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Atsushi Miyajima

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Hinako M Takase; Yasuhiro Takikawa; Ting Wang; Shizuo Akira; Seitaro Ino; Tohru Itoh; Takehiko Koji; Atsushi Miyajima
FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.
Fuyuki F Inagaki; Natsuko F Inagaki; Norihiro Kokudo; Naoki Oyaizu; Yuya Sato; Kiyotoshi Sekiguchi; Minoru Tanaka; Tomoki Yagai; Atsushi Miyajima
Nephronectin is upregulated in acute and chronic hepatitis and aggravates liver injury by recruiting CD4 positive cells.
Takayoshi Bando; Tomoko Hisaoka; Tadasuke Komori; Atsushi Miyajima; Yoshihiro Morikawa; Emiko Senba
Expression pattern of leucine-rich repeat neuronal protein 4 in adult mouse dorsal root ganglia.

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2013: Hinako M Takase; Yasuhiro Takikawa; Ting Wang; Shizuo Akira; Seitaro Ino; Tohru Itoh; Takehiko Koji; Atsushi Miyajima
FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration.
Genes & development 2013;27(2):169-81.
2013: Fuyuki F Inagaki; Natsuko F Inagaki; Norihiro Kokudo; Naoki Oyaizu; Yuya Sato; Kiyotoshi Sekiguchi; Minoru Tanaka; Tomoki Yagai; Atsushi Miyajima
Nephronectin is upregulated in acute and chronic hepatitis and aggravates liver injury by recruiting CD4 positive cells.
Biochemical and biophysical research communications 2013;430(2):751-6.
2012: Takayoshi Bando; Tomoko Hisaoka; Tadasuke Komori; Atsushi Miyajima; Yoshihiro Morikawa; Emiko Senba
Expression pattern of leucine-rich repeat neuronal protein 4 in adult mouse dorsal root ganglia.
Neuroscience letters 2012;531(1):24-9.
2012: Kazunori Senga; Toshihiro Mitaka; Atsushi Miyajima; Keith E Mostov; Naoki Tanimizu
Grainyhead-like 2 regulates epithelial morphogenesis by establishing functional tight junctions through the organization of a molecular network among claudin3, claudin4, and Rab25.
Molecular biology of the cell 2012;23(15):2845-55.
2012: Yuichiro Miyaoka; Shigeomi Shimizu; Satoko Arakawa; Kazuki Ebato; Hidenori Kato; Atsushi Miyajima
Hypertrophy and unconventional cell division of hepatocytes underlie liver regeneration.
Current biology : CB 2012;22(13):1166-75.
2012: Yoshikazu Hirose; Toru Kanke; Shigeaki Kato; Taketomo Kido; Yen-Rong Chen; Ryozo Nagai; Koji Nakamura; Takashi Nakamura; Satoshi Nishimura; Hidenori Nonaka; Takahiro Ochiya; Eiko Saijou; Keisuke Sekine; Yasuyoshi Sugano; Fumitaka Takeshita; Atsushi Miyajima
Inhibition of Stabilin-2 elevates circulating hyaluronic acid levels and prevents tumor metastasis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(11):4263-8.
2012: Akihide Kamiya; Atsushi Miyajima
Mice with artificial human liver.
Hepatology (Baltimore, Md.) 2012;55(3):974-6.
2011: Minoru Tanaka; Tohru Itoh; Naoki Tanimizu; Atsushi Miyajima
Liver stem/progenitor cells: their characteristics and regulatory mechanisms.
Journal of biochemistry 2011;149(3):231-9.
2011: Hiroki Saito; Masaki Takeuchi; Kazuhiro Chida; Atsushi Miyajima
Generation of glucose-responsive functional islets with a three-dimensional structure from mouse fetal pancreatic cells and iPS cells in vitro.
PloS one 2011;6(12):e28209.
2010: Shumpei Yamauchi; Hiroaki Ito; Atsushi Miyajima
IkappaBeta, a nuclear IkappaB protein, positively regulates the NF-kappaB-mediated expression of proinflammatory cytokines.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(26):11924-9.
2010: Izumi Onitsuka; Minoru Tanaka; Atsushi Miyajima
Characterization and functional analyses of hepatic mesothelial cells in mouse liver development.
Gastroenterology 2010;138(4):1525-35, 1535.e1-6.
2010: Yuichiro Miyaoka; Minoru Tanaka; Toru Imamura; Shinji Takada; Atsushi Miyajima
A novel regulatory mechanism for Fgf18 signaling involving cysteine-rich FGF receptor (Cfr) and delta-like protein (Dlk).
Development (Cambridge, England) 2010;137(1):159-67.
2009: Yoshikazu Hirose; Tohru Itoh; Atsushi Miyajima
Hedgehog signal activation coordinates proliferation and differentiation of fetal liver progenitor cells.
Experimental cell research 2009;315(15):2648-57.
2009: Minoru Tanaka; Mayuko Okabe; Kaori Suzuki; Yoshiko Kamiya; Yuko Tsukahara; Shigeru Saito; Atsushi Miyajima
Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development.
Mechanisms of development 2009;126(8-9):665-76.
2009: Yen-Rong Chen; Keisuke Sekine; Koji Nakamura; Hiroyuki Yanai; Minoru Tanaka; Atsushi Miyajima
Y-box binding protein-1 down-regulates expression of carbamoyl phosphate synthetase-I by suppressing CCAAT enhancer-binding protein-alpha function in mice.
Gastroenterology 2009;137(1):330-40.
2009: Mayuko Okabe; Yuko Tsukahara; Minoru Tanaka; Kaori Suzuki; Shigeru Saito; Yoshiko Kamiya; Tohru Tsujimura; Koji Nakamura; Atsushi Miyajima
Potential hepatic stem cells reside in EpCAM+ cells of normal and injured mouse liver.
Development (Cambridge, England) 2009;136(11):1951-60.
2009: Eiji Esashi; Hiroaki Ito; Ken-ichi Minehata; Shigeru Saito; Yoshihiro Morikawa; Atsushi Miyajima
Oncostatin M deficiency leads to thymic hypoplasia, accumulation of apoptotic thymocytes and glomerulonephritis.
European journal of immunology 2009;39(6):1664-70.
2009: Tohru Itoh; Yoshiko Kamiya; Mayuko Okabe; Minoru Tanaka; Atsushi Miyajima
Inducible expression of Wnt genes during adult hepatic stem/progenitor cell response.
FEBS letters 2009;583(4):777-81.
2008: Hidenori Nonaka; Tetsuro Watabe; Shigeru Saito; Kohei Miyazono; Atsushi Miyajima
Development of stabilin2+ endothelial cells from mouse embryonic stem cells by inhibition of TGFbeta/activin signaling.
Biochemical and biophysical research communications 2008;375(2):256-60.
