Shuji Miyagawa

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Saito Shunsuke; Matsumiya Goro; Fukushima Norihide; Sakaguchi Taichi; Fujita Tomoyuki; Ueno Takayoshi; Miyagawa Shuji; Yamauchi Amane; Sawa Yoshiki
Successful treatment of cardiogenic shock caused by humoral cardiac allograft rejection.
Xu Hengjie; Firdawes Sabere; Yamamoto Aki; Zhao Yu; Ihara Yoshiyuki; Uehara Shuichiro; Matsunami Katsuyoshi; Otsuka Hideaki; Fukuzawa Masahiro; Miyagawa Shuji
Effects of blocking the chemokine receptors, CCR5 and CXCR3, With TAK-779 in a rat small intestinal transplantation model.
Okura Eiji; Ishimaru Aiko; Yamamoto Aki; Nakatsu Shino; Shirakura Ryota; Okabe Masaru; Sawa Yoshiki; Fukuzawa Masahiro; Okumura Meinoshin; Miyagawa Shuji
Differential human serum-mediated neutralization of PERV released from pig cells transfected with variants of hDAF.

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2009: Saito Shunsuke; Matsumiya Goro; Fukushima Norihide; Sakaguchi Taichi; Fujita Tomoyuki; Ueno Takayoshi; Miyagawa Shuji; Yamauchi Amane; Sawa Yoshiki
Successful treatment of cardiogenic shock caused by humoral cardiac allograft rejection.
Circulation journal : official journal of the Japanese Circulation Society 2009;73(5):970-3.
2008: Xu Hengjie; Firdawes Sabere; Yamamoto Aki; Zhao Yu; Ihara Yoshiyuki; Uehara Shuichiro; Matsunami Katsuyoshi; Otsuka Hideaki; Fukuzawa Masahiro; Miyagawa Shuji
Effects of blocking the chemokine receptors, CCR5 and CXCR3, With TAK-779 in a rat small intestinal transplantation model.
Transplantation 2008;86(12):1810-7.
2008: Okura Eiji; Ishimaru Aiko; Yamamoto Aki; Nakatsu Shino; Shirakura Ryota; Okabe Masaru; Sawa Yoshiki; Fukuzawa Masahiro; Okumura Meinoshin; Miyagawa Shuji
Differential human serum-mediated neutralization of PERV released from pig cells transfected with variants of hDAF.
Xenotransplantation 2008;15(6):365-73.
2008: Xu H; Firdawes S; Yamamoto A; Matsunami K; Ishimaru A; Kondo A; Fukuzawa M; Miyagawa S
Cloning and in vitro antiapoptotic effects of pig FLIPs.
Transplantation proceedings 2008;40(8):2779-81.
2008: Matsunami K; Otsuka H; Xu H; Firdawes S; Yamamoto A; Ishimaru A; Fukuzawa M; Miyagawa S
Molecular cloning of pig Rad51, Rad52, and Rad54 genes, which are involved in homologous recombination machinery.
Transplantation proceedings 2008;40(8):2776-8.
2008: Matsunami K; Otsuka H; Xu H; Furidaus S; Ishimaru A; Fukuzawa M; Miyagawa S
Isolation and sequencing of pig Blm and Ubl-1/SUMO-1 genes that relate to the recombination machinery.
Transplantation proceedings 2008;40(8):2773-5.
2008: Fujimura Tatsuya; Takahagi Yoichi; Shigehisa Tamotsu; Nagashima Hiroshi; Miyagawa Shuji; Shirakura Ryota; Murakami Hiroshi
Production of alpha 1,3-galactosyltransferase gene-deficient pigs by somatic cell nuclear transfer: a novel selection method for gal alpha 1,3-Gal antigen-deficient cells.
Molecular reproduction and development 2008;75(9):1372-8.
2008: Matsunami Katsuyoshi; Okura Eiji; Uchida Hiroko; Otsuka Hideaki; Fukuzawa Masahiro; Miyagawa Shuji
Identification of amino acid positions involved in HLA-E expression.
Journal of biochemistry 2008;143(5):641-7.
2008: Nakahata Kengo; Matsunami Katsuyoshi; Kobayashi Chizuko; Omori Takeshi; Xu Hengjie; Firdawes Sabere; Fukuzawa Masahiro; Miyagawa Shuji
Analysis of the serine protease function of porcine factor I produced by liver cells for xenotransplantation.
Transplant immunology 2008;19(1):30-6.
2008: Xu H; Kitano E; Sato Y; Kobayashi C; Firdawes S; Ishimaru A; Yamamoto A; Kitamura H; Fukuzawa M; Miyagawa S
Investigation of cynomolgus monkey complement.
Transplantation proceedings 2008;40(2):607-8.
2008: Fujimura T; Miyagawa S; Takahagi Y; Shigehisa T; Murakami H
Prevalence of porcine endogenous retroviruses in domestic, minature, and genetically modified pigs in Japan.
Transplantation proceedings 2008;40(2):594-5.
