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Timothy Mitchison

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Co-Publications
Name
11
Perlman, Zachary
11
Salmon, Edward
9
Field, Christine
8
Charras, Guillaume
8
Groen, Aaron
8
Straight, Aaron
8
Walczak, Claire
7
Kapoor, Tarun
7
Desai, Arshad
6
Hyman, Anthony
6
Kueh, Hao Yuan
6
Coughlin, Margaret
6
Welch, Matt
5
Yarrow, Justin
5
Brieher, William

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Publications

TOP 3
Huang Hsiao-Chun; Shi Jue; Orth James D; Mitchison Timothy J
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
Dumont Sophie; Mitchison Timothy J
Force and length in the mitotic spindle.
Charras Guillaume T; Mitchison Timothy J; Mahadevan L
Animal cell hydraulics.

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All Publications

2009: Huang Hsiao-Chun; Shi Jue; Orth James D; Mitchison Timothy J
Evidence that mitotic exit is a better cancer therapeutic target than spindle assembly.
Cancer cell 2009;16(4):347-58.
2009: Dumont Sophie; Mitchison Timothy J
Force and length in the mitotic spindle.
Current biology : CB 2009;19(17):R749-61.
2009: Charras Guillaume T; Mitchison Timothy J; Mahadevan L
Animal cell hydraulics.
Journal of cell science 2009;122(Pt 18):3233-41.
2009: Kueh Hao Yuan; Mitchison Timothy J
Structural plasticity in actin and tubulin polymer dynamics.
Science (New York, N.Y.) 2009;325(5943):960-3.
2009: Maresca Thomas J; Groen Aaron C; Gatlin Jesse C; Ohi Ryoma; Mitchison Timothy J; Salmon Edward D
Spindle assembly in the absence of a RanGTP gradient requires localized CPC activity.
Current biology : CB 2009;19(14):1210-5.
2009: Dumont Sophie; Mitchison Timothy J
Compression regulates mitotic spindle length by a mechanochemical switch at the poles.
Current biology : CB 2009;19(13):1086-95.
2009: Needleman Daniel J; Xu Yangqing; Mitchison Timothy J
Pin-hole array correlation imaging: highly parallel fluorescence correlation spectroscopy.
Biophysical journal 2009;96(12):5050-9.
2009: Niethammer Philipp; Grabher Clemens; Look A Thomas; Mitchison Timothy J
A tissue-scale gradient of hydrogen peroxide mediates rapid wound detection in zebrafish.
Nature 2009;459(7249):996-9.
2009: Groen Aaron C; Maresca Thomas J; Gatlin Jesse C; Salmon Edward D; Mitchison Timothy J
Functional overlap of microtubule assembly factors in chromatin-promoted spindle assembly.
Molecular biology of the cell 2009;20(11):2766-73.
2009: Wühr Martin; Mitchison Timothy J; Field Christine M
Size and speed go hand in hand in cytokinesis.
Cell 2009;137(5):798-800.
2009: Wühr Martin; Dumont Sophie; Groen Aaron C; Needleman Daniel J; Mitchison Timothy J
How does a millimeter-sized cell find its center?
Cell cycle (Georgetown, Tex.) 2009;8(8):1115-21.
2009: Gatlin Jesse C; Matov Alexandre; Groen Aaron C; Needleman Daniel J; Maresca Thomas J; Danuser Gaudenz; Mitchison Timothy J; Salmon E D
Spindle fusion requires dynein-mediated sliding of oppositely oriented microtubules.
Current biology : CB 2009;19(4):287-96.
2009: Tsui Melody; Xie Tiao; Orth James D; Carpenter Anne E; Rudnicki Stewart; Kim Suejong; Shamu Caroline E; Mitchison Timothy J
An intermittent live cell imaging screen for siRNA enhancers and suppressors of a kinesin-5 inhibitor.
PloS one 2009;4(10):e7339.
2008: Orth James D; Tang Yangzhong; Shi Jade; Loy Clement T; Amendt Christiane; Wilm Claudia; Zenke Frank T; Mitchison Timothy J
Quantitative live imaging of cancer and normal cells treated with Kinesin-5 inhibitors indicates significant differences in phenotypic responses and cell fate.
Molecular cancer therapeutics 2008;7(11):3480-9.
2008: Wühr Martin; Mitchison Timothy J; Field Christine M
Mitosis: new roles for myosin-X and actin at the spindle.
Current biology : CB 2008;18(19):R912-4.
2008: Kueh Hao Yuan; Brieher William M; Mitchison Timothy J
Dynamic stabilization of actin filaments.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16531-6.
