Nicholas Mitsiades

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Disorders

Chemicals & Drugs

Anatomy

Cultured Tumor Cells

Physiology

Signal Transduction

Sign-in to see full Profile

Sign-in to see all Coauthors

Publications

TOP 3
Negri Joseph M; McMillin Douglas W; Delmore Jake; Mitsiades Nicholas; Hayden Patrick; Klippel Steffen; Hideshima Teru; Chauhan Dharminder; Munshi Nikhil C; Buser Carolyn A; Pollard John; Richardson Paul G; Anderson Kenneth C; Mitsiades Constantine S
In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465.
Iliaki Eirini; Poulaki Vassiliki; Mitsiades Nicholas; Mitsiades Constantine S; Miller Joan W; Gragoudas Evangelos S
Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy.
Poulaki Vassiliki; Mitsiades Constantine S; Kotoula Vassiliki; Negri Joseph; McMullan Ciaran; Miller Joan W; Marks Paul A; Mitsiades Nicholas
Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Nicholas Mitsiades (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Negri Joseph M; McMillin Douglas W; Delmore Jake; Mitsiades Nicholas; Hayden Patrick; Klippel Steffen; Hideshima Teru; Chauhan Dharminder; Munshi Nikhil C; Buser Carolyn A; Pollard John; Richardson Paul G; Anderson Kenneth C; Mitsiades Constantine S
In vitro anti-myeloma activity of the Aurora kinase inhibitor VE-465.
British journal of haematology 2009;147(5):672-6.
2009: Iliaki Eirini; Poulaki Vassiliki; Mitsiades Nicholas; Mitsiades Constantine S; Miller Joan W; Gragoudas Evangelos S
Role of alpha 4 integrin (CD49d) in the pathogenesis of diabetic retinopathy.
Investigative ophthalmology & visual science 2009;50(10):4898-904.
2009: Poulaki Vassiliki; Mitsiades Constantine S; Kotoula Vassiliki; Negri Joseph; McMullan Ciaran; Miller Joan W; Marks Paul A; Mitsiades Nicholas
Molecular sequelae of histone deacetylase inhibition in human retinoblastoma cell lines: clinical implications.
Investigative ophthalmology & visual science 2009;50(9):4072-9.
2009: McMillin Douglas W; Ooi Melissa; Delmore Jake; Negri Joseph; Hayden Patrick; Mitsiades Nicolas; Jakubikova Jana; Maira Sauveur-Michel; Garcia-Echeverria Carlos; Schlossman Robert; Munshi Nikhil C; Richardson Paul G; Anderson Kenneth C; Mitsiades Constantine S
Antimyeloma activity of the orally bioavailable dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor NVP-BEZ235.
Cancer research 2009;69(14):5835-42.
2009: Kotoula Vassiliki; Sozopoulos Elias; Litsiou Helen; Fanourakis Galinos; Koletsa Triantafyllia; Voutsinas Gerassimos; Tseleni-Balafouta Sophia; Mitsiades Constantine S; Wellmann Axel; Mitsiades Nicholas
Mutational analysis of the BRAF, RAS and EGFR genes in human adrenocortical carcinomas.
Endocrine-related cancer 2009;16(2):565-72.
2008: Mitsiades Constantine S; Ocio Enrique M; Pandiella Atanasio; Maiso Patricia; Gajate Consuelo; Garayoa Mercedes; Vilanova David; Montero Juan Carlos; Mitsiades Nicholas; McMullan Ciaran J; Munshi Nikhil C; Hideshima Teru; Chauhan Dharminder; Aviles Pablo; Otero Gabriel; Faircloth Glynn; Mateos M Victoria; Richardson Paul G; Mollinedo Faustino; San-Miguel Jesus F; Anderson Kenneth C
Aplidin, a marine organism-derived compound with potent antimyeloma activity in vitro and in vivo.
Cancer research 2008;68(13):5216-25.
2008: Williams Catherine J; Mitsiades Nicholas; Sozopoulos Elias; Hsi Alex; Wolk Alicja; Nifli Artemissia-Phoebe; Tseleni-Balafouta Sofia; Mantzoros Christos S
Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.
Endocrine-related cancer 2008;15(1):289-99.
2007: Mitsiades Constantine S; Hayden Patrick; Kotoula Vassiliki; McMillin Douglas W; McMullan Ciaran; Negri Joseph; Delmore Jake E; Poulaki Vassiliki; Mitsiades Nicholas
