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Kunitoshi Mitsumori

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Co-Publications
Name
57
Onodera, Hiroshi
57
Yasuhara, Kazuo
41
Takahashi, Mika
41
Hirose, Masao
25
Kashida, Yoko
23
Hayashi, Y
22
Jin, Meilan
20
Imazawa, Takayoshi
20
Nishimura, Jihei
19
Moto, Mitsuyoshi
19
Muguruma, Masako
18
Shimo, T
18
Dewa, Yasuaki
18
Takegawa, Kiyoshi
17
Tamura, Toru

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Publications

TOP 3
Saegusa Yukie; Fujimoto Hitoshi; Woo Gye-Hyeong; Inoue Kaoru; Takahashi Miwa; Mitsumori Kunitoshi; Hirose Masao; Nishikawa Akiyoshi; Shibutani Makoto
Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation.
Jin Meilan; Dewa Yasuaki; Kawai Masaomi; Nishimura Jihei; Saegusa Yukie; Kemmochi Sayaka; Harada Tomoaki; Shibutani Makoto; Mitsumori Kunitoshi
Induction of liver preneoplastic foci in F344 rats subjected to 28-day oral administration of diheptyl phthalate and its in vivo genotoxic potential.
Shima Tomomi; Nishimura Jihei; Dewa Yasuaki; Saegusa Yukie; Matsumoto Sayaka; Kawai Masaomi; Harada Tomoaki; Mitsumori Kunitoshi; Shibutani Makoto
Modification of dietary copper levels on the early stage of tumor-promotion with propylthiouracil in a rat two-stage thyroid carcinogenesis model.

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All Publications

2009: Saegusa Yukie; Fujimoto Hitoshi; Woo Gye-Hyeong; Inoue Kaoru; Takahashi Miwa; Mitsumori Kunitoshi; Hirose Masao; Nishikawa Akiyoshi; Shibutani Makoto
Developmental toxicity of brominated flame retardants, tetrabromobisphenol A and 1,2,5,6,9,10-hexabromocyclododecane, in rat offspring after maternal exposure from mid-gestation through lactation.
Reproductive toxicology (Elmsford, N.Y.) 2009;28(4):456-67.
2009: Jin Meilan; Dewa Yasuaki; Kawai Masaomi; Nishimura Jihei; Saegusa Yukie; Kemmochi Sayaka; Harada Tomoaki; Shibutani Makoto; Mitsumori Kunitoshi
Induction of liver preneoplastic foci in F344 rats subjected to 28-day oral administration of diheptyl phthalate and its in vivo genotoxic potential.
Toxicology 2009;264(1-2):16-25.
2009: Shima Tomomi; Nishimura Jihei; Dewa Yasuaki; Saegusa Yukie; Matsumoto Sayaka; Kawai Masaomi; Harada Tomoaki; Mitsumori Kunitoshi; Shibutani Makoto
Modification of dietary copper levels on the early stage of tumor-promotion with propylthiouracil in a rat two-stage thyroid carcinogenesis model.
Chemico-biological interactions 2009;180(2):262-70.
2009: Taniai Eriko; Kawai Masaomi; Dewa Yasuaki; Nishimura Jihei; Harada Tomoaki; Saegusa Yukie; Matsumoto Sayaka; Takahashi Miwa; Mitsumori Kunitoshi; Shibutani Makoto
Crosstalk between PTEN/Akt2 and TGFbeta signaling involving EGF receptor down-regulation during the tumor promotion process from the early stage in a rat two-stage hepatocarcinogenesis model.
Cancer science 2009;100(5):813-20.
2009: Dewa Yasuaki; Nishimura Jihei; Muguruma Masako; Jin Meilan; Kawai Masaomi; Saegusa Yukie; Okamura Toshiya; Umemura Takashi; Mitsumori Kunitoshi
Involvement of oxidative stress in hepatocellular tumor-promoting activity of oxfendazole in rats.
Archives of toxicology 2009;83(5):503-11.
2009: Ago Kyohei; Shibutani Makoto; Saegusa Yukie; Shima Tomomi; Taniai Eriko; Mitsumori Kunitoshi
A case report of a cerebellar neuroblastoma in a p53 null mutation mouse.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2009;71(3):345-7.
2009: Matsumoto Sayaka; Jin Meilan; Dewa Yasuaki; Nishimura Jihei; Moto Mitsuyoshi; Murata Yuji; Shibutani Makoto; Mitsumori Kunitoshi
Suppressive effect of Siraitia grosvenorii extract on dicyclanil-promoted hepatocellular proliferative lesions in male mice.
The Journal of toxicological sciences 2009;34(1):109-18.
2009: Muguruma Masako; Kawai Masaomi; Dewa Yasuaki; Nishimura Jihei; Saegusa Yukie; Yasuno Hironobu; Jin Meilan; Matsumoto Sayaka; Takabatake Masayoshi; Arai Katsuhiko; Mitsumori Kunitoshi
Threshold dose of piperonyl butoxide that induces reactive oxygen species-mediated hepatocarcinogenesis in rats.
Archives of toxicology 2009;83(2):183-93.
2009: Jin Meilan; Saekusa Yukie; Dewa Yasuaki; Nishimura Jihei; Matsumoto Sayaka; Shibutani Makoto; Hasumi Keiji; Mitsumori Kunitoshi
Hepatocarcinogenic susceptibility of rasH2 mice to troglitazone in a two-stage hepatocarcinogenesis model.
Archives of toxicology 2009;83(2):173-81.
2009: Kawai Masaomi; Saegusa Yukie; Jin Meilan; Dewa Yasuaki; Nishimura Jihei; Harada Tomoaki; Shibutani Makoto; Mitsumori Kunitoshi
Mechanistic study on hepatocarcinogenesis of piperonyl butoxide in mice.
Toxicologic pathology 2009;37(6):761-9.
2009: Dewa Yasuaki; Nishimura Jihei; Jin Meilan; Kawai Masaomi; Saegusa Yukie; Harada Tomoaki; Shibutani Makoto; Mitsumori Kunitoshi
Molecular expression analysis of beta-naphthoflavone-induced hepatocellular tumors in rats.
Toxicologic pathology 2009;37(4):446-55.
2008: Nishimura Jihei; Dewa Yasuaki; Okamura Toshiya; Jin Meilan; Saegusa Yukie; Kawai Masaomi; Umemura Takashi; Shibutani Makoto; Mitsumori Kunitoshi
Role of Nrf2 and oxidative stress on fenofibrate-induced hepatocarcinogenesis in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2008;106(2):339-49.
2008: Jin Meilan; Matsumoto Sayaka; Dewa Yasuaki; Nishimura Jihei; Saekusa Yukie; Hasumi Keiji; Mitsumori Kunitoshi
Extremely weak tumor-promoting effect of troglitazone on splenic hemangiosarcomas in rasH2 mice induced by urethane.
Archives of toxicology 2008;82(10):771-7.
2008: Muguruma Masako; Arai Katsuhiko; Moto Mitsuyoshi; Nishimura Jihei; Dewa Yasuaki; Mitsumori Kunitoshi
Piperonyl butoxide activates c-Jun and ATF-2 in the hepatocytes of mice.