2008: Wühr Martin; Chen Yao; Dumont Sophie; Groen Aaron C; Needleman Daniel J; Salic Adrian; Mitchison Timothy J
Evidence for an upper limit to mitotic spindle length.
Current biology : CB 2008;18(16):1256-61.
2008: Kueh Hao Yuan; Charras Guillaume T; Mitchison Timothy J; Brieher William M
Actin disassembly by cofilin, coronin, and Aip1 occurs in bursts and is inhibited by barbed-end cappers.
The Journal of cell biology 2008;182(2):341-53.
2008: Groen Aaron C; Needleman Daniel; Brangwynne Clifford; Gradinaru Christain; Fowler Brandon; Mazitschek Ralph; Mitchison Timothy J
A novel small-molecule inhibitor reveals a possible role of kinesin-5 in anastral spindle-pole assembly.
Journal of cell science 2008;121(Pt 14):2293-300.
2008: Mitchison T J; Charras G T; Mahadevan L
Implications of a poroelastic cytoplasm for the dynamics of animal cell shape.
Seminars in cell & developmental biology 2008;19(3):215-23.
2008: Hu Chi-Kuo; Coughlin Margaret; Field Christine M; Mitchison Timothy J
Cell polarization during monopolar cytokinesis.
The Journal of cell biology 2008;181(2):195-202.
2008: Niethammer Philipp; Kueh Hao Yuan; Mitchison Timothy J
Spatial patterning of metabolism by mitochondria, oxygen, and energy sinks in a model cytoplasm.
Current biology : CB 2008;18(8):586-91.
2008: Charras Guillaume T; Coughlin Margaret; Mitchison Timothy J; Mahadevan L
Life and times of a cellular bleb.
Biophysical journal 2008;94(5):1836-53.
2008: Salic Adrian; Mitchison Timothy J
A chemical method for fast and sensitive detection of DNA synthesis in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(7):2415-20.
2008: Galkin Vitold E; Orlova Albina; Brieher William; Kueh Hao Yuan; Mitchison Timothy J; Egelman Edward H
Coronin-1A stabilizes F-actin by bridging adjacent actin protomers and stapling opposite strands of the actin filament.
Journal of molecular biology 2008;376(3):607-13.
2007: Irimia Daniel; Charras Guillaume; Agrawal Nitin; Mitchison Timothy; Toner Mehmet
Polar stimulation and constrained cell migration in microfluidic channels.
Lab on a chip 2007;7(12):1783-90.
2007: Vrabioiu Alina M; Mitchison Timothy J
Symmetry of septin hourglass and ring structures.
Journal of molecular biology 2007;372(1):37-49.
2007: Burbank Kendra S; Mitchison Timothy J; Fisher Daniel S
Slide-and-cluster models for spindle assembly.
Current biology : CB 2007;17(16):1373-83.
2007: Ohi Ryoma; Burbank Kendra; Liu Qing; Mitchison Timothy J
Nonredundant functions of Kinesin-13s during meiotic spindle assembly.
Current biology : CB 2007;17(11):953-9.
2007: Li Juying; Brieher William M; Scimone M Lucila; Kang Shin Jung; Zhu Hong; Yin Helen; von Andrian Ulrich H; Mitchison Timothy; Yuan Junying
Caspase-11 regulates cell migration by promoting Aip1-Cofilin-mediated actin depolymerization.
Nature cell biology 2007;9(3):276-86.
2006: Charras Guillaume T; Hu Chi-Kuo; Coughlin Margaret; Mitchison Timothy J
Reassembly of contractile actin cortex in cell blebs.
The Journal of cell biology 2006;175(3):477-90.
2006: Burbank Kendra S; Groen Aaron C; Perlman Zachary E; Fisher Daniel S; Mitchison Timothy J
A new method reveals microtubule minus ends throughout the meiotic spindle.
The Journal of cell biology 2006;175(3):369-75.
2006: Ribbeck Katharina; Mitchison Timothy J
Meiotic spindle: sculpted by severing.
Current biology : CB 2006;16(21):R923-5.
2006: Brieher William M; Kueh Hao Yuan; Ballif Bryan A; Mitchison Timothy J
Rapid actin monomer-insensitive depolymerization of Listeria actin comet tails by cofilin, coronin, and Aip1.
The Journal of cell biology 2006;175(2):315-24.
2006: Vrabioiu Alina M; Mitchison Timothy J
Structural insights into yeast septin organization from polarized fluorescence microscopy.
Nature 2006;443(7110):466-9.
2006: Burbank Kendra S; Mitchison Timothy J
Microtubule dynamic instability.
Current biology : CB 2006;16(14):R516-7.
