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Raj Mitra

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Anatomy

Chemicals & Drugs

Physiology

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Immunohistochemistry

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Mitsuo Goto; Raj S Mitra; Min Liu; Julia Lee; Bradley S Henson; Thomas Carey; Carol R Bradford; Mark E Prince; Cun-Yu Wang; Eric R Fearon; Nisha J D'Silva
Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck.
Raj S Mitra; Mitsuo Goto; Julia S Lee; Diana Maldonado; Jeremy Taylor; Quintin Pan; Thomas Carey; Carol R Bradford; Mark E Prince; Kitrina G Cordell; Keith Lough Kirkwood; Nisha J D'Silva
Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.
Bradley S Henson; Fei Li; Derek D Coatney; Thomas Carey; Raj S Mitra; Keith Lough Kirkwood; Nisha J D'Silva
An orthotopic floor-of-mouth model for locoregional growth and spread of human squamous cell carcinoma.

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2010: Mitsuo Goto; Raj S Mitra; Min Liu; Julia Lee; Bradley S Henson; Thomas Carey; Carol R Bradford; Mark E Prince; Cun-Yu Wang; Eric R Fearon; Nisha J D'Silva
Rap1 stabilizes beta-catenin and enhances beta-catenin-dependent transcription and invasion in squamous cell carcinoma of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(1):65-76.
2008: Raj S Mitra; Mitsuo Goto; Julia S Lee; Diana Maldonado; Jeremy Taylor; Quintin Pan; Thomas Carey; Carol R Bradford; Mark E Prince; Kitrina G Cordell; Keith Lough Kirkwood; Nisha J D'Silva
Rap1GAP promotes invasion via induction of matrix metalloproteinase 9 secretion, which is associated with poor survival in low N-stage squamous cell carcinoma.
Cancer research 2008;68(10):3959-69.
2007: Bradley S Henson; Fei Li; Derek D Coatney; Thomas Carey; Raj S Mitra; Keith Lough Kirkwood; Nisha J D'Silva
An orthotopic floor-of-mouth model for locoregional growth and spread of human squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2007;36(6):363-70.
2006: Zhaocheng Zhang; Raj S Mitra; Bradley S Henson; Nabanita S Datta; Laurie K McCauley; Pawan Kumar; Julia S-J Lee; Thomas Carey; Nisha J D'Silva
Rap1GAP inhibits tumor growth in oropharyngeal squamous cell carcinoma.
The American journal of pathology 2006;168(2):585-96.
2003: Raj S Mitra; Zhaocheng Zhang; Bradley S Henson; David M Kurnit; Thomas Carey; Nisha J D'Silva
Rap1A and rap1B ras-family proteins are prominently expressed in the nucleus of squamous carcinomas: nuclear translocation of GTP-bound active form.
Oncogene 2003;22(40):6243-56.
2003: Nisha J D'Silva; Raj S Mitra; Zhen Zhang; David M Kurnit; C R Babcock; Peter J Polverini; Thomas Carey
Rap1, a small GTP-binding protein is upregulated during arrest of proliferation in human keratinocytes.
Journal of cellular physiology 2003;196(3):532-40.
2001: Raj S Mitra; MA Benedict; D Qian; Kimberly E Foreman; D Ekhterae; Brian J Nickoloff; Gabriel Nuñez
Killing of sarcoma cells by proapoptotic Bcl-X(S): role of the BH3 domain and regulation by Bcl-X(L).
Neoplasia (New York, N.Y.) 2001;3(5):437-45.
2000: Jacques E Nor; Raj S Mitra; M M Sutorik; D J Mooney; Valerie P Castle; Peter J Polverini
Thrombospondin-1 induces endothelial cell apoptosis and inhibits angiogenesis by activating the caspase death pathway.
Journal of vascular research 2000;37(3):209-18.
1997: T Wrone-Smith; Raj S Mitra; Craig Thompson; Rama Jasty; Valerie P Castle; Brian J Nickoloff
Keratinocytes derived from psoriatic plaques are resistant to apoptosis compared with normal skin.
The American journal of pathology 1997;151(5):1321-9.
1997: Raj S Mitra; T Wrone-Smith; PL Simonian; Kimberly E Foreman; Gabriel Nunez; Brian J Nickoloff
Apoptosis in keratinocytes is not dependent on induction of differentiation.
Laboratory investigation; a journal of technical methods and pathology 1997;76(1):99-107.
1996: Kimberly E Foreman; D Trinh; F O Nestle; Raj S Mitra; Brian J Nickoloff
Cultured Kaposi's sarcoma tumor cells fail to stimulate T cell proliferation.
Clinical immunology and immunopathology 1996;78(2):172-9.
1995: Laurence A Turka; RE Goodman; JL Rutkowski; Anders A F Sima; A Merry; Raj S Mitra; T Wrone-Smith; Galen Toews; Robert M Strieter; Brian J Nickoloff
Interleukin 12: a potential link between nerve cells and the immune response in inflammatory disorders.
Molecular medicine (Cambridge, Mass.) 1995;1(6):690-9.