Archives of toxicology 2008;82(10):749-53.
2008: Nishimura Jihei; Dewa Yasuaki; Okamura Toshiya; Muguruma Masako; Jin Meilan; Saegusa Yukie; Umemura Takashi; Mitsumori Kunitoshi
Possible involvement of oxidative stress in fenofibrate-induced hepatocarcinogenesis in rats.
Archives of toxicology 2008;82(9):641-54.
2008: Kuroiwa Yuichi; Yamada Masami; Matsui Keiko; Okamura Toshiya; Ishii Yuji; Masumura Ken-ichi; Tasaki Masako; Umemura Takashi; Mitsumori Kunitoshi; Nohmi Takehiko; Hirose Masao; Nishikawa Akiyoshi
Combined ascorbic acid and sodium nitrite treatment induces oxidative DNA damage-associated mutagenicity in vitro, but lacks initiation activity in rat forestomach epithelium.
Toxicological sciences : an official journal of the Society of Toxicology 2008;104(2):274-82.
2008: Takabatake Masayoshi; Shibutani Makoto; Dewa Yasuaki; Nishimura Jihei; Yasuno Hironobu; Jin Meilan; Muguruma Masako; Kono Taichi; Mitsumori Kunitoshi
Concurrent administration of ascorbic acid enhances liver tumor-promoting activity of kojic acid in rats.
The Journal of toxicological sciences 2008;33(2):127-40.
2008: Takabatake Masayoshi; Takuwa Yoh; Takuwa Noriko; Yasuno Hironobu; Matsumoto Sayaka; Shibutani Makoto; Mitsumori Kunitoshi
A case report of a renal mixed epithelial and stromal tumor in a heterozygous S1P2 receptor deficient mouse.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2008;70(5):483-5.
2008: Dewa Yasuaki; Nishimura Jihei; Muguruma Masako; Jin Meilan; Saegusa Yukie; Okamura Toshiya; Tasaki Masako; Umemura Takashi; Mitsumori Kunitoshi
beta-Naphthoflavone enhances oxidative stress responses and the induction of preneoplastic lesions in a diethylnitrosamine-initiated hepatocarcinogenesis model in partially hepatectomized rats.
Toxicology 2008;244(2-3):179-89.
2008: Kuroiwa Yuichi; Okamura Toshiya; Ishii Yuji; Umemura Takashi; Tasaki Masako; Kanki Keita; Mitsumori Kunitoshi; Hirose Masao; Nishikawa Akiyoshi
Enhancement of esophageal carcinogenesis in acid reflux model rats treated with ascorbic acid and sodium nitrite in combination with or without initiation.
Cancer science 2008;99(1):7-13.
2008: Kawai Masaomi; Jin Meilan; Nishimura Jihei; Dewa Yasuaki; Saegusa Yukie; Matsumoto Sayaka; Taniai Eriko; Shibutani Makoto; Mitsumori Kunitoshi
Hepatocarcinogenic susceptibility of fenofibrate and its possible mechanism of carcinogenicity in a two-stage hepatocarcinogenesis model of rasH2 mice.
Toxicologic pathology 2008;36(7):950-7.
2007: Jin Meilan; Takahashi Miwa; Moto Mitsuyoshi; Muguruma Masako; Ito Kazumi; Watanabe Kyoko; Kenmochi Yusuke; Kono Taichi; Hasumi Keiji; Mitsumori Kunitoshi
Carcinogenic susceptibility of rasH2 mice to troglitazone.
Archives of toxicology 2007;81(12):883-94.
2007: Kono Taichi; Moto Mitsuyoshi; Muguruma Masako; Takahashi Miwa; Jin Meilan; Kenmochi Yusuke; Yokouchi Yusuke; Mitsumori Kunitoshi
Enhancement of hepatocellular proliferative activity of kojic acid in mice by a simultaneous administration of ascorbic acid.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2007;69(9):899-908.
2007: Umemura Takashi; Kuroiwa Yuichi; Tasaki Masako; Okamura Toshiya; Ishii Yuji; Kodama Yukio; Nohmi Takehiko; Mitsumori Kunitoshi; Nishikawa Akiyoshi; Hirose Masao
Detection of oxidative DNA damage, cell proliferation and in vivo mutagenicity induced by dicyclanil, a non-genotoxic carcinogen, using gpt delta mice.
Mutation research 2007;633(1):46-54.
2007: Dewa Yasuaki; Nishimura Jihei; Muguruma Masako; Matsumoto Sayaka; Takahashi Miwa; Jin Meilan; Mitsumori Kunitoshi
Gene expression analyses of the liver in rats treated with oxfendazole.
Archives of toxicology 2007;81(9):647-54.
2007: Muguruma Masako; Unami Akira; Kanki Masayuki; Kuroiwa Yuichi; Nishimura Jihei; Dewa Yasuaki; Umemura Takashi; Oishi Yuji; Mitsumori Kunitoshi
Possible involvement of oxidative stress in piperonyl butoxide induced hepatocarcinogenesis in rats.
Toxicology 2007;236(1-2):61-75.
2007: Kuroiwa Yuichi; Ishii Yuji; Umemura Takashi; Kanki Keita; Mitsumori Kunitoshi; Nishikawa Akiyoshi; Nakazawa Hiroyuki; Hirose Masao
Combined treatment with green tea catechins and sodium nitrite selectively promotes rat forestomach carcinogenesis after initiation with N-methyl-N'- nitro-N-nitrosoguanidine.
Cancer science 2007;98(7):949-57.
2007: Jin Meilan; Muguruma Masako; Moto Mitsuyoshi; Okamura Miwa; Kashida Yoko; Mitsumori Kunitoshi
Thirteen-week repeated dose toxicity of Siraitia grosvenori extract in Wistar Hannover (GALAS) rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2007;45(7):1231-7.
2007: Nishimura Jihei; Dewa Yasuaki; Muguruma Masako; Kuroiwa Yuichi; Yasuno Hiroaki; Shima Tomomi; Jin Mailan; Takahashi Miwa; Umemura Takashi; Mitsumori Kunitoshi
Effect of fenofibrate on oxidative DNA damage and on gene expression related to cell proliferation and apoptosis in rats.
Toxicological sciences : an official journal of the Society of Toxicology 2007;97(1):44-54.
2007: Itoh Tadashi; Moto Mitsuyoshi; Kuroiwa Yuichi; Sakai Hiroki; Mitsumori Kunitoshi
The initiation activity of norfloxacin does not result in the induction of hepatocellular tumors in rats.
Toxicology 2007;231(2-3):234-42.
2007: Okamura Miwa; Unami Akira; Moto Mitsuyoshi; Muguruma Masako; Ito Tadashi; Jin Meilan; Oishi Yuji; Kashida Yoko; Mitsumori Kunitoshi
The possible mechanism of enhanced carcinogenesis induced by genotoxic carcinogens in rasH2 mice.
Cancer letters 2007;245(1-2):321-30.
2006: Muguruma Masako; Nishimura Jihei; Jin Meilan; Kashida Yoko; Moto Mitsuyoshi; Takahashi Miwa; Yokouchi Yusuke; Mitsumori Kunitoshi
Molecular pathological analysis for determining the possible mechanism of piperonyl butoxide-induced hepatocarcinogenesis in mice.