2006: Eggert Ulrike S; Mitchison Timothy J
Small molecule screening by imaging.
Current opinion in chemical biology 2006;10(3):232-7.
2006: Ribbeck Katharina; Groen Aaron C; Santarella Rachel; Bohnsack Markus T; Raemaekers Tim; Köcher Thomas; Gentzel Marc; Görlich Dirk; Wilm Matthias; Carmeliet Geert; Mitchison Timothy J; Ellenberg Jan; Hoenger Andreas; Mattaj Iain W
NuSAP, a mitotic RanGTP target that stabilizes and cross-links microtubules.
Molecular biology of the cell 2006;17(6):2646-60.
2006: De Wall Stephen L; Painter Corrie; Stone Jennifer D; Bandaranayake Rajintha; Wiley Don C; Mitchison Timothy J; Stern Lawrence J; DeDecker Brian S
Noble metals strip peptides from class II MHC proteins.
Nature chemical biology 2006;2(4):197-201.
2006: Eggert Ulrike S; Field Christine M; Mitchison Timothy J
Small molecules in an RNAi world.
Molecular bioSystems 2006;2(2):93-6.
2006: Eggert Ulrike S; Mitchison Timothy J; Field Christine M
Animal cytokinesis: from parts list to mechanisms.
Annual review of biochemistry 2006;75():543-66.
2006: Maliga Zoltan; Mitchison Timothy J
Small-molecule and mutational analysis of allosteric Eg5 inhibition by monastrol.
BMC chemical biology 2006;6():2.
2005: Chang Paul; Coughlin Margaret; Mitchison Timothy J
Tankyrase-1 polymerization of poly(ADP-ribose) is required for spindle structure and function.
Nature cell biology 2005;7(11):1133-9.
2005: Degterev Alexei; Huang Zhihong; Boyce Michael; Li Yaqiao; Jagtap Prakash; Mizushima Noboru; Cuny Gregory D; Mitchison Timothy J; Moskowitz Michael A; Yuan Junying
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
Nature chemical biology 2005;1(2):112-9.
2005: Mitchison T J; Maddox P; Gaetz J; Groen A; Shirasu M; Desai A; Salmon E D; Kapoor T M
Roles of polymerization dynamics, opposed motors, and a tensile element in governing the length of Xenopus extract meiotic spindles.
Molecular biology of the cell 2005;16(6):3064-76.
2005: Charras Guillaume T; Yarrow Justin C; Horton Mike A; Mahadevan L; Mitchison T J
Non-equilibration of hydrostatic pressure in blebbing cells.
Nature 2005;435(7040):365-9.
2005: Mitchison T J
Mechanism and function of poleward flux in Xenopus extract meiotic spindles.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2005;360(1455):623-9.
2005: Yarrow Justin C; Totsukawa Go; Charras Guillaume T; Mitchison Timothy J
Screening for cell migration inhibitors via automated microscopy reveals a Rho-kinase inhibitor.
Chemistry & biology 2005;12(3):385-95.
2005: Perlman Zachary E; Mitchison Timothy J; Mayer Thomas U
High-content screening and profiling of drug activity in an automated centrosome-duplication assay.
Chembiochem : a European journal of chemical biology 2005;6(1):145-51.
2005: Mitchison Timothy J
Small-molecule screening and profiling by using automated microscopy.
Chembiochem : a European journal of chemical biology 2005;6(1):33-9.
2005: Valentine M T; Perlman Z E; Mitchison T J; Weitz D A
Mechanical properties of Xenopus egg cytoplasmic extracts.
Biophysical journal 2005;88(1):680-9.
2005: Straight Aaron F; Field Christine M; Mitchison Timothy J
Anillin binds nonmuscle myosin II and regulates the contractile ring.
Molecular biology of the cell 2005;16(1):193-201.
2004: Miyamoto David T; Perlman Zachary E; Burbank Kendra S; Groen Aaron C; Mitchison Timothy J
The kinesin Eg5 drives poleward microtubule flux in Xenopus laevis egg extract spindles.
The Journal of cell biology 2004;167(5):813-8.
2004: Chang Paul; Jacobson Myron K; Mitchison Timothy J
Poly(ADP-ribose) is required for spindle assembly and structure.
Nature 2004;432(7017):645-9.
2004: Eggert Ulrike S; Kiger Amy A; Richter Constance; Perlman Zachary E; Perrimon Norbert; Mitchison Timothy J; Field Christine M
Parallel chemical genetic and genome-wide RNAi screens identify cytokinesis inhibitors and targets.
PLoS biology 2004;2(12):e379.
