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Stephan Beck

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Bäckdahl Liselotte; Herberth Marlis; Wilson Gareth; Tate Peri; Campos Lia S; Cortese Rene; Eckhardt Florian; Beck Stephan
Gene body methylation of the dimethylarginine dimethylamino-hydrolase 2 (Ddah2) gene is an epigenetic biomarker for neural stem cell differentiation.
Dennis Megan Y; Paracchini Silvia; Scerri Thomas S; Prokunina-Olsson Ludmila; Knight Julian C; Wade-Martins Richard; Coggill Penny; Beck Stephan; Green Eric D; Monaco Anthony P
A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
Bäckdahl Liselotte; Bushell Andrew; Beck Stephan
Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation.

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All Publications

2009: Bäckdahl Liselotte; Herberth Marlis; Wilson Gareth; Tate Peri; Campos Lia S; Cortese Rene; Eckhardt Florian; Beck Stephan
Gene body methylation of the dimethylarginine dimethylamino-hydrolase 2 (Ddah2) gene is an epigenetic biomarker for neural stem cell differentiation.
Epigenetics : official journal of the DNA Methylation Society 2009;4(4):248-54.
2009: Dennis Megan Y; Paracchini Silvia; Scerri Thomas S; Prokunina-Olsson Ludmila; Knight Julian C; Wade-Martins Richard; Coggill Penny; Beck Stephan; Green Eric D; Monaco Anthony P
A common variant associated with dyslexia reduces expression of the KIAA0319 gene.
PLoS genetics 2009;5(3):e1000436.
2009: Bäckdahl Liselotte; Bushell Andrew; Beck Stephan
Inflammatory signalling as mediator of epigenetic modulation in tissue-specific chronic inflammation.
The international journal of biochemistry & cell biology 2009;41(1):176-84.
2009: Siddle Hannah V; Deakin Janine E; Coggill Penny; Hart Elizabeth; Cheng Yuanyuan; Wong Emily Sw; Harrow Jennifer; Beck Stephan; Belov Katherine
MHC-linked and un-linked class I genes in the wallaby.
BMC genomics 2009;10():310.
2008: Santos Pablo Sandro Carvalho; Füst George; Prohászka Zoltán; Volz Armin; Horton Roger; Miretti Marcos; Yu Chack-Yung; Beck Stephan; Uchanska-Ziegler Barbara; Ziegler Andreas
Association of smoking behavior with an odorant receptor allele telomeric to the human major histocompatibility complex.
Genetic testing 2008;12(4):481-6.
2008: Ottaviani Diego; Lever Elliott; Mitter Richard; Jones Tania; Forshew Tim; Christova Rossitza; Tomazou Eleni M; Rakyan Vardhman K; Krawetz Stephen A; Platts Adrian E; Segarane Badmavady; Beck Stephan; Sheer Denise
Reconfiguration of genomic anchors upon transcriptional activation of the human major histocompatibility complex.
Genome research 2008;18(11):1778-86.
2008: Rakyan Vardhman K; Down Thomas A; Thorne Natalie P; Flicek Paul; Kulesha Eugene; Gräf Stefan; Tomazou Eleni M; Bäckdahl Liselotte; Johnson Nathan; Herberth Marlis; Howe Kevin L; Jackson David K; Miretti Marcos M; Fiegler Heike; Marioni John C; Birney Ewan; Hubbard Tim J P; Carter Nigel P; Tavaré Simon; Beck Stephan
An integrated resource for genome-wide identification and analysis of human tissue-specific differentially methylated regions (tDMRs).
Genome research 2008;18(9):1518-29.
2008: Ito Yoko; Koessler Thibaud; Ibrahim Ashraf E K; Rai Sushma; Vowler Sarah L; Abu-Amero Sayeda; Silva Ana-Luisa; Maia Ana-Teresa; Huddleston Joanna E; Uribe-Lewis Santiago; Woodfine Kathryn; Jagodic Maja; Nativio Raffaella; Dunning Alison; Moore Gudrun; Klenova Elena; Bingham Sheila; Pharoah Paul D P; Brenton James D; Beck Stephan; Sandhu Manjinder S; Murrell Adele
Somatically acquired hypomethylation of IGF2 in breast and colorectal cancer.