Toxicology 2006;228(2-3):178-87.
2006: Moto Mitsuyoshi; Umemura Takashi; Okamura Miwa; Muguruma Masako; Ito Tadashi; Jin Mailan; Kashida Yoko; Mitsumori Kunitoshi
Possible involvement of oxidative stress in dicyclanil-induced hepatocarcinogenesis in mice.
Archives of toxicology 2006;80(10):694-702.
2006: Kashida Yoko; Takahashi Akiko; Moto Mitsuyoshi; Okamura Miwa; Muguruma Masako; Jin Meilan; Arai Katsuhiko; Mitsumori Kunitoshi
Gene expression analysis in mice liver on hepatocarcinogenesis by flumequine.
Archives of toxicology 2006;80(8):533-9.
2006: Tamura Toru; Mitsumori Kunitoshi; Totsuka Yukari; Wakabayashi Keiji; Kido Rie; Kasai Hiroshi; Nasu Masahiro; Hirose Masao
Absence of in vivo genotoxic potential and tumor initiation activity of kojic acid in the rat thyroid.
Toxicology 2006;222(3):213-24.
2006: Itoh Tadashi; Moto Mitsuyoshi; Takahashi Miwa; Sakai Hiroki; Mitsumori Kunitoshi
Liver initiation activity of norfloxacin but not nalidixic acid, pipemidic acid, and ciprofloxacin on in vivo short-term liver initiation assay in rats.
Toxicology 2006;222(3):240-6.
2006: Moto Mitsuyoshi; Mori Taeko; Okamura Miwa; Kashida Yoko; Mitsumori Kunitoshi
Absence of liver tumor-initiating activity of kojic acid in mice.
Archives of toxicology 2006;80(5):299-304.
2006: Itoh Tadashi; Mitsumori Kunitoshi; Kawaguchi Satomi; Sasaki Yu F
Genotoxic potential of quinolone antimicrobials in the in vitro comet assay and micronucleus test.
Mutation research 2006;603(2):135-44.
2006: Okamura Miwa; Unami Akira; Matsumoto Masahiro; Oishi Yuji; Kashida Yoko; Mitsumori Kunitoshi
Gene expression analysis of urethane-induced lung tumors in ras H2 mice.
Toxicology 2006;217(2-3):129-38.
2006: Ota Y; Hasumura M; Okamura M; Takahashi A; Ueda M; Onodera H; Imai T; Mitsumori K; Hirose M
Chronic toxicity and carcinogenicity of dietary administered ammonium sulfate in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2006;44(1):17-27.
2006: Moto Mitsuyoshi; Okamura Miwa; Muguruma Masako; Ito Tadasi; Jin Meilan; Kashida Yoko; Mitsumori Kunitoshi
Gene expression analysis on the dicyclanil-induced hepatocellular tumors in mice.
Toxicologic pathology 2006;34(6):744-51.
2006: Okamura Miwa; Moto Mitsuyoshi; Muguruma Masako; Ito Tadashi; Jin Meilan; Kashida Yoko; Mitsumori Kunitoshi
A 26-week carcinogenicity study of 2-amino-3-methylimidazo[4,5-f]quinoline in rasH2 mice.
Toxicologic pathology 2006;34(2):199-205.
2005: Muguruma Masako; Yamazaki Masaki; Okamura Miwa; Moto Mitsuyoshi; Kashida Yoko; Mitsumori Kunitoshi
Molecular mechanism on the testicular toxicity of 1,3-dinitrobenzene in Sprague-Dawley rats: preliminary study.
Archives of toxicology 2005;79(12):729-36.
2005: Takagi Hironori; Shibutani Makoto; Lee Kyoung-Youl; Masutomi Naoya; Fujita Haruka; Inoue Kaoru; Mitsumori Kunitoshi; Hirose Masao
Impact of maternal dietary exposure to endocrine-acting chemicals on progesterone receptor expression in microdissected hypothalamic medial preoptic areas of rat offspring.
Toxicology and applied pharmacology 2005;208(2):127-36.
2005: Machida N; Katsuda S; Kobayashi Y; Mitsumori K
A histological study of the cardiac conduction system in a heifer with complete atrioventricular block.
Journal of comparative pathology 2005;133(1):68-72.
2005: Kobayashi M; Kashida Y; Yoneda K; Iwata H; Watanabe M; Tanabe S; Fukatsu H; Machida N; Mitsumori K
Thyroid lesions and dioxin accumulation in the livers of jungle crows (Corvus macrorhynchos) in urban and suburban Tokyo.
Archives of environmental contamination and toxicology 2005;48(3):424-32.
2005: Hayashi Morimichi; Tamura Toru; Kuroda Junji; Ohnota Hideki; Shibata Nobuo; Akahane Masuo; Kashida Yoko; Mitsumori Kunitoshi
Different inhibitory effects in the early and late phase of treatment with KAT-681, a liver-selective thyromimetic, on rat hepatocarcinogenesis induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
Toxicological sciences : an official journal of the Society of Toxicology 2005;84(1):22-8.
2005: Ueda Makoto; Imai Toshio; Takizawa Tamotsu; Onodera Hiroshi; Mitsumori Kunitoshi; Matsui Takane; Hirose Masao
Possible enhancing effects of atrazine on growth of 7,12-dimethylbenz(a) anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Cancer science 2005;96(1):19-25.
2004: Okamura Miwa; Sumida Kayo; Muto Tomoko; Kashida Yoko; Machida Noboru; Watanabe Tomoyuki; Mitsumori Kunitoshi
Analysis of gene expression profiles of forestomach tumors in rasH2 mice initiated with N-ethyl-N-nitrosourea.
Archives of toxicology 2004;78(12):688-96.
2004: Takizawa Tamotsu; Imai Toshio; Onose Jun-ichi; Ueda Makoto; Tamura Toru; Mitsumori Kunitoshi; Izumi Keisuke; Hirose Masao
Enhancement of hepatocarcinogenesis by kojic acid in rat two-stage models after initiation with N-bis(2-hydroxypropyl)nitrosamine or N-diethylnitrosamine.
Toxicological sciences : an official journal of the Society of Toxicology 2004;81(1):43-9.
2004: Machida N; Tanaka R; Takemura N; Fujii Y; Ueno A; Mitsumori K
Development of pericardial mesothelioma in golden retrievers with a long-term history of idiopathic haemorrhagic pericardial effusion.
Journal of comparative pathology 2004;131(2-3):166-75.
2004: Hayashi Morimichi; Ohnota Hideki; Tamura Toru; Kuroda Junji; Shibata Nobuo; Akahane Masuo; Moriwaki Hisataka; Machida Noboru; Mitsumori Kunitoshi
Inhibitory effects of KAT-681, a liver-selective thyromimetic, on development of hepatocellular proliferative lesions in rats induced by 2-acetylaminofluorene and partial hepatectomy after diethylnitrosamine initiation.
Archives of toxicology 2004;78(8):460-6.