2004: Mitchison T J; Maddox P; Groen A; Cameron L; Perlman Z; Ohi R; Desai A; Salmon E D; Kapoor T M
Bipolarization and poleward flux correlate during Xenopus extract spindle assembly.
Molecular biology of the cell 2004;15(12):5603-15.
2004: Ramamurthy Bhagavathi; Yengo Christopher M; Straight Aaron F; Mitchison Timothy J; Sweeney H Lee
Kinetic mechanism of blebbistatin inhibition of nonmuscle myosin IIb.
Biochemistry 2004;43(46):14832-9.
2004: Perlman Zachary E; Slack Michael D; Feng Yan; Mitchison Timothy J; Wu Lani F; Altschuler Steven J
Multidimensional drug profiling by automated microscopy.
Science (New York, N.Y.) 2004;306(5699):1194-8.
2004: Shirasu-Hiza Mimi; Perlman Zachary E; Wittmann Torsten; Karsenti Eric; Mitchison Timothy J
Eg5 causes elongation of meiotic spindles when flux-associated microtubule depolymerization is blocked.
Current biology : CB 2004;14(21):1941-5.
2004: Groen Aaron C; Cameron Lisa A; Coughlin Margaret; Miyamoto David T; Mitchison Timothy J; Ohi Ryoma
XRHAMM functions in ran-dependent microtubule nucleation and pole formation during anastral spindle assembly.
Current biology : CB 2004;14(20):1801-11.
2004: Yarrow Justin C; Perlman Zachary E; Westwood Nicholas J; Mitchison Timothy J
A high-throughput cell migration assay using scratch wound healing, a comparison of image-based readout methods.
BMC biotechnology 2004;4():21.
2004: Margalit Danielle N; Romberg Laura; Mets Rebecca B; Hebert Alan M; Mitchison Timothy J; Kirschner Marc W; RayChaudhuri Debabrata
Targeting cell division: small-molecule inhibitors of FtsZ GTPase perturb cytokinetic ring assembly and induce bacterial lethality.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(32):11821-6.
2004: Miller Stephen C; Mitchison Timothy J
Synthesis and phenotypic screening of a Guanine-mimetic library.
Chembiochem : a European journal of chemical biology 2004;5(7):1010-2.
2004: Valentine M T; Perlman Z E; Gardel M L; Shin J H; Matsudaira P; Mitchison T J; Weitz D A
Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials.
Biophysical journal 2004;86(6):4004-14.
2004: Venkatesh Natarajan; Feng Yan; DeDecker Brian; Yacono Patrick; Golan David; Mitchison Timothy; McKeon Frank
Chemical genetics to identify NFAT inhibitors: potential of targeting calcium mobilization in immunosuppression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(24):8969-74.
2004: Ohi Ryoma; Sapra Tanuj; Howard Jonathan; Mitchison Timothy J
Differentiation of cytoplasmic and meiotic spindle assembly MCAK functions by Aurora B-dependent phosphorylation.
Molecular biology of the cell 2004;15(6):2895-906.
2004: Brieher William M; Coughlin Margaret; Mitchison Timothy J
Fascin-mediated propulsion of Listeria monocytogenes independent of frequent nucleation by the Arp2/3 complex.
The Journal of cell biology 2004;165(2):233-42.
2004: Tirnauer Jennifer S; Salmon E D; Mitchison Timothy J
Microtubule plus-end dynamics in Xenopus egg extract spindles.
Molecular biology of the cell 2004;15(4):1776-84.
2004: Corcoran Lisa J; Mitchison Timothy J; Liu Qing
A novel action of histone deacetylase inhibitors in a protein aggresome disease model.
Current biology : CB 2004;14(6):488-92.
2004: Romberg Laura; Mitchison Timothy J
Rate-limiting guanosine 5'-triphosphate hydrolysis during nucleotide turnover by FtsZ, a prokaryotic tubulin homologue involved in bacterial cell division.
Biochemistry 2004;43(1):282-8.
2004: Vrabioiu Alina M; Gerber Scott A; Gygi Steven P; Field Christine M; Mitchison Timothy J
The majority of the Saccharomyces cerevisiae septin complexes do not exchange guanine nucleotides.
The Journal of biological chemistry 2004;279(4):3111-8.
2004: Limouze John; Straight Aaron F; Mitchison Timothy; Sellers James R
Specificity of blebbistatin, an inhibitor of myosin II.
Journal of muscle research and cell motility 2004;25(4-5):337-41.
2003: Ohi Ryoma; Coughlin Margaret L; Lane William S; Mitchison Timothy J
An inner centromere protein that stimulates the microtubule depolymerizing activity of a KinI kinesin.