Bcl-2 overexpression in thyroid carcinoma cells increases sensitivity to Bcl-2 homology 3 domain inhibition.
The Journal of clinical endocrinology and metabolism 2007;92(12):4845-52.
2007: Poulaki Vassiliki; Mitsiades Constantine S; Kotoula Vassiliki; Negri Joseph; McMillin Douglas; Miller Joan W; Mitsiades Nicholas
The proteasome inhibitor bortezomib induces apoptosis in human retinoblastoma cell lines in vitro.
Investigative ophthalmology & visual science 2007;48(10):4706-19.
2007: Mitsiades Constantine S; Mitsiades Nicholas S; Richardson Paul G; Munshi Nikhil C; Anderson Kenneth C
Multiple myeloma: a prototypic disease model for the characterization and therapeutic targeting of interactions between tumor cells and their local microenvironment.
Journal of cellular biochemistry 2007;101(4):950-68.
2007: Poulaki Vassiliki; Iliaki Eirini; Mitsiades Nicholas; Mitsiades Constantine S; Paulus Yiannis N; Bula Deisy V; Gragoudas Evangelos S; Miller Joan W
Inhibition of Hsp90 attenuates inflammation in endotoxin-induced uveitis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(9):2113-23.
2007: Mitsiades Constantine S; Negri Joseph; McMullan Ciaran; McMillin Douglas W; Sozopoulos Elias; Fanourakis Galinos; Voutsinas Gerassimos; Tseleni-Balafouta Sophia; Poulaki Vassiliki; Batt David; Mitsiades Nicholas
Targeting BRAFV600E in thyroid carcinoma: therapeutic implications.
Molecular cancer therapeutics 2007;6(3):1070-8.
2007: Chauhan Dharminder; Neri Paola; Velankar Mugdha; Podar Klaus; Hideshima Teru; Fulciniti Mariateresa; Tassone Pierfrancesco; Raje Noopur; Mitsiades Constantine; Mitsiades Nicholas; Richardson Paul; Zawel Leigh; Tran Mary; Munshi Nikhil; Anderson Kenneth C
Targeting mitochondrial factor Smac/DIABLO as therapy for multiple myeloma (MM).
Blood 2007;109(3):1220-7.
2006: Mitsiades Constantine S; Mitsiades Nicholas; Hideshima Teru; Richardson Paul G; Anderson Kenneth C
Proteasome inhibition as a new therapeutic principle in hematological malignancies.
Current drug targets 2006;7(10):1341-7.
2006: Mitsiades Constantine S; McMillin Douglas; Kotoula Vassiliki; Poulaki Vassiliki; McMullan Ciaran; Negri Joseph; Fanourakis Galinos; Tseleni-Balafouta Sophia; Ain Kenneth B; Mitsiades Nicholas
Antitumor effects of the proteasome inhibitor bortezomib in medullary and anaplastic thyroid carcinoma cells in vitro.
The Journal of clinical endocrinology and metabolism 2006;91(10):4013-21.
2006: Mitsiades Constantine S; Kotoula Vassiliki; Poulaki Vassiliki; Sozopoulos Elias; Negri Joseph; Charalambous Elpida; Fanourakis Galinos; Voutsinas Gerassimos; Tseleni-Balafouta Sophia; Mitsiades Nicholas
Epidermal growth factor receptor as a therapeutic target in human thyroid carcinoma: mutational and functional analysis.
The Journal of clinical endocrinology and metabolism 2006;91(9):3662-6.
2006: Mitsiades Constantine S; Mitsiades Nicholas S; Munshi Nikhil C; Richardson Paul G; Anderson Kenneth C
The role of the bone microenvironment in the pathophysiology and therapeutic management of multiple myeloma: interplay of growth factors, their receptors and stromal interactions.
European journal of cancer (Oxford, England : 1990) 2006;42(11):1564-73.
2006: Mitsiades Constantine S; Poulaki Vassiliki; Fanourakis Galinos; Sozopoulos Elias; McMillin Douglas; Wen Zhaoqin; Voutsinas Gerassimos; Tseleni-Balafouta Sophia; Mitsiades Nicholas
Fas signaling in thyroid carcinomas is diverted from apoptosis to proliferation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(12):3705-12.
2006: Mitsiades Constantine S; Mitsiades Nicholas S; McMullan Ciaran J; Poulaki Vassiliki; Kung Andrew L; Davies Faith E; Morgan Gareth; Akiyama Masaharu; Shringarpure Reshma; Munshi Nikhil C; Richardson Paul G; Hideshima Teru; Chauhan Dharminder; Gu Xuesong; Bailey Charles; Joseph Marie; Libermann Towia A; Rosen Neal S; Anderson Kenneth C