2008: Xu Hengjie; Kitano Etsuko; Sato Yu; Kobayashi Chizuko; Firdawes Sabere; Kitamura Hajime; Fukuzawa Masahiro; Miyagawa Shuji
Studies of monkey complement: measurement of cynomolgus monkey CH50, ACH50, C4, C2 and C3.
Xenotransplantation 2008;15(1):14-9.
2007: Miyagawa Shuji
[Clinical xenotransplantation]
Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 2007;30(3):174-84.
2007: Ihara Yoshiyuki; Miyagawa Shuji; Hasegawa Toshimichi; Kimura Takuya; Xu Hengjie; Fukuzawa Masahiro
Effect of blocking the mucosal addressin cell adhesion molecule-1 (MAdCAM-1) in a rat small intestinal transplantation model.
Transplant immunology 2007;17(4):271-7.
2007: Matsunami Katsuyoshi; Kondo Akihiro; Nakatsu Shino; Omori Takeshi; Nakagawa Takatoshi; Otsuka Hideaki; Fukuzawa Masahiro; Miyagawa Shuji
Cloning of pig serine proteinase inhibitor 9 and its use in protecting against apoptosis.
Transplant international : official journal of the European Society for Organ Transplantation 2007;20(5):453-9.
2006: Koboyashi C; Matsunami K; Omori T; Nakahata K; Nakatsu S; Xu H; Gao C; Ihara Y; Fukuzawa M; Miyagawa S
Cross-species function of the pig C1 esterase inhibitor.
Transplantation proceedings 2006;38(10):3321-2.
2006: Omori Takeshi; Nishida Toshirou; Komoda Hiroshi; Fumimoto Yuichi; Ito Toshinori; Sawa Yoshiki; Gao Congxiao; Nakatsu Shino; Shirakura Ryota; Miyagawa Shuji
A study of the xenoantigenicity of neonatal porcine islet-like cell clusters (NPCC) and the efficiency of adenovirus-mediated DAF (CD55) expression.
Xenotransplantation 2006;13(5):455-64.
2006: Miyagawa Shuji; Fukuta Daisuke; Kitano Etsuko; Kobayashi Chizuko; Fumimoto Yuichi; Shirasu Akio; Hattori Hiroyuki; Shirakura Ryota; Fukuzawa Masahiro
Effect of tandem forms of DAF(CD55) on complement-mediated xenogeneic cell lysis.
Xenotransplantation 2006;13(5):433-9.
2006: Kobayashi Chizuko; Matsunami Katsuyoshi; Omori Takeshi; Nakatsu Shino; Nakahata Kengo; Xu Hengjie; Shirakura Ryota; Fukuzawa Masahiro; Miyagawa Shuji
Features of a newly cloned pig C1 esterase inhibitor.
Journal of biochemistry 2006;140(3):421-7.
2006: Matsunami Katsuyoshi; Kusama Tamiko; Okura Eiji; Shirakura Ryota; Fukuzawa Masahiro; Miyagawa Shuji
Involvement of position-147 for HLA-E expression.
Biochemical and biophysical research communications 2006;347(3):692-7.
2006: Miyagawa Shuji; Nakatsu Shino; Hazama Kenji; Nakagawa Takatoshi; Kondo Akihiro; Matsunami Katsuyoshi; Yamamoto Aki; Yamada Junko; Miyazawa Takayuki; Shirakura Ryota
A novel strategy for preventing PERV transmission to human cells by remodeling the viral envelope glycoprotein.
Xenotransplantation 2006;13(3):258-63.
2006: Matsunami Katsuyoshi; Miyagawa Shuji; Nakagawa Kenji; Otsuka Hideaki; Shirakura Ryota
Molecular cloning of pigGnT-I and I.2: an application to xenotransplantation.
Biochemical and biophysical research communications 2006;343(3):677-83.
2005: Takahagi Yoichi; Fujimura Tatsuya; Miyagawa Shuji; Nagashima Hiroshi; Shigehisa Tamotsu; Shirakura Ryota; Murakami Hiroshi
Production of alpha 1,3-galactosyltransferase gene knockout pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III.
Molecular reproduction and development 2005;71(3):331-8.
2005: Komoda Hiroshi; Miyagawa Shuji; Omori Takeshi; Takahagi Yoichi; Murakami Hiroshi; Shigehisa Tamotsu; Ito Toshinori; Matsuda Hikaru; Shirakura Ryota
Survival of adult islet grafts from transgenic pigs with N-acetylglucosaminyltransferase-III (GnT-III) in cynomolgus monkeys.
Xenotransplantation 2005;12(3):209-16.
2005: Miyagawa Shuji
[Complement regulatory proteins]
Nippon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():274-8.
2005: Miyagawa Shuji; Nakatsu Shino; Nakagawa Takatoshi; Kondo Akihiro; Matsunami Katsuyoshi; Hazama Kenji; Yamada Junko; Tomonaga Keizo; Miyazawa Takayuki; Shirakura Ryota
Prevention of PERV infections in pig to human xenotransplantation by the RNA interference silences gene.
Journal of biochemistry 2005;137(4):503-8.
