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Thimios Mitsiadis

Research Profile

Living Beings

Mouse

Physiology

Anatomy

Chemicals & Drugs

Procedures

In Situ Hybridization

Disorders

Tooth Injuries

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Publications

TOP 3
Thaleia Kouskoura; Anastasiia Kozlova; Thimios A Mitsiadis; Vasiliki Zouvelou; Maria Alexiou; Susanne Blumer; Matthias Chiquet; Christos Katsaros; Daniel Graf
The etiology of cleft palate formation in BMP7-deficient mice.
Thimios A Mitsiadis; Anna Woloszyk; Lucia Jiménez-Rojo
Nanodentistry: combining nanostructured materials and stem cells for dental tissue regeneration.
Chun-Ying Li; Hans-Ulrich Luder; Martin McMahon; Thimios A Mitsiadis; Wanghee Cha; Roch-Philippe Charles; Ophir D Klein
E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor.

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All Publications

2013: Thaleia Kouskoura; Anastasiia Kozlova; Thimios A Mitsiadis; Vasiliki Zouvelou; Maria Alexiou; Susanne Blumer; Matthias Chiquet; Christos Katsaros; Daniel Graf
The etiology of cleft palate formation in BMP7-deficient mice.
PloS one 2013;8(3):e59463.
2012: Thimios A Mitsiadis; Anna Woloszyk; Lucia Jiménez-Rojo
Nanodentistry: combining nanostructured materials and stem cells for dental tissue regeneration.
Nanomedicine (London, England) 2012;7(11):1743-53.
2012: Chun-Ying Li; Hans-Ulrich Luder; Martin McMahon; Thimios A Mitsiadis; Wanghee Cha; Roch-Philippe Charles; Ophir D Klein
E-cadherin regulates the behavior and fate of epithelial stem cells and their progeny in the mouse incisor.
Developmental biology 2012;366(2):357-66.
2012: C Schiraldi; A Stellavato; V Tirino; A Woloszyk; A D'Agostino; Riccardo D'Aquino; Alfredo De Rosa; L Laino; Gianpaolo Papaccio; Thimios A Mitsiadis
Fighting for territories: time-lapse analysis of dental pulp and dental follicle stem cells in co-culture reveals specific migratory capabilities.
European cells & materials 2012;24():426-40.
2012: Javier Catón; Thimios A Mitsiadis; Peter R Morgan
In vitro studies on odontogenic tumors.
Methods in molecular biology (Clifton, N.J.) 2012;887():167-77.
2012: Lucía Jiménez-Rojo; Daniel Graf; Zoraide Granchi; Thimios A Mitsiadis
Stem Cell Fate Determination during Development and Regeneration of Ectodermal Organs.
Frontiers in physiology 2012;3():107.
2012: Aikaterini Segklia; Eve Seuntjens; Elke Stappers; Sotiris Tsalavos; Maximilianos Elkouris; Danny Huylebroeck; Thimios A Mitsiadis; Eumorphia Remboutsika; Daniel Graf
Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse.
PloS one 2012;7(3):e34088.
2011: Eva Lana-Elola; Frank P Luyten; Thimios A Mitsiadis; Ritva Rice; Maarit Takatalo; Przemko Tylzanowski; Lotta Veistinen; Kirsi Alakurtti; Daniel Graf; David P Rice
Noggin null allele mice exhibit a microform of holoprosencephaly.
Human molecular genetics 2011;20(20):4005-15.
2011: Thimios A Mitsiadis; Hans-Ulrich Luder
Genetic basis for tooth malformations: from mice to men and back again.
Clinical genetics 2011;80(4):319-29.
2011: Thimios A Mitsiadis; G Papaccio; A Feki; J Catón
Dental pulp stem cells, niches, and notch signaling in tooth injury.
Advances in dental research 2011;23(3):275-9.
2011: Thimios A Mitsiadis; Petros Papagerakis
Regenerated teeth: the future of tooth replacement?
Regenerative medicine 2011;6(2):135-9.
2011: I Grad; Y Hibaoui; Outi Hovatta; Marisa E Jaconi; J Kere; Thimios A Mitsiadis; M F Pelte; M R Sailani; Virpi Töhönen; M Zucchelli; S E Antonarakis; R Bergström-Tengzelius; S Bouillaguet; Laurie Chicha; Sophie Dahoun; Anis Feki
