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Takeshi Miyamoto

Research Profile

Anatomy

Physiology

Procedures

Chemicals & Drugs

Living Beings

Devices

Intraocular Lenses

Disorders

Cataract

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Publications

TOP 3
Shizuya Saika; Kumi Shirai; Takayoshi Sumioka; Osamu Yamanaka; Ai Kitano; Takeshi Miyamoto; Yuka Okada; Hideaki Kokado
Wakayama symposium: modulation of wound healing response in the corneal stroma by osteopontin and tenascin-C.
Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses part 2: experimental study of a surface-modified IOL in rabbits.
Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses: part 1: analysis of explanted IOLs.

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All Publications

2013: Shizuya Saika; Kumi Shirai; Takayoshi Sumioka; Osamu Yamanaka; Ai Kitano; Takeshi Miyamoto; Yuka Okada; Hideaki Kokado
Wakayama symposium: modulation of wound healing response in the corneal stroma by osteopontin and tenascin-C.
The ocular surface 2013;11(1):12-5.
2011: Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses part 2: experimental study of a surface-modified IOL in rabbits.
Journal of cataract and refractive surgery 2011;37(7):1339-42.
2011: Nobuyuki Ishikawa; Takeshi Miyamoto; Yuka Okada; Shizuya Saika
Cell adhesion on explanted intraocular lenses: part 1: analysis of explanted IOLs.
Journal of cataract and refractive surgery 2011;37(7):1333-8.
2010: Shizuya Saika; Osamu Yamanaka; Takayoshi Sumioka; Yuka Okada; Takeshi Miyamoto; Kumi Shirai; Ai Kitano; Sai-ichi Tanaka
Transforming growth factor beta signal transduction: a potential target for maintenance/restoration of transparency of the cornea.
Eye & contact lens 2010;36(5):286-9.
2010: Norihito Fujita; Shuko Fujita; Yuka Okada; Kyoko Fujita; Ai Kitano; Osamu Yamanaka; Takeshi Miyamoto; Shigeyuki Kon; Toshimitsu Uede; Susan R Rittling; David T Denhardt; Shizuya Saika
Impaired angiogenic response in the corneas of mice lacking osteopontin.
Investigative ophthalmology & visual science 2010;51(2):790-4.
2009: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Takeshi Miyamoto; Takayoshi Sumioka; Ai Kitano; Kumi Shirai; Kazuo Ikeda
TGF beta in fibroproliferative diseases in the eye.
Frontiers in bioscience (Scholar edition) 2009;1():376-90.
2009: Kyoko Fujita; Takeshi Miyamoto; Shizuya Saika
Sonic hedgehog: its expression in a healing cornea and its role in neovascularization.
Molecular vision 2009;15():1036-44.
2008: Kyoko Fujita; Takeshi Miyamoto; Yuka Okada; Nobuyuki Ishikawa; Shizuya Saika
Expression pattern of sonic hedgehog and effect of topical mitomycin C on its expression in human ocular surface neoplasms.
Japanese journal of ophthalmology 2008;52(3):190-4.
2008: Shizuya Saika; Osamu Yamanaka; Kathleen C Flanders; Yuka Okada; Takeshi Miyamoto; Takayoshi Sumioka; Kumi Shirai; Ai Kitano; Ken-ichi Miyazaki; Sai-ichi Tanaka; Kazuo Ikeda
Epithelial-mesenchymal transition as a therapeutic target for prevention of ocular tissue fibrosis.
Endocrine, metabolic & immune disorders drug targets 2008;8(1):69-76.
2008: Shizuya Saika; Osamu Yamanaka; Takayoshi Sumioka; Takeshi Miyamoto; Ken-ichi Miyazaki; Yuka Okada; Ai Kitano; Kumi Shirai; Sai-ichi Tanaka; Kazuo Ikeda
Fibrotic disorders in the eye: targets of gene therapy.
Progress in retinal and eye research 2008;27(2):177-96.
2007: Shizuya Saika; Osamu Yamanaka; Yuka Okada; Takeshi Miyamoto; Ai Kitano; Kathleen C Flanders; Yoshitaka Ohnishi; Yuji Nakajima; Winston W-Y Kao; Kazuo Ikeda
Effect of overexpression of PPARgamma on the healing process of corneal alkali burn in mice.
American journal of physiology. Cell physiology 2007;293(1):C75-86.
2007: Shuko Fujita; Shizuya Saika; Winston W-Y Kao; Kyoko Fujita; Takeshi Miyamoto; Kazuo Ikeda; Yuji Nakajima; Yoshitaka Ohnishi
Endogenous TNFalpha suppression of neovascularization in corneal stroma in mice.
Investigative ophthalmology & visual science 2007;48(7):3051-5.
2007: Yuka Okada; Kazuo Ikeda; Osamu Yamanaka; Takeshi Miyamoto; Ai Kitano; Winston W-Y Kao; Shizuya Saika
TNFalpha suppression of corneal epithelium migration.
Molecular vision 2007;13():1428-35.
2007: Yuka Okada; Shizuya Saika; Takeshi Miyamoto; Kumi Shirai; Takashi Ueyama; Emiko Senba; Yoshitaka Ohnishi