Human molecular genetics 2008;17(17):2633-43.
2008: Butcher Lee M; Beck Stephan
Future impact of integrated high-throughput methylome analyses on human health and disease.
Journal of genetics and genomics = Yi chuan xue bao 2008;35(7):391-401.
2008: Down Thomas A; Rakyan Vardhman K; Turner Daniel J; Flicek Paul; Li Heng; Kulesha Eugene; Gräf Stefan; Johnson Nathan; Herrero Javier; Tomazou Eleni M; Thorne Natalie P; Bäckdahl Liselotte; Herberth Marlis; Howe Kevin L; Jackson David K; Miretti Marcos M; Marioni John C; Birney Ewan; Hubbard Tim J P; Durbin Richard; Tavaré Simon; Beck Stephan
A Bayesian deconvolution strategy for immunoprecipitation-based DNA methylome analysis.
Nature biotechnology 2008;26(7):779-85.
2008: Beck Stephan; Rakyan Vardhman K
The methylome: approaches for global DNA methylation profiling.
Trends in genetics : TIG 2008;24(5):231-7.
2008: Horton Roger; Gibson Richard; Coggill Penny; Miretti Marcos; Allcock Richard J; Almeida Jeff; Forbes Simon; Gilbert James G R; Halls Karen; Harrow Jennifer L; Hart Elizabeth; Howe Kevin; Jackson David K; Palmer Sophie; Roberts Anne N; Sims Sarah; Stewart C Andrew; Traherne James A; Trevanion Steve; Wilming Laurens; Rogers Jane; de Jong Pieter J; Elliott John F; Sawcer Stephen; Todd John A; Trowsdale John; Beck Stephan
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project.
Immunogenetics 2008;60(1):1-18.
2008: Turner Daniel J; Miretti Marcos; Rajan Diana; Fiegler Heike; Carter Nigel P; Blayney Martyn L; Beck Stephan; Hurles Matthew E
Germline rates of de novo meiotic deletions and duplications causing several genomic disorders.
Nature genetics 2008;40(1):90-5.
2008: Tomazou Eleni M; Rakyan Vardhman K; Lefebvre Gregory; Andrews Robert; Ellis Peter; Jackson David K; Langford Cordelia; Francis Matthew D; Bäckdahl Liselotte; Miretti Marcos; Coggill Penny; Ottaviani Diego; Sheer Denise; Murrell Adele; Beck Stephan
Generation of a genomic tiling array of the human major histocompatibility complex (MHC) and its application for DNA methylation analysis.
BMC medical genomics 2008;1():19.
2007: Sambrook Jennifer G; Beck Stephan
Evolutionary vignettes of natural killer cell receptors.
Current opinion in immunology 2007;19(5):553-60.
2007: Raval Aparna; Tanner Stephan M; Byrd John C; Angerman Elizabeth B; Perko James D; Chen Shih-Shih; Hackanson Björn; Grever Michael R; Lucas David M; Matkovic Jennifer J; Lin Thomas S; Kipps Thomas J; Murray Fiona; Weisenburger Dennis; Sanger Warren; Lynch Jane; Watson Patrice; Jansen Mary; Yoshinaga Yuko; Rosenquist Richard; de Jong Pieter J; Coggill Penny; Beck Stephan; Lynch Henry; de la Chapelle Albert; Plass Christoph
Downregulation of death-associated protein kinase 1 (DAPK1) in chronic lymphocytic leukemia.
Cell 2007;129(5):879-90.
2007: Yeo Tai Wai; De Jager Philip L; Gregory Simon G; Barcellos Lisa F; Walton Amie; Goris An; Fenoglio Chiara; Ban Maria; Taylor Craig J; Goodman Reyna S; Walsh Emily; Wolfish Cara S; Horton Roger; Traherne James; Beck Stephan; Trowsdale John; Caillier Stacy J; Ivinson Adrian J; Green Todd; Pobywajlo Susan; Lander Eric S; Pericak-Vance Margaret A; Haines Jonathan L; Daly Mark J; Oksenberg Jorge R; Hauser Stephen L; Compston Alastair; Hafler David A; Rioux John D; Sawcer Stephen
A second major histocompatibility complex susceptibility locus for multiple sclerosis.