2008: Akihide Kamiya; Sei Kakinuma; Masafumi Onodera; Atsushi Miyajima; Hiromitsu Nakauchi
Prospero-related homeobox 1 and liver receptor homolog 1 coordinately regulate long-term proliferation of murine fetal hepatoblasts.
Hepatology (Baltimore, Md.) 2008;48(1):252-64.
2008: Kaori Suzuki; Minoru Tanaka; Natsumi Watanabe; Shigeru Saito; Hidenori Nonaka; Atsushi Miyajima
p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver.
Gastroenterology 2008;135(1):270-281.e3.
2008: Yasuyoshi Sugano; Masaki Takeuchi; Ayami Hirata; Hirokazu Matsushita; Toshio Kitamura; Minoru Tanaka; Atsushi Miyajima
Junctional adhesion molecule-A, JAM-A, is a novel cell-surface marker for long-term repopulating hematopoietic stem cells.
Blood 2008;111(3):1167-72.
2007: Eiko Saijou; Tohru Itoh; Kyung-Woon Kim; Shun-ichiro Iemura; Tohru Natsume; Atsushi Miyajima
Nucleocytoplasmic shuttling of the zinc finger protein EZI Is mediated by importin-7-dependent nuclear import and CRM1-independent export mechanisms.
The Journal of biological chemistry 2007;282(44):32327-37.
2007: Takahiro Naiki; Eiko Saijou; Yuichiro Miyaoka; Keisuke Sekine; Atsushi Miyajima
TRB2, a mouse Tribbles ortholog, suppresses adipocyte differentiation by inhibiting AKT and C/EBPbeta.
The Journal of biological chemistry 2007;282(33):24075-82.
2007: Keisuke Sekine; Yen-Rong Chen; Nobuhiko Kojima; Kazuhiro Ogata; Akiyoshi Fukamizu; Atsushi Miyajima
Foxo1 links insulin signaling to C/EBPalpha and regulates gluconeogenesis during liver development.
The EMBO journal 2007;26(15):3607-15.
2007: Hidenori Nonaka; Minoru Tanaka; Kaori Suzuki; Atsushi Miyajima
Development of murine hepatic sinusoidal endothelial cells characterized by the expression of hyaluronan receptors.
Developmental dynamics : an official publication of the American Association of Anatomists 2007;236(8):2258-67.
2007: Natsumi Watanabe; Minoru Tanaka; Kaori Suzuki; Atsushi Kumanogoh; Hitoshi Kikutani; Atsushi Miyajima
Tim2 is expressed in mouse fetal hepatocytes and regulates their differentiation.
Hepatology (Baltimore, Md.) 2007;45(5):1240-9.
2007: Tamaki Kobayashi; Shigeharu Sato; Shinzaburo Takamiya; Kanako Komaki-Yasuda; Kazuhiko Yano; Ayami Hirata; Izumi Onitsuka; Masayuki Hata; Fumika Mi-Ichi; Takeshi Tanaka; Toshiharu Hase; Atsushi Miyajima; Shin-ichiro Kawazu; Yoh-ichi Watanabe; Kiyoshi Kita
Mitochondria and apicoplast of Plasmodium falciparum: behaviour on subcellular fractionation and the implication.
Mitochondrion 2007;7(1-2):125-32.
2007: Fumikiyo Nagawa; Natsuko Kishishita; Kazumichi Shimizu; Satoshi Hirose; Masato Miyoshi; Junnya Nezu; Toshinobu Nishimura; Hirofumi Nishizumi; Yoshimasa Takahashi; Shu-ichi Hashimoto; Masaki Takeuchi; Atsushi Miyajima; Toshitada Takemori; Anthony J Otsuka; Hitoshi Sakano
Antigen-receptor genes of the agnathan lamprey are assembled by a process involving copy choice.
Nature immunology 2007;8(2):206-13.
2006: Yuichiro Miyaoka; Minoru Tanaka; Takahiro Naiki; Atsushi Miyajima
Oncostatin M inhibits adipogenesis through the RAS/ERK and STAT5 signaling pathways.
The Journal of biological chemistry 2006;281(49):37913-20.
2006: Ken-ichi Minehata; Masaki Takeuchi; Yoko Hirabayashi; Tohru Inoue; Peter J Donovan; Minoru Tanaka; Atsushi Miyajima
Oncostatin m maintains the hematopoietic microenvironment and retains hematopoietic progenitors in the bone marrow.
International journal of hematology 2006;84(4):319-27.
2006: Hiroaki Ito; Eiji Esashi; Taishin Akiyama; Jun-ichiro Inoue; Atsushi Miyajima
IL-18 produced by thymic epithelial cells induces development of dendritic cells with CD11b in the fetal thymus.
International immunology 2006;18(8):1253-63.
2006: Hiroko Sano; Tomomi Noguchi; Atsushi Miyajima; Yuichi Hashimoto; Hiroyuki Miyachi
Anti-angiogenic activity of basic-type, selective cyclooxygenase (COX)-1 inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(11):3068-72.
2006: Takahiro Ito; Nagisa Arimitsu; Masaki Takeuchi; Nobuyuki Kawamura; Makiko Nagata; Kayoko Saso; Nobuyoshi Akimitsu; Hiroshi Hamamoto; Shunji Natori; Atsushi Miyajima; Kazuhisa Sekimizu
Transcription elongation factor S-II is required for definitive hematopoiesis.
Molecular and cellular biology 2006;26(8):3194-203.
2005: Tomomi Noguchi; Haruka Fujimoto; Hiroko Sano; Atsushi Miyajima; Hiroyuki Miyachi; Yuichi Hashimoto
Angiogenesis inhibitors derived from thalidomide.
Bioorganic & medicinal chemistry letters 2005;15(24):5509-13.
2005: Nobuhiko Kojima; Nobuyoshi Shiojiri; Yasuyuki Sakai; Atsushi Miyajima
Expression of neuritin during liver maturation and regeneration.
FEBS letters 2005;579(21):4562-6.
2005: Takayoshi Bando; Keisuke Sekine; Shizuka Kobayashi; Ayako M Watabe; Armin Rump; Minoru Tanaka; Yoshikuni Suda; Shigeaki Kato; Yoshihiro Morikawa; Toshiya Manabe; Atsushi Miyajima
Neuronal leucine-rich repeat protein 4 functions in hippocampus-dependent long-lasting memory.
Molecular and cellular biology 2005;25(10):4166-75.
2005: Atsushi Miyajima
[Cytokines and their functions].
Nihon rinsho. Japanese journal of clinical medicine 2005;63 Suppl 4():173-7.
2004: Hidenori Nonaka; Sumio Sugano; Atsushi Miyajima
Serial analysis of gene expression in sinusoidal endothelial cells from normal and injured mouse liver.
Biochemical and biophysical research communications 2004;324(1):15-24.
2004: Eiji Esashi; Hiroaki Ito; Katsuhiko Ishihara; Toshio Hirano; Shigeo Koyasu; Atsushi Miyajima
Development of CD4+ macrophages from intrathymic T cell progenitors is induced by thymic epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(7):4360-7.
