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Takeshi Miwa

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Daisuke Kamimura; Yutaka Komiyama; Issei Komuro; Toshiaki Mano; Toshio Matsuda; Takeshi Miwa; Tomohito Ohtani; Yosuke Omori; Yasushi Sakata; Hakuo Takahashi; Yasuharu Takeda; Shunsuke Tamaki; Yasumasa Tsukamoto; Satoshi Umemura; Akemichi Baba; Kazuharu Furutani; Masamichi Yoshika; Kazuhiro Yamamoto
Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction.
Tomohito Ohtani; Toshiaki Mano; Shungo Hikoso; Yasushi Sakata; Mayu Nishio; Yasuharu Takeda; Kinya Otsu; Takeshi Miwa; Tohru Masuyama; Masatsugu Hori; Kazuhiro Yamamoto
Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure.
Mayu Nishio; Yasushi Sakata; Toshiaki Mano; Tomohito Ohtani; Yasuharu Takeda; Takeshi Miwa; Masatsugu Hori; Tohru Masuyama; Takashi Kondo; Kazuhiro Yamamoto
Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats.

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All Publications

2012: Daisuke Kamimura; Yutaka Komiyama; Issei Komuro; Toshiaki Mano; Toshio Matsuda; Takeshi Miwa; Tomohito Ohtani; Yosuke Omori; Yasushi Sakata; Hakuo Takahashi; Yasuharu Takeda; Shunsuke Tamaki; Yasumasa Tsukamoto; Satoshi Umemura; Akemichi Baba; Kazuharu Furutani; Masamichi Yoshika; Kazuhiro Yamamoto
Ca2+ entry mode of Na+/Ca2+ exchanger as a new therapeutic target for heart failure with preserved ejection fraction.
European heart journal 2012;33(11):1408-16.
2009: Tomohito Ohtani; Toshiaki Mano; Shungo Hikoso; Yasushi Sakata; Mayu Nishio; Yasuharu Takeda; Kinya Otsu; Takeshi Miwa; Tohru Masuyama; Masatsugu Hori; Kazuhiro Yamamoto
Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure.
Journal of hypertension 2009;27(5):1074-83.
2008: Mayu Nishio; Yasushi Sakata; Toshiaki Mano; Tomohito Ohtani; Yasuharu Takeda; Takeshi Miwa; Masatsugu Hori; Tohru Masuyama; Takashi Kondo; Kazuhiro Yamamoto
Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats.
European journal of heart failure 2008;10(5):446-53.
2007: Mayu Nishio; Yasushi Sakata; Toshiaki Mano; Junichi Yoshida; Tomohito Ohtani; Yasuharu Takeda; Takeshi Miwa; Tohru Masuyama; Kazuhiro Yamamoto; Masatsugu Hori
Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failure.
Journal of hypertension 2007;25(2):455-61.
2007: Tomohito Ohtani; Miho Ohta; Kazuhiro Yamamoto; Toshiaki Mano; Yasushi Sakata; Mayu Nishio; Yasuharu Takeda; Junichi Yoshida; Takeshi Miwa; Mitsuhiro Okamoto; Tohru Masuyama; Yasuki Nonaka; Masatsugu Hori
Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker.
American journal of physiology. Regulatory, integrative and comparative physiology 2007;292(2):R946-54.
2006: Masanobu Takeji; Toshiki Moriyama; Susumu Oseto; Noritaka Kawada; Masatsugu Hori; Enyu Imai; Takeshi Miwa
Smooth muscle alpha-actin deficiency in myofibroblasts leads to enhanced renal tissue fibrosis.
The Journal of biological chemistry 2006;281(52):40193-200.
2005: Junichi Yoshida; Kazuhiro Yamamoto; Toshiaki Mano; Yasushi Sakata; Mayu Nishio; Tomohito Ohtani; Masatsugu Hori; Takeshi Miwa; Tohru Masuyama
Different effects of long- and short-acting loop diuretics on survival rate in Dahl high-salt heart failure model rats.
Cardiovascular research 2005;68(1):118-27.
2005: Kazuhiro Yamamoto; Toshiaki Mano; Junichi Yoshida; Yasushi Sakata; Nagahiro Nishikawa; Mayu Nishio; Tomohito Ohtani; Masatsugu Hori; Takeshi Miwa; Tohru Masuyama
ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure.
Journal of hypertension 2005;23(2):393-400.
2004: Masanobu Takeji; Noritaka Kawada; Toshiki Moriyama; Katsuyuki Nagatoya; Susumu Oseto; Shizuo Akira; Masatsugu Hori; Enyu Imai; Takeshi Miwa
CCAAT/Enhancer-binding protein delta contributes to myofibroblast transdifferentiation and renal disease progression.
Journal of the American Society of Nephrology : JASN 2004;15(9):2383-90.
2004: Kazuhiro Yamamoto; Yoshito Takahashi; Toshiaki Mano; Yasushi Sakata; Nagahiro Nishikawa; Junichi Yoshida; Yuichi Oishi; Masatsugu Hori; Takeshi Miwa; Shintaro Inoue; Tohru Masuyama
N-methylethanolamine attenuates cardiac fibrosis and improves diastolic function: inhibition of phospholipase D as a possible mechanism.
European heart journal 2004;25(14):1221-9.
2004: Yasushi Sakata; Kazuhiro Yamamoto; Toshiaki Mano; Nagahiro Nishikawa; Junichi Yoshida; Masatsugu Hori; Takeshi Miwa; Tohru Masuyama
Activation of matrix metalloproteinases precedes left ventricular remodeling in hypertensive heart failure rats: its inhibition as a primary effect of Angiotensin-converting enzyme inhibitor.