Developmental cell 2003;5(2):309-21.
2003: Canman Julie C; Cameron Lisa A; Maddox Paul S; Straight Aaron; Tirnauer Jennifer S; Mitchison Timothy J; Fang Guowei; Kapoor Tarun M; Salmon E D
Determining the position of the cell division plane.
Nature 2003;424(6952):1074-8.
2003: Maddox Paul; Straight Aaron; Coughlin Peg; Mitchison Timothy J; Salmon Edward D
Direct observation of microtubule dynamics at kinetochores in Xenopus extract spindles: implications for spindle mechanics.
The Journal of cell biology 2003;162(3):377-82.
2003: Xu Jingsong; Wang Fei; Van Keymeulen Alexandra; Herzmark Paul; Straight Aaron; Kelly Kathleen; Takuwa Yoh; Sugimoto Naotoshi; Mitchison Timothy; Bourne Henry R
Divergent signals and cytoskeletal assemblies regulate self-organizing polarity in neutrophils.
Cell 2003;114(2):201-14.
2003: Yarrow Justin C; Lechler Terry; Li Rong; Mitchison Timothy J
Rapid de-localization of actin leading edge components with BDM treatment.
BMC cell biology 2003;4():5.
2003: Yarrow J C; Feng Y; Perlman Z E; Kirchhausen T; Mitchison T J
Phenotypic screening of small molecule libraries by high throughput cell imaging.
Combinatorial chemistry & high throughput screening 2003;6(4):279-86.
2003: Feng Yan; Yu Sidney; Lasell Troy K R; Jadhav Ashutosh P; Macia Eric; Chardin Pierre; Melancon Paul; Roth Michael; Mitchison Timothy; Kirchhausen Tomas
Exo1: a new chemical inhibitor of the exocytic pathway.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6469-74.
2003: Shirasu-Hiza Mimi; Coughlin Peg; Mitchison Tim
Identification of XMAP215 as a microtubule-destabilizing factor in Xenopus egg extract by biochemical purification.
The Journal of cell biology 2003;161(2):349-58.
2003: Straight Aaron F; Cheung Amy; Limouze John; Chen Irene; Westwood Nick J; Sellers James R; Mitchison Timothy J
Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.
Science (New York, N.Y.) 2003;299(5613):1743-7.
2003: Miyamoto David T; Perlman Zachary E; Mitchison Timothy J; Shirasu-Hiza Mimi
Dynamics of the mitotic spindle--potential therapeutic targets.
Progress in cell cycle research 2003;5():349-60.
2002: Peterson Jeffrey R; Mitchison Timothy J
Small molecules, big impact: a history of chemical inhibitors and the cytoskeleton.
Chemistry & biology 2002;9(12):1275-85.
2002: Kinoshita Makoto; Field Christine M; Coughlin Margaret L; Straight Aaron F; Mitchison Timothy J
Self- and actin-templated assembly of Mammalian septins.
Developmental cell 2002;3(6):791-802.
2002: Tirnauer Jennifer S; Canman Julie C; Salmon E D; Mitchison Timothy J
EB1 targets to kinetochores with attached, polymerizing microtubules.
Molecular biology of the cell 2002;13(12):4308-16.
2002: Macara Ian G; Baldarelli Richard; Field Christine M; Glotzer Michael; Hayashi Yasuhide; Hsu Shu-Chan; Kennedy Mary B; Kinoshita Makoto; Longtine Mark; Low Claudia; Maltais Lois J; McKenzie Louise; Mitchison Timothy J; Nishikawa Toru; Noda Makoto; Petty Elizabeth M; Peifer Mark; Pringle John R; Robinson Phillip J; Roth Dagmar; Russell S E Hilary; Stuhlmann Heidi; Tanaka Manami; Tanaka Tomoo; Trimble William S; Ware Jerry; Zeleznik-Le Nancy J; Zieger Barbara
Mammalian septins nomenclature.
Molecular biology of the cell 2002;13(12):4111-3.
2002: Mitchison Timothy J; Field Christine M
Cytoskeleton: what does GTP do for septins?
Current biology : CB 2002;12(22):R788-90.
2002: Tirnauer Jennifer S; Grego Sonia; Salmon E D; Mitchison Timothy J
EB1-microtubule interactions in Xenopus egg extracts: role of EB1 in microtubule stabilization and mechanisms of targeting to microtubules.
Molecular biology of the cell 2002;13(10):3614-26.
2002: Maliga Zoltan; Kapoor Tarun M; Mitchison Timothy J
Evidence that monastrol is an allosteric inhibitor of the mitotic kinesin Eg5.
Chemistry & biology 2002;9(9):989-96.