2004: Jinlan Jiang; Nobuhiko Kojima; Lei Guo; Katsutoshi Naruse; Makuuchi Masatoshi; Atsushi Miyajima; Weiqun Yan; Yasuyuki Sakai
Efficacy of engineered liver tissue based on poly-L-lactic acid scaffolds and fetal mouse liver cells cultured with oncostatin M, nicotinamide, and dimethyl sulfoxide.
Tissue engineering 2004;10(9-10):1577-86.
2004: Armin Rump; Yoshihiro Morikawa; Minoru Tanaka; Sawako Minami; Naohiko Umesaki; Masaki Takeuchi; Atsushi Miyajima
Binding of ovarian cancer antigen CA125/MUC16 to mesothelin mediates cell adhesion.
The Journal of biological chemistry 2004;279(10):9190-8.
2004: Yoshihiro Morikawa; Shinobu Tamura; Ken-ichi Minehata; Peter J Donovan; Atsushi Miyajima; Emiko Senba
Essential function of oncostatin m in nociceptive neurons of dorsal root ganglia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(8):1941-7.
2003: Minoru Tanaka; Yoko Hirabayashi; Takashi Sekiguchi; Tohru Inoue; Motoya Katsuki; Atsushi Miyajima
Targeted disruption of oncostatin M receptor results in altered hematopoiesis.
Blood 2003;102(9):3154-62.
2003: S Hanada; H Kayano; Jinlan Jiang; Nobuhiko Kojima; Atsushi Miyajima; Akiyoshi Sakoda; Yasuyuki Sakai
Enhanced in vitro maturation of subcultivated fetal human hepatocytes in three dimensional culture using poly-L-lactic acid scaffolds in the presence of oncostatin M.
The International journal of artificial organs 2003;26(10):943-51.
2003: Eiji Esashi; Takashi Sekiguchi; Hiroaki Ito; Shigeo Koyasu; Atsushi Miyajima
Cutting Edge: A possible role for CD4+ thymic macrophages as professional scavengers of apoptotic thymocytes.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(6):2773-7.
2003: Shinobu Tamura; Yoshihiro Morikawa; Atsushi Miyajima; Emiko Senba
Expression of oncostatin M receptor beta in a specific subset of nociceptive sensory neurons.
The European journal of neuroscience 2003;17(11):2287-98.
2003: Minoru Tanaka; Atsushi Miyajima
Oncostatin M, a multifunctional cytokine.
Reviews of physiology, biochemistry and pharmacology 2003;149():39-52.
2002: Koh Nakayama; Kyung-Woon Kim; Atsushi Miyajima
A novel nuclear zinc finger protein EZI enhances nuclear retention and transactivation of STAT3.
The EMBO journal 2002;21(22):6174-84.
2002: Taisei Kinoshita; Atsushi Miyajima
Cytokine regulation of liver development.
Biochimica et biophysica acta 2002;1592(3):303-12.
2002: Shinobu Tamura; Yoshihiro Morikawa; Atsushi Miyajima; Emiko Senba
Expression of oncostatin M in hematopoietic organs.
Developmental dynamics : an official publication of the American Association of Anatomists 2002;225(3):327-31.
2002: Takaaki Matsui; Taisei Kinoshita; Toshio Hirano; Takashi Yokota; Atsushi Miyajima
STAT3 down-regulates the expression of cyclin D during liver development.
The Journal of biological chemistry 2002;277(39):36167-73.
2002: Shinobu Tamura; Yoshihiro Morikawa; Minoru Tanaka; Atsushi Miyajima; Emiko Senba
Developmental expression pattern of oncostatin M receptor beta in mice.
Mechanisms of development 2002;115(1-2):127-31.
2002: Ken-ichi Minehata; Yoh-suke Mukouyama; Takashi Sekiguchi; Takahiko Hara; Atsushi Miyajima
Macrophage colony stimulating factor modulates the development of hematopoiesis by stimulating the differentiation of endothelial cells in the AGM region.
Blood 2002;99(7):2360-8.
2002: Takaaki Matsui; Taisei Kinoshita; Yoshihiro Morikawa; Kazuo Tohya; Motoya Katsuki; Yoshiaki Ito; Akira Kamiya; Atsushi Miyajima
K-Ras mediates cytokine-induced formation of E-cadherin-based adherens junctions during liver development.
The EMBO journal 2002;21(5):1021-30.
2002: Masaki Takeuchi; Takashi Sekiguchi; Takahiko Hara; Taisei Kinoshita; Atsushi Miyajima
Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow.
Blood 2002;99(4):1190-6.
2002: Yasuyuki Sakai; Jinlan Jiang; Nobuhiko Kojima; Taroh Kinoshita; Atsushi Miyajima
Enhanced in vitro maturation of fetal mouse liver cells with oncostatin M, nicotinamide, and dimethyl sulfoxide.
Cell transplantation 2002;11(5):435-41.
2001: R Murakami; Taijiro Tomikawa; Kazuo Shin-Ya; J Shinozaki; Takayuki Kajiura; T Kinoshita; Atsushi Miyajima; Haruo Seto; Yoichi Hayakawa
Ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. I. Production, isolation and biological activity.
The Journal of antibiotics 2001;54(9):710-3.
2001: Taroh Kinoshita; K Nagata; N Sorimachi; H Karasuyama; Takashi Sekiguchi; Atsushi Miyajima
Oncostatin M suppresses generation of lymphoid progenitors in fetal liver by inhibiting the hepatic microenvironment.
Experimental hematology 2001;29(9):1091-7.
2001: Taijiro Tomikawa; Kazuo Shin-Ya; T Kinoshita; Atsushi Miyajima; Haruo Seto; Yoichi Hayakawa
Selective cytotoxicity and stereochemistry of aspochalasin D.
The Journal of antibiotics 2001;54(4):379-81.
2000: Yoshiaki Ito; Takaaki Matsui; Akira Kamiya; Taroh Kinoshita; Atsushi Miyajima
Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and ras pathways during hepatic development.
Hepatology (Baltimore, Md.) 2000;32(6):1370-6.
2000: N Kojima; Taroh Kinoshita; Akira Kamiya; K Nakamura; K Nakashima; T Taga; Atsushi Miyajima
Cell density-dependent regulation of hepatic development by a gp130-independent pathway.
Biochemical and biophysical research communications 2000;277(1):152-8.
2000: Atsushi Miyajima; Taroh Kinoshita; Minoru Tanaka; Akira Kamiya; Yoh-suke Mukouyama; Takahiko Hara
Role of Oncostatin M in hematopoiesis and liver development.
Cytokine & growth factor reviews 2000;11(3):177-83.
2000: K Ariyoshi; Tetsuya Nosaka; K Yamada; M Onishi; Yoshitaka Oka; Atsushi Miyajima; Toshio Kitamura
Constitutive activation of STAT5 by a point mutation in the SH2 domain.