Annals of neurology 2007;61(3):228-36.
2007: Bignone P A; Lee K Y; Liu Y; Emilion G; Finch J; Soosay A E R; Charnock F M L; Beck S; Dunham I; Mungall A J; Ganesan T S
RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer.
Oncogene 2007;26(5):683-700.
2006: Eckhardt Florian; Lewin Joern; Cortese Rene; Rakyan Vardhman K; Attwood John; Burger Matthias; Burton John; Cox Tony V; Davies Rob; Down Thomas A; Haefliger Carolina; Horton Roger; Howe Kevin; Jackson David K; Kunde Jan; Koenig Christoph; Liddle Jennifer; Niblett David; Otto Thomas; Pettett Roger; Seemann Stefanie; Thompson Christian; West Tony; Rogers Jane; Olek Alex; Berlin Kurt; Beck Stephan
DNA methylation profiling of human chromosomes 6, 20 and 22.
Nature genetics 2006;38(12):1378-85.
2006: Rakyan Vardhman K; Beck Stephan
Epigenetic variation and inheritance in mammals.
Current opinion in genetics & development 2006;16(6):573-7.
2006: Horton R; Coggill P; Miretti M M; Sambrook J G; Traherne J A; Ward R; Sims S; Palmer S; Sehra H; Harrow J; Rogers J; Carrington M; Trowsdale J; Beck S
The LRC haplotype project: a resource for killer immunoglobulin-like receptor-linked association studies.
Tissue antigens 2006;68(5):450-2.
2006: de Bakker Paul I W; McVean Gil; Sabeti Pardis C; Miretti Marcos M; Green Todd; Marchini Jonathan; Ke Xiayi; Monsuur Alienke J; Whittaker Pamela; Delgado Marcos; Morrison Jonathan; Richardson Angela; Walsh Emily C; Gao Xiaojiang; Galver Luana; Hart John; Hafler David A; Pericak-Vance Margaret; Todd John A; Daly Mark J; Trowsdale John; Wijmenga Cisca; Vyse Tim J; Beck Stephan; Murray Sarah Shaw; Carrington Mary; Gregory Simon; Deloukas Panos; Rioux John D
A high-resolution HLA and SNP haplotype map for disease association studies in the extended human MHC.
Nature genetics 2006;38(10):1166-72.
2006: Renard C; Hart E; Sehra H; Beasley H; Coggill P; Howe K; Harrow J; Gilbert J; Sims S; Rogers J; Ando A; Shigenari A; Shiina T; Inoko H; Chardon P; Beck S
The genomic sequence and analysis of the swine major histocompatibility complex.
Genomics 2006;88(1):96-110.
2006: Sambrook Jennifer G; Sehra Harminder; Coggill Penny; Humphray Sean; Palmer Sophie; Sims Sarah; Takamatsu Haru-Hisa; Wileman Thomas; Archibald Alan L; Beck Stephan
Identification of a single killer immunoglobulin-like receptor (KIR) gene in the porcine leukocyte receptor complex on chromosome 6q.
Immunogenetics 2006;58(5-6):481-6.
2006: Laun Katja; Coggill Penny; Palmer Sophie; Sims Sarah; Ning Zemin; Ragoussis Jiannis; Volpi Emanuela; Wilson Natalie; Beck Stephan; Ziegler Andreas; Volz Armin
The leukocyte receptor complex in chicken is characterized by massive expansion and diversification of immunoglobulin-like Loci.
PLoS genetics 2006;2(5):e73.
2006: Miretti Marcos M; Beck Stephan
Immunogenomics: molecular hide and seek.
Human genomics 2006;2(4):244-51.