2002: Watanabe Naoki; Mitchison Timothy J
Single-molecule speckle analysis of actin filament turnover in lamellipodia.
Science (New York, N.Y.) 2002;295(5557):1083-6.
2002: Cheung A; Dantzig J A; Hollingworth S; Baylor S M; Goldman Y E; Mitchison T J; Straight A F
A small-molecule inhibitor of skeletal muscle myosin II.
Nature cell biology 2002;4(1):83-8.
2002: Mitchison T J
Probing cell division with "chemical genetics".
Harvey lectures 2002;98():19-40.
2001: Peterson J R; Lokey R S; Mitchison T J; Kirschner M W
A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(19):10624-9.
2001: Mitchison T J
Psychosine, cytokinesis, and orphan receptors. Unexpected connections.
The Journal of cell biology 2001;153(2):F1-3.
2001: Degterev A; Lugovskoy A; Cardone M; Mulley B; Wagner G; Mitchison T; Yuan J
Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL.
Nature cell biology 2001;3(2):173-82.
2001: Mitchison T J; Salmon E D
Mitosis: a history of division.
Nature cell biology 2001;3(1):E17-21.
2000: Kapoor T M; Mayer T U; Coughlin M L; Mitchison T J
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5.
The Journal of cell biology 2000;150(5):975-88.
2000: Oegema K; Savoian M S; Mitchison T J; Field C M
Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis.
The Journal of cell biology 2000;150(3):539-52.
2000: Haggarty S J; Mayer T U; Miyamoto D T; Fathi R; King R W; Mitchison T J; Schreiber S L
Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis.
Chemistry & biology 2000;7(4):275-86.
2000: Taunton J; Rowning B A; Coughlin M L; Wu M; Moon R T; Mitchison T J; Larabell C A
Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP.
The Journal of cell biology 2000;148(3):519-30.
2000: Kirschner M; Gerhart J; Mitchison T
Molecular "vitalism".
Cell 2000;100(1):79-88.
1999: Mallavarapu A; Sawin K; Mitchison T
A switch in microtubule dynamics at the onset of anaphase B in the mitotic spindle of Schizosaccharomyces pombe.
Current biology : CB 1999;9(23):1423-6.
1999: Mayer T U; Kapoor T M; Haggarty S J; King R W; Schreiber S L; Mitchison T J
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen.
Science (New York, N.Y.) 1999;286(5441):971-4.
1999: Mallavarapu A; Mitchison T
Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction.
The Journal of cell biology 1999;146(5):1097-106.
1999: Kapoor T M; Mitchison T J
Allele-specific activators and inhibitors for kinesin.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(16):9106-11.
1999: Weiner O D; Servant G; Welch M D; Mitchison T J; Sedat J W; Bourne H R
Spatial control of actin polymerization during neutrophil chemotaxis.
Nature cell biology 1999;1(2):75-81.
1999: Oegema K; Wiese C; Martin O C; Milligan R A; Iwamatsu A; Mitchison T J; Zheng Y
Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules.
The Journal of cell biology 1999;144(4):721-33.
1999: Desai A; Verma S; Mitchison T J; Walczak C E
Kin I kinesins are microtubule-destabilizing enzymes.
Cell 1999;96(1):69-78.
1999: Desai A; Murray A; Mitchison T J; Walczak C E
The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro.
Methods in cell biology 1999;61():385-412.
1998: Frazier J A; Wong M L; Longtine M S; Pringle J R; Mann M; Mitchison T J; Field C
Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function.
The Journal of cell biology 1998;143(3):737-49.
1998: Walczak C E; Vernos I; Mitchison T J; Karsenti E; Heald R
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity.
Current biology : CB 1998;8(16):903-13.
1998: Welch M D; Rosenblatt J; Skoble J; Portnoy D A; Mitchison T J
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation.
Science (New York, N.Y.) 1998;281(5373):105-8.
1998: Field C M; Oegema K; Zheng Y; Mitchison T J; Walczak C E
Purification of cytoskeletal proteins using peptide antibodies.
Methods in enzymology 1998;298():525-41.
1998: Oegema K; Desai A; Wong M L; Mitchison T J; Field C M
Purification and assay of a septin complex from Drosophila embryos.
Methods in enzymology 1998;298():279-95.
1998: Desai A; Mitchison T J
Preparation and characterization of caged fluorescein tubulin.
Methods in enzymology 1998;298():125-32.
1998: Welch M D; Mitchison T J
Purification and assay of the platelet Arp2/3 complex.
Methods in enzymology 1998;298():52-61.
1998: Mitchison T J; Sawin K E; Theriot J A; Gee K; Mallavarapu A
Caged fluorescent probes.