The Journal of biological chemistry 2000;275(32):24407-13.
2000: Taijiro Tomikawa; Kazuo Shin-Ya; Kazuo Furihata; T Kinoshita; Atsushi Miyajima; Haruo Seto; Yoichi Hayakawa
Rasfonin, a new apoptosis inducer in ras-dependent cells from Talaromyces sp.
The Journal of antibiotics 2000;53(8):848-50.
2000: Yoh-suke Mukouyama; N Chiba; Takahiko Hara; H Okada; Yoshiaki Ito; R Kanamaru; Atsushi Miyajima; M Satake; Tomomi Watanabe
The AML1 transcription factor functions to develop and maintain hematogenic precursor cells in the embryonic aorta-gonad-mesonephros region.
Developmental biology 2000;220(1):27-36.
2000: Yoshihiro Morikawa; K Tohya; Shinobu Tamura; M Ichihara; Atsushi Miyajima; Emiko Senba
Expression of interleukin-6 receptor, leukemia inhibitory factor receptor and glycoprotein 130 in the murine cerebellum and neuropathological effect of leukemia inhibitory factor on cerebellar Purkinje cells.
Neuroscience 2000;100(4):841-8.
2000: K Yamada; K Ariyoshi; M Onishi; Atsushi Miyajima; F Hayakawa; M Towatari; H Saito; Yoshitaka Oka; Shigetaka Asano; Tetsuya Nosaka; Toshio Kitamura
Constitutively active STAT5A and STAT5B in vitro and in vivo: mutation of STAT5 is not a frequent cause of leukemogenesis.
International journal of hematology 2000;71(1):46-54.
1999: Takahiko Hara; Y Nakano; Minoru Tanaka; K Tamura; Takashi Sekiguchi; Ken-ichi Minehata; Neal G Copeland; Nancy A Jenkins; M Okabe; H Kogo; Yoh-suke Mukouyama; Atsushi Miyajima
Identification of podocalyxin-like protein 1 as a novel cell surface marker for hemangioblasts in the murine aorta-gonad-mesonephros region.
Immunity 1999;11(5):567-78.
1999: Keiichi I Nakayama; Takahiko Hara; Masahiko Hibi; Toshio Hirano; Atsushi Miyajima
A novel oncostatin M-inducible gene OIG37 forms a gene family with MyD118 and GADD45 and negatively regulates cell growth.
The Journal of biological chemistry 1999;274(35):24766-72.
1999: Yoh-suke Mukouyama; N Chiba; M L Mucenski; M Satake; Atsushi Miyajima; Takahiko Hara; Tomomi Watanabe
Hematopoietic cells in cultures of the murine embryonic aorta-gonad-mesonephros region are induced by c-Myb.
Current biology : CB 1999;9(15):833-6.
1999: Taroh Kinoshita; Takashi Sekiguchi; Ming-Jiang Xu; Yoshiaki Ito; Akira Kamiya; Kunikazu Tsuji; Tatsutoshi Nakahata; Atsushi Miyajima
Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7265-70.
1999: A Kamiya; Taroh Kinoshita; Y Ito; T Matsui; Y Morikawa; E Senba; K Nakashima; T Taga; K Yoshida; T Kishimoto; Atsushi Miyajima
Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer.
The EMBO journal 1999;18(8):2127-36.
1999: Atsushi Miyajima; Y Ito; Taroh Kinoshita
Cytokine signaling for proliferation, survival, and death in hematopoietic cells.
International journal of hematology 1999;69(3):137-46.
1999: D Chida; O Miura; A Yoshimura; Atsushi Miyajima
Role of cytokine signaling molecules in erythroid differentiation of mouse fetal liver hematopoietic cells: functional analysis of signaling molecules by retrovirus-mediated expression.
Blood 1999;93(5):1567-78.
1999: Minoru Tanaka; Takahiko Hara; Neal G Copeland; D J Gilbert; N A Jenkins; Atsushi Miyajima
Reconstitution of the functional mouse oncostatin M (OSM) receptor: molecular cloning of the mouse OSM receptor beta subunit.
Blood 1999;93(3):804-15.
1998: D Chida; H Wakao; A Yoshimura; Atsushi Miyajima
Transcriptional regulation of the beta-casein gene by cytokines: cross-talk between STAT5 and other signaling molecules.
Molecular endocrinology (Baltimore, Md.) 1998;12(11):1792-806.
1998: Takahiko Hara; K Tamura; M P de Miguel; Yoh-suke Mukouyama; H j Kim; H Kogo; Peter J Donovan; Atsushi Miyajima
Distinct roles of oncostatin M and leukemia inhibitory factor in the development of primordial germ cells and sertoli cells in mice.
Developmental biology 1998;201(2):144-53.
1998: Ming-Jiang Xu; Kunikazu Tsuji; Takahiro Ueda; Y S Mukouyama; T Hara; FC Yang; Yasuhiro Ebihara; S Matsuoka; Atsushi Manabe; Akira Kikuchi; Mamoru Ito; Atsushi Miyajima; Tatsutoshi Nakahata
Stimulation of mouse and human primitive hematopoiesis by murine embryonic aorta-gonad-mesonephros-derived stromal cell lines.
Blood 1998;92(6):2032-40.
1998: Minoru Tanaka; Atsushi Miyajima
[Classification of cytokine receptor superfamily and signal transduction--structural feature and functional property].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(7):1784-90.
1998: Y Morikawa; H Nishida; K Misawa; T Nosaka; Atsushi Miyajima; E Senba; T Kitamura
Induction of synaptosomal-associated protein-23 kD (SNAP-23) by various cytokines.
Blood 1998;92(1):129-35.
1998: T Yamashita; H Wakao; Atsushi Miyajima; Shigetaka Asano
Differentiation inducers modulate cytokine signaling pathways in a murine erythroleukemia cell line.
Cancer research 1998;58(3):556-61.
1998: Yoh-suke Mukouyama; Takahiko Hara; M Xu; K Tamura; Peter J Donovan; H Kim; H Kogo; Kunikazu Tsuji; Tatsutoshi Nakahata; Atsushi Miyajima
In vitro expansion of murine multipotential hematopoietic progenitors from the embryonic aorta-gonad-mesonephros region.
Immunity 1998;8(1):105-14.
1997: T Ohta; Taroh Kinoshita; Makoto Naito; T Nozaki; M Masutani; Takashi Tsuruo; Atsushi Miyajima
Requirement of the caspase-3/CPP32 protease cascade for apoptotic death following cytokine deprivation in hematopoietic cells.
The Journal of biological chemistry 1997;272(37):23111-6.
1997: Taroh Kinoshita; Mikako Shirouzu; Akira Kamiya; K Hashimoto; Shigeyuki Yokoyama; Atsushi Miyajima
Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells.