NANOG priming before full reprogramming may generate germ cell tumours.
European cells & materials 2011;22():258-74; discussio 274.
2011: Thaleia Kouskoura; Lukas Sommer; Maria Alexiou; Natassa Fragou; Daniel Graf; Nessy John; Christos Katsaros; Thimios A Mitsiadis
The genetic basis of craniofacial and dental abnormalities.
Schweizer Monatsschrift für Zahnmedizin = Revue mensuelle suisse d'odonto-stomatologie = Rivista mensile svizzera di odontologia e stomatologia / SSO 2011;121(7-8):636-46.
2011: Eumorphia Remboutsika; Maximilianos Elkouris; Angelo Iulianella; Cynthia L Andoniadou; Maria Poulou; Thimios A Mitsiadis; Paul A Trainor; Robin Lovell-Badge
Flexibility of neural stem cells.
Frontiers in physiology 2011;2():16.
2011: Thimios A Mitsiadis
Everything is on the Head.
Frontiers in physiology 2011;2():2.
2010: Thimios A Mitsiadis; Daniel Graf; Hans-Ulrich Luder; Thomas Gridley; Gilles Bluteau
BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation.
Development (Cambridge, England) 2010;137(18):3025-35.
2009: Thimios A Mitsiadis; Daniel Graf
Cell fate determination during tooth development and regeneration.
Birth defects research. Part C, Embryo today : reviews 2009;87(3):199-211.
2009: Alexandra Karystinou; Francesco Dell'Accio; Tobias B A Kurth; Henning Wackerhage; Ilyas M Khan; Charles W Archer; Elena A Jones; Thimios A Mitsiadis; Cosimo De Bari
Distinct mesenchymal progenitor cell subsets in the adult human synovium.
Rheumatology (Oxford, England) 2009;48(9):1057-64.
2009: Lisa Diep; Eva Matalova; Thimios A Mitsiadis; Abigail S Tucker
Contribution of the tooth bud mesenchyme to alveolar bone.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(5):510-7.
2009: Yael Gruenbaum-Cohen; Abigail S Tucker; Amir Haze; Dekel Shilo; Angela L Taylor; Boaz Shay; Paul T Sharpe; Thimios A Mitsiadis; Asher Ornoy; Anat Blumenfeld; Dan Deutsch
Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(5):445-57.
2009: Thimios A Mitsiadis
Old concepts, current knowledge, new challenges.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(4):247-8.
2009: Moya M Smith; Gareth J Fraser; Thimios A Mitsiadis
Dental lamina as source of odontogenic stem cells: evolutionary origins and developmental control of tooth generation in gnathostomes.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(4):260-80.
2009: Vasiliki Zouvelou; Hans-Ulrich Luder; Thimios A Mitsiadis; Daniel Graf
Deletion of BMP7 affects the development of bones, teeth, and other ectodermal appendages of the orofacial complex.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(4):361-74.
2009: Javier Catón; Hans-Ulrich Luder; Maria Zoupa; Matthew Bradman; Gilles Bluteau; Abigail S Tucker; Ophir Klein; Thimios A Mitsiadis
Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors.
Developmental biology 2009;328(2):493-505.
2008: Thimios A Mitsiadis; Javier Caton; Cosimo De Bari; Gilles Bluteau
The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: the rodent incisor as a model.
Developmental biology 2008;320(1):256-66.
2008: Thimios A Mitsiadis; Abigail S Tucker; Cosimo De Bari; Martyn T Cobourne; David P C Rice
A regulatory relationship between Tbx1 and FGF signaling during tooth morphogenesis and ameloblast lineage determination.
Developmental biology 2008;320(1):39-48.
2008: Thimios A Mitsiadis; Cosimo De Bari; Imad About
Apoptosis in developmental and repair-related human tooth remodeling: a view from the inside.
Experimental cell research 2008;314(4):869-77.