2005: Hazama K; Miyagawa S; Yamamoto A; Kubo T; Miyazawa T; Tomonaga K; Watanabe R; Okumura M; Matsuda H; Shirakura R
The effect of complement regulatory protein expression on pig endothelial cells to porcine endogenous retrovirus lyses by human sera.
Transplantation proceedings 2005;37(1):503-5.
2004: Fujita Tatsuya; Miyagawa Shuji; Ezoe Kyori; Saito Tamotsu; Sato Noriyuki; Takahagi Yoichi; Murakami Hiroshi; Matsunami Katsuyoshi; Shirakura Ryota; Taniguchi Naoyuki
Skin graft of double transgenic pigs of N-acetylglucosaminyltransferase III (GnT-III) and DAF (CD55) genes survived in cynomolgus monkey for 31 days.
Transplant immunology 2004;13(4):259-64.
2004: Miyagawa Shuji; Kubo Tomoko; Matsunami Katsuyoshi; Kusama Tamiko; Beppu Keiko; Nozaki Hiroshi; Moritan Toshiyuki; Ahn Curie; Kim Jae Young; Fukuta Daisuke; Shirakura Ryota
Delta-short consensus repeat 4-decay accelerating factor (DAF: CD55) inhibits complement-mediated cytolysis but not NK cell-mediated cytolysis.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(6):3945-52.
2004: Komoda Hiroshi; Miyagawa Shuji; Kubo Tomoko; Kitano Etsuko; Kitamura Hajime; Omori Takeshi; Ito Toshinori; Matsuda Hikaru; Shirakura Ryota
A study of the xenoantigenicity of adult pig islets cells.
Xenotransplantation 2004;11(3):237-46.
2004: Fukuta Daisuke; Miyagawa Shuji; Kubo Tomoko; Kusama Tamiko; Shirasu Akio; Hattori Hiroyuki; Shirakura Ryota
Only the light chain is sufficient for the serine protease function of the membrane bound form of factor I on a xeno-surface.
Transplant immunology 2004;12(2):109-14.
2004: Fujimura Tatsuya; Kurome Mayuko; Murakami Hiroshi; Takahagi Yoichi; Matsunami Katsuyoshi; Shimanuki Shinichi; Suzuki Kohei; Miyagawa Shuji; Shirakura Ryota; Shigehisa Tamotsu; Nagashima Hiroshi
Cloning of the transgenic pigs expressing human decay accelerating factor and N-acetylglucosaminyltransferase III.
Cloning and stem cells 2004;6(3):294-301.
2003: Kurihara Takashi; Miyazawa Takayuki; Miyagawa Shuji; Tomonaga Keizo; Hazama Kenji; Yamada Junko; Shirakura Ryota; Matsuura Yoshiharu
Sensitivity to human serum of gammaretroviruses produced from pig endothelial cells transduced with glycosyltransferase genes.
Xenotransplantation 2003;10(6):562-8.
2003: Hazama Kenji; Miyagawa Shuji; Miyazawa Takayuki; Yamada Junko; Tomonaga Keizo; Ota Mitsunori; Matsuda Hikaru; Shirakura Ryota
The significance of N-linked glycosylation in pig endogenous retrovirus infectivity.
Biochemical and biophysical research communications 2003;310(2):327-33.
2003: Fukuta Daisuke; Miyagawa Shuji; Kubo Tomoko; Matsunami Katsuyoshi; Shirasu Akio; Hattori Hiroyuki; Shirakura Ryota
Effect of hybrid complement regulatory proteins on xenogeneic cells.
Biochemical and biophysical research communications 2003;306(2):476-82.
2003: Miyagawa Shuji; Nakai Rie; Matsunami Katsuyoshi; Kusama Tamiko; Shirakura Ryota
Co-effect of HLA-G1 and glycosyltransferases in reducing NK cell-mediated pig endothelial cell lysis.
Transplant immunology 2003;11(2):147-53.
2003: Fukuta Daisuke; Miyagawa Shuji; Yamada Mako; Matsunami Katsuyoshi; Kurihara Takashi; Shirasu Akio; Hattori Hiroyuki; Shirakura Ryota
Effect of various forms of the C1 esterase inhibitor (C1-INH) and DAF on complement mediated xenogeneic cell lysis.
Xenotransplantation 2003;10(2):132-41.
2003: Matsunami K; Miyagawa S; Fukuta D; Shirakura R
Functional analysis of HSV-gC1 on swine endothelial cells: potential for xenotransplantation.
Transplantation proceedings 2003;35(1):538-9.
2003: Kusama T; Miyagawa S; Moritan T; Kubo T; Yamada M; Sata H; Fukuta D; Matsunami K; Shirakura R
Downregulation of NK cell-mediated swine endothelial cell lysis by DAF (CD55).
Transplantation proceedings 2003;35(1):529-30.
2003: Fukuta D; Miyagawa S; Yamada M; Matsunami K; Kurihara T; Shirasu A; Hattori H; Shirakura R
Various forms of DAF (CD55) and C1 esterase inhibitor.
Transplantation proceedings 2003;35(1):519-20.