Oncogene 1997;15(6):619-27.
1997: D Chida; Atsushi Miyajima
[Cytokine signaling].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(10 Suppl):1525-31.
1997: H Chin; H Wakao; Atsushi Miyajima; Ryuichi Kamiyama; Nobuyuki Miyasaka; Osamu Miura
Erythropoietin induces tyrosine phosphorylation of the interleukin-3 receptor beta subunit (betaIL3) and recruitment of Stat5 to possible Stat5-docking sites in betaIL3.
Blood 1997;89(12):4327-36.
1997: Atsushi Miyajima
[Recent progress in cytokine signal transduction].
Arerugī = [Allergy] 1997;46(6):483-8.
1997: H Wakao; D Chida; Jacqueline E Damen; Gerald Krystal; Atsushi Miyajima
A possible involvement of Stat5 in erythropoietin-induced hemoglobin synthesis.
Biochemical and biophysical research communications 1997;234(1):198-205.
1997: N Yamashita; S Y Kazuo; M Kitamura; H Wakao; Kazuo Furihata; K Furihata; Yoichi Hayakawa; Atsushi Miyajima; Haruo Seto
Cytovaricin B, a new inhibitor of JAK-STAT signal transduction produced by Streptomyces torulosus.
The Journal of antibiotics 1997;50(5):440-2.
1997: Takahiko Hara; M Ichihara; A Yoshimura; Atsushi Miyajima
Cloning and biological activity of murine oncostatin M.
Leukemia 1997;11 Suppl 3():449-50.
1997: Jacqueline E Damen; L Liu; H Wakao; Atsushi Miyajima; Patricia M Rosten; A B Jefferson; Philip W Majerus; Jana Krosl; R Keith Humphries; Gerald Krystal
The role of erythropoietin receptor tyrosine phosphorylation in erythropoietin-induced proliferation.
Leukemia 1997;11 Suppl 3():423-5.
1997: Atsushi Miyajima; Taroh Kinoshita; H Wakao; Takahiko Hara; A Yoshimura; R Nishinakamura; R Murray; A Mui
Signal transduction by the GM-CSF, IL-3 and IL-5 receptors.
Leukemia 1997;11 Suppl 3():418-22.
1997: Atsushi Miyajima
Cytokine regulation: an overview.
Leukemia 1997;11 Suppl 3():413-5.
1996: Takahiko Hara; Atsushi Miyajima
Function and signal transduction mediated by the interleukin 3 receptor system in hematopoiesis.
Stem cells (Dayton, Ohio) 1996;14(6):605-18.
1996: Y Morikawa; K Tohya; T Hara; T Kitamura; Atsushi Miyajima
Expression of IL-3 receptor in testis.
Biochemical and biophysical research communications 1996;226(1):107-12.
1996: M Onishi; A L Mui; Y Morikawa; L Cho; S Kinoshita; G P Nolan; D M Gorman; Atsushi Miyajima; T Kitamura
Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer.
Blood 1996;88(4):1399-406.
1996: A L Mui; H Wakao; T Kinoshita; T Kitamura; Atsushi Miyajima
Suppression of interleukin-3-induced gene expression by a C-terminal truncated Stat5: role of Stat5 in proliferation.
The EMBO journal 1996;15(10):2425-33.
1996: A M O'Farrell; M Ichihara; A L Mui; Atsushi Miyajima
Signaling pathways activated in a unique mast cell line where interleukin-3 supports survival and stem cell factor is required for a proliferative response.
Blood 1996;87(9):3655-68.
1996: A Muto; S Watanabe; Atsushi Miyajima; Takanori Yokota; K i Arai
The beta subunit of human granulocyte-macrophage colony-stimulating factor receptor forms a homodimer and is activated via association with the alpha subunit.
The Journal of experimental medicine 1996;183(4):1911-6.
1996: Takashi Itoh; A Muto; S Watanabe; Atsushi Miyajima; Takanori Yokota; K i Arai
Granulocyte-macrophage colony-stimulating factor provokes RAS activation and transcription of c-fos through different modes of signaling.
The Journal of biological chemistry 1996;271(13):7587-92.
1996: M Onishi; S Kinoshita; Y Morikawa; A Shibuya; J Phillips; Lewis L Lanier; D M Gorman; G P Nolan; Atsushi Miyajima; T Kitamura
Applications of retrovirus-mediated expression cloning.
Experimental hematology 1996;24(2):324-9.
1995: A Muto; S Watanabe; Takashi Itoh; Atsushi Miyajima; Takanori Yokota; K i Arai
Roles of the cytoplasmic domains of the alpha and beta subunits of human granulocyte-macrophage colony-stimulating factor receptor.
The Journal of allergy and clinical immunology 1995;96(6 Pt 2):1100-14.
1995: T Hara; K B Bacon; L C Cho; A Yoshimura; Y Morikawa; N G Copeland; D J Gilbert; N A Jenkins; T J Schall; Atsushi Miyajima
Molecular cloning and functional characterization of a novel member of the C-C chemokine family.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(11):5352-8.
1995: Jacqueline E Damen; H Wakao; Atsushi Miyajima; Jana Krosl; R Keith Humphries; R L Cutler; Gerald Krystal
Tyrosine 343 in the erythropoietin receptor positively regulates erythropoietin-induced cell proliferation and Stat5 activation.
The EMBO journal 1995;14(22):5557-68.
1995: T Kitamura; M Onishi; S Kinoshita; A Shibuya; Atsushi Miyajima; G P Nolan
Efficient screening of retroviral cDNA expression libraries.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9146-50.
1995: A S Ho; S H Wei; A L Mui; Atsushi Miyajima; Kevin W Moore
Functional regions of the mouse interleukin-10 receptor cytoplasmic domain.
Molecular and cellular biology 1995;15(9):5043-53.
1995: T Kinoshita; T Yokota; K i Arai; Atsushi Miyajima
Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells.
Oncogene 1995;10(11):2207-12.
1995: H Wakao; N Harada; T Kitamura; A L Mui; Atsushi Miyajima
Interleukin 2 and erythropoietin activate STAT5/MGF via distinct pathways.
The EMBO journal 1995;14(11):2527-35.
1995: T Hara; M Ichihara; M Takagi; Atsushi Miyajima
Interleukin-3 (IL-3) poor-responsive inbred mouse strains carry the identical deletion of a branch point in the IL-3 receptor alpha subunit gene.
Blood 1995;85(9):2331-6.
1995: Ichiko Nishijima; Tatsutoshi Nakahata; Y Hirabayashi; T Inoue; H Kurata; Atsushi Miyajima; N Hayashi; Y Iwakura; K i Arai; Takanori Yokota
A human GM-CSF receptor expressed in transgenic mice stimulates proliferation and differentiation of hemopoietic progenitors to all lineages in response to human GM-CSF.
Molecular biology of the cell 1995;6(5):497-508.