2006: Traherne James A; Horton Roger; Roberts Anne N; Miretti Marcos M; Hurles Matthew E; Stewart C Andrew; Ashurst Jennifer L; Atrazhev Alexey M; Coggill Penny; Palmer Sophie; Almeida Jeff; Sims Sarah; Wilming Laurens G; Rogers Jane; de Jong Pieter J; Carrington Mary; Elliott John F; Sawcer Stephen; Todd John A; Trowsdale John; Beck Stephan
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history.
PLoS genetics 2006;2(1):e9.
2006: Deakin Janine E; Papenfuss Anthony T; Belov Katherine; Cross Joseph G R; Coggill Penny; Palmer Sophie; Sims Sarah; Speed Terence P; Beck Stephan; Graves Jennifer A Marshall
Evolution and comparative analysis of the MHC Class III inflammatory region.
BMC genomics 2006;7():281.
2006: Sambrook Jennifer G; Bashirova Arman; Andersen Hanne; Piatak Mike; Vernikos George S; Coggill Penny; Lifson Jeff D; Carrington Mary; Beck Stephan
Identification of the ancestral killer immunoglobulin-like receptor gene in primates.
BMC genomics 2006;7():209.
2005: Ke Xiayi; Miretti Marcos M; Broxholme John; Hunt Sarah; Beck Stephan; Bentley David R; Deloukas Panos; Cardon Lon R
A comparison of tagging methods and their tagging space.
Human molecular genetics 2005;14(18):2757-67.
2005: Murrell Adele; Rakyan Vardhman K; Beck Stephan
From genome to epigenome.
Human molecular genetics 2005;14 Spec No 1():R3-R10.
2005: Miretti Marcos M; Walsh Emily C; Ke Xiayi; Delgado Marcos; Griffiths Mark; Hunt Sarah; Morrison Jonathan; Whittaker Pamela; Lander Eric S; Cardon Lon R; Bentley David R; Rioux John D; Beck Stephan; Deloukas Panos
A high-resolution linkage-disequilibrium map of the human major histocompatibility complex and first generation of tag single-nucleotide polymorphisms.
American journal of human genetics 2005;76(4):634-46.
2005: Sambrook Jennifer G; Bashirova Arman; Palmer Sophie; Sims Sarah; Trowsdale John; Abi-Rached Laurent; Parham Peter; Carrington Mary; Beck Stephan
Single haplotype analysis demonstrates rapid evolution of the killer immunoglobulin-like receptor (KIR) loci in primates.
Genome research 2005;15(1):25-35.
2005: Sambrook Jennifer G; Figueroa Felipe; Beck Stephan
A genome-wide survey of Major Histocompatibility Complex (MHC) genes and their paralogues in zebrafish.
BMC genomics 2005;6():152.
2005: Cross J G R; Harrison G A; Coggill P; Sims S; Beck S; Deakin J E; Graves J A Marshall
Analysis of the genomic region containing the tammar wallaby (Macropus eugenii) orthologues of MHC class III genes.
Cytogenetic and genome research 2005;111(2):110-7.
2004: Horton Roger; Wilming Laurens; Rand Vikki; Lovering Ruth C; Bruford Elspeth A; Khodiyar Varsha K; Lush Michael J; Povey Sue; Talbot C Conover; Wright Mathew W; Wain Hester M; Trowsdale John; Ziegler Andreas; Beck Stephan
Gene map of the extended human MHC.
Nature reviews. Genetics 2004;5(12):889-99.
2004: Rakyan Vardhman K; Hildmann Thomas; Novik Karen L; Lewin Jörn; Tost Jörg; Cox Antony V; Andrews T Dan; Howe Kevin L; Otto Thomas; Olek Alexander; Fischer Judith; Gut Ivo G; Berlin Kurt; Beck Stephan
DNA methylation profiling of the human major histocompatibility complex: a pilot study for the human epigenome project.
PLoS biology 2004;2(12):e405.
2004: Eckhardt Florian; Beck Stephan; Gut Ivo G; Berlin Kurt
Future potential of the Human Epigenome Project.
