLD effect in murine SCC tumors.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2004;51(2):389-93.
2003: Bisht Kheem S; Bradbury C Matthew; Mattson David; Kaushal Aradhana; Sowers Anastasia; Markovina Stephanie; Ortiz Karen L; Sieck Leah K; Isaacs Jennifer S; Brechbiel Martin W; Mitchell James B; Neckers Leonard M; Gius David
Geldanamycin and 17-allylamino-17-demethoxygeldanamycin potentiate the in vitro and in vivo radiation response of cervical tumor cells via the heat shock protein 90-mediated intracellular signaling and cytotoxicity.
Cancer research 2003;63(24):8984-95.
2003: Flanders Kathleen C; Major Christopher D; Arabshahi Alidad; Aburime Ekinadese E; Okada Miya H; Fujii Makiko; Blalock Timothy D; Schultz Gregory S; Sowers Anastasia; Anzano Mario A; Mitchell James B; Russo Angelo; Roberts Anita B
Interference with transforming growth factor-beta/ Smad3 signaling results in accelerated healing of wounds in previously irradiated skin.
The American journal of pathology 2003;163(6):2247-57.
2003: Matsumoto Ken-ichiro; Chandrika Baby; Lohman Joost A B; Mitchell James B; Krishna Murali C; Subramanian Sankaran
Application of continuous-wave EPR spectral-spatial image reconstruction techniques for in vivo oxymetry: comparison of projection reconstruction and constant-time modalities.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2003;50(4):865-74.
2003: Taube Andrew G; Subramanian Sankaran; Murugesan Ramachandran; Devasahayam Nallathamby; Mitchell James B; Krishna Murali C; Cook John A
An application system for automation of constant-time radio frequency electron paramagnetic resonance imaging.
Computer methods and programs in biomedicine 2003;72(2):127-38.
2003: De Graff William G; Myers L S; Mitchell James B; Hahn Stephen M
Protection against Adriamycin cytotoxicity and inhibition of DNA topoisomerase II activity by 3,4-dihydroxybenzoic acid.
International journal of oncology 2003;23(1):159-63.
2003: Kennedy Christopher H; Pass Harvey I; Mitchell James B
Expression of human MutT homologue (hMTH1) protein in primary non-small-cell lung carcinomas and histologically normal surrounding tissue.
Free radical biology & medicine 2003;34(11):1447-57.
2003: Coleman C Norman; Blakely William F; Fike John R; MacVittie Thomas J; Metting Noelle F; Mitchell James B; Moulder John E; Preston R Julian; Seed Thomas M; Stone Helen B; Tofilon Philip J; Wong Rosemary S L
Molecular and cellular biology of moderate-dose (1-10 Gy) radiation and potential mechanisms of radiation protection: report of a workshop at Bethesda, Maryland, December 17-18, 2001.
Radiation research 2003;159(6):812-34.
2003: Samuni Ayelet M; Chuang Eric Y; Krishna Murali C; Stein William; DeGraff William; Russo Angelo; Mitchell James B
Semiquinone radical intermediate in catecholic estrogen-mediated cytotoxicity and mutagenesis: chemoprevention strategies with antioxidants.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(9):5390-5.
2003: Wink David A; Mitchell James B
Nitric oxide and cancer: an introduction.
Free radical biology & medicine 2003;34(8):951-4.
2003: Mitchell James B; Xavier Sandhya; DeLuca Anne M; Sowers Anastasia L; Cook John A; Krishna Murali C; Hahn Stephen M; Russo Angelo
A low molecular weight antioxidant decreases weight and lowers tumor incidence.
Free radical biology & medicine 2003;34(1):93-102.
2003: Stein William; Subramanian S; Mitchell James B; Krishna Murali C
EPR imaging of vascular changes in oxygen in response to carbogen breathing.
Advances in experimental medicine and biology 2003;510():231-6.
2002: Chuang Yao-Yu Eric; Chen Yidong; Gadisetti; Chandramouli V R; Cook John A; Coffin Deborah; Tsai Mong-Hsun; DeGraff William; Yan Hailing; Zhao Shuping; Russo Angelo; Liu Edison T; Mitchell James B
Gene expression after treatment with hydrogen peroxide, menadione, or t-butyl hydroperoxide in breast cancer cells.
Cancer research 2002;62(21):6246-54.
2002: Xavier Sandhya; Yamada Ken-ichi; Samuni Ayelet M; Samuni Amram; DeGraff William; Krishna Murali C; Mitchell James B
Differential protection by nitroxides and hydroxylamines to radiation-induced and metal ion-catalyzed oxidative damage.
Biochimica et biophysica acta 2002;1573(2):109-20.
2002: Poggi Matthew M; Kroog Glenn S; Russo Angelo; Muir Christine; Cook John; Smith Judith; Mitchell James B; Herscher Laurie L
Phase I study of weekly gemcitabine as a radiation sensitizer for unresectable pancreatic cancer.
International journal of radiation oncology, biology, physics 2002;54(3):670-6.
2002: Ilangovan Govindasamy; Li Haiquan; Zweier Jay L; Krishna Murali C; Mitchell James B; Kuppusamy Periannan
In vivo measurement of regional oxygenation and imaging of redox status in RIF-1 murine tumor: effect of carbogen-breathing.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(4):723-30.
2002: Murugesan Ramachandran; English Sean; Reijnders Koen; Yamada Ken-Ichi; Cook John A; Mitchell James B; Subramanian Sankaran; Krishna Murali C
Fluorine electron double resonance imaging for 19F MRI in low magnetic fields.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(3):523-9.