1995: A L Mui; H Wakao; N Harada; A M O'Farrell; Atsushi Miyajima
Interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 transduce signals through two forms of STAT5.
Journal of leukocyte biology 1995;57(5):799-803.
1995: S Watanabe; Yoshiaki Ito; Atsushi Miyajima; K i Arai
Granulocyte macrophage-colony stimulating factor-dependent replication of polyoma virus replicon in hematopoietic cells. Analyses of receptor signals for replication and transcription.
The Journal of biological chemistry 1995;270(16):9615-21.
1995: A L Mui; H Wakao; A M O'Farrell; N Harada; Atsushi Miyajima
Interleukin-3, granulocyte-macrophage colony stimulating factor and interleukin-5 transduce signals through two STAT5 homologs.
The EMBO journal 1995;14(6):1166-75.
1995: H Kosugi; Y Nakagawa; T Hotta; H Saito; Atsushi Miyajima; K i Arai; Takanori Yokota
Structure of the gene encoding the alpha subunit of the human interleukin 3 receptor.
Biochemical and biophysical research communications 1995;208(1):360-7.
1995: A Muto; S Watanabe; Atsushi Miyajima; Takanori Yokota; K i Arai
High affinity chimeric human granulocyte-macrophage colony-stimulating factor receptor carrying the cytoplasmic domain of the beta subunit but not the alpha subunit transduces growth promoting signals in Ba/F3 cells.
Biochemical and biophysical research communications 1995;208(1):368-75.
1995: M Ichihara; T Hara; M Takagi; L C Cho; D M Gorman; Atsushi Miyajima
Impaired interleukin-3 (IL-3) response of the A/J mouse is caused by a branch point deletion in the IL-3 receptor alpha subunit gene.
The EMBO journal 1995;14(5):939-50.
1995: M Takagi; T Hara; M Ichihara; K Takatsu; Atsushi Miyajima
Multi-colony stimulating activity of interleukin 5 (IL-5) on hematopoietic progenitors from transgenic mice that express IL-5 receptor alpha subunit constitutively.
The Journal of experimental medicine 1995;181(3):889-99.
1995: I Miyajima; L Levitt; T Hara; M A Bedell; N G Copeland; N A Jenkins; Atsushi Miyajima
The murine interleukin-3 receptor alpha subunit gene: chromosomal localization, genomic structure, and promoter function.
Blood 1995;85(5):1246-53.
1995: Kunikazu Tsuji; K Koike; A Komiyama; Atsushi Miyajima; K i Arai; Tatsutoshi Nakahata
Synergistic action of interleukin-10 (IL-10) with IL-3, IL-4 and stem cell factor on colony formation from murine mast cells in culture.
International journal of hematology 1995;61(2):51-60.
1995: T Kinoshita; T Yokota; K i Arai; Atsushi Miyajima
Suppression of apoptotic death in hematopoietic cells by signalling through the IL-3/GM-CSF receptors.
The EMBO journal 1995;14(2):266-75.
1994: T Hara; Atsushi Miyajima
Regulation of IL-3 receptor expression: evidence for a post-transcriptional mechanism that dominantly suppresses the expression of beta subunits.
International immunology 1994;6(10):1525-33.
1994: J X Chen; S Watanabe; A Muto; Atsushi Miyajima; Takanori Yokota; K i Arai
Activation of early response genes and cell proliferation by human interleukin-3, granulocyte-macrophage colony-stimulating factor, and interleukin-5 receptors: comparison with human interleukin-4 receptor signaling.
The Journal of allergy and clinical immunology 1994;94(3 Pt 2):605-11.
1994: T Hara; N Harada; H Mitsui; T Miura; TERUKO ISHIZAKA; Atsushi Miyajima
Characterization of cell phenotype by a novel cDNA library subtraction system: expression of CD8 alpha in a mast cell-derived interleukin-4-dependent cell line.
Blood 1994;84(1):189-99.
1994: Y Nakagawa; H Kosugi; Atsushi Miyajima; K i Arai; Takanori Yokota
Structure of the gene encoding the alpha subunit of the human granulocyte-macrophage colony stimulating factor receptor. Implications for the evolution of the cytokine receptor superfamily.
The Journal of biological chemistry 1994;269(14):10905-12.
1994: N Sato; Atsushi Miyajima
Multimeric cytokine receptors: common versus specific functions.
Current opinion in cell biology 1994;6(2):174-9.
1994: A Mui; A Muto; K Sakamaki; N Sato; T Kinoshita; S Watanabe; T Yokota; K i Arai; Atsushi Miyajima
Function of the common beta subunit of the GM-CSF/IL-3/IL-5 receptors.
Advances in experimental medicine and biology 1994;365():217-23.
1993: T Chiba; Y Nagata; A Kishi; K Sakamaki; Atsushi Miyajima; M Yamamoto; James Douglas Engel; Kazuo Todokoro
Induction of erythroid-specific gene expression in lymphoid cells.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11593-7.
1993: N Sato; K Sakamaki; N Terada; K i Arai; Atsushi Miyajima
Signal transduction by the high-affinity GM-CSF receptor: two distinct cytoplasmic regions of the common beta subunit responsible for different signaling.
The EMBO journal 1993;12(11):4181-9.
1993: Atsushi Miyajima; A L Mui; T Ogorochi; K Sakamaki
Receptors for granulocyte-macrophage colony-stimulating factor, interleukin-3, and interleukin-5.
Blood 1993;82(7):1960-74.
1993: K Izuhara; G Yang; Atsushi Miyajima; M Howard; N Harada
Structure of the IL4 receptor and signal transduction mechanism of IL4.
Research in immunology 1993;144(8):584-90.
1993: S Watanabe; A Muto; Takanori Yokota; Atsushi Miyajima; K i Arai
Differential regulation of early response genes and cell proliferation through the human granulocyte macrophage colony-stimulating factor receptor: selective activation of the c-fos promoter by genistein.
Molecular biology of the cell 1993;4(10):983-92.
1993: Takanori Yokota; S Watanabe; A L Mui; A Muto; Atsushi Miyajima; K i Arai
Reconstitution of functional human GM-CSF receptor in mouse NIH3T3 fibroblasts and BA/F3 proB cells.
Leukemia 1993;7 Suppl 2():S102-7.
1993: N Sato; Christophe Caux; T Kitamura; Y Watanabe; K i Arai; Jacques Banchereau; Atsushi Miyajima
Expression and factor-dependent modulation of the interleukin-3 receptor subunits on human hematopoietic cells.
Blood 1993;82(3):752-61.
1993: K Sakamaki; H M Wang; I Miyajima; T Kitamura; Kazuo Todokoro; N Harada; Atsushi Miyajima
Ligand-dependent activation of chimeric receptors with the cytoplasmic domain of the interleukin-3 receptor beta subunit (beta IL3).
The Journal of biological chemistry 1993;268(21):15833-9.