2003: Fujita T; Machida K; Matsumoto Y; Saito T; Sato N; Takahagi Y; Murakami H; Miyagawa S; Shirakura R; Taniguchi N
Cynomolgus monkey did not hyperacutely reject skin xenograft of N-acetylglucosaminyltransferase III gene transgenic pig.
Transplantation proceedings 2003;35(1):518.
2003: Takahagi Y; Miyagawa S; Murakami H; Matsunami K; Fujimura T; Shigehisa T; Shirakura R
Transgenic pigs expressing both human decay-accelerating factor and N-acetylglucosaminyltransferase III.
Transplantation proceedings 2003;35(1):516-7.
2002: Matsunami Katsuyoshi; Miyagawa Shuji; Nakai Rie; Yamada Mako; Shirakura Ryota
Modulation of the leader peptide sequence of the HLA-E gene up-regulates its expression and down-regulates natural killer cell-mediated swine endothelial cell lysis.
Transplantation 2002;73(10):1582-9.
2002: Matsunami Katsuyoshi; Miyagawa Shuji; Fukuta Daisuke; Shirakura Ryota
Regulation of complement-mediated swine endothelial cell lysis by herpes simplex virus glycoprotein, gC1.
Journal of biochemistry 2002;131(5):745-9.
2002: Koma Masaru; Miyagawa Shuji; Honke Koichi; Nakai Rie; Miyoshi Shinichirou; Ohta Mitsunori; Matsuda Hikaru; Shirakura Ryota; Taniguchi Naoyuki
The possibility of reducing xenoantigen levels with a novel gal 3'-sulfotransferase (GP3ST).
Journal of biochemistry 2002;131(4):517-22.
2002: Murakami Hiroshi; Nagashima Hiroshi; Takahagi Yoichi; Miyagawa Shuji; Fujimura Tatsuya; Toyomura Koji; Nakai Rie; Yamada Mako; Kurihara Takashi; Shigehisa Tamotsu; Okabe Masaru; Seya Tsukasa; Shirakura Ryota; Kinoshita Taroh
Transgenic pigs expressing human decay-accelerating factor regulated by porcine MCP gene promoter.
Molecular reproduction and development 2002;61(3):302-11.
2001: Miyagawa S; Matsunami K; Yoshitatsu M; Mikata S; Matsuda H; Shirakura R
Attempts to prepare suitable complement regulatory molecules for clinical xenotransplantation.
Journal of cardiac surgery 2001;16(6):429-38.
2001: Miyagawa S; Sawa Y; Fukushima N; Nishimura M; Matsumiya G; Taketani S; Horiguchi K; Ohtake S; Matsuda H
Analysis of sympathetic nerve activity in end-stage cardiomyopathy patients receiving left ventricular support.
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 2001;20(11):1181-7.
2001: Matsunami K; Miyagawa S; Nakai R; Murase A; Shirakura R
The possible use of HLA-G1 and G3 in the inhibition of NK cell-mediated swine endothelial cell lysis.
Clinical and experimental immunology 2001;126(1):165-72.
2001: Miyagawa S; Murakami H; Takahagi Y; Nakai R; Yamada M; Murase A; Koyota S; Koma M; Matsunami K; Fukuta D; Fujimura T; Shigehisa T; Okabe M; Nagashima H; Shirakura R; Taniguchi N
Remodeling of the major pig xenoantigen by N-acetylglucosaminyltransferase III in transgenic pig.
The Journal of biological chemistry 2001;276(42):39310-9.
2001: Koyota S; Ikeda Y; Miyagawa S; Ihara H; Koma M; Honke K; Shirakura R; Taniguchi N
Down-regulation of the alpha-Gal epitope expression in N-glycans of swine endothelial cells by transfection with the N-acetylglucosaminyltransferase III gene. Modulation of the biosynthesis of terminal structures by a bisecting GlcNAc.
The Journal of biological chemistry 2001;276(35):32867-74.
2001: Miyagawa S; Yamada M; Matsunami K; Koresawa Y; Ikawa M; Okabe M; Shirakura R
A synthetic dDAF (CD55) gene based on optimal codon usage for transgenic animals.
Journal of biochemistry 2001;129(5):795-801.
2001: Yamada M; Miyagawa S; Matsunami K; Koresawa Y; Kurihara T; Ikawa M; Okabe M; Shirakura R
A codon exchange DAF is a powerful material for xenografting.
Transplantation proceedings 2001;33(1-2):744-5.
2001: Miyagawa S; Murakami H; Murase A; Nakai R; Koma M; Koyota S; Matsunami K; Takahagi Y; Fujimura T; Shigehisa T; Nagashima H; Shirakura R; Taniguchi N
Transgenic pigs with human N-acetylglucosaminyltransferase III.
Transplantation proceedings 2001;33(1-2):742-3.
2000: Koresawa Y; Miyagawa S; Ikawa M; Matsunami K; Yamada M; Okabe M; Shirakura R
A new Cre recombinase gene based on optimal codon usage in mammals: a powerful material for organ-specific gene targeting.
Transplantation proceedings 2000;32(7):2516-7.