Expert review of molecular diagnostics 2004;4(5):609-18.
2004: Stewart C Andrew; Horton Roger; Allcock Richard J N; Ashurst Jennifer L; Atrazhev Alexey M; Coggill Penny; Dunham Ian; Forbes Simon; Halls Karen; Howson Joanna M M; Humphray Sean J; Hunt Sarah; Mungall Andrew J; Osoegawa Kazutoyo; Palmer Sophie; Roberts Anne N; Rogers Jane; Sims Sarah; Wang Yu; Wilming Laurens G; Elliott John F; de Jong Pieter J; Sawcer Stephen; Todd John A; Trowsdale John; Beck Stephan
Complete MHC haplotype sequencing for common disease gene mapping.
Genome research 2004;14(6):1176-87.
2003: Amadou Claire; Younger Ruth M; Sims Sarah; Matthews Lucy H; Rogers Jane; Kumanovics Attila; Ziegler Andreas; Beck Stephan; Lindahl Kirsten Fischer
Co-duplication of olfactory receptor and MHC class I genes in the mouse major histocompatibility complex.
Human molecular genetics 2003;12(22):3025-40.
2003: Volz Armin; Ehlers Anke; Younger Ruth; Forbes Simon; Trowsdale John; Schnorr Dietmar; Beck Stephan; Ziegler Andreas
Complex transcription and splicing of odorant receptor genes.
The Journal of biological chemistry 2003;278(22):19691-701.
2003: Allcock Richard J N; Barrow Alexander D; Forbes Simon; Beck Stephan; Trowsdale John
The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44.
European journal of immunology 2003;33(2):567-77.
2003: Beck Stephan
Immunogenomics: towards a digital immune system.
Novartis Foundation symposium 2003;254():223-30; discussion 230-3, 250-2.
2003: Beck Stephan
The Human Genome Project: what we have learnt about the MHC region on chromosome 6 and its potential to Behçet's disease.
Advances in experimental medicine and biology 2003;528():207-11.
2002: Novik K L; Nimmrich I; Genc B; Maier S; Piepenbrock C; Olek A; Beck S
Epigenomics: genome-wide study of methylation phenomena.
Current issues in molecular biology 2002;4(4):111-28.
2002: Liu Ying; Dodds Phillippa; Emilion Gracy; Mungall Andrew J; Dunham Ian; Beck Stephan; Wells R Spencer; Charnock F Mark L; Ganesan Trivadi S
The human homologue of unc-93 maps to chromosome 6q27 - characterisation and analysis in sporadic epithelial ovarian cancer.
BMC genetics 2002;3():20.
2002: Allcock R J N; Atrazhev A M; Beck S; de Jong P J; Elliott J F; Forbes S; Halls K; Horton R; Osoegawa K; Rogers J; Sawcer S; Todd J A; Trowsdale J; Wang Y; Williams S
The MHC haplotype project: a resource for HLA-linked association studies.
Tissue antigens 2002;59(6):520-1.
2002: Liu Ying; Emilion Gracy; Mungall Andrew J; Dunham Ian; Beck Stephan; Le Meuth-Metzinger Valerie G; Shelling Andrew N; Charnock Francis M L; Ganesan Trivadi S
Physical and transcript map of the region between D6S264 and D6S149 on chromosome 6q27, the minimal region of allele loss in sporadic epithelial ovarian cancer.
Oncogene 2002;21(3):387-99.
2001: Trowsdale J; Barten R; Haude A; Stewart C A; Beck S; Wilson M J
The genomic context of natural killer receptor extended gene families.
Immunological reviews 2001;181():20-38.
2001: Younger R M; Amadou C; Bethel G; Ehlers A; Lindahl K F; Forbes S; Horton R; Milne S; Mungall A J; Trowsdale J; Volz A; Ziegler A; Beck S
Characterization of clustered MHC-linked olfactory receptor genes in human and mouse.
Genome research 2001;11(4):519-30.
2001: Rhodes D A; Stammers M; Malcherek G; Beck S; Trowsdale J
The cluster of BTN genes in the extended major histocompatibility complex.