Antimyeloma activity of heat shock protein-90 inhibition.
Blood 2006;107(3):1092-100.
2005: Chauhan Dharminder; Catley Laurence; Li Guilan; Podar Klaus; Hideshima Teru; Velankar Mugdha; Mitsiades Constantine; Mitsiades Nicolas; Yasui Hiroshi; Letai Anthony; Ovaa Huib; Berkers Celia; Nicholson Benjamin; Chao Ta-Hsiang; Neuteboom Saskia T C; Richardson Paul; Palladino Michael A; Anderson Kenneth C
A novel orally active proteasome inhibitor induces apoptosis in multiple myeloma cells with mechanisms distinct from Bortezomib.
Cancer cell 2005;8(5):407-19.
2005: Chauhan Dharminder; Li Guilan; Podar Klaus; Hideshima Teru; Neri Paola; He Deli; Mitsiades Nicholas; Richardson Paul; Chang Yan; Schindler Joanne; Carver Bradley; Anderson Kenneth C
A novel carbohydrate-based therapeutic GCS-100 overcomes bortezomib resistance and enhances dexamethasone-induced apoptosis in multiple myeloma cells.
Cancer research 2005;65(18):8350-8.
2005: Mitsiades Constantine S; Mitsiades Nicholas; Hideshima Teru; Richardson Paul G; Anderson Kenneth C
Proteasome inhibition as a therapeutic strategy for hematologic malignancies.
Expert review of anticancer therapy 2005;5(3):465-76.
2005: Mitsiades Constantine S; Poulaki Vassiliki; McMullan Ciaran; Negri Joseph; Fanourakis Galinos; Goudopoulou Athina; Richon Victoria M; Marks Paul A; Mitsiades Nicholas
Novel histone deacetylase inhibitors in the treatment of thyroid cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(10):3958-65.
2005: Poulaki Vassiliki; Mitsiades Constantine S; McMullan Ciaran; Fanourakis Galinos; Negri Joseph; Goudopoulou Athina; Halikias Ioannis X; Voutsinas Gerassimos; Tseleni-Balafouta Sophia; Miller Joan W; Mitsiades Nicholas
Human retinoblastoma cells are resistant to apoptosis induced by death receptors: role of caspase-8 gene silencing.
Investigative ophthalmology & visual science 2005;46(1):358-66.
2005: Mitsiades Constantine S; Mitsiades Nicholas; Hideshima Teru; Richardson Paul G; Anderson Kenneth C
Proteasome inhibitors as therapeutics.
Essays in biochemistry 2005;41():205-18.
2004: Mitsiades Constantine S; Mitsiades Nicholas; Munshi Nikhil C; Anderson Kenneth C
Focus on multiple myeloma.
Cancer cell 2004;6(5):439-44.
2004: Poulaki Vassiliki; Joussen Antonia M; Mitsiades Nicholas; Mitsiades Constantine S; Iliaki Eirini F; Adamis Anthony P
Insulin-like growth factor-I plays a pathogenetic role in diabetic retinopathy.
The American journal of pathology 2004;165(2):457-69.
2004: Mitsiades Constantine S; Mitsiades Nicholas; Koutsilieris Michael
The Akt pathway: molecular targets for anti-cancer drug development.
Current cancer drug targets 2004;4(3):235-56.
2004: Poulaki Vassiliki; Mitsiades Nicholas; Kruse Friedrich E; Radetzky Sven; Iliaki Eirini; Kirchhof Bernd; Joussen Antonia M
Activin a in the regulation of corneal neovascularization and vascular endothelial growth factor expression.
The American journal of pathology 2004;164(4):1293-302.
2004: Mitsiades Constantine S; Mitsiades Nicholas S; McMullan Ciaran J; Poulaki Vassiliki; Shringarpure Reshma; Akiyama Masaharu; Hideshima Teru; Chauhan Dharminder; Joseph Marie; Libermann Towia A; García-Echeverría Carlos; Pearson Mark A; Hofmann Francesco; Anderson Kenneth C; Kung Andrew L
Inhibition of the insulin-like growth factor receptor-1 tyrosine kinase activity as a therapeutic strategy for multiple myeloma, other hematologic malignancies, and solid tumors.
Cancer cell 2004;5(3):221-30.
2004: Chauhan D; Li G; Auclair D; Hideshima T; Podar K; Mitsiades N; Mitsiades C; Chen L B; Munshi N; Saxena S; Anderson K C