Methods in enzymology 1998;291():63-78.
1997: Desai A; Deacon H W; Walczak C E; Mitchison T J
A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(23):12378-83.
1997: Welch M D; DePace A H; Verma S; Iwamatsu A; Mitchison T J
The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly.
The Journal of cell biology 1997;138(2):375-84.
1997: Oegema K; Mitchison T J
Rappaport rules: cleavage furrow induction in animal cells.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(10):4817-20.
1997: Rosenblatt J; Agnew B J; Abe H; Bamburg J R; Mitchison T J
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails.
The Journal of cell biology 1997;136(6):1323-32.
1997: Walczak C E; Verma S; Mitchison T J
XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts.
The Journal of cell biology 1997;136(4):859-70.
1997: Welch M D; Mallavarapu A; Rosenblatt J; Mitchison T J
Actin dynamics in vivo.
Current opinion in cell biology 1997;9(1):54-61.
1997: Cramer L P; Mitchison T J
Investigation of the mechanism of retraction of the cell margin and rearward flow of nodules during mitotic cell rounding.
Molecular biology of the cell 1997;8(1):109-19.
1997: Welch M D; Iwamatsu A; Mitchison T J
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes.
Nature 1997;385(6613):265-9.
1996: Belmont L; Mitchison T; Deacon H W
Catastrophic revelations about Op18/stathmin.
Trends in biochemical sciences 1996;21(6):197-8.
1996: Walczak C E; Mitchison T J
Kinesin-related proteins at mitotic spindle poles: function and regulation.
Cell 1996;85(7):943-6.
1996: Field C M; al-Awar O; Rosenblatt J; Wong M L; Alberts B; Mitchison T J
A purified Drosophila septin complex forms filaments and exhibits GTPase activity.
The Journal of cell biology 1996;133(3):605-16.
1996: Mitchison T J; Cramer L P
Actin-based cell motility and cell locomotion.
Cell 1996;84(3):371-9.
1996: Belmont L D; Mitchison T J
Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules.
Cell 1996;84(4):623-31.
1996: Walczak C E; Mitchison T J; Desai A
XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly.
Cell 1996;84(1):37-47.
1995: Zheng Y; Wong M L; Alberts B; Mitchison T
Nucleation of microtubule assembly by a gamma-tubulin-containing ring complex.
Nature 1995;378(6557):578-83.
1995: Cramer L P; Mitchison T J
Myosin is involved in postmitotic cell spreading.
The Journal of cell biology 1995;131(1):179-89.
1995: Hirano T; Mitchison T J; Swedlow J R
The SMC family: from chromosome condensation to dosage compensation.
Current opinion in cell biology 1995;7(3):329-36.
1995: Sawin K E; Mitchison T J
Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(10):4289-93.
1995: Rosenblatt J; Peluso P; Mitchison T J
The bulk of unpolymerized actin in Xenopus egg extracts is ATP-bound.
Molecular biology of the cell 1995;6(2):227-36.
1995: Wordeman L; Mitchison T J
Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis.
The Journal of cell biology 1995;128(1-2):95-104.
1995: Desai A; Mitchison T J
A new role for motor proteins as couplers to depolymerizing microtubules.
The Journal of cell biology 1995;128(1-2):1-4.
1994: Hirano T; Mitchison T J
A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro.
Cell 1994;79(3):449-58.
1994: Theriot J A; Rosenblatt J; Portnoy D A; Goldschmidt-Clermont P J; Mitchison T J
Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts.
Cell 1994;76(3):505-17.
1994: Cramer L P; Mitchison T J; Theriot J A
Actin-dependent motile forces and cell motility.
Current opinion in cell biology 1994;6(1):82-6.
1994: Sawin K E; Mitchison T J
Microtubule flux in mitosis is independent of chromosomes, centrosomes, and antiparallel microtubules.
Molecular biology of the cell 1994;5(2):217-26.
1993: Cramer L; Mitchison T J
Moving and stationary actin filaments are involved in spreading of postmitotic PtK2 cells.
The Journal of cell biology 1993;122(4):833-43.
1993: Mitchison T J
Localization of an exchangeable GTP binding site at the plus end of microtubules.
Science (New York, N.Y.) 1993;261(5124):1044-7.
1993: Hirano T; Mitchison T J
Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts.
The Journal of cell biology 1993;120(3):601-12.
1993: Hyman A A; Mitchison T J
An assay for the activity of microtubule-based motors on the kinetochores of isolated Chinese hamster ovary chromosomes.
Methods in cell biology 1993;39():267-76.