Circulation 2004;109(17):2143-9.
2004: Junichi Yoshida; Kazuhiro Yamamoto; Toshiaki Mano; Yasushi Sakata; Nagahiro Nishikawa; Mayu Nishio; Tomohito Ohtani; Takeshi Miwa; Masatsugu Hori; Tohru Masuyama
AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure.
Hypertension 2004;43(3):686-91.
2003: Yasushi Sakata; Kazuhiro Yamamoto; Toshiaki Mano; Nagahiro Nishikawa; Junichi Yoshida; Hiroyuki Nakayama; Kinya Otsu; Keiichiro Suzuki; Michihiko Tada; Masatsugu Hori; Takeshi Miwa; Tohru Masuyama
Angiotensin II type 1 receptor blockade prevents diastolic heart failure through modulation of Ca(2+) regulatory proteins and extracellular matrix.
Journal of hypertension 2003;21(9):1737-45.
2003: Nagahiro Nishikawa; Kazuhiro Yamamoto; Yasushi Sakata; Toshiaki Mano; Junichi Yoshida; Takeshi Miwa; Hiroshi Takeda; Masatsugu Hori; Tohru Masuyama
Differential activation of matrix metalloproteinases in heart failure with and without ventricular dilatation.
Cardiovascular research 2003;57(3):766-74.
2003: Yasushi Sakata; Kazuhiro Yamamoto; Toshiaki Mano; Nagahiro Nishikawa; Junichi Yoshida; Takeshi Miwa; Masatsugu Hori; Tohru Masuyama
Temocapril prevents transition to diastolic heart failure in rats even if initiated after appearance of LV hypertrophy and diastolic dysfunction.
Cardiovascular research 2003;57(3):757-65.
2003: Junichi Yoshida; Kazuhiro Yamamoto; Toshiaki Mano; Yasushi Sakata; Nagahiro Nishikawa; Takeshi Miwa; Masatsugu Hori; Tohru Masuyama
Angiotensin II type 1 and endothelin type A receptor antagonists modulate the extracellular matrix regulatory system differently in diastolic heart failure.
Journal of hypertension 2003;21(2):437-44.
2002: Kazuhiro Yamamoto; Tohru Masuyama; Yasushi Sakata; Nagahiro Nishikawa; Toshiaki Mano; Junichi Yoshida; Takeshi Miwa; Motoaki Sugawara; Yukihiro Yamaguchi; Tomomi Ookawara; Keiichiro Suzuki; Masatsugu Hori
Myocardial stiffness is determined by ventricular fibrosis, but not by compensatory or excessive hypertrophy in hypertensive heart.
Cardiovascular research 2002;55(1):76-82.
2001: Nagahiro Nishikawa; Tohru Masuyama; Kazuhiro Yamamoto; Yasushi Sakata; Toshiaki Mano; Takeshi Miwa; Motoaki Sugawara; Masatsugu Hori
Long-term administration of amlodipine prevents decompensation to diastolic heart failure in hypertensive rats.
Journal of the American College of Cardiology 2001;38(5):1539-45.
2001: Yasushi Sakata; Kazuhiro Yamamoto; Tohru Masuyama; Toshiaki Mano; Nagahiro Nishikawa; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Ventricular production of natriuretic peptides and ventricular structural remodeling in hypertensive heart failure.
Journal of hypertension 2001;19(10):1905-12.
2001: Yasushi Sakata; Tohru Masuyama; Kazuhiro Yamamoto; Reiko Doi; Toshiaki Mano; Tsunehiko Kuzuya; Takeshi Miwa; Hiroshi Takeda; Masatsugu Hori
Renin angiotensin system-dependent hypertrophy as a contributor to heart failure in hypertensive rats: different characteristics from renin angiotensin system-independent hypertrophy.
Journal of the American College of Cardiology 2001;37(1):293-9.
2000: Yasushi Sakata; Tohru Masuyama; Kazuhiro Yamamoto; Nagahiro Nishikawa; H Yamamoto; H Kondo; Keiko Ono; Kinya Otsu; Tsunehiko Kuzuya; Takeshi Miwa; Hiroshi Takeda; E Miyamoto; Masatsugu Hori
Calcineurin inhibitor attenuates left ventricular hypertrophy, leading to prevention of heart failure in hypertensive rats.
Circulation 2000;102(18):2269-75.
2000: Kazuhiro Yamamoto; Tohru Masuyama; Yasushi Sakata; Toshiaki Mano; Nagahiro Nishikawa; H Kondo; Noriyuki Akehi; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Roles of renin-angiotensin and endothelin systems in development of diastolic heart failure in hypertensive hearts.
Cardiovascular research 2000;47(2):274-83.
2000: Kazuhiro Yamamoto; Tohru Masuyama; Yasushi Sakata; Reiko Doi; Keiko Ono; Toshiaki Mano; H Kondo; Tsunehiko Kuzuya; Takeshi Miwa; Masatsugu Hori
Local neurohumoral regulation in the transition to isolated diastolic heart failure in hypertensive heart disease: absence of AT1 receptor downregulation and 'overdrive' of the endothelin system.
Cardiovascular research 2000;46(3):421-32.
2000: Reiko Doi; Tohru Masuyama; Kazuhiro Yamamoto; Y Doi; Toshiaki Mano; Yasushi Sakata; Keiko Ono; Tsunehiko Kuzuya; S Hirota; T Koyama; Takeshi Miwa; Masatsugu Hori
Development of different phenotypes of hypertensive heart failure: systolic versus diastolic failure in Dahl salt-sensitive rats.
Journal of hypertension 2000;18(1):111-20.