1993: S Takaki; Y Murata; T Kitamura; Atsushi Miyajima; A Tominaga; Kiyoshi Takatsu
Reconstitution of the functional receptors for murine and human interleukin 5.
The Journal of experimental medicine 1993;177(6):1523-9.
1993: Y Hanazono; Shigeru Chiba; Kazuki Sasaki; H Mano; Atsushi Miyajima; K i Arai; Y Yazaki; H Hirai
c-fps/fes protein-tyrosine kinase is implicated in a signaling pathway triggered by granulocyte-macrophage colony-stimulating factor and interleukin-3.
The EMBO journal 1993;12(4):1641-6.
1993: S Watanabe; A L Mui; A Muto; J X Chen; K Hayashida; Takanori Yokota; Atsushi Miyajima; K i Arai
Reconstituted human granulocyte-macrophage colony-stimulating factor receptor transduces growth-promoting signals in mouse NIH 3T3 cells: comparison with signalling in BA/F3 pro-B cells.
Molecular and cellular biology 1993;13(3):1440-8.
1993: K Izuhara; Atsushi Miyajima; N Harada
The chimeric receptor between interleukin-2 receptor beta chain and interleukin-4 receptor transduces interleukin-2 signal.
Biochemical and biophysical research communications 1993;190(3):992-1000.
1992: N Harada; G Yang; Atsushi Miyajima; M Howard
Identification of an essential region for growth signal transduction in the cytoplasmic domain of the human interleukin-4 receptor.
The Journal of biological chemistry 1992;267(32):22752-8.
1992: Y Watanabe; T Kitamura; K Hayashida; Atsushi Miyajima
Monoclonal antibody against the common beta subunit (beta c) of the human interleukin-3 (IL-3), IL-5, and granulocyte-macrophage colony-stimulating factor receptors shows upregulation of beta c by IL-1 and tumor necrosis factor-alpha.
Blood 1992;80(9):2215-20.
1992: K i Arai; S Watanabe; N Koyano; H J Lee; Atsushi Miyajima; H Yssel; Naoko Arai; Takanori Yokota
Cytokine network: control of allergic response and hemopoiesis by hemopoietic growth factors.
The Journal of dermatology 1992;19(10):575-83.
1992: Atsushi Miyajima; T Hara; T Kitamura
Common subunits of cytokine receptors and the functional redundancy of cytokines.
Trends in biochemical sciences 1992;17(10):378-82.
1992: K Sakamaki; I Miyajima; T Kitamura; Atsushi Miyajima
Critical cytoplasmic domains of the common beta subunit of the human GM-CSF, IL-3 and IL-5 receptors for growth signal transduction and tyrosine phosphorylation.
The EMBO journal 1992;11(10):3541-9.
1992: D M Gorman; N Itoh; N A Jenkins; D J Gilbert; N G Copeland; Atsushi Miyajima
Chromosomal localization and organization of the murine genes encoding the beta subunits (AIC2A and AIC2B) of the interleukin 3, granulocyte/macrophage colony-stimulating factor, and interleukin 5 receptors.
The Journal of biological chemistry 1992;267(22):15842-8.
1992: T Kitamura; Atsushi Miyajima
Functional reconstitution of the human interleukin-3 receptor.
Blood 1992;80(1):84-90.
1992: J L Imler; Atsushi Miyajima; Gerard Zurawski
Identification of three adjacent amino acids of interleukin-2 receptor beta chain which control the affinity and the specificity of the interaction with interleukin-2.
The EMBO journal 1992;11(6):2047-53.
1992: Atsushi Miyajima
Molecular structure of the IL-3, GM-CSF and IL-5 receptors.
International journal of cell cloning 1992;10(3):126-34.
1992: T Hara; Atsushi Miyajima
Two distinct functional high affinity receptors for mouse interleukin-3 (IL-3).
The EMBO journal 1992;11(5):1875-84.
1992: G X Xie; Atsushi Miyajima; A Goldstein
Expression cloning of cDNA encoding a seven-helix receptor from human placenta with affinity for opioid ligands.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(9):4124-8.
1992: T Ogorochi; T Hara; H M Wang; K Maruyama; Atsushi Miyajima
Monoclonal antibodies specific for low-affinity interleukin-3 (IL-3) binding protein AIC2A: evidence that AIC2A is a component of a high-affinity IL-3 receptor.
Blood 1992;79(4):895-903.
1992: H M Wang; T Ogorochi; K i Arai; Atsushi Miyajima
Structure of mouse interleukin 3 (IL-3) binding protein (AIC2A). Amino acid residues critical for IL-3 binding.
The Journal of biological chemistry 1992;267(2):979-83.
1992: N Wrighton; L A Campbell; N Harada; Atsushi Miyajima; F Lee
The murine interleukin-4 receptor gene: genomic structure, expression and potential for alternative splicing.
Growth factors (Chur, Switzerland) 1992;6(2):103-18.
1992: J Schreurs; D M Gorman; Atsushi Miyajima
Cytokine receptors: a new superfamily of receptors.
International review of cytology 1992;137B():121-55.
1991: A B Shanafelt; Atsushi Miyajima; T Kitamura; Robert A Kastelein
The amino-terminal helix of GM-CSF and IL-5 governs high affinity binding to their receptors.
The EMBO journal 1991;10(13):4105-12.
1991: J Schreurs; P Hung; W S May; K i Arai; Atsushi Miyajima
AIC2A is a component of the purified high affinity mouse IL-3 receptor: temperature-dependent modulation of AIC2A structure.
International immunology 1991;3(12):1231-42.
1991: T Kitamura; N Sato; K i Arai; Atsushi Miyajima
Expression cloning of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors.
Cell 1991;66(6):1165-74.
1991: T Eki; T Enomoto; C Masutani; Atsushi Miyajima; R Takada; Y Murakami; T Ohno; F Hanaoka; M Ui
Mouse DNA primase plays the principal role in determination of permissiveness for polyomavirus DNA replication.
Journal of virology 1991;65(9):4874-81.
1991: H Ishida; G Yang; N Harada; R L Hastings; B E Castle; Robert A Kastelein; Atsushi Miyajima; M Howard
Evaluation of murine interleukin 4 (IL-4) receptor expression using anti-receptor monoclonal antibodies and S1 nuclease protection analyses.
Cellular immunology 1991;136(1):142-54.
1991: T Kitamura; K Hayashida; K Sakamaki; T Yokota; K i Arai; Atsushi Miyajima
Reconstitution of functional receptors for human granulocyte/macrophage colony-stimulating factor (GM-CSF): evidence that the protein encoded by the AIC2B cDNA is a subunit of the murine GM-CSF receptor.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5082-6.
1991: T Kitamura; F Takaku; Atsushi Miyajima
IL-1 up-regulates the expression of cytokine receptors on a factor-dependent human hemopoietic cell line, TF-1.
International immunology 1991;3(6):571-7.