1992: Mitchison T J; Salmon E D
Poleward kinetochore fiber movement occurs during both metaphase and anaphase-A in newt lung cell mitosis.
The Journal of cell biology 1992;119(3):569-82.
1992: Hyman A A; Salser S; Drechsel D N; Unwin N; Mitchison T J
Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP.
Molecular biology of the cell 1992;3(10):1155-67.
1992: Sawin K E; LeGuellec K; Philippe M; Mitchison T J
Mitotic spindle organization by a plus-end-directed microtubule motor.
Nature 1992;359(6395):540-3.
1992: Hyman A A; Middleton K; Centola M; Mitchison T J; Carbon J
Microtubule-motor activity of a yeast centromere-binding protein complex.
Nature 1992;359(6395):533-6.
1992: Theriot J A; Mitchison T J
Comparison of actin and cell surface dynamics in motile fibroblasts.
The Journal of cell biology 1992;119(2):367-77.
1992: Symons M H; Mitchison T J
A GTPase controls cell-substrate adhesion in Xenopus XTC fibroblasts.
The Journal of cell biology 1992;118(5):1235-44.
1992: Theriot J A; Mitchison T J; Tilney L G; Portnoy D A
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization.
Nature 1992;357(6375):257-60.
1992: Mitchison T J
Self-organization of polymer-motor systems in the cytoskeleton.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1992;336(1276):99-106.
1992: Sawin K E; Mitchison T J; Wordeman L G
Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies.
Journal of cell science 1992;101 ( Pt 2)():303-13.
1992: Mitchison T J
Actin based motility on retraction fibers in mitotic PtK2 cells.
Cell motility and the cytoskeleton 1992;22(2):135-51.
1991: Hirano T; Mitchison T J
Cell cycle control of higher-order chromatin assembly around naked DNA in vitro.
The Journal of cell biology 1991;115(6):1479-89.
1991: Reinsch S S; Mitchison T J; Kirschner M
Microtubule polymer assembly and transport during axonal elongation.
The Journal of cell biology 1991;115(2):365-79.
1991: Symons M H; Mitchison T J
Control of actin polymerization in live and permeabilized fibroblasts.
The Journal of cell biology 1991;114(3):503-13.
1991: Theriot J A; Mitchison T J
Actin microfilament dynamics in locomoting cells.
Nature 1991;352(6331):126-31.
1991: Wordeman L; Steuer E R; Sheetz M P; Mitchison T
Chemical subdomains within the kinetochore domain of isolated CHO mitotic chromosomes.
The Journal of cell biology 1991;114(2):285-94.
1991: Hyman A A; Mitchison T J
Two different microtubule-based motor activities with opposite polarities in kinetochores.
Nature 1991;351(6323):206-11.
1991: Sawin K E; Mitchison T J
Poleward microtubule flux mitotic spindles assembled in vitro.
The Journal of cell biology 1991;112(5):941-54.
1991: Sawin K E; Mitchison T J
Mitotic spindle assembly by two different pathways in vitro.
The Journal of cell biology 1991;112(5):925-40.
1991: Hyman A; Drechsel D; Kellogg D; Salser S; Sawin K; Steffen P; Wordeman L; Mitchison T
Preparation of modified tubulins.
Methods in enzymology 1991;196():478-85.
1990: Belmont L D; Hyman A A; Sawin K E; Mitchison T J
Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts.
Cell 1990;62(3):579-89.
1990: Hyman A A; Mitchison T J
Modulation of microtubule stability by kinetochores in vitro.
The Journal of cell biology 1990;110(5):1607-16.
1990: Sawin K; Mitchison T
Cell biology. Motoring in the spindle.
Nature 1990;345(6270):22-3.
1990: Mitchison T J; Sawin K E
Tubulin flux in the mitotic spindle: where does it come from, where is it going?
Cell motility and the cytoskeleton 1990;16(2):93-8.
1989: Mitchison T J
Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.
The Journal of cell biology 1989;109(2):637-52.
1989: Mitchison T J
Mitosis: basic concepts.
Current opinion in cell biology 1989;1(1):67-74.
1988: Koshland D E; Mitchison T J; Kirschner M W
Polewards chromosome movement driven by microtubule depolymerization in vitro.
Nature 1988;331(6156):499-504.
1988: Mitchison T J
Microtubule dynamics and kinetochore function in mitosis.
Annual review of cell biology 1988;4():527-49.
1985: Vale R D; Schnapp B J; Mitchison T; Steuer E; Reese T S; Sheetz M P
Different axoplasmic proteins generate movement in opposite directions along microtubules in vitro.
Cell 1985;43(3 Pt 2):623-32.

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