2-Methoxyestardiol and bortezomib/proteasome-inhibitor overcome dexamethasone-resistance in multiple myeloma cells by modulating Heat Shock Protein-27.
Apoptosis : an international journal on programmed cell death 2004;9(2):149-55.
2004: LeBlanc Richard; Hideshima Teru; Catley Laurence P; Shringarpure Reshma; Burger Renate; Mitsiades Nicholas; Mitsiades Constantine; Cheema Puneet; Chauhan Dharminder; Richardson Paul G; Anderson Kenneth C; Munshi Nikhil C
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway.
Blood 2004;103(5):1787-90.
2004: Munshi Nikhil C; Hideshima Teru; Carrasco Daniel; Shammas Masood; Auclair Daniel; Davies Faith; Mitsiades Nicholas; Mitsiades Constantine; Kim Ryung Suk; Li Cheng; Rajkumar S Vincent; Fonseca Rafael; Bergsagel Lief; Chauhan Dharminder; Anderson Kenneth C
Identification of genes modulated in multiple myeloma using genetically identical twin samples.
Blood 2004;103(5):1799-806.
2004: Mitsiades Constantine S; Mitsiades Nicholas S; McMullan Ciaran J; Poulaki Vassiliki; Shringarpure Reshma; Hideshima Teru; Akiyama Masaharu; Chauhan Dharminder; Munshi Nikhil; Gu Xuesong; Bailey Charles; Joseph Marie; Libermann Towia A; Richon Victoria M; Marks Paul A; Anderson Kenneth C
Transcriptional signature of histone deacetylase inhibition in multiple myeloma: biological and clinical implications.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(2):540-5.
2003: Hideshima Teru; Chauhan Dharminder; Hayashi Toshiaki; Podar Klaus; Akiyama Masaharu; Mitsiades Constantine; MItsiades Nicholas; Gong Baoqing; Bonham Lynn; de Vries Peter; Munshi Nikhil; Richardson Paul G; Singer Jack W; Anderson Kenneth C
Antitumor activity of lysophosphatidic acid acyltransferase-beta inhibitors, a novel class of agents, in multiple myeloma.
Cancer research 2003;63(23):8428-36.
2003: Davies Faith E; Dring Ann M; Li Cheng; Rawstron Andrew C; Shammas Masood A; O'Connor Sheila M; Fenton James A L; Hideshima Teru; Chauhan Dharminder; Tai Isabella T; Robinson Elizabeth; Auclair Daniel; Rees Karen; Gonzalez David; Ashcroft A John; Dasgupta Ranjit; Mitsiades Constantine; Mitsiades Nicholas; Chen Lan B; Wong Wing H; Munshi Nikhil C; Morgan Gareth J; Anderson Kenneth C
Insights into the multistep transformation of MGUS to myeloma using microarray expression analysis.
Blood 2003;102(13):4504-11.
2003: Hideshima Teru; Chauhan Dharminder; Hayashi Toshiaki; Akiyama Masaharu; Mitsiades Nicholas; Mitsiades Constantine; Podar Klaus; Munshi Nikhil C; Richardson Paul G; Anderson Kenneth C
Proteasome inhibitor PS-341 abrogates IL-6 triggered signaling cascades via caspase-dependent downregulation of gp130 in multiple myeloma.
Oncogene 2003;22(52):8386-93.
2003: Poulaki Vassiliki; Mitsiades Constantine S; McMullan Ciaran; Sykoutri Despoina; Fanourakis Galinos; Kotoula Vassiliki; Tseleni-Balafouta Sophia; Koutras Demetrios A; Mitsiades Nicholas
Regulation of vascular endothelial growth factor expression by insulin-like growth factor I in thyroid carcinomas.
The Journal of clinical endocrinology and metabolism 2003;88(11):5392-8.
2003: Chauhan Dharminder; Li Guilan; Hideshima Teru; Podar Klaus; Mitsiades Constantine; Mitsiades Nicholas; Catley Laurence; Tai Yu Tzu; Hayashi Toshiaki; Shringarpure Reshma; Burger Renate; Munshi Nikhil; Ohtake Yasuyuki; Saxena Satya; Anderson Kenneth C
Hsp27 inhibits release of mitochondrial protein Smac in multiple myeloma cells and confers dexamethasone resistance.
Blood 2003;102(9):3379-86.
2003: Mitsiades Constantine S; Mitsiades Nicholas S; Bronson Ron T; Chauhan Dharminder; Munshi Nikhil; Treon Steven P; Maxwell Christopher A; Pilarski Linda; Hideshima Teru; Hoffman Robert M; Anderson Kenneth C
Fluorescence imaging of multiple myeloma cells in a clinically relevant SCID/NOD in vivo model: biologic and clinical implications.