2000: Koma M; Miyagawa S; Koyota S; Yoshitatsu M; Miyoshi S; Matsuda H; Tsuji S; Shirakura R; Taniguchi N
Effects of Gal beta 1,4 GlcNAc alpha 2,6-D-Sialyl transferase on swine xenoantigen.
Transplantation proceedings 2000;32(7):2509-10.
2000: Murase A; Miyagawa S; Koma M; Ikeda Y; Honke K; Wakamiya N; Tuji S; Shirakura R; Taniguchi N
An attempt to downregulate the Hanganutziu-Deicher antigen by overexpression of glycosyltransferases.
Transplantation proceedings 2000;32(7):2507-8.
2000: Murakami H; Nagashima H; Takahagi Y; Fujimura T; Miyagawa S; Okabe M; Seya T; Shigehisa T; Taniguchi N; Shirakura R; Kinoshita T
Production of transgenic pigs expressing human DAF (CD55) regulated by the porcine MCP gene promoter.
Transplantation proceedings 2000;32(7):2505-6.
2000: Yoshitatsu M; Ohtake S; Sawa Y; Fukushima N; Nishimura M; Sakakida S; Ichikawa H; Satou H; Matsumiya G; Kobayashi Y; Horiguchi K; Miyagawa S; Shirakura R; Matsuda H
Assessment of autonomic reinnervation of cardiac grafts by analysis of heart rate variability.
Transplantation proceedings 2000;32(7):2383-5.
2000: Matsunami K; Miyagawa S; Nakai R; Yamada M; Shirakura R
The regulation of natural killer-mediated swine endothelial cell lysis by HLA-G (G1 and G3).
Transplantation proceedings 2000;32(7):2087-8.
2000: Miyagawa S; Nagashima H
[Development of donor animals for xenotransplantation]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(13 Suppl):2313-9.
2000: Matsunami K; Miyagawa S; Nakai R; Yamada M; Shirakura R
Protection against natural killer-mediated swine endothelial cell lysis by HLA-G and HLA-E.
Transplantation proceedings 2000;32(5):939-40.
2000: Nakai R; Miyagawa S; Matsunami K; Yamada M; Koma M; Taniguchi N; Shirakura R
Effect of the remodeling of a glycoantigen on natural killer cell-mediated direct cytotoxicity.
Transplantation proceedings 2000;32(5):929-30.
2000: Yoshitatsu M; Miyagawa S; Murase A; Matsunami K; Yamada M; Sawa Y; Ohtake S; Matsuda H; Shirakura R
Prevention of hyperacute rejection by phosphatidylinositol-anchored factor I.
Transplantation proceedings 2000;32(5):905-6.
2000: Matsunami K; Miyagawa S; Yamada M; Nakai R; Yoshitatsu M; Shirakura R
A surface-bound form of human C1 esterase inhibitor on xenografts: the complement regulatory function.
Transplantation proceedings 2000;32(5):901-2.
2000: Koma M; Miyagawa S; Honke K; Ikeda Y; Koyota S; Murase A; Tsuji S; Miyoshi S; Matsuda H; Shirakura R; Taniguchi N
Effect of various glycosyltransferases on the swine xenoantigen.
Transplantation proceedings 2000;32(5):855.
2000: Koma M; Miyagawa S; Honke K; Ikeda Y; Koyota S; Miyoshi S; Matsuda H; Tsuji S; Shirakura R; Taniguchi N
Reduction of the major xenoantigen on glycosphingolipids of swine endothelial cells by various glycosyltransferases.
Glycobiology 2000;10(7):745-51.
2000: Murakami H; Takahagi Y; Yoshitatsu M; Miyagawa S; Fujimura T; Toyomura K; Shigehisa T; Shirakura R; Kinoshita T
Porcine MCP gene promoter directs high level expression of human DAF (CD55) in transgenic mice.
Immunobiology 2000;201(5):583-97.
2000: Matsunami K; Miyagawa S; Yamada M; Yoshitatsu M; Shirakura R
A surface-bound form of human C1 esterase inhibitor improves xenograft rejection.
Transplantation 2000;69(5):749-55.
2000: Koresawa Y; Miyagawa S; Ikawa M; Matsunami K; Yamada M; Shirakura R; Okabe M
Synthesis of a new Cre recombinase gene based on optimal codon usage for mammalian systems.
Journal of biochemistry 2000;127(3):367-72.
1999: Miyagawa S; Nakai R; Yamada M; Tanemura M; Ikeda Y; Taniguchi N; Shirakura R
Regulation of natural killer cell-mediated swine endothelial cell lysis through genetic remodeling of a glycoantigen.
Journal of biochemistry 1999;126(6):1067-73.
1999: Yoshitatsu M; Miyagawa S; Mikata S; Matsunami K; Yamada M; Koresawa Y; Sawa Y; Ohtake S; Matsuda H; Shirakura R
Expression of PI-anchored mini-factor H on porcine endothelial cells: potential use in xenotransplantation.
Transplantation proceedings 1999;31(7):2812-3.
1999: Yoshitatsu M; Miyagawa S; Mikata S; Matsunami K; Yamada M; Murase A; Sawa Y; Ohtake S; Matsuda H; Shirakura R
Function of human factor H and I on xenosurface.