2002: Subramanian Sankaran; Devasahayam Nallathamby; Murugesan Ramachandran; Yamada Kenichi; Cook John; Taube Andrew; Mitchell James B; Lohman Joost A B; Krishna Murali C
Single-point (constant-time) imaging in radiofrequency Fourier transform electron paramagnetic resonance.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;48(2):370-9.
2002: Yamada K-I; Kuppusamy P; English S; Yoo J; Irie A; Subramanian S; Mitchell J B; Krishna M C
Feasibility and assessment of non-invasive in vivo redox status using electron paramagnetic resonance imaging.
Acta radiologica (Stockholm, Sweden : 1987) 2002;43(4):433-40.
2002: Samuni Amram; Goldstein Sara; Russo Angelo; Mitchell James B; Krishna Murali C; Neta Pedatsur
Kinetics and mechanism of hydroxyl radical and OH-adduct radical reactions with nitroxides and with their hydroxylamines.
Journal of the American Chemical Society 2002;124(29):8719-24.
2002: Samuni Ayelet M; Krishna Murali C; DeGraff William; Russo Angelo; Planalp Roy P; Brechbiel Martin W; Mitchell James B
Mechanisms underlying the cytotoxic effects of Tachpyr--a novel metal chelator.
Biochimica et biophysica acta 2002;1571(3):211-8.
2002: Samuni Ayelet M; DeGraff William; Krishna Murali C; Mitchell James B
Nitroxides as antioxidants: Tempol protects against EO9 cytotoxicity.
Molecular and cellular biochemistry 2002;234-235(1-2):327-33.
2002: Miranda Katrina M; Yamada Ken-ichi; Espey Michael G; Thomas Douglas D; DeGraff William; Mitchell James B; Krishna Murali C; Colton Carol A; Wink David A
Further evidence for distinct reactive intermediates from nitroxyl and peroxynitrite: effects of buffer composition on the chemistry of Angeli's salt and synthetic peroxynitrite.
Archives of biochemistry and biophysics 2002;401(2):134-44.
2002: Goldstein Sara; Samuni Amram; Aronovitch Yaacov; Godinger Dina; Russo Angelo; Mitchell James B
Kinetics of paraquat and copper reactions with nitroxides: the effects of nitroxides on the aerobic and anoxic toxicity of paraquat.
Chemical research in toxicology 2002;15(5):686-91.
2002: Yordanov Alexander T; Yamada Ken-ichi; Krishna Murali C; Russo Angelo; Yoo John; English Sean; Mitchell James B; Brechbiel Martin W
Acyl-protected hydroxylamines as spin label generators for EPR brain imaging.
Journal of medicinal chemistry 2002;45(11):2283-8.
2002: Subramanian Sankaran; Yamada Ken-Ichi; Irie Akira; Murugesan Ramachandran; Cook John A; Devasahayam Nallathamby; Van Dam Gootzian M; Mitchell James B; Krishna Murali C
Noninvasive in vivo oximetric imaging by radiofrequency FT EPR.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2002;47(5):1001-8.
2002: Flanders Kathleen C; Sullivan Catherine D; Fujii Makiko; Sowers Anastasia; Anzano Mario A; Arabshahi Alidad; Major Christopher; Deng Chuxia; Russo Angelo; Mitchell James B; Roberts Anita B
Mice lacking Smad3 are protected against cutaneous injury induced by ionizing radiation.
The American journal of pathology 2002;160(3):1057-68.
2002: Mitchell James B; Krishna Murali C
Nitroxides as radiation protectors.
Military medicine 2002;167(2 Suppl):49-50.
2002: Krishna Murali C; English Sean; Yamada Kenichi; Yoo John; Murugesan Ramachandran; Devasahayam Nallathamby; Cook John A; Golman Klaes; Ardenkjaer-Larsen Jan Henrik; Subramanian Sankaran; Mitchell James B
Overhauser enhanced magnetic resonance imaging for tumor oximetry: coregistration of tumor anatomy and tissue oxygen concentration.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2216-21.
2002: Yamada Ken-Ichi; Murugesan Ramachandran; Devasahayam Nallathamby; Cook John A; Mitchell James B; Subramanian Sankaran; Krishna Murali C
Evaluation and comparison of pulsed and continuous wave radiofrequency electron paramagnetic resonance techniques for in vivo detection and imaging of free radicals.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;154(2):287-97.
2002: Kuppusamy Periannan; Li Haiquan; Ilangovan Govindasamy; Cardounel Arturo J; Zweier Jay L; Yamada Kenichi; Krishna Murali C; Mitchell James B
Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels.
Cancer research 2002;62(1):307-12.
2001: Poggi M M; Coleman C N; Mitchell J B
Sensitizers and protectors of radiation and chemotherapy.
Current problems in cancer 2001;25(6):334-411.
2001: Roberts A B; Piek E; Böttinger E P; Ashcroft G; Mitchell J B; Flanders K C
Is Smad3 a major player in signal transduction pathways leading to fibrogenesis?
Chest 2001;120(1 Suppl):43S-47S.
2001: Mitchell J B; Krishna M C; Kuppusamy P; Cook J A; Russo A
Protection against oxidative stress by nitroxides.
Experimental biology and medicine (Maywood, N.J.) 2001;226(7):620-1.
2001: Samuni A M; DeGraff W; Krishna M C; Mitchell J B
Cellular sites of H2O2-induced damage and their protection by nitroxides.