2008: Thimios A Mitsiadis; Jacques Drouin
Deletion of the Pitx1 genomic locus affects mandibular tooth morphogenesis and expression of the Barx1 and Tbx1 genes.
Developmental biology 2008;313(2):887-96.
2008: G Bluteau; H U Luder; Cosimo De Bari; Thimios A Mitsiadis
Stem cells for tooth engineering.
European cells & materials 2008;16():1-9.
2008: Cosimo De Bari; Francesco Dell'Accio; Alexandra Karystinou; Pascale V Guillot; Nicholas M Fisk; Elena A Jones; Dennis McGonagle; Ilyas M Khan; Charles W Archer; Thimios A Mitsiadis; Ana Nora Donaldson; Frank P Luyten; Costantino Pitzalis
A biomarker-based mathematical model to predict bone-forming potency of human synovial and periosteal mesenchymal stem cells.
Arthritis and rheumatism 2008;58(1):240-50.
2007: Thimios A Mitsiadis; Ornella Barrandon; Ariane Rochat; Yann Barrandon; Cosimo De Bari
Stem cell niches in mammals.
Experimental cell research 2007;313(16):3377-85.
2007: Henrik Løvschall; Thimios A Mitsiadis; Knud Poulsen; Kristina H Jensen; Annette L Kjeldsen
Coexpression of Notch3 and Rgs5 in the pericyte-vascular smooth muscle cell axis in response to pulp injury.
The International journal of developmental biology 2007;51(8):715-21.
2006: Thimios A Mitsiadis; Moya M Smith
How do genes make teeth to order through development?
Journal of experimental zoology. Part B, Molecular and developmental evolution 2006;306(3):177-82.
2006: Thimios A Mitsiadis; Javier Caton; Martyn T Cobourne
Waking-up the sleeping beauty: recovery of the ancestral bird odontogenic program.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2006;306(3):227-33.
2006: Martyn T Cobourne; Thimios A Mitsiadis
Neural crest cells and patterning of the mammalian dentition.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2006;306(3):251-60.
2006: Cosimo De Bari; Francesco Dell'Accio; Johan Vanlauwe; Jeroen Eyckmans; Ilyas M Khan; Charles W Archer; Elena A Jones; Dennis McGonagle; Thimios A Mitsiadis; Costantino Pitzalis; Frank P Luyten
Mesenchymal multipotency of adult human periosteal cells demonstrated by single-cell lineage analysis.
Arthritis and rheumatism 2006;54(4):1209-21.
2006: Francesco Dell'Accio; Cosimo De Bari; Noha M F El Tawil; Francesca Barone; Thimios A Mitsiadis; John O'Dowd; Costantino Pitzalis
Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury.
Arthritis research & therapy 2006;8(5):R139.
2006: Maria Zoupa; Maisa Seppala; Thimios A Mitsiadis; Martyn T Cobourne
Tbx1 is expressed at multiple sites of epithelial-mesenchymal interaction during early development of the facial complex.
The International journal of developmental biology 2006;50(5):504-10.
2005: Thimios A Mitsiadis; Laure Regaudiat; Thomas Gridley
Role of the Notch signalling pathway in tooth morphogenesis.
Archives of oral biology 2005;50(2):137-40.
2005: Imad About; Jean Camps; Anne-Sophie Burger; Thimios A Mitsiadis; William T Butler; Jean-Claude Franquin
Polymerized bonding agents and the differentiation in vitro of human pulp cells into odontoblast-like cells.
Dental materials : official publication of the Academy of Dental Materials 2005;21(2):156-63.
2004: Thimios A Mitsiadis; C Rahiotis
Parallels between tooth development and repair: conserved molecular mechanisms following carious and dental injury.
Journal of dental research 2004;83(12):896-902.
2003: Thimios A Mitsiadis; Irene Angeli; Chela T James; Urban Lendahl; Paul T Sharpe
Role of Islet1 in the patterning of murine dentition.
Development (Cambridge, England) 2003;130(18):4451-60.