1991: J Nishida; T Yokota; Atsushi Miyajima
[IL-3: production mechanism and the receptor].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1159-67.
1991: S Watanabe; N Nakayama; Takanori Yokota; K i Arai; Atsushi Miyajima
[Hemopoietic growth factors and signal transduction].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1114-23.
1991: T Satoh; M Nakafuku; Atsushi Miyajima; Y Kaziro
Involvement of ras p21 protein in signal-transduction pathways from interleukin 2, interleukin 3, and granulocyte/macrophage colony-stimulating factor, but not from interleukin 4.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3314-8.
1991: S Watanabe; N Nakayama; Takanori Yokota; K i Arai; Atsushi Miyajima
Colony-stimulating factors and cytokine receptor network.
Current opinion in biotechnology 1991;2(2):227-37.
1990: K Hayashida; T Kitamura; D M Gorman; K i Arai; T Yokota; Atsushi Miyajima
Molecular cloning of a second subunit of the receptor for human granulocyte-macrophage colony-stimulating factor (GM-CSF): reconstitution of a high-affinity GM-CSF receptor.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9655-9.
1990: D M Gorman; N Itoh; T Kitamura; J Schreurs; S Yonehara; I Yahara; K i Arai; Atsushi Miyajima
Cloning and expression of a gene encoding an interleukin 3 receptor-like protein: identification of another member of the cytokine receptor gene family.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5459-63.
1990: K i Arai; J Nishida; K Hayashida; K Hatake; T Kitamura; Atsushi Miyajima; N Arai; T Yokota
[Coordinate regulation of immune and inflammatory responses by cytokines].
Rinsho byori. The Japanese journal of clinical pathology 1990;38(4):347-53.
1990: G X Xie; Atsushi Miyajima; T Yokota; K i Arai; A Goldstein
Chimeric opioid peptides: tools for identifying opioid receptor types.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3180-4.
1990: N Harada; B E Castle; D M Gorman; N Itoh; J Schreurs; R L Barrett; M Howard; Atsushi Miyajima
Expression cloning of a cDNA encoding the murine interleukin 4 receptor based on ligand binding.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(3):857-61.
1990: M Seki; T Enomoto; T Eki; Atsushi Miyajima; Y Murakami; F Hanaoka; M Ui
DNA helicase and nucleoside-5'-triphosphatase activities of polyoma virus large tumor antigen.
Biochemistry 1990;29(4):1003-9.
1990: N Itoh; S Yonehara; J Schreurs; D M Gorman; K Maruyama; A Ishii; I Yahara; K i Arai; Atsushi Miyajima
Cloning of an interleukin-3 receptor gene: a member of a distinct receptor gene family.
Science (New York, N.Y.) 1990;247(4940):324-7.
1990: T Eki; T Enomoto; Atsushi Miyajima; H Miyazawa; Y Murakami; F Hanaoka; M Yamada; M Ui
Isolation of temperature-sensitive cell cycle mutants from mouse FM3A cells. Characterization of mutants with special reference to DNA replication.
The Journal of biological chemistry 1990;265(1):26-33.
1990: J Schreurs; K i Arai; Atsushi Miyajima
Evidence for a low-affinity interleukin-3 receptor.
Growth factors (Chur, Switzerland) 1990;2(2-3):221-33.
1989: H M Wang; M Collins; K i Arai; Atsushi Miyajima
EGF induces differentiation of an IL-3-dependent cell line expressing the EGF receptor.
The EMBO journal 1989;8(12):3677-84.
1989: N Nakayama; K Hatake; Atsushi Miyajima; K i Arai; T Yokota
Colony-stimulating factors, cytokines and hematopoiesis.
Current opinion in immunology 1989;2(1):68-77.
1989: J Schreurs; M Sugawara; K i Arai; Y Ohta; Atsushi Miyajima
A monoclonal antibody with IL-3-like activity blocks IL-3 binding and stimulates tyrosine phosphorylation.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):819-25.
1988: Atsushi Miyajima; S Miyatake; J Schreurs; J De Vries; Naoko Arai; T Yokota; K i Arai
Coordinate regulation of immune and inflammatory responses by T cell-derived lymphokines.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1988;2(9):2462-73.
1988: T Otsuka; Atsushi Miyajima; N Brown; K Otsu; J Abrams; Sem Saeland; Christophe Caux; R de Waal Malefijt; J de Vries; P Meyerson
Isolation and characterization of an expressible cDNA encoding human IL-3. Induction of IL-3 mRNA in human T cell clones.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(7):2288-95.
1988: Masato Nakafuku; Tomoko Obara; K Kaibuchi; I Miyajima; Atsushi Miyajima; H Itoh; S Nakamura; K i Arai; K Matsumoto; Y Kaziro
Isolation of a second yeast Saccharomyces cerevisiae gene (GPA2) coding for guanine nucleotide-binding regulatory protein: studies on its structure and possible functions.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(5):1374-8.
1988: K Matsumoto; Masato Nakafuku; N Nakayama; I Miyajima; K Kaibuchi; Atsushi Miyajima; C Brenner; K i Arai; Y Kaziro
The role of G proteins in yeast signal transduction.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():567-75.
1987: I Miyajima; Masato Nakafuku; N Nakayama; C Brenner; Atsushi Miyajima; K Kaibuchi; K i Arai; Y Kaziro; K Matsumoto
GPA1, a haploid-specific essential gene, encodes a yeast homolog of mammalian G protein which may be involved in mating factor signal transduction.
Cell 1987;50(7):1011-9.
1987: N Nakayama; Atsushi Miyajima; K i Arai
Common signal transduction system shared by STE2 and STE3 in haploid cells of Saccharomyces cerevisiae: autocrine cell-cycle arrest results from forced expression of STE2.
The EMBO journal 1987;6(1):249-54.
1987: Atsushi Miyajima; J Schreurs; K Otsu; A Kondo; K i Arai; S Maeda
Use of the silkworm, Bombyx mori, and an insect baculovirus vector for high-level expression and secretion of biologically active mouse interleukin-3.
Gene 1987;58(2-3):273-81.
1986: Atsushi Miyajima; K Otsu; J Schreurs; M W Bond; J S Abrams; K i Arai
Expression of murine and human granulocyte-macrophage colony-stimulating factors in S. cerevisiae: mutagenesis of the potential glycosylation sites.
The EMBO journal 1986;5(6):1193-7.
1985: N Nakayama; Atsushi Miyajima; K i Arai
Nucleotide sequences of STE2 and STE3, cell type-specific sterile genes from Saccharomyces cerevisiae.
The EMBO journal 1985;4(10):2643-8.
1985: Atsushi Miyajima; M W Bond; K Otsu; K i Arai; N Arai
Secretion of mature mouse interleukin-2 by Saccharomyces cerevisiae: use of a general secretion vector containing promoter and leader sequences of the mating pheromone alpha-factor.
Gene 1985;37(1-3):155-61.