Biochimica et biophysica acta 2001;1525(1-2):70-6.
2001: Ogawa R; Pacelli R; Espey M G; Miranda K M; Friedman N; Kim S M; Cox G; Mitchell J B; Wink D A; Russo A
Comparison of control of Listeria by nitric oxide redox chemistry from murine macrophages and NO donors: insights into listeriocidal activity of oxidative and nitrosative stress.
Free radical biology & medicine 2001;30(3):268-76.
2001: Sunwoo J B; Herscher L L; Kroog G S; Thomas G R; Ondrey F G; Duffey D C; Solomon B I; Boss C; Albert P S; McCullugh L; Rudy S; Muir C; Zhai S; Figg W D; Cook J A; Mitchell J B; Van Waes C
Concurrent paclitaxel and radiation in the treatment of locally advanced head and neck cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(3):800-11.
2001: Samuni A M; Afeworki M; Stein W; Yordanov A T; DeGraff W; Krishna M C; Mitchell J B; Brechbiel M W
Multifunctional antioxidant activity of HBED iron chelator.
Free radical biology & medicine 2001;30(2):170-7.
2001: Krishna M C; Subramanian S; Kuppusamy P; Mitchell J B
Magnetic resonance imaging for in vivo assessment of tissue oxygen concentration.
Seminars in radiation oncology 2001;11(1):58-69.
2000: Kato T; Duffey D C; Ondrey F G; Dong G; Chen Z; Cook J A; Mitchell J B; Van Waes C
Cisplatin and radiation sensitivity in human head and neck squamous carcinomas are independently modulated by glutathione and transcription factor NF-kappaB.
Head & neck 2000;22(8):748-59.
2000: Zhou Q; Fukushima P; DeGraff W; Mitchell J B; Stetler Stevenson M; Ashkenazi A; Steeg P S
Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1.
Cancer research 2000;60(10):2611-5.
2000: Hahn S M; Krishna M C; DeLuca A M; Coffin D; Mitchell J B
Evaluation of the hydroxylamine Tempol-H as an in vivo radioprotector.
Free radical biology & medicine 2000;28(6):953-8.
2000: Afeworki M; van Dam G M; Devasahayam N; Murugesan R; Cook J; Coffin D; Larsen J H; Mitchell J B; Subramanian S; Krishna M C
Three-dimensional whole body imaging of spin probes in mice by time-domain radiofrequency electron paramagnetic resonance.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 2000;43(3):375-82.
2000: Vodovotz Y; Lucia M S; DeLucca A M; Mitchell J B; Kopp J B
Reduced hematopoietic function and enhanced radiosensitivity of transforming growth factor-beta1 transgenic mice.
International journal of cancer. Journal international du cancer 2000;90(1):13-21.
2000: Bernhard E J; Mitchell J B; Deen D; Cardell M; Rosenthal D I; Brown J M
Re-evaluating gadolinium(III) texaphyrin as a radiosensitizing agent.
Cancer research 2000;60(1):86-91.
2000: Devasahayam N; Subramanian S; Murugesan R; Cook J A; Afeworki M; Tschudin R G; Mitchell J B; Krishna M C
Parallel coil resonators for time-domain radiofrequency electron paramagnetic resonance imaging of biological objects.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2000;142(1):168-76.
2000: Mitchell J B; Russo A; Kuppusamy P; Krishna M C
Radiation, radicals, and images.
Annals of the New York Academy of Sciences 2000;899():28-43.
1999: Herscher L L; Cook J A; Pacelli R; Pass H I; Russo A; Mitchell J B
Principles of chemoradiation: theoretical and practical considerations.
Oncology (Williston Park, N.Y.) 1999;13(10 Suppl 5):11-22.
1999: Hahn S M; Sullivan F J; DeLuca A M; Bacher J D; Liebmann J; Krishna M C; Coffin D; Mitchell J B
Hemodynamic effect of the nitroxide superoxide dismutase mimics.
Free radical biology & medicine 1999;27(5-6):529-35.
1999: Subramanian S; Murugesan R; Devasahayam N; Cook J A; Afeworki M; Pohida T; Tschudin R G; Mitchell J B; Krishna M C
High-speed data acquisition system and receiver configurations for time-domain radiofrequency electron paramagnetic resonance spectroscopy and imaging.
Journal of magnetic resonance (San Diego, Calif. : 1997) 1999;137(2):379-88.
1999: Hahn S M; Russo A; Cook J A; Mitchell J B
A multidrug-resistant breast cancer cell line induced by weekly exposure to doxorubicin.
International journal of oncology 1999;14(2):273-9.
1999: Samuni Y; Coffin D; DeLuca A M; DeGraff W G; Venson D J; Ambudkar I; Chevion M; Mitchell J B
The use of Zn-desferrioxamine for radioprotection in mice, tissue culture, and isolated DNA.
Cancer research 1999;59(2):405-9.
1999: Vodovotz Y; Coffin D; DeLuca A M; McKinney L; Cook J A; Wink D; Mitchell J B
Induction of nitric oxide production in infiltrating leukocytes following in vivo irradiation of tumor-bearing mice.
Radiation oncology investigations 1999;7(2):86-97.
1999: Wink D A; Vodovotz Y; Grisham M B; DeGraff W; Cook J C; Pacelli R; Krishna M; Mitchell J B
Antioxidant effects of nitric oxide.
Methods in enzymology 1999;301():413-24.
1998: Hahn S M; DeLuca A M; Coffin D; Krishna C M; Mitchell J B
In vivo radioprotection and effects on blood pressure of the stable free radical nitroxides.