Cancer research 2003;63(20):6689-96.
2003: Mitsiades Constantine S; Sykoutri Despoina; McMullan Ciaran; Poulaki Vassiliki; Mitsiades Nicholas
Effect of imatinib mesylate (Gleevec) on anaplastic thyroid carcinoma cell lines.
The Journal of clinical endocrinology and metabolism 2003;88(10):5043-4; author reply 5044.
2003: Catley Laurence; Weisberg Ellen; Tai Yu-Tzu; Atadja Peter; Remiszewski Stacy; Hideshima Teru; Mitsiades Nicholas; Shringarpure Reshma; LeBlanc Richard; Chauhan Dharminder; Munshi Nikhil C; Schlossman Robert; Richardson Paul; Griffin James; Anderson Kenneth C
NVP-LAQ824 is a potent novel histone deacetylase inhibitor with significant activity against multiple myeloma.
Blood 2003;102(7):2615-22.
2003: Tai Yu-Tzu; Podar Klaus; Catley Laurence; Tseng Yu-Hua; Akiyama Masaharu; Shringarpure Reshma; Burger Renate; Hideshima Teru; Chauhan Dharminder; Mitsiades Nicholas; Richardson Paul; Munshi Nikhil C; Kahn C Ronald; Mitsiades Constantine; Anderson Kenneth C
Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.
Cancer research 2003;63(18):5850-8.
2003: Mitsiades C S; Poulaki V; Mitsiades N
The role of apoptosis-inducing receptors of the tumor necrosis factor family in thyroid cancer.
The Journal of endocrinology 2003;178(2):205-16.
2003: Chauhan Dharminder; Li Guilan; Hideshima Teru; Podar Klaus; Mitsiades Constantine; Mitsiades Nicholas; Munshi Nikhil; Kharbanda Surender; Anderson Kenneth C
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells.
The Journal of biological chemistry 2003;278(20):17593-6.
2003: Mitsiades Nicholas; Mitsiades Constantine S; Richardson Paul G; McMullan Ciaran; Poulaki Vassiliki; Fanourakis Galinos; Schlossman Robert; Chauhan Dharminder; Munshi Nikhil C; Hideshima Teru; Richon Victoria M; Marks Paul A; Anderson Kenneth C
Molecular sequelae of histone deacetylase inhibition in human malignant B cells.
Blood 2003;101(10):4055-62.
2003: Chauhan Dharminder; Li Guilan; Auclair Daniel; Hideshima Teru; Richardson Paul; Podar Klaus; Mitsiades Nicholas; Mitsiades Constantine; Li Cheng; Kim Ryung Suk; Munshi Nikhil; Chen Lan Bo; Wong Wing; Anderson Kenneth C
Identification of genes regulated by 2-methoxyestradiol (2ME2) in multiple myeloma cells using oligonucleotide arrays.
Blood 2003;101(9):3606-14.
2003: Mitsiades Constantine S; Mitsiades Nicholas; Richardson Paul G; Treon Steven P; Anderson Kenneth C
Novel biologically based therapies for Waldenstrom's macroglobulinemia.
Seminars in oncology 2003;30(2):309-12.
2003: Treon Steven P; Kelliher Abigail; Keele Beverly; Frankel Stanley; Emmanouilides Christos; Kimby Eva; Schlossman Robert; Mitsiades Nicholas; Mitsiades Constantine; Preffer Frederic; Anderson Kenneth C
Expression of serotherapy target antigens in Waldenstrom's macroglobulinemia: therapeutic applications and considerations.
Seminars in oncology 2003;30(2):248-52.
2003: Mitsiades Constantine S; Mitsiades Nicholas; Treon Steven P; Anderson Kenneth C
Proteomic analyses in Waldenstrom's macroglobulinemia and other plasma cell dyscrasias.
Seminars in oncology 2003;30(2):156-60.
2003: Tai Yu-Tzu; Podar Klaus; Mitsiades Nicholas; Lin Boris; Mitsiades Constantine; Gupta Deepak; Akiyama Masaharu; Catley Laurence; Hideshima Teru; Munshi Nikhil C; Treon Steven P; Anderson Kenneth C
CD40 induces human multiple myeloma cell migration via phosphatidylinositol 3-kinase/AKT/NF-kappa B signaling.
Blood 2003;101(7):2762-9.
2003: Mitsiades Nicholas; Mitsiades Constantine S; Richardson Paul G; Poulaki Vassiliki; Tai Yu-Tzu; Chauhan Dharminder; Fanourakis Galinos; Gu Xuesong; Bailey Charles; Joseph Marie; Libermann Towia A; Schlossman Robert; Munshi Nikhil C; Hideshima Teru; Anderson Kenneth C