Genomics 2001;71(3):351-62.
2000: Torkar M; Haude A; Milne S; Beck S; Trowsdale J; Wilson M J
Arrangement of the ILT gene cluster: a common null allele of the ILT6 gene results from a 6.7-kbp deletion.
European journal of immunology 2000;30(12):3655-62.
2000: Ziegler A; Ehlers A; Forbes S; Trowsdale J; Volz A; Younger R; Beck S
Polymorphisms in olfactory receptor genes: a cautionary note.
Human immunology 2000;61(12):1281-4.
2000: Ehlers A; Beck S; Forbes S A; Trowsdale J; Volz A; Younger R; Ziegler A
MHC-linked olfactory receptor loci exhibit polymorphism and contribute to extended HLA/OR-haplotypes.
Genome research 2000;10(12):1968-78.
2000: Stammers M; Rowen L; Rhodes D; Trowsdale J; Beck S
BTL-II: a polymorphic locus with homology to the butyrophilin gene family, located at the border of the major histocompatibility complex class II and class III regions in human and mouse.
Immunogenetics 2000;51(4-5):373-82.
2000: Wilson M J; Torkar M; Haude A; Milne S; Jones T; Sheer D; Beck S; Trowsdale J
Plasticity in the organization and sequences of human KIR/ILT gene families.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(9):4778-83.
2000: Beck S; Trowsdale J
The human major histocompatability complex: lessons from the DNA sequence.
Annual review of genomics and human genetics 2000;1():117-37.
2000: Mungall A J; Beck S; Cann H M; Dunham I; Trowsdale J; Ziegler A
Report of the Fourth International Chromosome 6 Workshop 1999. 10-12 June 1999. Cambridge, UK. Abstracts.
Cytogenetics and cell genetics 2000;88(3-4):173-96.
1999: Stephens R; Horton R; Humphray S; Rowen L; Trowsdale J; Beck S
Gene organisation, sequence variation and isochore structure at the centromeric boundary of the human MHC.
Journal of molecular biology 1999;291(4):789-99.
1999: Janitz K; Wild A; Beck S; Savasta S; Beluffi G; Ziegler A; Volz A
Genomic organization of the HSET locus and the possible association of HLA-linked genes with immotile cilia syndrome (ICS).
Immunogenetics 1999;49(7-8):644-52.
1999: Thorpe K L; Schafer A J; Génin E; Trowsdale J; Beck S
Detection of polymorphism in the RING3 gene by high-throughput fluorescent SSCP analysis.
Immunogenetics 1999;49(4):256-65.
1998: Horton R; Niblett D; Milne S; Palmer S; Tubby B; Trowsdale J; Beck S
Large-scale sequence comparisons reveal unusually high levels of variation in the HLA-DQB1 locus in the class II region of the human MHC.
Journal of molecular biology 1998;282(1):71-97.
1998: Thorpe K L; Beck S
DNA sequence and structure of the mouse RING3 gene: identification of variant RING3 transcripts.
Immunogenetics 1998;48(1):82-6.
1997: Thorpe K L; Gorman P; Thomas C; Sheer D; Trowsdale J; Beck S
Chromosomal localization, gene structure and transcription pattern of the ORFX gene, a homologue of the MHC-linked RING3 gene.
Gene 1997;200(1-2):177-83.
1997: Theaker A J; Maslen G L; Scott C E; Rice C M; Hunt S E; King A; Mungall A J; Dunham I; Beck S
The Chromosome 6 database at the Sanger Centre.
DNA sequence : the journal of DNA sequencing and mapping 1997;8(3):167-71.
1997: Beck S; Cann H M; Campbell R D; Dunham I; Inoko H; Jazwinska E C; Ragoussis J; Trowsdale J; Ziegler A
Third single chromosome 6 workshop: meeting report.
DNA sequence : the journal of DNA sequencing and mapping 1997;8(3):113-29.

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Stephan Beck

Research Profile (preview)

Genes & Molecular Sequences

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Physiology

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Network (preview)

Publications

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