International journal of radiation oncology, biology, physics 1998;42(4):839-42.
1998: Mitchell J B; DeGraff W; Kim S; Cook J A; Gamson J; Christodoulou D; Feelisch M; Wink D A
Redox generation of nitric oxide to radiosensitize hypoxic cells.
International journal of radiation oncology, biology, physics 1998;42(4):795-8.
1998: Wink D A; Mitchell J B
Chemical biology of nitric oxide: Insights into regulatory, cytotoxic, and cytoprotective mechanisms of nitric oxide.
Free radical biology & medicine 1998;25(4-5):434-56.
1998: Krishna M C; Kuppusamy P; Afeworki M; Zweier J L; Cook J A; Subramanian S; Mitchell J B
Development of functional electron paramagnetic resonance imaging.
Breast disease 1998;10(3-4):209-20.
1998: Krishna M C; DeGraff W; Hankovszky O H; Sár C P; Kálai T; Jeko J; Russo A; Mitchell J B; Hideg K
Studies of structure-activity relationship of nitroxide free radicals and their precursors as modifiers against oxidative damage.
Journal of medicinal chemistry 1998;41(18):3477-92.
1998: Wink D A; Vodovotz Y; Cook J A; Krishna M C; Kim S; Coffin D; DeGraff W; Deluca A M; Liebmann J; Mitchell J B
The role of nitric oxide chemistry in cancer treatment.
Biochemistry. Biokhimii?a 1998;63(7):802-9.
1998: Afeworki M; Miller N R; Devasahayam N; Cook J; Mitchell J B; Subramanian S; Krishna M C
Preparation and EPR studies of lithium phthalocyanine radical as an oxymetric probe.
Free radical biology & medicine 1998;25(1):72-8.
1998: Suy S; Mitchell J B; Ehleiter D; Haimovitz-Friedman A; Kasid U
Nitroxides tempol and tempo induce divergent signal transduction pathways in MDA-MB 231 breast cancer cells.
The Journal of biological chemistry 1998;273(28):17871-8.
1998: Kuppusamy P; Afeworki M; Shankar R A; Coffin D; Krishna M C; Hahn S M; Mitchell J B; Zweier J L
In vivo electron paramagnetic resonance imaging of tumor heterogeneity and oxygenation in a murine model.
Cancer research 1998;58(7):1562-8.
1998: Theodossiou C; Cook J A; Fisher J; Teague D; Liebmann J E; Russo A; Mitchell J B
Interaction of gemcitabine with paclitaxel and cisplatin in human tumor cell lines.
International journal of oncology 1998;12(4):825-32.
1998: Wink D A; Feelisch M; Fukuto J; Chistodoulou D; Jourd'heuil D; Grisham M B; Vodovotz Y; Cook J A; Krishna M; DeGraff W G; Kim S; Gamson J; Mitchell J B
The cytotoxicity of nitroxyl: possible implications for the pathophysiological role of NO.
Archives of biochemistry and biophysics 1998;351(1):66-74.
1998: Herscher L L; Hahn S M; Kroog G; Pass H; Temeck B; Goldspiel B; Cook J; Mitchell J B; Liebmann J
Phase I study of paclitaxel as a radiation sensitizer in the treatment of mesothelioma and non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(2):635-41.
1998: Vodovotz Y; Kopp J B; Takeguchi H; Shrivastav S; Coffin D; Lucia M S; Mitchell J B; Webber R; Letterio J; Wink D; Roberts A B
Increased mortality, blunted production of nitric oxide, and increased production of TNF-alpha in endotoxemic TGF-beta1 transgenic mice.
Journal of leukocyte biology 1998;63(1):31-9.
1997: Murugesan R; Cook J A; Devasahayam N; Afeworki M; Subramanian S; Tschudin R; Larsen J A; Mitchell J B; Russo A; Krishna M C
In vivo imaging of a stable paramagnetic probe by pulsed-radiofrequency electron paramagnetic resonance spectroscopy.
Magnetic resonance in medicine : official journal of the Society of Magnetic Resonance in Medicine / Society of Magnetic Resonance in Medicine 1997;38(3):409-14.
1997: Wink D A; Cook J A; Kim S Y; Vodovotz Y; Pacelli R; Krishna M C; Russo A; Mitchell J B; Jourd'heuil D; Miles A M; Grisham M B
Superoxide modulates the oxidation and nitrosation of thiols by nitric oxide-derived reactive intermediates. Chemical aspects involved in the balance between oxidative and nitrosative stress.
The Journal of biological chemistry 1997;272(17):11147-51.
1997: Chen A Y; Okunieff P; Pommier Y; Mitchell J B
Mammalian DNA topoisomerase I mediates the enhancement of radiation cytotoxicity by camptothecin derivatives.
Cancer research 1997;57(8):1529-36.
1997: Wink D A; Cook J A; Christodoulou D; Krishna M C; Pacelli R; Kim S; DeGraff W; Gamson J; Vodovotz Y; Russo A; Mitchell J B
Nitric oxide and some nitric oxide donor compounds enhance the cytotoxicity of cisplatin.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(1):88-94.
1997: Hahn S M; Mitchell J B; Shacter E
Tempol inhibits neutrophil and hydrogen peroxide-mediated DNA damage.
Free radical biology & medicine 1997;23(6):879-84.
1997: Cook J A; Krishna M C; Pacelli R; DeGraff W; Liebmann J; Mitchell J B; Russo A; Wink D A
Nitric oxide enhancement of melphalan-induced cytotoxicity.