2004: Okamura Miwa; Moto Mitsuyoshi; Kashida Yoko; Machida Noboru; Mitsumori Kunitoshi
Carcinogenic susceptibility to N-bis(2-hydroxypropyl)nitrosamine (DHPN) in rasH2 mice.
Toxicologic pathology 2004;32(4):474-81.
2004: Takagi Hironori; Shibutani Makoto; Lee Kyoung-Youl; Lee Hwi Cheul; Nishihara Masugi; Uneyama Chikako; Takigami Shu; Mitsumori Kunitoshi; Hirose Masao
Lack of modifying effects of genistein on disruption of the reproductive system by perinatal dietary exposure to ethinylestradiol in rats.
Reproductive toxicology (Elmsford, N.Y.) 2004;18(5):687-700.
2004: Takagi Hironori; Shibutani Makoto; Kato Natsumi; Fujita Haruka; Lee Kyoung-Youl; Takigami Shu; Mitsumori Kunitoshi; Hirose Masao
Microdissected region-specific gene expression analysis with methacarn-fixed, paraffin-embedded tissues by real-time RT-PCR.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2004;52(7):903-13.
2004: Hasumura M; Yasuhara K; Tamura T; Imai T; Mitsumori K; Hirose M
Evaluation of the toxicity of enzymatically decomposed rutin with 13-weeks dietary administration to Wistar rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(3):439-44.
2004: Moto Mitsuyoshi; Okamura Miwa; Watanabe Takao; Kashida Yoko; Mitsumori Kunitoshi
Thirteen-week repeated dose toxicity of rice bran glycosphingolipid in Wistar Hannover (GALAS) rats.
The Journal of toxicological sciences 2004;29(1):73-80.
2004: Takagi Hironori; Shibutani Makoto; Masutomi Naoya; Uneyama Chikako; Takahashi Noriyuki; Mitsumori Kunitoshi; Hirose Masao
Lack of maternal dietary exposure effects of bisphenol A and nonylphenol during the critical period for brain sexual differentiation on the reproductive/endocrine systems in later life.
Archives of toxicology 2004;78(2):97-105.
2004: Okamura Miwa; Watanabe Takao; Kashida Yoko; Machida Noboru; Mitsumori Kunitoshi
Possible mechanisms underlying the testicular toxicity of oxfendazole in rats.
Toxicologic pathology 2004;32(1):1-8.
2004: Takizawa T; Mitsumori K; Takagi H; Nasu M; Yasuhara K; Onodera H; Imai T; Hirose M
Sequential analysis of testicular lesions and serum hormone levels in rats treated with a Psoralea corylifolia extract.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2004;42(1):1-7.
2003: Muto Tomoko; Watanabe Takao; Okamura Miwa; Moto Mitsuyoshi; Kashida Yoko; Mitsumori Kunitoshi
Thirteen-week repeated dose toxicity study of wormwood (Artemisia absinthium) extract in rats.
The Journal of toxicological sciences 2003;28(5):471-8.
2003: Mitsumori Kunitoshi
Possible mechanism on enhanced carcinogenesis of genotoxic carcinogens and unsolved mechanisms on lesser carcinogenic susceptibility to some carcinogens in rasH2 mice.
The Journal of toxicological sciences 2003;28(5):371-83.
2003: Watanabe Takao; Kashida Yoko; Ueda Makoto; Onodera Hiroshi; Takizawa Tamotsu; Hirose Masao; Mitsumori Kunitoshi
Inhibition by ethinylestradiol of N-ethyl-N-nitrosourea-initiated uterine carcinogenesis in transgenic mice carrying a human prototype C-Ha-ras gene (rasH2 mice).
Toxicologic pathology 2003;31(5):496-505.
2003: Toyosawa Kaoru; Tanaka Kohji; Imai Toshio; Yasuhara Kazuo; Koujitani Takatoshi; Hirose Masao; Mitsumori Kunitoshi
Mutation and overexpression of the transgene in ethylnitrosourea-induced tumors in mice carrying a human prototype c-Ha-ras gene.
Toxicologic pathology 2003;31(5):491-5.
2003: Kashida Yoko; Ishikawa Kazumi; Arai Katsuhiko; Mitsumori Kunitoshi
Morphological characterization of skin ganglion-like cells in Djungarian hamsters (Phodopus sungorus).
Veterinary pathology 2003;40(5):548-55.
2003: Moto Mitsuyoshi; Sasaki Yu F; Okamura Miwa; Fujita Miho; Kashida Yoko; Machida Noboru; Mitsumori Kunitoshi
Absence of in vivo genotoxicity and liver initiation activity of dicyclanil.
The Journal of toxicological sciences 2003;28(3):173-9.
2003: Okamura Miwa; Yasuhara Kazuo; Koujitani Takatoshi; Nasu Masahiro; Hirose Masao; Mitsumori Kunitoshi
Dose-threshold for thyroid tumor-promoting effects of xylazine in rats.
Toxicology 2003;188(2-3):275-83.
2003: Takizawa Tamotsu; Mitsumori Kunitoshi; Tamura Toru; Nasu Masahiro; Ueda Makoto; Imai Toshio; Hirose Masao
Hepatocellular tumor induction in heterozygous p53-deficient CBA mice by a 26-week dietary administration of kojic acid.
Toxicological sciences : an official journal of the Society of Toxicology 2003;73(2):287-93.
2003: Tomisawa Masashi; Suemizu Hiroshi; Ohnishi Yasuyuki; Maruyama Chika; Urano Kohji; Usui Toshimi; Yasuhara Kazuo; Tamaoki Norikazu; Mitsumori Kunitoshi
Mutation analysis of vinyl carbamate or urethane induced lung tumors in rasH2 transgenic mice.
Toxicology letters 2003;142(1-2):111-7.
2003: Okamura Miwa; Kashida Yoko; Watanabe Takao; Yasuhara Kazuo; Onodera Hiroshi; Hirose Masao; Usui Toshimi; Tamaoki Norikazu; Mitsumori Kunitoshi
Lack of susceptibility of heterozygous p53-knockout CBA and CIEA mice to phenolphthalein in a 6-month carcinogenicity study.
Toxicology 2003;185(1-2):17-22.
2003: Machida N; Kobayashi M; Tanaka R; Katsuda S; Mitsumori K
Primary malignant mixed mesenchymal tumour of the heart in a dog.
Journal of comparative pathology 2003;128(1):71-4.
2003: Ueda Makoto; Niho Naoko; Imai Toshio; Shibutani Makoto; Mitsumori Kunitoshi; Matsui Takane; Hirose Masao
Lack of significant effects of genistein on the progression of 7,12-dimethylbenz(a)anthracene-induced mammary tumors in ovariectomized Sprague-Dawley rats.
Nutrition and cancer 2003;47(2):141-7.
2002: Mitsumori Kunitoshi
Evaluation on carcinogenicity of chemicals using transgenic mice.
Toxicology 2002;181-182():241-4.
2002: Watanabe Takao; Kashida Yoko; Yasuhara Kazuo; Koujitani Takatoshi; Hirose Masao; Mitsumori Kunitoshi
Rapid induction of uterine endometrial proliferative lesions in transgenic mice carrying a human prototype c-Ha-ras gene (rasH2 mice) given a single intraperitoneal injection of N-ethyl-N-nitrosourea.