Biochemical and biophysical research communications 1999;265(2):556-62.
1999: Miyagawa S; Tanemura M; Koyota S; Koma M; Ikeda Y; Shirakura R; Taniguchi N
Masking and reduction of the Galactose-alpha1,3-Galactose (alpha-Gal) epitope, the major xenoantigen in swine, by the glycosyltransferase gene transfection.
Biochemical and biophysical research communications 1999;264(3):611-4.
1998: Miyagawa S; Shirakura R; Taniguchi N
[Downregulation of alpha-galactosyl epitope in xenograft]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1998;43(16 Suppl):2618-24.
1998: Shirakura R; Miyagawa S
[Present and future of heart transplantation in Japan and the world]
Nippon Geka Gakkai zasshi 1998;99(11):749-53.
1998: Mikata S; Miyagawa S; Yoshitatsu M; Ikawa M; Okabe M; Matsuda H; Shirakura R
Prevention of hyperacute rejection by phosphatidylinositol-anchored mini-complement receptor type 1.
Transplant immunology 1998;6(2):107-10.
1998: Tanemura M; Miyagawa S; Koyota S; Koma M; Matsuda H; Tsuji S; Shirakura R; Taniguchi N
Reduction of the major swine xenoantigen, the alpha-galactosyl epitope by transfection of the alpha2,3-sialyltransferase gene.
The Journal of biological chemistry 1998;273(26):16421-5.
1998: Mikata S; Miyagawa S; Kamiike W; Ito T; Matsuda H; Iwata K; Nagasawa S; Seya T; Shirakura R
New approach to prevent complement activation on xenografts: effects of a surface-bound form of human C4b binding protein.
Transplantation proceedings 1998;30(1):65-6.
1997: Tanemura M; Miyagawa S; Ihara Y; Matsuda H; Shirakura R; Taniguchi N
Significant downregulation of the major swine xenoantigen by N-acetylglucosaminyltransferase III gene transfection.
Biochemical and biophysical research communications 1997;235(2):359-64.
1997: Miyagawa S; Mikata S; Tanaka H; Ikawa M; Kominami K; Seya T; Nishimune Y; Shirakura R; Okabe M
The regulation of membrane cofactor protein (CD46) expression by the 3' untranslated region in transgenic mice.
Biochemical and biophysical research communications 1997;233(3):829-33.
1997: Izutani H; Miyagawa S; Mikata S; Shirakura R; Matsuda H
Essential initial immunostimulation in graft coronary arteriosclerosis induction detected by retransplantation technique in rats: the participation of T cell subsets.
Transplant immunology 1997;5(1):11-5.
1997: Miyagawa S; Ikawa M; Kominami K; Tanaka H; Mikata S; Matsuda H; Seya T; Shirakura R; Okabe M
The regulation of membrane cofactor protein (CD46) expression in transgenic mice: the importance of the first 125 BP of the 3' untranslated region.
Transplantation proceedings 1997;29(1-2):941-2.
1997: Tanemura M; Miyagawa S; Ihara Y; Nishikawa A; Suzuki M; Yamamura K; Matsuda H; Shirakura R; Taniguchi N
Suppression of the xenoantigen Gal alpha(1,3)Gal by N-acetylglucosaminyltransferase III (GnT-III) in transgenic mice.
Transplantation proceedings 1997;29(1-2):895-6.
1997: Tanemura M; Miyagawa S; Ihara Y; Mikata S; Matsuda H; Shirakura R; Taniguchi N
Reduction of the major swine xenoantigen Gal alpha (1,3)Gal by transfection of N-acetylglucosaminyl transferase III (GnT-III) gene.
Transplantation proceedings 1997;29(1-2):891-2.
1997: Izutani H; Miyagawa S; Shirakura R; Tanemura M; Mikata S; K-Sakakida S; Fukushima N; Nakata S; Matsuda H
Recipient macrophage depletion reduces the severity of graft coronary arteriosclerosis in the rat retransplantation model.
Transplantation proceedings 1997;29(1-2):861-2.
1996: Izutani H; Miyagawa S; Shirakura R; Mikata S; Tanemura M; Fukushima N; Nakata S; Matsuda H
Effect of recipient T cell subset depletion on graft coronary arteriosclerosis induction in the rat retransplant model.
Transplantation proceedings 1996;28(3):1828-9.
1996: Miyagawa S; Mikata S; Shirakura R; Matsuda H; Nagasawa S; Terados A; Hatanaka M; Matsumoto M; Seya T
C5b-8 step lysis of swine endothelial cells by human complement and functional feature of transfected CD59.
Scandinavian journal of immunology 1996;43(4):361-6.
1996: Miyagawa S; Shirakura R; Mikata S; Tanemura M; Fukushima N; Matsuda H; Terado A; Hatanaka M; Matsumoto M; Seya T
Functional feature of C5b-8-step lysis of swine endothelial cell- transfected CD59.
Transplantation proceedings 1996;28(2):597-8.