AP-1 expression in ethanol-treated corneal epithelium in vivo.
Ophthalmic research 2007;39(2):84-91.
2006: Takeshi Miyamoto; Shizuya Saika; Takashi Ueyama; Yuka Okada; Kumi Shirai; Takayoshi Sumioka; Kyoko Fujita; Nobuyuki Ishiwaka; Yoshitaka Ohnishi
Cyclooxygenase 2 expression in rat corneas after ethanol exposure.
Journal of cataract and refractive surgery 2006;32(10):1736-40.
2006: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuka Okada; Takeshi Miyamoto; Ai Kitano; Akira Ooshima; Yuji Nakajima; Yoshitaka Ohnishi; Winston W-Y Kao
Loss of tumor necrosis factor alpha potentiates transforming growth factor beta-mediated pathogenic tissue response during wound healing.
The American journal of pathology 2006;168(6):1848-60.
2005: Yoshitaka Ohnishi; Shizuya Saika; Osamu Yamanaka; Yuka Okada; Kumi Shirai; Takeshi Miyamoto; Iku Nishikawa; Takeshi Tanaka; Kenichi Miyazaki
[Investigation of mechanism of cell proliferation regulation and its clinical application].
Nippon Ganka Gakkai zasshi 2005;109(12):865-83; discussion 884.
2005: Walid Khaled Barbour; Shizuya Saika; Takeshi Miyamoto; Yoshitaka Ohnishi
Biological compatibility of polymethyl methacrylate, hydrophilic acrylic and hydrophobic acrylic intraocular lenses.
Ophthalmic research 2005;37(5):255-61.
2005: Kumi Shirai; Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Takashi Ueyama; Yoshitaka Ohnishi
Transcriptional activation in lens epithelial cells following an ocular blunt trauma.
Journal of cataract and refractive surgery 2005;31(6):1226-30.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Takeshi Miyamoto; Yoshitaka Ohnishi; Misako Sato; Yasuteru Muragaki; Akira Ooshima; Yuji Nakajima; Winston W-Y Kao; Kathleen C Flanders; Anita B Roberts
Expression of Smad7 in mouse eyes accelerates healing of corneal tissue after exposure to alkali.
The American journal of pathology 2005;166(5):1405-18.
2005: Shizuya Saika; Takeshi Miyamoto; Osamu Yamanaka; Tadashi Kato; Yoshitaka Ohnishi; Kathleen C Flanders; Kazuo Ikeda; Yuji Nakajima; Winston W-Y Kao; Misako Sato; Yasuteru Muragaki; Akira Ooshima
Therapeutic effect of topical administration of SN50, an inhibitor of nuclear factor-kappaB, in treatment of corneal alkali burns in mice.
The American journal of pathology 2005;166(5):1393-403.
2005: Shizuya Saika; Kazuo Ikeda; Osamu Yamanaka; Kathleen C Flanders; Yuji Nakajima; Takeshi Miyamoto; Yoshitaka Ohnishi; Winston W-Y Kao; Yasuteru Muragaki; Akira Ooshima
Therapeutic effects of adenoviral gene transfer of bone morphogenic protein-7 on a corneal alkali injury model in mice.
Laboratory investigation; a journal of technical methods and pathology 2005;85(4):474-86.
2004: Takeshi Miyamoto; Shizuya Saika; Yuka Okada; Yoshiji Kawashima; Takayoshi Sumioka; Norihito Fujita; Yoshitaka Suzuki; Akio Yamanaka; Yoshitaka Ohnishi
Expression of cyclooxygenase-2 in corneal cells after photorefractive keratectomy and laser in situ keratomileusis in rabbits.
Journal of cataract and refractive surgery 2004;30(12):2612-7.
2004: Shizuya Saika; Yasuteru Muragaki; Yuka Okada; Takeshi Miyamoto; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Sonic hedgehog expression and role in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(8):2577-85.
2004: Walid Khaled Barbour; Shizuya Saika; Takeshi Miyamoto; Kiyomi Ohkawa; Hirotoshi Utsunomiya; Yoshitaka Ohnishi
Expression patterns of beta1-related alpha integrin subunits in murine lens during embryonic development and wound healing.
Current eye research 2004;29(1):1-10.
2004: Takeshi Miyamoto; Shizuya Saika; Akio Yamanaka; Yuka Okada; Yoshitaka Ohnishi
Deposition of silicone oil droplets in the residual anterior lens capsule after vitrectomy and lensectomy in rabbits.
The British journal of ophthalmology 2004;88(5):703-7.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akio Yamanaka; Akira Ooshima
Protein expression pattern of collagen type XV in mouse cornea.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(5):432-6.
2004: Takeshi Miyamoto; Shizuya Saika; Yuka Okada; Iku Ishida-Nishikawa; Takayoshi Sumioka; Norihito Fujita; Yoshitaka Ohnishi
Topical exposure of mitomycin C reduces opacification of the residual anterior lens capsule and lenticular regeneration after vitrectomy and lensectomy in rabbits.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2004;242(4):327-31.