British journal of cancer 1997;76(3):325-34.
1997: Twomey P; Taira J; DeGraff W; Mitchell J B; Russo A; Krishna M C; Hankovszky O H; Frank L; Hideg K
Direct evidence for in vivo nitroxide free radical production from a new antiarrhythmic drug by EPR spectroscopy.
Free radical biology & medicine 1997;22(5):909-16.
1997: Hahn S M; Sullivan F J; DeLuca A M; Krishna C M; Wersto N; Venzon D; Russo A; Mitchell J B
Evaluation of tempol radioprotection in a murine tumor model.
Free radical biology & medicine 1997;22(7):1211-6.
1996: Krishna M C; Samuni A; Taira J; Goldstein S; Mitchell J B; Russo A
Stimulation by nitroxides of catalase-like activity of hemeproteins. Kinetics and mechanism.
The Journal of biological chemistry 1996;271(42):26018-25.
1996: Cuscela D; Coffin D; Lupton G P; Cook J A; Krishna M C; Bonner R F; Mitchell J B
Protection from radiation-induced alopecia with topical application of nitroxides: fractionated studies.
The cancer journal from Scientific American 1996;2(5):273-8.
1996: Mitchell J B; Cook J A; Krishna M C; DeGraff W; Gamson J; Fisher J; Christodoulou D; Wink D A
Radiation sensitisation by nitric oxide releasing agents.
The British journal of cancer. Supplement 1996;27():S181-4.
1996: Wink D A; Cook J A; Pacelli R; DeGraff W; Gamson J; Liebmann J; Krishna M C; Mitchell J B
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: a direct correlation between nitric oxide formation and protection.
Archives of biochemistry and biophysics 1996;331(2):241-8.
1996: Cook J A; Kim S Y; Teague D; Krishna M C; Pacelli R; Mitchell J B; Vodovotz Y; Nims R W; Christodoulou D; Miles A M; Grisham M B; Wink D A
Convenient colorimetric and fluorometric assays for S-nitrosothiols.
Analytical biochemistry 1996;238(2):150-8.
1995: Wink D A; Cook J A; Pacelli R; Liebmann J; Krishna M C; Mitchell J B
Nitric oxide (NO) protects against cellular damage by reactive oxygen species.
Toxicology letters 1995;82-83():221-6.
1995: Pacelli R; Wink D A; Cook J A; Krishna M C; DeGraff W; Friedman N; Tsokos M; Samuni A; Mitchell J B
Nitric oxide potentiates hydrogen peroxide-induced killing of Escherichia coli.
The Journal of experimental medicine 1995;182(5):1469-79.
1995: Bernstein E F; Smith P D; Thomas G F; Xie H; Mitchell J B; Glatstein E; Russo A
A diffusing sphere which delivers homogeneous laser light for use in photodynamic therapy.
Journal of dermatological science 1995;9(3):195-202.
1995: Johnstone P A; DeGraff W G; Mitchell J B
Protection from radiation-induced chromosomal aberrations by the nitroxide Tempol.
Cancer 1995;75(9):2323-7.
1995: Hahn S M; Lepinski D L; DeLuca A M; Mitchell J B; Pellmar T C
Neurophysiological consequences of nitroxide antioxidants.
Canadian journal of physiology and pharmacology 1995;73(3):399-403.
1995: Cook J A; Mitchell J B
Measurement of thiols in cell populations from tumor and normal tissue.
Methods in enzymology 1995;251():203-12.
1994: Herscher L L; Krishna M C; Cook J A; Coleman C N; Biaglow J E; Tuttle S W; Gonzalez F J; Mitchell J B
Protection against SR 4233 (Tirapazamine) aerobic cytotoxicity by the metal chelators desferrioxamine and tiron.
International journal of radiation oncology, biology, physics 1994;30(4):879-85.
1994: DeGraff W; Hahn S M; Mitchell J B; Krishna M C
Free radical modes of cytotoxicity of adriamycin and streptonigrin.
Biochemical pharmacology 1994;48(7):1427-35.
1994: Sullivan F J; Herscher L L; Cook J A; Smith J; Steinberg S M; Epstein A H; Oldfield E H; Goffman T E; Kinsella T J; Mitchell J B
National Cancer Institute (phase II) study of high-grade glioma treated with accelerated hyperfractionated radiation and iododeoxyuridine: results in anaplastic astrocytoma.
International journal of radiation oncology, biology, physics 1994;30(3):583-90.
1994: Liebmann J; DeLuca A M; Coffin D; Keefer L K; Venzon D; Wink D A; Mitchell J B
In vivo radiation protection by nitric oxide modulation.
Cancer research 1994;54(13):3365-8.
1994: Liebmann J; Cook J A; Teague D; Fisher J; Mitchell J B
Cycloheximide inhibits the cytotoxicity of paclitaxel (Taxol).
Anti-cancer drugs 1994;5(3):287-92.
1994: Liebmann J; Cook J A; Fisher J; Teague D; Mitchell J B
Changes in radiation survival curve parameters in human tumor and rodent cells exposed to paclitaxel (Taxol).
International journal of radiation oncology, biology, physics 1994;29(3):559-64.
1994: Tuttle S W; Hazard L; Koch C J; Mitchell J B; Coleman C N; Biaglow J E
Bioreductive metabolism of SR-4233 (WIN 59075) by whole cell suspensions under aerobic and hypoxic conditions: role of the pentose cycle and implications for the mechanism of cytotoxicity observed in air.