1995: Brian J Nickoloff; Laurence A Turka; Raj S Mitra; F O Nestle
Direct and indirect control of T-cell activation by keratinocytes.
The Journal of investigative dermatology 1995;105(1 Suppl):25S-29S.
1995: Raj S Mitra; T A Judge; F O Nestle; Laurence A Turka; Brian J Nickoloff
Psoriatic skin-derived dendritic cell function is inhibited by exogenous IL-10. Differential modulation of B7-1 (CD80) and B7-2 (CD86) expression.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(6):2668-77.
1994: F O Nestle; Raj S Mitra; C F Bennett; H Chan; Brian J Nickoloff
Cationic lipid is not required for uptake and selective inhibitory activity of ICAM-1 phosphorothioate antisense oligonucleotides in keratinocytes.
The Journal of investigative dermatology 1994;103(4):569-75.
1994: Brian J Nickoloff; Raj S Mitra; James Varani; Xiaodong Huang; Peter J Polverini
Aberrant production of interleukin-8 and thrombospondin-1 by psoriatic keratinocytes mediates angiogenesis.
The American journal of pathology 1994;144(4):820-8.
1993: Brian J Nickoloff; Raj S Mitra; J Green; Yoji Shimizu; Craig Thompson; Laurence A Turka
Activated keratinocytes present bacterial-derived superantigens to T lymphocytes: relevance to psoriasis.
Journal of dermatological science 1993;6(2):127-33.
1993: Raj S Mitra; Y Shimizu; Brian J Nickoloff
Histamine and cis-urocanic acid augment tumor necrosis factor-alpha mediated induction of keratinocyte intercellular adhesion molecule-1 expression.
Journal of cellular physiology 1993;156(2):348-57.
1993: Brian J Nickoloff; Raj S Mitra; K Lee; Laurence A Turka; J Green; Craig Thompson; Yoji Shimizu
Discordant expression of CD28 ligands, BB-1, and B7 on keratinocytes in vitro and psoriatic cells in vivo.
The American journal of pathology 1993;142(4):1029-40.
1993: Brian J Nickoloff; Raj S Mitra; J Green; X G Zheng; Yoji Shimizu; Craig Thompson; Laurence A Turka
Accessory cell function of keratinocytes for superantigens. Dependence on lymphocyte function-associated antigen-1/intercellular adhesion molecule-1 interaction.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(6):2148-59.
1992: Brian J Nickoloff; Raj S Mitra; Yoji Shimizu; J N Barker; G Karabin; T Stoof; Lloyd M Stoolman
HUT 78 T cells bind to noncytokine-stimulated keratinocytes using a non-CD18-dependent adhesion pathway.
The American journal of pathology 1992;140(6):1365-74.
1992: Raj S Mitra; Brian J Nickoloff
Epidermal growth factor and transforming growth factor-alpha decrease gamma interferon receptors and induction of intercellular adhesion molecule (ICAM-1) on cultured keratinocytes.
Journal of cellular physiology 1992;150(2):264-8.
1992: T J Stoof; Raj S Mitra; J Vidya Sarma; Xiaodong Huang; Brian J Nickoloff
Keratinocyte activation following T-lymphocyte binding.
The Journal of investigative dermatology 1992;98(1):92-5.
1991: P L Ribeiro; Raj S Mitra; I A Bernstein
Assessment of the role of DNA damage and repair in the survival of primary cultures of rat cutaneous keratinocytes exposed to bis(2-chloroethyl)sulfide.
Toxicology and applied pharmacology 1991;111(2):342-51.
1991: J N Barker; M L Jones; Raj S Mitra; E Crockett-Torabe; Joseph C Fantone III; Steven Kunkel; Jeffrey S Warren; Xiaodong Huang; Brian J Nickoloff
Modulation of keratinocyte-derived interleukin-8 which is chemotactic for neutrophils and T lymphocytes.
The American journal of pathology 1991;139(4):869-76.
1991: J N Barker; M L Jones; C L Swenson; J Vidya Sarma; Raj S Mitra; Peter A Ward; Kent J Johnson; Joseph C Fantone III; Xiaodong Huang; Brian J Nickoloff
Monocyte chemotaxis and activating factor production by keratinocytes in response to IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(4):1192-7.
1991: J N Barker; Raj S Mitra; Christopher E M Griffiths; Xiaodong Huang; Brian J Nickoloff
Keratinocytes as initiators of inflammation.
Lancet 1991;337(8735):211-4.
1991: B J Nickoloff; James Varani; Raj S Mitra
Modulation of keratinocyte biology by gamma interferon: relevance to cutaneous wound healing.
Progress in clinical and biological research 1991;365():141-54.
1991: Brian J Nickoloff; G D Karabin; J N Barker; Christopher E M Griffiths; J Vidya Sarma; Raj S Mitra; James T Elder; Steven Kunkel; Xiaodong Huang
Cellular localization of interleukin-8 and its inducer, tumor necrosis factor-alpha in psoriasis.
The American journal of pathology 1991;138(1):129-40.