2003: Sandrine Fraboulet; Katerina Kavvadia; Olivier Pourquié; Paul T Sharpe; Thimios A Mitsiadis
BEN/DM-GRASP/SC1 expression during mouse facial development: differential expression and regulation in molars and incisors.
Gene expression patterns : GEP 2003;3(3):255-9.
2003: Thimios A Mitsiadis; Yvonnick Chéraud; Paul Sharpe; Josiane Fontaine-Pérus
Development of teeth in chick embryos after mouse neural crest transplantations.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6541-5.
2003: Thimios A Mitsiadis; Annick Roméas; Urban Lendahl; Paul T Sharpe; Jean-Christophe Farges
Notch2 protein distribution in human teeth under normal and pathological conditions.
Experimental cell research 2003;282(2):101-9.
2002: Nilima Prakash; Emil M Hansson; Christer Betsholtz; Thimios A Mitsiadis; Urban Lendahl
Mouse Notch 3 expression in the pre- and postnatal brain: relationship to the stroke and dementia syndrome CADASIL.
Experimental cell research 2002;278(1):31-44.
2002: Robert Heymann; Imad About; Urban Lendahl; Jean-Claude Franquin; Björn Obrink; Thimios A Mitsiadis
E- and N-cadherin distribution in developing and functional human teeth under normal and pathological conditions.
The American journal of pathology 2002;160(6):2123-33.
2002: J Camps; Imad About; B Thonneman; Thimios A Mitsiadis; G Schmaltz; Jean-Claude Franquin
Two- versus three-dimensional in vitro differentiation of human pulp cells into odontoblastic cells.
Connective tissue research 2002;43(2-3):396-400.
2002: Imad About; Jean-Pierre Proust; Sylva Raffo; Thimios A Mitsiadis; Jean-Claude Franquin
In vivo and in vitro expression of connexin 43 in human teeth.
Connective tissue research 2002;43(2-3):232-7.
2002: Imad About; Jean Camps; Thimios A Mitsiadis; Marie-José Bottero; William Butler; Jean-Claude Franquin
Influence of resinous monomers on the differentiation in vitro of human pulp cells into odontoblasts.
Journal of biomedical materials research 2002;63(4):418-23.
2001: Thimios A Mitsiadis; Odile Gayet; N Zhang; Patrick Carroll
Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression.
Mechanisms of development 2001;109(2):399-403.
2001: Imad About; Thimios A Mitsiadis
Molecular aspects of tooth pathogenesis and repair: in vivo and in vitro models.
Advances in dental research 2001;15():59-62.
2001: Robert Heymann; S Kallenbach; S Alonso; P Carroll; Thimios A Mitsiadis
Dynamic expression patterns of the new protocadherin families CNRs and Pcdh-gamma during mouse odontogenesis: comparison with reelin expression.
Mechanisms of development 2001;106(1-2):181-4.
2000: Imad About; M J Bottero; P de Denato; Jean Camps; Jean-Claude Franquin; Thimios A Mitsiadis
Human dentin production in vitro.
Experimental cell research 2000;258(1):33-41.
2000: Imad About; D Laurent-Maquin; Urban Lendahl; Thimios A Mitsiadis
Nestin expression in embryonic and adult human teeth under normal and pathological conditions.
The American journal of pathology 2000;157(1):287-95.
2000: Laurent Pouyet; Thimios A Mitsiadis
Dynamic Lunatic fringe expression is correlated with boundaries formation in developing mouse teeth.
Mechanisms of development 2000;91(1-2):399-402.
2000: ML Mucchielli; Thimios A Mitsiadis
Correlation of asymmetric Notch2 expression and mouse incisor rotation.
Mechanisms of development 2000;91(1-2):379-82.
1999: Maria Pia Felli; Marella Maroder; Thimios A Mitsiadis; Antonio F Campese; Diana Bellavia; Alessandra Vacca; R S Mann; Luigi Frati; Urban Lendahl; Alberto Gulino; Isabella Screpanti
Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development.