International journal of radiation oncology, biology, physics 1994;29(2):357-62.
1994: Hahn S M; Krishna C M; Samuni A; DeGraff W; Cuscela D O; Johnstone P; Mitchell J B
Potential use of nitroxides in radiation oncology.
Cancer research 1994;54(7 Suppl):2006s-2010s.
1994: Liebmann J; Cook J A; Fisher J; Teague D; Mitchell J B
In vitro studies of Taxol as a radiation sensitizer in human tumor cells.
Journal of the National Cancer Institute 1994;86(6):441-6.
1994: Liebmann J; DeLuca A M; Epstein A; Steinberg S M; Morstyn G; Mitchell J B
Protection from lethal irradiation by the combination of stem cell factor and tempol.
Radiation research 1994;137(3):400-4.
1994: Liebmann J; Bourg J; Krishna C M; Glass J; Cook J A; Mitchell J B
Pharmacokinetic properties of nitroxide-labeled albumin in mice.
Life sciences 1994;54(26):PL503-9.
1994: Liebmann J; Cook J A; Lipschultz C; Teague D; Fisher J; Mitchell J B
The influence of Cremophor EL on the cell cycle effects of paclitaxel (Taxol) in human tumor cell lines.
Cancer chemotherapy and pharmacology 1994;33(4):331-9.
1994: Hahn S M; Krishna C M; Mitchell J B
New directions for free radical cancer research and medical applications.
Advances in experimental medicine and biology 1994;366():241-51.
1993: Mitchell J B; Wink D A; DeGraff W; Gamson J; Keefer L K; Krishna M C
Hypoxic mammalian cell radiosensitization by nitric oxide.
Cancer research 1993;53(24):5845-8.
1993: Liebmann J E; Cook J A; Lipschultz C; Teague D; Fisher J; Mitchell J B
Cytotoxic studies of paclitaxel (Taxol) in human tumour cell lines.
British journal of cancer 1993;68(6):1104-9.
1993: Hahn S M; Liebmann J E; Cook J; Fisher J; Goldspiel B; Venzon D; Mitchell J B; Kaufman D
Taxol in combination with doxorubicin or etoposide. Possible antagonism in vitro.
Cancer 1993;72(9):2705-11.
1993: Liebmann J E; Hahn S M; Cook J A; Lipschultz C; Mitchell J B; Kaufman D C
Glutathione depletion by L-buthionine sulfoximine antagonizes taxol cytotoxicity.
Cancer research 1993;53(9):2066-70.
1993: Pogrebniak H W; Matthews W; Black C; Russo A; Mitchell J B; Smith P; Roth J A; Pass H I
Targetted phototherapy with sensitizer-monoclonal antibody conjugate and light.
Surgical oncology 1993;2(1):31-42.
1992: DeGraff W G; Krishna M C; Kaufman D; Mitchell J B
Nitroxide-mediated protection against X-ray- and neocarzinostatin-induced DNA damage.
Free radical biology & medicine 1992;13(5):479-87.
1992: Hahn S M; Wilson L; Krishna C M; Liebmann J; DeGraff W; Gamson J; Samuni A; Venzon D; Mitchell J B
Identification of nitroxide radioprotectors.
Radiation research 1992;132(1):87-93.
1992: Pogrebniak H W; Merino M J; Hahn S M; Mitchell J B; Pass H I
Spin trap salvage from endotoxemia: the role of cytokine down-regulation.
Surgery 1992;112(2):130-9; discussion 138-9.
1992: Krishna M C; Grahame D A; Samuni A; Mitchell J B; Russo A
Oxoammonium cation intermediate in the nitroxide-catalyzed dismutation of superoxide.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(12):5537-41.
1992: Hahn S M; Tochner Z; Krishna C M; Glass J; Wilson L; Samuni A; Sprague M; Venzon D; Glatstein E; Mitchell J B
Tempol, a stable free radical, is a novel murine radiation protector.
Cancer research 1992;52(7):1750-3.
1992: Krishna C M; Liebmann J E; Kaufman D; DeGraff W; Hahn S M; McMurry T; Mitchell J B; Russo A
The catecholic metal sequestering agent 1,2-dihydroxybenzene-3,5-disulfonate confers protection against oxidative cell damage.
Archives of biochemistry and biophysics 1992;294(1):98-106.
1992: Cook J A; Glass J; Lebovics R; Bobo H; Pass H; DeLaney T F; Oldfield E H; Mitchell J B; Glatstein E; Goffman T E
Measurement of thymidine replacement in patients with high grade gliomas, head and neck tumors, and high grade sarcomas after continuous intravenous infusions of 5-iododeoxyuridine.
Cancer research 1992;52(3):719-25.
1992: Goffman T E; Dachowski L J; Bobo H; Oldfield E H; Steinberg S M; Cook J; Mitchell J B; Katz D; Smith R; Glatstein E
Long-term follow-up on National Cancer Institute Phase I/II study of glioblastoma multiforme treated with iododeoxyuridine and hyperfractionated irradiation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1992;10(2):264-8.
1992: Mitchell J B; Coleman C N
Biochemical modification of therapeutic response.
International journal of radiation oncology, biology, physics 1992;22(3):483-4.
1992: Goffman T; Cuscela D; Glass J; Hahn S; Krishna C M; Lupton G; Mitchell J B
Topical application of nitroxide protects radiation-induced alopecia in guinea pigs.
International journal of radiation oncology, biology, physics 1992;22(4):803-6.