2004: Shizuya Saika; Yuka Okada; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Chia-Yang Liu; Daniel Weng; Winston W-Y Kao
Role of p38 MAP kinase in regulation of cell migration and proliferation in healing corneal epithelium.
Investigative ophthalmology & visual science 2004;45(1):100-9.
2003: Shizuya Saika; Takeshi Miyamoto; Yoshitaka Ohnishi
Histology of anterior capsule opacification with a polyHEMA/HOHEXMA hydrophilic hydrogel intraocular lens compared to poly(methyl methacrylate), silicone, and acrylic lenses.
Journal of cataract and refractive surgery 2003;29(6):1198-203.
2003: Shizuya Saika; Takeshi Miyamoto; Sai-ichi Tanaka; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima; Toshiyuki Ishiwata; Goro Asano; Tai-Ichiro Chikama; Atsushi Shiraishi; Chia-Yang Liu; Candace W-C Kao; Winston W-Y Kao
Response of lens epithelial cells to injury: role of lumican in epithelial-mesenchymal transition.
Investigative ophthalmology & visual science 2003;44(5):2094-102.
2003: Yuka Okada; Shizuya Saika; Kumi Shirai; Natsuko Hashizume; Takeshi Miyamoto; Osamu Yamanaka; Yoshitaka Ohnishi; Masayasu Miyajima; Emiko Senba
AP-1 (c-Fos/c-Jun) is required for corneal epithelial spreading.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2003;241(4):327-9.
2003: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Osteopontin: a component of matrix in capsular opacification and subcapsular cataract.
Investigative ophthalmology & visual science 2003;44(4):1622-8.
2003: Takeshi Miyamoto; Shizuya Saika; Akio Yamanaka; Yoshiji Kawashima; Yoshitaka Suzuki; Yoshitaka Ohnishi
Wound healing in rabbit corneas after photorefractive keratectomy and laser in situ keratomileusis.
Journal of cataract and refractive surgery 2003;29(1):153-8.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Kumi Shirai; Yoshitaka Ohnishi; Akira Ooshima; J W McAvoy
TGFbeta-Smad signalling in postoperative human lens epithelial cells.
The British journal of ophthalmology 2002;86(12):1428-33.
2002: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell death after cataract surgery.
Journal of cataract and refractive surgery 2002;28(8):1452-6.
2002: Shizuya Saika; Yuko Hayashi; Takeshi Miyamoto; Takeshi Yoshitomi; Yoshitaka Ohnishi
Multiple retinal holes in the macular region: a case report.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2002;240(7):578-9.
2002: Sai-ichi Tanaka; Shizuya Saika; Shunsaku Ohmi; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Cellular fibronectin, but not collagens, disappears in the central posterior capsules during healing after lens extraction and IOL implantation in rabbits.
Japanese journal of ophthalmology 2002;46(2):147-52.
2002: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Wataru Kimura
Histopathology of anterior lens capsules in vitrectomized eyes with tamponade by silicone oil.
Journal of cataract and refractive surgery 2002;28(2):376-8.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Collagens XII and XIV (FACITs) in capsular opacification and in cultured lens epithelial cells.
Current eye research 2001;23(6):463-8.
2001: Shizuya Saika; Takeshi Miyamoto; Takeshi Tanaka; Iku Ishida; Yoshitaka Ohnishi; Akira Ooshima
Latent TGFbeta binding protein-1 and fibrillin-1 in human capsular opacification and in cultured lens epithelial cells.
The British journal of ophthalmology 2001;85(11):1362-6.
2001: Shizuya Saika; T Tanaka; Takeshi Miyamoto; Yoshitaka Ohnishi
Surgical posterior vitreous detachment combined with gas/air tamponade for treating macular edema associated with branch retinal vein occlusion: retinal tomography and visual outcome.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(10):729-32.
2001: Natsuko Hashizume; Shizuya Saika; Yuka Okada; Takeshi Miyamoto; K Shimizu; Yoshitaka Ohnishi
Effects of antiinflammatory drugs on migration of the rabbit corneal epithelium.
Journal of cataract and refractive surgery 2001;27(9):1499-502.
2001: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Takeshi Tanaka; Yuka Okada; Y Nagane; Kumi Shirai; Yoshitaka Ohnishi
Comparison of Scheimpflug images of posterior capsule opacification and histological findings in rabbits and humans.
Journal of cataract and refractive surgery 2001;27(7):1088-92.