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications.
Blood 2003;101(6):2377-80.
2003: Podar Klaus; Tai Yu-Tzu; Cole Craig E; Hideshima Teru; Sattler Martin; Hamblin Angela; Mitsiades Nicholas; Schlossman Robert L; Davies Faith E; Morgan Gareth J; Munshi Nikhil C; Chauhan Dharminder; Anderson Kenneth C
Essential role of caveolae in interleukin-6- and insulin-like growth factor I-triggered Akt-1-mediated survival of multiple myeloma cells.
The Journal of biological chemistry 2003;278(8):5794-801.
2003: Hideshima Teru; Mitsiades Constantine; Akiyama Masaharu; Hayashi Toshiaki; Chauhan Dharminder; Richardson Paul; Schlossman Robert; Podar Klaus; Munshi Nikhil C; Mitsiades Nicholas; Anderson Kenneth C
Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341.
Blood 2003;101(4):1530-4.
2003: Akiyama Masaharu; Hideshima Teru; Hayashi Toshiaki; Tai Yu-Tzu; Mitsiades Constantine S; Mitsiades Nicholas; Chauhan Dharminder; Richardson Paul; Munshi Nikhil C; Anderson Kenneth C
Nuclear factor-kappaB p65 mediates tumor necrosis factor alpha-induced nuclear translocation of telomerase reverse transcriptase protein.
Cancer research 2003;63(1):18-21.
2003: Joussen Antonia M; Poulaki Vassiliki; Mitsiades Nicholas; Stechschulte Stephen U; Kirchhof Bernd; Dartt Darlene A; Fong Guo-Hua; Rudge John; Wiegand Stanley J; Yancopoulos George D; Adamis Anthony P
VEGF-dependent conjunctivalization of the corneal surface.
Investigative ophthalmology & visual science 2003;44(1):117-23.
2003: Joussen Antonia M; Poulaki Vassiliki; Mitsiades Nicholas; Cai Wen-yi; Suzuma Izumi; Pak John; Ju Shyr-Te; Rook Susan L; Esser Peter; Mitsiades Constantin S; Kirchhof Bernd; Adamis Anthony P; Aiello Lloyd Paul
Suppression of Fas-FasL-induced endothelial cell apoptosis prevents diabetic blood-retinal barrier breakdown in a model of streptozotocin-induced diabetes.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(1):76-8.
2002: Poulaki Vassiliki; Mitsiades Constantine S; Joussen Antonia M; Lappas Alexandra; Kirchhof Bernd; Mitsiades Nicholas
Constitutive nuclear factor-kappaB activity is crucial for human retinoblastoma cell viability.
The American journal of pathology 2002;161(6):2229-40.
2002: Mitsiades Nicholas; Mitsiades Constantine S; Poulaki Vassiliki; Chauhan Dharminder; Fanourakis Galinos; Gu Xuesong; Bailey Charles; Joseph Marie; Libermann Towia A; Treon Steven P; Munshi Nikhil C; Richardson Paul G; Hideshima Teru; Anderson Kenneth C
Molecular sequelae of proteasome inhibition in human multiple myeloma cells.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14374-9.
2002: LeBlanc Richard; Catley Laurence P; Hideshima Teru; Lentzsch Suzanne; Mitsiades Constantine S; Mitsiades Nicholas; Neuberg Donna; Goloubeva Olga; Pien Christine S; Adams Julian; Gupta Deepak; Richardson Paul G; Munshi Nikhil C; Anderson Kenneth C
Proteasome inhibitor PS-341 inhibits human myeloma cell growth in vivo and prolongs survival in a murine model.
Cancer research 2002;62(17):4996-5000.
2002: Mitsiades Constantine S; Mitsiades Nicholas; Poulaki Vassiliki; Schlossman Robert; Akiyama Masaharu; Chauhan Dharminder; Hideshima Teru; Treon Steven P; Munshi Nikhil C; Richardson Paul G; Anderson Kenneth C
Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
Oncogene 2002;21(37):5673-83.
2002: Poulaki Vassiliki; Mitsiades Constantine S; Kotoula Vassiliki; Tseleni-Balafouta Sophia; Ashkenazi Avi; Koutras Demetrios A; Mitsiades Nicholas
Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells.
The American journal of pathology 2002;161(2):643-54.
2002: Gupta Deepak; Podar Klaus; Tai Yu Tzu; Lin Boris; Hideshima Teru; Akiyama Masaharu; LeBlanc Richard; Catley Laurence; Mitsiades Nicholas; Mitsiades Constantine; Chauhan Dharminder; Munshi Nikhil C; Anderson Kenneth C