1992: Tuttle S W; Varnes M E; Mitchell J B; Biaglow J E
Sensitivity to chemical oxidants and radiation in CHO cell lines deficient in oxidative pentose cycle activity.
International journal of radiation oncology, biology, physics 1992;22(4):671-5.
1992: Biaglow J E; Mitchell J B; Held K
The importance of peroxide and superoxide in the X-ray response.
International journal of radiation oncology, biology, physics 1992;22(4):665-9.
1992: DeGraff W G; Krishna M C; Russo A; Mitchell J B
Antimutagenicity of a low molecular weight superoxide dismutase mimic against oxidative mutagens.
Environmental and molecular mutagenesis 1992;19(1):21-6.
1991: Krishna M C; DeGraff W; Tamura S; Gonzalez F J; Samuni A; Russo A; Mitchell J B
Mechanisms of hypoxic and aerobic cytotoxicity of mitomycin C in Chinese hamster V79 cells.
Cancer research 1991;51(24):6622-8.
1991: DeLaney T F; Smith P D; Thomas G F; Tochner Z A; Sindelar W F; Pass H I; Harrington F S; Bonner R F; Mitchell J B
A light-diffusing device for intraoperative photodynamic therapy in the peritoneal or pleural cavity.
Journal of clinical laser medicine & surgery 1991;9(5):361-6.
1991: Mitchell J B; Glatstein E
Radiation oncology: past achievements and ongoing controversies.
Cancer research 1991;51(18 Suppl):5065s-5073s.
1991: Cook J A; Pass H I; Iype S N; Friedman N; DeGraff W; Russo A; Mitchell J B
Cellular glutathione and thiol measurements from surgically resected human lung tumor and normal lung tissue.
Cancer research 1991;51(16):4287-94.
1991: Mitchell J B; DeGraff W; Kaufman D; Krishna M C; Samuni A; Finkelstein E; Ahn M S; Hahn S M; Gamson J; Russo A
Inhibition of oxygen-dependent radiation-induced damage by the nitroxide superoxide dismutase mimic, tempol.
Archives of biochemistry and biophysics 1991;289(1):62-70.
1991: Hahn S M; Krishna C M; Samuni A; Mitchell J B; Russo A
Mn(III)-desferrioxamine superoxide dismutase-mimic: alternative modes of action.
Archives of biochemistry and biophysics 1991;288(1):215-9.
1991: Bernstein E F; Glass J M; DeGraff W G; Schlegel R; Black C; Fisher J M; Cook S N; Glatstein E; Russo A; Mitchell J B
In vitro photodynamic treatment of normal and human papilloma virus-transfected keratinocytes with photofrin II and red light.
Archives of dermatology 1991;127(5):683-7.
1991: Samuni A; Winkelsberg D; Pinson A; Hahn S M; Mitchell J B; Russo A
Nitroxide stable radicals protect beating cardiomyocytes against oxidative damage.
The Journal of clinical investigation 1991;87(5):1526-30.
1991: Cook J A; Iype S N; Mitchell J B
Differential specificity of monochlorobimane for isozymes of human and rodent glutathione S-transferases.
Cancer research 1991;51(6):1606-12.
1991: Samuni A; Godinger D; Aronovitch J; Russo A; Mitchell J B
Nitroxides block DNA scission and protect cells from oxidative damage.
Biochemistry 1991;30(2):555-61.
1991: Tochner Z; Mitchell J B; Hoekstra H J; Smith P; DeLuca A M; Barnes M; Harrington F; Manyak M; Russo D; Russo A
Photodynamic therapy of the canine peritoneum: normal tissue response to intraperitoneal and intravenous photofrin followed by 630 nm light.
Lasers in surgery and medicine 1991;11(2):158-64.
1991: Samuni A; Mitchell J B; DeGraff W; Krishna C M; Samuni U; Russo A
Nitroxide SOD-mimics: modes of action.
Free radical research communications 1991;12-13 Pt 1():187-94.
1990: Goffman T E; Raubitschek A; Mitchell J B; Glatstein E
The emerging biology of modern radiation oncology.
Cancer research 1990;50(24):7735-44.
1990: Bernstein E F; Thomas G F; Smith P D; Mitchell J B; Glatstein E; Kantor G R; Spielvogel R L; Maiese S C; Russo A
Response of black and white guinea pig skin to photodynamic treatment using 514-nm light and dihematoporphyrin ether.
Archives of dermatology 1990;126(10):1303-7.
1990: Perry R R; Matthews W; Mitchell J B; Russo A; Evans S; Pass H I
Sensitivity of different human lung cancer histologies to photodynamic therapy.
Cancer research 1990;50(14):4272-6.
1990: Mitchell J B; Samuni A; Krishna M C; DeGraff W G; Ahn M S; Samuni U; Russo A
Biologically active metal-independent superoxide dismutase mimics.
Biochemistry 1990;29(11):2802-7.
1990: DeGraff W G; Russo A; Friedman N; Mitchell J B
Misonidazole hypoxic cytotoxicity and chemosensitization in two cell lines with different intracellular glutathione levels.
European journal of cancer (Oxford, England : 1990) 1990;26(1):17-20.
1990: Tochner Z; Barnes M; Mitchell J B; Orr K; Glatstein E; Russo A
Protection by indomethacin against acute radiation esophagitis.
Digestion 1990;47(2):81-7.
1990: Samuni A; Min A; Krishna C M; Mitchell J B; Russo A
SOD-like activity of 5-membered ring nitroxide spin labels.