International immunology 1999;11(7):1017-25.
1999: Thimios A Mitsiadis; K Fried; Christo Goridis
Reactivation of Delta-Notch signaling after injury: complementary expression patterns of ligand and receptor in dental pulp.
Experimental cell research 1999;246(2):312-8.
1998: Thimios A Mitsiadis; E Hirsinger; Urban Lendahl; Christo Goridis
Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.
Developmental biology 1998;204(2):420-31.
1998: Thimios A Mitsiadis; ML Mucchielli; Sylva Raffo; Jean-Pierre Proust; P Koopman; Christo Goridis
Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis.
European journal of oral sciences 1998;106 Suppl 1():112-6.
1997: ML Mucchielli; Thimios A Mitsiadis; Sylva Raffo; Jean-François Brunet; Jean-Pierre Proust; Christo Goridis
Mouse Otlx2/RIEG expression in the odontogenic epithelium precedes tooth initiation and requires mesenchyme-derived signals for its maintenance.
Developmental biology 1997;189(2):275-84.
1997: Thimios A Mitsiadis; Domingos Henrique; I Thesleff; Urban Lendahl
Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4.
Development (Cambridge, England) 1997;124(8):1473-83.
1996: M Lardelli; R Williams; Thimios A Mitsiadis; Urban Lendahl
Expression of the Notch 3 intracellular domain in mouse central nervous system progenitor cells is lethal and leads to disturbed neural tube development.
Mechanisms of development 1996;59(2):177-90.
1996: Thimios A Mitsiadis; J Wroblewski; J L Urdiales; E Becker; D Martin-Zanca; Brian B Rudkin; Urban Lendahl
Expression of Trk receptors during cartilage differentiation.
Annals of the New York Academy of Sciences 1996;785():298-300.
1996: Thimios A Mitsiadis; Irma Thesleff; Urban Lendahl
Mouse Serrate-1 and Notch genes differ in their response to signaling molecules during odontogenesis.
The International journal of developmental biology 1996;Suppl 1():113S-114S.
1995: C Terling; A Rass; Thimios A Mitsiadis; K Fried; Urban Lendahl; J Wroblewski
Expression of the intermediate filament nestin during rodent tooth development.
The International journal of developmental biology 1995;39(6):947-56.
1995: Thimios A Mitsiadis; M Lardelli; Urban Lendahl; Irma Thesleff
Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate.
The Journal of cell biology 1995;130(2):407-18.
1995: Thimios A Mitsiadis; T Muramatsu; H Muramatsu; Irma Thesleff
Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis.
The Journal of cell biology 1995;129(1):267-81.
1995: Thimios A Mitsiadis; K Luukko
Neurotrophins in odontogenesis.
The International journal of developmental biology 1995;39(1):195-202.
1995: Thimios A Mitsiadis; M Salmivirta; T Muramatsu; H Muramatsu; Heikki Rauvala; Eero Lehtonen; Markku Jalkanen; Irma Thesleff
Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis.
Development (Cambridge, England) 1995;121(1):37-51.
1993: Thimios A Mitsiadis; Pierre Couble; E Dicou; Brian B Rudkin; H Magloire
Patterns of nerve growth factor (NGF), proNGF, and p75 NGF receptor expression in the rat incisor: comparison with expression in the molar.
Differentiation; research in biological diversity 1993;54(3):161-75.
1992: Thimios A Mitsiadis; E Dicou; A Joffre; H Magloire
Immunohistochemical localization of nerve growth factor (NGF) and NGF receptor (NGF-R) in the developing first molar tooth of the rat.
Differentiation; research in biological diversity 1992;49(1):47-61.
1990: Thimios A Mitsiadis; H Magloire
[Epidermal growth factor in tooth development].
Actualités odonto-stomatologiques 1990;44(170):257-70.