beta-lapachone, a novel plant product, overcomes drug resistance in human multiple myeloma cells.
Experimental hematology 2002;30(7):711-20.
2002: Akiyama Masaharu; Hideshima Teru; Hayashi Toshiaki; Tai Yu-Tzu; Mitsiades Constantine S; Mitsiades Nicholas; Chauhan Dharminder; Richardson Paul; Munshi Nikhil C; Anderson Kenneth C
Cytokines modulate telomerase activity in a human multiple myeloma cell line.
Cancer research 2002;62(13):3876-82.
2002: Mitsiades Nicholas; Mitsiades Constantine S; Poulaki Vassiliki; Chauhan Dharminder; Richardson Paul G; Hideshima Teru; Munshi Nikhil C; Treon Steven P; Anderson Kenneth C
Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: therapeutic implications.
Blood 2002;99(12):4525-30.
2002: Mitsiades Nicholas; Mitsiades Constantine S; Poulaki Vassiliki; Chauhan Dharminder; Richardson Paul G; Hideshima Teru; Munshi Nikhil; Treon Steven P; Anderson Kenneth C
Biologic sequelae of nuclear factor-kappaB blockade in multiple myeloma: therapeutic applications.
Blood 2002;99(11):4079-86.
2002: Hideshima Teru; Chauhan Dharminder; Richardson Paul; Mitsiades Constantine; Mitsiades Nicholas; Hayashi Toshiaki; Munshi Nikhil; Dang Lenny; Castro Alfredo; Palombella Vito; Adams Julian; Anderson Kenneth C
NF-kappa B as a therapeutic target in multiple myeloma.
The Journal of biological chemistry 2002;277(19):16639-47.
2002: Mitsiades Nicholas; Mitsiades Constantine S; Poulaki Vassiliki; Anderson Kenneth C; Treon Steven P
Intracellular regulation of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human multiple myeloma cells.
Blood 2002;99(6):2162-71.
2002: Joussen Antonia M; Poulaki Vassiliki; Mitsiades Nicholas; Kirchhof Bernd; Koizumi Kan; Döhmen Sven; Adamis Anthony P
Nonsteroidal anti-inflammatory drugs prevent early diabetic retinopathy via TNF-alpha suppression.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(3):438-40.
2002: Joussen Antonia M; Poulaki Vassiliki; Qin Wenying; Kirchhof Bernd; Mitsiades Nicholas; Wiegand Stanley J; Rudge John; Yancopoulos George D; Adamis Anthony P
Retinal vascular endothelial growth factor induces intercellular adhesion molecule-1 and endothelial nitric oxide synthase expression and initiates early diabetic retinal leukocyte adhesion in vivo.
The American journal of pathology 2002;160(2):501-9.
2002: Treon Steven P; Pilarski Linda M; Belch Andrew R; Kelliher Abigail; Preffer Frederic I; Shima Yoshihito; Mitsiades Constantine S; Mitsiades Nicholas S; Szczepek Agnieszka J; Ellman Leonard; Harmon David; Grossbard Michael L; Anderson Kenneth C
CD20-directed serotherapy in patients with multiple myeloma: biologic considerations and therapeutic applications.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2002;25(1):72-81.
2001: Mitsiades N; Poulaki V; Mitsiades C S; Koutras D A; Chrousos G P
Apoptosis induced by FasL and TRAIL/Apo2L in the pathogenesis of thyroid diseases.
Trends in endocrinology and metabolism: TEM 2001;12(9):384-90.
2001: Poulaki V; Mitsiades C S; Mitsiades N
The role of Fas and FasL as mediators of anticancer chemotherapy.
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2001;4(4):233-42.
2001: Mitsiades N; Mitsiades C S; Poulaki V; Anderson K C; Treon S P
Concepts in the use of TRAIL/Apo2L: an emerging biotherapy for myeloma and other neoplasias.
Expert opinion on investigational drugs 2001;10(8):1521-30.
2001: Mitsiades C S; Treon S P; Mitsiades N; Shima Y; Richardson P; Schlossman R; Hideshima T; Anderson K C
TRAIL/Apo2L ligand selectively induces apoptosis and overcomes drug resistance in multiple myeloma: therapeutic applications.
Blood 2001;98(3):795-804.