Cancer letters 2002;188(1-2):39-46.
2002: Machida N; Katsuda S; Yamamura H; Kashida Y; Mitsumori K
Myocardial hamartoma of the right atrium in a dog.
Journal of comparative pathology 2002;127(4):297-300.
2002: Imai T; Yasuhara K; Matsui H; Maruyama S; Fujimoto N; Mitsumori K; Hirose M
Iron lactate induction of pancreatic and endometrial proliferative lesions and a lack of increased tumors in a 104-week carcinogenicity study in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2002;40(10):1441-8.
2002: Kashida Yoko; Sasaki Yu F; Ohsawa Koh-ichi; Yokohama Natsue; Takahashi Akiko; Watanabe Takao; Mitsumori Kunitoshi
Mechanistic study on flumequine hepatocarcinogenicity focusing on DNA damage in mice.
Toxicological sciences : an official journal of the Society of Toxicology 2002;69(2):317-21.
2002: Uehara Takeki; Kashida Yoko; Watanabe Takao; Yasuhara Kazuo; Onodera Hiroshi; Hirose Masao; Mitsumori Kunitoshi
Susceptibility of liver proliferative lesions in heterozygous p53 deficient CBA mice to various carcinogens.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2002;64(7):551-6.
2002: Ueda Makoto; Takagi Hisayoshi; Onodera Hiroshi; Yasuhara Kazuo; Takizawa Tamotsu; Imai Toshio; Mitsumori Kunitoshi; Matsui Takane; Hirose Masao
Enhancing effects of beta-estradiol 3-benzoate but not methoxychlor on the promotion/progression stage of chemically-induced mammary carcinogenesis in ovariectomized rats.
Japanese journal of cancer research : Gann 2002;93(7):752-9.
2002: Imaoka Masako; Kashida Yoko; Watanabe Takao; Ueda Makoto; Onodera Hiroshi; Hirose Masao; Mitsumori Kunitoshi
Tumor promoting effect of phenolphthalein on development of lung tumors induced by N-ethyl-N-nitrosourea in transgenic mice carrying human prototype c-Ha-ras gene.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2002;64(6):489-93.
2002: Takizawa Tamotsu; Imai Toshio; Mitsumori Kunitoshi; Takagi Hisayoshi; Onodera Hiroshi; Yasuhara Kazuo; Ueda Makoto; Tamura Toru; Hirose Masao
Gonadal toxicity of an ethanol extract of Psoralea corylifolia in a rat 90-day repeated dose study.
The Journal of toxicological sciences 2002;27(2):97-105.
2002: Takagi Hisayoshi; Mitsumori Kunitoshi; Onodera Hiroshi; Nasu Masahiro; Tamura Toru; Yasuhara Kazuo; Takegawa Kiyoshi; Hirose Masao
Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats.
Cancer letters 2002;178(1):1-9.
2002: Imai Toshio; Yasuhara Kazuo; Tamura Toru; Takizawa Tamotsu; Ueda Makoto; Hirose Masao; Mitsumori Kunitoshi
Inhibitory effects of cinnamaldehyde on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung carcinogenesis in rasH2 mice.
Cancer letters 2002;175(1):9-16.
2001: Shibutani M; Mitsumori K; Satoh S; Hiratsuka H; Satoh M; Sumiyoshi M; Nishijima M; Katsuki Y; Suzuki J; Nakagawa J; Akagi T; Imazawa T; Ando M
Relationship between toxicity and cadmium accumulation in rats given low amounts of cadmium chloride or cadmium-polluted rice for 22 months.
The Journal of toxicological sciences 2001;26(5):337-58.
2001: Koujitani T; Yasuhara K; Tamura T; Onodera H; Takagi H; Takizawa T; Hirose M; Hayashi Y; Mitsumori K
Lack of modifying effects of eugenol on development of lung proliferative lesions induced by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
The Journal of toxicological sciences 2001;26(3):129-39.
2001: Shoda T; Yasuhara K; Moriyasu M; Takahashi T; Uneyama C; Hirose M; Mitsumori K
Testicular toxicity of nitrofurazone causing germ cell apoptosis in rats.
Archives of toxicology 2001;75(5):297-305.
2001: Koujitani T; Yasuhara K; Toyosawa K; Shimada A; Onodera H; Takagi H; Tamura T; Hirose M; Mitsumori K
Immunohistochemical and ultrastructural studies of 2,6-dimethylaniline-induced nasal proliferative lesions in a rat two-stage nasal carcinogenesis model initiated with N-bis(2-hydroxypropyl)nitrosamine.
Toxicologic pathology 2001;29(3):300-7.
2001: Tamura T; Mitsumori K; Onodera H; Fujimoto N; Yasuhara K; Takegawa K; Takagi H; Hirose M
Dose-threshold for thyroid tumor-promoting effects of orally administered kojic acid in rats after initiation with N-bis(2-hydroxypropyl) nitrosamine.
The Journal of toxicological sciences 2001;26(2):85-94.
2001: Yasuhara K; Koujitani T; Takegawa K; Nasu M; Onodera H; Takagi H; Hirose M; Mitsumori K
Promoting effects of xylazine on development of thyroid tumors in rats initiated with N-bis(2-hydroxypropyl)nitrosamine and the mechanism of action.
Carcinogenesis 2001;22(4):613-8.
2001: Maruyama C; Tomisawa M; Wakana S; Yamazaki H; Kijima H; Suemizu H; Ohnishi Y; Urano K; Hioki K; Usui T; Nakamura M; Tsuchida T; Mitsumori K; Nomura T; Tamaoki N; Ueyama Y
Overexpression of human H-ras transgene is responsible for tumors induced by chemical carcinogens in mice.
Oncology reports 2001;8(2):233-7.
2000: Shibutani M; Mitsumori K; Niho N; Satoh S; Hiratsuka H; Satoh M; Sumiyoshi M; Nishijima M; Katsuki Y; Suzuki J; Nakagawa J; Ando M
Assessment of renal toxicity by analysis of regeneration of tubular epithelium in rats given low-dose cadmium chloride or cadmium-polluted rice for 22 months.
Archives of toxicology 2000;74(10):571-7.
2000: Mitsumori K; Shimo T; Onodera H; Takagi H; Yasuhara K; Tamura T; Aoki Y; Nagata O; Hirose M
Modifying effects of ethinylestradiol but not methoxychlor on N-ethyl-N-nitrosourea-induced uterine carcinogenesis in heterozygous p53-deficient CBA mice.
Toxicological sciences : an official journal of the Society of Toxicology 2000;58(1):43-9.
2000: Takegawa K; Mitsumori K; Yasuhara K; Moriyasu M; Sakamori M; Onodera H; Hirose M; Nomura T
A mechanistic study of ovarian carcinogenesis induced by nitrofurazone using rasH2 mice.
Toxicologic pathology 2000;28(5):649-55.
2000: Takegawa K; Mitsumori K; Onodera H; Shimo T; Kitaura K; Yasuhara K; Hirose M; Takahashi M
Studies on the carcinogenicity of potassium iodide in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2000;38(9):773-81.