1996: Miyagawa S; Ikawa M; Kominami K; Yoshimura Y; Tanaka H; Mikata S; Shirakura R; Matsuda H; Yanagi Y; Seya T; Okabe M
Difference of expression levels between gene technological product delta CYT-MCP(CD46) and intact MCP(CD46) in transgenic mice.
Transplantation proceedings 1996;28(2):585-6.
1996: Miyagawa S; Mikata M; Matsuda H; Ikawa M; Okabe M; Nagasawa S; Matsumoto M; Seya T; Shirakura R
In vitro and in vivo studies to prevent hyperacute rejection.
Transplantation proceedings 1996;28(2):1031-3.
1995: Izutani H; Miyagawa S; Shirakura R; Matsumiya G; Nakata S; Shimazaki Y; Matsuda H
Evidence that graft coronary arteriosclerosis begins in the early phase after transplantation and progresses without chronic immunoreaction. Histopathological analysis using a retransplantation model.
Transplantation 1995;60(10):1073-9.
1995: Seya T; Hara T; Iwata K; Kuriyama S; Hasegawa T; Nagase Y; Miyagawa S; Matsumoto M; Hatanaka M; Atkinson J P
Purification and functional properties of soluble forms of membrane cofactor protein (CD46) of complement: identification of forms increased in cancer patients' sera.
International immunology 1995;7(5):727-36.
1995: Izutani H; Miyagawa S; Matsumiya G; Nakata S; Shimazaki Y; Matsuda H; Shirakura R
Graft coronary arteriosclerosis in rat heart transplant model with FK 506 short-term administration.
Transplantation proceedings 1995;27(1):579-81.
1995: Miyagawa S; Shirakura R; Nakata S; Izutani H; Matsuda H; Iwata K; Nagasawa S; Terado A; Hatanaka M; Matsumoto M
Effect of transfected MACIF (CD59) on complement-mediated swine endothelial cell lysis, compared with those of membrane cofactor protein (CD46) and decay-accelerating factor (CD55).
Transplantation proceedings 1995;27(1):328-9.
1994: Fukushima N; Shirakura R; Nakata S; Kaneko M; Miyagawa S; Naka Y; Chang J C; Matsumiya G; Nakano S; Matsuda H
Study of efficacies of leukocyte-depleted terminal blood cardioplegia in 24-hour preserved hearts.
The Annals of thoracic surgery 1994;58(6):1651-6.
1994: Miyagawa S; Shirakura R; Iwata K; Nakata S; Matsumiya G; Izutani H; Matsuda H; Terado A; Matsumoto M; Nagasawa S
Effects of transfected complement regulatory proteins, MCP, DAF, and MCP/DAE hybrid, on complement-mediated swine endothelial cell lysis.
Transplantation 1994;58(7):834-40.
1994: Nakata S; Shirakura R; Ito T; Fukuzawa M; Miyagawa S; Yamamoto S; Nozaki T; Matsumiya G; Izutani H; Matsuda H
Immunosuppressive mechanisms of deoxymethylspergualin and FK 506 on in vitro cytotoxic T lymphocytes.
Transplantation proceedings 1994;26(4):1930-2.
1994: Matsumiya G; Shirakura R; Miyagawa S; Izutani H; Nakata S; Matsuda H
Assessment of T-cell subsets involved in antibody production and cell-mediated cytotoxicity in rat-to-mouse cardiac xenotransplantation.
Transplantation proceedings 1994;26(3):1214-6.
1994: Matsumiya G; Shirakura R; Miyagawa S; Izutani H; Sawa Y; Nakata S; Matsuda H
Analysis of rejection mechanism in the rat to mouse cardiac xenotransplantation. Role and characteristics of anti-endothelial cell antibodies.
Transplantation 1994;57(11):1653-60.
1994: Miyagawa S; Shirakura R; Izutani H; Matsumiya G; Nakata S; Matsuda H; Iwata K; Nagasawa S; Terado A; Matsumoto M
Effect of transfectant molecules, MCP, DAF, and MCP/DAF hybrid on xenogeneic vascular endothelium.
Transplantation proceedings 1994;26(3):1253-4.
1994: Miyagawa S; Shirakura R; Matsumiya G; Nakata S; Matsuda H; Hatanaka M; Matsumoto M; Seya T
Possibility of prevention of hyperacute rejection by DAF and CD59 in xenotransplantation.
Transplantation proceedings 1994;26(3):1235-8.
1994: Matsumiya G; Shirakura R; Miyagawa S; Izutani H; Nakata S; Shimazaki Y; Nakano S; Matsuda H
Role of CD4+ T cells in the rat to mouse cardiac xenotransplantation.
Transplant international : official journal of the European Society for Organ Transplantation 1994;7 Suppl 1():S654-9.
1993: Shirakura R; Kamiike W; Matsumura A; Miyagawa S; Fukushima N; Hatanaka N; Chang J C; Shimizu S; Sueki H; Amemiya A
Multiorgan procurement from non-heart-beating donors by use of Osaka University cocktail, Osaka rinse solution, and the portable cardiopulmonary bypass machine.
Transplantation proceedings 1993;25(6):3093-4.