1990: James Varani; J Shayevitz; D Perry; Raj S Mitra; Brian J Nickoloff; John J Voorhees
Retinoic acid stimulation of human dermal fibroblast proliferation is dependent on suboptimal extracellular Ca2+ concentration.
The American journal of pathology 1990;136(6):1275-81.
1990: James Varani; Raj S Mitra; D Gibbs; Sem H Phan; Xiaodong Huang; R Mitra; Timothy S Wang; K J Siebert; Brian J Nickoloff; John J Voorhees
All-trans retinoic acid stimulates growth and extracellular matrix production in growth-inhibited cultured human skin fibroblasts.
The Journal of investigative dermatology 1990;94(5):717-23.
1990: J N Barker; J Vidya Sarma; Raj S Mitra; Xiaodong Huang; Brian J Nickoloff
Marked synergism between tumor necrosis factor-alpha and interferon-gamma in regulation of keratinocyte-derived adhesion molecules and chemotactic factors.
The Journal of clinical investigation 1990;85(2):605-8.
1990: Bruce L Riser; James Varani; Brian J Nickoloff; Raj S Mitra; Xiaodong Huang
Thrombospondin binding by keratinocytes: modulation under conditions which alter thrombospondin biosynthesis.
Dermatologica 1990;180(2):60-5.
1989: Brian J Nickoloff; Raj S Mitra
Inhibition of 125I-epidermal growth factor binding to cultured keratinocytes by antiproliferative molecules gamma interferon, cyclosporin A, and transforming growth factor-beta.
The Journal of investigative dermatology 1989;93(6):799-803.
1989: James Varani; Brian J Nickoloff; Xiaodong Huang; Raj S Mitra; John J Voorhees
All-trans retinoic acid stimulates growth of adult human keratinocytes cultured in growth factor-deficient medium, inhibits production of thrombospondin and fibronectin, and reduces adhesion.
The Journal of investigative dermatology 1989;93(4):449-54.
1989: Brian J Nickoloff; Raj S Mitra; James T Elder; Gary J Fisher; John J Voorhees
Decreased growth inhibition by recombinant gamma interferon is associated with increased transforming growth factor-alpha production in keratinocytes cultured from psoriatic lesions.
The British journal of dermatology 1989;121(2):161-74.
1989: James Varani; Raj S Mitra; B J McClenic; S E Fligiel; D R Inman; Xiaodong Huang; Brian J Nickoloff
Modulation of fibronectin production in normal human melanocytes and malignant melanoma cells by interferon-gamma and tumor necrosis factor-alpha.
The American journal of pathology 1989;134(4):827-36.
1989: B K McClenic; Raj S Mitra; Bruce L Riser; Brian J Nickoloff; Xiaodong Huang; James Varani
Production and utilization of extracellular matrix components by human melanocytes.
Experimental cell research 1989;180(2):314-25.
1988: Brian J Nickoloff; Raj S Mitra; Bruce L Riser; Xiaodong Huang; James Varani
Modulation of keratinocyte motility. Correlation with production of extracellular matrix molecules in response to growth promoting and antiproliferative factors.
The American journal of pathology 1988;132(3):543-51.
1988: Brian J Nickoloff; Bruce L Riser; Raj S Mitra; Xiaodong Huang; James Varani
Inhibitory effect of gamma interferon on cultured human keratinocyte thrombospondin production, distribution, and biologic activities.
The Journal of investigative dermatology 1988;91(3):213-8.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Direct cytopathic effects of cyclosporine A on rapidly proliferating cultured keratinocytes and dermal fibroblasts.
Transplantation proceedings 1988;20(3 Suppl 4):85-90.
1988: James Varani; Brian J Nickoloff; Bruce L Riser; Raj S Mitra; K O'Rourke; Xiaodong Huang
Thrombospondin-induced adhesion of human keratinocytes.
The Journal of clinical investigation 1988;81(5):1537-44.
1988: Brian J Nickoloff; Raj S Mitra
Phorbol ester treatment enhances binding of mononuclear leukocytes to autologous and allogeneic gamma-interferon-treated keratinocytes, which are blocked by anti-LFA-1 monoclonal antibody.
The Journal of investigative dermatology 1988;90(5):684-9.
1988: Brian J Nickoloff; Gary J Fisher; Raj S Mitra; John J Voorhees
Additive and synergistic antiproliferative effects of cyclosporin A and gamma interferon on cultured human keratinocytes.
The American journal of pathology 1988;131(1):12-8.
1985: P L Ribeiro; M C Martinez; Raj S Mitra
A possible correlation between the growth rate and the extent of DNA damage induced by radiodecay in mouse lymphoma cells.
Biochemical and biophysical research communications 1985;128(1):204-10.