2000: Koujitani T; Yasuhara K; Ikeda T; Imazawa T; Tamura T; Toyosawa K; Shimada A; Hirose M; Mitsumori K
Sequential observation of 2,6-dimethylaniline-induced nasal lesions in a rat two-stage nasal carcinogenesis model after initiation with N-bis(2-hydroxypropyl) nitrosamine.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 2000;62(7):751-6.
2000: Shoda T; Mitsumori K; Onodera H; Toyoda K; Uneyama C; Takada K; Hirose M
Liver tumor-promoting effect of beta-naphthoflavone, a strong CYP 1A1/2 inducer, and the relationship between CYP 1A1/2 induction and Cx32 decrease in its hepatocarcinogenesis in the rat.
Toxicologic pathology 2000;28(4):540-7.
2000: Imazawa T; Nishikawa A; Todate A; Furukawa F; Onodera H; Mitsumori K; Hirose M; Hayashi Y
Dual effects of prolonged ACTH stimulation on 4-hydroxyaminoquinoline 1-oxide-induced adrenocortical lesions in rats.
Toxicologic pathology 2000;28(4):535-9.
2000: Yasuhara K; Kobayashi H; Shimamura Y; Koujitani T; Onodera H; Takagi H; Hirose M; Mitsumori K
Toxicity and blood concentrations of xylazine and its metabolite, 2,6-dimethylaniline, in rats after single or continuous oral administrations.
The Journal of toxicological sciences 2000;25(2):105-13.
2000: Mitsumori K; Onodera H; Shimo T; Yasuhara K; Takagi H; Koujitani T; Hirose M; Maruyama C; Wakana S
Rapid induction of uterine tumors with p53 point mutations in heterozygous p53-deficient CBA mice given a single intraperitoneal administration of N-ethyl-N-nitrosourea.
Carcinogenesis 2000;21(5):1039-42.
2000: Koujitani T; Yasuhara K; Usui T; Nomura T; Onodera H; Takagi H; Hirose M; Mitsumori K
Lack of susceptibility of transgenic mice carrying the human c-Ha-ras proto-oncogene (rasH2 mice) to phenolphthalein in a 6-month carcinogenicity study.
Cancer letters 2000;152(2):211-6.
2000: Imazawa T; Mitsumori K; Kitajima S; Onodera H; Tamura T; Takahashi M; Hirose M
Time course of ultrastructural changes and immunoelectron microscopic localization of neurocalcin in motor endplates of the lumbrical muscles of rats given a single administration of 2,5-di(tert-butyl)-1,4-hydroquinone.
Acta neuropathologica 2000;99(2):109-16.
2000: Takizawa T; Yasuhara K; Mitsumori K; Onodera H; Koujitani T; Tamura T; Takagi H; Hirose M
[A 90-day repeated dose oral toxicity study of magnesium chloride in F344 rats]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 2000;(118):63-70.
1999: Hiratsuka H; Satoh S i; Satoh M; Nishijima M; Katsuki Y; Suzuki J; Nakagawa J i; Sumiyoshi M; Shibutani M; Mitsumori K; Tanaka-Kagawa T; Ando M
Tissue distribution of cadmium in rats given minimum amounts of cadmium-polluted rice or cadmium chloride for 8 months.
Toxicology and applied pharmacology 1999;160(2):183-91.
1999: Shoda T; Mitsumori K; Onodera H; Toyoda K; Uneyama C; Imazawa T; Hirose M
The relationship between decrease in Cx32 and induction of P450 isozymes in the early phase of clofibrate hepatocarcinogenesis in the rat.
Archives of toxicology 1999;73(7):373-80.
1999: Shoda T; Onodera H; Takeda M; Uneyama C; Imazawa T; Takegawa K; Yasuhara K; Watanabe T; Hirose M; Mitsumori K
Liver tumor promoting effects of fenbendazole in rats.
Toxicologic pathology 1999;27(5):553-62.
1999: Tamura T; Mitsumori K; Onodera H; Takahashi M; Funakoshi T; Yasuhara K; Takegawa K; Takagi H; Hirose M
Time course observation of thyroid proliferative lesions and serum levels of related hormones in rats treated with kojic acid after DHPN initiation.
The Journal of toxicological sciences 1999;24(3):145-55.
1999: Koujitani T; Yasuhara K; Kobayashi H; Shimada A; Onodera H; Takagi H; Hirose M; Mitsumori K
Tumor-promoting activity of 2,6-dimethylaniline in a two-stage nasal carcinogenesis model in N-bis(2-hydroxypropyl)nitrosamine-treated rats.
Cancer letters 1999;142(2):161-71.
1999: Tamura T; Mitsumori K; Onodera H; Fujimoto N; Yasuhara K; Takegawa K; Takahashi M
Inhibition of thyroid iodine uptake and organification in rats treated with kojic acid.
Toxicological sciences : an official journal of the Society of Toxicology 1999;47(2):170-5.
1999: Mitsumori K; Onodera H; Takahashi M; Funakoshi T; Tamura T; Yasuhara K; Takegawa K; Takahashi M
Promoting effects of kojic acid due to serum TSH elevation resulting from reduced serum thyroid hormone levels on development of thyroid proliferative lesions in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.
Carcinogenesis 1999;20(1):173-6.
1999: Takagi H; Onodera H; Yun L; Yasuhara K; Koujitani T; Mitsumori K; Hirose M
[13-week subchronic oral toxicity study of ammonium sulfate in rats]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 1999;(117):108-14.
1999: Yun L; Onodera H; Takagi H; Koujitani T; Yasuhara K; Mitsumori K; Hirose M
[A 13-week subchronic oral toxicity study of Perilla extracts in F344 rats]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 1999;(117):104-7.
1998: Mitsumori K
A Japanese view on a global toxicology testing program before ICH1 and after ICH4.
Toxicology letters 1998;102-103():557-60.
1998: Okamiya H; Mitsumori K; Onodera H; Ito S; Imazawa T; Yasuhara K; Takahashi M
Mechanistic study on liver tumor promoting effects of piperonyl butoxide in rats.
Archives of toxicology 1998;72(11):744-50.
1998: Mitsumori K; Shibutani M; Sato S; Onodera H; Nakagawa J; Hayashi Y; Ando M
Relationship between the development of hepato-renal toxicity and cadmium accumulation in rats given minimum to large amounts of cadmium chloride in the long-term: preliminary study.
Archives of toxicology 1998;72(9):545-52.
1998: Ando M; Hiratsuka H; Nakagawa J; Sato S; Hayashi Y; Mitsumori K
Cadmium accumulation in rats treated orally with cadmium chloride for 8 months.
The Journal of toxicological sciences 1998;23(3):243-8.
1998: Takegawa K; Mitsumori K; Onodera H; Yasuhara K; Takahashi M; Yanai T; Masegi T; Hayashi Y
Immunohistochemical studies of TSH-producing cells in the pituitary and expression of growth factors in thyroidal proliferative lesions in rats treated with thiourea and excess vitamin A.
The Journal of toxicological sciences 1998;23(3):213-21.