2001: Shizuya Saika; Takeshi Miyamoto; Iku Ishida; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Lens epithelial cell regeneration of a capsule-like structure during postoperative healing in rabbits.
Journal of cataract and refractive surgery 2001;27(7):1076-8.
2001: Shizuya Saika; Osamu Yamanaka; Y Baba; Yoshiji Kawashima; Kumi Shirai; Takeshi Miyamoto; Yuka Okada; Yoshitaka Ohnishi; Akira Ooshima
Accumulation of latent transforming growth factor-beta binding protein-1 and TGF beta 1 in extracellular matrix of filtering bleb and of cultured human subconjunctival fibroblasts.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2001;239(3):234-41.
2000: Yoshiji Kawashima; Shizuya Saika; Takeshi Miyamoto; Osamu Yamanaka; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi
Matrix metalloproteinases and tissue inhibitors of metalloproteinases of fibrous humans lens capsules with intraocular lenses.
Current eye research 2000;21(6):962-7.
2000: Shizuya Saika; A Minamide; Takeshi Tanaka; Takeshi Miyamoto; Yuka Okada; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Expression of involucrin by ocular surface epithelia of patients with benign and malignant disorders.
Current eye research 2000;21(5):877-85.
2000: Shizuya Saika; Takeshi Miyamoto; Yoshiji Kawashima; K Jinza; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Alterations in ultrastructure and c-met expression in a case of ocular epithelial dysplasia following topical mitomycin C treatment.
Japanese journal of ophthalmology 2000;44(6):639-42.
2000: Shizuya Saika; Takeshi Miyamoto; Yuka Okada; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima
Transforming growth factor-beta isoform proteins in cell and matrix deposits on intraocular lenses.
Journal of cataract and refractive surgery 2000;26(5):709-15.
1999: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; T Katoh; K Shirai; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Winston W-Y Kao
Immunolocalization of transcription factor AP1 in human ocular surface epithelia.
Current eye research 1999;18(6):477-89.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Pathological findings in lens capsule and silicone intraocular lens extracted from eye with chronic infectious endophthalmitis.
Japanese journal of ophthalmology 1998;42(6):456-60.
1998: Shizuya Saika; Takeshi Miyamoto; Akio Yamanaka; Yoshiji Kawashima; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Shunsaku Ohmi; Yoshitaka Ohnishi; Akira Ooshima
Immunohistochemical evaluation of cellular deposits on posterior chamber intraocular lenses.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 1998;236(10):758-65.
1998: Shizuya Saika; Takeshi Miyamoto; M Kimura; Shunsaku Ohmi; K Ohkawa; Yoshiji Kawashima; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Degenerated lens epithelial cells in rabbit and human eyes after intraocular lens implantation.
Journal of cataract and refractive surgery 1998;24(10):1396-8.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunohistochemical identification of proteoglycan types in fibrotic human capsules with intraocular lens implants.
Japanese journal of ophthalmology 1998;42(5):368-72.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of hyaluronan and CD44 in quiescent and proliferating human lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1266-70.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Sai-ichi Tanaka; Yuka Okada; Osamu Yamanaka; T Katoh; Yoshitaka Ohnishi; Shunsaku Ohmi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase in rabbit lens epithelial cells.
Journal of cataract and refractive surgery 1998;24(9):1261-5.
1998: Shizuya Saika; Yoshiji Kawashima; Takeshi Miyamoto; Yuka Okada; Sai-ichi Tanaka; Shunsaku Ohmi; A Minamide; Osamu Yamanaka; Yoshitaka Ohnishi; Akira Ooshima; Akio Yamanaka
Immunolocalization of prolyl 4-hydroxylase subunits, alpha-smooth muscle actin, and extracellular matrix components in human lens capsules with lens implants.
Experimental eye research 1998;66(3):283-94.
1997: Shizuya Saika; Shunsaku Ohmi; Sai-ichi Tanaka; Takeshi Miyamoto; Yoshiji Kawashima; Yoshitaka Ohnishi; R Kanagawa; Akio Yamanaka; Akira Ooshima
Cell proliferation on the outer anterior capsule surface after extracapsular lens extraction in rabbits.
Journal of cataract and refractive surgery 1997;23(10):1528-31.