1993: Hara T; Matsumoto M; Fukumori Y; Miyagawa S; Hatanaka M; Kinoshita T; Seya T; Akedo H
A monoclonal antibody against human decay-accelerating factor (DAF, CD55), D17, which lacks reactivity with semen-DAF.
Immunology letters 1993;37(2-3):145-52.
1993: Miyagawa S; Shirakura R; Matsumiya G; Nakata S; Matsuda H; Hatanaka M; Matsumoto M; Kitamura H; Seya T
Test for ability of decay-accelerating factor (DAF, CD55) and CD59 to alleviate complement-mediated damage of xeno-erythrocytes.
Scandinavian journal of immunology 1993;38(1):37-44.
1993: Miyagawa S; Shirakura R; Matsumiya G; Fukushima N; Nakata S; Matsuda H; Matsumoto M; Kitamura H; Seya T
Prolonging discordant xenograft survival with anticomplement reagents K76COOH and FUT175.
Transplantation 1993;55(4):709-13.
1993: Matsumiya G; Shirakura R; Miyagawa S; Nakata S; Nakano S; Kinoshita T; Matsuda H
Inhibitory effect of the complement receptor-specific monoclonal antibody on the induced antibody response and the role of CD4+ and CD8+ T-cells in the rat to mouse xenotransplantation.
Transplantation proceedings 1993;25(1 Pt 1):402-4.
1992: Fukushima N; Shirakura R; Nakata S; Kaneko M; Miyagawa S; Kitagawa S; Chang J; Amemiya A; Matsumiya G; Matsuda H
Effects of terminal cardioplegia with leukocyte-depleted blood on myocardial adenosine triphosphate in heart grafts preserved for 24 hours.
Transplantation proceedings 1992;24(4):1489-90.
1992: Shirakura R; Matsuda H; Nakata S; Kaneko M; Miyagawa S; Fukushima N; Kitagawa S; Naka Y; Matsumiya G; Nakano S
A new method to harvest multiple organs from non-heart-beating donors by use of a percutaneous cardiopulmonary support machine.
Transplantation proceedings 1992;24(4):1329-30.
1992: Shirakura R; Matsuda H; Nakano S; Nakata S; Kaneko M; Takami H; Miyagawa S; Fukushima N; Kitagawa S; Naka Y
Myocardial energy metabolism in asphyxiated canine hearts preserved for 24 hours.
Transplantation 1992;53(6):1215-8.
1992: Miyagawa S; Shirakura R; Matsumiya G; Kitagawa S; Fukushima N; Nakata S; Nakano S; Kitamura H; Matsumoto M; Seya T
Effect of anticomplement reagents, K-76 COOH and FUT175, on discordant xenograft survival.
Transplantation proceedings 1992;24(2):483-4.
1992: Fukushima N; Shirakura R; Nakata S; Ito T; Miyagawa S; Matsumiya G; Matsuda H
[The effect of nafamstat mesilate (FUT175) on hyperacute rejection in discordant cardiac xenograft (guinea pig to rat): preliminary report]
Nippon Geka Gakkai zasshi 1992;93(2):218.
1991: Seya T; Okada M; Hara T; Matsumoto M; Miyagawa S; Oshimura M
Human complement regulatory proteins expressed on mouse A9 cells containing a human chromosome 1.
Immunology 1991;74(4):719-24.
1990: Shirakura R; Matsuda H; Nakata S; Kaneko M; Kawaguchi A; Miyagawa S; Fukushima N; Kitagawa S; Naka Y; Kawashima Y
Prolonged preservation of cadaver heart with Belzer UW solution: 24-hour storage system for asphyxiated canine hearts.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1990;22(4):197-205.
1989: Naka Y; Hirose H; Matsuda H; Nakano S; Shirakura R; Kawaguchi A; Miyamoto Y; Miyagawa S; Fukushima N; Kawashima Y
Prevention of pulmonary edema in autoperfusing heart-lung preparation by FUT-175 and leukocyte depletion.
Transplantation proceedings 1989;21(1 Pt 2):1353-6.
1989: Shirakura R; Hirose H; Matsuda H; Nakano S; Nakata S; Ohtani M; Kawaguti A; Miyagawa S; Takami H; Naka Y
Resuscitation and preservation of agonally arrested hearts for transplantation: a study of 24 hour stored canine hearts.
Transplantation proceedings 1989;21(1 Pt 2):1347-9.
1989: Miyagawa S; Hirose H; Shirakura R; Nakata S; Naka Y; Kitagawa S; Nakano S; Matsumoto M; Seya T; Kitamura H
The mechanism of discordant xenograft rejection.
Transplantation proceedings 1989;21(1 Pt 1):520-1.
1989: Naka Y; Hirose H; Matsuda H; Shirakura R; Miyagawa S; Fukushima N; Kawashima Y
Prevention of pulmonary edema developing in autoperfusing heart-lung preparation by leukocyte depletion.
European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 1989;3(4):355-8.
1988: Miyagawa S; Hirose H; Shirakura R; Naka Y; Nakata S; Kawashima Y; Seya T; Matsumoto M; Uenaka A; Kitamura H
The mechanism of discordant xenograft rejection.
Transplantation 1988;46(6):825-30.

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