1998: Mitsumori K; Yasuhara K; Mori I; Hayashi S; Shimo T; Onodera H; Nomura T; Hayashi Y
Pulmonary fibrosis caused by N-methyl-N-nitrosourethane inhibits lung tumorigenesis by urethane in transgenic mice carrying the human prototype c-Ha-ras gene.
Cancer letters 1998;129(2):181-90.
1998: Mitsumori K; Koizumi H; Nomura T; Yamamoto S
Pathological features of spontaneous and induced tumors in transgenic mice carrying a human prototype c-Ha-ras gene used for six-month carcinogenicity studies.
Toxicologic pathology 1998;26(4):520-31.
1998: Shoda T; Mitsumori K; Imazawa T; Toyoda K; Tamura T; Takada K; Takahashi M
A spontaneous seminal vesicle adenocarcinoma in an aged F344 rat.
Toxicologic pathology 1998;26(3):448-51.
1998: Takegawa K; Mitsumori K; Onodera H; Yasuhara K; Kitaura K; Shimo T; Takahashi M
Induction of squamous cell carcinomas in the salivary glands of rats by potassium iodide.
Japanese journal of cancer research : Gann 1998;89(2):105-9.
1998: Yamamoto S; Urano K; Koizumi H; Wakana S; Hioki K; Mitsumori K; Kurokawa Y; Hayashi Y; Nomura T
Validation of transgenic mice carrying the human prototype c-Ha-ras gene as a bioassay model for rapid carcinogenicity testing.
Environmental health perspectives 1998;106 Suppl 1():57-69.
1998: Mitsumori K; Imazawa T; Onodera H; Takahashi M; Kitajima S; Inoue T; Kurokawa Y
Ultrastructural changes in motor endplates of the lumbrical muscles of rats induced by a microsomal Ca2+ ATPase inhibitor, 2,5-di(tert-butyl)-1,4-hydroquinone.
Archives of toxicology 1998;72(2):115-8.
1997: Yasuhara K; Mitsumori K; Shimo T; Onodera H; Takahashi M; Hayashi Y
Mice with focal pulmonary fibrosis caused by monocrotaline are insensitive to urethane induction of lung tumorigenesis.
Toxicologic pathology 1997;25(6):574-81.
1997: Mitsumori K; Wakana S; Yamamoto S; Kodama Y; Yasuhara K; Nomura T; Hayashi Y; Maronpot R R
Susceptibility of transgenic mice carrying human prototype c-Ha-ras gene in a short-term carcinogenicity study of vinyl carbamate and ras gene analyses of the induced tumors.
Molecular carcinogenesis 1997;20(3):298-307.
1997: Mitsumori K; Onodera H; Shoda T; Uneyama C; Imazawa T; Takegawa K; Yasuhara K; Watanabe T; Takahashi M
Liver tumour-promoting effects of oxfendazole in rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(8):799-806.
1997: Yasuhara K; Shimo T; Mitsumori K; Onodera H; Kitaura K; Takahashi M
Lack of carcinogenicity of cyanoguanidine in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1997;35(5):475-80.
1997: Yamamoto S; Hayashi Y; Mitsumori K; Nomura T
Rapid carcinogenicity testing system with transgenic mice harboring human prototype c-HRAS gene.
Laboratory animal science 1997;47(2):121-6.
1997: Takagi H; Yasuhara K; Mitsumori K; Onodera H; Takegawa K; Takahashi M
[A 13-week subacute oral toxicity study of pectin digests in rats]
Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 1997;(115):119-24.
1997: Takegawa K; Mitsumori K; Onodera H; Mutai M; Kitaura K; Takahashi M; Uneyama C; Yasuhara K; Takahashi M; Yanai T; Masegi T; Hayashi Y
UDP-GT involvement in the enhancement of cell proliferation in thyroid follicular cell proliferative lesions in rats treated with thiourea and vitamin A.
Archives of toxicology 1997;71(11):661-7.
1996: Mitsumori K; Nishikawa A
Assessment of carcinogenicity using transgenic animals.
The Journal of toxicological sciences 1996;21(5):479-82.
1996: Yamamoto S; Mitsumori K; Kodama Y; Matsunuma N; Manabe S; Okamiya H; Suzuki H; Fukuda T; Sakamaki Y; Sunaga M; Nomura G; Hioki K; Wakana S; Nomura T; Hayashi Y
Rapid induction of more malignant tumors by various genotoxic carcinogens in transgenic mice harboring a human prototype c-Ha-ras gene than in control non-transgenic mice.
Carcinogenesis 1996;17(11):2455-61.
1996: Yasuhara K; Mitsumori K; Imazawa T; Yoshimura H; Onodera H; Takegawa K; Takahashi M; Shirai W; Hayashi Y
Ultrastructure and cell proliferative activities of karyomegalic alveolar epithelial cells in early pulmonary inflammatory lesions of Syrian golden hamsters induced by N-methyl-N-nitrosourethane.
The Journal of veterinary medical science / the Japanese Society of Veterinary Science 1996;58(9):825-31.
1996: Mitsumori K; Onodera H; Takahashi M; Shimo T; Yasuhara K; Takegawa K; Takahashi M; Hayashi Y
Promoting effect of large amounts of vitamin A on cell proliferation of thyroid proliferative lesions induced by simultaneous treatment with thiourea.
Cancer letters 1996;103(1):19-31.
1996: Takegawa K; Mitsumori K; Onodera H; Shimo T; Takahashi M; Yasuhara K; Takahashi M
[Modifying effects of goitrogens on the tumor development in the liver and lung of rats]
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1996;(114):33-7.
1996: Onodera H; Mitsumori K; Uneyama C; Yasuhara K; Takegawa K; Takahashi M
[Intensity of liver tumor promotion effects in rats given repeated oral administrations of benzimidazole compounds]
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1996;(114):21-6.
1996: Mitsumori K; Takegawa K; Shimo T; Onodera H; Yasuhara K; Takahashi M
Morphometric and immunohistochemical studies on atrophic changes in lympho-hematopoietic organs of rats treated with piperonyl butoxide or subjected to dietary restriction.
Archives of toxicology 1996;70(12):809-14.
1995: Yasuhara K; Mitsumori K; Yoshimura H; Imazawa T; Hayashi S; Onodera H; Takahashi M; Hayashi Y
Relationship between the development of pulmonary fibrosis and lung tumors in Syrian golden hamsters induced by N-methyl-N-nitrosourethane.
Toxicologic pathology 1995;23(5):551-9.
1995: Matsui H; Mitsumori K; Yasuhara K; Onodera H; Shimo T; Takahashi M
Morphological evaluation of cyclophosphamide testicular toxicity in rats using quantitative morphometry of spermatogenic cycle stages.
The Journal of toxicological sciences 1995;20(4):407-14.
1995: Mitsumori K; Onodera H; Takahashi M; Shimo T; Yasuhara K; Kitaura K; Takahashi M; Hayashi Y
Effect of thyroid stimulating hormone on the development and progression of rat thyroid follicular cell tumors.
Cancer letters 1995;92(2):193-202.
1995: Hayashi S; Mitsumori K; Imaida K; Imazawa T; Yasuhara K; Uneyama C; Hayashi Y
Establishment of an animal model for pulmonary fibrosis in mice using monocrotaline.