Advances in experimental medicine and biology 1990;264():85-92.
1990: Samuni A; Krishna C M; Mitchell J B; Collins C R; Russo A
Superoxide reaction with nitroxides.
Free radical research communications 1990;9(3-6):241-9.
1989: Mitchell J B; Russo A; Cook J A; Straus K L; Glatstein E
Radiobiology and clinical application of halogenated pyrimidine radiosensitizers.
International journal of radiation biology 1989;56(5):827-36.
1989: Alegria A E; Samuni A; Mitchell J B; Riesz P; Russo A
Free radicals induced by adriamycin-sensitive and adriamycin-resistant cells: a spin-trapping study.
Biochemistry 1989;28(21):8653-8.
1989: Cook J A; Pass H I; Russo A; Iype S; Mitchell J B
Use of monochlorobimane for glutathione measurements in hamster and human tumor cell lines.
International journal of radiation oncology, biology, physics 1989;16(5):1321-4.
1989: Cook J A; Mitchell J B
Viability measurements in mammalian cell systems.
Analytical biochemistry 1989;179(1):1-7.
1989: Mitchell J B; Cook J A; DeGraff W; Glatstein E; Russo A
Glutathione modulation in cancer treatment: will it work?
International journal of radiation oncology, biology, physics 1989;16(5):1289-95.
1989: Phillips T L; Mitchell J B; DeGraff W G; Russo A; Albright N; Rajpal R
Modification of SR 2508 sensitization in hypoxic V79 cells by manipulation of glutathione levels.
International journal of radiation oncology, biology, physics 1989;16(5):1335-9.
1989: DeGraff W G; Russo A; Gamson J; Mitchell J B
Evaluation of nitroimidazole hypoxic cell radiosensitizers in a human tumor cell line high in intracellular glutathione.
International journal of radiation oncology, biology, physics 1989;16(4):1021-4.
1989: Matthews W; Cook J; Mitchell J B; Perry R R; Evans S; Pass H I
In vitro photodynamic therapy of human lung cancer: investigation of dose-rate effects.
Cancer research 1989;49(7):1718-21.
1989: Atcher R W; Russo A; DeGraff W G; Moore M; Grdina D J; Mitchell J B
Halogenated pyrimidines as radiosensitizers for high-LET radiation.
Radiation research 1989;117(2):351-5.
1988: Kondo T; Gamson J; Mitchell J B; Riesz P
Free radical formation and cell lysis induced by ultrasound in the presence of different rare gases.
International journal of radiation biology 1988;54(6):955-62.
1988: Mitchell J B
Potential applicability of nonclonogenic measurements to clinical oncology.
Radiation research 1988;114(3):401-14.
1988: Kurtzman S H; Russo A; Mitchell J B; DeGraff W; Sindelar W F; Brechbiel M W; Gansow O A; Friedman A M; Hines J J; Gamson J
212Bismuth linked to an antipancreatic carcinoma antibody: model for alpha-particle-emitter radioimmunotherapy.
Journal of the National Cancer Institute 1988;80(6):449-52.
1988: Mitchell J B; Gamson J; Russo A; Friedman N; DeGraff W; Carmichael J; Glatstein E
Chinese hamster pleiotropic multidrug-resistant cells are not radioresistant.
NCI monographs : a publication of the National Cancer Institute 1988;(6):187-91.
1987: Mitchell J B; Russo A
The role of glutathione in radiation and drug induced cytotoxicity.
The British journal of cancer. Supplement 1987;8():96-104.
1986: Russo A; Carmichael J; Friedman N; DeGraff W; Tochner Z; Glatstein E; Mitchell J B
The roles of intracellular glutathione in antineoplastic chemotherapy.
International journal of radiation oncology, biology, physics 1986;12(8):1347-54.
1986: Carmichael J; Friedman N; Tochner Z; Adams D J; Wolf C R; Mitchell J B; Russo A
Inhibition of the protective effect of cyclophosphamide by pre-treatment with buthionine sulfoximine.
International journal of radiation oncology, biology, physics 1986;12(7):1191-3.
1986: Russo A; Tochner Z; Phillips T; Carmichael J; DeGraff W; Friedman N; Fisher J; Mitchell J B
In vivo modulation of glutathione by buthionine sulfoximine: effect on marrow response to melphalan.
International journal of radiation oncology, biology, physics 1986;12(7):1187-9.
1986: Tochner Z; Mitchell J B; Smith P; Harrington F; Glatstein E; Russo D; Russo A
Photodynamic therapy of ascites tumours within the peritoneal cavity.
British journal of cancer 1986;53(6):733-6.
1986: Russo A; DeGraff W; Friedman N; Mitchell J B
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Cancer research 1986;46(6):2845-8.
1985: Russo A; Mitchell J B; DeGraff W; Friedman N; Gamson J
Depletion of cellular glutathione by exogenous spermine in V79 cells: implications for spermine-induced hyperthermic sensitization.
Cancer research 1985;45(10):4910-4.
1985: Russo A; Mitchell J B; Finkelstein E; DeGraff W G; Spiro I J; Gamson J
The effects of cellular glutathione elevation on the oxygen enhancement ratio.
Radiation research 1985;103(2):232-9.
1985: Tochner Z; Mitchell J B; Harrington F S; Smith P; Russo D T; Russo A
Treatment of murine intraperitoneal ovarian ascitic tumor with hematoporphyrin derivative and laser light.
Cancer research 1985;45(7):2983-7.

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