2001: Mitsiades N; Poulaki V; Mitsiades C S; Anderson K C
Induction of tumour cell apoptosis by matrix metalloproteinase inhibitors: new tricks from a (not so) old drug.
Expert opinion on investigational drugs 2001;10(6):1075-84.
2001: Poulaki V; Mitsiades N; Romero M E; Tsokos M
Fas-mediated apoptosis in neuroblastoma requires mitochondrial activation and is inhibited by FLICE inhibitor protein and Bcl-2.
Cancer research 2001;61(12):4864-72.
2001: Leone A; Mitsiades N; Ward Y; Spinelli B; Poulaki V; Tsokos M; Kelly K
The Gem GTP-binding protein promotes morphological differentiation in neuroblastoma.
Oncogene 2001;20(25):3217-25.
2001: Treon S P; Mitsiades C; Mitsiades N; Young G; Doss D; Schlossman R; Anderson K C
Tumor cell expression of CD59 is associated with resistance to CD20 serotherapy in patients with B-cell malignancies.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2001;24(3):263-71.
2001: Mitsiades N; Poulaki V; Mitsiades C; Tsokos M
Ewing's sarcoma family tumors are sensitive to tumor necrosis factor-related apoptosis-inducing ligand and express death receptor 4 and death receptor 5.
Cancer research 2001;61(6):2704-12.
2001: Mitsiades N; Yu W H; Poulaki V; Tsokos M; Stamenkovic I
Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity.
Cancer research 2001;61(2):577-81.
2000: Marinò M; Chiovato L; Mitsiades N; Latrofa F; Andrews D; Tseleni-Balafouta S; Collins A B; Pinchera A; McCluskey R T
Circulating thyroglobulin transcytosed by thyroid cells in complexed with secretory components of its endocytic receptor megalin.
The Journal of clinical endocrinology and metabolism 2000;85(9):3458-67.
2000: Mitsiades N; Poulaki V; Tseleni-Balafouta S; Koutras D A; Stamenkovic I
Thyroid carcinoma cells are resistant to FAS-mediated apoptosis but sensitive to tumor necrosis factor-related apoptosis-inducing ligand.
Cancer research 2000;60(15):4122-9.
1999: Mitsiades N; Poulaki V; Leone A; Tsokos M
Fas-mediated apoptosis in Ewing's sarcoma cell lines by metalloproteinase inhibitors.
Journal of the National Cancer Institute 1999;91(19):1678-84.
1999: Mitsiades N; Poulaki V; Mastorakos G; Tseleni-Balafouta S T; Kotoula V; Koutras D A; Tsokos M
Fas ligand expression in thyroid carcinomas: a potential mechanism of immune evasion.
The Journal of clinical endocrinology and metabolism 1999;84(8):2924-32.
1998: Mitsiades N; Poulaki V; Kotoula V; Leone A; Tsokos M
Fas ligand is present in tumors of the Ewing's sarcoma family and is cleaved into a soluble form by a metalloproteinase.
The American journal of pathology 1998;153(6):1947-56.
1998: Mitsiades N; Poulaki V; Kotoula V; Mastorakos G; Tseleni-Balafouta S; Koutras D A; Tsokos M
Fas/Fas ligand up-regulation and Bcl-2 down-regulation may be significant in the pathogenesis of Hashimoto's thyroiditis.
The Journal of clinical endocrinology and metabolism 1998;83(6):2199-203.
1996: Stratakis C A; Mitsiades N S; Chrousos G P; Margioris A N
Dopamine affects the in vitro basal secretion of rat placenta opioids in an opioid and dopamine receptor type-specific manner.
European journal of pharmacology 1996;315(1):53-8.
1995: Stratakis C A; Mitsiades N S; Sun D; Chrousos G P; O'Connell A
Recurring oral giant cell lesion in a child with X-linked hypophosphatemic rickets: clinical manifestation of occult parathyroidism?
The Journal of pediatrics 1995;127(3):444-6.

Sign-in to see more

Sign-in free and Explore the Exciting World of BiomedExperts:

NetworkView

Nicholas Mitsiades

Research Profile (preview)

Disorders

Chemicals & Drugs

Anatomy

Physiology

Network (preview)

Publications

Sign in free and see...

Visualized networks:

GeoTargeted Searches:

Research Profiles:

Geonetwork of Nicholas Mitsiades (preview)

All Publications