Toxicologic pathology 1995;23(1):63-71.
1995: Takegawa K; Yasuhara K; Mitsumori K; Onodera H; Shimo T; Takahashi M
[Toxicity in rats fed diet containing iron lactate for 26 weeks]
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1995;(113):58-63.
1994: Onodera H; Kitaura K; Mitsumori K; Yoshida J; Yasuhara K; Shimo T; Takahashi M; Hayashi Y
Study on the carcinogenicity of tannic acid in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1994;32(12):1101-6.
1994: Onodera H; Mitsumori K; Takahashi M; Shimo T; Yasuhara K; Kitaura K; Takahashi M; Hayashi Y
Thyroid proliferative lesions induced by anti-thyroid drugs in rats are not always accompanied by sustained increases in serum TSH.
The Journal of toxicological sciences 1994;19(4):227-34.
1994: Shimo T; Mitsumori K; Onodera H; Yasuhara K; Takahashi M; Takahashi M; Ueno Y; Hayashi Y
Time course observation of thyroid proliferative lesions and serum TSH levels in rats treated with thiourea after DHPN initiation.
Cancer letters 1994;85(2):141-9.
1994: Mitsumori K; Yasuhara K; Yoshimura H; Uneyama C; Imazawa T; Onodera H; Hayashi Y
Experimental induction of pulmonary fibrosis in Syrian golden hamsters by N-methyl-N-nitrosourethane.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 1994;46(4-5):287-95.
1994: Mitsumori K; Kodama Y; Uchida O; Takada K; Saito M; Naito K; Tanaka S; Kurokawa Y; Usami M; Kawashima K
Confirmation study, using nitrobenzene, of the Combined Repeat Dose and Reproductive/Developmental Toxicity Test protocol proposed by the Organization for Economic Cooperation and Development (OECD).
The Journal of toxicological sciences 1994;19(3):141-9.
1994: Shimo T; Mitsumori K; Onodera H; Yasuhara K; Kitaura K; Takahashi M; Kanno J; Hayashi Y
Synergistic effects of phenobarbital and thiourea on proliferative lesions in the rat liver.
Cancer letters 1994;81(1):45-52.
1994: Sawada J; Kikuchi Y; Shibutani M; Mitsumori K; Inoue K; Kasahara T
Induction of metallothionein in astrocytes by cytokines and heavy metals.
Biological signals 1994;3(3):157-68.
1994: Sato M; Furukawa F; Nishikawa A; Mitsumori K; Imazawa T; Takahashi M
Analysis of proliferative activity in renal lesions induced by N-nitrosobis(2-oxopropyl)amine (BOP) in male Syrian golden hamsters.
Cancer letters 1994;79(1):91-9.
1994: Imazawa T; Furukawa F; Shibutani M; Mitsumori K; Sato M; Hayashi Y; Takahashi M
Correlation between nucleolar organizer regions and cell proliferation in pancreatic acinar cell proliferative lesions in rats.
Pancreas 1994;9(2):219-24.
1994: Onodera H; Mitsumori K; Yasuhara K; Shimo T; Kurokawa N; Takahashi M
[13-week subchronic oral toxicity study of isopropyl p-hydroxybenzoate in F344 rats]
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1994;(112):82-8.
1994: Mitsumori K; Furukawa F; Sato M; Yoshimura H; Imazawa T; Nishikawa A; Takahashi M
Promoting effects of ethinyl estradiol on development of renal proliferative lesions induced by N-nitrosobis (2-oxopropyl)amine in female Syrian golden hamsters.
Journal of cancer research and clinical oncology 1994;120(3):131-6.
1994: Shibutani M; Mitsumori K; Okeda R; Imazawa T; Maekawa A; Hatanaka H; Takahashi M; Inoue K; Hayashi Y
Evidence for an origin of ethyl-nitrosourea-induced rat central nervous system tumors from pluripotent germinal neuroepithelium.
Acta neuropathologica 1994;87(3):293-301.
1993: Shibutani M; Maekawa A; Okeda R; Mitsumori K; Imazawa T; Yoshida J; Onodera H; Hayashi Y
An experimental model for anaplastic astrocytomas and glioblastoma using adult F344 rats and N-methyl-N-nitrosourea.
Acta pathologica japonica 1993;43(9):464-74.
1993: Takahashi M; Toyoda K; Aze Y; Furuta K; Mitsumori K; Hayashi Y
The rat urinary bladder as a new target of heterocyclic amine carcinogenicity: tumor induction by 3-amino-1-methyl-5H-pyrido[4,3-b]indole acetate.
Japanese journal of cancer research : Gann 1993;84(8):852-8.
1993: Aze Y; Toyoda K; Furukawa F; Mitsumori K; Takahashi M
Enhancing effect of ethanol on esophageal tumor development in rats by initiation of diethylnitrosamine.
Carcinogenesis 1993;14(1):37-40.
1993: Ogasawara H; Mitsumori K; Onodera H; Imazawa T; Shibutani M; Takahashi M; Ward J M; Maekawa A
Spontaneous histiocytic sarcoma with possible origin from the bone marrow and lymph node in Donryu and F-344 rats.
Toxicologic pathology 1993;21(1):63-70.
1992: Toyoda K; Imaida K; Mitsumori K; Sato H; Maekawa A; Onodera H; Takahashi M
Correlation between cataract and retinopathy due to lighting in F344 rats used in a long-term carcinogenicity study.
Journal of toxicology and environmental health 1992;37(4):495-509.
1992: Sato M; Furukawa F; Toyoda K; Mitsumori K; Nishikawa A; Takahashi M
Lack of carcinogenicity of ferric chloride in F344 rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1992;30(10):837-42.
1992: Matsushima Y; Onodera H; Nagaoka T; Mitsumori K; Lu J; Maekawa A
Promoting effects of 6-mercaptopurine on carcinogenesis in various organs of F344 rats.
Cancer letters 1992;66(2):147-53.
1992: Nishikawa A; Furukawa F; Imazawa T; Yoshimura H; Mitsumori K; Takahashi M
Effects of caffeine, nicotine, ethanol and sodium selenite on pancreatic carcinogenesis in hamsters after initiation with N-nitrosobis(2-oxopropyl)amine.
Carcinogenesis 1992;13(8):1379-82.
1992: Takahashi M; Imaida K; Mitsumori K; Okamiya H; Shinoda K; Yoshimura H; Furukawa F; Hayashi Y
Promoting effects of cigarette smoke on the respiratory tract carcinogenesis of Syrian golden hamsters treated with diethylnitrosamine.
Carcinogenesis 1992;13(4):569-72.
1991: Onodera H; Matsushima Y; Uneyama C; Shibutani M; Mitsumori K; Maekawa A; Hayashi Y
[Dose-response relationship of promotion by phenobarbital in rat two-stage hepatocarcinogenesis]
Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 1991;(109):55-60.
1990: Maekawa A; Mitsumori K
Spontaneous occurrence and chemical induction of neurogenic tumors in rats--influence of host factors and specificity of chemical structure.
Critical reviews in toxicology 1990;20(4):287-310.

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